Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C96
  • Hospital discharge: ICD-9 202
  • Hospital discharge: ICD-8 202
  • Cause of death: ICD-10 C96
  • Cause of death: ICD-9 202
  • Cause of death: ICD-8 202

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
C81-C96
Name in latin
Neoplasmata maligna alia et non specificata textus lymphatici, haematopoetici et cognati

Similar endpoints

List of similar endpoints to Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 314 146 168
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 55.73 53.03 58.08

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
289
Matched controls
2888
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
209.5
161.7
156
16
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
155.7
135
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
718.4
61.1
58
*
L03AA02
ATC
filgrastim; parenteral
642.2
55.5
53
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.6
49.6
115
186
XW000
NOMESCO Finland
Bone marrow biopsy
21.8
48.8
73
44
JN4BD
NOMESCO Finland
Extensive body CT
14.4
47.1
84
80
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
45.0
42
*
20298
ICD-8 Finland
Other neoplasms of lymphoid tissue, Lymphomata alia
+∞
43.9
41
*
H02AB02
ATC
dexamethasone; systemic
48.4
43.3
52
13
A04AA01
ATC
ondansetron; systemic, rectal
26.3
38.8
54
25
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
36.2
34
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
31.9
30
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
322.7
29.3
29
*
WW500
NOMESCO Finland
Blood transfusion
18.0
29.3
46
30
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
309.9
28.3
28
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.4
27.6
56
65
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
27.5
26
*
C96.2
ICD-10 Finland
Malignant mast cell tumour
+∞
25.4
24
*
20199
ICD-8 Finland
Hodgkin's disease
+∞
25.4
24
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
24.3
23
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
23.2
22
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
130.4
22.9
24
*
JN4AD
NOMESCO Finland
Body CT examination
14.4
22.4
38
30
L03AA13
ATC
pegfilgrastim; parenteral
+∞
22.2
21
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
18.2
22.0
34
21
WF002
NOMESCO Finland
Radical radiotherapy
+∞
21.1
20
*
130
Kela drug reimbursment
Malignant tumour
+∞
21.1
20
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
21.1
20
*
N02AA05
ATC
oxycodone; systemic
4.9
20.4
73
185
PJA10
NOMESCO Finland
Exploration of lymph nodes
62.2
20.2
23
*
ZX120
NOMESCO Finland
Intravenous
6.0
20.2
59
118
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
20.0
19
*
C96.7
ICD-10 Finland
Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
+∞
20.0
19
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
+∞
20.0
19
*
Q82.2
ICD-10 Finland
Mastocytosis
214.1
19.8
20
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
49.8
19.5
23
5
R50.9
ICD-10 Finland
Fever, unspecified
4.5
19.2
75
207
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
75.1
19.0
21
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
19.0
18
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
17.9
17
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
101.4
17.8
19
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
191.2
17.7
18
*
XX3DW
NOMESCO Finland
Time consuming IT work
8.7
17.0
37
48
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
16.8
16
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
16.5
58
142
M04AA01
ATC
allopurinol; systemic
3.9
16.5
77
248
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
15.8
15
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
15.8
15
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
15.8
15
*
A02BC02
ATC
pantoprazole; systemic
2.9
15.4
212
1405
Z51.5
ICD-10 Finland
Palliative care
11.8
15.4
28
26
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
25.0
15.3
21
9
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
15.3
104
441
1XC02
NOMESCO Finland
NA
33.7
15.0
19
6
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
14.7
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
14.7
14
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
157.6
14.6
15
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
15.5
14.3
23
16
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
+∞
13.6
13
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
13.6
13
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
13.6
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
12.6
149
862
20293
ICD-8 Finland
Other neoplasms of lymphoid tissue, Neoplasma benignum sive NUD medullae osseae
+∞
12.6
12
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
12.6
12
*
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
+∞
12.6
12
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
12.6
12
*
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
+∞
12.6
12
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
12.6
12
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
+∞
12.6
12
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
12.6
12
*
116
Kela drug reimbursment
Prostate cancer
+∞
12.6
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
12.0
61
207
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.3
11.8
20
16
B01AB05
ATC
enoxaparin; parenteral
2.6
11.6
102
495
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
+∞
11.5
11
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
11.5
11
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
11.5
11
*
A04AD12
ATC
aprepitant; systemic
+∞
11.5
11
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
11.5
11
*
H02AB06
ATC
prednisolone; systemic
2.4
11.3
159
984
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.3
10.5
39
100
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
10.5
10
*
2024A
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Leukaemic reticuloendotheliosis
+∞
10.5
10
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
10.5
10
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.9
10.5
29
54
JN6AD
NOMESCO Finland
CT of torso and neck
33.9
10.4
13
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
24.4
10.3
14
6
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
10.3
79
350
WZC30
NOMESCO Finland
Teaching
3.8
9.7
42
124
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
103.3
9.5
10
*
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
22.6
9.4
13
6
HAC20
NOMESCO Finland
Total mastectomy
+∞
9.4
9
*
20228
ICD-8 Finland
Other neoplasms of lymphoid tissue, Other primary malignant neoplasms of lymphoid tissue
+∞
9.4
9
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
9.4
9
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
+∞
9.4
9
*
L01CB01
ATC
etoposide; systemic
+∞
9.4
9
*
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
9.4
9
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
9.1
31
73
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
8.9
64
271
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
8.9
103
564
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
9.4
8.7
17
19
HA1AA
NOMESCO Finland
X-ray mammography
8.3
8.5
18
23
9650/3-C77.0
ICD-O-3
Hodgkin lymphoma, NOS, of lymph nodes of head, face and neck
+∞
8.4
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.4
8
*
9741/3-C42.1
ICD-O-3
Malignant mastocytosis of bone marrow
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
8.4
8
*
ZX112
NOMESCO Finland
Subcutaneous
17.8
8.1
12
7
L02BG04
ATC
letrozole; oral
22.8
8.1
11
5
R4110
NOMESCO Finland
Physiotherapy
2.3
8.0
85
439
WX892
NOMESCO Finland
Monitored bed care
3.6
8.0
36
111
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.8
80
406
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.4
7.7
22
43
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
25.8
7.6
10
*
B01AB10
ATC
tinzaparin; parenteral
4.5
7.4
25
59
R4190
NOMESCO Finland
Nutritional therapy
7.2
7.4
17
25
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
7.3
34
107
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
7.3
7
*
L01AA02
ATC
chlorambucil; oral
+∞
7.3
7
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
7.3
7
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
+∞
7.3
7
*
9591/3-C77.0
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of head, face and neck
+∞
7.3
7
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
7.3
7
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
7.3
7
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
7.3
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
7.3
7
*
L03AA04
ATC
NA
+∞
7.3
7
*
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
7.3
7
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
7.3
7
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.5
7.3
33
102
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
30.8
7.2
9
*
WX402
NOMESCO Finland
General anaesthesia
2.8
6.9
46
184
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
6.8
144
983
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
41.0
6.8
8
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
41.0
6.8
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.8
93
537
J05AB01
ATC
aciclovir; systemic
2.4
6.7
63
306
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.4
6.7
23
56
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
6.6
34
116
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
12.6
6.6
11
9
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.6
6.6
18
34
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
6.5
66
333
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
71.4
6.5
7
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
7.3
6.3
14
20
2029X
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue
+∞
6.3
6
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
6.3
6
*
C81.2
ICD-10 Finland
Mixed cellularity classical Hodgkin lymphoma
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
2015X
ICD-9 Finland
Hodgkin's disease, Nodular sclerosis[MORBUS HODGKIN, NODULAR SCLEROSIS, NUD]
+∞
6.3
6
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
6.3
6
*
2008X
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Other named variants
+∞
6.3
6
*
9680/3-C77.8
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph nodes of multiple regions
+∞
6.3
6
*
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
+∞
6.3
6
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
6.3
6
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
6.3
6
*
C96.1
ICD-10 Finland
Malignant histiocytosis
+∞
6.3
6
*
2000B
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Reticulosarcoma[LYMPHOMA MALIGNUM DIFFUSUM]
+∞
6.3
6
*
L01AA03
ATC
melphalan; systemic
+∞
6.3
6
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
6.3
6
*
L02BB03
ATC
bicalutamide; oral
+∞
6.3
6
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
27.3
6.3
8
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
6.2
62
310
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.9
6.1
12
14
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.8
6.1
19
42

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
102
64
23.12
125.63
1.8
1.2
—
—
—
0
0
64
18
44.40
104.53
1.5
1.1
—
—
—
0
0
106
127
12.09
87.37
1.3
1.4
—
—
—
0
0
126
221
8.85
75.67
1.4
1.5
—
—
—
0
0
58
36
19.53
70.21
1.6
2.1
—
—
—
0
0
123
254
7.32
62.22
1.5
1.4
—
—
—
0
0
60
6
123.13
57.12
1.4
1.0
—
—
—
0
0
206
750
6.08
54.74
10.4
5.2
—
—
—
0
0
129
325
6.04
51.98
1.6
1.8
—
—
—
0
0
237
1071
5.95
45.96
11.1
5.3
2.8
3.0
%
0.59
229
996
232
1035
5.75
45.57
11.1
5.4
0.7
0.7
%
0.00
225
960
237
1076
5.90
45.55
11.3
5.6
9.6
8.7
%
2.34
230
1005
238
1101
5.80
44.20
11.1
5.5
27.3
27.6
%
0.09
231
1018
81
151
6.88
44.10
4.6
1.8
9.9
10.9
g/l
0.70
76
141
234
1094
5.47
42.12
10.4
5.3
55.5
57.4
%
1.23
226
1019
241
1155
5.67
42.00
10.2
5.1
0.6
0.6
e9/l
0.96
216
990
55
71
9.18
41.34
4.6
1.5
47.3
29.1
mg/l
1.07
46
61
241
1164
5.60
41.32
10.2
5.1
0.0
0.0
e9/l
0.15
216
1002
245
1205
5.70
40.89
10.9
5.3
0.2
0.2
e9/l
1.12
225
1056
38
29
14.77
40.68
1.5
1.2
—
—
—
0
0
255
1300
6.12
40.57
22.1
6.1
4.1
4.3
e9/l
0.23
239
1135
242
1184
5.55
40.50
10.3
5.2
2.0
1.8
e9/l
0.30
227
1034
54
70
9.11
40.42
4.6
1.5
55.0
45.7
mg/l
0.41
45
60
239
1182
5.28
38.76
12.9
3.8
10.6
12.2
umol/l
1.63
234
1109
219
1017
4.81
38.51
9.2
3.8
33.6
35.7
g/l
5.96
213
937
78
159
6.20
38.49
3.3
1.4
—
—
—
0
0
107
294
5.00
37.58
3.5
2.2
1.7
1.8
%
0.54
101
265
115
336
4.82
37.41
5.9
2.7
0.8
0.8
mmol/l
0.91
109
309
27
13
22.63
35.94
2.6
1.3
1.4
1.2
e9/l
—
21
8
165
658
4.18
34.91
5.7
2.4
335.9
9999.2
umol/l
3.78
158
567
132
460
4.23
33.51
6.4
2.2
2.5
2.4
mmol/l
6.56
125
388
141
523
4.08
32.64
18.4
4.4
—
—
—
0
0
23
10
24.74
31.74
2.0
1.4
16.8
8.0
%
—
10
5
165
693
3.91
31.66
8.4
2.9
7.4
7.4
ph
0.31
37
108
31
27
12.63
30.49
1.5
1.1
237.0
269.6
u/ml
0.17
20
16
82
215
4.81
29.91
4.3
2.3
67.8
67.6
e9/l
0.01
61
168
99
307
4.25
28.98
2.4
2.4
21.3
24.1
%
1.06
90
262
39
51
8.59
28.71
1.6
1.2
—
—
—
0
0
153
646
3.67
28.44
7.9
4.0
—
—
—
0
0
102
328
4.12
28.33
2.3
2.3
2.2
2.3
g/l
1.50
96
302
38
49
8.69
28.28
5.2
1.4
—
—
—
0
0
58
118
5.80
28.24
2.6
1.5
45.7
5.3
ug/l
0.83
45
92
170
772
3.62
28.12
7.8
2.0
2.4
2.4
mmol/l
0.08
156
631
208
1080
3.74
27.74
10.9
5.3
1.2
1.2
mmol/l
0.15
203
963
219
1198
3.74
26.42
11.8
5.7
1.2
1.2
mmol/l
0.53
185
1031
105
367
3.80
25.59
2.4
2.3
11.8
13.7
umol/l
1.63
100
335
36
49
8.17
25.57
2.2
1.9
488.5
16.1
u/ml
1.02
25
37
66
164
4.83
25.46
8.2
4.8
1.0
0.7
%
0.71
41
41
32
42
8.37
23.37
2.0
1.3
—
—
—
0
0
61
155
4.64
22.77
8.6
4.9
0.4
0.1
%
0.95
37
35
60
151
4.68
22.66
8.2
4.9
0.7
0.2
%
1.45
32
30
191
1027
3.19
22.30
17.8
8.0
0.0
0.0
e9/l
0.63
166
818
20
14
15.19
22.11
3.1
1.3
3304.2
1001.2
u/ml
1.18
20
14
152
722
3.14
21.98
2.7
1.6
—
—
—
0
0
48
103
5.32
21.85
2.0
1.8
1.4
1.5
g/l
0.25
39
90
78
261
3.65
19.80
4.6
2.4
8.3
7.1
umol/l
0.26
72
226
133
636
2.89
18.27
3.7
2.8
—
—
—
0
0
135
659
2.84
17.73
3.9
2.8
0.4
0.5
e6/l
0.30
110
486
136
671
2.81
17.45
4.4
2.2
—
—
—
0
0
53
149
4.08
17.14
7.8
5.0
0.0
0.0
%
0.01
32
31
141
718
2.75
16.89
3.9
2.9
45.6
156.5
e6/l
0.62
117
549
16
0
+∞
16.82
5.1
0.0
0.3
—
umol/l
—
16
0
178
1030
2.68
16.35
5.6
3.9
—
—
—
0
0
260
1834
3.43
16.26
18.7
5.2
91.6
75.4
u/l
4.51
254
1672
33
67
5.39
15.85
2.9
2.1
21.8
20.7
s
0.63
33
60
173
1000
2.63
15.73
3.8
2.7
373.8
131.5
ug/l
2.98
165
919
20
24
8.83
15.55
1.3
1.2
—
—
—
0
0
125
625
2.66
15.21
2.1
2.1
3.1
3.0
mg/l
0.06
108
532
18
20
9.49
14.80
1.4
1.3
—
—
—
0
0
18
20
9.49
14.80
1.4
1.3
—
—
—
0
0
18
20
9.49
14.80
1.4
1.3
—
—
—
0
0
18
20
9.49
14.80
1.4
1.3
—
—
—
0
0
59
203
3.35
14.05
7.6
6.2
11.6
10.9
mmol/l
0.24
54
192
167
1000
2.43
13.39
12.2
10.4
1.3
1.3
inr
0.08
43
277
105
508
2.60
13.38
2.2
1.6
3.3
1.1
mg/l
0.70
85
390
148
845
2.42
13.14
4.7
3.3
431.8
105.9
e6/l
0.37
118
594
53
181
3.32
12.72
1.4
1.1
—
—
—
0
0
17
7
25.56
12.60
3.2
1.4
0.1
0.2
e9/l
—
17
7
14
14
10.42
12.32
2.8
2.3
—
—
—
0
0
55
196
3.19
12.30
7.8
7.1
—
—
—
0
0
79
345
2.72
12.24
1.8
2.0
—
—
—
0
0
104
521
2.49
12.15
4.4
2.1
—
—
—
0
0
93
443
2.56
12.08
2.6
1.3
2.3
2.6
g/l
0.46
66
260
17
23
7.76
11.96
1.1
1.1
—
—
—
0
0
249
1841
2.70
11.85
6.7
4.0
18.0
12.1
mm/h
4.62
239
1669
96
471
2.50
11.66
3.3
2.4
499.1
560.0
mosm/kgh2o
2.34
88
385
211
1459
2.36
11.44
7.4
4.5
6.6
6.8
mmol/l
0.56
202
1355
13
13
10.39
11.41
1.5
1.2
—
—
—
0
0
100
517
2.37
10.70
3.1
2.2
5.3
4.9
e6/l
0.07
92
447
60
244
2.80
10.55
4.4
3.2
2.0
2.1
mmol/l
0.08
46
197
95
485
2.37
10.43
9.5
4.6
—
—
—
0
0
19
37
5.40
9.48
4.3
3.2
52.4
58.1
%
0.67
19
37
13
6
22.51
9.42
1.2
1.0
—
—
—
0
0
97
519
2.26
9.42
4.5
3.7
280.5
297.7
ng/l
0.03
79
431
66
298
2.54
9.38
8.0
5.8
104.3
104.6
mmol/l
0.22
66
293
17
31
5.74
9.07
1.1
1.0
—
—
—
0
0
123
767
1.99
7.74
2.7
2.3
49.9
57.0
u/l
1.67
108
705
17
36
4.94
7.73
4.2
2.7
3.3
4.5
e9/l
1.53
17
36
13
22
6.12
7.44
3.1
1.1
—
—
—
0
0
99
583
2.02
7.24
1.5
1.4
—
—
—
0
0
157
1088
1.89
7.03
2.1
2.0
87.9
94.0
pmol/l
0.89
94
564
104
642
1.93
6.54
1.4
1.5
18.7
20.4
nmol/l
0.65
91
545
16
38
4.38
6.36
1.1
1.1
—
—
—
0
0
13
26
5.17
6.28
4.6
3.0
—
—
—
0
0
58
294
2.19
6.22
1.6
1.3
1260.0
506.1
titre
0.75
12
75
43
195
2.40
5.96
4.0
3.7
76.5
84.7
ng/l
0.32
38
171
33
132
2.68
5.92
1.3
1.2
451.1
216.3
u/ml
0.59
27
119
11
20
5.66
5.85
1.4
1.2
—
—
—
0
0
55
282
2.15
5.71
1.7
1.7
—
—
—
0
0
87
532
1.88
5.51
1.8
1.7
995.9
1177.6
nmol/l
1.41
70
392
20
64
3.27
5.29
3.3
3.9
—
—
—
0
0
11
23
4.92
5.05
1.2
1.3
—
—
—
0
0
217
1762
1.75
4.92
5.1
4.0
—
—
—
0
0
10
20
5.13
4.81
8.7
4.6
—
—
—
0
0
15
43
3.61
4.67
1.1
1.1
—
—
—
0
0
16
48
3.46
4.67
1.1
1.1
—
—
—
0
0
18
63
2.97
4.13
1.2
1.3
8.8
427.9
e6/l
0.82
13
54
18
63
2.97
4.13
1.2
1.1
12.9
51.0
e6/l
0.37
12
52
18
63
2.97
4.13
1.4
1.2
—
—
—
0
0
8
10
8.17
4.08
1.4
1.8
3.8
3.8
nmol/l
—
8
10
107
749
1.65
4.07
3.6
3.1
—
—
—
0
0
11
28
4.03
4.01
1.1
1.1
—
—
—
0
0
55
321
1.86
3.95
1.5
1.2
—
—
—
0
0
10
24
4.27
3.91
1.4
1.2
—
—
—
0
0
10
24
4.27
3.91
1.5
1.1
—
—
—
0
0
37
190
2.07
3.82
4.7
3.1
—
—
—
0
0
6
5
12.19
3.78
2.8
1.0
—
—
—
0
0
6
5
12.19
3.78
1.0
1.0
—
—
—
0
0
59
357
1.80
3.77
35.3
26.5
1.1
1.3
inr
—
5
49
23
99
2.43
3.60
1.2
1.2
—
—
—
0
0
10
26
3.94
3.55
1.0
1.1
—
—
—
0
0
9
17
5.42
3.53
1.0
1.1
—
—
—
0
0
16
58
2.85
3.47
4.5
4.0
7.4
7.4
ph
0.54
16
48
10
27
3.79
3.38
1.9
1.4
89.1
89.8
%
—
10
27
19
77
2.56
3.36
1.2
1.2
—
—
—
0
0
8
14
5.83
3.36
2.0
1.7
—
—
—
0
0
202
1690
1.55
3.35
5.3
4.1
—
—
—
0
0
24
110
2.28
3.28
1.3
1.3
—
—
—
0
0
18
74
2.52
3.11
1.7
1.7
—
—
—
0
0
13
45
2.97
3.06
1.2
2.3
—
—
—
0
0
5
5
10.13
2.99
1.2
1.4
—
—
—
0
0
5
5
10.13
2.99
1.4
1.0
107.0
66.6
nmol/l
—
5
5
14
53
2.72
2.83
9.6
2.2
2.1
1.6
mg/l
0.51
14
47
89
644
1.53
2.81
5.5
4.0
0.0
0.0
estimate
0.00
38
190
56
821
0.61
2.80
3.2
3.1
—
—
—
0
0
271
2472
1.70
2.70
36.1
12.9
27.4
23.6
mg/l
1.28
250
1917
46
290
1.69
2.55
8.2
7.9
0.9
1.6
mmol/l
0.66
39
226
9
26
3.53
2.50
1.0
1.1
—
—
—
0
0
7
16
4.45
2.49
3.6
1.5
—
—
—
0
0
42
262
1.70
2.42
8.7
8.1
95.6
94.8
%
0.28
42
253
6
12
5.07
2.41
1.0
1.0
—
—
—
0
0
38
233
1.72
2.33
9.5
8.9
118.0
122.6
g/l
0.71
38
227
128
1027
1.42
2.32
4.6
3.8
28.2
43.0
ng/l
1.61
96
747
23
121
1.97
2.27
12.0
12.1
—
—
—
0
0
7
18
3.95
2.26
1.4
1.6
—
—
—
0
0
7
19
3.74
2.16
1.6
1.3
—
—
—
0
0
224
2454
0.70
2.14
4.3
4.7
1.3
1.5
mmol/l
4.79
201
2239
26
146
1.85
2.14
1.3
1.8
—
—
—
0
0
244
2209
1.47
2.13
34.1
14.1
37.2
39.9
%
5.33
179
1497
227
2476
0.70
2.05
4.4
4.7
4.3
4.6
mmol/l
2.83
207
2269
19
97
2.02
2.05
4.2
5.1
—
—
—
0
0
233
2529
0.69
2.03
4.9
5.3
2.5
2.7
mmol/l
1.79
206
2311
9
33
2.78
1.94
3.0
3.2
—
—
—
0
0
6
16
3.80
1.94
1.3
1.0
—
—
—
0
0
8
28
2.90
1.87
1.5
1.6
—
—
—
0
0
141
1182
1.35
1.86
5.0
3.7
0.0
0.0
estimate
0.00
40
196
7
23
3.09
1.81
2.4
2.1
—
—
—
0
0
216
2357
0.73
1.74
5.9
6.2
40.4
40.4
mmol/mol
0.01
190
2167
142
1205
1.33
1.68
5.0
3.7
0.0
0.0
estimate
0.00
40
193
36
239
1.57
1.66
1.4
1.3
—
—
—
0
0
140
1188
1.32
1.65
6.5
4.9
0.0
0.0
estimate
0.00
41
192
67
507
1.41
1.64
1.2
1.3
0.5
1.9
u/ml
2.16
14
140
27
170
1.64
1.55
6.3
7.3
—
—
—
0
0
8
33
2.46
1.55
2.4
2.4
—
—
—
0
0
41
292
1.46
1.39
1.9
1.5
—
—
—
0
0
206
1871
1.29
1.36
4.3
3.7
15.0
14.9
pmol/l
0.10
187
1673
220
2367
0.76
1.35
4.2
4.2
1.3
1.3
mmol/l
0.85
195
2141
10
48
2.12
1.29
6.8
3.4
—
—
—
0
0
5
18
2.81
1.29
1.8
1.1
—
—
—
0
0
8
36
2.25
1.25
1.5
1.5
—
—
—
0
0
96
801
1.29
1.22
2.1
2.1
154.9
329.4
u/l
0.90
91
749
5
19
2.66
1.22
1.0
1.3
—
—
—
0
0
18
109
1.69
1.21
7.7
8.1
1.5
1.7
%
0.53
18
104
18
109
1.69
1.21
7.7
8.1
0.8
0.9
%
1.07
18
104
79
645
1.30
1.19
4.0
3.3
—
—
—
0
0
10
184
0.53
1.18
1.5
1.4
—
—
—
0
0
274
2611
1.39
1.14
35.6
15.7
139.3
139.8
mmol/l
3.14
268
2530
274
2615
1.38
1.09
36.8
15.8
4.0
4.0
mmol/l
0.58
268
2532
277
2649
1.39
1.07
22.0
8.7
25.9
25.4
u/l
0.22
271
2530
25
171
1.50
1.06
3.0
2.5
3.7
3.6
e9/l
0.08
20
129
30
214
1.44
1.04
1.8
1.4
—
—
—
0
0
11
60
1.86
1.04
3.5
3.0
—
—
—
0
0
5
22
2.29
1.04
2.4
2.9
—
—
—
0
0
12
68
1.80
1.02
1.2
1.1
—
—
—
0
0
24
165
1.49
1.00
9.4
9.3
25.2
24.4
mmol/l
0.54
24
156
7
36
1.97
0.97
1.0
1.1
—
—
—
0
0
6
28
2.16
0.92
1.2
1.3
—
—
—
0
0
24
170
1.45
0.88
1.3
1.5
—
—
—
0
0
34
258
1.36
0.86
2.0
2.6
2.8
7.1
ug/l
3.15
29
220
10
165
0.59
0.84
2.8
2.8
—
—
—
0
0
107
941
1.21
0.83
5.0
3.5
—
—
—
0
0
48
386
1.29
0.82
1.2
1.3
3.7
12.0
u/ml
1.44
14
142
8
47
1.72
0.81
1.5
1.8
55.8
64.1
%
—
8
47
13
82
1.61
0.79
2.9
2.2
0.1
0.3
g/l
—
8
24
6
34
1.78
0.76
1.3
1.3
—
—
—
0
0
5
27
1.87
0.68
1.2
1.2
—
—
—
0
0
20
266
0.74
0.62
1.8
1.6
—
—
—
0
0
23
175
1.34
0.60
2.0
2.4
—
22.9
—
0
5
23
180
1.30
0.51
1.2
1.2
—
—
—
0
0
64
565
1.17
0.48
5.8
3.7
—
—
—
0
0
8
121
0.65
0.46
2.1
1.5
—
—
—
0
0
237
2289
1.14
0.44
5.3
4.5
2.0
2.0
mu/l
0.27
219
2062
75
829
0.87
0.43
3.4
3.2
36.0
270.8
mg/l
1.16
49
542
0
15
0.00
0.41
0.0
1.2
—
4.7
—
0
7
0
15
0.00
0.41
0.0
2.6
—
—
—
0
0
62
554
1.15
0.40
1.7
1.7
469.5
430.9
pmol/l
0.52
50
450
0
18
0.00
0.40
0.0
3.5
—
32.0
—
0
11
48
422
1.16
0.39
1.2
1.3
39.2
32.5
iu/ml
0.10
13
124
80
873
0.89
0.38
3.8
4.0
5.5
7.3
mg/mmol
0.58
53
559
28
237
1.20
0.35
5.6
3.8
—
—
—
0
0
6
46
1.31
0.33
6.0
2.8
—
—
—
0
0
6
46
1.31
0.33
1.5
1.5
—
—
—
0
0
20
166
1.22
0.30
15.2
3.9
5.0
5.1
kpa
0.15
20
153
13
102
1.29
0.30
20.5
4.6
24.5
24.9
mmol/l
0.23
13
97
11
84
1.32
0.30
1.9
1.7
—
—
—
0
0
7
57
1.23
0.29
1.1
1.5
253.6
247.4
mu/l
—
7
50
11
85
1.30
0.28
1.5
2.0
—
—
—
0
0
8
64
1.26
0.27
30.1
3.0
7.8
8.1
kpa
—
8
58
8
66
1.22
0.27
2.1
1.6
2754.9
16047.1
e6/l
—
8
47
16
135
1.20
0.22
2.6
2.5
—
—
—
0
0
12
98
1.23
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
18.0
—
1349.2
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
9.2
—
0.7
—
0
10
11
132
0.83
0.18
4.8
3.5
—
—
—
0
0
13
153
0.84
0.18
1.5
1.2
—
—
—
0
0
71
673
1.07
0.17
1.5
1.7
1.4
1.3
mmol/l
0.15
60
551
29
264
1.11
0.16
2.8
2.3
156.8
120.8
ug/g
0.14
23
201
6
76
0.79
0.16
6.0
4.1
—
—
—
0
0
100
966
1.05
0.13
4.7
3.9
4.1
2.0
ug/l
0.57
93
862
278
2759
1.07
0.10
47.0
18.7
234.9
244.1
e9/l
1.03
268
2675
278
2760
1.06
0.09
47.0
18.8
4.2
4.5
e12/l
16.63
267
2665
278
2762
1.06
0.08
47.1
18.8
7.8
6.7
e9/l
1.19
266
2669
79
769
1.04
0.07
5.2
3.9
—
—
—
0
0
7
80
0.87
0.07
1.6
1.7
—
—
—
0
0
24
226
1.07
0.07
5.6
3.0
—
—
—
0
0
58
562
1.04
0.07
5.4
4.1
1.0
1.0
kg/l
—
5
92
13
120
1.09
0.05
19.7
4.0
—
—
—
0
0
18
171
1.06
0.03
1.4
1.5
—
—
—
0
0
55
539
1.02
0.03
3.1
2.6
0.6
0.8
ug/l
1.59
42
360
261
2601
1.02
0.02
24.2
12.2
—
—
—
0
0
246
2469
0.98
0.02
4.7
4.7
6.0
6.0
mmol/l
0.07
224
2226
86
861
1.00
0.00
3.1
3.1
7.1
7.7
mmol/l
0.60
66
716
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
5
49
1.02
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
0.6
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
8
86
0.93
0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS_EXALLC – Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).