No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
189 |
4. Check minimum number of eventsNone |
189 |
5. Include endpointsNone |
189 |
6. Filter based on genotype QC (FinnGen only) |
189 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H91
- Name in latin
- Surdomutitas non alibi classificata
Similar endpoints
↥List of similar endpoints to Deaf mutism, not elsewhere classified based on the number of shared cases.
Similar with more cases:
- Other hearing loss
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2290 | 1093 | 1167 |
Only index persons | 1776 | 903 | 873 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | 0.03 | 0.03 |
Only index persons | 0.03 | 0.03 | 0.03 |
Median age at first event (years) | |||
Whole population | 43.90 | 44.20 | 43.06 |
Only index persons | 35.92 | 40.27 | 31.41 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 189 | 101 | 88 |
Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.04 |
Median age at first event (years) | 46.97 | 42.74 | 51.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 180
- Matched controls
- 1799
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint H8_HL_DEAFMUT and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_HL_DEAFMUT | 0.972 [0.76, 1.25] | 0.828 |
Birth year | 0.994 [0.99, 1.0] | 0.144 |
During the follow-up period (1.1.1998 — 31.12.2019), 84 out of 364 females with H8_HL_DEAFMUT died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_HL_DEAFMUT | 1.274 [0.94, 1.72] | 0.117 |
Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 94 out of 329 males with H8_HL_DEAFMUT died.
Mortality risk
Mortality risk for people of age
years, who have H8_HL_DEAFMUT.N-year risk | Females | Males |
---|---|---|
1 | 0.062% | 0.198% |
5 | 0.475% | 1.537% |
10 | 1.164% | 3.742% |
15 | 2.581% | 6.891% |
20 | 4.467% | 12.099% |
Relationships between endpoints
↥Index endpoint: H8_HL_DEAFMUT – Deaf mutism, not elsewhere classified
GWS hits: 2