This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_VULVA_EXALLC for full statistics.
Malignant neoplasm of vulva
C3_VULVA
vulvar carcinoma: A carcinoma that arises from epithelial cells of the mammalian vulva
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
308 |
4. Check minimum number of eventsNone |
308 |
5. Include endpointsNone |
308 |
6. Filter based on genotype QC (FinnGen only) |
308 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of vulva
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of vulva, excluding all cancers (controls excluding all cancers)
- malignant neoplasm of female genital organs
- malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 308 | 308 | - |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | - |
| Median age at first event (years) | 68.50 | 68.50 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 275
- Matched controls
- 2750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
96.8
161.3
173
47
LFC00
NOMESCO Finland
Partial excision of vulva
+∞
138.6
121
*
ULA02
NOMESCO Finland
Kolposcopy
37.3
133.7
188
150
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
+∞
122.2
108
*
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
+∞
114.8
102
*
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
983.9
78.4
73
*
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
+∞
71.0
65
*
LFD10
NOMESCO Finland
Vulvectomy and excision of regional lymph nodes
+∞
68.7
63
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
103.5
60.0
64
8
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
+∞
49.5
46
*
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
289.2
48.7
48
*
B01AB10
ATC
tinzaparin; parenteral
10.9
43.7
91
119
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
8.2
42.7
110
206
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
15.3
41.4
71
61
C51.00
ICD-10 Finland
Malignant tumor of the labium majus without histology
+∞
39.5
37
*
128
Kela drug reimbursment
Cancers of female genital organs
20.1
35.5
54
33
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
45.1
32.2
39
10
PJA12
NOMESCO Finland
Sentinel node biopsy
6.6
31.5
92
194
ZZR00
NOMESCO Finland
Flap of skin
18.0
29.9
47
31
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
74.6
29.6
33
5
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
116.0
29.3
31
*
LEB00
NOMESCO Finland
Biopsy of vagina
16.0
28.0
46
34
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.2
27.1
149
605
C51.04
ICD-10 Finland
Basal cell carcinoma of labium majus
+∞
26.5
25
*
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
13.6
25.6
45
39
8070/3-C51.0
ICD-O-3
Squamous cell carcinoma, NOS, of labium majus
+∞
25.4
24
*
8070/3-C51.1
ICD-O-3
Squamous cell carcinoma, NOS, of labium minus
+∞
25.4
24
*
D39.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other female genital organs
99.4
25.1
27
*
N76.6
ICD-10 Finland
Ulceration of vulva
31.0
25.1
33
12
LFD00
NOMESCO Finland
Vulvectomy
+∞
24.3
23
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
6.0
23.8
72
153
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.8
23.2
72
158
D07AD01
ATC
clobetasol; topical
4.4
22.1
95
295
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
238.1
21.9
22
*
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
47.6
21.8
26
6
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
8.8
20.4
45
60
C51.09
ICD-10 Finland
Malignant tumor of the labium majus, unspecified histology
+∞
20.0
19
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
10.4
19.7
39
43
8090/3-C51.9
ICD-O-3
Basal cell carcinoma, NOS, of vulva, NOS
+∞
19.0
18
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
8.4
18.3
41
56
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
29.0
18.1
24
9
WF002
NOMESCO Finland
Radical radiotherapy
9.9
17.8
36
41
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
20.3
17.7
26
14
C51.1
ICD-10 Finland
Malignant neoplasm: Labium minus
+∞
16.8
16
*
C77.4
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Inguinal and lower limb lymph nodes
180.4
16.7
17
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
43.0
16.6
20
5
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
13.4
16.3
28
23
8542/3-C51.9
ICD-O-3
Paget disease, extramammary of vulva, NOS
+∞
15.8
15
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
15.8
15
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
90.3
15.7
17
*
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
40.6
15.6
19
5
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.9
14.9
126
622
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
12.9
14.9
26
22
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.1
14.6
41
77
JN4BD
NOMESCO Finland
Extensive body CT
4.1
14.3
61
180
WX306
NOMESCO Finland
Lumbar epidural anesthesy
5.9
14.0
40
77
8720/3-C51.9
ICD-O-3
Malignant melanoma, NOS, of vulva, NOS
+∞
13.7
13
*
C51.21
ICD-10 Finland
Squamous cell carcinoma of the clitoris
+∞
13.7
13
*
XX3DW
NOMESCO Finland
Time consuming IT work
4.0
13.6
58
171
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
6.3
13.4
36
64
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
30.0
13.1
17
6
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
9.4
12.8
26
30
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
33.8
12.7
16
5
8090/3-C51.0
ICD-O-3
Basal cell carcinoma, NOS, of labium majus
+∞
12.6
12
*
C51.89
ICD-10 Finland
Overall malignant tumor of the vulva, unspecified histology
+∞
12.6
12
*
C51.0
ICD-10 Finland
Malignant neoplasm: Labium majus
+∞
12.6
12
*
C51.19
ICD-10 Finland
Adenocarcinoma of the labium minus, unspecified histology
+∞
12.6
12
*
JN4AD
NOMESCO Finland
Body CT examination
4.7
12.6
44
107
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
135.9
12.5
13
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
48.9
12.0
14
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
48.9
12.0
14
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.2
11.3
23
27
LFE10
NOMESCO Finland
Plastic repair of vulva
45.2
11.0
13
*
LFW96
NOMESCO Finland
Other operation on vulva or perineum
+∞
10.5
10
*
C51.13
ICD-10 Finland
Melanoma and labium minus
+∞
10.5
10
*
C51.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of vulva
+∞
10.5
10
*
WX402
NOMESCO Finland
General anaesthesia
3.1
10.2
63
243
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.2
10.0
38
100
B01AB05
ATC
enoxaparin; parenteral
2.3
9.9
125
725
N02AA05
ATC
oxycodone; systemic
2.8
9.8
68
285
X77
ICPC
Malignant neopl genital female other
57.0
9.7
11
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.0
9.6
39
109
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
103.4
9.5
10
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
11.2
9.4
17
16
A46
ICD-10 Finland
Erysipelas
2.9
9.0
59
237
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
19.4
9.0
13
7
L03.3
ICD-10 Finland
Cellulitis of trunk
51.7
8.7
10
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
15.1
8.3
13
9
WX320
NOMESCO Finland
Spinalanesthesy
2.3
8.2
88
463
A04AA01
ATC
ondansetron; systemic, rectal
3.6
8.1
36
110
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
8.1
87
459
H02AB02
ATC
dexamethasone; systemic
3.0
7.9
48
183
A04AA55
ATC
palonosetron, combinations; systemic
6.3
7.5
19
32
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
82.2
7.5
8
*
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
+∞
7.3
7
*
8477
FHL
Vulvectomy
+∞
7.3
7
*
QB4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in groin or genital area (from front)
+∞
7.3
7
*
1844A
ICD-9 Finland
Malignant neoplasm of other and unspecified female genital organs, Vulva, unspecified
+∞
7.3
7
*
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
20.7
7.2
10
5
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
6.9
57
261
ZXC40
NOMESCO Finland
Use of ultrasound
17.2
6.8
10
6
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
17.2
6.8
10
6
ZX090
NOMESCO Finland
Other technic of radiotherapy
5.6
6.6
18
34
C51.03
ICD-10 Finland
Melanoma and labium majus
+∞
6.3
6
*
LFE96
NOMESCO Finland
Other repair of vulva or perineum
+∞
6.3
6
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
6.2
68
358
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.0
6.1
14
21
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
6.1
39
155
D06BB10
ATC
imiquimod; topical
4.3
6.0
21
52
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_VULVA – Malignant neoplasm of vulva
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).