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Carcinoma in situ of cervix uteri, endocervix

CD2_INSITU_CERVIX_UTERI_ENDOCERVIX_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06.0&
  • Cause of death: ICD-10 D06.0&

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D06
Name in latin
Carcinoma in situ endocervicis (uteri)

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 438 438 -
Unadjusted period prevalence (%) 0.15 0.15 -
Median age at first event (years) 38.86 38.86 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
381
Matched controls
3809
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
+∞
323.0
381
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
60.7
222.4
273
152
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
31.9
181.8
302
407
ULA02
NOMESCO Finland
Kolposcopy
31.4
180.6
299
396
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
+∞
143.0
128
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
17.9
134.4
269
450
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
15.7
112.2
215
290
LDA10
NOMESCO Finland
Curettage of cervix uteri
17.3
94.0
161
154
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
24.2
85.8
126
76
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
34.8
75.8
99
38
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
155.0
72.9
75
6
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
191.6
63.1
64
*
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
+∞
38.2
36
*
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
327.0
30.3
30
*
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
9.2
29.1
63
80
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
+∞
27.4
26
*
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
9.7
26.4
55
65
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
+∞
26.4
25
*
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
+∞
25.3
24
*
LEB00
NOMESCO Finland
Biopsy of vagina
15.3
24.2
40
29
N87.1
ICD-10 Finland
Moderate cervical dysplasia
7.9
22.6
53
76
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
22.1
21
*
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
10.5
20.4
40
42
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
8.6
20.0
44
57
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.7
19.3
217
1251
ZXC00
NOMESCO Finland
Use of diathermy
29.6
19.0
25
9
LCA06
NOMESCO Finland
Biopsy of endometrium
3.4
18.2
101
363
115
Kela drug reimbursment
Breast cancer
+∞
16.8
16
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.0
16.1
34
41
H02AB02
ATC
dexamethasone; systemic
16.6
15.9
25
16
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
62.8
15.9
18
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
15.7
15
*
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
+∞
15.7
15
*
LCD10
NOMESCO Finland
Vaginal hysterectomy
6.5
15.7
41
69
PJA12
NOMESCO Finland
Sentinel node biopsy
47.0
15.2
18
*
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
83.4
14.7
16
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
14.7
14
*
WX402
NOMESCO Finland
General anaesthesia
3.2
14.7
86
319
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
13.6
13
*
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
+∞
13.6
13
*
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
20.9
12.6
18
9
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
+∞
12.6
12
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
134.2
12.5
13
*
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
134.2
12.5
13
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.7
12.3
99
443
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
+∞
11.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
11.5
11
*
B01AB10
ATC
tinzaparin; parenteral
5.7
11.3
32
60
ZXC96
NOMESCO Finland
Robot assisted procedure
18.5
10.8
16
9
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
22.2
10.8
15
7
130
Kela drug reimbursment
Malignant tumour
+∞
10.5
10
*
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
+∞
10.5
10
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
10.5
10
*
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
+∞
10.5
10
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
4.7
10.3
35
81
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
7.0
10.1
24
36
B01AB05
ATC
enoxaparin; parenteral
2.3
9.9
105
538
C539, 6666, 0
ICD-O-3
NA
7.1
9.8
23
34
A63.0
ICD-10 Finland
Anogenital (venereal) warts
3.8
9.7
41
117
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
56.5
9.7
11
*
XX3DW
NOMESCO Finland
Time consuming IT work
4.5
9.6
33
78
A04AA55
ATC
palonosetron, combinations; systemic
+∞
9.4
9
*
8140/3-C53.0
ICD-O-3
Adenocarcinoma, NOS, of endocervix
+∞
9.4
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
9.4
9
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
16.1
9.1
14
9
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
8.8
49
171
HAC20
NOMESCO Finland
Total mastectomy
51.2
8.7
10
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
7.0
8.5
20
30
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
+∞
8.4
8
*
8076/3-C53.9
ICD-O-3
Squamous cell carcinoma, microinvasive of cervix uteri
+∞
8.4
8
*
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
3.9
8.3
33
90
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
6.0
7.6
20
35
WF002
NOMESCO Finland
Radical radiotherapy
25.6
7.6
10
*
JN4BD
NOMESCO Finland
Extensive body CT
5.2
7.5
22
44
L02BA01
ATC
tamoxifen; oral
81.6
7.4
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
81.6
7.4
8
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
81.6
7.4
8
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
7.3
7
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
4.9
6.8
21
45
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
8.9
6.6
13
15
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
71.0
6.4
7
*
G01AA10
ATC
clindamycin; vaginal
1.9
6.4
107
646
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
Z51.5
ICD-10 Finland
Palliative care
27.2
6.3
8
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.1
6.1
32
110

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
96
102
11.77
84.51
1.4
1.3
—
—
—
0
0
85
128
8.00
56.06
3.1
1.7
—
—
—
0
0
26
20
13.76
27.35
1.0
1.0
—
—
—
0
0
261
1469
2.92
26.39
2.9
1.7
—
—
—
0
0
66
254
2.88
12.63
1.8
1.5
21.4
28.0
u/ml
0.56
61
245
232
1624
1.91
9.99
3.7
3.8
—
—
—
0
0
153
987
1.85
8.08
1.8
1.8
—
—
—
0
0
12
8
15.37
7.75
1.1
1.1
—
—
—
0
0
166
1139
1.74
6.90
3.5
3.9
36.8
37.2
g/l
0.48
153
1052
68
349
2.12
6.87
1.3
1.1
—
—
—
0
0
58
301
2.07
5.68
3.4
3.0
—
—
—
0
0
232
1829
1.57
5.11
4.3
4.1
0.0
0.0
estimate
0.50
63
343
233
1850
1.55
4.89
3.2
3.0
0.0
0.0
estimate
0.50
62
333
200
1545
1.54
4.69
7.9
6.8
0.0
0.0
e9/l
0.00
172
1271
144
1091
1.48
3.47
3.2
2.5
—
—
—
0
0
390
3608
1.74
3.29
9.6
9.0
3.9
3.9
mmol/l
0.22
380
3494
388
3602
1.68
3.00
9.6
9.0
139.6
139.6
mmol/l
0.06
379
3500
77
527
1.56
2.96
3.1
3.4
—
—
—
0
0
35
193
1.88
2.94
3.1
2.1
1.2
1.2
mmol/l
0.56
28
158
106
784
1.46
2.83
2.5
2.4
0.3
0.4
e6/l
0.30
82
569
115
871
1.43
2.70
2.5
2.5
167.9
90.5
e6/l
0.23
88
644
216
1827
1.36
2.60
3.1
2.9
0.0
0.0
estimate
0.50
62
340
208
1750
1.36
2.58
3.4
4.0
6.4
6.3
mmol/l
0.31
199
1556
147
1171
1.38
2.57
1.6
1.7
—
—
—
0
0
123
952
1.41
2.54
3.2
2.0
2.3
2.3
mmol/l
0.60
115
842
193
1608
1.36
2.54
6.0
5.5
0.7
0.7
%
0.10
188
1484
25
132
1.95
2.41
1.2
1.3
—
—
—
0
0
12
46
2.65
2.38
4.3
2.4
5.1
5.0
kpa
0.21
12
46
12
46
2.65
2.38
4.3
2.4
2.7
2.4
mmol/l
—
7
32
12
46
2.65
2.38
4.3
2.4
9.4
9.2
kpa
0.13
12
46
135
1075
1.37
2.33
5.7
5.5
—
—
—
0
0
118
927
1.37
2.21
3.3
3.2
0.0
0.0
estimate
0.80
63
344
433
4231
3.05
2.19
15.7
13.8
269.5
269.0
e9/l
0.05
426
4155
164
1360
1.33
2.14
5.4
5.2
1.2
1.2
mmol/l
0.34
128
1162
209
1794
1.32
2.14
5.7
5.4
0.5
0.5
e9/l
0.28
191
1592
210
1806
1.31
2.11
5.7
5.4
0.0
0.0
e9/l
0.31
191
1596
196
1670
1.31
2.11
6.1
5.4
2.7
2.7
%
0.08
191
1548
5
10
5.04
2.07
1.2
2.8
1686.0
2428.0
ml
—
5
10
93
710
1.39
2.06
2.6
2.7
—
—
—
0
0
114
903
1.35
2.01
4.1
5.2
1.0
1.1
inr
3.44
45
312
196
1682
1.30
1.96
6.3
5.6
8.2
7.7
%
1.44
191
1571
394
3742
1.53
1.93
9.9
9.0
21.6
17.2
mg/l
1.82
314
2799
143
1181
1.31
1.89
4.9
4.7
1.2
1.2
mmol/l
0.33
124
1069
7
22
3.22
1.88
2.6
2.3
—
—
—
0
0
7
22
3.22
1.88
2.6
2.3
3.9
4.1
mmol/l
—
7
22
7
22
3.22
1.88
2.6
2.3
106.4
106.4
mmol/l
—
7
22
282
2550
1.30
1.84
3.8
3.7
—
—
—
0
0
169
1432
1.29
1.84
2.7
2.8
—
—
—
0
0
74
556
1.40
1.80
2.7
2.2
548.1
533.3
mosm/kgh2o
0.23
64
466
100
791
1.34
1.77
2.5
2.4
—
—
—
0
0
19
103
1.88
1.74
2.8
9.3
—
—
—
0
0
214
1884
1.27
1.67
5.7
5.6
0.2
0.2
e9/l
0.33
194
1705
200
1748
1.27
1.66
6.1
5.4
29.3
29.9
%
0.43
193
1625
136
1137
1.28
1.61
2.8
2.9
198.2
62.3
e6/l
0.76
98
710
221
1959
1.26
1.61
8.7
6.4
3.7
4.0
e9/l
1.65
205
1723
98
785
1.32
1.59
3.3
2.8
7.4
7.4
ph
0.32
26
133
198
1736
1.26
1.57
6.0
5.2
55.5
56.7
%
0.83
193
1620
6
21
2.88
1.51
1.0
1.1
1308.0
1707.9
miu/ml
—
6
21
13
65
2.03
1.50
3.5
2.2
1.4
1.3
mg/l
0.15
13
60
210
1862
1.25
1.49
5.8
5.4
1.9
2.0
e9/l
0.37
194
1690
60
452
1.38
1.45
2.4
1.7
2.4
2.4
mmol/l
0.63
53
384
171
1485
1.25
1.45
5.6
3.4
8.7
9.7
umol/l
1.12
166
1374
12
59
2.06
1.45
3.3
2.3
—
—
—
0
0
20
118
1.73
1.44
3.9
6.6
24.5
24.4
mmol/l
0.04
20
118
32
215
1.53
1.40
7.2
9.3
-0.0
0.8
mmol/l
0.53
25
162
30
435
0.67
1.34
1.7
1.7
—
—
—
0
0
17
99
1.75
1.29
10.3
14.5
—
—
—
0
0
19
297
0.62
1.21
1.2
1.6
203.4
323.2
mu/l
3.18
14
265
32
223
1.47
1.20
5.1
4.0
0.4
0.8
%
—
5
34
35
249
1.44
1.19
3.6
3.0
—
—
—
0
0
59
465
1.31
1.10
1.3
1.3
31.8
26.5
iu/l
0.48
50
409
75
613
1.27
1.06
2.2
2.2
8.6
10.0
e6/l
0.28
66
535
268
2492
1.19
1.03
7.1
5.0
69.5
70.9
u/l
0.33
255
2318
74
890
0.80
1.00
1.6
1.7
1.3
1.4
mmol/l
0.28
62
782
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
27
372
0.71
0.96
1.1
1.2
—
—
—
0
0
32
236
1.38
0.93
5.9
4.2
0.4
1.0
%
—
5
43
10
55
1.84
0.93
1.0
1.1
—
—
—
0
0
17
110
1.57
0.92
1.1
1.1
—
—
—
0
0
12
71
1.71
0.89
2.5
4.2
53.4
57.4
%
0.60
12
71
12
71
1.71
0.89
2.5
3.6
3.3
4.2
e9/l
1.27
12
71
71
842
0.81
0.85
3.4
3.1
8.1
7.6
mmol/l
0.44
60
716
30
223
1.37
0.84
6.1
4.3
0.0
0.2
%
—
5
36
6
32
1.89
0.82
1.0
1.3
—
—
—
0
0
343
3292
1.19
0.79
12.1
11.0
13.3
13.5
%
1.58
335
3231
15
98
1.55
0.79
3.9
2.6
7.7
9.2
mg/l
0.46
15
90
378
3663
1.23
0.78
10.9
10.1
39.0
39.7
%
1.09
313
3061
21
149
1.43
0.77
4.3
2.2
—
—
—
0
0
30
228
1.34
0.75
6.2
4.3
0.0
0.1
%
—
5
41
309
3225
0.86
0.74
4.2
4.5
14.2
14.2
pmol/l
0.08
285
3058
29
221
1.33
0.72
8.1
6.6
103.7
104.5
mmol/l
0.36
29
214
341
3524
0.85
0.67
3.3
3.5
5.6
5.6
mmol/l
0.18
320
3321
24
180
1.35
0.66
2.0
3.2
1.6
1.8
mmol/l
0.10
17
137
24
180
1.35
0.66
2.0
3.2
5.8
5.8
kpa
0.03
24
175
107
953
1.16
0.66
4.4
3.8
—
—
—
0
0
5
29
1.73
0.64
1.0
1.8
91.9
91.8
%
—
5
29
94
1057
0.86
0.63
1.3
1.3
0.5
2.1
u/ml
2.15
33
303
11
71
1.56
0.62
1.1
1.5
—
—
—
0
0
15
105
1.44
0.61
12.9
10.6
94.1
94.5
%
0.13
15
105
0
20
0.00
0.60
0.0
1.8
—
—
—
0
0
61
708
0.84
0.60
3.8
3.2
29.7
408.6
mg/l
1.37
39
434
131
1192
1.14
0.60
1.6
1.8
94.2
99.0
pmol/l
0.44
68
641
0
21
0.00
0.60
0.0
3.6
—
—
—
0
0
24
184
1.32
0.59
2.0
3.5
—
—
—
0
0
20
264
0.75
0.59
1.7
1.4
—
—
—
0
0
236
2231
1.13
0.58
2.7
2.7
—
—
—
0
0
8
53
1.52
0.58
6.1
1.9
—
—
—
0
0
0
23
0.00
0.58
0.0
2.7
—
9.7
—
0
15
72
628
1.18
0.58
1.4
1.4
473.7
542.0
titre
0.10
19
138
6
35
1.72
0.58
1.0
1.1
—
—
—
0
0
20
262
0.75
0.56
1.7
1.4
—
—
—
0
0
21
272
0.76
0.55
1.7
1.5
—
—
—
0
0
47
551
0.84
0.53
1.6
1.5
—
—
—
0
0
17
225
0.75
0.52
1.5
1.3
206.1
228.8
miu/ml
—
9
117
6
40
1.51
0.52
1.5
2.0
—
—
—
0
0
21
162
1.31
0.51
2.6
2.3
—
—
—
0
0
17
223
0.75
0.49
1.2
1.3
—
—
—
0
0
18
234
0.76
0.49
1.1
1.1
—
—
—
0
0
7
108
0.64
0.49
1.0
1.1
—
—
—
0
0
7
108
0.64
0.49
1.0
1.1
—
—
—
0
0
7
48
1.47
0.47
5.9
2.0
—
—
—
0
0
5
81
0.61
0.46
1.2
1.0
—
—
—
0
0
31
256
1.23
0.46
2.4
2.3
10.5
10.4
g/l
0.04
31
241
281
2709
1.10
0.43
4.0
3.8
10.1
9.4
mm/h
0.37
264
2555
76
842
0.88
0.43
1.5
1.6
—
—
—
0
0
5
32
1.57
0.42
1.2
1.3
—
—
—
0
0
33
390
0.83
0.42
1.3
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
1.0
—
0
15
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
3.2
—
52.3
—
0
10
66
735
0.88
0.40
4.7
3.8
4.5
7.6
mg/mmol
0.77
43
443
59
662
0.87
0.40
1.3
1.4
—
—
—
0
0
8
60
1.34
0.40
1.9
2.2
117.1
162.0
ug/l
—
8
49
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
9.9
—
0
18
71
786
0.88
0.40
2.7
3.1
1.0
1.0
kg/l
—
9
109
9
67
1.35
0.38
1.3
1.1
—
—
—
0
0
167
1581
1.09
0.37
2.3
2.3
—
—
—
0
0
41
359
1.16
0.34
2.8
2.4
27.4
24.3
%
0.65
36
304
14
109
1.29
0.34
13.6
10.2
0.6
0.7
%
0.59
14
109
130
1222
1.09
0.34
1.7
1.9
—
—
—
0
0
205
2135
0.93
0.33
2.9
2.9
73.8
60.5
ug/l
1.16
194
2032
6
46
1.31
0.33
1.7
1.2
—
—
—
0
0
6
90
0.66
0.33
1.2
1.4
—
—
—
0
0
56
620
0.89
0.32
1.8
2.1
—
—
—
0
0
26
220
1.19
0.32
1.3
1.4
—
—
—
0
0
6
47
1.28
0.32
1.0
1.4
—
—
—
0
0
40
352
1.15
0.32
1.5
1.9
—
—
—
0
0
316
3233
0.92
0.31
4.1
4.3
37.5
37.7
mmol/mol
0.20
299
3069
23
194
1.20
0.30
1.1
1.3
—
0.8
—
0
17
40
355
1.14
0.29
1.3
1.3
—
—
—
0
0
19
158
1.21
0.28
10.3
7.9
—
—
—
0
0
12
94
1.28
0.28
1.9
2.2
1.5
1.2
%
0.26
12
94
88
822
1.09
0.27
1.4
1.3
24.8
25.6
iu/ml
0.03
34
285
8
66
1.22
0.27
1.3
1.1
—
—
—
0
0
405
4008
1.14
0.26
10.0
8.9
—
—
—
0
0
50
455
1.11
0.25
1.7
1.6
1217.0
1134.3
nmol/l
0.22
35
359
40
444
0.89
0.25
1.3
1.2
167.2
146.5
iu/ml
—
8
191
16
190
0.84
0.24
1.8
1.6
—
—
—
0
0
362
3670
0.92
0.23
3.2
3.6
1.6
1.6
mmol/l
0.08
340
3501
95
1006
0.93
0.23
1.5
1.7
—
—
—
0
0
91
859
1.07
0.22
1.7
2.0
106.1
113.5
u/l
0.23
84
817
43
392
1.11
0.22
1.4
1.3
—
—
—
0
0
361
3657
0.93
0.21
4.8
5.1
1.7
2.0
mu/l
0.55
332
3492
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
1.2
—
0
10
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
6.0
—
0
12
5
43
1.16
0.21
1.2
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
13
108
1.21
0.20
14.1
10.2
1.8
1.4
%
0.64
13
108
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
9
114
0.79
0.20
6.8
5.9
—
—
—
0
0
84
886
0.94
0.19
1.3
1.3
2.2
2.2
g/l
0.03
60
565
357
3525
1.07
0.19
3.0
3.2
1.2
1.2
mmol/l
0.33
335
3342
6
53
1.13
0.18
1.2
1.4
25.9
29.4
nmol/l
—
6
45
7
59
1.19
0.18
1.0
1.4
—
30.1
—
0
5
82
863
0.94
0.18
1.9
2.0
2.5
2.6
mg/l
0.31
64
744
368
3719
0.93
0.17
3.4
3.8
3.0
2.9
mmol/l
0.60
345
3534
72
759
0.94
0.16
2.0
2.0
292.6
4743.1
umol/l
2.79
62
685
103
988
1.06
0.16
2.4
2.6
22.0
19.5
ng/l
0.12
37
428
69
654
1.07
0.16
1.4
1.4
18.6
22.2
nmol/l
1.46
59
586
27
296
0.91
0.15
1.4
1.2
—
—
—
0
0
9
82
1.10
0.15
1.1
2.8
—
—
—
0
0
11
129
0.85
0.15
1.1
1.1
—
—
—
0
0
7
86
0.81
0.14
1.0
1.2
—
—
—
0
0
45
480
0.93
0.14
1.9
2.9
34.4
327.2
ng/l
0.94
19
252
40
373
1.08
0.14
1.4
1.5
—
—
—
0
0
8
99
0.80
0.13
1.3
1.2
—
111.7
—
0
12
25
228
1.10
0.13
1.6
1.7
—
—
—
0
0
43
458
0.93
0.13
1.3
1.1
—
—
—
0
0
365
3682
0.95
0.13
3.3
3.6
4.9
4.9
mmol/l
0.57
346
3524
33
355
0.92
0.13
2.3
1.8
30.0
29.5
s
0.26
33
349
24
219
1.10
0.13
1.6
1.7
—
—
—
0
0
25
229
1.10
0.12
1.6
1.7
—
—
—
0
0
80
832
0.95
0.12
6.4
4.8
—
—
—
0
0
83
862
0.95
0.12
1.7
1.7
0.7
0.7
mg/l
0.01
62
630
25
230
1.09
0.11
1.6
1.7
—
—
—
0
0
38
357
1.07
0.11
1.6
2.1
3.7
4.4
umol/l
1.29
26
300
102
988
1.04
0.11
2.3
2.2
48.8
55.2
u/l
2.09
96
914
99
960
1.04
0.10
2.7
2.3
—
—
—
0
0
13
115
1.13
0.10
1.5
2.0
—
—
—
0
0
27
252
1.08
0.09
1.3
1.2
—
—
—
0
0
5
47
1.06
0.09
1.2
1.2
—
—
nmol/l
—
0
0
11
124
0.88
0.09
1.0
1.2
—
—
—
0
0
59
612
0.96
0.08
1.6
1.6
440.1
37523197.5
pmol/l
1.05
47
549
24
224
1.08
0.08
1.6
1.7
—
—
—
0
0
17
185
0.92
0.08
1.5
1.7
—
—
—
0
0
7
64
1.10
0.08
9.4
6.4
323.9
384.5
umol/l
—
7
54
7
64
1.10
0.08
4.7
4.8
—
—
—
0
0
7
82
0.85
0.07
1.4
1.2
—
—
—
0
0
32
334
0.95
0.05
1.5
1.4
—
—
—
0
0
16
171
0.93
0.05
2.4
1.6
—
—
—
0
0
31
298
1.04
0.04
4.2
5.1
1.0
1.0
mmol/l
0.84
31
278
62
608
1.02
0.03
1.2
1.3
—
—
—
0
0
11
118
0.93
0.03
1.1
1.1
0.3
2.4
u/ml
—
5
47
84
830
1.01
0.02
1.2
1.3
9.1
11.8
u/ml
0.13
36
355
13
123
1.06
0.01
1.0
1.2
—
2.8
—
0
18
38
372
1.02
0.01
2.0
2.1
1432.3
4302.9
u/l
0.95
15
153
23
223
1.03
0.01
6.7
12.3
1.5
1.2
inr
—
7
37
14
146
0.96
0.00
2.4
2.1
—
—
—
0
0
21
216
0.97
0.00
1.0
1.1
—
—
—
0
0
13
125
1.04
0.00
1.1
1.1
2.2
2.6
ug/l
0.43
13
115
24
236
1.02
0.00
3.2
2.2
—
—
—
0
0
22
223
0.99
0.00
2.9
3.0
—
—
—
0
0
10
102
0.98
0.00
1.0
1.1
0.0
1.3
u/ml
—
5
42
40
402
0.99
0.00
1.3
1.3
—
—
—
0
0
15
151
0.99
0.00
1.2
1.2
—
—
—
0
0
19
191
0.99
0.00
10.3
6.1
1.2
1.2
mmol/l
0.05
19
182
58
581
1.00
0.00
2.4
2.4
124.6
83.5
ug/g
0.74
42
451
5
54
0.93
0.00
3.0
1.8
583.6
11481.1
e6/l
—
5
43
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
60
1.00
0.00
1.7
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
7.8
—
0
5
7
74
0.95
0.00
3.3
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
62
0.97
0.00
1.3
1.0
—
—
—
0
0
8
87
0.92
0.00
3.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
0.00
1.4
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
8
79
1.01
0.00
1.3
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
1.5
—
0
7
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
57
0.88
0.00
1.4
2.0
0.1
1.3
ug/l
—
5
52
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
80
800
1.00
0.00
2.8
2.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
11.0
—
26.5
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
357.3
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_CERVIX_UTERI_ENDOCERVIX_EXALLC – Carcinoma in situ of cervix uteri, endocervix

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).