This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Carcinoma in situ of middle ear and respiratory system
CD2_INSITU_EAR_RESP_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpoints |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D00-D09
- Name in latin
- Carcinoma in situ auris mediae sive systematis respiratorii
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of middle ear and respiratory system
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of middle ear and respiratory system
- In situ neoplasms
- In situ neoplasms
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 165 | 44 | 121 |
| Unadjusted period prevalence (%) | 0.04 | 0.01 | 0.05 |
| Median age at first event (years) | 68.56 | 66.30 | 69.39 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 158
- Matched controls
- 1581
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D02.0
ICD-10 Finland
Carcinoma in situ: Larynx
+∞
52.0
47
*
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
50.8
46
*
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
128.4
44.6
46
5
130
Kela drug reimbursment
Malignant tumour
+∞
40.4
37
*
WF002
NOMESCO Finland
Radical radiotherapy
384.9
32.1
31
*
DQA10
NOMESCO Finland
Biopsy of larynx
369.0
31.0
30
*
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
122.5
28.8
30
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
91.7
27.9
30
*
ZXC10
NOMESCO Finland
Use of laser
42.4
25.4
31
9
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
11.5
25.2
50
61
UDQ12
NOMESCO Finland
Flexible laryngoscopy
15.8
24.0
40
33
UGC12
NOMESCO Finland
Flexible bronchoscopy
11.3
22.4
44
52
J38.3
ICD-10 Finland
Other diseases of vocal cords
133.6
22.2
23
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
253.7
22.2
22
*
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
+∞
21.3
20
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
6.0
21.0
70
184
C32.9
ICD-10 Finland
Malignant neoplasm: Larynx, unspecified
+∞
20.2
19
*
UDQ22
NOMESCO Finland
Microlaryngoscopy
80.0
19.2
21
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
19.1
18
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
214.4
19.0
19
*
8070/2-C32.0
ICD-O-3
Squamous cell carcinoma in situ, NOS, of glottis
+∞
18.1
17
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
18.1
17
*
J37.0
ICD-10 Finland
Chronic laryngitis
29.6
17.5
23
9
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
17.0
16
*
XX3DW
NOMESCO Finland
Time consuming IT work
10.9
16.4
32
36
8140/2-C34.1
ICD-O-3
Adenocarcinoma in situ, NOS, of upper lobe, lung
+∞
15.9
15
*
A03FA01
ATC
metoclopramide; systemic, rectal
7.6
15.2
37
61
H02AB02
ATC
dexamethasone; systemic
63.0
15.1
17
*
C320, 8077, 2
ICD-O-3
NA
+∞
14.8
14
*
8070/3-C32.0
ICD-O-3
Squamous cell carcinoma, NOS, of glottis
+∞
14.8
14
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
13.7
13
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
14.8
13.4
22
17
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
12.7
12
*
UJC01
NOMESCO Finland
Scopy of lower throat
50.9
12.1
14
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
50.9
12.1
14
*
WZC30
NOMESCO Finland
Teaching
6.8
12.0
31
55
D02.2
ICD-10 Finland
Carcinoma in situ: Bronchus and lung
+∞
11.6
11
*
D02.3
ICD-10 Finland
Carcinoma in situ: Other parts of respiratory system
+∞
11.6
11
*
DQB70
NOMESCO Finland
Total excision of vocal cord
+∞
11.6
11
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
11.6
11
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
22.0
11.4
16
8
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.8
10.9
25
37
WX408
NOMESCO Finland
General anesthesy, balanced
3.7
10.6
54
194
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
117.5
10.6
11
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
10.5
10
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
10.5
10
*
116
Kela drug reimbursment
Prostate cancer
+∞
10.5
10
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
10.5
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.3
10.4
42
123
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
9.5
9
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
9.5
9
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
+∞
9.5
9
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.1
9.2
22
35
GD1AD
NOMESCO Finland
Thorax CT examination
8.8
9.2
19
24
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
39.1
9.1
11
*
2310A
ICD-9 Finland
Carcinoma in situ of respiratory system, Larynx
+∞
8.4
8
*
WX734
NOMESCO Finland
JET-ventilation
+∞
8.4
8
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
8.4
8
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
8.4
8
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
8.4
8
*
DQE00
NOMESCO Finland
Implantation of prosthetic replacement for larynx
+∞
8.4
8
*
DQB30
NOMESCO Finland
Laryngectomy
+∞
8.4
8
*
WX402
NOMESCO Finland
General anaesthesia
4.1
7.7
30
85
JN4BD
NOMESCO Finland
Extensive body CT
5.5
7.6
22
45
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
83.9
7.5
8
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
7.3
7
*
8070/2-C32.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of larynx, NOS
+∞
7.3
7
*
UDQ02
NOMESCO Finland
Direct laryngoscopy
41.9
6.8
8
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
8.7
6.5
13
16
N02AA05
ATC
oxycodone; systemic
3.5
6.4
30
99
A04AA01
ATC
ondansetron; systemic, rectal
19.0
6.3
9
5
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C32.1
ICD-10 Finland
Malignant neoplasm: Supraglottis
+∞
6.3
6
*
C32.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of larynx
+∞
6.3
6
*
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
+∞
6.3
6
*
L02BB03
ATC
bicalutamide; oral
+∞
6.3
6
*
8070/2-C34.3
ICD-O-3
Squamous cell carcinoma in situ, NOS, of lower lobe, lung
+∞
6.3
6
*
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
+∞
6.3
6
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
+∞
6.3
6
*
8140/2-C34.3
ICD-O-3
Adenocarcinoma in situ, NOS, of lower lobe, lung
+∞
6.3
6
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
6.1
77
455
TQW99
NOMESCO Finland
Other minor procedure on skin
6.3
6.0
15
26
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
13
12
11.67
12.11
1.2
1.0
—
—
—
0
0
26
64
4.64
10.13
6.9
1.5
5.4
7.3
ug/l
0.16
26
47
16
27
6.45
9.31
1.3
1.3
—
—
—
0
0
18
41
4.81
7.64
2.5
4.2
—
—
—
0
0
11
8
14.61
6.99
1.5
1.4
14.4
11.4
ug/l
—
11
8
66
373
2.28
5.97
4.3
2.0
2.3
2.3
mmol/l
0.02
58
293
79
481
2.23
5.97
4.9
3.5
—
—
—
0
0
10
17
6.20
5.70
1.7
1.3
—
—
—
0
0
5
0
+∞
5.23
1.2
0.0
—
—
—
0
0
88
582
2.10
5.17
7.3
5.5
1.2
1.2
mmol/l
0.09
79
489
89
592
2.09
5.14
11.2
5.7
4.6
4.6
e9/l
0.00
81
507
11
24
4.84
4.86
1.5
1.3
—
—
—
0
0
10
21
5.00
4.59
1.7
1.3
—
—
—
0
0
79
531
1.94
4.17
6.8
5.3
1.2
1.2
mmol/l
0.30
73
461
8
10
8.34
4.11
1.9
1.4
—
—
—
0
0
46
257
2.10
4.07
3.3
2.0
—
—
—
0
0
11
28
4.14
4.05
1.5
1.4
—
—
—
0
0
8
11
7.58
3.90
1.1
1.3
—
—
—
0
0
64
423
1.84
3.40
2.8
3.0
—
—
—
0
0
7
10
7.25
3.40
1.9
1.4
—
—
—
0
0
8
14
5.94
3.38
1.8
1.3
—
—
—
0
0
5
5
10.25
3.00
2.4
1.4
—
—
—
0
0
5
5
10.25
3.00
2.4
1.4
—
—
—
0
0
24
119
2.19
2.84
1.8
1.6
—
—
—
0
0
32
181
1.95
2.68
2.3
1.6
—
—
—
0
0
5
7
7.32
2.56
2.2
1.3
—
—
—
0
0
23
118
2.10
2.50
1.9
1.7
—
—
—
0
0
32
204
1.71
1.83
3.1
1.7
30.2
29.6
s
0.19
32
194
5
15
3.40
1.53
2.4
1.3
—
—
—
0
0
45
329
1.51
1.47
3.1
2.9
1.4
0.5
e6/l
0.53
36
230
5
16
3.19
1.45
2.2
1.2
—
—
—
0
0
6
22
2.79
1.45
1.0
1.2
—
—
—
0
0
16
90
1.86
1.39
2.5
2.3
56.0
54.2
ml/min/173m2
—
6
35
5
17
3.00
1.37
2.2
1.3
—
—
—
0
0
18
106
1.78
1.36
3.7
6.3
10.1
11.2
mmol/l
0.23
18
100
11
55
2.07
1.30
3.8
2.9
4.1
4.3
pmol/l
0.31
11
45
5
19
2.68
1.22
2.2
1.3
—
—
—
0
0
5
19
2.68
1.22
1.2
1.4
—
—
—
0
0
5
19
2.68
1.22
1.2
1.4
—
—
—
0
0
81
682
1.37
1.18
4.9
3.0
62.7
52.2
u/l
0.45
73
617
17
103
1.73
1.18
1.6
1.9
68.1
66.9
g/l
0.34
17
91
23
157
1.54
1.03
8.3
6.4
3.5
1.5
mmol/l
1.42
18
122
94
823
1.33
1.01
5.0
3.7
15.6
15.1
pmol/l
0.99
85
716
62
511
1.34
1.01
2.4
2.3
—
—
—
0
0
5
23
2.21
0.98
4.0
2.7
3.7
4.3
g/l
—
5
23
54
439
1.34
0.95
1.8
2.2
84.9
76.5
nmol/l
0.77
47
369
20
135
1.55
0.94
6.1
3.0
—
—
—
0
0
9
52
1.77
0.94
1.9
1.2
8.6
10.7
g/l
—
9
46
6
28
2.18
0.92
1.3
1.2
—
—
—
0
0
64
540
1.30
0.86
5.5
5.0
0.0
0.0
estimate
0.00
18
86
25
181
1.45
0.86
4.4
4.8
32.5
32.0
%
0.08
17
117
10
57
1.80
0.85
1.7
1.4
—
—
—
0
0
8
47
1.74
0.82
2.1
1.2
1.3
0.3
g/l
—
8
42
8
47
1.74
0.82
2.1
1.2
41.7
37.0
g/l
—
8
39
63
537
1.28
0.78
4.0
3.7
0.0
0.0
estimate
0.00
17
87
64
548
1.27
0.76
4.0
3.8
0.0
0.0
estimate
0.00
17
81
9
57
1.61
0.72
1.9
1.3
2.9
3.2
g/l
—
9
46
64
551
1.26
0.72
5.5
3.9
52.5
49.5
ng/l
0.05
55
418
5
26
1.95
0.71
2.6
1.8
10.4
12.9
u/ml
—
5
19
9
58
1.58
0.71
1.9
1.3
3.4
3.8
g/l
—
9
45
9
58
1.58
0.71
1.9
1.3
7.1
7.7
g/l
—
9
47
9
58
1.58
0.71
1.9
1.3
—
—
—
0
0
41
337
1.29
0.66
1.4
1.5
20.8
21.4
nmol/l
0.08
33
279
122
1139
1.27
0.65
25.8
13.4
30.2
26.6
mg/l
0.58
111
893
94
853
1.24
0.65
5.1
4.0
15.5
12.9
mm/h
0.72
84
761
37
302
1.29
0.63
4.3
4.0
0.0
0.0
estimate
0.00
14
80
8
51
1.60
0.61
1.8
1.4
—
—
—
0
0
54
464
1.24
0.61
3.5
3.1
743.3
1694.2
ng/l
2.32
47
389
0
21
0.00
0.60
0.0
1.2
—
2.1
—
0
5
12
81
1.52
0.59
1.4
1.5
—
—
—
0
0
35
290
1.26
0.54
2.0
1.8
1184.5
1209.4
nmol/l
0.07
30
213
10
67
1.52
0.51
2.2
2.3
1.4
1.2
%
—
10
67
111
1041
1.20
0.48
6.0
4.5
1.9
2.0
mu/l
0.19
99
909
21
165
1.31
0.48
2.0
2.4
2.2
2.2
g/l
0.02
21
151
49
428
1.21
0.47
4.8
3.9
—
—
—
0
0
29
241
1.25
0.44
2.0
1.7
1.1
1.2
mg/l
0.14
22
189
12
160
0.73
0.42
1.2
1.3
54.1
16.1
u/ml
—
5
49
0
15
0.00
0.41
0.0
1.9
—
23.8
—
0
5
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
5
35
1.44
0.39
2.2
1.2
22.4
38.4
mg/l
—
5
29
5
35
1.44
0.39
2.2
1.2
45.4
58.8
mg/l
—
5
29
24
198
1.25
0.39
2.2
2.8
1.3
1.1
e6/l
0.05
15
109
112
1062
1.17
0.38
24.6
12.8
74.6
72.6
ml/min/173m2
0.49
100
851
20
162
1.27
0.37
6.6
6.1
104.0
104.1
mmol/l
0.02
20
157
12
90
1.36
0.37
1.7
2.2
7.4
15.4
nmol/l
3.27
12
73
9
71
1.28
0.37
1.9
1.5
—
—
—
0
0
110
1152
0.86
0.34
5.3
5.6
2.4
2.5
mmol/l
1.15
100
1036
36
315
1.18
0.34
2.3
2.6
356.9
9422.7
umol/l
1.78
28
267
14
176
0.78
0.34
1.1
1.2
48.0
46.6
iu/ml
—
6
57
26
303
0.83
0.33
2.0
1.9
426.6
24152966.9
pmol/l
0.50
20
236
61
559
1.14
0.32
2.2
2.0
102.7
94.5
pmol/l
0.79
42
298
9
119
0.74
0.28
1.1
1.3
—
—
—
0
0
103
1076
0.89
0.28
4.4
4.5
1.3
1.3
mmol/l
0.11
92
956
107
1113
0.89
0.26
4.7
5.0
1.4
1.4
mmol/l
0.24
97
1000
22
189
1.19
0.26
2.2
3.0
1.6
1.8
e6/l
0.07
13
101
70
657
1.11
0.24
5.9
4.1
2.3
2.1
ug/l
0.11
61
569
5
37
1.36
0.24
1.4
1.2
—
—
—
0
0
5
40
1.26
0.22
5.8
2.1
25.5
24.1
mmol/l
—
5
30
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
48
513
0.91
0.18
5.8
3.9
22.7
24.8
%
0.45
31
257
109
1123
0.91
0.18
4.7
5.0
4.3
4.4
mmol/l
0.12
99
1015
117
1138
1.10
0.17
5.6
5.1
6.3
6.2
mmol/l
0.57
106
1003
122
1202
1.06
0.08
31.3
16.2
87.9
87.3
umol/l
0.05
122
1202
7
83
0.84
0.07
1.4
1.4
—
—
—
0
0
110
1109
0.98
0.02
8.2
6.9
41.6
41.4
mmol/mol
0.09
99
1009
16
167
0.95
0.01
5.1
8.1
—
—
—
0
0
20
204
0.98
0.00
25.7
25.3
1.3
1.3
inr
—
7
26
34
342
0.99
0.00
3.4
2.7
0.9
0.8
ug/l
0.24
26
240
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
0.00
2.4
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
7.5
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
8.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
18.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_EAR_RESP_EXALLC – Carcinoma in situ of middle ear and respiratory system
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).