This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Carcinoma in situ of cervix uteri, exocervix
CD2_INSITU_CERVIX_UTERI_EXOCERVIX_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D06
- Name in latin
- Carcinoma in situ exocervicis (uteri)
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of cervix uteri, exocervix
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of cervix uteri, exocervix
- HSIL lesion of the cervix uteri
- HSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri
- All dysplastic lesions of the cervix uteri, vagina or vulva
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 259 | 259 | - |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | - |
| Median age at first event (years) | 35.48 | 35.48 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 243
- Matched controls
- 2429
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
323.0
243
*
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
498.0
119.6
110
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
35.6
105.2
144
95
ULA02
NOMESCO Finland
Kolposcopy
24.0
100.6
175
235
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
23.7
100.0
175
238
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
287.7
65.7
64
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
25.7
53.9
77
43
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
12.1
53.7
111
157
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
6.8
37.1
116
287
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.8
35.3
69
79
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
21.6
33.1
49
28
ZXC00
NOMESCO Finland
Use of diathermy
33.8
27.2
35
12
N87.1
ICD-10 Finland
Moderate cervical dysplasia
12.5
23.0
42
40
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
126.4
22.0
23
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.6
17.1
41
63
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
159.1
14.6
15
*
LCD10
NOMESCO Finland
Vaginal hysterectomy
7.7
13.7
32
47
H02AB02
ATC
dexamethasone; systemic
26.0
12.6
17
7
115
Kela drug reimbursment
Breast cancer
+∞
12.6
12
*
A04AA02
ATC
granisetron; systemic, transdermal
136.7
12.6
13
*
C539, 6666, 0
ICD-O-3
NA
17.0
12.4
19
12
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
+∞
11.5
11
*
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
+∞
9.4
9
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
9.4
9
*
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
9.4
9
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
9.4
9
*
G01AA10
ATC
clindamycin; vaginal
2.5
9.0
87
441
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
5.1
9.0
28
61
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.8
8.4
60
255
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.4
8
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
8.4
8
*
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
+∞
8.4
8
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
8.4
8
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
4.8
8.4
27
61
XX3DW
NOMESCO Finland
Time consuming IT work
6.5
8.0
20
33
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
7.3
7
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
7.3
7
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
+∞
7.3
7
*
LEB00
NOMESCO Finland
Biopsy of vagina
6.9
7.3
17
26
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.3
7.2
26
66
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
11.4
6.4
11
10
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
+∞
6.3
6
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
6.3
6
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
6.3
6
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
151
3.13
9.28
2.0
1.4
—
—
—
0
0
114
689
2.17
8.35
2.2
1.4
—
—
—
0
0
11
21
5.43
5.57
2.8
1.3
—
—
—
0
0
66
370
2.05
5.55
1.6
1.5
429.3
61128036.3
pmol/l
1.05
53
337
97
706
1.60
3.18
4.2
3.7
36.0
37.2
g/l
1.66
87
659
17
70
2.53
2.94
1.2
1.4
13.7
28.7
u/l
1.55
11
55
35
195
1.92
2.94
3.4
4.2
—
—
—
0
0
29
153
2.01
2.84
2.5
2.1
782.4
2831.9
u/l
—
7
69
85
616
1.57
2.78
2.2
2.7
21.9
17.8
ng/l
0.20
34
284
6
12
5.09
2.41
1.0
1.0
—
—
—
0
0
27
148
1.92
2.39
2.8
2.6
—
—
—
0
0
82
611
1.50
2.31
2.1
2.2
52.0
56.2
u/l
0.61
76
567
35
215
1.73
2.17
3.5
3.5
31.4
32.4
%
0.20
22
159
9
33
2.79
1.95
1.0
1.4
—
—
—
0
0
197
2139
0.67
1.93
7.9
10.3
39.2
39.9
%
0.45
144
1770
8
28
2.91
1.88
1.0
1.1
—
—
—
0
0
8
28
2.91
1.88
1.0
1.1
—
—
—
0
0
8
28
2.91
1.88
1.0
1.1
—
—
—
0
0
123
1021
1.39
1.86
3.3
3.6
6.0
6.3
mmol/l
0.87
114
929
25
150
1.74
1.71
9.4
10.5
1.2
1.2
inr
0.01
12
26
183
1637
1.40
1.68
4.1
3.9
10.9
9.2
mm/h
0.74
168
1546
233
2189
1.64
1.61
10.3
9.2
3.9
3.9
mmol/l
0.06
225
2132
5
127
0.38
1.54
1.2
1.5
—
—
—
0
0
7
27
2.64
1.52
1.0
1.1
—
—
—
0
0
7
27
2.64
1.52
1.0
1.1
—
—
—
0
0
7
27
2.64
1.52
1.0
1.1
—
—
—
0
0
11
52
2.16
1.46
1.0
1.3
—
1.0
—
0
5
68
530
1.38
1.45
3.5
3.2
0.0
0.0
estimate
0.50
35
197
230
2166
1.55
1.43
3.5
3.4
1.3
1.2
mmol/l
0.75
213
2054
99
821
1.33
1.42
4.9
5.0
1.2
1.2
mmol/l
0.06
75
713
18
104
1.79
1.41
1.3
1.6
—
—
—
0
0
13
68
1.96
1.36
2.2
1.6
—
—
—
0
0
231
2185
1.53
1.31
10.3
9.1
139.7
139.7
mmol/l
0.00
223
2131
12
62
1.98
1.30
2.3
1.5
—
—
—
0
0
16
92
1.79
1.28
1.4
1.5
—
—
—
0
0
74
596
1.34
1.28
3.3
1.9
2.4
2.3
mmol/l
0.42
69
534
100
841
1.31
1.27
3.6
2.9
—
—
—
0
0
86
710
1.32
1.25
3.8
4.5
1.2
1.2
mmol/l
0.24
69
653
6
25
2.43
1.25
1.2
1.2
—
—
—
0
0
53
408
1.38
1.22
1.9
1.8
—
—
—
0
0
49
374
1.38
1.18
1.5
1.8
—
—
—
0
0
178
1625
1.30
1.18
3.0
2.8
59.3
35.5
u/l
0.67
167
1565
104
887
1.29
1.18
3.5
3.7
—
—
—
0
0
7
30
2.37
1.13
1.4
1.3
—
—
—
0
0
5
21
2.41
1.09
1.0
1.5
—
—
—
0
0
52
408
1.34
1.06
1.4
1.4
20.3
23.0
nmol/l
0.78
47
358
169
1544
1.27
1.05
8.1
5.0
71.7
72.6
u/l
0.14
162
1441
25
172
1.50
1.04
1.6
1.5
—
—
—
0
0
204
1912
1.32
1.01
4.9
4.5
14.2
14.2
pmol/l
0.10
192
1829
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
234
2244
1.44
0.95
3.8
3.7
1.5
1.6
mmol/l
0.34
221
2140
7
37
1.92
0.94
1.4
1.0
—
—
—
0
0
235
2256
1.45
0.94
3.8
3.8
4.9
4.9
mmol/l
0.20
222
2165
131
1173
1.24
0.93
10.7
7.0
3.9
4.0
e9/l
0.45
120
1019
105
921
1.24
0.89
2.3
2.3
75.4
75.2
nmol/l
0.03
97
855
120
1068
1.23
0.89
3.8
3.0
0.0
0.0
estimate
0.80
37
193
8
139
0.56
0.86
1.5
1.7
—
—
—
0
0
8
140
0.56
0.85
1.5
1.7
—
—
—
0
0
8
45
1.80
0.85
1.1
1.3
—
—
—
0
0
13
200
0.63
0.83
1.3
1.5
—
—
—
0
0
228
2187
1.36
0.83
5.4
5.1
1.8
2.3
mu/l
0.47
210
2089
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
47
569
0.79
0.75
1.6
1.6
1.5
1.4
mmol/l
0.16
38
504
117
1059
1.19
0.69
5.1
4.2
0.0
0.0
estimate
0.50
37
196
5
27
1.87
0.69
6.0
2.3
—
—
—
0
0
5
27
1.87
0.69
1.0
1.0
—
—
—
0
0
235
2276
1.35
0.68
3.9
4.1
2.9
3.0
mmol/l
0.36
222
2166
228
2202
1.30
0.65
11.2
9.1
18.2
17.3
mg/l
0.16
180
1638
50
419
1.24
0.64
1.7
1.9
—
—
—
0
0
5
29
1.74
0.64
1.0
1.1
—
—
—
0
0
243
2369
1.42
0.63
10.4
7.7
23.0
23.7
u/l
0.40
235
2312
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
8
54
1.50
0.58
1.0
1.2
—
—
—
0
0
58
500
1.21
0.58
1.2
1.3
42.1
31.7
iu/ml
0.25
11
177
20
261
0.75
0.57
1.4
1.7
—
—
—
0
0
11
159
0.68
0.56
1.2
1.4
—
—
—
0
0
68
598
1.19
0.55
2.9
2.7
—
—
—
0
0
38
315
1.24
0.55
1.8
1.6
1.3
1.3
%
0.21
31
289
6
38
1.59
0.54
4.0
1.8
1.3
0.9
nmol/l
—
6
33
55
480
1.19
0.48
2.1
2.1
2.8
2.7
mg/l
0.19
48
412
58
510
1.18
0.47
1.2
1.3
2.1
13.0
u/ml
3.39
24
225
9
126
0.70
0.44
2.9
3.6
61.0
73.8
ng/l
—
9
117
51
446
1.18
0.44
2.2
2.4
0.4
0.3
e6/l
0.14
38
320
13
96
1.37
0.42
2.9
2.3
36.4
40.0
u/l
0.36
13
89
15
194
0.76
0.42
1.3
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
10
71
1.42
0.40
1.1
1.2
—
—
—
0
0
5
35
1.44
0.39
1.6
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
8
115
0.69
0.38
1.1
1.7
—
—
—
0
0
10
72
1.40
0.37
4.5
5.2
25.8
24.6
mmol/l
—
10
72
53
473
1.15
0.36
1.5
2.1
309.1
5231.2
umol/l
2.07
45
435
37
321
1.18
0.36
2.2
2.7
1240.1
450.5
ng/l
0.58
24
262
9
124
0.72
0.36
3.1
6.7
5.0
5.2
kpa
—
9
118
6
42
1.44
0.36
1.2
1.2
—
—
—
0
0
13
100
1.32
0.34
1.2
2.0
—
—
—
0
0
220
2148
1.16
0.34
4.1
3.7
5.6
5.7
mmol/l
0.70
208
2034
36
316
1.16
0.31
1.4
1.6
—
—
—
0
0
127
1208
1.10
0.30
2.6
2.9
84.1
65.4
ug/l
1.28
117
1146
8
110
0.72
0.29
1.4
1.8
—
—
—
0
0
239
2353
1.20
0.29
12.8
9.4
67.2
66.5
umol/l
0.23
239
2353
112
1061
1.10
0.28
3.7
3.0
0.0
0.0
estimate
0.00
36
195
8
66
1.22
0.27
1.6
1.7
—
—
—
0
0
10
77
1.31
0.26
2.3
1.6
—
0.0
—
0
8
31
275
1.14
0.24
1.9
1.6
1384.2
1138.5
nmol/l
0.70
24
216
13
157
0.82
0.23
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.9
—
17.2
—
0
13
0
14
0.00
0.20
0.0
1.3
—
8.3
—
0
14
6
49
1.23
0.20
1.0
1.0
—
—
—
0
0
203
1991
1.09
0.20
4.8
4.5
37.1
38.1
mmol/mol
1.48
191
1900
7
90
0.77
0.14
1.6
1.4
—
—
—
0
0
76
730
1.06
0.13
1.7
1.8
93.2
98.3
pmol/l
0.52
50
389
184
1867
0.95
0.11
3.5
3.6
—
—
—
0
0
24
223
1.08
0.09
1.8
1.7
—
—
—
0
0
52
499
1.05
0.09
1.5
1.7
1.0
0.7
mg/l
0.40
42
379
6
55
1.09
0.09
2.2
2.3
153.3
155.0
%
—
6
55
6
58
1.04
0.08
1.0
1.2
3.5
3.7
mmol/l
—
6
53
5
63
0.79
0.08
2.0
1.5
—
—
—
0
0
56
540
1.05
0.08
1.9
1.9
136.6
108.8
u/l
0.22
50
521
6
74
0.81
0.07
1.0
1.1
—
—
—
0
0
6
74
0.81
0.07
1.0
1.1
—
—
—
0
0
210
2087
1.03
0.04
11.0
7.2
88.6
89.2
ml/min/173m2
0.17
180
1672
62
608
1.03
0.03
1.2
1.3
0.6
2.0
u/ml
1.19
30
179
64
630
1.02
0.02
1.5
1.6
—
—
—
0
0
23
237
0.97
0.01
2.4
2.2
2.6
4.5
e6/l
0.89
11
110
30
307
0.97
0.01
2.7
3.0
18.7
389.7
ng/l
0.79
12
173
74
734
1.01
0.00
3.3
2.7
31.8
27.4
u/l
0.56
67
708
19
191
0.99
0.00
4.5
3.5
4.6
4.6
pmol/l
0.03
19
169
27
269
1.00
0.00
1.3
1.2
187.7
148.4
iu/ml
0.19
11
121
25
254
0.98
0.00
2.3
2.0
0.5
1.1
e6/l
1.59
12
128
0
5
0.00
0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
1.2
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
367.6
—
0
5
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
2285.9
—
0
8
9
91
0.99
0.00
2.7
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
68
0.88
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
57.5
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
0.00
1.3
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
6
66
0.91
0.00
3.3
7.5
2.0
1.3
%
—
6
66
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_CERVIX_UTERI_EXOCERVIX_EXALLC – Carcinoma in situ of cervix uteri, exocervix
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).