No definition available.
Leiomyosarcoma, excluding all cancers (controls excluding all cancers)
C3_LEIOMYOSARCOMA_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
314 |
4. Check minimum number of eventsNone |
314 |
5. Include endpointsNone |
314 |
6. Filter based on genotype QC (FinnGen only) |
314 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Leiomyosarcoma, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 314 | 212 | 102 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | 60.36 | 58.51 | 64.23 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 218
- Matched controls
- 2180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
182.3
81.6
81
7
130
Kela drug reimbursment
Malignant tumour
+∞
75.5
68
*
C54.21
ICD-10 Finland
Leiomyosarcoma and myometrium
+∞
74.3
67
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
622.8
51.7
49
*
A03FA01
ATC
metoclopramide; systemic, rectal
12.1
48.7
101
145
L03AA13
ATC
pegfilgrastim; parenteral
+∞
47.7
44
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
47.7
44
*
JN4BD
NOMESCO Finland
Extensive body CT
20.1
45.6
71
51
A04AA01
ATC
ondansetron; systemic, rectal
44.3
44.2
54
16
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
43.2
40
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
40.9
38
*
8890/3-C54.9
ICD-O-3
Leiomyosarcoma, NOS, of corpus uteri
+∞
40.9
38
*
JN4AD
NOMESCO Finland
Body CT examination
27.8
36.5
50
23
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
78.6
35.3
39
6
8890/3-C49.2
ICD-O-3
Leiomyosarcoma, NOS, of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
34.3
32
*
N02AA05
ATC
oxycodone; systemic
8.8
33.9
82
140
A04AA02
ATC
granisetron; systemic, transdermal
390.5
33.9
33
*
Z51.5
ICD-10 Finland
Palliative care
24.6
33.1
47
24
L03AA02
ATC
filgrastim; parenteral
+∞
32.1
30
*
C49.23
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip leiomyosarcoma
+∞
32.1
30
*
B01AB10
ATC
tinzaparin; parenteral
16.7
31.8
52
40
XX3DW
NOMESCO Finland
Time consuming IT work
15.9
31.1
52
42
8890/3-C54.2
ICD-O-3
Leiomyosarcoma, NOS, of myometrium
+∞
31.0
29
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
31.0
29
*
159
Kela drug reimbursment
Pazopanib
+∞
27.7
26
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
27.7
26
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
26.6
25
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
26.6
25
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
25.5
24
*
C54.2
ICD-10 Finland
Malignant neoplasm: Myometrium
+∞
25.5
24
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
26.6
24.8
34
15
C48.03
ICD-10 Finland
Malignant tumor of the retroperitoneal space leiomyosarcoma
+∞
24.4
23
*
L02BG04
ATC
letrozole; oral
140.4
24.1
25
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.9
24.0
101
328
WX302
NOMESCO Finland
Thoracal epidural anesthesy
16.1
23.9
39
29
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
23.3
22
*
B01AB05
ATC
enoxaparin; parenteral
4.5
22.9
110
403
A04AD12
ATC
aprepitant; systemic
+∞
22.3
21
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
24.6
21.5
30
14
L01XE11
ATC
[U] pazopanib; oral
+∞
21.2
20
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
21.2
20
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
11.1
20.7
40
43
KKB10
NOMESCO Finland
Excision of retroperitoneal tumour
219.0
19.9
20
*
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
17.2
19.1
30
20
D70.82
ICD-10 Finland
Drug-induced neutropenia
57.7
18.3
21
*
JN4CD
NOMESCO Finland
Very extensive body CT
29.7
18.2
24
9
WZC30
NOMESCO Finland
Teaching
6.2
17.4
50
100
8890/3-C49.1
ICD-O-3
Leiomyosarcoma, NOS, of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
16.9
16
*
C49.43
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the abdomen leiomyosarcoma
+∞
16.9
16
*
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
+∞
16.9
16
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
183.4
16.7
17
*
LCD00
NOMESCO Finland
Hysterectomy
8.0
16.4
38
56
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
15.8
15
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
15.8
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.8
15.6
81
295
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
12.7
15.3
27
24
WW500
NOMESCO Finland
Blood transfusion
18.2
15.1
23
14
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
34.5
15.1
19
6
ZZR00
NOMESCO Finland
Flap of skin
86.0
14.8
16
*
C49.13
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder leiomyosarcoma
+∞
14.7
14
*
WF002
NOMESCO Finland
Radical radiotherapy
160.2
14.6
15
*
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
12.7
13.7
24
21
A79
ICPC
Malignancy NOS
+∞
13.7
13
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
19.8
13.6
20
11
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
15.1
13.6
22
16
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
13.5
120
630
D39.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Uterus
43.0
13.3
16
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.3
13.2
32
50
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
30.5
13.2
17
6
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
12.6
12
*
8890/3-C49.4
ICD-O-3
Leiomyosarcoma, NOS, of connective, Subcutaneous and other soft tissues of abdomen
+∞
12.6
12
*
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
12.6
12
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
12.6
12
*
8890/3-C48.0
ICD-O-3
Leiomyosarcoma, NOS, of retroperitoneum
+∞
12.6
12
*
C49.29
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip other or unspecified tumor
+∞
12.6
12
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
12.6
12
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
12.6
12
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
12.6
12
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
32.0
11.8
15
5
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
4.7
11.8
42
106
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
45.8
11.0
13
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
29.7
10.9
14
5
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
13.0
10.6
18
15
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.5
10.5
27
46
115
Kela drug reimbursment
Breast cancer
+∞
10.5
10
*
C49.2
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of lower limb, including hip
+∞
10.5
10
*
KAC10
NOMESCO Finland
Total nephrectomy with capsule
+∞
10.5
10
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
10.5
10
*
C49.53
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the pelvis leiomyosarcoma
+∞
10.5
10
*
C54.12
ICD-10 Finland
Adenosquamous carcinoma of the endometrium
+∞
10.5
10
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.4
10.0
26
45
TPH07
NOMESCO Finland
Cathetrisation of artery
4.4
9.7
36
94
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
31.6
9.5
12
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
9.4
9
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
9.4
9
*
343
Kela drug reimbursment
Pazopanib
+∞
9.4
9
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
9.4
9
*
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
9.4
9
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
9.4
9
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
9.4
9
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
9.4
9
*
8890/3-C55.9
ICD-O-3
Leiomyosarcoma, NOS, of uterus, NOS
+∞
9.4
9
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
9.4
9
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.7
9.4
32
77
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
9.3
95
508
WX402
NOMESCO Finland
General anaesthesia
3.5
9.1
45
152
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
19.6
9.0
13
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
9.0
49
176
R50.9
ICD-10 Finland
Fever, unspecified
3.4
9.0
45
153
ZXE20
NOMESCO Finland
More than three and less than five hours
3.5
8.8
43
144
C61
ICD-10 Finland
Malignant neoplasm of prostate
93.5
8.5
9
*
S18
ICPC
Laceration/cut
2.4
8.4
104
607
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
8.4
8
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
8.4
8
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
+∞
8.4
8
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
8.4
8
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
8.4
8
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
8.4
8
*
C49.03
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the head, face and neck Leiomyosarcoma
+∞
8.4
8
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
8.4
8
*
C54.9
ICD-10 Finland
Malignant neoplasm: Corpus uteri, unspecified
+∞
8.4
8
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
8.4
8
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.3
8.0
17
22
ZZA00
NOMESCO Finland
Split skin graft
9.0
8.0
16
19
ZX120
NOMESCO Finland
Intravenous
4.3
7.9
29
75
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.0
7.9
15
16
SPAT1153
SPAT
Removal of sutures
2.4
7.9
83
441
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
5.6
7.8
22
43
JAH00
NOMESCO Finland
Laparotomy
8.5
7.7
16
20
JN3AD
NOMESCO Finland
Abdominal CT examination
4.9
7.5
24
54
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
82.8
7.5
8
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
82.8
7.5
8
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
7.4
49
201
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.3
7.4
27
70
1820C
ICD-9 Finland
Malignant neoplasm of body of uterus, Corpus uteri, except isthmus[SARCOMA MYOMETRI]
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
7.3
7
*
C54.29
ICD-10 Finland
Unspecified uterine sarcoma
+∞
7.3
7
*
C49.83
ICD-10 Finland
Overall malignant tumor of connective tissue and other soft tissue leiomyosarcoma
+∞
7.3
7
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
7.3
7
*
X77
ICPC
Malignant neopl genital female other
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
16.4
7.3
11
7
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.0
7.3
19
34
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.0
7.1
22
48
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
5.0
6.9
21
45
D48.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Retroperitoneum
41.4
6.8
8
*
C03CA01
ATC
furosemide; systemic
2.2
6.8
85
485
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
12.8
6.7
11
9
L02AB02
ATC
medroxyprogesterone; systemic (progestogens)
71.8
6.5
7
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
71.8
6.5
7
*
SPAT1255
SPAT
Intravenous administration of medicine
4.4
6.4
22
54
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.2
6.4
33
115
C48.02
ICD-10 Finland
Malignant tumor of the retroperitoneal space liposarcoma
+∞
6.3
6
*
8890/3-C49.6
ICD-O-3
Leiomyosarcoma, NOS, of connective, Subcutaneous and other soft tissues of trunk, NOS
+∞
6.3
6
*
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
+∞
6.3
6
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
+∞
6.3
6
*
YJ1CD
NOMESCO Finland
Very extensive CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
6.3
6
*
8890/3-C64.9
ICD-O-3
Leiomyosarcoma, NOS, of kidney, NOS
+∞
6.3
6
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
YN1AD
NOMESCO Finland
CT examination of extremities for dose design of radiotherapy
+∞
6.3
6
*
JN6AD
NOMESCO Finland
CT of torso and neck
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
D77
ICPC
Malignant digestive neopl other/NOS
+∞
6.3
6
*
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
27.5
6.3
8
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
7.0
6.1
14
21
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
9.0
6.1
12
14
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.6
6.1
20
47
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
6.0
35
132
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_LEIOMYOSARCOMA_EXALLC – Leiomyosarcoma, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).