multiple sclerosis: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
224 |
4. Check minimum number of eventsNone |
224 |
5. Include endpointsNone |
224 |
6. Filter based on genotype QC (FinnGen only) |
224 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M35
- Name in latin
- Fibrosclerosis multifocalis
Similar endpoints
↥List of similar endpoints to
Multifocal fibrosclerosis
based on the number of shared cases.
Similar with more cases:
- Other systemic involvement of connective tissue
- Systemic connective tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1805 | 1278 | 511 |
| Only index persons | 1554 | 1106 | 448 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.01 |
| Only index persons | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 72.13 | 72.44 | 71.18 |
| Only index persons | 70.74 | 71.06 | 69.95 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 224 | 151 | 73 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.03 |
| Median age at first event (years) | 63.18 | 61.22 | 67.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 201
- Matched controls
- 2009
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M35.5
ICD-10 Finland
Multifocal fibrosclerosis
+∞
291.0
201
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
191.6
122.9
119
15
H02AB06
ATC
prednisolone; systemic
8.4
38.3
163
679
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
9.9
33.0
73
109
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
29.9
28
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
310.3
27.4
27
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.2
26.7
134
557
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
271.0
24.2
24
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
8.5
22.8
53
81
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
10.9
20.9
41
46
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
8.7
20.4
46
66
P01BA02
ATC
hydroxychloroquine; oral
8.1
20.2
48
75
H02AB07
ATC
prednisone; oral
5.1
18.3
66
176
PAW37
NOMESCO Finland
Biopsy of temporal artery
196.6
17.8
18
*
L88
ICPC
Rheumatoid/seropositive arthritis
12.0
16.9
31
30
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
16.9
16
*
M05BA04
ATC
alendronic acid; oral
4.7
12.6
46
120
M25.5
ICD-10 Finland
Pain in joint
3.2
12.2
83
364
N03AX16
ATC
pregabalin; oral
3.2
11.5
76
323
N02AX02
ATC
tramadol; systemic, rectal
2.8
10.9
109
599
M79.1
ICD-10 Finland
Myalgia
4.1
10.2
42
122
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
9.5
10.1
20
23
L04AX01
ATC
azathioprine; systemic
7.8
9.8
22
31
M13.9
ICD-10 Finland
Arthritis, unspecified
5.2
9.6
30
66
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
9.5
112
661
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
11.5
9.5
17
16
A02BC02
ATC
pantoprazole; systemic
2.8
9.5
155
1097
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.4
9.4
28
58
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
9.1
111
659
M05BA07
ATC
risedronic acid; oral
6.8
8.6
21
34
H04.10
ICD-10 Finland
Dry eye syndrome
4.1
8.5
33
91
M35.7
ICD-10 Finland
Hypermobility syndrome
+∞
8.4
8
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
8.3
108
653
H02AB04
ATC
methylprednisolone; systemic
3.1
7.8
46
175
M01AE02
ATC
naproxen; oral, rectal
2.3
7.6
124
823
J01DB01
ATC
cefalexin; oral
2.9
7.6
172
1357
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.0
7.6
20
36
A07EC01
ATC
sulfasalazine; oral, rectal
4.2
7.3
27
71
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.8
7.3
51
219
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
7.1
39
141
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.6
7.1
24
58
M03BC51
ATC
orphenadrine, combinations; systemic
2.5
7.1
67
338
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
7.0
30
91
J01FA10
ATC
azithromycin; systemic
2.2
6.8
118
792
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.7
6.7
29
88
A46
ICD-10 Finland
Erysipelas
2.9
6.6
42
169
M54.5
ICD-10 Finland
Low back pain
2.3
6.6
81
462
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.3
6.4
23
59
M79.7
ICD-10 Finland
Fibromyalgia
6.7
6.3
15
24
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
6.3
6
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
6.2
85
506
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
6.1
49
223
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
6.1
69
377
R50.9
ICD-10 Finland
Fever, unspecified
2.9
6.1
38
151
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3037522) Nuclear Ab [Titer] in Serum
74
194
5.20
27.70
1.7
1.3
titre
788.3
351.1
1.11
24
45
(42870588) Differential panel, method unspecified - Blood
139
596
4.51
27.32
9.8
4.6
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
84
271
4.36
23.80
1.3
1.3
u/ml
10.4
16.4
0.42
23
99
(3022096) Basophils/100 leukocytes in Blood
159
818
4.25
22.74
12.5
5.1
%
0.5
0.6
1.78
153
750
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
85
290
4.11
22.10
1.5
1.2
iu/ml
36.3
42.1
0.18
27
94
(3006315) Basophils [#/volume] in Blood
165
888
4.26
21.70
12.3
5.0
e9/l
0.0
0.0
0.21
149
761
(3006504) Eosinophils/100 leukocytes in Blood
159
836
4.11
21.60
12.6
5.1
%
2.4
2.7
1.14
153
766
(3001604) Monocytes [#/volume] in Blood
164
882
4.21
21.52
12.3
5.0
e9/l
0.6
0.6
1.01
148
754
(3019069) Monocytes/100 leukocytes in Blood
159
841
4.07
21.29
12.8
5.4
%
8.5
8.6
0.15
153
778
(3013115) Eosinophils [#/volume] in Blood
167
915
4.24
21.19
12.4
5.3
e9/l
0.2
0.2
0.64
151
796
(3002030) Lymphocytes/100 leukocytes in Blood
159
854
3.97
20.50
13.0
5.3
%
25.4
27.0
0.97
152
786
(3018010) Neutrophils/100 leukocytes in Blood
158
846
3.94
20.45
12.5
5.1
%
60.8
58.1
1.72
152
785
(3019198) Lymphocytes [#/volume] in Blood
164
904
4.04
20.23
12.7
5.0
e9/l
1.8
1.8
0.36
147
794
(4062490)
16
12
14.28
16.97
3.5
1.6
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
115
576
3.05
15.13
3.3
2.0
u/l
402.9
215.3
0.32
102
538
(3013650) Neutrophils [#/volume] in Blood by Automated count
168
1059
3.35
14.35
14.3
8.8
e9/l
4.6
4.2
1.64
152
919
(3037467) Urinalysis macro (dipstick) panel - Urine
184
1255
3.61
13.16
7.3
4.5
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
147
909
2.80
12.06
4.8
4.0
estimate
0.0
0.0
0.00
39
181
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
152
957
2.83
12.03
7.7
6.1
mmol/l
1.2
1.2
0.41
134
799
(3013707) Erythrocyte sedimentation rate by Westergren method
191
1368
3.69
11.87
13.0
3.8
mm/h
14.1
13.3
0.30
178
1241
(3035350) Ketones [Presence] in Urine by Test strip
144
893
2.72
11.55
4.7
4.0
estimate
0.0
0.0
0.00
34
191
(3021601) Nitrite [Presence] in Urine by Test strip
144
901
2.68
11.21
6.1
5.3
estimate
0.0
0.0
0.00
38
186
(3020630) Protein [Mass/volume] in Serum or Plasma
45
152
3.45
11.19
1.8
2.9
g/l
65.9
66.4
0.15
40
133
(3025159) Blasts/100 leukocytes in Blood
41
132
3.58
10.96
8.9
4.2
%
0.0
0.0
0.00
11
37
(3026493) Urate [Moles/volume] in Serum or Plasma
92
469
2.63
10.88
2.8
2.7
umol/l
3835.1
10470.3
0.83
81
386
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
23
51
4.91
10.03
1.5
1.4
iu/ml
0.0
0.0
—
5
12
(3002179) Metamyelocytes/100 leukocytes in Blood
39
129
3.45
9.97
6.9
4.0
%
0.1
0.6
—
7
32
(3005719) IgG [Mass/volume] in Serum or Plasma
38
124
3.49
9.92
4.8
3.0
g/l
10.5
10.0
0.32
38
110
(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
27
70
4.25
9.73
1.4
2.5
g/l
3.4
3.1
0.41
20
52
(3045414) Leukocytes [Presence] in Urine
27
71
4.19
9.55
2.2
2.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
39
133
3.34
9.49
1.6
2.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
125
775
2.39
9.28
3.3
2.2
nmol/l
83.2
77.8
1.56
119
673
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
17
31
5.85
9.12
1.1
1.2
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
136
881
2.38
9.05
6.8
5.6
mmol/l
1.2
1.2
0.14
126
796
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
24
62
4.22
8.67
1.3
2.6
g/l
37.3
37.8
0.14
19
49
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
27
77
3.85
8.55
1.4
2.4
g/l
3.5
3.8
0.51
20
50
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
27
77
3.85
8.55
1.4
2.4
—
—
—
0
0
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
27
77
3.85
8.55
1.4
2.4
g/l
7.4
7.4
0.03
21
53
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
19
41
4.97
8.52
1.9
1.3
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
131
851
2.30
8.44
4.9
4.0
g/l
34.8
34.9
0.04
120
790
(3021440) Promyelocytes/100 leukocytes in Blood
38
137
3.14
8.41
9.7
4.1
%
0.0
0.2
—
9
41
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
189
1448
2.95
8.41
12.0
6.9
u/l
76.8
79.9
0.34
179
1343
(3018095) Leukocytes [#/volume] in Urine
110
672
2.25
8.13
5.6
3.8
e6/l
116.8
86.1
0.25
88
490
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
61
290
2.52
8.00
3.2
2.8
e6/l
3.2
2.7
0.15
42
152
(3028026) IgM [Mass/volume] in Serum or Plasma
32
107
3.32
8.00
2.2
1.7
g/l
1.1
1.5
0.71
32
93
(3045424) Erythrocytes [Presence] in Urine
14
24
6.16
7.95
1.9
1.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
49
210
2.71
7.93
1.6
1.7
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
82
448
2.31
7.88
5.2
3.5
%
90.7
89.7
0.11
82
438
(40758558) Short blood count panel - Blood
83
457
2.30
7.82
8.5
6.7
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
13
21
6.51
7.80
1.2
1.8
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
99
587
2.23
7.79
4.3
3.3
e6/l
44.1
186.7
0.68
85
454
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
57
266
2.53
7.76
2.8
2.3
%
22.2
21.4
0.17
52
235
(3017181) Myelocytes/100 leukocytes in Blood
39
150
2.94
7.70
9.5
3.9
%
0.6
1.0
—
9
48
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
104
632
2.21
7.67
3.2
3.3
ng/l
1615.0
1744.3
0.12
90
537
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
14
25
5.91
7.64
1.4
1.1
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
39
151
2.92
7.61
1.4
1.6
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
86
486
2.25
7.57
2.5
2.1
mg/l
3.2
3.3
0.23
68
412
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
33
118
3.11
7.38
1.5
1.7
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
122
799
2.16
7.35
16.6
10.3
e9/l
0.0
0.0
0.41
109
642
(3021788) Differential panel - Synovial fluid
15
30
5.29
7.29
1.7
1.7
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
120
786
2.13
7.17
2.5
2.0
pmol/l
90.8
95.4
0.57
63
378
(3011397) Hemoglobin [Presence] in Urine by Test strip
74
401
2.26
7.14
3.9
3.9
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
29
99
3.22
7.00
1.2
1.4
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
17
40
4.52
6.88
1.3
1.7
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
37
151
2.74
6.52
4.1
3.2
ng/l
77.7
87.6
0.47
32
130
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
16
39
4.34
6.20
1.4
1.4
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
103
663
2.02
6.19
2.7
3.1
mmol/l
2.4
2.4
0.02
87
577
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
66
361
2.17
6.11
4.8
3.6
ng/l
74.9
150.9
0.58
53
293
(46235355) HIV 1 and 2 tests - Meaningful Use set
45
210
2.43
6.03
1.6
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
64
348
2.17
6.00
2.0
1.4
g/l
2.3
2.6
0.59
42
203
(3027945) Reticulocytes/100 erythrocytes in Blood
47
225
2.38
5.95
2.9
2.9
%
1.4
1.8
3.10
41
203
(3000850) Epithelial cells [#/volume] in Urine
73
421
2.09
5.86
3.5
2.7
e6/l
3.6
4.9
0.82
62
375
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
138
1004
1.98
5.66
5.4
5.8
umol/l
9.7
10.9
1.67
127
944
(3023368) Bacteria identified in Blood by Culture
87
543
1.98
5.57
5.9
4.0
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
40
184
2.43
5.51
1.5
1.6
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
176
1405
2.18
5.46
5.2
4.1
pmol/l
15.3
14.9
0.96
157
1244
(3032080) INR in Blood by Coagulation assay
116
805
1.91
5.38
10.3
9.2
inr
1.3
1.3
0.09
28
246
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
103
689
1.92
5.33
4.6
3.1
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
92
594
1.93
5.28
2.8
2.3
u/l
69.6
55.5
0.89
83
539
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
59
327
2.09
5.19
1.9
1.8
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
10
19
5.46
5.09
2.9
2.8
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
112
779
1.88
5.06
3.4
2.6
ug/l
110.0
121.6
0.33
101
706
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
21
72
3.11
5.02
1.9
2.0
u/l
33.5
39.4
0.76
21
62
(36304419) Bacteria [Presence] in Urine
82
517
1.92
5.00
4.2
3.0
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
66
387
2.00
4.96
2.9
3.0
mmol/l
2.5
2.5
0.05
53
341
(40768797) Stomach Pathology biopsy report
49
259
2.14
4.85
1.2
1.2
—
—
—
0
0
(3026782) Osmolality of Urine
68
406
1.97
4.85
3.5
2.9
mosm/kgh2o
515.7
532.7
0.36
55
348
(3030467) Casts [#/volume] in Urine by Automated count
84
539
1.89
4.83
4.3
3.0
e6/l
0.2
0.6
2.11
71
404
(3018418) pH of Serum or Plasma
92
611
1.86
4.73
4.9
4.1
ph
7.4
7.4
0.10
14
122
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
15
43
3.67
4.70
1.1
1.1
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
145
1115
1.85
4.57
6.0
4.5
mmol/l
6.8
6.7
0.18
139
1033
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
207
1814
2.86
4.49
30.7
15.0
mg/l
18.1
23.5
2.25
181
1450
(3026008) Bacteria identified in Urine by Culture
95
652
1.79
4.30
3.5
3.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
51
286
2.01
4.29
2.1
2.0
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
9
13
7.16
4.20
1.3
1.1
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
9
13
7.16
4.20
1.3
1.1
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
9
13
7.16
4.20
1.3
1.1
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
9
13
7.16
4.20
1.3
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
9
13
7.16
4.20
1.3
1.1
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
9
13
7.16
4.20
1.3
1.1
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
16
52
3.24
4.17
1.1
1.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
54
312
1.96
4.17
3.3
2.6
e6/l
1.1
1.3
0.13
35
172
(3012095) Magnesium [Moles/volume] in Serum or Plasma
51
290
1.98
4.12
3.1
3.2
mmol/l
0.8
0.8
0.23
46
271
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
23
94
2.61
4.03
2.7
2.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
42
225
2.07
3.99
1.9
1.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
62
382
1.86
3.93
10.2
4.9
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
65
407
1.84
3.92
1.8
1.6
mg/l
1.5
1.3
0.14
52
326
(3019309) Folate [Moles/volume] in Red Blood Cells
65
410
1.82
3.82
1.8
1.7
nmol/l
1125.2
1221.7
0.35
53
304
(3020779) Urea [Moles/volume] in Serum or Plasma
30
144
2.25
3.74
5.8
5.6
mmol/l
9.7
10.0
0.13
30
134
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
42
231
2.01
3.71
1.9
1.8
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
13
40
3.39
3.68
1.1
1.1
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
32
160
2.17
3.62
2.0
2.7
e9/l
61.3
71.3
1.14
24
127
(40768804) Tissue Pathology biopsy report
102
742
1.69
3.60
2.3
2.2
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
14
46
3.18
3.59
1.5
1.5
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
7
9
7.98
3.58
1.4
1.3
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
9
17
5.47
3.55
1.1
1.2
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
191
1664
2.00
3.42
6.7
4.9
mu/l
1.7
2.0
4.02
175
1484
(3044640) Blood type and Crossmatch panel - Blood
83
580
1.68
3.35
2.6
2.3
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
60
383
1.77
3.35
1.4
1.2
u/ml
1.2
1.8
0.43
12
108
(36660697) Celiac disease serology panel - Serum
27
130
2.22
3.35
1.1
1.1
—
—
—
0
0
(3002256) Pathology report gross observation
40
226
1.94
3.27
1.3
1.3
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
33
174
2.05
3.26
2.8
2.3
u/l
29.3
29.0
0.04
26
144
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
10
28
3.69
3.23
1.1
1.0
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
8
15
5.49
3.22
1.0
1.1
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
7
11
6.53
3.21
1.6
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
65
430
1.72
3.19
2.4
2.2
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
8
16
5.14
3.08
1.1
1.0
—
—
—
0
0
(3019225) pH of Specimen
32
172
2.00
3.01
4.8
4.0
—
—
—
0
0
(3006922) Hepatitis E virus Ab [Presence] in Serum
5
5
10.18
2.99
1.2
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
124
979
1.60
2.97
2.9
2.7
—
—
—
0
0
(3013512) EKG study
80
569
1.63
2.96
4.9
4.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
37
213
1.88
2.86
1.7
1.3
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
69
479
1.64
2.78
2.0
1.5
nmol/l
22.2
21.4
0.16
59
393
(3023410) Appearance of Cerebral spinal fluid
7
14
5.12
2.75
1.3
1.1
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
135
1102
1.57
2.70
3.2
3.0
u/l
42.9
49.5
0.80
125
1021
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
27
142
2.02
2.70
2.0
1.5
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
73
520
1.60
2.64
5.3
4.2
estimate
0.0
0.0
0.00
38
178
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
96
729
1.55
2.63
4.6
4.1
—
—
—
0
0
(3008898) HLA-B27 [Presence]
12
44
2.83
2.59
1.2
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
25
130
2.04
2.57
3.3
2.8
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
22
109
2.13
2.56
4.2
3.4
mmol/l
1.7
2.5
0.49
15
86
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
5
7
7.27
2.56
1.2
1.3
u/ml
593.4
1057.9
—
5
7
(4027681)
6
11
5.57
2.56
1.2
1.2
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
6
11
5.57
2.56
1.0
1.0
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
16
69
2.42
2.55
1.0
1.1
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
15
63
2.48
2.52
4.3
3.0
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
11
39
2.91
2.51
2.8
2.2
—
—
—
0
0
(3004809) Band form neutrophils/100 leukocytes in Blood
9
26
3.56
2.51
2.0
3.3
%
1.9
2.0
—
9
21
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
13
51
2.64
2.49
1.6
1.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
72
518
1.57
2.47
4.7
3.7
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
6
12
5.10
2.41
1.0
1.1
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
204
1872
2.01
2.35
26.6
18.0
mmol/l
139.8
139.7
0.13
196
1816
(3000570) Elastase.pancreatic [Mass/mass] in Stool
14
59
2.46
2.34
1.9
1.5
ug/g
235.5
275.5
—
8
36
(3030905) Polymorphonuclear cells [#/volume] in Blood
9
28
3.30
2.33
8.9
2.5
e9/l
5.5
5.4
—
9
28
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
6
13
4.71
2.28
1.0
1.0
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
107
851
1.49
2.28
5.2
4.0
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
28
159
1.87
2.26
2.7
2.9
ng/l
177.9
262.8
0.63
23
143
(3023103) Potassium [Moles/volume] in Serum or Plasma
204
1877
1.97
2.25
26.9
18.1
mmol/l
4.0
4.0
0.85
195
1818
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
9
29
3.19
2.25
9.0
3.1
%
61.0
62.9
—
9
29
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
5
9
5.65
2.22
1.0
1.6
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
11
42
2.70
2.22
1.5
1.3
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
11
42
2.70
2.22
1.5
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
17
81
2.19
2.19
4.8
3.5
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
13
55
2.45
2.16
1.6
1.6
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
30
177
1.80
2.16
2.2
2.5
ug/l
7.7
4.9
0.45
22
151
(4010399)
25
139
1.90
2.15
1.2
1.4
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
10
37
2.78
2.13
1.2
1.5
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
14
62
2.34
2.12
1.9
5.3
ratio
1.2
3.1
—
5
8
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
8
25
3.28
2.11
1.1
1.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
187
1687
1.66
2.09
25.2
14.9
ml/min/173m2
75.5
76.2
0.16
167
1378
(3024263) Appearance of Synovial fluid
5
10
5.09
2.08
1.2
1.3
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
7
20
3.58
2.07
1.1
1.1
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
36
228
1.69
2.04
7.9
5.8
mmol/l
2.2
1.5
0.52
28
180
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
8
26
3.15
2.03
1.1
1.5
pg
29.6
31.8
—
8
26
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
18
92
2.04
1.96
11.9
7.1
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
17
85
2.08
1.96
3.3
3.5
mmol/l
24.7
24.6
0.08
17
78
(3044290) Cell count panel - Cerebral spinal fluid
8
27
3.03
1.95
1.0
1.2
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
5
11
4.62
1.95
1.0
1.0
—
—
—
0
0
(44790047)
6
16
3.82
1.95
1.7
1.4
—
—
—
0
0
(44806118)
6
16
3.82
1.95
1.7
1.4
—
—
—
0
0
(44790048)
6
16
3.82
1.95
1.7
1.4
—
—
—
0
0
(44790049)
6
16
3.82
1.95
1.7
1.4
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
16
79
2.10
1.90
1.9
2.0
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
41
274
1.61
1.89
25.0
24.5
inr
1.8
1.3
—
5
29
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
7
22
3.25
1.89
1.0
1.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
6
17
3.60
1.85
1.0
1.1
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
5
12
4.23
1.83
1.6
1.3
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
7
23
3.11
1.81
1.1
1.0
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
15
74
2.10
1.79
2.1
2.7
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
5
13
3.91
1.72
1.2
1.3
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
56
411
1.48
1.71
4.4
4.1
kg/l
1.0
1.0
—
8
59
(3048689) Calprotectin [Mass/mass] in Stool
32
207
1.64
1.68
2.7
2.1
ug/g
208.2
151.4
0.30
27
162
(3020564) Creatinine [Moles/volume] in Serum or Plasma
203
1896
1.75
1.67
30.9
18.0
umol/l
82.4
77.7
1.05
203
1896
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
7
26
2.75
1.59
1.1
1.1
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
6
20
3.05
1.59
1.0
1.1
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
70
545
1.41
1.56
4.0
3.0
mmol/l
6.7
7.0
0.28
59
455
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
10
44
2.33
1.55
1.2
1.4
—
—
—
0
0
(1002224) Polysomnography panel
11
51
2.22
1.53
1.0
1.1
—
—
—
0
0
(4268621)
5
15
3.38
1.53
1.4
1.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
72
565
1.40
1.53
4.8
3.9
mg/mmol
7.3
8.5
0.19
47
351
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
7
27
2.64
1.52
1.3
1.2
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
7
27
2.64
1.52
1.4
2.1
%
61.9
58.6
—
7
27
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
9
37
2.49
1.49
1.3
1.7
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
7
28
2.55
1.46
1.3
1.4
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
18
103
1.81
1.46
1.5
1.2
—
32.9
—
0
8
(40761511) CBC panel - Blood by Automated count
199
1864
1.61
1.43
21.8
14.6
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
14
74
1.95
1.42
1.8
1.9
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
10
46
2.23
1.42
2.1
6.2
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
202
1903
1.63
1.36
19.5
10.3
u/l
25.9
23.6
0.95
194
1825
(3045142) Bone marrow Pathology biopsy report
5
18
2.82
1.29
1.0
1.2
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
18
108
1.72
1.26
1.1
1.2
iu/ml
28.5
120.8
—
6
43
(3007461) Platelets [#/volume] in Blood
207
1968
1.68
1.25
40.4
22.4
e9/l
260.1
247.2
1.73
201
1912
(3048929) Epstein Barr virus Ab [Presence] in Serum
9
45
2.04
1.25
1.4
1.3
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
96
812
1.32
1.22
5.6
4.2
ng/l
25.5
42.6
1.75
71
586
(3047007) Chlamydophila sp Ab [Presence] in Serum
5
19
2.67
1.22
1.4
1.1
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
5
19
2.67
1.22
1.0
1.1
—
—
—
0
0
(3035941) MCH [Entitic mass]
207
1970
1.67
1.22
40.1
22.3
pg
30.2
30.3
0.44
202
1930
(3024731) MCV [Entitic volume]
207
1970
1.67
1.22
40.3
22.3
fl
91.7
91.4
0.44
202
1930
(3026361) Erythrocytes [#/volume] in Blood
207
1970
1.67
1.22
40.3
22.4
e12/l
4.4
4.4
0.57
200
1909
(3010813) Leukocytes [#/volume] in Blood
207
1970
1.67
1.22
40.4
22.4
e9/l
7.4
6.6
5.51
200
1910
(3000963) Hemoglobin [Mass/volume] in Blood
207
1971
1.66
1.20
40.8
22.5
g/l
130.1
132.4
1.62
202
1930
(3016650) Hepatitis A virus Ab [Presence] in Serum
6
26
2.34
1.19
1.2
1.0
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
182
1691
1.41
1.18
7.6
6.1
mmol/mol
41.7
40.6
0.85
166
1553
(3022145) Colonoscopy Study observation
31
218
1.49
1.17
1.4
1.3
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
5
20
2.53
1.15
4.8
3.2
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
7
30
2.38
1.13
1.3
1.4
—
—
—
0
0
(3044889) 12 lead EKG panel
143
1287
1.31
1.12
4.8
4.1
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
66
536
1.33
1.10
4.1
3.1
mg/l
44.0
281.6
0.81
45
346
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
187
1752
1.41
1.10
5.8
4.8
mmol/l
5.8
6.0
1.26
171
1571
(3037121) Protein [Mass/volume] in Urine
12
68
1.81
1.02
3.8
3.3
g/l
0.2
0.3
—
5
24
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
9
49
1.87
1.00
1.1
1.5
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
7
37
1.92
0.95
2.3
2.8
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
10
55
1.86
0.93
2.1
1.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
9
52
1.76
0.93
1.0
1.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
28
2.17
0.92
1.8
1.6
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
179
1680
1.33
0.91
4.6
4.1
mmol/l
1.3
1.2
0.91
162
1500
(3023323) Follitropin [Units/volume] in Serum or Plasma
8
42
1.94
0.89
1.4
1.4
iu/l
27.6
22.4
—
8
35
(3009214) Lutropin [Units/volume] in Serum or Plasma
6
30
2.03
0.87
1.2
1.2
u/l
12.9
9.0
—
6
23
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
113
0.52
0.85
1.5
1.8
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
8
45
1.81
0.85
4.3
2.3
mg/l
2.2
1.6
—
8
40
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
16
107
1.53
0.78
3.0
4.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
23
167
1.42
0.77
3.4
3.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
21
150
1.44
0.76
11.7
7.1
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
11
67
1.67
0.76
2.2
2.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
167
1568
1.26
0.75
28.5
16.2
%
38.6
39.0
0.25
122
1056
(3024522) Salmonella sp identified in Specimen by Organism specific culture
5
24
2.11
0.75
1.2
1.7
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
5
24
2.11
0.75
1.2
1.7
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
24
2.11
0.75
1.2
1.7
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
17
117
1.49
0.74
1.6
1.4
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
5
25
2.02
0.73
2.0
1.6
—
—
—
0
0
(3019060) Gas panel - Arterial blood
19
135
1.45
0.72
3.7
3.5
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
22
161
1.41
0.71
1.5
1.7
%
1.6
1.4
1.15
22
135
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
184
1751
1.28
0.71
5.1
4.6
mmol/l
4.6
4.6
0.08
172
1588
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
183
1741
1.28
0.70
5.1
4.6
mmol/l
1.5
1.5
1.15
170
1567
(3012544) pH of Venous blood
25
188
1.37
0.70
3.4
3.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
23
171
1.38
0.69
5.6
4.0
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
44
1.61
0.65
1.7
1.5
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
16
112
1.46
0.65
4.8
2.5
e9/l
3.9
3.8
0.06
11
81
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
33
264
1.29
0.63
1.4
1.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
49
574
0.81
0.60
3.2
3.3
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
7
111
0.62
0.60
1.4
1.3
—
—
—
0
0
(4281824)
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
12
81
1.51
0.58
2.5
1.9
ug/l
1.1
4.8
0.50
12
69
(3021901) Oxygen saturation in Capillary blood
6
36
1.68
0.57
3.7
2.6
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
55
474
1.21
0.56
1.5
1.6
mmol/l
1.5
1.3
0.70
48
391
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
9
60
1.52
0.55
1.3
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
61
1.50
0.54
1.3
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
61
1.50
0.54
1.3
1.2
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
50
429
1.21
0.54
1.7
1.8
pmol/l
448.8
471.4
0.17
42
358
(3003694) ABO and Rh group [Type] in Blood
52
448
1.21
0.53
1.5
1.4
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
47
1.50
0.48
1.7
1.5
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
51
444
1.19
0.47
4.9
5.5
ug/l
2.3
2.9
0.29
45
385
(3028626) Oxygen [Partial pressure] in Capillary blood
7
48
1.47
0.47
3.3
2.4
kpa
7.7
7.9
—
7
41
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
19
148
1.31
0.45
4.0
3.0
ml/min/173m2
57.4
63.1
—
7
60
(1616796) Gas panel - Central venous blood
7
51
1.38
0.44
1.9
2.6
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
186
1798
1.20
0.44
5.7
5.2
mmol/l
2.7
2.7
0.20
174
1618
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
20
158
1.29
0.43
1.6
1.7
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
12
87
1.40
0.43
1.1
1.0
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
26
218
1.22
0.36
1.9
4.1
ug/l
3.8
38.8
0.60
18
185
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
6
42
1.44
0.36
3.0
2.5
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
14
109
1.30
0.34
1.1
1.3
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
7
56
1.26
0.29
1.1
1.5
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
26
224
1.18
0.28
3.1
3.7
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
117
0.76
0.28
1.6
1.4
—
—
—
0
0
(3020891) Body temperature
6
82
0.72
0.24
3.0
4.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
11
88
1.26
0.23
2.3
1.3
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
5
42
1.19
0.21
1.2
1.8
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
10.4
—
0.7
—
0
10
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3035880) pH of Pleural fluid
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
6
49
1.23
0.20
1.5
1.3
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
6
50
1.21
0.20
1.5
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
11
90
1.23
0.19
1.7
1.6
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
12
100
1.21
0.18
1.8
1.2
—
—
—
0
0
(4034850)
5
67
0.74
0.17
27.8
10.6
—
—
—
0
0
(3000492) Spirometry study
17
149
1.15
0.16
1.7
1.5
—
—
—
0
0
(40768443) Skin Pathology biopsy report
9
80
1.13
0.15
1.2
1.2
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
37
349
1.07
0.10
3.3
4.9
%
17.2
21.5
1.54
18
181
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
22
238
0.92
0.10
10.0
7.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
114
0.87
0.09
2.7
2.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
25
268
0.92
0.09
1.6
1.4
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
27
253
1.08
0.09
3.1
3.1
ug/l
0.9
0.8
0.23
18
168
(40768793) Breast Pathology biopsy report
5
60
0.83
0.08
1.2
1.3
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
6
70
0.85
0.08
3.0
5.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
11
103
1.07
0.02
2.5
2.0
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
10
107
0.93
0.02
1.8
2.5
%
1.2
1.1
—
10
107
(4035726)
18
175
1.03
0.00
1.2
1.3
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
6
69
0.87
0.00
2.8
3.6
mmol/l
3.9
4.0
—
6
61
(3017704) Immunofixation for Urine
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761539) Cells [Type] in Urine sediment by Light microscopy
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood
0
5
0.00
0.00
0.0
1.0
—
1.2
—
0
5
(3035933) Granulocytes/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
15.0
—
2346.0
—
0
8
(3008536) Aspergillus sp Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
60
1.00
0.00
2.0
1.4
—
—
—
0
0
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40757373) Influenza virus identified in Isolate
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3033799) Differential panel - Peritoneal fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
6
65
0.92
0.00
1.2
1.9
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
12.5
—
1168.1
—
0
8
(3011544) Albumin [Mass/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.0
—
19.2
—
0
6
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022907) Direct antiglobulin test.polyspecific reagent [Presence] on Red Blood Cells
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
9
0.00
0.00
0.0
2.1
—
13.7
—
0
9
(40758292) HTLV I+II Ab panel - Serum
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_MULTIFIBRO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MULTIFIBRO | 1.619 [1.38, 1.9] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.019 |
During the follow-up period (1.1.1998 — 31.12.2019), 528 out of 1187 females with M13_MULTIFIBRO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MULTIFIBRO | 1.371 [1.09, 1.72] | 0.006 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 229 out of 481 males with M13_MULTIFIBRO died.
Mortality risk
Mortality risk for people of age
years, who have M13_MULTIFIBRO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.105% | 0.27% |
| 5 | 0.745% | 1.63% |
| 10 | 1.866% | 3.975% |
| 15 | 3.45% | 7.504% |
| 20 | 6.278% | 13.11% |
Relationships between endpoints
↥Index endpoint: M13_MULTIFIBRO – Multifocal fibrosclerosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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