≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

Endpoint Browser PheWeb

CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C96
  • Hospital discharge: ICD-9 — 202
  • Hospital discharge: ICD-8 — 202
  • Cause of death: ICD-10 — C96
  • Cause of death: ICD-9 — 202
  • Cause of death: ICD-8 — 202

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
C81-C96
Name in latin
Neoplasmata maligna alia et non specificata textus lymphatici, haematopoetici et cognati

Similar endpoints

↥

List of similar endpoints to Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 314 146 168
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 55.73 53.03 58.08

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
289
Matched controls
2888
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
209.5
161.7
156
16
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
155.7
135
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
718.4
61.1
58
*
L03AA02
ATC
filgrastim; parenteral
642.2
55.5
53
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.6
49.6
115
186
XW000
NOMESCO Finland
Bone marrow biopsy
21.8
48.8
73
44
JN4BD
NOMESCO Finland
Extensive body CT
14.4
47.1
84
80
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
45.0
42
*
20298
ICD-8 Finland
Other neoplasms of lymphoid tissue, Lymphomata alia
+∞
43.9
41
*
H02AB02
ATC
dexamethasone; systemic
48.4
43.3
52
13
A04AA01
ATC
ondansetron; systemic, rectal
26.3
38.8
54
25
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
36.2
34
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
31.9
30
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
322.7
29.3
29
*
WW500
NOMESCO Finland
Blood transfusion
18.0
29.3
46
30
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
309.9
28.3
28
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.4
27.6
56
65
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
27.5
26
*
20199
ICD-8 Finland
Hodgkin's disease
+∞
25.4
24
*
C96.2
ICD-10 Finland
Malignant mast cell tumour
+∞
25.4
24
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
24.3
23
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
23.2
22
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
130.4
22.9
24
*
JN4AD
NOMESCO Finland
Body CT examination
14.4
22.4
38
30
L03AA13
ATC
pegfilgrastim; parenteral
+∞
22.2
21
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
18.2
22.0
34
21
WF002
NOMESCO Finland
Radical radiotherapy
+∞
21.1
20
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
21.1
20
*
130
Kela drug reimbursment
Malignant tumour
+∞
21.1
20
*
N02AA05
ATC
oxycodone; systemic
4.9
20.4
73
185
PJA10
NOMESCO Finland
Exploration of lymph nodes
62.2
20.2
23
*
ZX120
NOMESCO Finland
Intravenous
6.0
20.2
59
118
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
+∞
20.0
19
*
C96.7
ICD-10 Finland
Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
+∞
20.0
19
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
20.0
19
*
Q82.2
ICD-10 Finland
Mastocytosis
214.1
19.8
20
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
49.8
19.5
23
5
R50.9
ICD-10 Finland
Fever, unspecified
4.5
19.2
75
207
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
75.1
19.0
21
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
19.0
18
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
17.9
17
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
101.4
17.8
19
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
191.2
17.7
18
*
XX3DW
NOMESCO Finland
Time consuming IT work
8.7
17.0
37
48
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
16.8
16
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
16.5
58
142
M04AA01
ATC
allopurinol; systemic
3.9
16.5
77
248
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
15.8
15
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
15.8
15
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
15.8
15
*
A02BC02
ATC
pantoprazole; systemic
2.9
15.4
212
1405
Z51.5
ICD-10 Finland
Palliative care
11.8
15.4
28
26
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
25.0
15.3
21
9
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
15.3
104
441
1XC02
NOMESCO Finland
NA
33.7
15.0
19
6
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
14.7
14
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
14.7
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
157.6
14.6
15
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
15.5
14.3
23
16
C90.0
ICD-10 Finland
Multiple myeloma
+∞
13.6
13
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
+∞
13.6
13
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
13.6
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
12.6
149
862
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
+∞
12.6
12
*
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
+∞
12.6
12
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
12.6
12
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
12.6
12
*
20293
ICD-8 Finland
Other neoplasms of lymphoid tissue, Neoplasma benignum sive NUD medullae osseae
+∞
12.6
12
*
116
Kela drug reimbursment
Prostate cancer
+∞
12.6
12
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
12.6
12
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
12.6
12
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
+∞
12.6
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
12.0
61
207
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.3
11.8
20
16
ZXE00
NOMESCO Finland
One hour or less
2.5
11.6
132
737
B01AB05
ATC
enoxaparin; parenteral
2.6
11.6
102
495
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
11.5
11
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
11.5
11
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
+∞
11.5
11
*
A04AD12
ATC
aprepitant; systemic
+∞
11.5
11
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
11.5
11
*
H02AB06
ATC
prednisolone; systemic
2.4
11.3
159
984
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.3
10.5
39
100
2024A
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Leukaemic reticuloendotheliosis
+∞
10.5
10
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
10.5
10
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
10.5
10
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.9
10.5
29
54
JN6AD
NOMESCO Finland
CT of torso and neck
33.9
10.4
13
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
24.4
10.3
14
6
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
10.3
79
350
WZC30
NOMESCO Finland
Teaching
3.8
9.7
42
124
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
103.3
9.5
10
*
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
22.6
9.4
13
6
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
9.4
9
*
20228
ICD-8 Finland
Other neoplasms of lymphoid tissue, Other primary malignant neoplasms of lymphoid tissue
+∞
9.4
9
*
L01CB01
ATC
etoposide; systemic
+∞
9.4
9
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
9.4
9
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
+∞
9.4
9
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
9.4
9
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
9.1
31
73
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
8.9
64
271
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
8.9
103
564
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
9.4
8.7
17
19
HA1AA
NOMESCO Finland
X-ray mammography
8.3
8.5
18
23
9650/3-C77.0
ICD-O-3
Hodgkin lymphoma, NOS, of lymph nodes of head, face and neck
+∞
8.4
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.4
8
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
9741/3-C42.1
ICD-O-3
Malignant mastocytosis of bone marrow
+∞
8.4
8
*
ZX112
NOMESCO Finland
Subcutaneous
17.8
8.1
12
7
L02BG04
ATC
letrozole; oral
22.8
8.1
11
5
R4110
NOMESCO Finland
Physiotherapy
2.3
8.0
85
439
WX892
NOMESCO Finland
Monitored bed care
3.6
8.0
36
111
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.8
80
406
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.4
7.7
22
43
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
25.8
7.6
10
*
B01AB10
ATC
tinzaparin; parenteral
4.5
7.4
25
59
R4190
NOMESCO Finland
Nutritional therapy
7.2
7.4
17
25
Z2221
NOMESCO Finland
Medical doctor
2.2
7.4
90
497
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
7.3
34
107
L01AA02
ATC
chlorambucil; oral
+∞
7.3
7
*
L03AA04
ATC
NA
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
7.3
7
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
7.3
7
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
7.3
7
*
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
7.3
7
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
+∞
7.3
7
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
7.3
7
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
7.3
7
*
9591/3-C77.0
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of head, face and neck
+∞
7.3
7
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
7.3
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
7.3
7
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.5
7.3
33
102
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
30.8
7.2
9
*
WX402
NOMESCO Finland
General anaesthesia
2.8
6.9
46
184
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
6.8
144
983
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
41.0
6.8
8
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
41.0
6.8
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.8
93
537
J05AB01
ATC
aciclovir; systemic
2.4
6.7
63
306
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.4
6.7
23
56
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
6.6
34
116
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
12.6
6.6
11
9
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.6
6.6
18
34
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
6.5
66
333
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
71.4
6.5
7
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
7.3
6.3
14
20
C81.2
ICD-10 Finland
Mixed cellularity classical Hodgkin lymphoma
+∞
6.3
6
*
L01AA03
ATC
melphalan; systemic
+∞
6.3
6
*
9680/3-C77.8
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph nodes of multiple regions
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
2015X
ICD-9 Finland
Hodgkin's disease, Nodular sclerosis[MORBUS HODGKIN, NODULAR SCLEROSIS, NUD]
+∞
6.3
6
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
6.3
6
*
2029X
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue
+∞
6.3
6
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
6.3
6
*
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
6.3
6
*
C96.1
ICD-10 Finland
Malignant histiocytosis
+∞
6.3
6
*
2000B
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Reticulosarcoma[LYMPHOMA MALIGNUM DIFFUSUM]
+∞
6.3
6
*
L02BB03
ATC
bicalutamide; oral
+∞
6.3
6
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
6.3
6
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
6.3
6
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
6.3
6
*
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
+∞
6.3
6
*
2008X
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Other named variants
+∞
6.3
6
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
27.3
6.3
8
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
6.2
62
310
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.9
6.1
12
14
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.8
6.1
19
42

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS_EXALLC – Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).