Other disorders of peripheral nervous system

G6_PERIPHOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G64
  • Cause of death: ICD-10 G64

2 out of 7 registries used, show all original rules.

231

4. Check minimum number of events

None

231

5. Include endpoints

None

231

6. Filter based on genotype QC (FinnGen only)

224

Control definitions (FinnGen only)

Control exclude
G6_POLYNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G60-G64
Name in latin
Aliae morbositates systematis nervosi peripherici

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1252 584 661
Only index persons 1109 536 573
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 59.48 59.38 59.73
Only index persons 57.53 58.02 57.07

-FinnGen-

Key figures

All Female Male
Number of individuals 224 119 105
Unadjusted period prevalence (%) 0.04 0.04 0.05
Median age at first event (years) 59.15 56.79 61.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
231
Matched controls
2310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G64
ICD-10 Finland
Other disorders of peripheral nervous system
+∞
307.7
230
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
108.3
48.1
51
6
N03AX12
ATC
[U] gabapentin; oral
5.8
36.2
91
231
N03AX16
ATC
[U] pregabalin
4.8
30.3
104
336
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
6.7
20.8
36
62
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.4
20.2
45
99
N06AX21
ATC
duloxetine; oral
4.6
19.8
57
155
G62.8
ICD-10 Finland
Other specified polyneuropathies
194.3
17.8
18
*
TAB00
NOMESCO Finland
Lumbar puncture
6.0
16.4
31
58
N02BF02
ATC
pregabalin; oral
6.1
16.2
30
55
R20.2
ICD-10 Finland
Paraesthesia of skin
5.1
16.1
37
83
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.1
14.3
44
124
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
13.1
108
553
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.5
12.3
25
50
L28
ICPC
Limited function/disability (L)
3.1
11.8
59
228
N03AE01
ATC
clonazepam; systemic
4.7
10.3
25
58
AA1AD
NOMESCO Finland
CT of head and brain
2.6
10.2
83
412
N02AX02
ATC
tramadol; systemic, rectal
2.4
10.0
122
727
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
9.7
36
115
R42
ICD-10 Finland
Dizziness and giddiness
2.6
9.3
68
319
R52.2
ICD-10 Finland
Other chronic pain
5.1
8.8
19
40
N06AX11
ATC
mirtazapine; oral
2.3
8.7
96
541
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.7
8.6
52
221
M79.6
ICD-10 Finland
Pain in limb
2.3
8.5
114
695
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
8.4
32
104
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
8.2
82
440
N06AA09
ATC
amitriptyline; systemic
3.1
7.8
34
120
H02AB06
ATC
prednisolone; systemic
2.2
7.7
127
830
N02BF01
ATC
gabapentin; oral
3.3
7.7
31
104
N99
ICPC
Neurological disease other
19.2
7.7
11
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
7.7
122
787
A01
ICPC
Pain general/multiple sites
3.2
7.5
32
111
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
7.4
57
271
G61.8
ICD-10 Finland
Other inflammatory polyneuropathies
+∞
7.3
7
*
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
+∞
7.3
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
7.1
60
297
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
7.1
74
401
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
7.0
80
449
A28
ICPC
Limited function/disability NOS
2.5
7.0
52
243
M54.5
ICD-10 Finland
Low back pain
2.1
6.8
92
550
A04
ICPC
Weakness/tiredness general
2.6
6.7
41
174
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
9.1
6.6
13
15
ACC51
NOMESCO Finland
Release of median nerve
3.5
6.6
24
75
N06AX16
ATC
venlafaxine; oral
2.6
6.6
41
175
R52.9
ICD-10 Finland
Pain, unspecified
2.9
6.3
32
123
H02AB07
ATC
prednisone; oral
2.6
6.2
39
168
N28
ICPC
Limited function/disability (N)
13.0
6.1
10
8
R02
ICPC
Shortness of breath/dyspnoea
2.6
6.1
38
162
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
6.1
29
107
M48.0
ICD-10 Finland
Spinal stenosis
2.6
6.1
39
169
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
6.1
54
272
R4110
NOMESCO Finland
Physiotherapy
2.1
6.0
75
432
R5110, ,
SPAT
3.6
6.0
20
59
N03AX09
ATC
lamotrigine; oral
4.2
6.0
16
40

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
115
6.25
28.51
3.1
2.7
—
—
—
0
0
52
118
5.40
22.62
2.4
2.4
—
15.54
—
0
7
47
102
5.53
21.43
1.3
1.3
—
31.40
—
0
9
135
728
3.06
15.50
2.4
1.9
94.86
94.98
pmol/l
0.01
76
366
113
573
2.90
14.18
2.6
2.0
204.65
198.92
u/l
0.03
105
537
58
223
3.14
11.69
1.3
1.3
440.00
564.29
titre
—
7
56
133
807
2.53
10.75
5.8
4.3
35.54
35.62
g/l
0.06
125
754
136
834
2.53
10.74
11.2
5.8
1.22
1.21
mmol/l
0.09
129
755
21
41
5.53
10.53
1.2
1.2
5.13
159.72
e6/l
0.54
15
32
21
41
5.53
10.53
1.2
1.1
1.47
2.79
e6/l
1.14
15
29
146
947
2.47
9.90
6.7
5.5
1.71
1.85
e9/l
0.99
131
838
143
926
2.43
9.62
6.8
5.5
0.04
0.04
e9/l
0.29
126
794
19
37
5.51
9.53
1.2
1.2
—
—
—
0
0
141
910
2.41
9.52
7.9
6.9
1.22
1.21
mmol/l
0.22
123
771
142
924
2.39
9.35
6.8
5.5
0.58
0.58
e9/l
0.03
126
791
159
1089
2.48
9.30
10.6
10.0
4.23
4.13
e9/l
0.21
143
949
79
398
2.50
9.27
1.3
1.2
1.78
1.63
u/ml
0.04
12
115
63
287
2.64
9.09
4.3
3.3
0.79
0.82
mmol/l
1.46
57
267
99
560
2.34
8.91
4.7
4.0
7.39
7.40
ph
0.64
15
103
144
958
2.34
8.79
7.0
6.0
0.17
0.19
e9/l
0.70
131
844
149
1017
2.31
8.40
7.6
6.6
10.40
11.33
umol/l
0.88
144
962
134
876
2.26
8.38
7.3
5.9
—
—
—
0
0
132
861
2.24
8.26
7.5
5.4
2.68
2.83
%
0.38
126
800
83
448
2.33
8.20
1.9
1.6
19.88
20.93
nmol/l
0.28
75
378
129
836
2.23
8.17
7.2
5.3
0.72
0.69
%
0.27
124
771
132
866
2.22
8.08
7.9
5.7
8.70
8.61
%
0.12
127
808
80
429
2.32
8.00
2.6
2.0
2.44
3.34
mg/l
3.82
71
367
133
884
2.19
7.77
7.8
5.5
26.15
27.33
%
0.58
128
826
37
139
2.98
7.60
1.1
1.2
—
—
—
0
0
167
1228
2.30
7.43
5.3
4.3
—
365.52
—
0
21
102
630
2.11
7.00
4.2
3.4
2.35
2.36
mmol/l
0.37
92
549
46
205
2.55
6.81
1.7
2.9
1.60
1.88
%
1.62
41
188
11
10
11.48
6.36
1.8
1.5
—
—
—
0
0
179
1396
2.25
6.29
5.9
4.1
13.29
11.89
mm/h
0.60
171
1276
16
39
4.33
6.19
1.4
1.4
—
—
—
0
0
64
347
2.17
6.01
1.7
1.4
2.28
2.63
g/l
0.47
37
208
129
906
1.96
5.87
18.6
12.9
1.23
1.28
inr
0.25
38
257
114
768
1.96
5.86
3.6
2.6
131.96
129.99
ug/l
0.03
108
697
63
345
2.14
5.75
1.7
1.7
1078.92
1238.65
nmol/l
0.67
54
256
12
17
7.38
5.51
1.8
3.9
—
—
—
0
0
83
510
1.98
5.51
5.6
4.1
—
—
—
0
0
165
1278
2.02
5.46
3.8
3.0
54.67
47.00
u/l
0.39
156
1195
49
248
2.24
5.41
2.4
2.3
23.42
22.78
%
0.12
42
209
38
172
2.45
5.40
2.7
2.3
84.23
30.10
u/l
0.46
30
145
35
153
2.52
5.35
1.8
3.1
59.82
74.07
e9/l
2.81
25
124
166
1293
2.01
5.35
5.8
4.3
—
—
—
0
0
80
498
1.93
5.04
4.0
2.7
—
—
—
0
0
16
38
4.45
4.93
3.7
4.9
—
—
—
0
0
10
13
7.98
4.90
1.0
1.2
—
—
—
0
0
67
396
1.97
4.89
2.5
2.4
7.22
4.50
e6/l
0.74
61
355
67
399
1.96
4.78
1.8
1.6
0.97
1.25
mg/l
0.58
47
317
82
526
1.87
4.65
4.1
2.8
0.50
0.35
e6/l
0.40
70
392
33
151
2.38
4.57
5.0
6.5
8.41
9.53
mmol/l
0.44
33
143
52
288
2.04
4.52
3.9
2.9
3.34
2.31
e6/l
0.29
29
157
13
28
4.85
4.44
1.0
1.2
—
—
—
0
0
15
46
3.42
4.27
1.5
1.4
—
—
—
0
0
12
26
4.81
4.12
2.7
3.2
—
—
—
0
0
7
7
10.26
4.03
1.0
1.0
117.43
151.43
nmol/l
—
7
7
65
405
1.84
3.96
1.7
1.8
410.12
441.06
pmol/l
0.51
57
333
85
575
1.76
3.94
4.2
3.0
85.91
165.54
e6/l
0.27
71
449
15
49
3.20
3.88
1.5
1.3
—
—
—
0
0
15
49
3.20
3.88
1.6
1.3
—
—
—
0
0
15
49
3.20
3.88
1.6
1.3
—
—
—
0
0
15
50
3.14
3.76
1.6
1.3
—
—
—
0
0
10
20
5.17
3.73
1.5
1.5
—
—
—
0
0
90
627
1.71
3.72
2.9
2.3
49.78
55.38
u/l
1.25
85
581
94
663
1.70
3.71
5.0
3.6
26.79
82.45
e6/l
1.77
77
481
124
942
1.68
3.70
3.8
3.7
0.00
0.00
estimate
-0.00
20
165
64
405
1.80
3.69
3.4
4.0
1.02
1.02
kg/l
0.15
14
52
51
302
1.88
3.62
1.8
1.7
—
—
—
0
0
7
9
7.98
3.58
1.3
1.3
1707.14
1479.44
ml
—
7
9
80
545
1.72
3.56
3.7
3.2
3250.46
164.44
mg/l
1.27
53
342
122
931
1.66
3.51
4.9
4.9
0.00
0.00
estimate
-0.00
21
173
170
1416
1.76
3.51
3.9
3.9
15.17
14.88
pmol/l
0.73
154
1276
199
1741
2.03
3.49
5.2
4.6
1.63
1.92
mu/l
3.70
185
1582
40
221
1.98
3.47
1.9
1.4
—
—
—
0
0
10
22
4.70
3.47
1.4
1.1
—
—
—
0
0
82
570
1.68
3.35
3.6
3.1
7.85
7.63
mmol/l
0.15
70
468
57
358
1.79
3.34
7.6
3.4
407.57
153.28
ng/l
0.59
46
280
70
467
1.72
3.33
9.2
7.7
—
—
—
0
0
63
413
1.72
3.17
4.1
3.6
—
—
—
0
0
101
751
1.61
3.12
4.9
3.7
74.28
36.50
ng/l
0.39
74
524
6
8
7.66
3.07
1.5
1.8
—
—
—
0
0
6
8
7.66
3.07
1.0
1.4
1.97
2.00
mmol/l
—
6
8
51
322
1.75
2.91
1.4
1.3
29.01
36.13
iu/ml
0.22
15
99
12
38
3.27
2.90
1.5
1.4
—
—
—
0
0
118
927
1.56
2.80
3.7
3.7
0.00
0.01
estimate
0.50
21
186
58
384
1.68
2.79
2.4
2.9
486.69
547.94
mosm/kgh2o
1.38
52
331
5
6
8.48
2.76
1.4
1.0
—
—
—
0
0
79
574
1.57
2.60
3.2
2.9
—
—
—
0
0
208
1894
1.99
2.56
24.3
13.8
23.35
22.88
mg/l
0.08
182
1499
6
11
5.57
2.56
1.2
1.3
77.50
154.15
mmol/24h
—
6
11
37
224
1.78
2.43
2.3
1.6
—
—
—
0
0
49
706
0.61
2.41
2.8
3.0
—
—
—
0
0
156
1328
1.54
2.40
4.2
4.0
—
—
—
0
0
36
218
1.77
2.37
15.5
7.7
1.98
1.14
mmol/l
0.59
28
174
13
53
2.54
2.32
1.6
1.5
306.25
300.25
ug/g
—
8
29
10
34
3.03
2.31
1.6
1.8
—
—
—
0
0
23
121
2.00
2.30
4.2
2.2
—
—
—
0
0
6
13
4.71
2.28
1.7
1.5
—
—
—
0
0
78
580
1.52
2.27
4.4
3.8
11.48
7.44
mg/mmol
0.34
48
357
8
24
3.41
2.20
1.5
1.2
—
—
—
0
0
29
169
1.82
2.16
2.3
3.7
5.88
5.74
kpa
0.38
29
163
14
63
2.30
2.05
1.4
1.6
—
—
—
0
0
29
174
1.76
1.98
2.8
3.8
—
—
—
0
0
35
224
1.66
1.90
15.3
6.8
105.34
104.12
mmol/l
1.31
35
224
67
499
1.48
1.90
2.1
2.8
330.68
8019.73
umol/l
2.44
60
430
201
1848
1.68
1.89
4.8
4.7
6.13
5.98
mmol/l
0.63
189
1684
37
241
1.64
1.88
1.2
1.3
—
—
—
0
0
6
17
3.59
1.85
1.3
1.2
—
—
—
0
0
79
611
1.45
1.84
3.1
2.2
—
—
—
0
0
44
301
1.57
1.84
1.3
1.3
1.24
11.29
u/ml
1.45
15
106
31
194
1.69
1.83
1.7
1.5
—
—
—
0
0
23
132
1.82
1.81
18.4
4.8
—
—
—
0
0
215
2019
1.94
1.80
28.6
16.4
75.11
77.63
umol/l
0.84
215
2019
11
48
2.36
1.73
1.0
1.2
—
—
—
0
0
40
272
1.57
1.72
3.6
1.9
—
—
—
0
0
18
97
1.93
1.71
11.4
9.3
—
—
—
0
0
8
31
2.64
1.67
1.8
1.9
71.17
61.69
%
—
8
31
6
19
3.21
1.67
1.3
1.2
—
—
—
0
0
6
19
3.21
1.67
1.7
1.4
—
—
—
0
0
100
820
1.39
1.64
10.5
9.2
0.00
0.00
e9/l
0.55
80
662
10
42
2.44
1.64
2.7
2.5
—
—
—
0
0
67
513
1.43
1.63
1.6
1.7
1.47
1.37
mmol/l
0.49
62
423
7
26
2.74
1.59
1.1
1.2
—
—
—
0
0
29
186
1.64
1.58
1.5
1.6
—
—
—
0
0
10
44
2.33
1.57
3.8
1.9
—
—
—
0
0
35
239
1.55
1.48
1.7
1.5
—
—
—
0
0
6
22
2.77
1.44
1.0
1.6
—
—
—
0
0
14
74
1.95
1.42
25.5
3.9
—
—
—
0
0
10
194
0.49
1.39
1.4
1.4
—
—
—
0
0
21
128
1.70
1.39
1.4
1.5
—
—
—
0
0
33
226
1.54
1.39
3.2
2.0
110.04
124.23
ug/g
0.16
26
183
5
17
2.98
1.36
1.2
1.3
—
—
—
0
0
33
229
1.51
1.31
4.2
4.5
28.69
26.57
ug/l
0.02
26
187
92
766
1.33
1.31
2.0
2.1
—
—
—
0
0
18
107
1.74
1.30
1.1
1.3
—
—
—
0
0
5
18
2.82
1.29
3.2
2.6
—
—
—
0
0
14
77
1.87
1.28
3.5
1.6
—
—
—
0
0
22
141
1.62
1.22
2.2
2.8
4.68
4.33
kpa
0.32
22
136
16
94
1.75
1.21
2.1
2.6
0.64
0.66
%
0.08
16
94
22
143
1.60
1.16
6.2
8.3
—
—
—
0
0
8
40
2.04
1.13
3.4
2.9
—
—
—
0
0
63
506
1.34
1.13
4.0
3.9
0.00
0.00
estimate
-0.00
21
170
33
237
1.46
1.13
1.2
1.2
—
—
—
0
0
25
170
1.53
1.10
5.2
4.5
—
—
—
0
0
5
22
2.30
1.04
1.8
1.8
33.80
33.09
pg
—
5
22
16
99
1.66
1.03
2.1
2.5
1.73
1.17
%
1.04
16
99
7
35
2.03
1.01
1.1
1.3
—
—
—
0
0
191
1796
1.37
1.00
6.4
5.8
40.51
40.11
mmol/mol
0.21
184
1673
5
23
2.20
0.98
1.6
1.9
—
—
—
0
0
20
134
1.54
0.95
4.8
3.2
5.06
5.04
kpa
0.07
20
129
20
134
1.54
0.95
2.2
3.8
73.83
80.23
ng/l
0.18
14
114
6
27
2.25
0.94
1.0
1.4
—
—
—
0
0
10
55
1.86
0.93
1.8
3.5
—
—
—
0
0
63
523
1.28
0.88
2.6
3.4
—
—
—
0
0
8
43
1.89
0.88
1.7
1.1
—
—
—
0
0
208
1997
1.42
0.82
20.8
13.1
—
—
—
0
0
14
90
1.59
0.80
1.3
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
3.4
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
15
99
1.55
0.77
5.0
3.0
—
—
—
0
0
5
24
2.11
0.75
1.6
1.6
15.00
19.10
ug/l
—
5
24
21
152
1.42
0.72
3.9
4.0
0.86
1.08
%
—
7
65
217
2107
1.49
0.71
34.9
20.7
40.36
40.36
%
0.00
202
1978
11
168
0.64
0.70
1.1
1.4
—
—
—
0
0
66
566
1.23
0.70
4.4
4.1
—
—
—
0
0
16
112
1.46
0.65
1.3
1.2
—
—
—
0
0
7
113
0.61
0.59
1.4
1.5
—
—
—
0
0
18
135
1.36
0.53
3.6
4.1
1.20
0.41
%
—
5
53
11
75
1.49
0.51
2.5
2.5
—
—
—
0
0
18
137
1.34
0.49
1.4
1.6
—
—
—
0
0
57
500
1.19
0.48
1.4
1.4
—
—
—
0
0
28
228
1.26
0.48
1.3
1.3
—
—
—
0
0
7
47
1.50
0.48
1.1
1.3
—
—
—
0
0
23
183
1.29
0.47
1.4
1.4
—
—
—
0
0
8
56
1.44
0.43
1.5
1.8
291.00
322.66
mu/l
—
8
50
13
96
1.38
0.42
2.4
2.3
—
—
—
0
0
5
32
1.57
0.42
1.4
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
22.4
—
1887.06
—
0
16
0
16
0.00
0.41
0.0
13.1
—
1013.56
—
0
16
0
17
0.00
0.41
0.0
2.6
—
7.52
—
0
12
8
60
1.35
0.40
1.6
2.3
1.60
1.58
mg/l
—
8
52
20
160
1.27
0.40
5.0
3.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
198
1927
1.19
0.38
5.3
5.1
2.62
2.77
mmol/l
1.72
188
1770
73
675
1.12
0.30
4.7
4.9
1.78
2.66
ug/l
0.85
67
599
194
1893
1.16
0.30
4.7
4.6
4.47
4.67
mmol/l
2.22
184
1752
193
1885
1.15
0.28
4.6
4.5
1.42
1.46
mmol/l
0.75
180
1737
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
8.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
86.20
—
0
10
5
43
1.17
0.21
1.2
1.2
0.73
0.94
nmol/l
—
5
36
0
13
0.00
0.21
0.0
6.8
—
—
—
0
0
43
396
1.11
0.20
2.6
2.9
0.63
0.76
ug/l
0.48
34
251
6
53
1.14
0.19
1.2
1.1
—
—
—
0
0
10
83
1.21
0.15
1.1
1.1
—
—
—
0
0
18
162
1.12
0.12
3.8
3.5
—
—
—
0
0
17
154
1.11
0.10
1.9
1.4
—
—
—
0
0
5
48
1.04
0.09
1.2
1.3
—
—
—
0
0
5
64
0.78
0.08
1.0
1.2
—
—
—
0
0
8
77
1.04
0.07
1.3
1.6
—
—
—
0
0
19
178
1.07
0.06
1.2
1.4
—
—
—
0
0
183
1823
1.02
0.01
4.4
4.1
1.26
1.30
mmol/l
0.45
173
1671
10
97
1.03
0.00
3.7
4.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
7
75
0.93
-0.00
9.1
11.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
98
0.92
-0.00
5.3
2.9
11.44
46.47
u/ml
—
9
93
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
69
1.01
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
17.32
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_PERIPHOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_PERIPHOTH 1.811 [1.42, 2.32] < 0.001
Birth year 0.991 [0.98, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 143 out of 508 females with G6_PERIPHOTH died.

Males

Parameter HR [95% CI] p-value
G6_PERIPHOTH 2.226 [1.7, 2.91] < 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 563 males with G6_PERIPHOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_PERIPHOTH.

N-year risk Females Males
1 0.178% 0.322%
5 0.962% 2.451%
10 2.551% 6.395%
15 4.571% 12.048%
20 7.489% 19.046%

Relationships between endpoints

Index endpoint: G6_PERIPHOTH – Other disorders of peripheral nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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