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Malignant immunoproliferative diseases

CD2_IMMUNOPROLIFERATIVE

lymphoma: A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C88
  • Cause of death: ICD-10 C88

2 out of 7 registries used, show all original rules.

319

4. Check minimum number of events

None

319

5. Include endpoints

None

319

6. Filter based on genotype QC (FinnGen only)

319

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
C81-C96
Name in latin
Morbi immunoproliferativi maligni

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 319 124 195
Unadjusted period prevalence (%) 0.07 0.04 0.09
Median age at first event (years) 67.83 65.99 69.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
293
Matched controls
2930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
+∞
256.5
207
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
48.9
131.9
163
73
XW000
NOMESCO Finland
Bone marrow biopsy
41.3
111.3
142
65
9761/3-C42.0
ICD-O-3
Waldenstrom macroglobulinemia of blood
+∞
86.9
79
*
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
81.9
67.3
74
12
C88.9
ICD-10 Finland
Malignant immunoproliferative disease, unspecified
+∞
63.9
59
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
50.5
45.3
54
13
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
21.8
38.5
57
32
L03AA02
ATC
filgrastim; parenteral
16.2
34.0
56
42
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.2
31.3
96
213
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
26.3
29.7
41
18
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
18.6
29.7
46
29
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.3
29.3
64
85
M04AA01
ATC
allopurinol; systemic
4.9
26.6
104
298
9671/3-C42.1
ICD-O-3
Lymphoplasmacytic lymphoma of bone marrow
+∞
26.4
25
*
A04AA01
ATC
ondansetron; systemic, rectal
7.0
24.9
66
117
C88.7
ICD-10 Finland
Other malignant immunoproliferative diseases
+∞
23.2
22
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
21.2
23.2
34
18
WW500
NOMESCO Finland
Blood transfusion
9.7
23.0
48
58
1512
Kela drug reimbursment
Ibrutinib
236.9
21.9
22
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
37.0
21.5
27
8
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
54.4
21.5
25
5
R50.9
ICD-10 Finland
Fever, unspecified
4.7
20.9
80
217
390
Kela drug reimbursment
Ibrutinib
118.5
20.9
22
*
L01AA02
ATC
chlorambucil; oral
59.2
19.2
22
*
JN4BD
NOMESCO Finland
Extensive body CT
4.0
17.5
78
242
1XC02
NOMESCO Finland
NA
37.5
16.9
21
6
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.9
16.9
43
71
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.6
16.7
40
60
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
179.7
16.7
17
*
L03AA13
ATC
pegfilgrastim; parenteral
8.1
16.3
37
51
L01EL01
ATC
ibrutinib; oral
+∞
15.8
15
*
ZX120
NOMESCO Finland
Intravenous
4.4
15.7
62
170
H02AB06
ATC
prednisolone; systemic
2.7
14.9
173
1020
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.8
14.5
42
82
J05AB11
ATC
valaciclovir; oral
3.8
14.0
64
200
J05AB01
ATC
aciclovir; systemic
3.2
13.9
87
345
C88.4
ICD-10 Finland
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lyphoma]
+∞
13.6
13
*
N08.1*C88.0
ICD-10 Finland
Glomerular disorders in Waldenström's macroglobulinaemia
+∞
13.6
13
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.7
13.3
64
208
JN4AD
NOMESCO Finland
Body CT examination
4.1
13.0
53
149
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
12.5
12.0
21
18
L01XE27
ATC
[U] ibrutinib; oral
67.7
11.7
13
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
11.6
63
223
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
11.4
170
1083
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
13.6
10.8
18
14
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
13.6
10.8
18
14
9591/3-C42.1
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of bone marrow
+∞
10.5
10
*
L01AA01
ATC
cyclophosphamide; systemic
33.9
10.4
13
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
10.4
93
449
B03XA01
ATC
erythropoietin; parenteral
19.7
10.4
15
8
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
15.3
10.1
16
11
C83.1
ICD-10 Finland
Mantle cell lymphoma
17.5
10.0
15
9
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
9.8
38
102
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
9.7
108
582
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
15.7
9.6
15
10
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
31.1
9.5
12
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.1
9.3
22
33
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
37.9
9.1
11
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
19.3
9.0
13
7
C90.0
ICD-10 Finland
Multiple myeloma
11.2
8.9
16
15
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
51.5
8.7
10
*
JN6AD
NOMESCO Finland
CT of torso and neck
12.1
8.7
15
13
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
13.3
8.5
14
11
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
12.2
8.2
14
12
127
Kela drug reimbursment
Transplant complication
12.2
8.2
14
12
J01MA14
ATC
moxifloxacin; systemic
3.2
7.9
41
140
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
7.9
97
538
WW200
NOMESCO Finland
Immunization
6.2
7.8
20
34
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
7.8
82
420
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.8
7.8
17
23
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
46.2
7.8
9
*
J01MA12
ATC
levofloxacin; systemic
2.3
7.7
76
381
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
12.3
7.6
13
11
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
10.4
7.6
14
14
H02AB02
ATC
dexamethasone; systemic
2.8
7.5
50
202
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
82.1
7.4
8
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
7.1
7.4
17
25
D70.82
ICD-10 Finland
Drug-induced neutropenia
7.1
7.4
17
25
B03XA02
ATC
darbepoetin alfa; parenteral
6.5
7.4
18
29
L03AA14
ATC
lipegfilgrastim; parenteral
6.9
7.2
17
26
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
20.6
7.2
10
5
TAB00
NOMESCO Finland
Lumbar puncture
5.2
7.1
21
43
A41.9
ICD-10 Finland
Sepsis, unspecified
4.4
7.0
24
58
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.3
6.9
24
59
L04AA06
ATC
mycophenolic acid; systemic
11.3
6.9
12
11
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
17.2
6.8
10
6
WW300
NOMESCO Finland
Transfer of autologic stem cells
41.0
6.8
8
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
14.7
6.4
10
7
UJF32
NOMESCO Finland
Coloscopy
2.0
6.3
90
525
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
6.3
6
*
C88.3
ICD-10 Finland
Immunoproliferative small intestinal disease
+∞
6.3
6
*
9689/3-C42.2
ICD-O-3
Splenic marginal zone B-cell lymphoma of spleen
+∞
6.3
6
*
A02BC02
ATC
pantoprazole; systemic
1.9
6.2
196
1512
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.0
6.2
104
643

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
208
178
31.71
228.95
12.5
1.4
13.7
1.1
g/l
28.53
199
159
154
67
43.50
227.43
2.1
1.5
—
—
—
0
0
160
97
32.09
206.04
7.4
3.1
8.2
2.8
ratio
—
7
9
161
99
31.82
206.03
7.4
3.2
110.8
129.6
mg/l
0.11
135
81
161
99
31.82
206.03
7.4
3.3
29.7
38.0
mg/l
0.82
136
82
140
68
35.91
196.85
7.0
3.8
—
—
—
0
0
203
217
23.98
193.45
11.1
2.0
—
—
—
0
0
105
43
35.91
155.17
1.5
1.2
—
—
—
0
0
178
218
17.21
151.27
6.1
2.2
7.8
9.9
g/l
4.94
173
195
107
66
23.89
133.12
1.6
1.7
—
—
—
0
0
130
128
16.45
125.09
10.0
1.8
3.9
3.7
g/l
0.27
84
92
118
117
15.42
112.20
10.2
1.8
15.2
10.3
g/l
4.22
95
101
70
32
27.74
97.66
1.9
2.5
—
—
—
0
0
67
38
22.05
85.07
1.1
1.1
—
—
—
0
0
170
378
8.49
82.77
5.9
2.8
1.7
1.8
%
1.10
160
343
92
103
12.15
79.02
10.7
1.8
37.5
36.7
g/l
0.45
80
89
142
282
8.27
76.08
5.4
2.8
65.3
68.3
e9/l
0.37
118
217
105
148
10.08
75.71
2.9
2.3
1.5
1.5
g/l
0.33
92
128
139
278
8.09
73.72
1.9
1.6
—
—
—
0
0
126
232
8.32
71.98
2.0
1.5
—
—
—
0
0
99
146
9.38
68.34
1.5
1.5
—
—
—
0
0
121
229
7.90
66.92
2.0
1.5
—
—
—
0
0
43
14
35.34
66.59
1.4
1.4
—
—
—
0
0
61
0
+∞
65.96
2.9
0.0
1.9
—
mpas
—
46
0
163
462
6.17
58.44
4.0
1.3
1.3
2.7
g/l
11.57
144
272
198
732
5.49
50.32
7.3
3.1
1564.9
9335.3
umol/l
2.50
189
625
218
885
5.62
49.01
15.8
5.8
—
—
—
0
0
44
33
15.31
47.75
3.0
1.9
1.3
1.3
e9/l
0.04
27
16
251
1193
6.18
45.21
14.5
5.9
54.8
58.1
%
3.54
244
1120
260
1275
6.62
45.04
14.8
5.8
0.6
0.6
e9/l
1.44
241
1099
264
1316
6.84
44.71
16.2
5.9
0.2
0.2
e9/l
1.70
249
1152
260
1281
6.57
44.60
14.8
5.8
0.0
0.0
e9/l
0.22
241
1112
262
1302
6.67
44.40
14.9
5.9
1.9
1.9
e9/l
0.02
247
1146
98
225
5.84
42.84
7.5
4.2
0.8
0.9
%
0.12
62
82
101
240
5.69
42.46
2.0
1.4
—
—
—
0
0
128
383
4.91
40.76
12.3
6.0
1.1
1.0
mmol/l
0.51
122
352
35
23
16.97
40.58
1.7
2.1
13.0
12.9
%
—
7
12
269
1484
6.18
36.88
28.3
9.3
3.4
4.2
e9/l
12.04
250
1307
84
198
5.40
35.12
8.1
4.1
0.5
0.3
%
0.41
40
61
86
208
5.29
34.89
8.0
4.4
0.0
0.1
%
1.58
55
74
256
1400
5.20
34.29
19.5
7.2
1.2
1.2
mmol/l
0.52
219
1181
235
1224
4.49
33.17
10.3
4.8
33.2
35.1
g/l
4.61
230
1149
41
49
9.45
32.48
6.0
4.2
1.5
1.0
%
0.38
32
41
28
20
15.25
30.88
1.3
1.5
—
—
—
0
0
33
35
10.40
28.44
1.7
1.1
—
—
—
0
0
182
877
3.50
26.95
13.8
4.3
7.4
7.4
ph
0.49
44
160
73
195
4.56
25.72
7.9
4.5
0.0
0.1
%
0.44
43
65
123
488
3.47
24.46
8.8
3.7
0.8
0.8
mmol/l
0.60
118
460
155
717
3.26
23.80
2.8
2.1
3.2
3.1
mg/l
0.16
137
617
29
34
9.28
23.13
2.4
2.1
33.4
32.8
pg
0.34
29
34
117
473
3.33
22.25
3.7
2.5
11.6
12.7
umol/l
0.88
112
432
119
489
3.29
21.99
4.7
2.0
31.4
29.7
s
1.50
113
472
107
416
3.37
21.61
4.1
2.5
24.2
22.4
%
0.55
97
364
33
50
7.25
21.28
2.1
1.7
—
—
—
0
0
25
27
9.96
21.14
4.2
2.0
328.8
708.4
e6/l
0.88
16
11
188
1021
3.05
21.05
4.9
2.7
222.0
153.4
ug/l
1.67
180
924
27
9
32.60
20.92
1.5
1.7
—
—
—
0
0
119
508
3.14
20.38
12.3
5.2
—
—
—
0
0
22
21
11.18
20.22
2.7
3.0
35.3
39.0
%
—
7
6
26
33
8.49
19.43
7.6
3.2
53.9
57.8
%
0.28
18
26
160
828
2.87
19.04
11.1
4.5
—
—
—
0
0
24
9
28.68
18.09
1.3
2.7
—
—
—
0
0
33
63
5.73
16.94
1.8
1.3
—
—
—
0
0
167
926
2.69
16.77
6.5
3.3
2.3
2.3
mmol/l
0.22
150
813
26
40
6.99
16.46
1.4
1.4
—
—
—
0
0
22
28
8.37
16.35
1.2
1.2
—
—
—
0
0
26
41
6.82
16.09
9.3
4.4
—
—
—
0
0
22
29
8.07
15.89
2.6
2.4
—
—
—
0
0
28
50
6.04
15.36
1.5
1.3
8.4
24.2
e6/l
0.50
20
37
28
50
6.04
15.36
1.6
1.4
146.1
2441.0
e6/l
0.50
20
39
185
1135
2.50
14.27
25.6
10.2
0.0
0.0
e9/l
0.28
163
937
35
82
4.67
14.23
1.4
1.4
—
—
—
0
0
23
38
6.45
13.59
1.3
1.2
—
—
—
0
0
76
312
2.88
13.30
1.4
1.3
220.0
486.3
titre
—
8
70
37
96
4.23
13.21
2.1
3.2
1.4
0.2
g/l
0.56
21
39
115
590
2.48
12.83
1.9
1.7
1161.6
1211.9
nmol/l
0.20
90
452
26
52
5.35
12.65
5.7
3.0
53.5
59.2
%
0.95
26
52
24
45
5.69
12.50
1.9
1.2
262.3
331.4
u/ml
0.28
15
23
21
35
6.35
12.29
2.6
1.8
—
—
—
0
0
21
35
6.35
12.29
2.6
1.8
—
—
—
0
0
21
35
6.35
12.29
2.6
1.8
—
—
—
0
0
21
35
6.35
12.29
2.6
1.8
—
—
—
0
0
25
50
5.34
12.15
4.6
2.4
2.8
4.8
e9/l
4.71
25
50
12
10
12.43
11.80
1.5
1.3
—
—
—
0
0
258
1935
2.74
11.75
8.1
4.3
45.8
13.6
mm/h
27.06
245
1763
120
656
2.33
11.37
21.2
6.7
—
—
—
0
0
145
859
2.26
11.33
6.3
2.5
—
—
—
0
0
183
1201
2.23
11.01
7.9
4.2
—
—
—
0
0
20
36
5.86
10.84
1.1
1.1
—
—
—
0
0
88
427
2.47
10.83
2.5
2.0
—
—
—
0
0
120
678
2.23
10.32
9.2
4.4
84.1
86.2
%
0.40
114
670
14
19
7.66
9.78
1.9
1.6
—
—
—
0
0
53
218
2.72
9.05
4.8
4.1
98.0
88.0
ng/l
0.27
47
195
100
560
2.14
8.53
4.9
3.1
2.5
2.5
mmol/l
2.97
90
496
17
33
5.39
8.50
1.8
1.4
—
—
—
0
0
12
16
7.75
8.47
1.8
1.1
—
—
—
0
0
126
774
2.04
8.37
4.7
3.5
—
—
—
0
0
120
726
2.05
8.30
2.0
1.6
22.3
20.7
nmol/l
0.38
109
609
13
9
14.99
8.27
1.0
1.0
—
—
—
0
0
152
1003
1.98
8.21
5.4
4.2
76.8
85.1
e6/l
0.08
121
736
233
1788
2.12
8.17
5.8
4.4
—
—
—
0
0
138
884
1.99
8.08
4.8
3.6
30.8
140.0
e6/l
0.84
118
690
17
35
5.07
7.98
1.1
1.0
—
—
—
0
0
10
12
8.57
7.62
3.8
1.3
—
—
—
0
0
12
9
13.79
7.44
1.1
1.1
—
—
—
0
0
172
1212
1.91
7.39
11.2
10.1
1.2
1.3
inr
0.42
51
317
14
26
5.59
7.31
1.3
1.2
—
—
—
0
0
165
1156
1.89
7.13
2.6
2.1
93.7
91.2
pmol/l
0.23
106
601
19
48
4.15
6.99
1.1
1.8
—
—
—
0
0
125
807
1.90
6.91
4.8
3.5
0.7
0.4
e6/l
0.47
106
610
11
17
6.67
6.82
1.3
1.3
—
—
—
0
0
102
621
1.94
6.69
3.7
2.7
3.2
4.1
e6/l
0.89
91
548
96
573
1.97
6.66
3.2
1.8
2.4
1.4
mg/l
0.53
83
452
126
826
1.87
6.57
3.4
3.4
—
—
—
0
0
64
338
2.12
6.17
2.3
1.5
—
—
—
0
0
96
587
1.91
6.14
4.1
3.0
512.1
565.4
mosm/kgh2o
2.15
82
494
19
54
3.68
5.98
5.0
3.4
—
—
—
0
0
36
152
2.54
5.80
2.5
2.6
—
—
—
0
0
15
37
4.20
5.69
1.9
1.3
739.9
1777.2
e6/l
—
10
25
52
263
2.17
5.58
15.2
11.1
—
—
—
0
0
17
47
3.76
5.56
2.7
3.0
—
—
—
0
0
48
237
2.21
5.46
14.0
3.9
1.2
1.2
mmol/l
0.21
48
205
93
583
1.84
5.42
3.9
4.0
1110.8
254.2
ng/l
0.52
79
497
9
8
11.53
5.32
1.7
1.6
—
—
—
0
0
65
369
1.96
5.10
1.3
1.2
—
—
—
0
0
10
19
5.40
5.07
1.0
1.1
—
—
—
0
0
14
37
3.91
4.86
2.4
1.7
—
—
—
0
0
59
330
1.97
4.82
2.0
1.7
—
—
—
0
0
139
1005
1.68
4.81
2.4
2.2
—
—
—
0
0
8
7
11.68
4.81
6.3
7.3
—
—
—
0
0
54
293
2.01
4.80
11.7
4.2
2.6
1.8
mmol/l
0.81
44
236
12
29
4.26
4.67
1.3
1.2
—
—
—
0
0
50
267
2.03
4.64
10.6
4.1
—
—
—
0
0
50
268
2.03
4.60
3.0
2.2
0.2
0.2
g/l
4.10
42
246
42
213
2.12
4.47
8.5
4.9
7.4
7.4
ph
—
9
19
34
159
2.27
4.40
3.7
2.6
3.2
4.1
e9/l
1.14
21
113
16
50
3.32
4.40
5.6
2.9
—
—
—
0
0
9
12
7.68
4.38
4.0
2.8
2234.4
2408.3
ml
—
9
12
9
13
7.09
4.19
1.6
1.2
—
—
—
0
0
94
633
1.69
4.15
1.5
1.3
—
—
—
0
0
55
316
1.89
4.14
2.8
4.0
9.3
42.0
ug/l
0.70
39
269
12
32
3.86
4.12
2.0
1.3
—
—
—
0
0
64
391
1.80
3.96
1.4
1.3
56.6
36.2
iu/ml
0.24
16
126
119
861
1.61
3.93
3.9
2.4
57.8
58.0
u/l
0.02
112
796
7
8
8.91
3.79
1.3
1.0
—
—
—
0
0
15
50
3.10
3.74
2.9
2.7
—
—
—
0
0
7
9
7.92
3.57
1.4
1.7
—
—
—
0
0
59
365
1.76
3.49
1.3
1.3
0.9
14.4
u/ml
2.45
17
134
16
58
2.85
3.47
3.9
2.7
—
—
—
0
0
160
1265
1.53
3.47
4.7
3.9
0.0
0.0
estimate
0.00
34
241
146
1135
1.53
3.40
5.6
4.3
49.8
43.1
ng/l
0.20
118
877
9
18
5.11
3.39
1.2
1.1
—
—
—
0
0
10
27
3.79
3.38
1.2
1.0
—
—
—
0
0
7
10
7.13
3.38
1.0
1.3
—
—
—
0
0
7
10
7.13
3.38
1.7
1.9
—
—
—
0
0
17
65
2.71
3.36
3.7
2.4
118.6
126.0
g/l
0.39
12
46
278
2514
1.82
3.25
47.3
17.0
23.7
25.5
mg/l
0.48
262
2045
159
1268
1.51
3.23
6.3
5.2
0.0
0.0
estimate
0.00
33
240
161
1288
1.50
3.22
4.7
3.9
0.0
0.0
estimate
0.00
33
229
9
20
4.60
3.13
2.4
2.1
—
—
—
0
0
9
20
4.60
3.13
1.0
1.0
—
—
—
0
0
46
274
1.79
3.09
14.2
9.4
1.5
1.4
mmol/l
0.34
46
260
6
8
7.62
3.06
2.3
8.4
42.8
38.8
%
—
6
8
19
83
2.37
2.90
10.4
5.3
8.7
8.1
kpa
0.57
19
75
5
6
8.44
2.76
1.2
1.3
—
—
—
0
0
5
7
7.23
2.56
1.2
1.3
—
—
—
0
0
40
244
1.73
2.49
2.6
1.9
329.1
384.1
nmol/l
1.06
40
221
242
2161
1.50
2.45
44.1
18.8
34.9
39.1
%
6.38
156
1424
11
40
2.81
2.40
1.0
1.1
—
—
—
0
0
54
363
1.59
2.33
10.8
8.8
1.1
1.2
mmol/l
0.08
43
285
36
218
1.73
2.31
1.5
1.6
—
—
—
0
0
5
9
5.62
2.22
17.8
7.8
—
—
—
0
0
109
855
1.42
2.22
2.1
2.1
97.2
231.6
u/l
4.95
102
801
18
87
2.13
2.21
3.5
3.7
—
—
—
0
0
7
19
3.74
2.16
1.0
1.1
—
—
—
0
0
7
19
3.74
2.16
1.0
1.1
—
—
—
0
0
80
599
1.45
2.08
4.8
3.8
—
—
—
0
0
5
10
5.06
2.08
7.0
4.7
—
—
—
0
0
24
134
1.86
2.01
1.7
1.3
—
—
—
0
0
28
166
1.75
1.95
10.0
5.1
—
—
—
0
0
5
11
4.60
1.95
4.0
1.6
—
—
—
0
0
34
216
1.64
1.86
6.0
4.3
—
—
—
0
0
5
12
4.21
1.83
3.2
1.5
2.5
1.5
umol/l
—
5
12
34
219
1.62
1.77
6.0
3.9
—
—
—
0
0
6
19
3.20
1.67
2.0
1.0
—
—
—
0
0
7
25
2.84
1.66
1.1
1.4
—
—
—
0
0
47
332
1.49
1.64
1.4
1.3
—
—
—
0
0
40
273
1.53
1.64
2.4
2.8
15.9
7.4
ug/l
0.38
34
239
36
243
1.54
1.56
4.7
3.5
—
—
—
0
0
7
27
2.63
1.52
1.1
1.4
0.6
0.5
nmol/l
—
7
22
12
59
2.07
1.45
1.3
1.3
—
—
—
0
0
102
841
1.31
1.44
5.1
4.4
—
—
—
0
0
205
1853
1.30
1.42
3.9
3.7
14.7
15.0
pmol/l
1.09
180
1635
35
240
1.51
1.42
1.7
2.2
189.2
151.4
ug/g
0.23
25
194
26
167
1.61
1.39
15.3
13.2
24.3
24.5
mmol/l
0.14
26
155
6
24
2.53
1.31
1.0
1.4
—
—
nmol/l
—
0
0
6
24
2.53
1.31
1.2
1.0
854.3
548.1
ng/l
—
6
13
6
24
2.53
1.31
1.2
1.0
272.8
256.7
ng/l
—
6
12
8
36
2.25
1.25
2.3
3.1
—
—
—
0
0
14
79
1.81
1.19
1.7
1.2
—
—
—
0
0
23
151
1.56
1.15
4.2
3.4
25.2
24.8
mmol/l
0.19
23
146
15
88
1.74
1.13
1.7
1.6
—
—
—
0
0
27
186
1.49
1.10
3.3
3.0
—
—
—
0
0
7
32
2.21
1.08
1.9
1.3
—
—
—
0
0
278
2657
1.36
1.05
47.5
20.3
92.6
83.2
umol/l
1.44
278
2657
24
164
1.50
1.02
14.8
12.6
—
—
—
0
0
82
688
1.26
0.99
4.1
3.6
—
—
—
0
0
5
23
2.19
0.98
1.0
1.3
—
—
—
0
0
7
36
1.97
0.97
2.6
2.6
2.8
8.2
nmol/l
—
7
36
7
36
1.97
0.97
3.1
8.3
6.3
6.3
mmol/l
—
7
30
6
27
2.24
0.94
2.3
3.2
—
—
—
0
0
6
27
2.24
0.94
1.8
2.0
—
—
—
0
0
6
27
2.24
0.94
1.7
1.3
—
—
—
0
0
52
415
1.30
0.93
30.3
26.0
1.1
1.3
inr
—
8
51
228
2411
0.81
0.92
5.9
6.5
39.5
40.9
mmol/mol
1.79
207
2217
7
127
0.54
0.90
1.4
1.5
—
—
—
0
0
6
30
2.02
0.87
1.0
1.3
—
—
—
0
0
56
679
0.79
0.86
1.9
1.7
1.3
1.3
mmol/l
0.01
50
558
38
293
1.34
0.86
1.3
1.3
—
—
—
0
0
138
1240
1.20
0.85
4.5
5.3
1.7
2.8
ug/l
2.16
119
1108
73
617
1.24
0.83
1.6
1.8
464.8
444.1
pmol/l
0.25
58
506
97
848
1.21
0.79
5.7
3.3
9903.6
203.4
mg/l
5.19
79
561
14
90
1.58
0.79
3.2
4.7
—
—
—
0
0
18
124
1.48
0.77
5.1
4.4
—
—
—
0
0
20
141
1.45
0.76
1.8
3.1
—
—
—
0
0
7
39
1.81
0.73
2.4
1.8
90.2
89.2
%
—
7
39
67
781
0.82
0.73
3.0
3.2
—
—
—
0
0
18
126
1.45
0.72
1.2
1.3
—
—
—
0
0
5
27
1.86
0.68
1.2
2.3
—
—
—
0
0
268
2583
1.23
0.68
35.2
15.8
—
—
—
0
0
7
43
1.64
0.67
1.3
1.1
9.8
8.1
u/l
—
7
35
5
28
1.80
0.66
31.4
3.8
7.7
11.3
%
—
5
28
198
1863
1.17
0.64
5.7
4.4
—
—
—
0
0
20
148
1.37
0.61
3.4
3.8
—
—
—
0
0
8
51
1.58
0.61
1.1
1.5
—
—
—
0
0
8
54
1.49
0.57
2.6
2.4
—
—
—
0
0
57
491
1.20
0.55
1.4
1.2
0.5
1.1
u/ml
—
8
125
21
161
1.33
0.53
1.2
1.2
—
—
—
0
0
79
708
1.15
0.48
5.9
4.2
0.0
0.0
estimate
0.00
29
233
238
2461
0.87
0.47
4.3
4.8
4.1
4.5
mmol/l
4.43
216
2235
238
2295
1.15
0.46
4.6
4.5
2.0
2.0
mu/l
0.08
217
2044
11
77
1.44
0.46
23.9
3.3
—
—
—
0
0
237
2445
0.88
0.42
4.3
4.8
1.4
1.4
mmol/l
1.19
213
2205
279
2732
1.17
0.37
64.5
24.7
233.5
239.7
e9/l
0.61
274
2663
8
115
0.69
0.37
1.6
1.3
—
—
—
0
0
19
234
0.80
0.37
1.6
1.5
—
—
—
0
0
246
2526
0.89
0.37
4.7
5.5
2.3
2.6
mmol/l
6.28
223
2278
279
2733
1.17
0.37
64.6
24.7
6.7
6.9
e9/l
0.35
272
2655
279
2733
1.17
0.37
64.5
24.7
4.0
4.5
e12/l
29.84
272
2653
6
41
1.47
0.36
1.0
1.5
—
—
—
0
0
62
559
1.14
0.36
5.3
4.3
1.0
1.0
kg/l
—
10
86
5
79
0.63
0.36
1.0
1.1
—
—
—
0
0
13
100
1.31
0.34
2.3
1.9
—
—
—
0
0
6
46
1.31
0.33
4.3
2.8
—
—
—
0
0
232
2371
0.92
0.24
4.1
4.3
1.2
1.3
mmol/l
1.13
206
2124
5
41
1.22
0.22
1.8
1.6
34.0
17.0
ug/l
—
5
41
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
4.0
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
94
899
1.06
0.17
4.0
4.1
17.3
8.7
mg/mmol
0.67
63
581
205
2009
1.06
0.16
57.0
22.8
329.1
332.0
g/l
4.01
205
2000
24
218
1.11
0.14
1.9
2.2
11.9
12.7
nmol/l
0.21
24
192
5
61
0.82
0.08
1.6
1.8
—
—
—
0
0
89
867
1.04
0.08
3.4
3.2
6.7
7.3
mmol/l
0.71
77
708
22
205
1.08
0.08
1.4
1.5
—
—
—
0
0
8
90
0.89
0.07
1.3
1.1
—
—
—
0
0
12
109
1.10
0.06
1.0
1.2
26.0
146.4
iu/ml
—
5
38
73
713
1.03
0.05
2.9
3.1
0.7
0.8
ug/l
0.66
50
497
248
2482
1.00
0.00
5.0
5.1
6.0
6.1
mmol/l
0.85
218
2239
14
144
0.97
0.00
1.3
1.2
—
—
—
0
0
5
53
0.94
0.00
1.2
1.2
—
—
—
0
0
7
75
0.93
0.00
2.0
1.7
35.3
45.6
nmol/l
—
7
70
8
84
0.95
0.00
1.4
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
0.00
32.8
2.7
56.4
66.2
%
—
6
61
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
7.6
—
1401.1
—
0
8
0
8
0.00
0.00
0.0
1.0
—
150.5
—
0
8
0
5
0.00
0.00
0.0
2.2
—
0.8
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
5.4
—
980.9
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_IMMUNOPROLIFERATIVE – Malignant immunoproliferative diseases

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).