Chronic myeloid leukaemia, excluding all cancers (controls excluding all cancers)

C3_CML_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C92.1
  • Hospital discharge: ICD-9 2051A
  • Hospital discharge: ICD-8 20515
  • Cause of death: ICD-10 C92.1
  • Cause of death: ICD-9 2051A
  • Cause of death: ICD-8 20515
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9863|9875
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

319

4. Check minimum number of events

None

319

5. Include endpoints

None

319

6. Filter based on genotype QC (FinnGen only)

319

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 319 145 174
Unadjusted period prevalence (%) 0.06 0.05 0.08
Median age at first event (years) 58.32 57.50 59.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
142
Matched controls
1419
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
202.0
141
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3516.3
175.5
135
7
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
+∞
164.2
124
*
189
Kela drug reimbursment
Imatinib
+∞
131.5
105
*
L01XE01
ATC
[U] imatinib; oral
+∞
105.9
88
*
XW000
NOMESCO Finland
Bone marrow biopsy
88.6
70.6
76
18
M04AA01
ATC
allopurinol; systemic
26.6
61.2
98
109
L01XX05
ATC
hydroxycarbamide; oral
156.4
56.9
57
6
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
+∞
51.2
46
*
316
Kela drug reimbursment
Imatinib
+∞
46.4
42
*
152
Kela drug reimbursment
Nilotinib
+∞
39.4
36
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
119.2
34.6
36
*
L01XX28
ATC
[D] imatinib; oral
+∞
33.7
31
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
33.7
31
*
L01XE08
ATC
[U] nilotinib; oral
+∞
28.0
26
*
150
Kela drug reimbursment
Dasatinib
+∞
28.0
26
*
L03AA02
ATC
filgrastim; parenteral
+∞
25.8
24
*
212
Kela drug reimbursment
Gout
51.4
24.7
29
7
L01XE06
ATC
[U] dasatinib; systemic
+∞
24.7
23
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
22.5
21
*
328
Kela drug reimbursment
Nilotinib
+∞
20.3
19
*
L01EA03
ATC
nilotinib; oral
+∞
20.3
19
*
127
Kela drug reimbursment
Transplant complication
42.9
18.2
22
6
324
Kela drug reimbursment
Dasatinib
+∞
18.1
17
*
L01EA02
ATC
dasatinib; oral
+∞
18.1
17
*
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
18.1
17
*
A05AA02
ATC
ursodeoxycholic acid; oral
51.3
12.1
14
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
38.5
11.5
14
*
L04AA01
ATC
[U] ciclosporin; systemic
27.7
11.4
15
6
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
118.3
10.6
11
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
+∞
10.5
10
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
43.4
10.1
12
*
WW500
NOMESCO Finland
Blood transfusion
14.8
9.9
16
12
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
59.1
9.8
11
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
9.5
9
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
9.5
9
*
L03AA04
ATC
NA
+∞
9.5
9
*
R50.9
ICD-10 Finland
Fever, unspecified
4.2
9.4
38
113
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
39.4
9.2
11
*
WW200
NOMESCO Finland
Immunization
11.8
9.0
16
15
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
95.4
8.5
9
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
8.4
74
388
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
8.4
8
*
170
Kela drug reimbursment
Bosutinib
+∞
8.4
8
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
8.4
8
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
+∞
8.4
8
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.7
7.8
22
44
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
7.7
31
91
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
84.2
7.5
8
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
7.3
7
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.8
7.3
20
39
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.3
6.9
38
143
C03CA01
ATC
furosemide; systemic
2.8
6.8
55
265
A03FA01
ATC
metoclopramide; systemic, rectal
3.9
6.5
27
81
A01AB04
ATC
amphotericin B; local oral
6.3
6.4
16
28
B73
ICPC
Leukaemia
+∞
6.3
6
*
2051A
ICD-9 Finland
Myeloid leukaemia, Chronic
+∞
6.3
6
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
6.3
6
*
J05AB11
ATC
valaciclovir; oral
3.7
6.2
27
85
B99
ICD-10 Finland
Other and unspecified infectious diseases
13.3
6.2
10
8
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.7
6.1
20
48
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
6.0
49
233

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
92
22
58.36
158.35
1.5
1.1
—
—
—
0
0
97
33
41.80
152.03
2.5
2.0
—
—
—
0
0
146
219
11.45
102.79
4.5
2.3
68.2
67.3
e9/l
0.09
111
173
163
302
9.99
95.57
5.4
2.1
1.8
1.7
%
0.37
157
274
117
175
9.98
80.80
9.0
4.2
2.7
0.7
%
4.91
61
41
102
159
8.96
67.12
8.7
4.4
1.6
0.3
%
4.00
39
32
217
748
6.95
63.61
20.5
5.4
—
—
—
0
0
41
18
25.99
57.22
1.3
1.1
—
—
—
0
0
93
168
7.40
52.73
10.4
4.3
0.4
0.1
%
2.70
58
37
261
1202
7.44
51.35
20.3
5.0
0.6
0.6
e9/l
0.63
252
1048
89
159
7.38
50.87
9.7
4.4
1.3
2.5
%
0.18
44
35
261
1208
7.38
50.87
20.4
5.0
0.0
0.0
e9/l
0.22
251
1055
262
1232
7.31
49.65
20.5
5.0
2.0
1.9
e9/l
0.36
253
1087
91
171
7.05
49.46
2.3
2.1
8.8
11.1
g/l
5.98
85
157
263
1249
7.30
49.02
22.2
5.2
0.2
0.2
e9/l
0.64
255
1106
185
679
5.11
46.55
6.7
2.3
341.0
8643.8
umol/l
3.57
177
599
267
1347
7.03
44.49
29.3
6.2
3.6
4.3
e9/l
4.18
257
1187
60
100
7.16
35.98
1.8
2.0
1.3
1.4
g/l
0.68
53
87
70
139
6.17
35.29
1.3
1.4
1.1
1.1
g/l
0.02
65
129
38
37
11.52
34.90
1.2
1.1
—
—
—
0
0
232
1180
4.54
34.31
14.9
5.4
1.2
1.2
mmol/l
0.43
204
1017
144
531
4.12
33.70
15.1
4.1
—
—
—
0
0
66
132
6.04
32.91
1.3
1.4
—
—
—
0
0
35
33
11.79
32.78
1.1
1.2
138.3
110.4
u/ml
—
9
5
163
687
3.81
30.80
11.3
3.1
7.4
7.4
ph
0.72
31
106
210
1071
3.81
29.12
13.4
4.7
1.2
1.2
mmol/l
0.18
202
956
28
25
12.18
27.04
2.3
1.9
33.6
34.1
pg
0.19
28
25
96
306
4.06
26.79
3.2
2.4
22.8
23.2
%
0.12
83
265
24
17
15.18
26.49
1.6
1.4
—
—
—
0
0
24
17
15.18
26.49
1.6
1.4
—
—
—
0
0
24
17
15.18
26.49
1.6
1.4
—
—
—
0
0
24
17
15.18
26.49
1.6
1.4
—
—
—
0
0
31
36
9.43
24.94
6.6
3.8
53.2
58.1
%
0.94
31
36
38
58
7.30
24.41
1.5
1.2
—
—
—
0
0
20
12
17.71
23.92
4.1
2.0
726.7
835.4
e6/l
—
7
5
24
22
11.72
22.70
10.9
3.0
—
—
—
0
0
137
606
3.21
22.43
6.9
3.6
—
—
—
0
0
28
35
8.67
21.22
6.5
3.3
3.0
4.5
e9/l
2.32
28
35
21
18
12.42
20.66
8.3
2.7
46.8
50.3
%
0.15
13
12
20
16
13.27
20.50
2.2
2.3
—
—
—
0
0
20
16
13.27
20.50
1.1
1.1
—
—
—
0
0
123
542
3.07
19.84
21.7
4.6
—
—
—
0
0
123
552
3.00
19.08
7.4
3.2
90.7
89.9
%
0.12
117
544
187
1054
2.87
18.84
26.8
7.8
0.0
0.0
e9/l
0.72
172
864
76
276
3.30
16.73
1.6
1.5
—
—
—
0
0
134
669
2.73
16.56
5.7
2.0
—
—
—
0
0
16
13
12.90
16.14
4.4
2.4
0.9
0.8
e9/l
—
10
7
124
603
2.73
16.05
2.8
2.1
2.8
3.0
mg/l
0.36
114
510
149
797
2.63
15.88
3.3
2.3
58.0
57.6
u/l
0.05
144
734
225
1475
2.78
15.69
8.4
4.0
6.8
6.7
mmol/l
0.04
219
1371
25
39
6.87
15.61
1.1
1.2
352.1
232.6
u/ml
0.95
19
22
66
237
3.25
14.68
1.6
1.5
—
—
—
0
0
174
1034
2.50
14.45
8.5
3.5
—
—
—
0
0
31
65
5.17
14.34
1.1
1.2
—
—
—
0
0
172
1024
2.47
14.13
4.3
2.6
264.0
131.5
ug/l
3.30
166
945
18
6
31.65
14.03
2.9
1.7
—
—
—
0
0
166
978
2.45
13.88
6.9
8.6
1.2
1.3
inr
0.81
45
260
22
36
6.49
13.11
1.0
1.0
—
—
—
0
0
32
83
4.17
11.41
2.6
1.7
1.9
2.1
ug/l
0.06
32
76
48
165
3.25
11.34
1.3
1.3
—
—
—
0
0
22
43
5.42
10.95
1.1
1.0
—
—
—
0
0
131
760
2.23
10.62
6.7
2.0
2.3
2.4
mmol/l
2.41
125
634
45
166
2.99
9.40
3.0
2.6
7.4
3.9
e9/l
0.61
38
122
19
38
5.25
9.21
1.4
1.2
—
—
—
0
0
10
10
10.29
8.68
1.7
1.9
—
—
—
0
0
12
16
7.75
8.47
1.8
1.1
20620.5
20495.3
e6/l
—
6
10
88
470
2.20
8.45
1.5
1.3
2.1
2.7
g/l
3.68
69
276
14
23
6.32
8.25
1.1
1.2
—
—
—
0
0
11
5
22.70
8.07
3.5
1.0
—
—
—
0
0
119
728
2.01
7.91
2.4
1.6
—
—
—
0
0
70
351
2.27
7.78
1.7
1.7
—
—
—
0
0
69
344
2.28
7.77
2.0
1.8
—
—
—
0
0
17
37
4.80
7.49
1.0
1.3
—
—
—
0
0
93
536
2.04
7.19
1.9
1.7
1.6
1.0
mg/l
1.06
76
406
17
40
4.43
6.84
2.2
2.5
—
—
—
0
0
57
277
2.29
6.77
9.5
5.7
12.2
11.6
kpa
0.48
52
267
11
18
6.29
6.47
1.5
1.1
—
—
—
0
0
56
277
2.24
6.37
9.6
5.7
1.1
1.6
mmol/l
0.31
39
218
6
0
+∞
6.27
1.0
0.0
—
—
—
0
0
87
514
1.95
6.17
1.8
1.8
1253.1
1159.2
nmol/l
0.41
81
391
102
636
1.89
6.15
1.9
1.5
20.2
21.3
nmol/l
0.30
93
543
112
722
1.85
6.07
4.8
2.9
28.7
154.5
e6/l
0.76
97
546
58
299
2.15
5.94
2.1
1.6
—
—
—
0
0
8
5
16.35
5.43
1.4
1.0
—
—
—
0
0
38
170
2.40
5.42
1.3
1.1
—
—
—
0
0
9
8
11.53
5.32
6.6
1.4
0.2
0.2
e9/l
—
9
8
9
8
11.53
5.32
1.4
1.0
—
—
—
0
0
82
509
1.82
4.88
3.2
2.2
5.0
4.6
e6/l
0.10
77
434
97
639
1.74
4.71
4.5
2.7
—
—
—
0
0
89
572
1.77
4.70
1.6
1.3
—
—
—
0
0
30
129
2.46
4.67
1.6
1.2
—
—
—
0
0
7
5
14.27
4.59
1.0
1.0
—
—
—
0
0
148
1107
1.63
4.37
2.3
2.0
92.1
95.2
pmol/l
0.32
103
555
229
1914
1.70
4.30
6.1
4.0
14.1
11.4
mm/h
1.95
222
1756
137
1009
1.63
4.28
3.7
3.6
24.6
75.9
ng/l
0.86
111
712
16
51
3.25
4.27
1.8
2.1
129.4
132.5
g/l
—
10
36
51
287
1.92
4.08
2.0
1.4
—
—
—
0
0
98
672
1.66
4.02
4.6
2.8
0.6
0.4
e6/l
0.22
86
488
53
304
1.89
4.01
13.8
5.0
104.0
104.2
mmol/l
0.05
53
297
71
447
1.76
3.97
4.2
2.0
2.4
2.4
mmol/l
0.11
71
382
117
843
1.61
3.93
5.5
3.4
87.0
91.8
e6/l
0.04
103
592
13
39
3.43
3.80
1.2
1.2
—
—
—
0
0
6
5
12.19
3.77
1.5
1.2
—
—
—
0
0
9
16
5.75
3.68
1.3
1.2
—
—
—
0
0
43
238
1.93
3.61
5.5
3.2
2.5
2.3
mmol/l
0.10
35
194
44
250
1.88
3.42
5.5
3.3
—
—
—
0
0
34
177
2.03
3.39
4.0
4.2
—
—
—
0
0
7
10
7.13
3.38
1.0
1.1
—
—
—
0
0
17
65
2.71
3.36
4.7
2.9
—
—
—
0
0
16
60
2.75
3.28
1.6
1.3
237.1
323.9
ug/g
—
9
36
39
216
1.92
3.28
2.8
3.2
—
—
—
0
0
6
8
7.62
3.06
1.0
1.0
—
—
—
0
0
54
338
1.72
3.06
1.3
1.4
349.1
491.6
titre
0.40
11
79
7
12
5.94
3.03
1.9
1.1
—
—
—
0
0
12
40
3.08
3.00
3.0
3.1
3.0
2.7
mmol/l
—
6
20
11
35
3.22
2.96
2.5
2.2
—
—
—
0
0
201
1705
1.48
2.88
5.2
4.0
—
—
—
0
0
23
110
2.18
2.86
4.4
4.1
24.3
25.0
mmol/l
0.39
23
104
39
229
1.80
2.75
7.9
3.6
—
—
—
0
0
11
37
3.04
2.72
1.4
2.4
59331.6
6730.4
u/l
—
5
14
6
10
6.09
2.71
1.0
1.1
—
—
—
0
0
6
10
6.09
2.71
6.8
1.7
—
—
—
0
0
209
1802
1.46
2.64
5.4
3.8
—
—
—
0
0
25
130
2.00
2.53
4.5
3.5
—
—
—
0
0
150
1223
1.43
2.53
3.8
3.6
0.0
0.0
estimate
0.00
25
196
12
45
2.73
2.48
2.3
2.1
—
—
—
0
0
33
195
1.77
2.30
16.2
6.3
—
—
—
0
0
147
1209
1.40
2.29
5.0
4.9
0.0
0.0
estimate
0.00
30
200
31
183
1.77
2.17
4.0
3.2
—
—
—
0
0
7
19
3.74
2.16
1.4
1.1
—
—
—
0
0
12
49
2.51
2.13
3.0
3.4
7.4
7.4
ph
0.06
12
39
274
2539
1.56
2.05
36.9
12.0
19.7
23.0
mg/l
0.90
250
1936
6
15
4.06
2.05
1.5
1.3
—
—
—
0
0
6
15
4.06
2.05
1.0
1.3
—
—
—
0
0
39
250
1.64
2.05
1.3
1.3
—
—
—
0
0
22
119
1.91
2.03
19.6
7.5
—
—
—
0
0
91
703
1.41
1.99
3.5
3.1
—
—
—
0
0
7
21
3.38
1.97
1.0
1.0
—
—
—
0
0
144
1203
1.36
1.96
3.7
3.5
0.0
0.0
estimate
0.00
28
203
231
2081
1.40
1.93
47.8
14.3
14.7
13.6
%
20.57
231
2038
117
955
1.36
1.82
3.0
3.4
—
—
—
0
0
70
524
1.43
1.82
6.0
3.8
131.0
319.3
ng/l
0.90
60
414
6
18
3.38
1.75
2.0
1.4
—
—
—
0
0
7
24
2.96
1.73
1.7
1.5
90.6
90.5
%
—
7
24
6
19
3.20
1.67
1.3
1.2
—
—
—
0
0
6
19
3.20
1.67
6.8
1.8
—
—
—
0
0
213
1916
1.34
1.64
4.1
3.7
15.1
14.8
pmol/l
0.66
205
1724
24
146
1.70
1.56
2.6
2.3
—
—
—
0
0
12
228
0.51
1.52
1.3
1.4
—
—
—
0
0
5
16
3.16
1.44
1.0
1.4
15.2
16.7
ug/l
—
5
16
72
567
1.35
1.38
3.3
3.6
—
—
—
0
0
17
97
1.79
1.38
1.3
1.2
—
—
—
0
0
81
657
1.31
1.27
4.1
3.7
0.0
0.0
estimate
0.50
25
199
6
25
2.43
1.25
5.2
1.1
—
—
—
0
0
41
300
1.42
1.22
2.1
2.3
235.4
114.3
ug/g
0.75
31
232
17
101
1.72
1.22
1.9
1.7
—
—
—
0
0
8
37
2.19
1.22
2.4
2.3
106.0
105.0
mmol/l
—
8
37
8
37
2.19
1.22
2.4
2.3
4.0
4.1
mmol/l
—
8
37
8
37
2.19
1.22
2.4
2.3
—
—
—
0
0
6
26
2.33
1.19
2.0
2.3
—
—
—
0
0
10
50
2.03
1.17
1.2
1.2
—
—
—
0
0
91
763
1.27
1.11
3.8
3.8
—
—
—
0
0
14
81
1.76
1.11
2.5
3.4
4.0
3.9
mmol/l
0.11
14
75
5
21
2.40
1.09
4.6
1.1
—
—
—
0
0
13
74
1.79
1.08
1.1
1.1
—
111.4
—
0
7
71
584
1.28
1.01
4.1
3.7
1.0
1.0
kg/l
2.44
14
88
65
529
1.29
1.00
1.5
1.7
508.0
13380717.6
pmol/l
0.50
52
426
5
23
2.19
0.98
2.0
2.8
—
—
—
0
0
20
133
1.54
0.97
2.6
2.2
0.6
0.7
%
0.21
20
133
9
51
1.79
0.95
3.0
1.1
—
—
—
0
0
6
27
2.24
0.94
1.3
1.3
—
—
—
0
0
20
135
1.51
0.91
2.6
3.5
—
—
—
0
0
10
56
1.81
0.89
2.2
2.1
—
—
—
0
0
11
64
1.74
0.87
2.8
1.7
174.9
259.1
pmol/l
1.99
11
59
78
662
1.24
0.85
3.7
3.2
—
—
—
0
0
24
172
1.43
0.83
2.5
2.6
—
—
—
0
0
8
48
1.68
0.79
1.0
1.9
—
—
—
0
0
5
100
0.49
0.78
1.0
1.1
—
—
—
0
0
6
34
1.78
0.76
1.3
1.4
68.5
65.3
pmol/l
—
6
34
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
7
38
1.86
0.74
1.0
1.1
—
—
—
0
0
92
808
1.19
0.71
3.6
3.3
3232.2
144.2
mg/l
1.56
67
518
21
152
1.41
0.71
1.4
1.7
—
—
—
0
0
13
85
1.55
0.70
1.2
1.2
—
—
—
0
0
5
28
1.80
0.66
14.4
3.4
6.2
7.4
mmol/l
—
5
21
5
28
1.80
0.66
3.2
1.1
—
—
—
0
0
5
28
1.80
0.66
3.2
1.1
—
—
—
0
0
5
30
1.68
0.61
2.0
1.1
—
—
—
0
0
5
30
1.68
0.61
1.4
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
4807.5
—
0
15
7
111
0.62
0.59
1.1
1.1
—
—
—
0
0
41
343
1.22
0.53
1.2
1.2
—
—
—
0
0
11
155
0.70
0.49
1.0
1.4
—
—
—
0
0
42
356
1.21
0.49
23.1
24.6
1.2
1.3
inr
—
6
55
241
2324
1.15
0.48
5.1
4.5
1.9
2.4
mu/l
0.53
232
2110
255
2473
1.16
0.45
5.0
4.1
1.6
1.3
mmol/l
1.51
246
2263
11
78
1.42
0.43
3.6
1.8
—
—
—
0
0
6
93
0.64
0.43
8.2
7.1
—
—
—
0
0
279
2847
0.84
0.42
55.2
17.8
8.1
6.7
e9/l
0.79
274
2762
84
920
0.88
0.42
3.3
3.0
—
—
—
0
0
5
33
1.52
0.41
1.0
1.7
—
—
—
0
0
279
2846
0.84
0.41
55.1
17.8
4.0
4.5
e12/l
28.68
274
2760
0
18
0.00
0.40
0.0
1.8
—
7.7
—
0
13
14
106
1.34
0.40
4.5
4.0
—
—
—
0
0
15
192
0.77
0.39
1.7
1.4
—
—
—
0
0
93
858
1.12
0.37
4.3
4.0
19.7
8.7
mg/mmol
0.80
61
549
261
2668
0.88
0.35
28.6
11.6
—
—
—
0
0
73
669
1.12
0.33
1.7
1.7
2.1
1.4
mmol/l
1.06
65
555
14
176
0.79
0.33
1.2
1.2
—
—
—
0
0
21
174
1.22
0.32
1.6
1.3
—
36.2
—
0
10
11
84
1.32
0.30
1.0
1.1
—
—
—
0
0
7
55
1.28
0.30
2.4
2.7
—
—
—
0
0
16
195
0.81
0.29
1.0
1.2
—
—
—
0
0
9
74
1.22
0.25
3.8
4.4
—
—
—
0
0
50
546
0.90
0.25
2.4
2.5
0.7
0.7
ug/l
0.01
31
352
6
82
0.73
0.24
1.3
1.6
—
—
—
0
0
90
851
1.08
0.22
3.5
3.2
8.2
7.8
mmol/l
0.38
77
713
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
3.0
—
—
—
0
0
0
12
0.00
0.21
0.0
11.8
—
0.6
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
4.0
—
32.0
—
0
8
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
49
453
1.10
0.20
1.2
1.3
1.3
12.7
u/ml
3.13
17
170
50
464
1.09
0.19
1.2
1.3
17.1
33.3
iu/ml
1.65
16
146
17
195
0.86
0.18
1.5
1.4
—
—
—
0
0
259
2625
0.93
0.17
5.7
5.1
2.5
2.7
mmol/l
4.81
251
2420
8
71
1.13
0.16
2.0
1.6
—
—
—
0
0
26
284
0.91
0.14
1.7
1.6
—
—
—
0
0
250
2526
0.95
0.10
5.4
4.6
6.1
6.0
mmol/l
0.83
236
2294
5
44
1.14
0.10
1.0
2.6
—
—
—
0
0
8
76
1.05
0.07
1.0
2.1
—
—
—
0
0
8
77
1.04
0.07
1.0
2.1
—
—
—
0
0
8
78
1.03
0.07
1.0
1.6
—
—
—
0
0
21
197
1.07
0.06
3.0
2.5
—
8.0
—
0
7
100
984
1.02
0.04
4.2
3.7
7.4
1.9
ug/l
0.48
92
879
243
2419
1.02
0.02
6.3
6.1
39.1
40.3
mmol/mol
1.67
231
2256
231
2319
0.99
0.01
38.8
13.0
36.9
40.4
%
5.77
153
1629
23
223
1.03
0.01
2.1
1.4
—
—
—
0
0
257
2571
1.00
0.00
5.4
4.6
4.3
4.6
mmol/l
4.64
252
2377
255
2553
0.99
0.00
5.2
4.5
1.3
1.5
mmol/l
6.73
247
2351
53
533
0.99
0.00
1.2
1.2
1.0
1.8
u/ml
—
9
142
16
156
1.03
0.00
1.2
1.3
30.7
118.3
iu/ml
—
6
63
5
55
0.91
0.00
1.2
3.5
—
—
—
0
0
0
9
0.00
0.00
0.0
4.6
—
5.8
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
1.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
0.00
1.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
367.8
—
0
6
8
79
1.01
0.00
1.0
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
21.9
—
0
5
0
5
0.00
0.00
0.0
6.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
7.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_CML_EXALLC – Chronic myeloid leukaemia, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).