Purulent endophthalmitis

H7_PURENDOPHTHALMITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H44.0
  • Hospital discharge: ICD-9 3600A
  • Hospital discharge: ICD-8 3660[0-1]
  • Cause of death: ICD-10 H44.0
  • Cause of death: ICD-9 3600A
  • Cause of death: ICD-8 3660[0-1]

2 out of 7 registries used, show all original rules.

225

4. Check minimum number of events

None

225

5. Include endpoints

None

225

6. Filter based on genotype QC (FinnGen only)

222

Control definitions (FinnGen only)

Control exclude
H7_VITREOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
H44
Name in latin
Endophthalmitis purulenta

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1886 976 889
Only index persons 1367 724 643
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 70.38 74.48 66.01
Only index persons 69.64 74.44 64.23

-FinnGen-

Key figures

All Female Male
Number of individuals 222 106 116
Unadjusted period prevalence (%) 0.05 0.04 0.05
Median age at first event (years) 72.35 74.32 70.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
225
Matched controls
2250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H44.0
ICD-10 Finland
Purulent endophthalmitis
+∞
259.5
196
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
51.3
199.8
140
70
CKA10
NOMESCO Finland
Biopsy of vitreous body
+∞
125.0
108
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
51.9
114.8
69
19
WX140
NOMESCO Finland
Parabulbar anesthesy
25.3
113.6
93
61
H44.1
ICD-10 Finland
Other endophthalmitis
+∞
52.1
48
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
11.6
51.3
61
70
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.8
44.8
80
149
H33.0
ICD-10 Finland
Retinal detachment with retinal break
16.1
41.8
38
28
Z96.1
ICD-10 Finland
Presence of intraocular lens
6.1
40.3
106
285
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
13.7
37.9
38
33
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
42.6
34.2
42
12
S01ED51
ATC
timolol, combinations; ophthalmic
7.0
34.1
63
119
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.4
33.3
69
146
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.1
30.0
159
718
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.4
26.9
44
72
H43.1
ICD-10 Finland
Vitreous haemorrhage
+∞
26.6
25
*
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
+∞
25.5
24
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
7.9
24.6
37
55
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
61.0
23.6
27
5
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.5
23.5
75
224
S01ED01
ATC
timolol; ophthalmic
7.1
20.9
34
55
3600A
ICD-9 Finland
Disorders of the globe, Purulent endophthalmitis
+∞
20.1
19
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.6
19.2
148
779
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.4
17.2
143
770
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.6
17.1
73
262
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
25.4
16.8
23
10
H16.0
ICD-10 Finland
Corneal ulcer
6.8
16.3
27
44
CKC12
NOMESCO Finland
Photocoagulation of retina
7.6
16.0
24
35
114
Kela drug reimbursment
Glaucoma
4.0
16.0
54
164
WX142
NOMESCO Finland
Sub-tenon anesthesy
91.6
15.8
17
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
25.6
15.4
21
9
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
36.6
13.7
17
5
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
6.6
13.7
23
38
S01EE01
ATC
latanoprost; ophthalmic
4.2
13.6
40
109
H25.1
ICD-10 Finland
Senile nuclear cataract
2.8
13.4
124
678
H20.1
ICD-10 Finland
Chronic iridocyclitis
53.3
13.0
15
*
H26.2
ICD-10 Finland
Complicated cataract
34.3
12.8
16
5
XCK10
NOMESCO Finland
Photography of fundus of eye
3.6
12.7
49
162
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
137.3
12.6
13
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
28.5
12.2
16
6
S01EA03
ATC
apraclonidine; ophthalmic
22.8
12.2
17
8
WX002
NOMESCO Finland
Sedation and analgesia
3.0
12.1
71
301
H02AB06
ATC
prednisolone; systemic
2.7
11.7
136
815
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
126.2
11.5
12
*
H26.4
ICD-10 Finland
After-cataract
3.4
11.5
49
172
S01EC01
ATC
acetazolamide; systemic
9.4
11.3
23
27
WX704
NOMESCO Finland
Intubation
4.9
11.3
26
58
XCK00
NOMESCO Finland
Perimetry
4.1
11.0
33
91
S01EC04
ATC
brinzolamide; ophthalmic
4.8
10.8
26
60
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
12.1
10.8
19
17
H43.8
ICD-10 Finland
Other disorders of vitreous body
14.2
9.8
16
12
S01EE05
ATC
tafluprost; ophthalmic
5.0
9.8
22
48
H40.0
ICD-10 Finland
Glaucoma suspect
3.6
9.6
34
105
S01EC54
ATC
brinzolamide, combinations; ophthalmic
11.4
9.5
17
16
3643
FHL
Vitrectomy through pars Plana
38.4
9.1
11
*
S01EA05
ATC
brimonidine; ophthalmic
8.5
9.1
19
24
ZX198
NOMESCO Finland
Other local administration
25.2
9.0
12
5
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.1
9.0
41
149
ZXD05
NOMESCO Finland
Urgent procedure
2.4
8.8
85
453
ZXA00
NOMESCO Finland
Right side
2.4
8.7
86
463
H35.36
ICD-10 Finland
Macular cyst
28.8
8.6
11
*
TCK20
NOMESCO Finland
Needle biopsy of vitreous body
+∞
8.4
8
*
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
9.5
8.2
16
18
H34.8
ICD-10 Finland
Other retinal vascular occlusions
7.7
8.1
18
25
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
19.2
7.7
11
6
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
26.0
7.6
10
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
3.2
7.5
32
111
36600
ICD-8 Finland
Other inflammation of uveal tract, Abscessus oculi. Uveitis suppurativa. Panophthalmitis
+∞
7.3
7
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.9
7.2
22
61
Z94.7
ICD-10 Finland
Corneal transplant status
31.1
7.2
9
*
S01BC03
ATC
diclofenac; ophthalmic
9.2
7.2
14
16
S01BA01
ATC
dexamethasone; ophthalmic
4.6
7.1
17
39
H20.8
ICD-10 Finland
Other iridocyclitis
41.3
6.8
8
*
H33.5
ICD-10 Finland
Other retinal detachments
41.3
6.8
8
*
CHC05
NOMESCO Finland
Iridotomy
8.2
6.7
14
18
S01AX11
ATC
[U] ofloxacin
4.4
6.7
17
41
CKD40
NOMESCO Finland
Endophotocoagulation of retina
10.5
6.6
12
12
S01BA04
ATC
prednisolone; ophthalmic
6.5
6.6
16
26
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
71.8
6.5
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.4
61
318
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
18.7
6.3
9
5
XCH00
NOMESCO Finland
Eye pressure measurement
3.6
6.3
21
62
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
6.6
6.3
15
24
H44.5
ICD-10 Finland
Degenerated conditions of globe
+∞
6.3
6
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
6.3
6
*
CKD60
NOMESCO Finland
Anterior vitrectomy
9.0
6.1
12
14
H40.9
ICD-10 Finland
Glaucoma, unspecified
6.3
6.1
15
25
H40.11
ICD-10 Finland
Low pressure glaucoma
6.3
6.1
15
25
H16.9
ICD-10 Finland
Keratitis, unspecified
10.4
6.1
11
11
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.3
6.0
17
34

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
117
265
8.11
55.69
2.3
1.9
—
—
—
0
0
86
207
6.11
36.45
1.7
1.4
—
—
—
0
0
52
212
2.89
9.33
2.1
1.7
—
—
—
0
0
44
224
2.20
4.78
6.3
5.7
2.07
1.48
mmol/l
0.33
31
179
86
563
1.85
4.60
5.8
4.2
—
—
—
0
0
113
808
1.80
4.50
8.3
6.2
—
—
—
0
0
38
187
2.24
4.47
8.2
3.7
1.70
2.21
mmol/l
0.28
30
147
84
556
1.82
4.28
3.4
3.1
6.97
7.04
mmol/l
0.05
72
459
109
780
1.77
4.26
7.0
5.6
0.64
0.63
%
0.05
103
727
63
381
1.91
4.26
4.3
4.6
1.02
1.02
kg/l
0.18
15
49
113
822
1.75
4.14
7.2
5.8
26.19
26.21
%
0.01
107
770
82
547
1.79
4.03
3.5
3.2
93.86
398.38
mg/l
0.86
53
359
86
583
1.77
3.99
4.0
3.8
31.24
8.77
mg/mmol
0.96
56
376
116
856
1.73
3.99
4.5
4.3
0.00
0.01
estimate
0.50
19
189
127
964
1.73
3.92
9.7
6.2
1.20
1.22
mmol/l
2.22
109
816
116
859
1.72
3.92
6.4
5.4
0.64
0.61
e9/l
0.43
100
740
110
803
1.72
3.91
7.1
5.6
2.85
2.82
%
0.04
104
748
110
808
1.71
3.79
7.6
6.0
8.51
8.85
%
0.65
104
756
116
867
1.70
3.73
4.6
4.3
0.00
0.00
estimate
-0.00
17
166
115
858
1.70
3.72
6.2
5.8
0.00
0.00
estimate
-0.00
18
171
117
877
1.70
3.71
6.8
5.3
1.19
1.21
mmol/l
2.33
108
786
115
861
1.69
3.64
6.5
5.4
0.05
0.04
e9/l
1.02
99
745
117
880
1.69
3.64
6.5
5.5
2.13
1.82
e9/l
0.65
102
776
117
881
1.68
3.62
6.7
5.6
0.20
0.19
e9/l
0.07
102
767
13
36
3.77
3.56
1.2
1.1
—
—
—
0
0
109
813
1.66
3.45
6.8
5.5
59.23
58.53
%
0.19
102
763
22
96
2.43
3.39
9.0
6.8
—
—
—
0
0
61
393
1.76
3.29
3.6
4.3
—
—
—
0
0
6
7
8.76
3.28
1.0
1.1
—
—
—
0
0
30
155
2.08
3.13
10.8
6.7
—
—
—
0
0
30
158
2.04
2.98
8.3
3.0
4.52
4.13
kpa
0.47
30
151
70
483
1.65
2.90
4.6
4.6
0.00
0.00
estimate
-0.00
13
167
120
945
1.58
2.87
17.0
17.1
1.35
1.33
inr
0.04
29
271
27
140
2.06
2.79
4.2
3.4
—
—
—
0
0
48
303
1.74
2.75
3.6
3.1
1.27
2.07
e6/l
0.74
26
168
86
634
1.58
2.69
4.4
3.6
—
—
—
0
0
18
80
2.36
2.68
3.6
3.8
—
—
—
0
0
33
187
1.90
2.67
2.0
1.6
—
—
—
0
0
26
136
2.03
2.63
4.1
4.0
1.08
0.58
%
0.33
12
56
89
667
1.55
2.57
5.1
4.0
150.14
97.52
e6/l
0.33
57
494
5
7
7.27
2.56
1.0
1.3
525.60
1235.86
u/ml
—
5
7
120
964
1.52
2.50
6.1
5.9
11.17
11.76
umol/l
0.39
114
908
63
438
1.61
2.50
5.1
6.2
—
—
—
0
0
13
51
2.64
2.49
1.8
1.5
—
—
—
0
0
77
563
1.56
2.46
3.6
2.3
53.33
65.18
u/l
0.71
72
522
125
1016
1.52
2.45
9.3
8.7
4.54
4.29
e9/l
0.49
110
883
151
1282
1.54
2.38
4.6
4.2
17.56
14.30
mm/h
1.13
134
1158
74
543
1.54
2.31
3.6
2.6
—
—
—
0
0
8
23
3.57
2.29
1.3
1.4
—
—
—
0
0
81
608
1.52
2.27
4.8
3.9
7.40
7.40
ph
—
10
112
145
1228
1.51
2.25
5.1
4.4
—
—
—
0
0
15
67
2.33
2.23
1.7
2.2
—
—
—
0
0
28
160
1.86
2.22
4.0
3.9
0.71
0.86
%
0.21
14
72
26
147
1.87
2.13
4.1
4.1
0.27
0.12
%
0.49
11
59
70
516
1.52
2.12
3.9
3.3
—
—
—
0
0
97
765
1.47
2.11
13.7
10.8
0.00
0.00
e9/l
0.51
75
643
73
547
1.50
2.04
4.0
3.3
0.51
0.40
e6/l
0.15
52
425
143
1221
1.47
2.03
5.8
4.7
—
—
—
0
0
5
11
4.62
1.95
1.0
1.4
—
—
—
0
0
77
590
1.46
1.91
4.3
3.5
62.10
154.79
e6/l
0.39
54
460
7
22
3.25
1.89
1.1
1.3
—
—
—
0
0
173
1547
1.51
1.85
5.8
4.8
2.29
2.03
mu/l
1.36
154
1364
145
1256
1.43
1.81
4.7
3.9
14.94
15.18
pmol/l
0.58
122
1094
29
181
1.69
1.74
2.6
2.6
9.69
5.21
ug/l
0.85
22
153
5
13
3.91
1.72
2.0
2.5
—
—
—
0
0
5
14
3.63
1.62
1.4
1.5
—
—
—
0
0
74
579
1.41
1.60
2.7
2.1
177.19
215.46
u/l
0.38
69
540
23
140
1.72
1.52
4.3
4.2
0.00
0.17
%
—
8
54
16
88
1.88
1.45
3.0
2.7
4.06
4.23
pmol/l
0.42
16
73
5
16
3.17
1.44
1.0
1.4
—
—
—
0
0
22
136
1.68
1.38
1.2
1.6
—
—
—
0
0
6
23
2.65
1.37
4.8
4.0
—
—
—
0
0
14
76
1.90
1.33
3.4
1.7
444.07
326.60
ug/l
0.18
14
71
9
44
2.09
1.28
4.9
3.0
—
—
—
0
0
62
488
1.37
1.27
1.9
2.1
3.01
3.26
mg/l
0.27
57
416
11
56
2.01
1.24
1.4
1.6
—
—
—
0
0
10
49
2.09
1.24
3.0
2.1
1.62
1.73
mg/l
—
10
41
17
101
1.74
1.24
1.5
1.4
—
—
—
0
0
99
840
1.32
1.23
6.8
4.2
33.38
34.93
g/l
1.73
89
781
27
182
1.55
1.23
3.5
3.2
66.59
66.28
g/l
0.06
21
162
8
37
2.20
1.22
2.8
2.2
—
—
—
0
0
6
26
2.34
1.19
2.8
1.9
32.83
33.35
pg
—
6
26
178
1648
1.38
1.17
5.4
4.7
4.30
4.48
mmol/l
1.41
156
1486
92
778
1.31
1.16
5.8
4.4
68.21
45.13
ng/l
0.68
68
606
147
1329
1.31
1.10
30.6
22.1
332.41
331.68
g/l
0.44
147
1322
23
154
1.55
1.09
2.0
1.4
—
—
—
0
0
22
146
1.56
1.08
2.1
1.5
—
—
—
0
0
27
188
1.50
1.07
3.0
2.9
56.56
68.48
e9/l
1.22
19
153
186
1742
1.39
1.07
24.4
16.0
—
—
—
0
0
182
1699
1.37
1.07
6.3
5.3
2.39
2.61
mmol/l
2.25
161
1521
176
1636
1.35
1.05
5.3
4.6
1.42
1.45
mmol/l
0.40
153
1466
181
1690
1.36
1.04
24.9
16.4
28.07
24.41
mg/l
0.70
153
1374
59
479
1.31
0.98
3.2
2.9
6999.84
5911.82
umol/l
0.06
50
400
5
23
2.20
0.98
1.8
1.3
—
—
—
0
0
7
37
1.92
0.95
4.3
2.4
—
—
—
0
0
14
218
0.62
0.94
1.0
1.3
—
—
—
0
0
18
119
1.56
0.91
4.4
3.3
—
—
—
0
0
55
447
1.30
0.91
1.7
1.6
1.29
1.33
mmol/l
0.15
45
367
6
29
2.10
0.90
2.7
1.2
—
—
—
0
0
51
411
1.31
0.90
3.6
3.3
526.24
539.28
mosm/kgh2o
0.17
46
353
188
1781
1.34
0.85
28.6
19.6
94.85
82.71
umol/l
1.76
188
1781
36
279
1.35
0.82
4.6
2.3
22.50
21.88
%
0.10
28
245
11
175
0.61
0.82
4.3
4.3
—
—
—
0
0
8
47
1.73
0.81
2.9
2.3
—
—
—
0
0
6
33
1.84
0.79
2.5
3.0
25.50
33.64
umol/l
—
6
28
175
1648
1.28
0.79
5.6
5.1
6.60
6.13
mmol/l
1.62
155
1467
0
27
0.00
0.78
0.0
1.9
—
—
—
0
0
6
34
1.79
0.77
3.5
2.2
—
—
—
0
0
8
136
0.57
0.75
1.5
1.3
—
—
—
0
0
168
1579
1.25
0.74
4.9
4.2
1.31
1.26
mmol/l
0.42
146
1399
9
56
1.63
0.73
14.6
15.5
—
—
—
0
0
7
39
1.82
0.73
4.0
3.2
3.60
4.48
e9/l
—
7
39
7
40
1.77
0.72
4.0
3.6
58.43
60.55
%
—
7
40
171
1613
1.25
0.71
8.0
6.3
44.21
41.07
mmol/mol
2.39
154
1476
27
206
1.35
0.69
4.5
4.0
3.74
64.53
ug/l
0.90
17
167
5
27
1.87
0.69
1.4
1.1
—
—
—
0
0
5
27
1.87
0.69
2.4
1.9
84.46
90.12
%
—
5
27
13
86
1.54
0.67
3.3
3.2
—
—
—
0
0
14
95
1.51
0.66
1.1
1.3
—
—
—
0
0
7
44
1.61
0.65
1.0
1.1
—
—
—
0
0
22
164
1.38
0.65
9.3
3.9
1.21
1.22
mmol/l
0.43
14
143
45
535
0.80
0.63
3.7
3.4
—
—
—
0
0
149
1394
1.20
0.63
9.4
7.1
80.10
80.28
u/l
0.02
140
1293
45
375
1.25
0.62
1.6
1.7
1.21
1.49
mg/l
0.50
35
294
22
166
1.36
0.61
2.1
2.2
172.33
200.12
ug/g
0.09
15
139
8
53
1.53
0.59
1.3
1.2
—
3.54
—
0
5
6
35
1.73
0.58
1.5
1.4
295.00
103.19
pmol/l
—
6
35
56
482
1.22
0.58
4.9
4.0
—
—
—
0
0
77
685
1.19
0.56
3.5
2.6
178.91
144.75
ug/l
0.55
68
605
186
1786
1.24
0.55
13.6
10.9
27.09
24.57
u/l
0.35
177
1708
22
170
1.33
0.54
1.9
2.2
27.24
36.00
u/l
1.02
17
140
15
109
1.40
0.52
4.3
3.0
3.73
6.91
e9/l
—
10
82
6
40
1.51
0.52
1.0
1.2
21.56
18.06
u/l
—
6
34
13
92
1.44
0.52
2.9
2.6
—
—
—
0
0
46
395
1.21
0.49
1.2
1.3
—
—
—
0
0
190
1835
1.23
0.49
35.1
24.3
39.14
39.77
%
0.58
175
1702
37
311
1.23
0.48
1.3
1.5
2.91
2.82
g/l
0.10
23
177
71
636
1.17
0.47
2.9
3.2
2.31
2.35
mmol/l
1.85
60
552
13
94
1.41
0.47
2.3
2.6
—
—
—
0
0
7
50
1.41
0.45
1.7
5.1
—
—
—
0
0
5
31
1.63
0.43
1.0
1.3
—
—
—
0
0
8
60
1.35
0.40
3.3
3.4
—
—
—
0
0
0
18
0.00
0.40
0.0
3.2
—
3.36
—
0
18
86
794
1.13
0.37
2.4
2.1
95.01
94.55
pmol/l
0.03
48
392
5
37
1.36
0.37
1.2
1.5
—
—
—
0
0
20
164
1.24
0.34
2.6
2.5
—
—
—
0
0
23
193
1.21
0.32
1.6
1.3
—
—
—
0
0
7
53
1.33
0.31
1.0
1.2
—
—
—
0
0
7
55
1.28
0.30
7.3
3.1
7.41
7.42
ph
—
7
49
10
77
1.31
0.26
1.4
1.3
—
—
—
0
0
28
245
1.16
0.26
1.3
1.3
—
—
—
0
0
18
152
1.20
0.24
7.4
3.4
149.30
84.58
ng/l
0.72
13
133
53
488
1.11
0.24
1.9
1.6
22.45
20.89
nmol/l
0.31
46
401
5
38
1.32
0.23
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
29.90
—
0
10
0
10
0.00
0.21
0.0
1.1
—
5.75
—
0
5
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
2.66
—
0
6
14
117
1.21
0.21
1.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
4.0
2.9
0.95
0.95
nmol/l
—
6
41
6
49
1.23
0.20
1.0
1.9
—
—
—
0
0
19
167
1.15
0.17
2.2
3.4
—
—
—
0
0
18
159
1.14
0.15
5.4
4.1
—
—
—
0
0
70
668
1.07
0.15
2.1
2.2
—
—
—
0
0
38
403
0.93
0.11
3.1
3.1
1.00
0.77
ug/l
0.56
31
268
5
47
1.07
0.09
2.6
2.8
—
—
—
0
0
5
48
1.04
0.09
8.6
3.1
1.90
2.54
mmol/l
—
5
27
8
75
1.07
0.07
1.0
1.4
—
—
—
0
0
22
233
0.94
0.06
1.3
1.3
1.40
13.70
u/ml
—
5
88
27
259
1.05
0.04
1.3
1.3
65.18
38.57
iu/ml
—
10
97
18
170
1.06
0.04
3.0
2.0
0.18
0.20
g/l
0.83
18
158
70
689
1.02
0.03
4.9
5.2
4.07
2.74
ug/l
0.54
59
611
39
381
1.03
0.02
2.7
3.0
2.44
2.46
mmol/l
0.81
34
331
45
459
0.98
0.02
2.0
1.9
408.76
437.69
pmol/l
0.36
33
373
42
427
0.98
0.01
2.0
1.8
1461.87
1227.70
nmol/l
0.49
31
312
14
139
1.01
0.00
1.5
1.5
—
—
—
0
0
11
113
0.97
0.00
3.3
4.8
—
—
—
0
0
33
335
0.98
0.00
1.3
1.2
0.77
1.18
u/ml
—
7
87
59
593
0.99
0.00
4.9
4.5
—
—
—
0
0
16
164
0.97
0.00
1.4
1.4
—
—
—
0
0
7
74
0.94
0.00
4.9
5.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
1.0
1.2
124.94
183.21
u/ml
—
8
74
0
8
0.00
-0.00
0.0
1.1
—
82.63
—
0
8
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
42.60
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
-0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_PURENDOPHTHALMITIS and mortality.

Females

Parameter HR [95% CI] p-value
H7_PURENDOPHTHALMITIS 1.168 [0.94, 1.45] 0.163
Birth year 0.996 [0.99, 1.0] 0.398

During the follow-up period (1.1.1998 — 31.12.2019), 234 out of 595 females with H7_PURENDOPHTHALMITIS died.

Males

Parameter HR [95% CI] p-value
H7_PURENDOPHTHALMITIS 1.545 [1.18, 2.02] 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 486 males with H7_PURENDOPHTHALMITIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_PURENDOPHTHALMITIS.

N-year risk Females Males
1 0.127% 0.329%
5 0.731% 1.799%
10 1.797% 4.371%
15 3.428% 8.472%
20 5.99% 13.724%

Relationships between endpoints

Index endpoint: H7_PURENDOPHTHALMITIS – Purulent endophthalmitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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