Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, excluding all cancers (controls excluding all cancers)

C3_MACROGLOBULINEMIA_EXALLC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C88.0
  • Hospital discharge: ICD-9 2733A
  • Cause of death: ICD-10 C88.0
  • Cause of death: ICD-9 2733A
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9761|9671
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

243

4. Check minimum number of events

None

243

5. Include endpoints

None

243

6. Filter based on genotype QC (FinnGen only)

243

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 243 90 153
Unadjusted period prevalence (%) 0.05 0.03 0.07
Median age at first event (years) 67.64 65.39 68.96

-FinnGen-

Age distribution of first events

0102030506070809001020304050607080AgeIndividuals

-FinnGen-

Year distribution of first events

1970197519801985199520002005201020152020202305101520253035404550556065YearIndividuals

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
125
Matched controls
1249
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
+∞
158.2
116
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
376.5
99.3
89
8
9761/3-C42.0
ICD-O-3
Waldenstrom macroglobulinemia of blood
+∞
98.3
81
*
XW000
NOMESCO Finland
Bone marrow biopsy
106.7
69.9
73
16
A04AA01
ATC
ondansetron; systemic, rectal
145.1
39.4
40
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
179.9
38.1
38
*
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
62.0
34.3
39
9
L03AA02
ATC
filgrastim; parenteral
409.6
32.4
31
*
H02AB02
ATC
dexamethasone; systemic
130.3
29.1
30
*
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
36.8
27.6
35
13
9671/3-C42.1
ICD-O-3
Lymphoplasmacytic lymphoma of bone marrow
+∞
27.1
25
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
279.1
23.5
23
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
264.4
22.4
22
*
JN4BD
NOMESCO Finland
Extensive body CT
16.9
22.2
36
29
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
16.9
21.6
35
28
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
249.9
21.3
21
*
390
Kela drug reimbursment
Ibrutinib
+∞
20.4
19
*
1512
Kela drug reimbursment
Ibrutinib
+∞
20.4
19
*
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
+∞
18.2
17
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
17.1
16
*
L01AA02
ATC
chlorambucil; oral
+∞
17.1
16
*
M04AA01
ATC
allopurinol; systemic
6.0
15.7
50
124
L03AA13
ATC
pegfilgrastim; parenteral
+∞
14.9
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.6
14.3
40
83
1XC02
NOMESCO Finland
NA
+∞
13.8
13
*
L01EL01
ATC
ibrutinib; oral
+∞
13.8
13
*
WW500
NOMESCO Finland
Blood transfusion
14.6
12.7
21
17
J05AB11
ATC
valaciclovir; oral
6.9
12.3
32
59
ZX120
NOMESCO Finland
Intravenous
7.9
12.0
28
44
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
11.6
11
*
C88.9
ICD-10 Finland
Malignant immunoproliferative disease, unspecified
+∞
11.6
11
*
L01XE27
ATC
[U] ibrutinib; oral
+∞
11.6
11
*
A04AA02
ATC
granisetron; systemic, transdermal
131.6
11.6
12
*
R50.9
ICD-10 Finland
Fever, unspecified
6.0
11.6
34
73
C90.0
ICD-10 Finland
Multiple myeloma
+∞
10.6
10
*
L01AA01
ATC
cyclophosphamide; systemic
+∞
10.6
10
*
JN4AD
NOMESCO Finland
Body CT examination
10.6
10.5
20
22
D64.9
ICD-10 Finland
Anaemia, unspecified
5.2
10.4
34
83
J05AB01
ATC
aciclovir; systemic
4.4
10.1
41
125
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
9.6
77
404
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
9.5
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
10.7
9.1
17
18
A03FA01
ATC
metoclopramide; systemic, rectal
4.6
8.6
31
83
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
8.4
8
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
8.4
8
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
8.4
8
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
84.9
7.5
8
*
N08.1*C88.0
ICD-10 Finland
Glomerular disorders in Waldenström's macroglobulinaemia
+∞
7.4
7
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
7.4
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
7.4
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.4
7
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
7.3
24
58
B03XA01
ATC
erythropoietin; parenteral
32.0
7.3
9
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
42.4
6.8
8
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
11.9
6.4
11
10
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
193
100
89.94
278.73
13.2
1.3
14.75
1.14
g/l
29.74
185
92
146
29
124.62
271.46
2.1
1.3
—
—
—
0
0
152
49
81.16
252.52
7.5
1.2
8.23
0.98
ratio
—
7
5
152
50
79.51
251.04
7.6
1.2
117.30
46.50
mg/l
3.02
126
41
152
51
77.92
249.57
7.5
1.2
29.43
35.03
mg/l
0.46
127
43
131
32
87.65
231.34
7.2
1.3
—
—
—
0
0
183
138
50.66
220.27
12.1
1.3
—
—
—
0
0
153
122
32.16
174.68
6.0
1.9
7.77
11.14
g/l
6.21
148
108
89
16
87.19
163.91
1.4
1.1
—
—
—
0
0
119
79
28.56
146.26
10.8
1.1
4.23
3.79
g/l
0.44
74
56
119
79
28.56
146.26
10.8
1.1
6.93
7.67
g/l
2.33
85
60
92
34
42.94
141.72
1.5
1.9
—
—
—
0
0
110
76
25.62
131.65
11.4
1.1
2.92
3.13
g/l
0.87
76
57
107
71
26.14
130.49
11.1
1.1
16.02
10.56
g/l
4.25
85
59
68
18
52.07
113.90
1.9
1.1
—
—
—
0
0
102
9
193.43
103.74
1.7
1.7
3.48
3.49
mg/l
—
97
9
60
21
37.61
92.34
1.1
1.1
—
—
—
0
0
146
262
12.45
90.72
5.5
2.2
1.61
1.71
%
0.48
137
237
127
198
12.34
87.91
5.6
2.3
62.77
65.63
e9/l
0.37
102
156
76
55
19.65
86.68
1.6
1.3
—
—
—
0
0
81
66
17.91
86.65
11.9
1.1
37.93
37.88
g/l
0.02
70
53
90
94
14.62
82.60
2.7
1.8
1.38
1.45
g/l
0.28
80
83
96
127
11.84
74.11
2.0
1.3
—
—
—
0
0
93
122
11.73
72.09
2.0
1.4
—
—
—
0
0
105
164
10.51
70.94
2.0
1.4
—
—
—
0
0
142
314
9.47
70.89
4.3
1.2
1.48
2.92
g/l
5.87
127
179
73
73
13.86
68.12
1.5
1.3
—
—
—
0
0
176
600
8.01
53.85
15.2
5.2
—
—
—
0
0
35
14
29.04
50.59
3.1
1.8
1.41
0.94
e9/l
—
21
9
157
528
6.58
47.05
6.4
2.6
1914.95
11034.07
umol/l
2.12
148
459
206
906
9.37
45.36
14.6
5.0
2.04
1.82
e9/l
0.65
197
786
197
831
8.24
45.35
14.4
5.1
53.55
58.14
%
5.38
192
767
204
890
9.05
45.27
14.6
4.9
0.67
0.61
e9/l
1.93
192
762
74
125
8.07
45.05
7.6
4.0
0.70
0.89
%
0.38
46
32
204
897
8.94
44.64
14.6
4.9
0.04
0.04
e9/l
0.30
192
775
101
238
6.55
44.35
9.4
4.8
1.05
1.01
mmol/l
0.68
94
211
41
0
+∞
44.12
1.7
0.0
14.43
—
titre
—
7
0
207
929
9.29
44.11
15.5
5.0
0.17
0.20
e9/l
2.27
197
803
208
981
8.78
40.56
25.9
5.9
3.46
4.36
e9/l
9.48
195
850
28
11
28.64
40.46
1.4
1.3
—
—
—
0
0
43
5
104.07
40.28
1.4
1.0
—
—
—
0
0
187
815
6.62
39.41
8.9
3.5
32.93
35.10
g/l
4.87
182
751
202
950
7.68
38.76
18.5
5.6
1.22
1.21
mmol/l
0.55
168
816
66
117
7.37
38.02
8.1
4.2
0.02
0.07
%
0.40
41
28
63
110
7.38
36.73
8.3
4.3
0.32
0.33
%
0.02
31
24
143
566
4.71
31.90
14.1
3.2
7.41
7.40
ph
0.88
35
90
183
877
5.40
31.65
16.3
5.2
1.22
1.21
mmol/l
1.41
178
775
92
270
4.87
29.98
4.0
2.4
24.70
23.31
%
0.34
85
236
93
281
4.74
29.11
5.0
3.0
0.80
0.82
mmol/l
0.89
88
258
129
509
4.27
28.03
2.9
2.2
3.07
3.11
mg/l
0.05
113
428
54
111
5.97
26.29
8.3
4.2
0.00
0.04
%
0.49
32
26
30
7
48.63
25.22
3.2
1.4
0.04
0.11
e9/l
—
30
7
25
22
12.55
24.40
1.6
1.2
—
—
—
0
0
26
25
11.53
23.98
2.7
2.2
33.04
33.68
pg
0.28
26
25
153
746
3.84
23.16
4.8
2.7
206.40
135.47
ug/l
1.80
147
680
125
537
3.73
22.93
9.6
3.9
—
—
—
0
0
91
317
3.99
22.78
3.1
1.9
31.59
29.77
s
1.42
85
303
132
604
3.60
21.64
5.2
2.1
2.35
2.35
mmol/l
0.01
116
500
24
5
52.99
20.56
1.6
1.6
—
—
—
0
0
24
5
52.99
20.56
1.6
1.6
3.87
3.20
%
—
24
5
93
351
3.67
20.37
11.3
4.1
—
—
—
0
0
22
21
11.42
20.29
1.3
1.2
—
—
—
0
0
24
6
44.06
19.90
1.3
1.2
—
—
—
0
0
16
11
15.50
17.78
2.1
2.8
37.60
55.00
%
—
5
5
143
768
3.09
16.62
7.0
3.6
—
—
—
0
0
45
116
4.53
16.52
2.8
1.4
2.80
5.36
ug/l
0.52
33
92
18
19
10.15
15.41
10.7
3.9
—
—
—
0
0
61
216
3.44
14.20
1.4
1.2
240.00
574.07
titre
—
5
54
28
55
5.62
14.00
1.5
1.3
—
—
—
0
0
106
520
2.84
13.93
5.3
2.2
—
—
—
0
0
94
436
2.89
13.69
1.9
1.8
1157.77
1193.05
nmol/l
0.12
73
336
92
423
2.89
13.60
6.9
3.7
83.26
84.15
%
0.12
87
415
30
65
5.12
13.47
2.0
2.1
1.60
0.20
g/l
0.51
16
17
21
32
7.09
13.42
4.9
1.6
2.77
4.56
e9/l
2.73
21
32
21
33
6.87
13.05
6.2
2.2
51.33
59.76
%
1.26
21
33
21
34
6.67
12.69
1.5
1.1
—
—
—
0
0
17
7
25.96
12.65
1.6
1.0
—
—
—
0
0
20
31
6.94
12.57
1.1
1.1
—
—
—
0
0
105
545
2.63
11.97
2.1
1.5
21.99
20.82
nmol/l
0.29
93
461
137
809
2.59
11.92
26.7
8.1
0.00
0.00
e9/l
0.52
121
662
86
406
2.73
11.84
15.2
4.4
—
—
—
0
0
198
1416
3.15
11.54
8.2
4.2
54.34
12.45
mm/h
30.36
188
1285
14
16
9.22
11.22
1.4
1.4
—
—
—
0
0
14
16
9.22
11.22
1.4
1.4
—
—
—
0
0
14
16
9.22
11.22
1.4
1.4
—
—
—
0
0
14
16
9.22
11.22
1.4
1.4
—
—
—
0
0
13
14
9.75
10.86
2.6
2.3
—
—
—
0
0
13
14
9.75
10.86
1.2
1.1
—
—
—
0
0
99
524
2.50
10.57
2.5
1.5
—
—
—
0
0
14
18
8.19
10.25
1.9
1.2
—
—
—
0
0
141
891
2.39
9.96
2.6
2.0
95.34
92.11
pmol/l
0.28
89
468
94
503
2.42
9.63
4.7
2.8
—
—
—
0
0
39
133
3.30
9.44
1.4
1.1
—
—
—
0
0
9
0
+∞
9.43
1.7
0.0
—
—
—
0
0
103
579
2.35
9.39
4.9
3.1
12.27
189.13
e6/l
0.89
86
434
65
297
2.62
9.28
2.3
1.7
—
—
—
0
0
114
673
2.31
9.23
5.6
3.6
71.82
101.00
e6/l
0.29
88
472
14
22
6.69
8.62
1.5
1.1
313.00
246.40
u/ml
—
9
10
133
855
2.23
8.57
11.1
10.8
1.26
1.39
inr
1.04
41
237
179
1304
2.42
8.48
5.7
4.1
—
—
—
0
0
74
375
2.40
8.39
4.0
2.7
517.17
555.48
mosm/kgh2o
0.95
60
303
77
401
2.35
8.18
3.7
2.3
3.45
4.48
e6/l
0.76
66
343
10
11
9.44
8.14
1.3
1.3
—
—
—
0
0
94
534
2.24
8.12
4.9
2.8
0.85
0.49
e6/l
0.46
78
386
12
17
7.37
8.07
2.4
1.2
—
—
—
0
0
117
733
2.15
7.84
3.6
3.3
1541.43
1516.61
ng/l
0.03
102
625
72
371
2.34
7.80
4.0
2.2
2.53
2.44
mmol/l
4.73
62
317
13
22
6.19
7.46
1.0
1.0
—
—
—
0
0
16
34
4.97
7.27
1.6
1.1
—
—
—
0
0
75
409
2.21
7.01
1.5
1.3
—
—
—
0
0
38
152
2.78
6.93
15.8
2.6
1.24
1.22
mmol/l
1.43
38
125
44
191
2.59
6.84
11.0
3.3
—
—
—
0
0
74
407
2.18
6.73
2.3
1.7
2.39
1.22
mg/l
0.44
61
319
53
260
2.33
6.31
1.2
1.2
—
—
—
0
0
31
120
2.81
5.99
3.5
2.5
3.32
3.88
e9/l
0.65
18
80
36
151
2.62
5.97
4.6
3.7
93.63
82.25
ng/l
0.22
30
131
14
33
4.44
5.63
1.1
1.9
—
—
—
0
0
46
223
2.31
5.60
1.9
1.7
—
—
—
0
0
35
151
2.54
5.48
2.5
2.0
0.15
0.20
g/l
2.50
29
132
10
18
5.75
5.37
1.3
1.2
—
—
—
0
0
15
39
4.03
5.35
4.3
2.7
—
—
—
0
0
9
8
11.62
5.33
4.0
2.1
2306.67
2618.75
ml
—
9
8
92
594
1.88
5.14
3.6
3.3
—
—
—
0
0
8
6
13.72
5.11
1.4
1.0
—
—
—
0
0
55
298
2.09
5.07
1.4
1.3
71.02
29.66
iu/ml
0.41
12
84
12
28
4.46
4.88
2.8
3.0
—
—
—
0
0
92
607
1.83
4.73
3.6
2.2
60.72
58.44
u/l
0.16
87
557
45
232
2.15
4.70
2.3
1.5
—
—
—
0
0
8
8
10.29
4.55
1.0
1.4
—
—
—
0
0
7
6
11.96
4.30
1.0
1.0
—
—
—
0
0
54
308
1.97
4.29
4.6
2.9
2.05
2.33
e6/l
0.12
36
162
12
32
3.89
4.14
6.4
2.1
—
—
—
0
0
31
145
2.30
4.08
5.8
4.0
7.42
7.38
ph
—
8
13
9
14
6.63
4.02
1.0
1.0
—
—
—
0
0
27
120
2.41
3.98
2.2
2.5
—
—
—
0
0
13
38
3.56
3.96
4.2
2.7
—
—
—
0
0
48
274
1.94
3.78
1.3
1.3
0.80
12.02
u/ml
2.01
13
96
32
159
2.17
3.65
3.9
2.0
30.44
33.28
u/l
0.21
25
129
16
57
2.93
3.60
1.6
1.6
—
—
—
0
0
8
13
6.32
3.53
1.3
1.1
—
—
—
0
0
6
6
10.21
3.51
1.2
1.2
—
—
—
0
0
212
1871
2.04
3.48
45.3
13.9
22.48
24.26
mg/l
0.43
201
1448
8
14
5.87
3.37
2.6
1.8
—
—
—
0
0
6
7
8.75
3.28
1.0
1.3
—
—
—
0
0
8
15
5.47
3.22
2.4
1.1
—
—
—
0
0
99
727
1.61
3.18
3.9
3.6
—
—
—
0
0
31
161
2.06
3.17
1.7
1.9
192.76
129.59
ug/g
0.38
21
123
121
933
1.59
3.17
4.6
3.8
0.00
0.02
estimate
0.50
27
145
87
624
1.61
3.06
5.1
4.2
—
—
—
0
0
118
911
1.57
3.03
4.7
3.8
0.00
0.00
estimate
0.00
28
152
118
918
1.55
2.89
6.4
5.2
0.00
0.00
estimate
0.00
28
149
31
167
1.98
2.88
1.3
1.2
—
—
—
0
0
65
441
1.65
2.83
3.5
4.1
300.02
347.54
ng/l
0.08
54
374
29
155
1.99
2.76
6.4
3.3
—
—
—
0
0
11
37
3.07
2.73
3.2
2.8
—
—
—
0
0
16
67
2.49
2.69
2.1
1.9
—
—
—
0
0
12
43
2.88
2.68
1.5
1.6
12.75
39.76
u/ml
0.67
12
43
7
16
4.47
2.49
1.7
1.2
—
—
—
0
0
7
16
4.47
2.49
2.3
1.2
—
—
—
0
0
31
176
1.87
2.48
11.3
6.1
1.14
1.47
mmol/l
2.01
31
167
8
21
3.90
2.48
1.4
1.2
—
—
—
0
0
138
1136
1.50
2.46
4.2
3.1
60.61
53.25
u/l
0.40
127
1039
5
9
5.64
2.22
1.0
1.2
—
—
—
0
0
185
1639
1.54
2.16
39.3
15.1
34.13
39.37
%
6.19
115
1035
29
169
1.81
2.16
15.4
7.2
—
—
—
0
0
161
1389
1.47
2.12
3.6
3.6
14.84
15.06
pmol/l
0.52
140
1234
110
884
1.45
2.11
5.5
4.1
41.69
46.47
ng/l
0.20
88
675
5
10
5.08
2.08
1.0
1.2
—
—
—
0
0
6
15
4.07
2.05
2.3
1.1
—
—
—
0
0
20
106
1.97
1.97
14.5
9.3
—
—
—
0
0
61
448
1.48
1.83
4.6
3.7
—
—
—
0
0
38
252
1.60
1.80
11.1
6.7
0.89
1.59
mmol/l
0.64
32
195
6
18
3.39
1.75
1.2
1.2
—
—
—
0
0
7
24
2.97
1.73
2.4
1.4
89.71
90.53
%
—
7
24
25
150
1.74
1.71
1.3
1.4
—
—
—
0
0
6
19
3.21
1.67
1.7
1.3
—
—
—
0
0
5
14
3.62
1.62
1.4
1.1
—
—
—
0
0
19
107
1.84
1.60
15.4
8.5
24.11
24.87
mmol/l
0.60
19
94
6
20
3.05
1.59
1.7
1.4
92.92
72.47
pmol/l
—
6
20
27
170
1.66
1.57
2.3
1.6
321.85
365.28
nmol/l
0.69
27
153
15
79
1.96
1.53
1.5
1.3
—
—
—
0
0
6
21
2.90
1.51
1.3
1.0
—
—
—
0
0
11
54
2.09
1.35
4.0
3.6
—
—
—
0
0
6
24
2.54
1.31
2.0
1.1
—
—
—
0
0
5
18
2.81
1.29
1.0
1.1
—
—
nmol/l
—
0
0
5
19
2.66
1.22
1.2
1.0
850.20
572.79
ng/l
—
5
14
5
19
2.66
1.22
1.2
1.0
301.00
267.21
ng/l
—
5
14
27
183
1.53
1.19
4.3
3.0
—
—
—
0
0
6
26
2.34
1.19
3.5
5.0
6.32
6.52
mmol/l
—
6
20
18
110
1.69
1.19
6.9
4.2
—
—
—
0
0
8
39
2.09
1.16
1.3
1.2
—
—
—
0
0
22
143
1.59
1.16
3.3
3.3
—
—
—
0
0
23
154
1.55
1.08
6.3
4.7
—
—
—
0
0
48
607
0.74
1.08
2.6
3.4
—
—
—
0
0
18
115
1.61
1.03
3.4
3.8
—
—
—
0
0
111
972
1.26
1.01
4.4
4.0
1.91
2.08
ug/l
0.20
95
858
57
459
1.32
0.99
1.5
1.8
494.71
422.60
pmol/l
1.04
45
372
30
218
1.43
0.97
6.7
3.2
2.20
2.15
mmol/l
0.02
24
179
186
1736
1.30
0.97
4.4
4.5
1.94
1.96
mu/l
0.08
171
1550
7
37
1.92
0.95
1.1
1.5
—
—
—
0
0
12
70
1.75
0.94
2.3
1.9
—
—
—
0
0
210
1998
1.38
0.92
46.2
16.7
92.33
83.25
umol/l
1.05
210
1998
6
28
2.17
0.92
1.0
1.5
—
—
—
0
0
6
28
2.17
0.92
1.0
1.1
—
—
—
0
0
12
71
1.73
0.90
1.1
1.3
—
—
—
0
0
8
42
1.94
0.89
2.6
2.1
—
—
—
0
0
59
487
1.28
0.86
4.3
3.5
—
—
—
0
0
11
65
1.73
0.84
3.6
4.6
—
—
—
0
0
18
122
1.51
0.83
1.3
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
3.6
—
334.32
—
0
19
205
1955
1.31
0.78
35.4
13.4
—
—
—
0
0
43
527
0.78
0.76
1.5
1.7
1.31
1.35
mmol/l
0.12
38
425
175
1845
0.82
0.69
5.7
6.8
37.90
41.06
mmol/mol
7.67
159
1692
178
1868
0.82
0.63
3.9
5.0
1.39
1.43
mmol/l
0.68
160
1687
14
198
0.69
0.63
1.6
1.5
—
—
—
0
0
78
688
1.20
0.62
6.4
3.3
12266.81
149.46
mg/l
5.42
65
439
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
173
1815
0.84
0.58
3.8
4.5
1.13
1.28
mmol/l
2.50
153
1626
186
1939
0.83
0.58
4.4
5.7
2.33
2.59
mmol/l
4.05
170
1752
6
37
1.64
0.56
1.2
1.2
—
—
—
0
0
181
1888
0.84
0.54
3.9
5.0
4.16
4.45
mmol/l
2.98
165
1714
5
81
0.61
0.46
1.0
1.2
—
99.05
—
0
28
7
50
1.41
0.45
1.1
1.2
—
—
—
0
0
60
536
1.16
0.41
2.9
2.7
0.61
0.76
ug/l
1.36
42
368
8
61
1.32
0.40
1.3
1.1
—
—
—
0
0
57
509
1.16
0.39
5.7
3.9
0.00
0.02
estimate
0.50
23
146
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
149
1418
1.13
0.39
5.7
4.3
—
—
—
0
0
212
2067
1.20
0.38
60.8
20.3
3.95
4.50
e12/l
30.07
206
1990
212
2067
1.20
0.38
60.9
20.4
6.79
6.77
e9/l
0.04
206
1994
5
36
1.40
0.38
3.8
2.4
—
—
—
0
0
5
78
0.63
0.36
1.8
1.5
—
—
—
0
0
12
92
1.32
0.32
5.2
4.6
—
—
—
0
0
7
53
1.33
0.31
6.0
2.5
—
—
—
0
0
17
139
1.24
0.30
1.8
2.4
14.07
14.99
nmol/l
0.24
17
124
37
329
1.15
0.28
40.1
25.6
1.07
1.30
inr
—
6
44
40
445
0.88
0.28
5.4
4.2
1.02
1.02
kg/l
—
8
72
5
38
1.32
0.23
3.8
2.4
4.36
4.11
mmol/l
—
5
38
5
38
1.32
0.23
3.8
2.4
105.60
105.71
mmol/l
—
5
38
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
9
112
0.80
0.20
1.3
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
149
1528
0.94
0.17
50.1
18.5
328.68
332.39
g/l
4.49
149
1513
8
70
1.15
0.16
1.6
1.2
—
—
—
0
0
187
1898
0.94
0.13
4.9
5.1
5.93
6.15
mmol/l
2.22
166
1701
25
229
1.10
0.13
1.9
2.9
8.11
8.38
ug/l
0.02
20
200
13
120
1.09
0.05
4.6
2.2
1.07
1.11
%
0.08
13
120
68
694
0.97
0.04
3.3
3.2
7.03
7.53
mmol/l
0.41
60
565
72
733
0.97
0.04
4.0
4.1
15.54
7.99
mg/mmol
0.52
48
462
16
155
1.03
0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
6.0
—
1484.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
4.4
—
996.80
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
6.7
—
0.71
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
182.80
—
0
7
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
5
56
0.89
0.00
1.6
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_MACROGLOBULINEMIA_EXALLC – Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, excluding all cancers (controls excluding all cancers)

GWS hits: 3

This endpoint is excluded (different definition than used in FinnGen).