No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D05
- Name in latin
- Carcinoma in situ lobulare mammae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of breast, lobular
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of breast, lobular
- In situ neoplasms
- In situ neoplasms
- Neoplasms
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1248 | 1248 | - |
| Only index persons | 1180 | 1180 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | - |
| Only index persons | 0.04 | 0.04 | - |
| Median age at first event (years) | |||
| Whole population | - | 58.52 | - |
| Only index persons | - | 58.36 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 244 | 244 | - |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | - |
| Median age at first event (years) | 58.32 | 58.32 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 214
- Matched controls
- 2140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D05.0
ICD-10 Finland
Lobular carcinoma in situ
+∞
306.6
213
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
2633.6
138.5
119
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
131.1
112
*
115
Kela drug reimbursment
Breast cancer
+∞
103.8
91
*
HAC20
NOMESCO Finland
Total mastectomy
1048.4
77.4
71
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
129.6
73.9
76
9
HA1AA
NOMESCO Finland
X-ray mammography
39.4
72.0
92
40
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
70.8
64
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
42.4
67.3
84
32
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
62.6
57
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
53.4
49
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
50.0
46
*
HAB99
NOMESCO Finland
Other partial excision of mammary gland
89.5
49.9
54
8
L02BA01
ATC
tamoxifen; oral
+∞
48.8
45
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
48.8
45
*
L02BG04
ATC
letrozole; oral
110.7
48.3
51
6
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
204.9
48.0
48
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
44.3
41
*
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
+∞
43.2
40
*
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
+∞
43.2
40
*
H02AB02
ATC
dexamethasone; systemic
57.1
42.2
49
11
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
36.5
34
*
TQW20
NOMESCO Finland
Tatoe
+∞
36.5
34
*
A04AA02
ATC
granisetron; systemic, transdermal
410.9
36.1
35
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
35.4
33
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
34.3
32
*
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
+∞
34.3
32
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
392.0
33.9
33
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
32.1
30
*
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
+∞
31.0
29
*
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
80.3
30.9
34
5
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
29.9
28
*
N63
ICD-10 Finland
Unspecified lump in breast
12.1
29.3
56
61
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
28.8
27
*
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
321.2
28.5
28
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
27.7
26
*
XX3DW
NOMESCO Finland
Time consuming IT work
14.4
27.7
48
42
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
22.8
26.4
38
20
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
24.4
23
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
24.4
23
*
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
37.0
23.1
29
9
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
+∞
22.3
21
*
X76
ICPC
Malignant neoplasm breast female
+∞
22.3
21
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
22.3
21
*
ZZR10
NOMESCO Finland
Flap of skin and muscle
+∞
21.2
20
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
21.2
20
*
HAE99
NOMESCO Finland
Other reconstruction of breast
231.6
21.0
21
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.2
20.3
100
366
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
18.0
17
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.1
18.0
86
300
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
20.9
17.8
26
14
A03FA01
ATC
metoclopramide; systemic, rectal
4.8
17.3
65
178
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
38.5
17.0
21
6
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
+∞
16.9
16
*
L02BG03
ATC
anastrozole; oral
+∞
16.9
16
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
97.8
16.8
18
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
183.7
16.7
17
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.0
15.8
74
248
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
8.8
14.8
32
42
A04AA55
ATC
palonosetron, combinations; systemic
+∞
14.8
14
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
14.8
14
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
+∞
14.8
14
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
14.8
14
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
14.8
14
*
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
57.3
14.0
16
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
13.7
13
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
13.7
13
*
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
13.7
13
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
13.7
13
*
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
+∞
13.7
13
*
Z31.5
ICD-10 Finland
Genetic counselling
10.8
13.7
26
27
TQB05
NOMESCO Finland
Puncture of skin of trunk
74.4
12.7
14
*
D24
ICD-10 Finland
Benign neoplasm of breast
14.4
12.7
21
16
L02BG06
ATC
exemestane; oral
+∞
12.6
12
*
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
+∞
12.6
12
*
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
137.7
12.6
13
*
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
68.8
11.7
13
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
11.6
11
*
A04AD12
ATC
aprepitant; systemic
+∞
11.6
11
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
45.8
11.0
13
*
HAD99
NOMESCO Finland
Other plastic operation on breast
115.4
10.5
11
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
10.5
10
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
10.5
10
*
HA4MT
NOMESCO Finland
Labeling mammary gland pathology with X-ray guidance
+∞
10.5
10
*
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
+∞
10.5
10
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
10.5
10
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
9.2
10.3
21
25
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
10.2
110
617
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
57.7
9.7
11
*
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
18.6
9.5
14
8
WX402
NOMESCO Finland
General anaesthesia
3.6
9.5
45
147
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
+∞
9.4
9
*
130
Kela drug reimbursment
Malignant tumour
+∞
9.4
9
*
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
+∞
9.4
9
*
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
+∞
9.4
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
9.4
9
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.3
9.2
24
42
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.4
9.1
27
56
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
+∞
8.4
8
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.4
8
*
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
+∞
8.4
8
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
8.4
8
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
+∞
8.4
8
*
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
+∞
8.4
8
*
X21
ICPC
Breast sympt/compl female other
15.3
8.3
13
9
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
34.8
8.1
10
*
JN4BD
NOMESCO Finland
Extensive body CT
5.6
7.8
22
43
A04AA01
ATC
ondansetron; systemic, rectal
8.5
7.7
16
20
B01AB05
ATC
enoxaparin; parenteral
2.4
7.7
77
400
WZC30
NOMESCO Finland
Teaching
3.8
7.7
33
99
ZXA05
NOMESCO Finland
Left side
2.5
7.6
71
355
WF002
NOMESCO Finland
Radical radiotherapy
82.8
7.5
8
*
JN4AD
NOMESCO Finland
Body CT examination
8.9
7.5
15
18
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
7.3
7
*
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
31.2
7.2
9
*
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
41.4
6.8
8
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.7
6.4
12
13
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
6.3
6
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
+∞
6.3
6
*
HAC25
NOMESCO Finland
Radical mastectomy
+∞
6.3
6
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
C50.80
ICD-10 Finland
Overall malignant tumor of the mammary gland, no histological veryfication
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
+∞
6.3
6
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
6.3
6
*
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
+∞
6.3
6
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
6.3
6
*
9703
FHL
Breast resection
27.6
6.3
8
*
ZXA00
NOMESCO Finland
Right side
2.2
6.0
71
393
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
103
5.70
23.15
4.4
1.3
5.0
2.8
ug/l
1.52
38
81
161
1001
2.79
12.98
8.0
3.3
8.9
10.2
umol/l
3.01
153
928
156
1098
2.17
7.63
9.6
6.3
3.6
4.0
e9/l
2.45
136
946
129
857
2.07
7.21
4.0
3.4
—
—
—
0
0
201
1598
2.46
6.88
9.6
5.3
82.4
76.0
u/l
0.70
194
1448
110
727
1.93
5.89
4.1
2.0
2.4
2.4
mmol/l
2.26
99
590
70
411
1.99
5.19
2.3
1.8
—
—
—
0
0
140
1030
1.84
5.14
7.6
4.8
1.2
1.2
mmol/l
0.62
120
875
111
843
1.58
3.07
4.3
3.4
36.5
36.1
g/l
0.41
100
771
16
64
2.61
2.94
2.3
1.6
4.3
5.6
iu/l
—
6
22
120
936
1.56
2.91
5.7
4.4
1.2
1.2
mmol/l
0.52
113
820
10
32
3.22
2.68
1.1
1.3
—
—
—
0
0
188
1656
1.59
2.40
3.9
4.6
13.0
12.8
mm/h
0.07
170
1502
6
13
4.70
2.28
8.3
1.7
9.4
3.6
nmol/l
—
6
13
82
624
1.47
2.08
3.8
2.5
34.1
28.3
u/l
0.44
75
595
237
2269
2.55
2.00
19.5
13.2
70.2
70.1
umol/l
0.02
237
2269
34
513
0.61
1.95
1.4
1.3
0.5
3.0
u/ml
—
6
143
28
169
1.74
1.87
3.5
2.3
1.2
1.2
mmol/l
0.05
28
138
224
2099
1.82
1.81
14.9
11.4
24.4
19.3
mg/l
1.10
181
1586
0
47
0.00
1.72
0.0
1.3
—
—
—
0
0
43
297
1.54
1.71
3.3
2.7
2.9
4.9
e6/l
0.87
21
145
11
51
2.21
1.53
1.1
2.0
95.7
95.1
%
0.02
11
45
19
109
1.81
1.51
1.2
1.4
—
—
—
0
0
61
464
1.42
1.51
1.5
1.6
2.0
0.9
mg/l
0.49
54
353
18
103
1.81
1.45
1.2
1.3
—
—
—
0
0
21
128
1.70
1.38
1.5
1.5
—
—
—
0
0
116
991
1.33
1.37
2.5
2.3
85.0
81.1
nmol/l
0.70
107
866
0
38
0.00
1.35
0.0
2.1
—
—
—
0
0
0
39
0.00
1.35
0.0
1.2
—
21.0
—
0
34
53
411
1.37
1.17
3.6
3.8
89.2
137.4
ng/l
0.41
37
316
201
1882
1.39
1.14
17.0
12.7
37.7
39.5
%
1.55
144
1267
44
333
1.39
1.13
2.7
2.4
1.2
1.4
e6/l
0.17
22
180
54
424
1.35
1.11
2.8
2.1
2.5
2.4
mmol/l
1.52
48
361
65
525
1.32
1.11
3.3
2.9
0.3
0.5
e6/l
0.40
44
393
60
481
1.33
1.07
1.4
1.4
—
—
—
0
0
40
518
0.73
1.04
2.7
2.1
332.0
6071.6
umol/l
2.29
35
423
31
419
0.70
1.04
2.0
1.7
1066.4
1235.1
nmol/l
0.57
24
293
28
198
1.47
1.03
2.5
2.9
—
—
—
0
0
12
199
0.58
1.02
2.4
2.1
316.0
351.9
nmol/l
0.24
12
186
33
242
1.42
1.01
16.7
18.8
1.3
1.2
inr
—
8
40
9
48
1.91
1.01
1.0
1.7
—
—
—
0
0
131
1178
1.24
0.91
3.5
3.6
6.5
6.6
mmol/l
0.30
124
1089
82
947
0.80
0.90
2.0
2.0
100.4
99.0
pmol/l
0.09
36
412
215
2059
1.37
0.83
16.8
10.4
77.1
77.1
ml/min/173m2
0.00
183
1638
77
663
1.24
0.78
2.7
2.0
54.7
54.8
u/l
0.01
68
597
25
185
1.39
0.75
2.4
1.9
27.6
32.3
u/l
0.53
19
150
79
686
1.22
0.74
3.4
3.1
—
—
—
0
0
72
622
1.22
0.71
2.6
2.7
683.0
992.8
ng/l
0.79
62
510
7
118
0.58
0.70
1.1
1.1
—
—
—
0
0
11
69
1.62
0.69
4.9
1.4
1.5
0.3
g/l
0.45
11
62
173
1823
0.82
0.66
5.4
4.4
15.1
14.8
pmol/l
0.60
159
1657
25
191
1.34
0.64
4.6
1.9
6.9
5.4
umol/l
0.37
20
159
6
103
0.57
0.63
1.8
3.3
4.7
5.2
kpa
—
6
97
8
51
1.59
0.61
3.0
1.8
16.3
132.8
u/ml
—
8
43
0
20
0.00
0.60
0.0
1.0
—
547.5
—
0
15
0
20
0.00
0.60
0.0
1.0
—
60.1
—
0
15
0
21
0.00
0.60
0.0
3.6
—
—
—
0
0
12
81
1.51
0.58
5.8
1.4
—
—
—
0
0
11
74
1.51
0.54
3.5
5.4
24.3
24.9
mmol/l
0.35
11
67
39
459
0.82
0.50
1.3
1.3
8.9
14.2
u/ml
0.38
17
173
13
93
1.42
0.49
4.1
4.6
25.9
25.9
mmol/l
0.02
13
93
7
47
1.50
0.48
1.0
1.1
—
—
—
0
0
24
193
1.27
0.45
3.8
4.4
104.3
103.8
mmol/l
0.21
24
187
10
69
1.47
0.45
5.3
1.3
39.4
38.5
g/l
—
10
62
10
69
1.47
0.45
1.8
1.8
932.6
218.8
ug/l
—
10
62
5
31
1.63
0.43
1.0
1.0
—
—
—
0
0
6
92
0.64
0.43
1.2
1.3
—
25.4
—
0
6
50
566
0.85
0.42
2.8
4.3
0.0
0.0
estimate
0.00
15
186
26
313
0.81
0.42
6.2
6.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
48.9
—
0
10
0
15
0.00
0.41
0.0
1.1
—
10.8
—
0
10
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
2.2
—
0
10
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
139
1315
1.13
0.40
4.1
2.8
57.8
43.0
u/l
0.60
122
1195
5
34
1.48
0.40
1.2
1.5
—
—
—
0
0
44
501
0.85
0.40
2.3
2.2
2.5
3.2
mg/l
1.73
36
413
14
106
1.34
0.40
2.5
1.7
—
—
—
0
0
31
263
1.20
0.38
2.5
1.6
27.7
29.4
s
1.75
31
252
5
37
1.36
0.37
1.2
1.3
—
—
—
0
0
5
37
1.36
0.37
1.0
1.5
—
—
—
0
0
11
81
1.37
0.37
5.5
1.4
11.8
11.3
g/l
0.06
11
71
39
340
1.18
0.36
1.6
1.4
—
—
—
0
0
13
99
1.33
0.36
3.2
5.9
0.9
0.7
%
0.98
13
99
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
6
88
0.67
0.33
1.2
1.3
—
4.3
—
0
19
13
101
1.30
0.32
3.2
5.9
1.2
1.4
%
0.39
13
101
50
550
0.89
0.29
1.6
1.5
23.7
23.2
nmol/l
0.10
42
459
113
1072
1.10
0.29
3.0
3.8
0.0
0.0
estimate
0.00
14
179
5
71
0.70
0.26
1.2
1.2
—
60.0
—
0
8
72
671
1.10
0.26
1.6
1.6
1.3
1.4
mmol/l
0.18
52
561
16
191
0.83
0.25
4.1
2.0
67.3
66.8
ml/min/173m2
—
6
76
10
126
0.78
0.25
1.5
1.4
—
—
—
0
0
6
83
0.72
0.24
1.3
1.2
—
—
—
0
0
6
83
0.72
0.24
1.3
1.2
—
—
—
0
0
12
97
1.25
0.23
3.6
2.6
0.2
0.3
e6/l
0.38
12
92
28
315
0.87
0.23
5.1
4.9
32.7
33.6
%
0.22
19
187
43
470
0.90
0.23
1.8
1.7
162857580.9
473.3
pmol/l
0.49
35
368
206
2095
0.89
0.22
5.9
5.9
39.7
39.6
mmol/mol
0.09
190
1926
218
2210
0.87
0.21
4.8
4.8
5.9
5.9
mmol/l
0.01
198
2000
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
9.8
—
0
10
0
12
0.00
0.21
0.0
1.3
—
22.0
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
110
1054
1.08
0.21
3.0
3.9
0.0
0.0
estimate
0.00
14
183
223
2257
0.86
0.21
5.2
5.4
2.8
2.8
mmol/l
0.15
206
2063
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
111
1065
1.08
0.20
4.6
5.1
0.0
0.0
estimate
0.00
14
177
6
48
1.26
0.20
1.2
1.4
—
—
—
0
0
20
174
1.16
0.20
1.6
1.2
183.1
111.1
iu/ml
—
9
70
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
5
68
0.73
0.17
1.2
1.1
—
—
—
0
0
31
283
1.11
0.17
1.9
1.8
—
—
—
0
0
8
69
1.16
0.16
1.4
1.7
—
—
—
0
0
8
70
1.15
0.16
1.5
1.7
—
—
—
0
0
43
461
0.92
0.16
1.2
1.4
30.2
37.3
iu/ml
0.21
15
153
78
815
0.94
0.15
3.2
3.4
26.7
69.9
ng/l
0.47
51
554
11
128
0.85
0.14
3.1
2.2
3.9
4.3
kpa
0.48
11
123
218
2198
0.92
0.10
4.6
4.8
1.6
1.6
mmol/l
0.45
199
2014
79
815
0.95
0.10
2.9
4.0
—
—
—
0
0
21
226
0.92
0.08
2.2
2.3
22.7
22.4
%
0.02
16
183
6
71
0.84
0.07
1.2
1.2
—
13.4
—
0
7
15
137
1.10
0.07
1.1
1.2
60.5
153.9
u/ml
2.05
15
126
90
921
0.96
0.07
2.4
2.7
137.3
91.4
ug/l
0.82
81
832
120
1179
1.04
0.07
2.7
2.6
—
—
—
0
0
210
2114
0.95
0.06
4.1
4.3
1.3
1.3
mmol/l
0.19
191
1914
12
110
1.10
0.05
1.4
1.7
—
—
—
0
0
10
91
1.10
0.04
1.5
1.8
—
—
—
0
0
209
2100
0.97
0.03
6.0
5.4
1.8
2.5
mu/l
0.62
194
1911
17
178
0.95
0.02
1.9
1.7
—
—
—
0
0
11
104
1.06
0.01
1.5
1.4
—
—
—
0
0
20
202
0.99
0.00
2.0
1.8
—
—
—
0
0
10
101
0.99
0.00
1.3
1.7
—
—
—
0
0
14
139
1.01
0.00
2.9
3.9
1.5
1.3
mmol/l
0.14
14
133
221
2213
0.99
0.00
4.7
4.8
4.9
4.9
mmol/l
0.37
205
2037
20
204
0.98
0.00
2.0
1.8
—
—
—
0
0
17
165
1.03
0.00
4.1
1.5
67.6
68.2
g/l
0.09
17
149
12
115
1.05
0.00
4.3
7.7
26.2
25.4
mmol/l
0.32
12
109
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
7
73
0.96
0.00
1.7
3.4
24.6
25.0
mmol/l
—
7
62
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
5
52
0.96
0.00
9.6
1.4
—
1.0
—
0
6
0
6
0.00
0.00
0.0
6.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
6
60
1.00
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
2.1
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_INSITU_BREAST_LOBULAR_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_INSITU_BREAST_LOBULAR_EXALLC | 1.277 [1.05, 1.55] | 0.013 |
| Birth year | 0.998 [0.99, 1.01] | 0.56 |
During the follow-up period (1.1.1998 — 31.12.2019), 162 out of 1098 females with CD2_INSITU_BREAST_LOBULAR_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_INSITU_BREAST_LOBULAR_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.128% | No data |
| 5 | 0.737% | No data |
| 10 | 2.168% | No data |
| 15 | 4.014% | No data |
| 20 | 7.071% | No data |
Relationships between endpoints
↥Index endpoint: CD2_INSITU_BREAST_LOBULAR_EXALLC – Carcinoma in situ of breast, lobular
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data