obsolete_meningioma: ['A tumor of meningothelial cells that are manifested in the central nervous system and arise from the arachnoid "cap" cells of the arachnoid villi in the meninges.']
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
579 |
4. Check minimum number of eventsNone |
579 |
5. Include endpointsNone |
579 |
6. Filter based on genotype QC (FinnGen only) |
562 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D32
- Name in latin
- Neoplasma benignum meningum non specificatarum
Similar endpoints
↥List of similar endpoints to
Beningn neoplasm: Meninges, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of meninges
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4723 | 3470 | 1207 |
| Only index persons | 3764 | 2825 | 939 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.03 |
| Only index persons | 0.09 | 0.10 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 67.64 | 68.49 | 64.97 |
| Only index persons | 65.31 | 65.95 | 63.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 562 | 406 | 156 |
| Unadjusted period prevalence (%) | 0.12 | 0.14 | 0.07 |
| Median age at first event (years) | 63.37 | 61.82 | 67.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 579
- Matched controls
- 5790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
122.1
307.7
166
19
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
111.0
307.7
183
24
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
153.6
307.7
237
26
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
212.3
307.7
294
28
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
+∞
307.7
576
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
13.6
196.4
230
267
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
71.0
155.2
85
14
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
37.8
106.6
67
20
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
10.0
90.5
114
138
N03AX14
ATC
levetiracetam; systemic
14.5
86.3
82
65
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
131.1
84.6
89
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.5
77.0
76
64
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
15.1
71.9
66
49
H02AB02
ATC
dexamethasone; systemic
5.2
62.4
160
398
G40.9
ICD-10 Finland
Epilepsy, unspecified
10.2
61.2
73
81
AA1AD
NOMESCO Finland
CT of head and brain
3.7
52.0
275
1141
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
12.9
51.2
51
43
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
14.1
49.9
47
36
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
49.2
116
265
N03AB02
ATC
phenytoin; systemic
14.2
49.1
46
35
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
14.2
49.1
46
35
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
11.8
48.4
51
47
XCK00
NOMESCO Finland
Perimetry
5.7
48.1
100
204
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.7
40.7
161
540
ZXC95
NOMESCO Finland
Use of surgical navigator
11.9
36.6
38
34
D32.03
ICD-10 Finland
Benign meningioma in ventricles
191.5
35.2
36
*
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
345.8
33.2
33
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
180.2
33.1
34
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
180.2
33.1
34
*
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
120.2
32.0
34
*
N03AF02
ATC
oxcarbazepine; oral
6.7
31.4
52
84
N03AF01
ATC
carbamazepine; oral, rectal
4.9
31.1
75
172
AA1BD
NOMESCO Finland
Extensive CT of head and brain
7.8
30.1
43
59
XA800
NOMESCO Finland
Neuropsychological investigation
6.4
30.0
52
88
N03AG01
ATC
valproic acid; systemic, rectal
4.7
27.8
70
166
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
101.6
26.9
29
*
R51.80
ICD-10 Finland
Headache
3.0
24.5
134
533
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.0
23.2
32
42
D32.05
ICD-10 Finland
Cerebral meninges
47.0
22.5
27
6
H53.4
ICD-10 Finland
Visual field defects
7.4
22.3
33
47
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.6
21.5
53
123
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
20.2
154
720
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.6
19.8
49
114
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
19.4
81
273
D32
ICD-10 Finland
Benign neoplasm of meninges
196.1
18.6
19
*
WX882
NOMESCO Finland
High dependency care
5.9
18.4
34
61
9531/0-C70.0
ICD-O-3
Meningothelial meningioma of cerebral meninges
185.4
17.6
18
*
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
26.5
17.0
23
9
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
20.0
17.0
25
13
N75
ICPC
Benign neoplasm nervous system
+∞
16.7
16
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
16.7
16
*
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
92.8
16.6
18
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
28.5
16.6
22
8
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
16.5
181
981
9539/1-C70.0
ICD-O-3
Atypical meningioma of cerebral meninges
+∞
15.7
15
*
ZXC40
NOMESCO Finland
Use of ultrasound
20.7
13.9
20
10
9532/0-C70.0
ICD-O-3
Fibrous meningioma of cerebral meninges
143.2
13.5
14
*
H53.2
ICD-10 Finland
Diplopia
4.3
13.2
35
86
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
10.4
13.1
25
25
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
14.5
12.8
21
15
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
12.6
88
389
AAK00
NOMESCO Finland
Cranioplasty
132.8
12.5
13
*
N03AX18
ATC
lacosamide; systemic
15.1
11.9
19
13
H47.2
ICD-10 Finland
Optic atrophy
30.7
11.7
15
5
Z2445
NOMESCO Finland
Psychologist
4.3
11.7
30
72
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
+∞
11.5
11
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
11.4
53
189
ZX050
NOMESCO Finland
Stereotactic radiotherapy
17.5
11.2
17
10
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
13.1
11.2
19
15
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
11.2
130
709
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
28.6
10.8
14
5
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
28.6
10.8
14
5
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
21.9
10.7
15
7
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
61.2
10.7
12
*
N18
ICPC
Paralysis/weakness
4.9
10.6
23
48
Z3231
NOMESCO Finland
Registered nurse
1.9
10.5
177
1095
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
10.4
38
117
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
10.4
97
484
G40.10
ICD-10 Finland
Simple partial seizures
11.6
10.1
18
16
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.2
9.8
39
127
22520
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
56.0
9.7
11
*
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
101.6
9.4
10
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
101.6
9.4
10
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
11.7
9.1
16
14
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
9.1
238
1665
N76
ICPC
Neoplasm nervous system unspecified
37.3
9.0
11
*
WF002
NOMESCO Finland
Radical radiotherapy
3.1
9.0
37
123
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
10.9
8.8
16
15
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
8.7
77
375
WF099
NOMESCO Finland
Other radiotherapy
16.6
8.6
13
8
183
Kela drug reimbursment
Lamotrigin and topiramate
10.2
8.6
16
16
H02AB09
ATC
hydrocortisone; systemic
4.3
8.5
22
53
9537/0-C70.0
ICD-O-3
Transitional meningioma of cerebral meninges
28.0
8.5
11
*
2152
FHL
Extraction, big brain
28.0
8.5
11
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.6
8.4
49
198
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.9
8.3
24
63
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
8.0
163
1057
N03AX09
ATC
lamotrigine; oral
3.2
7.8
31
101
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
9.6
7.8
15
16
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.4
7.8
28
86
G91.1
ICD-10 Finland
Obstructive hydrocephalus
18.6
7.6
11
6
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
12.1
7.6
13
11
C70.0
ICD-10 Finland
Malignant neoplasm: Cerebral meninges
81.1
7.4
8
*
8000/0-C70.0
ICD-O-3
Neoplasm, benign of cerebral meninges
81.1
7.4
8
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
7.4
100
570
8000/0-C70.9
ICD-O-3
Neoplasm, benign of meninges, NOS
+∞
7.3
7
*
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
7.3
7
*
D33.0
ICD-10 Finland
Benign neoplasm: Brain, supratentorial
+∞
7.3
7
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
7.2
51
226
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
6.7
7.2
17
26
G93.0
ICD-10 Finland
Cerebral cysts
20.3
7.2
10
5
G91.0
ICD-10 Finland
Communicating hydrocephalus
12.2
7.1
12
10
F05.9
ICD-10 Finland
Delirium, unspecified
4.1
6.9
19
48
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
6.9
217
1565
R4130
NOMESCO Finland
Speech therapy
3.7
6.8
21
58
WX872
NOMESCO Finland
Intensive care
2.8
6.8
34
127
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.7
69
357
R51
ICD-10 Finland
Headache
2.7
6.7
35
134
N80
ICPC
Head injury other
4.1
6.7
18
45
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
6.6
69
359
ZXD05
NOMESCO Finland
Urgent procedure
1.7
6.6
169
1157
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
70.6
6.4
7
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
70.6
6.4
7
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
14.5
6.4
10
7
G50.1
ICD-10 Finland
Atypical facial pain
3.8
6.4
19
51
TAB00
NOMESCO Finland
Lumbar puncture
2.7
6.3
34
132
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
6.3
123
781
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
18.2
6.3
9
5
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
6.3
6
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.1
6.2
14
20
R4110
NOMESCO Finland
Physiotherapy
1.6
6.2
164
1128
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
6.2
48
222
XKD00
NOMESCO Finland
Uroflowmetry
1.9
6.2
76
419
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.8
6.1
18
48
G50.0
ICD-10 Finland
Trigeminal neuralgia
3.5
6.1
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
46
36
13.79
48.25
1.5
2.1
—
—
—
0
0
144
713
2.36
16.27
2.2
1.8
28.79
29.41
s
0.79
139
687
27
48
5.85
14.74
2.3
1.2
—
—
—
0
0
240
1505
2.02
14.56
2.7
2.1
264.74
229.73
u/l
0.12
232
1417
349
2515
1.98
13.94
6.9
6.1
1.21
1.22
mmol/l
1.01
311
2141
39
104
3.95
13.20
1.9
1.3
1052.88
197.43
e6/l
0.77
34
82
39
104
3.95
13.20
1.8
1.2
10.32
13.85
e6/l
0.17
31
79
371
2793
1.91
12.30
5.7
4.4
6.72
6.72
mmol/l
0.01
357
2608
40
117
3.60
11.88
1.6
1.2
985.10
475.37
mg/l
1.60
40
110
109
546
2.23
11.67
5.8
6.5
1.16
1.41
mmol/l
0.36
81
446
91
425
2.35
11.48
2.4
1.9
371.89
376.64
nmol/l
0.07
84
390
178
1127
1.84
9.69
2.3
2.3
—
—
—
0
0
178
1147
1.80
9.04
4.0
3.6
91.93
90.98
%
0.19
173
1113
18
24
7.70
8.21
2.4
1.3
—
—
—
0
0
306
2335
1.66
8.14
13.5
15.2
1.22
1.26
inr
0.33
98
662
287
2170
1.64
7.80
2.8
2.5
—
—
—
0
0
43
174
2.59
7.35
1.6
1.7
—
—
—
0
0
299
2306
1.61
7.34
6.4
5.3
1.20
1.22
mmol/l
2.90
280
2077
258
1935
1.60
7.02
4.7
3.9
46.77
54.71
ng/l
0.12
199
1399
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
36
137
2.74
6.94
2.2
2.3
0.39
0.34
u/ml
0.30
19
77
44
189
2.44
6.66
1.6
1.9
—
—
—
0
0
121
779
1.70
5.89
1.9
1.9
—
—
—
0
0
330
2697
1.52
5.67
9.6
8.5
4.03
4.09
e9/l
0.21
297
2356
116
752
1.68
5.48
2.7
3.0
0.82
0.81
mmol/l
0.53
105
693
312
2541
1.49
5.31
6.1
5.7
12.30
10.96
umol/l
0.35
296
2394
200
1492
1.52
5.18
2.6
2.4
77.47
62.05
u/l
0.28
184
1363
53
274
2.03
5.16
4.0
2.9
4.04
4.50
pmol/l
3.20
48
231
276
2220
1.46
4.84
7.4
5.7
26.82
27.44
%
0.37
253
2065
52
274
1.99
4.82
1.6
1.7
—
—
—
0
0
270
2192
1.43
4.36
7.1
5.4
58.30
57.60
%
0.38
248
2040
71
431
1.74
4.24
2.4
2.6
4.47
6.14
ug/l
0.67
57
374
28
127
2.27
3.83
1.9
1.5
—
—
—
0
0
71
450
1.66
3.63
7.7
6.9
122.28
120.55
g/l
0.32
71
442
51
300
1.77
3.42
7.8
7.2
0.65
0.69
%
0.35
51
295
171
1326
1.41
3.39
3.3
3.0
0.40
0.47
e6/l
0.16
139
1005
51
301
1.76
3.38
7.8
7.0
1.33
1.32
%
0.04
51
296
49
289
1.76
3.26
1.2
1.4
—
—
—
0
0
62
393
1.65
3.18
2.5
3.2
167.99
217.71
ng/l
0.41
54
362
14
50
2.84
3.10
1.1
1.1
—
—
—
0
0
126
940
1.44
3.07
4.7
3.8
302.60
274.47
ng/l
0.04
96
749
62
397
1.63
3.07
5.2
5.7
7.53
9.70
mmol/l
2.58
56
373
414
3745
1.37
2.93
8.5
7.1
77.23
78.26
u/l
0.20
391
3471
397
3578
1.35
2.80
5.2
4.3
12.83
13.29
mm/h
0.24
373
3274
181
1459
1.35
2.76
3.4
3.2
42.55
114.59
e6/l
0.87
147
1122
12
40
3.04
2.71
1.2
1.1
—
—
—
0
0
293
2537
1.31
2.70
2.9
2.7
—
—
—
0
0
211
1747
1.33
2.67
3.3
3.2
—
—
—
0
0
243
2053
1.32
2.66
2.1
2.0
97.14
97.22
pmol/l
0.01
112
1014
86
616
1.47
2.59
4.5
4.5
0.98
1.03
mmol/l
1.09
76
554
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
25
3.64
2.58
1.1
1.2
—
—
—
0
0
9
26
3.50
2.49
1.2
1.1
—
—
—
0
0
13
51
2.58
2.46
2.0
2.3
—
—
—
0
0
248
2137
1.28
2.24
4.6
4.2
34.76
35.30
g/l
0.82
228
1976
12
48
2.53
2.20
1.2
1.1
—
—
—
0
0
35
212
1.69
2.18
2.1
1.8
1.64
2.51
ug/l
0.22
29
189
28
159
1.80
2.17
2.7
2.0
—
—
—
0
0
22
116
1.93
2.13
4.0
2.2
3.32
3.84
g/l
1.16
22
111
405
3723
1.29
2.12
5.2
4.1
14.77
14.90
pmol/l
0.43
381
3338
5
10
5.03
2.07
1.0
1.1
—
—
—
0
0
53
368
1.48
1.90
1.3
1.6
—
—
—
0
0
74
549
1.40
1.87
1.8
1.8
—
—
—
0
0
184
1558
1.27
1.85
3.4
3.0
1988.59
1385.03
ng/l
0.65
157
1323
26
153
1.73
1.83
1.2
1.2
—
—
—
0
0
97
756
1.34
1.82
2.9
2.8
2.27
2.91
e6/l
0.47
55
408
125
1011
1.30
1.81
1.7
1.7
949.31
1193.01
nmol/l
2.62
92
740
74
553
1.39
1.80
1.9
1.8
—
—
—
0
0
126
1022
1.30
1.78
2.8
2.5
5.10
6.54
e6/l
0.65
118
927
46
316
1.50
1.75
7.5
6.9
24.92
24.73
mmol/l
0.19
46
302
8
30
2.69
1.73
1.3
1.3
—
—
—
0
0
8
30
2.69
1.73
1.3
1.3
—
—
—
0
0
5
13
3.87
1.72
1.0
1.3
—
—
—
0
0
7
25
2.82
1.65
1.1
1.3
—
—
—
0
0
102
813
1.31
1.64
2.9
2.6
1.34
1.23
e6/l
0.13
59
461
61
451
1.39
1.60
5.2
3.1
2.41
2.21
mmol/l
0.21
49
359
6
20
3.02
1.58
1.0
1.4
—
—
—
0
0
236
2087
1.22
1.56
2.5
2.3
76.91
79.63
nmol/l
0.78
210
1829
66
497
1.37
1.55
3.4
3.4
—
—
—
0
0
486
4643
1.29
1.46
21.1
14.7
22.73
22.71
mg/l
0.01
425
3696
29
188
1.57
1.46
3.9
3.8
1.02
1.34
mmol/l
2.51
29
182
12
59
2.06
1.44
1.3
1.5
—
—
—
0
0
39
271
1.47
1.44
1.3
1.4
—
35.42
—
0
18
9
39
2.33
1.43
1.3
1.3
—
—
—
0
0
20
118
1.72
1.43
2.1
1.6
3.09
5.49
iu/l
—
9
32
67
516
1.34
1.38
2.7
2.5
5.17
7.41
umol/l
1.48
55
445
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
140
1191
1.23
1.32
2.4
2.1
2.87
3.23
mg/l
1.11
121
1009
131
1107
1.24
1.32
1.7
1.7
457.21
13728128.46
pmol/l
0.78
114
896
8
34
2.37
1.29
1.3
1.2
—
—
—
0
0
23
146
1.60
1.28
1.6
1.6
0.18
0.48
iu/ml
—
8
28
315
2903
1.19
1.25
3.3
3.1
48.83
48.30
u/l
0.04
287
2679
194
1718
1.19
1.21
3.2
3.2
2.35
2.36
mmol/l
0.58
172
1491
6
26
2.32
1.19
2.0
2.2
—
—
—
0
0
77
622
1.27
1.15
5.1
4.6
33.30
33.11
%
0.06
56
405
11
58
1.91
1.12
1.7
1.4
—
—
—
0
0
16
96
1.69
1.11
1.1
2.3
117.50
129.49
g/l
—
8
67
458
4385
1.21
1.10
18.6
13.7
77.39
76.66
ml/min/173m2
0.30
411
3579
37
270
1.40
1.09
3.7
2.8
0.12
0.18
e6/l
0.46
37
263
8
41
1.96
1.09
1.1
1.2
—
81.83
—
0
6
458
4387
1.21
1.09
6.4
5.0
1.84
2.23
mu/l
0.76
428
3966
5
22
2.28
1.03
1.4
2.1
—
—
—
0
0
217
1964
1.17
1.03
3.1
2.6
109.53
117.01
ug/l
0.26
195
1792
10
53
1.90
1.02
1.3
1.7
—
—
—
0
0
5
23
2.18
0.98
2.6
2.8
425.80
754.30
u/ml
—
5
23
37
277
1.36
0.96
2.0
3.9
2.55
2.05
mmol/l
0.31
27
220
6
27
2.23
0.93
1.2
1.0
—
—
—
0
0
76
634
1.23
0.89
8.0
7.6
—
—
—
0
0
20
136
1.49
0.87
1.1
1.2
—
—
—
0
0
10
57
1.77
0.84
1.3
1.6
—
—
—
0
0
500
4861
1.21
0.83
24.5
17.2
3.96
3.97
mmol/l
0.58
493
4716
120
1055
1.17
0.81
2.1
1.6
1.17
1.17
mg/l
0.01
92
822
6
34
1.77
0.76
1.2
1.2
—
—
—
0
0
51
415
1.25
0.76
3.1
3.5
1.24
1.23
mmol/l
0.42
51
355
161
1456
1.15
0.75
3.4
3.0
26.84
30.66
u/l
2.12
153
1379
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
498
4853
1.19
0.72
24.6
17.1
139.56
139.69
mmol/l
0.43
491
4719
91
791
1.18
0.71
1.4
1.3
4.38
14.36
u/ml
1.62
31
303
51
420
1.23
0.70
2.5
2.9
65.40
66.51
g/l
0.56
46
379
5
27
1.86
0.68
1.0
1.0
—
—
—
0
0
17
119
1.44
0.67
2.4
3.2
0.89
0.81
nmol/l
—
10
94
10
62
1.62
0.65
2.3
1.5
—
—
—
0
0
10
62
1.62
0.65
2.3
1.5
—
—
—
0
0
7
44
1.60
0.65
1.9
1.4
—
—
—
0
0
16
112
1.44
0.64
1.2
1.4
—
—
—
0
0
12
79
1.53
0.63
1.2
1.3
—
—
—
0
0
65
754
0.84
0.61
1.4
1.4
—
—
—
0
0
5
30
1.67
0.61
3.8
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
10
64
1.57
0.59
1.1
1.1
—
—
—
0
0
8
54
1.49
0.57
1.4
1.1
—
—
—
0
0
6
36
1.67
0.57
1.2
2.7
—
—
—
0
0
10
65
1.55
0.56
1.2
1.4
—
—
—
0
0
10
65
1.55
0.56
1.2
1.4
—
—
—
0
0
10
65
1.55
0.56
1.2
1.4
—
—
—
0
0
10
66
1.52
0.53
1.2
1.4
—
—
—
0
0
6
40
1.51
0.51
1.3
1.7
—
—
—
0
0
500
4903
1.14
0.51
24.2
17.4
76.41
76.14
umol/l
0.06
500
4903
16
118
1.37
0.50
1.9
1.7
—
—
—
0
0
105
950
1.13
0.50
5.8
4.9
3.10
2.82
ug/l
0.20
85
839
10
67
1.50
0.50
1.2
1.4
—
—
—
0
0
10
67
1.50
0.50
1.2
1.4
—
—
—
0
0
10
144
0.69
0.49
1.3
1.6
—
—
—
0
0
108
982
1.12
0.48
2.9
2.8
2.45
2.46
mmol/l
0.61
87
854
131
1206
1.11
0.47
1.5
1.5
20.10
21.49
nmol/l
0.54
116
1009
20
155
1.30
0.47
1.4
1.2
—
—
—
0
0
12
163
0.73
0.44
1.5
1.3
373.43
295.42
ug/g
—
7
97
250
2385
1.08
0.42
5.3
4.0
0.02
0.01
estimate
0.26
60
473
5
33
1.52
0.41
1.2
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
71
637
1.13
0.40
2.7
2.2
20.22
21.60
%
0.41
58
542
5
34
1.47
0.40
9.0
3.3
—
—
—
0
0
5
34
1.47
0.40
1.2
1.3
87.20
76.47
umol/l
—
5
34
250
2391
1.08
0.39
7.7
5.5
0.00
0.00
estimate
-0.00
51
432
75
677
1.12
0.39
2.5
2.2
2.35
2.36
g/l
0.09
66
625
12
158
0.75
0.37
1.2
1.4
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
10
72
1.40
0.37
1.2
1.1
—
—
—
0
0
10
72
1.40
0.37
2.3
1.6
—
—
—
0
0
252
2418
1.07
0.36
5.3
4.1
0.00
0.01
estimate
0.80
49
422
24
199
1.21
0.35
1.6
2.1
—
—
—
0
0
81
740
1.11
0.35
2.6
2.2
12.34
12.67
umol/l
0.16
71
680
19
154
1.24
0.34
1.4
1.2
—
—
—
0
0
14
109
1.29
0.33
8.6
6.6
107.50
105.13
mmol/l
1.06
14
101
14
109
1.29
0.33
1.4
1.3
—
—
—
0
0
195
1860
1.07
0.32
5.8
4.3
—
—
—
0
0
139
1309
1.08
0.32
5.1
4.4
0.00
0.00
estimate
-0.00
50
427
14
110
1.28
0.32
1.1
1.1
—
—
—
0
0
7
56
1.25
0.29
1.9
3.9
—
—
—
0
0
8
63
1.27
0.28
1.0
1.0
—
—
—
0
0
8
64
1.25
0.27
1.1
1.1
—
—
—
0
0
122
1290
0.93
0.27
1.6
1.7
1.32
1.34
mmol/l
0.11
110
1073
11
86
1.28
0.26
2.2
1.7
—
—
—
0
0
9
74
1.22
0.25
1.1
1.2
0.53
0.62
nmol/l
—
9
67
89
834
1.08
0.24
1.4
1.3
58.99
39.05
iu/ml
0.31
33
283
11
87
1.27
0.24
2.2
1.6
—
—
—
0
0
11
87
1.27
0.24
2.2
1.6
—
—
—
0
0
6
83
0.72
0.24
1.0
1.2
40.45
18.23
u/l
—
6
69
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
12
97
1.24
0.23
1.2
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
3.4
2.0
—
—
—
0
0
464
4580
1.07
0.23
4.8
4.6
4.65
4.71
mmol/l
0.51
433
4196
112
1063
1.07
0.22
5.4
4.5
1.01
1.02
kg/l
0.52
29
141
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
127
1212
1.06
0.21
2.9
2.6
330.79
7902.25
umol/l
5.71
109
1041
0
10
0.00
0.21
0.0
1.7
—
1.26
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
8
105
0.76
0.21
1.6
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
13
108
1.21
0.20
2.1
1.3
—
—
—
0
0
81
764
1.07
0.20
5.4
4.5
21.46
21.61
%
0.03
47
387
25
224
1.12
0.17
1.4
1.3
—
—
—
0
0
460
4553
1.05
0.16
4.8
4.5
1.50
1.53
mmol/l
0.76
425
4147
444
4392
1.05
0.16
6.8
6.0
40.68
40.14
mmol/mol
0.51
410
4037
11
92
1.20
0.16
1.9
1.5
—
—
—
0
0
97
1013
0.95
0.16
1.3
1.2
1.60
1.75
u/ml
0.05
20
273
29
317
0.91
0.15
1.6
1.8
—
—
—
0
0
12
102
1.18
0.15
1.5
1.3
—
—
—
0
0
12
102
1.18
0.15
1.5
1.3
—
—
—
0
0
16
140
1.15
0.15
2.0
1.4
—
—
—
0
0
9
81
1.11
0.15
1.6
1.5
—
—
—
0
0
43
402
1.08
0.14
3.5
2.8
77.09
62.64
ml/min/173m2
0.67
11
168
13
148
0.88
0.12
1.4
1.4
—
—
—
0
0
142
1460
0.96
0.12
3.0
3.1
7.02
6.76
mmol/l
0.26
120
1228
146
1500
0.96
0.12
3.6
3.8
4.22
6.79
mg/mmol
1.21
95
917
62
650
0.95
0.12
1.8
1.4
—
—
—
0
0
24
220
1.09
0.12
1.1
1.0
—
—
—
0
0
13
114
1.14
0.12
2.0
1.7
—
—
—
0
0
11
95
1.16
0.11
1.5
2.6
14.60
15.82
%
—
6
44
11
126
0.87
0.11
1.4
1.7
—
—
—
0
0
5
47
1.06
0.09
1.6
1.6
—
—
—
0
0
5
47
1.06
0.09
1.6
1.6
—
—
—
0
0
5
47
1.06
0.09
1.6
1.6
—
—
—
0
0
505
5074
0.96
0.08
31.0
21.8
4.41
4.42
e12/l
0.11
498
4922
461
4582
1.03
0.08
5.1
4.8
5.91
5.98
mmol/l
0.45
423
4137
505
5073
0.96
0.08
31.0
21.8
257.44
251.16
e9/l
1.20
498
4935
23
215
1.07
0.07
6.6
3.2
24.48
24.23
mmol/l
0.16
23
206
505
5072
0.97
0.07
30.8
21.8
39.25
39.62
%
0.63
475
4720
13
120
1.09
0.05
2.0
1.7
—
—
—
0
0
43
417
1.03
0.04
3.3
3.2
78.78
78.71
ng/l
0.00
38
368
32
310
1.03
0.03
1.2
1.2
139.72
153.68
iu/ml
0.09
11
131
441
4400
1.01
0.01
4.3
4.1
1.28
1.27
mmol/l
0.06
405
3975
27
264
1.02
0.00
1.6
1.6
—
—
—
0
0
43
424
1.02
0.00
2.7
2.3
27.03
33.96
u/l
0.94
36
353
53
526
1.01
0.00
3.2
4.0
11.53
15.91
ug/l
0.17
45
446
16
162
0.99
0.00
2.5
2.9
—
—
—
0
0
493
4934
0.99
0.00
13.3
10.6
26.18
24.40
u/l
0.61
478
4730
55
547
1.01
0.00
3.9
3.1
0.79
0.83
ug/l
0.18
40
378
44
442
1.00
0.00
2.2
2.0
0.22
0.21
g/l
0.06
38
417
12
119
1.01
0.00
2.3
2.2
8.87
60.88
ug/min
—
7
69
469
4692
1.00
0.00
5.4
5.2
2.73
2.74
mmol/l
0.08
435
4278
24
239
1.00
0.00
1.6
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
6
59
1.02
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
7.9
—
—
—
0
0
8
85
0.94
-0.00
2.5
1.6
—
—
—
0
0
6
60
1.00
-0.00
3.5
2.9
—
1071.17
—
0
6
6
65
0.92
-0.00
3.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
106.80
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
76
0.92
-0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
70
1.00
-0.00
1.3
1.6
—
—
—
0
0
5
52
0.96
-0.00
3.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MENINGES_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MENINGES_NOS | 1.849 [1.64, 2.08] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.382 |
During the follow-up period (1.1.1998 — 31.12.2019), 1164 out of 2919 females with CD2_BENIGN_MENINGES_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MENINGES_NOS | 1.959 [1.64, 2.35] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.033 |
During the follow-up period (1.1.1998 — 31.12.2019), 447 out of 1022 males with CD2_BENIGN_MENINGES_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MENINGES_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.178% | 0.389% |
| 5 | 0.971% | 2.184% |
| 10 | 2.724% | 5.914% |
| 15 | 5.12% | 10.892% |
| 20 | 9.169% | 19.39% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MENINGES_NOS – Beningn neoplasm: Meninges, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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