No definition available.
Benign neoplasm: Connective and other soft tissue of thorax
CD2_BENIGN_CONNSOFT_THX
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
164 |
4. Check minimum number of eventsNone |
164 |
5. Include endpointsNone |
164 |
6. Filter based on genotype QC (FinnGen only) |
158 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D21
- Name in latin
- Neoplasma benignum textus connectivi/textus mollis thoracis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Connective and other soft tissue of thorax
based on the number of shared cases.
Similar with more cases:
- Other benign neoplasms of connective and other soft tissue
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1115 | 664 | 446 |
| Only index persons | 1009 | 608 | 401 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.52 | 50.31 | 50.70 |
| Only index persons | 50.43 | 50.45 | 50.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 158 | 88 | 70 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 52.96 | 47.29 | 60.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 164
- Matched controls
- 1640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.3
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of thorax
+∞
201.0
149
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.3
39.0
48
58
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
117.2
10.5
11
*
GA1CG
NOMESCO Finland
Extensive MRI of chest
105.9
9.5
10
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
8.4
8.9
19
25
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
9.2
8.0
16
19
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
6.9
7.2
17
27
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
23.6
6.7
9
*
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
15.1
6.5
10
7
2154X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Thorax[THORAXIN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTELE]
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
96
619
2.33
6.48
7.0
6.1
1.21
1.21
mmol/l
0.32
81
529
87
580
2.06
4.94
5.2
5.2
1.20
1.21
mmol/l
0.56
82
527
79
512
2.05
4.81
2.4
2.3
78.96
75.29
nmol/l
0.46
71
460
88
607
1.97
4.37
12.2
12.5
1.22
1.24
inr
0.11
30
177
106
781
2.01
4.33
4.1
4.4
6.78
6.59
mmol/l
0.36
101
721
19
69
2.98
4.18
1.8
3.4
2.64
2.18
mmol/l
0.27
11
53
59
378
1.88
3.48
2.6
3.0
0.13
0.47
e6/l
1.66
41
279
154
1357
3.21
3.47
20.1
15.4
3.96
3.97
mmol/l
0.10
148
1316
145
1242
2.45
3.46
16.7
12.9
82.50
81.73
ml/min/173m2
0.15
123
1000
36
196
2.07
3.37
1.8
2.0
—
—
—
0
0
69
472
1.80
3.26
3.2
3.0
—
—
—
0
0
153
1354
2.94
3.21
20.3
15.4
139.79
139.73
mmol/l
0.14
148
1315
57
370
1.83
3.18
2.9
3.3
1653.96
1084.09
ng/l
0.39
51
305
83
608
1.74
3.04
2.6
2.5
—
—
—
0
0
61
415
1.75
2.86
2.3
2.3
61.71
57.81
u/l
0.24
56
385
40
240
1.88
2.83
1.9
1.7
1075.34
1174.09
nmol/l
0.28
28
186
51
331
1.78
2.80
3.2
2.5
314.40
3424.40
umol/l
1.07
40
286
12
41
3.08
2.68
2.4
2.2
—
—
—
0
0
159
1485
3.32
2.44
26.3
19.9
39.71
40.27
%
0.52
151
1399
159
1485
3.32
2.44
26.6
19.9
4.45
4.50
e12/l
0.55
154
1440
121
1016
1.73
2.44
4.3
3.8
14.80
14.71
pmol/l
0.16
109
923
159
1483
3.37
2.43
26.6
20.0
251.27
248.48
e9/l
0.21
154
1446
37
227
1.81
2.42
4.7
3.3
133.31
137.49
ng/l
0.02
29
167
6
12
5.14
2.42
1.0
1.3
338.67
230.97
u/l
—
6
12
119
997
1.71
2.39
4.8
4.0
11.60
11.74
mm/h
0.04
106
913
5
9
5.69
2.23
1.0
1.3
7.60
12.00
u/l
—
5
9
95
765
1.57
2.13
12.3
9.3
3.91
4.14
e9/l
0.47
83
667
89
713
1.54
1.99
8.5
6.2
16.26
10.99
umol/l
0.59
83
677
120
1029
1.62
1.98
10.0
7.2
92.74
79.41
u/l
1.01
115
957
60
446
1.54
1.86
5.5
3.3
2.35
2.35
mmol/l
0.05
55
399
6
17
3.62
1.85
1.8
1.8
—
—
—
0
0
5
12
4.26
1.83
6.4
4.3
—
—
—
0
0
8
29
2.85
1.81
1.4
1.3
—
—
—
0
0
6
18
3.42
1.76
1.8
1.7
—
—
—
0
0
152
1406
2.11
1.73
21.7
15.7
77.70
77.26
umol/l
0.08
152
1406
5
13
3.93
1.73
1.2
1.0
—
—
—
0
0
26
159
1.75
1.72
5.1
6.7
104.42
104.11
mmol/l
0.10
26
159
146
1338
1.83
1.64
18.9
13.7
20.96
23.39
mg/l
0.44
126
1045
43
306
1.55
1.59
2.5
2.0
2.44
3.08
mg/l
2.42
38
266
65
508
1.46
1.54
2.2
1.9
89.50
93.52
pmol/l
0.33
27
253
5
15
3.40
1.53
1.2
1.1
—
—
—
0
0
48
354
1.50
1.51
4.0
3.7
0.00
0.00
estimate
-0.00
19
118
19
110
1.82
1.50
2.8
2.3
0.22
0.22
g/l
0.01
19
102
78
634
1.44
1.49
4.8
5.0
0.00
0.00
estimate
-0.00
20
124
9
39
2.38
1.45
2.7
1.9
—
—
—
0
0
5
16
3.19
1.45
2.0
1.8
—
—
—
0
0
78
637
1.43
1.44
3.9
3.6
0.00
0.00
estimate
-0.00
22
132
24
152
1.68
1.42
4.7
4.3
28.00
32.77
%
1.09
17
96
17
97
1.84
1.41
2.6
3.9
1.22
1.22
mmol/l
0.03
17
84
135
1227
1.57
1.38
5.7
4.5
10.85
1.94
mu/l
0.50
125
1116
78
641
1.41
1.37
3.9
3.6
0.00
0.00
estimate
-0.00
19
117
5
17
3.00
1.37
2.0
1.8
—
—
—
0
0
5
17
3.00
1.37
2.0
1.8
—
—
—
0
0
5
17
3.00
1.37
2.0
1.8
—
—
—
0
0
35
247
1.53
1.34
1.5
1.6
—
—
—
0
0
32
222
1.55
1.32
2.5
2.6
0.38
0.97
e6/l
1.92
15
124
30
205
1.57
1.32
3.0
2.9
0.85
2.52
e6/l
1.15
13
108
40
292
1.49
1.31
2.6
2.1
—
—
—
0
0
8
34
2.42
1.31
2.1
2.6
23.22
25.50
mmol/l
—
8
34
8
35
2.35
1.29
1.6
1.9
—
—
—
0
0
62
495
1.41
1.27
3.9
3.7
—
—
—
0
0
6
25
2.45
1.25
1.2
1.2
—
—
—
0
0
15
86
1.82
1.24
1.1
1.2
169.93
135.61
iu/ml
—
7
33
40
298
1.45
1.18
1.8
1.7
1.11
1.32
mg/l
0.33
34
238
12
66
1.88
1.12
1.7
1.9
—
—
—
0
0
36
266
1.45
1.11
1.9
1.7
434.35
458.15
pmol/l
0.26
31
223
40
302
1.43
1.10
1.4
1.2
0.99
1.39
u/ml
—
10
89
10
52
1.98
1.08
1.5
1.3
—
—
—
0
0
16
98
1.70
1.08
3.6
2.9
79.17
66.14
ml/min/173m2
—
6
42
19
123
1.62
1.05
4.2
3.6
—
—
—
0
0
102
903
1.34
1.02
3.8
2.9
42.38
46.68
u/l
0.35
97
852
7
35
2.04
1.01
6.9
2.9
45.14
29.30
mg/l
—
7
29
7
35
2.04
1.01
6.9
2.9
31.60
39.08
mg/l
—
7
29
68
569
1.33
1.00
2.7
2.7
106.30
103.27
ug/l
0.08
62
526
0
32
0.00
0.96
0.0
1.6
—
88.43
—
0
32
62
515
1.33
0.95
4.5
3.9
36.77
39.74
ng/l
0.05
40
358
6
29
2.11
0.90
2.0
1.6
—
—
—
0
0
21
147
1.49
0.85
1.6
1.8
—
—
—
0
0
21
147
1.49
0.85
8.3
7.7
—
—
—
0
0
141
1331
1.42
0.80
5.4
4.9
2.80
2.77
mmol/l
0.13
132
1228
137
1291
1.37
0.75
4.9
4.4
6.10
5.89
mmol/l
0.94
124
1190
7
38
1.88
0.74
1.4
1.2
—
—
—
0
0
133
1251
1.33
0.71
4.6
3.9
1.36
1.27
mmol/l
0.84
125
1140
5
28
1.81
0.66
1.0
1.1
—
—
—
0
0
9
137
0.64
0.64
1.6
1.9
—
—
—
0
0
130
1225
1.30
0.64
6.7
5.5
40.84
39.66
mmol/mol
0.76
117
1143
17
123
1.43
0.61
5.8
7.4
123.18
120.75
g/l
0.19
17
118
0
22
0.00
0.60
0.0
1.4
—
—
—
0
0
10
65
1.57
0.57
1.0
1.0
—
—
—
0
0
10
147
0.66
0.56
1.4
2.1
—
—
—
0
0
136
1295
1.29
0.56
5.0
4.3
1.45
1.48
mmol/l
0.29
127
1188
6
38
1.60
0.55
1.2
1.1
—
—
—
0
0
6
39
1.56
0.53
1.0
1.2
—
—
—
0
0
19
146
1.34
0.49
1.6
1.8
—
—
—
0
0
32
265
1.26
0.49
3.1
2.9
0.57
0.70
ug/l
0.45
19
178
7
46
1.54
0.49
4.3
1.4
—
—
—
0
0
136
1303
1.26
0.47
4.9
4.4
4.68
4.66
mmol/l
0.05
127
1209
16
122
1.35
0.44
1.7
1.8
—
—
—
0
0
5
33
1.53
0.41
3.4
2.5
145.00
110.29
ug/min
—
5
19
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
5
34
1.48
0.40
1.8
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
19
152
1.28
0.39
5.5
6.6
1.15
1.21
mmol/l
0.04
14
121
5
80
0.61
0.36
1.0
1.9
—
—
—
0
0
6
43
1.41
0.35
1.8
2.0
—
—
—
0
0
10
73
1.39
0.35
2.0
1.3
—
—
—
0
0
42
373
1.17
0.33
4.3
3.7
4.89
10.07
mg/mmol
1.06
29
234
18
149
1.23
0.29
5.8
6.5
5.21
5.07
kpa
0.26
18
140
18
149
1.23
0.29
5.8
6.5
13.51
11.90
kpa
0.59
18
141
49
448
1.13
0.27
5.0
4.9
3.09
2.66
ug/l
0.12
39
394
5
37
1.36
0.24
1.6
1.4
—
—
—
0
0
5
38
1.33
0.23
1.0
1.1
—
16.54
—
0
5
5
40
1.26
0.22
2.0
1.4
—
—
—
0
0
5
42
1.20
0.21
1.8
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
13.55
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
3.67
—
0
6
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
7
59
1.19
0.18
5.6
3.3
4163.57
2507.71
u/ml
—
7
48
11
94
1.18
0.13
1.9
1.5
—
—
—
0
0
88
854
1.07
0.12
3.1
3.3
—
—
—
0
0
10
86
1.17
0.11
8.7
7.5
24.05
24.80
mmol/l
—
10
80
22
204
1.09
0.09
1.5
1.4
—
—
—
0
0
37
352
1.07
0.09
4.9
4.5
17.32
20.77
%
0.66
16
167
6
72
0.83
0.08
1.5
1.3
—
—
—
0
0
22
221
0.99
0.00
1.2
1.3
12.20
28.02
iu/ml
—
5
75
16
155
1.04
0.00
1.8
2.9
5.19
9.47
umol/l
1.12
16
137
0
7
0.00
-0.00
0.0
1.0
—
111.14
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
136.00
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
61
0.98
-0.00
1.7
1.5
—
—
—
0
0
22
220
1.00
-0.00
1.3
1.3
1.67
5.77
u/ml
—
7
85
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CONNSOFT_THX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_THX | 0.906 [0.64, 1.28] | 0.579 |
| Birth year | 1.0 [0.99, 1.01] | 0.96 |
During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 492 females with CD2_BENIGN_CONNSOFT_THX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_THX | 0.943 [0.68, 1.3] | 0.719 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 322 males with CD2_BENIGN_CONNSOFT_THX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CONNSOFT_THX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.103% | 0.156% |
| 5 | 0.562% | 0.944% |
| 10 | 1.566% | 2.524% |
| 15 | 2.838% | 4.836% |
| 20 | 5.077% | 7.941% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CONNSOFT_THX – Benign neoplasm: Connective and other soft tissue of thorax
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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