info icon

Exposure to excessive heat of man-made origin

VWXY20_ALTIS_IHMIS_AIKAANSAAMAL_VOIMA_KUUMU

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 W92
  • Cause of death: ICD-10 W92

2 out of 7 registries used, show all original rules.

268

4. Check minimum number of events

None

268

5. Include endpoints

None

268

6. Filter based on genotype QC (FinnGen only)

268

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
W8[5-9]|W9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 268 91 177
Unadjusted period prevalence (%) 0.06 0.03 0.08
Median age at first event (years) 66.78 58.69 70.94

-FinnGen-

Age distribution of first events

020304050607080010203040506070AgeIndividuals

-FinnGen-

Year distribution of first events

1970197519801985199019952000200520102015202020230102030405060708090YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
223
Matched controls
2229
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
W92
ICD-10 Finland
Exposure to excessive heat of man-made origin
+∞
313.6
220
*
S14
ICPC
Burn/scald
19.4
28.1
43
27
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
44.6
25.6
31
8
T23.2
ICD-10 Finland
Burn of second degree of wrist and hand
54.5
17.3
20
*
T21.2
ICD-10 Finland
Burn of second degree of trunk
51.6
16.3
19
*
X12
ICD-10 Finland
Contact with other hot fluids
42.1
10.1
12
*
QBD20
NOMESCO Finland
Excision of burn of trunk and coverage
104.2
9.5
10
*
QCD20
NOMESCO Finland
Excision of burn of upper limb and coverage
+∞
9.4
9
*
T24.2
ICD-10 Finland
Burn of second degree of hip and lower limb, except ankle and foot
52.0
8.7
10
*
T31.0
ICD-10 Finland
Burns involving less than 10% of body surface
52.0
8.7
10
*
T22.2
ICD-10 Finland
Burn of second degree of shoulder and upper limb, except wrist and hand
21.0
8.6
12
6
QDD00
NOMESCO Finland
Dressing of major burn of lower limb
93.4
8.5
9
*
QCD00
NOMESCO Finland
Dressing of major burn of upper limb
93.4
8.5
9
*
T23.0
ICD-10 Finland
Burn of unspecified degree of wrist and hand
+∞
8.4
8
*
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
12.3
8.2
14
12
X14
ICD-10 Finland
Contact with hot air and gases
46.6
7.8
9
*
QBD00
NOMESCO Finland
Dressing of major burn of trunk
41.3
6.8
8
*
T20.2
ICD-10 Finland
Burn of second degree of head and neck
41.3
6.8
8
*
X18
ICD-10 Finland
Contact with other hot metals
23.3
6.7
9
*
T25.3
ICD-10 Finland
Burn of third degree of ankle and foot
71.8
6.5
7
*
T23.1
ICD-10 Finland
Burn of first degree of wrist and hand
71.8
6.5
7
*
T30.0
ICD-10 Finland
Burn of unspecified body region, unspecified degree
71.8
6.5
7
*
T29.3
ICD-10 Finland
Burns of multiple regions, at least one burn of third degree mentioned
+∞
6.3
6
*
T22.1
ICD-10 Finland
Burn of first degree of shoulder and upper limb, except wrist and hand
+∞
6.3
6
*
T21.0
ICD-10 Finland
Burn of unspecified degree of trunk
+∞
6.3
6
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.9
6.1
16
29
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.0
6.1
23
62

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
14
27
5.42
7.05
1.9
1.4
—
—
—
0
0
51
239
2.40
6.68
2.1
1.8
—
—
—
0
0
172
2062
0.54
5.32
17.7
14.4
—
—
—
0
0
190
2191
0.54
4.61
27.9
22.3
4.46
4.49
e12/l
0.41
180
2123
190
2191
0.54
4.61
27.9
22.4
6.97
6.90
e9/l
0.17
181
2120
190
2190
0.55
4.58
27.8
22.3
251.25
242.09
e9/l
1.03
181
2128
16
49
3.41
4.54
2.1
1.3
—
—
—
0
0
155
1870
0.59
4.11
4.1
4.5
1.42
1.40
mmol/l
0.26
147
1685
162
1929
0.59
4.00
4.5
5.0
2.63
2.65
mmol/l
0.06
153
1739
37
659
0.49
4.00
2.3
3.1
—
—
—
0
0
6
5
12.23
3.78
2.5
1.2
—
—
—
0
0
16
56
2.98
3.69
2.1
1.3
—
—
—
0
0
182
2091
0.60
3.63
11.9
10.2
25.95
26.29
u/l
0.11
175
2009
152
1822
0.62
3.62
3.8
4.0
1.30
1.28
mmol/l
0.09
143
1630
19
75
2.65
3.55
3.5
2.3
947.33
339.20
ug/l
1.05
19
70
159
1882
0.62
3.52
4.1
4.5
4.46
4.49
mmol/l
0.09
151
1714
16
58
2.87
3.49
2.1
1.3
—
—
—
0
0
16
58
2.87
3.49
2.1
1.3
—
—
—
0
0
62
911
0.58
3.39
3.9
4.9
1.89
2.65
ug/l
0.77
52
792
16
59
2.82
3.39
2.1
1.3
—
—
—
0
0
28
517
0.49
3.29
2.8
2.9
0.68
0.77
ug/l
0.39
19
332
33
177
1.99
3.08
8.5
7.1
11.63
9.87
mmol/l
0.61
33
165
152
1793
0.65
3.00
21.9
16.3
39.98
39.65
%
0.21
103
1271
152
1792
0.65
2.98
5.5
6.1
42.71
40.79
mmol/mol
1.07
141
1657
12
41
3.02
2.89
2.8
1.4
—
—
—
0
0
15
59
2.63
2.84
2.1
1.3
—
—
—
0
0
7
14
5.10
2.74
1.4
1.2
—
—
—
0
0
0
69
0.00
2.64
0.0
4.8
—
—
—
0
0
163
1876
0.67
2.62
3.9
4.6
6.41
6.03
mmol/l
0.60
154
1681
15
62
2.50
2.59
1.1
1.5
—
—
—
0
0
7
16
4.46
2.49
1.0
1.1
—
—
—
0
0
112
1372
0.68
2.39
3.8
4.0
—
—
—
0
0
10
35
2.93
2.33
1.1
1.2
—
—
—
0
0
152
1749
0.70
2.19
4.6
4.3
1.92
1.98
mu/l
0.19
143
1554
11
44
2.56
2.04
2.5
4.6
—
—
—
0
0
7
173
0.39
1.99
1.4
1.4
—
—
—
0
0
179
1987
0.70
1.94
20.5
15.6
28.57
25.36
mg/l
0.55
152
1600
12
52
2.37
1.90
2.8
3.2
33.25
34.39
umol/l
0.09
12
44
11
46
2.45
1.87
1.9
2.3
—
—
—
0
0
80
624
1.40
1.70
4.7
4.4
—
—
—
0
0
10
43
2.38
1.62
1.1
1.2
—
—
—
0
0
8
32
2.54
1.61
1.6
1.1
—
—
—
0
0
6
21
2.90
1.51
1.0
1.2
—
—
—
0
0
11
53
2.12
1.40
1.4
1.2
—
—
—
0
0
0
37
0.00
1.35
0.0
2.7
—
—
—
0
0
9
42
2.18
1.35
2.4
2.8
—
—
—
0
0
26
169
1.60
1.35
1.5
1.5
—
—
—
0
0
14
77
1.86
1.28
2.0
4.2
0.10
0.23
g/l
—
7
31
32
222
1.50
1.26
1.3
1.4
240.00
401.51
titre
—
5
53
46
602
0.72
1.26
4.7
4.1
—
—
—
0
0
5
19
2.66
1.22
1.4
1.3
—
—
—
0
0
42
554
0.71
1.20
3.7
3.4
—
—
—
0
0
74
895
0.76
1.20
9.6
9.8
0.00
0.00
e9/l
0.40
57
722
14
233
0.58
1.18
1.4
1.3
—
—
—
0
0
27
186
1.50
1.11
5.6
6.5
7.42
7.41
ph
—
5
17
5
21
2.41
1.09
1.0
1.3
14258.40
55056.67
e6/l
—
5
12
5
21
2.41
1.09
4.8
2.9
—
—
—
0
0
37
488
0.72
1.06
1.6
1.7
1.44
1.35
mmol/l
0.27
31
404
5
22
2.30
1.04
1.0
1.3
695.40
2765.60
e6/l
—
5
15
29
208
1.44
0.99
1.8
1.6
—
—
—
0
0
5
23
2.20
0.98
1.2
1.1
—
—
—
0
0
0
30
0.00
0.98
0.0
5.2
—
11.40
—
0
25
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
6
27
2.25
0.94
8.8
4.3
408.17
339.64
umol/l
—
6
22
76
639
1.26
0.93
2.9
2.4
—
—
—
0
0
32
237
1.40
0.93
2.9
3.1
12.19
7.78
umol/l
0.40
26
204
84
970
0.80
0.89
4.2
3.7
0.00
0.00
estimate
0.00
13
192
25
181
1.42
0.83
8.4
4.4
—
—
—
0
0
34
260
1.35
0.83
1.8
1.6
—
—
—
0
0
6
32
1.89
0.82
1.3
1.1
—
—
—
0
0
128
1408
0.83
0.81
3.8
3.6
14.96
14.84
pmol/l
0.23
120
1249
62
732
0.80
0.79
1.9
2.1
—
—
—
0
0
133
1454
0.83
0.78
4.4
4.0
14.79
12.74
mm/h
0.56
122
1333
40
317
1.31
0.78
2.4
1.8
—
—
—
0
0
5
24
2.10
0.75
5.0
3.0
—
—
—
0
0
5
24
2.10
0.75
1.0
1.0
—
—
—
0
0
143
1547
0.84
0.72
8.4
7.3
85.78
81.20
u/l
0.38
135
1447
11
69
1.62
0.69
10.7
11.9
—
—
—
0
0
52
617
0.80
0.69
5.1
3.9
23.08
11.38
mg/mmol
0.46
33
404
26
197
1.35
0.69
16.2
9.2
—
—
—
0
0
119
1303
0.84
0.68
4.7
3.1
54.12
49.54
u/l
0.32
113
1213
86
968
0.84
0.67
5.2
5.0
0.00
0.00
estimate
0.00
12
193
15
105
1.45
0.61
1.8
2.8
4.39
4.60
pmol/l
0.33
15
90
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
88
980
0.85
0.60
4.1
3.8
0.00
0.00
estimate
0.00
13
182
8
53
1.52
0.59
1.3
1.4
—
—
—
0
0
8
53
1.52
0.59
1.3
1.4
—
58.00
—
0
5
16
115
1.42
0.58
12.6
9.2
—
—
—
0
0
6
36
1.68
0.57
3.0
4.5
58.00
64.00
%
—
6
36
12
171
0.69
0.57
1.2
1.4
—
—
—
0
0
9
62
1.47
0.53
3.6
3.1
—
—
—
0
0
38
318
1.23
0.51
3.1
2.3
2.25
2.33
g/l
0.36
33
287
18
136
1.35
0.50
1.6
1.4
—
—
—
0
0
50
576
0.84
0.50
4.8
3.1
101.34
306.61
mg/l
0.68
32
378
7
108
0.64
0.49
1.6
1.4
—
—
—
0
0
62
546
1.18
0.49
2.3
2.0
2.64
3.09
mg/l
0.93
53
467
7
46
1.54
0.48
2.7
1.2
—
—
—
0
0
44
377
1.20
0.47
4.0
3.5
83.48
409.93
ng/l
0.77
33
297
57
501
1.17
0.46
6.0
4.1
85.14
86.74
%
0.20
57
487
36
424
0.83
0.46
3.2
4.7
—
—
—
0
0
71
636
1.16
0.46
3.8
3.4
28.66
156.32
e6/l
0.69
53
498
17
219
0.76
0.46
1.2
1.3
—
—
—
0
0
44
507
0.84
0.45
6.6
6.4
—
—
—
0
0
32
267
1.23
0.44
9.2
6.9
0.97
1.27
mmol/l
0.20
23
209
41
352
1.19
0.43
3.1
2.2
14.59
12.75
umol/l
0.32
36
318
28
231
1.24
0.43
12.1
4.8
—
—
—
0
0
78
707
1.15
0.43
4.6
5.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
0.98
—
0
15
0
15
0.00
0.41
0.0
1.7
—
400.80
—
0
5
0
15
0.00
0.41
0.0
1.3
—
2.30
—
0
9
35
299
1.20
0.39
3.0
2.3
25.16
20.82
%
0.75
30
256
34
290
1.20
0.39
25.4
27.4
0.96
1.22
inr
—
5
31
49
432
1.16
0.39
3.5
2.7
5.20
4.28
e6/l
0.36
43
384
21
170
1.26
0.38
2.8
3.0
65.48
66.35
g/l
0.18
21
152
61
548
1.15
0.38
3.3
3.1
—
—
—
0
0
49
433
1.16
0.38
1.9
1.9
1.20
1.29
mg/l
0.12
36
337
19
152
1.27
0.38
1.3
1.1
—
—
—
0
0
12
157
0.75
0.37
5.7
4.1
1.23
1.22
mmol/l
0.18
12
139
19
153
1.26
0.36
2.4
1.6
—
—
—
0
0
49
549
0.87
0.36
5.0
3.9
0.00
0.00
estimate
0.00
13
187
73
794
0.89
0.34
1.8
2.0
92.59
91.66
pmol/l
0.06
46
399
13
100
1.32
0.34
3.3
2.5
—
—
—
0
0
7
53
1.33
0.31
1.9
1.3
12.77
22.99
iu/l
—
7
44
14
174
0.79
0.30
1.4
1.4
—
—
—
0
0
14
174
0.79
0.30
4.3
3.7
—
—
—
0
0
62
676
0.89
0.30
3.0
3.0
2.33
2.34
mmol/l
0.46
54
584
10
75
1.35
0.30
1.2
1.2
—
—
—
0
0
79
849
0.90
0.30
5.0
4.1
27.25
49.51
ng/l
2.13
60
625
8
106
0.75
0.29
1.1
1.2
—
38.61
—
0
9
29
253
1.16
0.27
1.2
1.2
—
—
—
0
0
48
435
1.13
0.27
4.0
3.7
—
—
—
0
0
62
571
1.11
0.27
3.7
3.2
0.91
0.38
e6/l
0.37
44
436
5
74
0.67
0.26
1.2
1.5
—
—
—
0
0
37
412
0.88
0.26
1.9
1.8
1537.10
1184.72
nmol/l
0.70
29
309
105
996
1.09
0.25
5.0
5.3
0.64
0.61
e9/l
0.53
86
855
35
313
1.14
0.24
2.8
1.9
—
—
—
0
0
41
451
0.89
0.24
4.9
3.9
1.02
1.02
kg/l
—
8
58
5
38
1.32
0.23
2.8
1.5
—
—
—
0
0
105
1000
1.08
0.23
5.0
5.4
0.04
0.04
e9/l
1.02
86
863
34
377
0.89
0.22
2.6
3.2
2.47
2.45
mmol/l
0.46
27
333
5
42
1.19
0.21
1.2
5.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
69.00
—
0
6
0
12
0.00
0.21
0.0
1.1
—
30.00
—
0
7
131
1358
0.93
0.21
4.8
4.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
1.53
—
0
7
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
76
718
1.08
0.20
4.5
3.9
77.23
69.61
e6/l
0.05
51
527
6
49
1.23
0.20
1.5
1.1
—
—
—
0
0
7
59
1.19
0.18
3.6
2.5
7.44
7.42
ph
—
7
48
62
585
1.08
0.17
2.7
3.2
—
—
—
0
0
8
69
1.16
0.16
1.3
1.1
—
—
—
0
0
18
159
1.14
0.15
3.2
3.7
—
—
—
0
0
12
103
1.17
0.14
1.4
1.3
106.21
346.08
u/ml
0.50
12
92
104
1006
1.06
0.14
11.4
7.1
1.21
1.21
mmol/l
0.01
96
846
9
108
0.83
0.13
1.1
1.3
—
—
—
0
0
114
1173
0.95
0.13
7.7
9.0
4.59
4.30
e9/l
0.53
90
1014
17
189
0.89
0.12
2.0
1.6
—
—
—
0
0
87
841
1.05
0.11
9.0
9.8
1.27
1.30
inr
0.09
21
238
14
124
1.14
0.11
4.9
2.4
—
—
—
0
0
97
941
1.05
0.11
5.2
5.4
2.98
2.81
%
0.34
92
877
28
300
0.93
0.10
1.3
1.3
22.08
38.64
iu/ml
—
6
92
60
624
0.95
0.10
4.3
3.0
6.43
7.84
mmol/l
2.15
55
510
5
45
1.11
0.10
1.6
1.4
—
—
—
0
0
25
233
1.08
0.09
1.4
1.3
—
—
—
0
0
41
430
0.95
0.09
1.4
1.2
0.63
1.82
u/ml
—
7
120
105
1026
1.04
0.08
5.0
5.5
1.93
1.91
e9/l
0.05
91
900
7
64
1.10
0.08
1.3
1.6
—
—
—
0
0
122
1243
0.97
0.08
9.6
5.0
7.47
6.76
mmol/l
1.88
115
1167
13
143
0.90
0.07
1.8
1.4
—
—
—
0
0
9
103
0.87
0.06
1.3
1.2
—
—
—
0
0
26
273
0.95
0.05
1.3
1.3
0.99
12.30
u/ml
—
8
96
16
149
1.08
0.05
7.4
7.0
—
—
—
0
0
85
834
1.03
0.05
3.3
2.6
192.38
143.40
ug/l
0.32
80
757
105
1034
1.03
0.05
5.7
5.6
0.22
0.19
e9/l
1.01
90
900
39
403
0.96
0.04
1.7
1.4
2.87
2.67
g/l
0.22
28
239
27
279
0.96
0.02
13.3
6.6
103.22
104.46
mmol/l
0.58
27
270
15
142
1.06
0.02
3.1
2.9
—
—
—
0
0
21
218
0.96
0.02
1.9
2.2
44.21
161.49
ug/g
3.66
16
170
10
93
1.08
0.02
17.7
4.2
—
—
—
0
0
52
527
0.98
0.01
1.6
1.4
—
—
—
0
0
16
162
0.99
0.00
8.6
3.6
—
—
—
0
0
43
428
1.01
0.00
2.7
2.9
477.66
566.75
mosm/kgh2o
1.96
35
371
59
593
0.99
0.00
4.9
4.1
7.39
7.40
ph
0.40
12
109
107
1067
1.00
0.00
7.6
6.2
14.42
13.65
umol/l
0.12
101
1010
33
334
0.99
0.00
3.0
3.1
0.71
1.88
e6/l
1.84
17
199
5
59
0.84
0.00
1.0
1.4
—
4.48
—
0
6
0
9
0.00
0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
0.00
0.0
4.8
—
53.00
—
0
9
5
59
0.84
0.00
1.8
5.1
73.30
31.07
mg/l
—
5
48
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
4.9
—
—
—
0
0
7
73
0.96
0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.4
—
1.28
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
5.7
3.6
36.85
37.38
g/l
—
6
54
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
40.00
—
0
6
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
8.19
—
0
5
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
40.6
—
137.80
—
0
5
0
7
0.00
0.00
0.0
1.0
—
18.47
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
5.4
—
—
—
0
0
8
83
0.96
0.00
1.8
1.7
0.35
4.61
ug/l
—
8
70
0
8
0.00
0.00
0.0
1.0
—
1707.75
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
8
81
0.99
0.00
4.3
3.1
3.81
4.03
mmol/l
—
8
73
0
6
0.00
0.00
0.0
1.0
—
178.50
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_ALTIS_IHMIS_AIKAANSAAMAL_VOIMA_KUUMU – Exposure to excessive heat of man-made origin

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).