adrenal gland disease: A disease involving the adrenal gland.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
186 |
4. Check minimum number of eventsNone |
186 |
5. Include endpointsNone |
186 |
6. Filter based on genotype QC (FinnGen only) |
179 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Disorders of adrenal gland, other and/or unspecified
based on the number of shared cases.
Similar with more cases:
- Other disorders of adrenal gland
- Exclusions for E4_PCOS_BROAD
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1308 | 813 | 486 |
| Only index persons | 1013 | 644 | 369 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 49.81 | 46.38 | 55.27 |
| Only index persons | 49.26 | 46.43 | 54.20 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 179 | 111 | 68 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | 50.82 | 44.37 | 61.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 186
- Matched controls
- 1860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB09
ATC
hydrocortisone; systemic
101.7
151.3
81
14
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
+∞
105.5
91
*
E27.8
ICD-10 Finland
Other specified disorders of adrenal gland
+∞
57.3
52
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
24.4
51.6
39
20
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
27.8
26
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
25.6
24
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
273.8
24.2
24
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
23.4
22
*
H02AA02
ATC
fludrocortisone; oral
71.7
22.5
25
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.7
16.0
44
116
25599
ICD-8 Finland
Diseases of adrenal glands, Other and unspecified
+∞
15.9
15
*
E23.03
ICD-10 Finland
Lack of ACTH
+∞
13.7
13
*
M05BA04
ATC
alendronic acid; oral
5.2
13.6
31
69
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
12.6
12
*
2559X
ICD-9 Finland
Disorders of adrenal glands, Unspecified disorder of adrenal glands
+∞
12.6
12
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
12.6
12
*
N06AX21
ATC
duloxetine; oral
3.9
11.9
41
126
25598
ICD-8 Finland
Diseases of adrenal glands, Alii definiti
+∞
11.6
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
11.5
41
129
SPAT1301
SPAT
No procedures
2.9
11.2
77
361
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
10.8
60
249
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
+∞
10.5
10
*
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
20.2
10.4
15
8
H02AB06
ATC
prednisolone; systemic
2.7
10.2
112
661
C03CA01
ATC
furosemide; systemic
2.8
9.6
70
334
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
9.5
9
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.5
9.3
24
59
M05BX04
ATC
denosumab; parenteral
5.1
9.1
20
43
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
9.0
70
343
C03DA01
ATC
spironolactone; oral
3.5
8.9
35
117
H03AA01
ATC
levothyroxine sodium; systemic
2.7
8.7
59
269
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
8.7
84
457
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
21.2
8.6
12
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
8.6
98
575
R60.9
ICD-10 Finland
Oedema, unspecified
5.3
8.6
18
37
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
94.1
8.5
9
*
AA1AD
NOMESCO Finland
CT of head and brain
2.6
8.0
62
301
JN3AD
NOMESCO Finland
Abdominal CT examination
3.3
7.7
31
105
R11
ICD-10 Finland
Nausea and vomiting
3.5
7.5
28
90
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.5
7.3
27
86
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.7
7.3
24
71
K59.09
ICD-10 Finland
Constipation, unspecified
4.2
7.2
20
52
R53
ICD-10 Finland
Malaise and fatigue
2.5
7.2
62
315
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.8
7.0
22
63
A02BC05
ATC
esomeprazole; systemic
2.3
6.9
86
510
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
6.9
28
95
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
6.9
74
413
N03AX16
ATC
[U] pregabalin
2.5
6.9
55
269
R06.0
ICD-10 Finland
Dyspnoea
2.4
6.9
66
351
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.1
6.8
31
113
103
Kela drug reimbursment
Diabetes, insulin-treated
2.5
6.8
55
271
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
6.6
42
183
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.6
6.6
46
211
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
6.5
86
520
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.8
6.5
21
61
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.2
6.4
27
94
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.2
6.4
27
94
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.8
6.3
34
136
2558X
ICD-9 Finland
Disorders of adrenal glands, Other specified disorders of adrenal glands
+∞
6.3
6
*
E27.0
ICD-10 Finland
Other adrenocortical overactivity
+∞
6.3
6
*
SPAT1254
SPAT
Administration of medicine
2.7
6.0
36
152
SPAT1262
SPAT
Handing over of treatment supplies
2.7
6.0
36
152
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.7
6.0
16
30
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
96
125
14.81
77.17
5.6
1.6
281.64
378.97
nmol/l
1.47
86
112
47
113
5.23
19.26
4.3
2.9
1.22
1.23
mmol/l
0.64
42
93
128
703
3.63
15.39
11.1
5.7
1.22
1.21
mmol/l
0.54
99
601
120
649
3.39
14.46
17.1
14.1
1.17
1.27
inr
0.66
50
189
90
442
3.01
12.26
4.9
2.2
58.06
53.32
u/l
0.48
85
411
114
638
3.03
12.22
11.2
5.3
1.22
1.21
mmol/l
0.78
105
580
32
88
4.18
10.80
10.4
8.1
24.92
25.21
mmol/l
0.13
32
88
23
30
8.59
10.77
1.6
1.2
8.94
9.31
u/l
0.03
16
22
21
26
8.96
10.15
3.1
2.2
5.07
5.00
kpa
0.13
21
26
17
15
12.34
9.78
1.3
1.1
—
—
—
0
0
29
82
4.01
9.39
4.1
2.1
9.49
12.39
nmol/l
0.84
24
76
31
92
3.84
9.39
5.4
3.3
4.84
4.46
pmol/l
1.08
25
80
78
398
2.65
9.33
3.6
3.2
1043.73
1010.68
ng/l
0.04
69
337
39
137
3.34
9.17
4.2
2.9
—
—
—
0
0
103
607
2.56
9.06
4.0
2.1
77.11
75.98
nmol/l
0.17
93
538
30
90
3.78
8.93
4.7
2.7
82.33
72.69
ng/l
0.19
24
84
18
22
8.93
8.81
1.4
2.4
14.52
16.52
%
—
6
10
96
559
2.48
8.51
5.5
3.7
30.70
36.70
ng/l
0.23
79
369
91
520
2.47
8.37
4.0
3.3
—
—
—
0
0
49
214
2.75
7.80
2.0
2.0
28.54
29.44
s
0.69
41
208
48
211
2.72
7.52
4.4
3.2
0.82
0.82
mmol/l
0.00
48
201
34
124
3.13
7.45
4.6
4.5
2.36
2.14
mmol/l
0.16
28
99
14
15
9.99
7.42
1.2
1.7
91.20
90.83
%
0.10
14
15
44
186
2.79
7.42
3.4
2.0
23.51
22.27
%
0.17
35
159
66
341
2.45
7.40
1.9
1.8
0.71
0.93
mg/l
0.78
47
269
83
478
2.33
7.25
3.4
3.0
2.33
2.35
mmol/l
0.66
78
428
116
775
2.32
7.06
9.4
5.6
10.90
11.68
umol/l
0.16
107
734
76
426
2.33
7.03
2.5
2.0
138.31
144.78
u/l
0.08
70
407
90
544
2.27
6.93
2.2
1.9
92.90
96.15
pmol/l
0.29
54
276
151
1143
2.71
6.80
12.5
6.8
77.26
77.29
u/l
0.00
140
1064
104
677
2.22
6.57
4.4
2.4
140.91
102.99
ug/l
0.91
97
621
57
289
2.40
6.56
2.3
1.6
492.43
20408610.58
pmol/l
0.50
49
245
29
105
3.09
6.41
1.1
1.2
84.38
115.77
iu/ml
—
8
42
39
171
2.62
6.06
5.1
7.4
102.85
103.80
mmol/l
0.46
39
171
150
1159
2.52
5.99
7.8
3.9
14.74
14.58
pmol/l
0.35
145
1048
49
242
2.39
5.92
2.4
1.7
1274.25
1169.87
nmol/l
0.30
39
181
45
215
2.44
5.84
2.3
1.9
—
—
—
0
0
146
1121
2.41
5.80
6.8
3.8
10.48
10.90
mm/h
0.20
135
1026
122
875
2.15
5.69
8.8
8.8
4.66
4.10
e9/l
1.80
115
756
16
42
4.07
5.67
7.3
7.2
8.36
8.31
kpa
0.04
16
42
60
330
2.21
5.60
3.1
2.0
3.02
3.05
mg/l
0.03
55
283
22
74
3.24
5.47
1.6
1.3
23.14
26.19
iu/l
0.13
17
64
70
415
2.10
5.36
4.1
3.1
0.29
0.37
e6/l
0.20
57
307
14
26
5.73
5.34
4.1
3.2
60.93
59.42
%
0.13
14
26
15
41
3.89
5.04
1.4
1.2
—
—
—
0
0
10
13
8.06
4.91
2.4
1.4
5.89
3.56
nmol/l
—
10
13
66
395
2.04
4.85
5.9
4.1
0.00
0.00
estimate
-0.00
36
128
63
374
2.04
4.71
3.8
3.4
9.55
8.06
mg/mmol
0.08
38
235
7
5
14.47
4.61
1.9
1.4
67.14
57.40
nmol/l
—
7
5
17
56
3.24
4.36
6.8
6.6
25.08
24.60
mmol/l
0.28
17
56
12
26
4.86
4.13
3.8
3.2
4.93
4.99
e9/l
0.02
12
26
85
579
1.86
4.13
6.4
3.7
—
—
—
0
0
161
1361
2.36
4.02
7.7
5.1
41.61
39.16
mmol/mol
1.72
153
1277
13
34
4.03
3.77
3.3
2.8
27.02
24.92
mmol/l
0.80
13
34
44
247
2.02
3.76
4.9
3.3
61.87
75.23
ng/l
0.11
32
185
7
9
8.03
3.59
2.0
2.0
—
—
—
0
0
6
6
10.27
3.52
1.0
1.0
—
—
—
0
0
172
1522
2.73
3.44
37.0
14.5
139.20
139.67
mmol/l
1.21
165
1474
40
224
2.00
3.42
2.9
2.9
4.01
2.90
e6/l
0.32
27
107
8
14
5.92
3.38
1.3
1.2
—
—
—
0
0
172
1526
2.69
3.34
36.9
14.5
3.92
3.96
mmol/l
1.02
165
1480
100
748
1.73
3.33
6.0
3.6
0.03
0.00
estimate
0.49
38
141
31
160
2.13
3.29
13.3
6.3
1.66
1.27
mmol/l
0.25
25
125
9
19
4.92
3.28
2.3
1.2
—
—
—
0
0
12
34
3.70
3.26
1.2
1.7
—
—
—
0
0
46
275
1.89
3.25
1.6
1.3
41.81
28.99
iu/ml
0.15
12
90
53
332
1.83
3.24
2.0
1.5
17.66
20.84
nmol/l
0.88
46
274
163
1419
2.20
3.22
5.4
4.2
5.92
5.83
mmol/l
0.37
152
1314
171
1520
2.55
3.18
30.0
13.1
21.87
22.72
mg/l
0.15
152
1188
29
149
2.12
3.11
2.6
1.8
—
—
—
0
0
12
36
3.49
3.08
1.8
1.3
—
—
—
0
0
99
750
1.68
3.06
7.7
4.8
0.00
0.00
estimate
-0.00
36
129
21
96
2.34
2.96
2.8
1.4
—
—
—
0
0
56
367
1.75
2.92
1.5
1.2
1.06
0.90
u/ml
0.13
17
97
89
662
1.66
2.90
3.0
2.4
—
—
—
0
0
28
146
2.08
2.89
2.6
1.7
—
—
—
0
0
16
65
2.60
2.88
2.7
5.2
0.58
0.63
%
0.30
16
65
99
762
1.64
2.79
6.1
3.6
0.00
0.00
estimate
-0.00
32
128
16
68
2.48
2.64
2.7
5.1
0.80
1.35
%
1.68
16
68
9
25
3.73
2.61
1.1
2.0
—
—
—
0
0
9
25
3.73
2.61
1.1
2.0
—
—
—
0
0
17
76
2.36
2.53
2.5
1.7
—
—
—
0
0
156
1375
1.83
2.42
8.6
4.6
1.70
1.87
mu/l
1.01
147
1269
8
22
3.75
2.39
3.3
3.0
105.38
106.09
mmol/l
—
8
22
11
39
2.93
2.39
3.3
2.7
—
—
—
0
0
19
92
2.19
2.37
2.1
1.3
—
—
—
0
0
7
18
4.00
2.27
1.0
1.1
—
—
—
0
0
9
29
3.21
2.26
1.1
1.4
—
—
—
0
0
10
35
2.96
2.24
1.2
1.7
—
—
—
0
0
5
9
5.67
2.22
1.4
1.1
—
—
—
0
0
5
9
5.67
2.22
1.2
1.7
—
—
—
0
0
5
9
5.67
2.22
1.2
1.7
—
—
—
0
0
8
24
3.43
2.20
1.3
1.7
—
—
—
0
0
6
14
4.39
2.17
4.3
6.1
14.12
14.14
mg/l
—
6
14
7
20
3.59
2.07
1.1
1.8
—
—
—
0
0
12
50
2.50
2.07
2.2
2.0
—
—
—
0
0
158
1417
1.76
2.05
28.4
11.9
80.39
82.82
ml/min/173m2
0.64
144
1162
7
22
3.26
1.90
1.1
1.4
—
—
—
0
0
55
400
1.53
1.82
1.5
1.6
1.44
1.33
mmol/l
0.55
43
331
12
54
2.31
1.78
2.0
1.9
0.86
5.76
ug/l
0.48
12
49
6
18
3.41
1.76
1.2
1.9
—
—
—
0
0
6
18
3.41
1.76
1.2
1.9
—
—
—
0
0
5
14
3.64
1.62
1.6
1.2
—
—
—
0
0
36
244
1.59
1.61
2.9
2.8
0.78
1.00
e6/l
0.26
24
126
7
26
2.76
1.59
1.1
1.8
—
—
—
0
0
12
57
2.18
1.59
2.2
2.1
—
—
—
0
0
8
33
2.49
1.55
1.3
1.2
—
—
—
0
0
0
45
0.00
1.52
0.0
1.6
—
—
—
0
0
9
40
2.31
1.42
1.3
1.4
—
—
—
0
0
5
17
2.99
1.36
1.0
1.0
—
—
—
0
0
6
24
2.55
1.31
1.7
1.3
—
—
—
0
0
39
282
1.48
1.31
1.6
1.2
0.92
7.95
u/ml
—
10
110
27
182
1.57
1.25
1.9
2.1
—
—
—
0
0
5
19
2.67
1.22
1.4
1.2
—
—
—
0
0
43
324
1.43
1.17
6.3
3.8
1.02
1.02
kg/l
—
10
44
152
1404
1.45
1.15
4.4
3.8
1.45
1.25
mmol/l
2.52
135
1300
10
51
2.02
1.13
1.2
2.3
—
—
—
0
0
10
51
2.02
1.13
1.2
2.3
6.33
7.88
g/l
—
10
46
10
51
2.02
1.13
1.2
2.3
2.97
3.69
g/l
—
10
46
7
31
2.31
1.11
6.0
1.3
—
—
—
0
0
5
21
2.42
1.09
1.0
1.1
—
—
—
0
0
157
1466
1.46
1.05
4.9
4.2
4.65
4.71
mmol/l
0.27
145
1371
116
1039
1.31
0.99
6.1
2.7
50.65
42.72
u/l
0.81
104
980
5
23
2.21
0.98
1.4
1.6
—
—
—
0
0
10
54
1.90
0.98
2.1
1.8
—
—
—
0
0
22
150
1.53
0.98
4.7
2.3
29.29
29.79
u/l
0.03
17
125
155
1453
1.40
0.92
4.9
4.2
1.45
1.50
mmol/l
0.86
140
1350
158
1487
1.42
0.91
5.3
4.7
2.72
2.79
mmol/l
0.45
144
1379
6
30
2.03
0.87
2.5
1.4
—
—
—
0
0
6
30
2.03
0.87
2.5
1.4
—
—
—
0
0
167
1593
1.47
0.83
35.0
14.7
79.57
74.51
umol/l
0.85
167
1593
36
280
1.35
0.83
2.5
2.9
2.49
2.44
mmol/l
1.21
30
250
27
200
1.41
0.82
2.1
2.2
—
—
—
0
0
8
48
1.70
0.80
1.3
1.2
—
—
—
0
0
8
48
1.70
0.80
1.3
1.2
—
—
—
0
0
25
331
0.72
0.79
3.4
4.4
24.94
20.07
%
0.83
14
154
5
24
2.11
0.75
1.4
1.5
—
—
—
0
0
5
24
2.11
0.75
1.4
1.5
—
—
—
0
0
9
56
1.64
0.73
1.8
1.4
—
—
—
0
0
5
25
2.03
0.73
1.0
1.4
—
—
—
0
0
16
111
1.48
0.68
2.3
2.3
—
18.99
—
0
7
40
326
1.29
0.67
3.4
2.2
—
—
—
0
0
167
1605
1.40
0.65
17.3
9.4
25.51
25.17
u/l
0.12
161
1549
8
49
1.66
0.63
1.1
2.4
2.77
3.09
g/l
—
8
44
8
49
1.66
0.63
1.6
2.2
—
—
—
0
0
173
1680
1.43
0.54
42.5
19.0
38.90
40.29
%
1.23
161
1593
14
100
1.43
0.53
1.2
1.2
—
40.86
—
0
5
173
1681
1.42
0.53
41.4
19.0
4.47
4.48
e12/l
0.13
168
1635
21
166
1.30
0.46
3.8
4.2
31.75
31.43
%
0.04
16
108
15
113
1.36
0.44
2.0
2.3
11.03
4.96
ug/l
0.51
15
101
106
990
1.16
0.44
3.8
3.2
—
—
—
0
0
5
34
1.48
0.40
1.6
1.6
—
—
—
0
0
5
35
1.44
0.39
1.2
1.2
—
—
—
0
0
5
36
1.40
0.38
5.2
2.4
43.00
38.12
ug/min
—
5
17
5
78
0.63
0.36
1.8
1.5
—
—
—
0
0
6
45
1.34
0.34
1.2
2.4
0.00
1.27
g/l
—
6
40
35
311
1.15
0.27
2.0
1.5
—
—
—
0
0
5
40
1.26
0.22
1.0
1.3
—
—
—
0
0
5
42
1.20
0.21
1.0
2.4
34.14
38.45
g/l
—
5
37
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
17.27
—
0
12
6
48
1.26
0.20
1.7
1.3
—
—
—
0
0
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
21
236
0.88
0.18
2.7
2.9
2.33
0.68
ug/l
0.54
15
150
43
404
1.08
0.14
5.4
4.8
3.30
2.79
ug/l
0.12
36
362
9
106
0.84
0.13
1.9
2.0
—
—
—
0
0
9
83
1.09
0.07
1.1
1.0
—
—
—
0
0
29
278
1.05
0.05
1.4
1.4
—
—
—
0
0
16
166
0.96
0.00
8.9
6.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
8
89
0.89
-0.00
1.3
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
105.57
—
0
7
0
5
0.00
-0.00
0.0
2.6
—
237.80
—
0
5
8
84
0.95
-0.00
1.5
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
33.40
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_ADRENAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_ADRENAS | 2.633 [1.78, 3.89] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.58 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 411 females with E4_ADRENAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_ADRENAS | 2.646 [1.65, 4.25] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 264 males with E4_ADRENAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_ADRENAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.191% | 0.525% |
| 5 | 1.462% | 3.045% |
| 10 | 3.893% | 7.638% |
| 15 | 7.674% | 14.4% |
| 20 | 13.363% | 23.783% |
Relationships between endpoints
↥Index endpoint: E4_ADRENAS – Disorders of adrenal gland, other and/or unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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