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Carcinoma in situ of skin, other sites/unspecified

CD2_INSITU_SKIN_NOS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D04.8&, D04.9&
  • Hospital discharge: ICD-9 232[8-9]
  • Cause of death: ICD-10 D04.8&, D04.9&
  • Cause of death: ICD-9 232[8-9]

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 393 179 214
Unadjusted period prevalence (%) 0.08 0.06 0.09
Median age at first event (years) 76.42 74.70 77.86

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
324
Matched controls
3238
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D04.9
ICD-10 Finland
Carcinoma in situ: Skin, unspecified
4869.8
231.3
195
*
L57.0
ICD-10 Finland
Actinic keratosis
48.1
179.5
240
181
D04.8
ICD-10 Finland
Carcinoma in situ: Skin of other sites
+∞
165.1
144
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
51.3
127.5
154
56
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
442.7
122.2
115
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
26.5
121.1
183
151
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
66.1
101.9
116
27
ZXC50
NOMESCO Finland
Cryotherapy
48.8
93.4
113
35
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
54.3
90.6
107
29
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
539.1
86.4
82
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
85.2
78
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
109.0
83.0
88
11
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
346.3
81.5
79
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
28.6
79.1
110
57
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
836.9
70.9
67
*
TQW99
NOMESCO Finland
Other minor procedure on skin
25.6
67.8
97
53
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
32.8
62.0
82
33
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
190.6
61.3
62
*
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
179.4
58.0
59
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
20.9
55.8
85
54
R23.8
ICD-10 Finland
Other and unspecified skin changes
9.1
54.1
131
225
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
49.2
46
*
S18
ICPC
Laceration/cut
5.6
46.1
221
891
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
177.8
45.1
46
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
41.5
39
*
D06BB10
ATC
imiquimod; topical
15.1
39.7
68
56
ZZR00
NOMESCO Finland
Flap of skin
70.4
38.2
43
7
SPAT1153
SPAT
Removal of sutures
4.8
38.0
181
670
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
27.9
36.6
50
21
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
27.9
36.6
50
21
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
39.9
33.7
42
12
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
+∞
32.9
31
*
C44.52
ICD-10 Finland
Spinocellular carcinoma of the skin on the torso
+∞
31.8
30
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
33.3
31.6
41
14
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
27.3
31.4
43
18
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
331.4
30.3
30
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
29.6
28
*
127
Kela drug reimbursment
Transplant complication
113.8
29.2
31
*
ZZA00
NOMESCO Finland
Split skin graft
16.0
28.6
47
34
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
28.5
27
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
26.4
25
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
11.1
24.8
48
50
L82
ICD-10 Finland
Seborrhoeic keratosis
4.6
24.6
99
284
C44.72
ICD-10 Finland
Spinocellular carcinoma of the skin of the lower extremity including the hip
+∞
24.3
23
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
+∞
24.3
23
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
24.3
23
*
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
+∞
24.3
23
*
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
73.2
24.2
27
*
Z94.0
ICD-10 Finland
Kidney transplant status
134.9
23.9
25
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
+∞
23.2
22
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
+∞
23.2
22
*
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
56.2
22.4
26
5
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
22.1
21
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
22.1
21
*
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
+∞
22.1
21
*
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
22.1
21
*
130
Kela drug reimbursment
Malignant tumour
+∞
21.1
20
*
S77
ICPC
Malignant neoplasm of skin
+∞
21.1
20
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
20.0
19
*
ZXC20
NOMESCO Finland
Use of chemical agents
17.0
19.7
31
20
116
Kela drug reimbursment
Prostate cancer
+∞
18.9
18
*
L04AD01
ATC
ciclosporin; systemic
30.8
17.7
23
8
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
53.0
17.2
20
*
WXQ41
NOMESCO Finland
Photodynamic therapy of head and neck
+∞
16.8
16
*
L04AA06
ATC
mycophenolic acid; systemic
29.3
16.7
22
8
DAB00
NOMESCO Finland
Excision of lesion of auricle
29.3
16.7
22
8
L04AA01
ATC
[U] ciclosporin; systemic
21.5
16.7
24
12
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
178.7
16.6
17
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
178.7
16.6
17
*
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
12.1
16.1
29
26
TQW80
NOMESCO Finland
Local dermatologic skincare
10.0
16.1
32
35
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
+∞
15.7
15
*
8090/3-C44.6
ICD-O-3
Basal cell carcinoma, NOS, of skin of upper limb and shoulder
+∞
15.7
15
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
15.6
182
1058
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.2
15.3
42
76
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
9.4
15.1
31
36
ZQZ00
NOMESCO Finland
Treatment of several skin areas
59.5
14.9
17
*
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
15.1
14.8
24
17
DAB10
NOMESCO Finland
Partial excision of auricle
+∞
14.7
14
*
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
+∞
14.7
14
*
C44.82
ICD-10 Finland
Overall spinocellular carcinoma of the skin
+∞
14.7
14
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
14.7
14
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
156.6
14.6
15
*
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
31.6
14.0
18
6
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.2
13.8
84
323
L57.8
ICD-10 Finland
Other skin changes due to chronic exposure to nonionizing radiation
145.7
13.5
14
*
QCA50
NOMESCO Finland
Cryotherapy of skin of upper limb
145.7
13.5
14
*
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
145.7
13.5
14
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
12.2
13.5
24
21
A98
ICPC
Health maint/preventive medicine
4.4
13.5
304
2511
XQ845
NOMESCO Finland
Dermatoscopy
27.1
13.5
18
7
J01DB01
ATC
cefalexin; oral
2.8
13.4
267
2015
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.3
13.2
29
38
JN4BD
NOMESCO Finland
Extensive body CT
5.1
12.7
41
90
QDA50
NOMESCO Finland
Cryotherapy of skin of lower limb
134.9
12.5
13
*
D07AC01
ATC
betamethasone; topical
2.4
12.2
139
767
B07.9
ICD-10 Finland
Verruca simplex
8.9
12.0
25
30
E0000UV
ATC
NA
2.4
12.0
147
840
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
48.5
12.0
14
*
A12AA04
ATC
calcium carbonate; oral
11.1
11.9
22
21
N02BE01
ATC
paracetamol; systemic, rectal
3.2
11.8
289
2341
ZZA50
NOMESCO Finland
Full thickness skin graft
67.4
11.7
13
*
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
23.9
11.7
16
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
11.6
56
180
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
11.5
11
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
+∞
11.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
S29
ICPC
Skin symptom/complaint other
2.9
11.4
80
332
XQ848
NOMESCO Finland
Dermatological photography
8.1
11.4
25
33
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.9
11.2
25
34
WX110
NOMESCO Finland
Local anesthesy
2.2
11.0
202
1376
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.9
10.9
72
288
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
22.4
10.8
15
7
XX3DW
NOMESCO Finland
Time consuming IT work
5.1
10.6
33
70
8070/3-C44.2
ICD-O-3
Squamous cell carcinoma, NOS, of external ear
+∞
10.5
10
*
C44.59
ICD-10 Finland
Malignant tumor of the skin on the trunk other or unspecified histology
+∞
10.5
10
*
8070/3-C44.4
ICD-O-3
Squamous cell carcinoma, NOS, of skin of scalp and neck
+∞
10.5
10
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
10.5
10
*
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
+∞
10.5
10
*
8070/3-C44.7
ICD-O-3
Squamous cell carcinoma, NOS, of skin of lower limb and hip
+∞
10.5
10
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
10.1
10.4
20
21
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
10.3
137
798
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.5
10.0
90
430
L04AX01
ATC
azathioprine; systemic
5.9
9.9
27
49
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
20.8
9.9
14
7
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.8
9.7
27
50
WF002
NOMESCO Finland
Radical radiotherapy
56.7
9.7
11
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
56.7
9.7
11
*
115
Kela drug reimbursment
Breast cancer
+∞
9.4
9
*
8070/3-C44.6
ICD-O-3
Squamous cell carcinoma, NOS, of skin of upper limb and shoulder
+∞
9.4
9
*
8070/3-C44.5
ICD-O-3
Squamous cell carcinoma, NOS, of skin of trunk
+∞
9.4
9
*
A11CC03
ATC
alfacalcidol; systemic
7.1
9.3
22
33
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.2
87
426
XKD00
NOMESCO Finland
Uroflowmetry
2.5
9.0
77
357
D07AB08
ATC
desonide; topical
3.0
8.8
53
197
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
8.7
34
92
TQW40
NOMESCO Finland
Remowal of suture of skin
4.5
8.7
30
72
-54
ICPC
Repair/fix-suture/cast/prosth device
6.3
8.6
22
37
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
92.3
8.4
9
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
13.2
8.4
14
11
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
8.4
8
*
D04.0
ICD-10 Finland
Carcinoma in situ: Skin of lip
+∞
8.4
8
*
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
+∞
8.4
8
*
WZC30
NOMESCO Finland
Teaching
3.3
8.3
42
140
D06BX02
ATC
ingenol mebutate; topical
8.5
8.2
17
21
137
Kela drug reimbursment
Uraemia requiring dialysis
17.7
8.1
12
7
B01AB05
ATC
enoxaparin; parenteral
2.1
8.1
111
639
QAA99
NOMESCO Finland
Other local destruction of skin of head or neck
34.2
8.1
10
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
7.9
44
155
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
13.5
7.9
13
10
A04AA01
ATC
ondansetron; systemic, rectal
7.0
7.7
18
27
A46
ICD-10 Finland
Erysipelas
2.4
7.6
71
340
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
10.4
7.6
14
14
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
7.6
71
341
JN4AD
NOMESCO Finland
Body CT examination
5.3
7.6
22
44
S21
ICPC
Skin texture symptom/complaint
2.6
7.5
57
247
L03AA02
ATC
filgrastim; parenteral
81.8
7.4
8
*
QXA05
NOMESCO Finland
Skin division, unspecified location
81.8
7.4
8
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
81.8
7.4
8
*
H02AB02
ATC
dexamethasone; systemic
13.8
7.4
12
9
Z49.1
ICD-10 Finland
Extracorporeal dialysis
13.8
7.4
12
9
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
11.2
7.4
13
12
TK800
NOMESCO Finland
Hemodialysis
9.7
7.4
14
15
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.0
7.3
19
33
8090/3-C44.7
ICD-O-3
Basal cell carcinoma, NOS, of skin of lower limb and hip
+∞
7.3
7
*
205
Kela drug reimbursment
Chronic hypertension
1.9
7.3
141
921
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.3
7.2
36
119
DHB00
NOMESCO Finland
Excision of lesion of external nose
30.7
7.2
9
*
B01AB10
ATC
tinzaparin; parenteral
4.4
7.2
25
61
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
7.1
152
1028
C02CA01
ATC
prazosin; oral
5.4
7.1
20
39
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.5
6.9
14
17
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
11.3
6.8
12
11
UJF32
NOMESCO Finland
Coloscopy
2.0
6.8
96
554
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
40.9
6.8
8
*
UKC02
NOMESCO Finland
Cystoscopy
2.2
6.6
69
348
ZXC10
NOMESCO Finland
Use of laser
7.1
6.6
15
22
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
5.5
6.6
18
34
SPAT1325
SPAT
Vaccination
1.8
6.5
144
979
H02AB04
ATC
methylprednisolone; systemic
2.3
6.4
60
288
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
71.1
6.4
7
*
L02BB03
ATC
bicalutamide; oral
71.1
6.4
7
*
WXQ99
NOMESCO Finland
Other light therapy
71.1
6.4
7
*
S82
ICPC
Naevus/mole
2.7
6.4
42
167
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.8
6.4
15
23
HA1AA
NOMESCO Finland
X-ray mammography
6.8
6.4
15
23
J05AB01
ATC
aciclovir; systemic
2.2
6.4
68
348
SPAT1312
SPAT
General health counselling
1.9
6.4
111
692
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
11.3
6.3
11
10
L57.9
ICD-10 Finland
Skin changes due to chronic exposure to nonionizing radiation, unspecified
18.4
6.3
9
5
XJH00
NOMESCO Finland
Transanal ultrasonography
3.0
6.3
35
124
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
+∞
6.3
6
*
7151
FHL
Kidney transplantation
+∞
6.3
6
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
6.3
6
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
+∞
6.3
6
*
C44.10
ICD-10 Finland
Malignant tumor of the skin of the eyelids including the corner of the eye without histology
+∞
6.3
6
*
H26.3
ICD-10 Finland
Drug-induced cataract
27.2
6.3
8
*
L85.80
ICD-10 Finland
Hudhorn
27.2
6.3
8
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
5.5
6.2
17
32
B03XA02
ATC
darbepoetin alfa; parenteral
7.9
6.2
13
17
B02.9
ICD-10 Finland
Zoster without complication
3.4
6.2
28
87
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
5.1
6.1
18
37
S15
ICPC
Foreign body in skin
3.6
6.1
26
77
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
6.2
6.1
15
25
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
6.0
45
192

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
162
193
13.58
136.15
2.1
1.1
—
—
—
0
0
296
835
11.31
118.27
5.4
1.6
—
—
—
0
0
76
63
14.72
78.56
1.4
1.2
—
—
—
0
0
52
111
5.25
23.65
1.4
1.3
—
—
—
0
0
290
1860
3.13
22.60
5.7
4.2
6.8
6.9
mmol/l
0.72
279
1728
33
48
7.41
21.98
4.2
2.5
60.1
61.0
%
0.10
33
48
32
46
7.48
21.53
3.2
2.1
5.2
4.9
e9/l
0.18
32
46
258
1619
2.73
19.74
10.0
5.2
1.2
1.2
mmol/l
0.40
193
1373
64
186
3.92
19.61
4.6
3.8
0.3
0.3
%
0.02
23
35
122
530
2.89
19.44
6.3
4.2
—
—
—
0
0
66
202
3.72
18.75
4.7
3.7
0.0
0.1
%
0.24
25
42
211
1234
2.53
18.16
17.9
8.4
0.0
0.0
e9/l
0.23
183
1000
75
256
3.38
18.00
8.5
2.9
1.2
1.2
mmol/l
0.19
63
212
62
188
3.73
17.82
4.8
3.8
0.1
0.0
%
0.28
23
36
66
209
3.59
17.78
4.9
3.6
0.6
0.8
%
0.41
25
46
232
1429
2.52
17.69
8.5
4.9
0.2
0.2
e9/l
1.52
202
1220
225
1375
2.49
17.33
6.5
3.5
34.1
34.8
g/l
1.07
212
1251
225
1376
2.49
17.29
8.3
4.7
0.0
0.0
e9/l
1.50
199
1166
224
1370
2.48
17.17
8.3
4.7
0.6
0.6
e9/l
0.27
199
1152
88
343
3.02
16.84
2.5
1.7
—
—
—
0
0
225
1393
2.44
16.58
8.4
4.8
2.9
1.8
e9/l
1.06
202
1198
175
970
2.45
16.51
5.0
3.1
67.5
135.9
e6/l
0.42
150
749
240
1532
2.46
16.48
12.1
5.5
4.2
4.5
e9/l
1.14
220
1307
168
920
2.44
16.21
6.5
3.9
—
—
—
0
0
232
1477
2.39
15.76
7.1
3.5
12.3
12.2
umol/l
0.11
219
1365
190
1116
2.36
15.45
5.5
3.6
298.1
120.9
e6/l
0.84
159
802
165
917
2.38
15.18
9.5
4.9
—
—
—
0
0
309
2264
2.71
15.04
10.8
5.0
81.3
78.2
u/l
0.29
298
2054
161
900
2.34
14.46
5.0
3.0
0.4
0.5
e6/l
0.40
135
678
135
699
2.42
14.44
4.5
2.4
3.9
5.2
e6/l
0.87
125
597
32
69
4.96
14.27
5.3
3.2
—
—
—
0
0
67
245
3.09
14.20
8.4
3.7
—
—
—
0
0
128
652
2.43
14.16
4.6
2.6
502.6
547.1
mosm/kgh2o
2.15
115
530
204
1274
2.25
13.90
9.5
4.9
2.6
2.9
%
1.71
193
1150
153
853
2.30
13.67
2.9
2.1
—
—
—
0
0
199
1237
2.23
13.64
9.6
4.9
0.6
0.6
%
0.67
188
1122
204
1282
2.23
13.60
9.8
5.1
9.0
8.9
%
0.30
194
1163
299
2211
2.47
13.32
5.7
4.2
17.6
14.1
mm/h
2.13
272
1975
217
1406
2.21
13.31
16.5
11.7
1.3
1.4
inr
0.72
86
391
205
1300
2.21
13.25
9.6
5.1
25.9
25.7
%
0.08
194
1170
223
1463
2.21
13.22
9.8
4.8
1.2
1.2
mmol/l
0.07
194
1283
358
2904
3.61
13.17
28.7
15.0
24.3
26.5
mg/l
0.62
321
2308
176
1065
2.18
12.64
4.2
2.1
2.3
2.4
mmol/l
0.75
157
859
197
1257
2.14
12.23
5.0
3.7
—
—
—
0
0
366
3048
3.92
12.09
15.4
9.3
22.0
23.3
u/l
1.13
355
2879
148
854
2.18
11.82
5.1
2.9
—
—
—
0
0
199
1287
2.11
11.79
8.9
4.9
58.6
59.0
%
0.15
188
1174
50
173
3.17
11.56
2.5
1.3
3.1
4.6
ug/l
0.42
42
136
336
2692
2.71
11.46
5.1
4.6
2.0
2.0
mu/l
0.27
296
2368
372
3154
4.36
11.44
39.8
22.1
228.8
238.1
e9/l
1.82
366
3047
372
3155
4.35
11.42
39.8
22.1
4.2
4.4
e12/l
7.91
363
3033
372
3156
4.34
11.39
39.9
22.1
7.7
6.9
e9/l
1.34
364
3033
197
1283
2.07
11.31
3.5
3.2
2500.7
1941.6
ng/l
0.79
180
1109
15
6
25.89
11.22
29.7
34.8
5.9
6.8
ug/l
—
10
6
289
2178
2.24
11.18
4.1
3.6
15.2
15.1
pmol/l
0.05
258
1907
23
46
5.25
11.13
7.6
3.0
—
—
—
0
0
358
2978
3.27
11.09
27.1
14.7
—
—
—
0
0
280
2094
2.17
10.89
6.5
4.9
237.4
3663.0
e6/l
—
10
38
167
1036
2.06
10.82
4.8
4.4
—
—
—
0
0
92
456
2.33
10.47
4.2
2.4
22.9
21.9
%
0.28
78
383
216
1485
2.01
10.36
6.1
4.1
0.0
0.0
estimate
0.00
71
252
155
953
2.03
10.14
9.3
3.1
7.4
7.4
ph
0.18
49
152
339
2778
2.60
10.11
8.1
6.8
41.5
41.3
mmol/mol
0.14
303
2506
215
1490
1.98
9.93
7.7
5.4
0.0
0.0
estimate
0.00
68
241
211
1453
1.98
9.92
5.4
4.2
48.4
66.7
ng/l
0.38
183
1135
186
1231
1.97
9.78
3.8
2.8
154.2
135.3
ug/l
0.69
168
1099
280
2136
2.08
9.75
7.0
4.4
—
—
—
0
0
217
1515
1.97
9.74
6.1
4.1
0.0
0.0
estimate
0.00
67
245
89
451
2.26
9.54
4.4
2.2
0.8
0.8
mmol/l
1.02
82
412
94
489
2.21
9.45
4.2
2.3
2.2
2.2
g/l
0.47
82
444
17
30
5.88
9.35
4.6
3.0
1.2
0.5
%
0.85
12
22
150
934
1.98
9.30
2.5
2.3
3.5
3.1
mg/l
1.01
130
775
86
436
2.24
9.19
2.2
1.8
—
—
—
0
0
28
77
3.84
9.17
7.0
3.5
3.1
2.7
mmol/l
0.44
22
46
128
761
2.01
9.00
6.8
3.7
—
—
—
0
0
177
1180
1.91
8.86
5.2
3.9
—
—
—
0
0
100
550
2.10
8.65
4.2
2.3
12.4
12.4
umol/l
0.01
86
492
48
191
2.72
8.61
2.1
1.4
—
—
—
0
0
345
2913
2.51
8.53
6.1
5.5
2.4
2.5
mmol/l
2.41
307
2591
276
2155
1.94
8.21
5.7
4.4
—
—
—
0
0
336
2822
2.31
8.11
5.7
4.8
4.3
4.4
mmol/l
0.87
300
2505
24
66
3.81
7.86
2.7
2.1
14.4
15.5
%
0.63
14
34
44
178
2.66
7.64
2.4
1.4
—
—
—
0
0
331
2783
2.20
7.64
5.5
4.8
1.5
1.4
mmol/l
1.29
292
2453
128
802
1.88
7.50
4.7
2.6
4202.4
10573.4
umol/l
0.79
108
666
132
837
1.87
7.44
7.0
4.3
0.0
0.0
estimate
0.00
67
237
36
133
2.88
7.41
2.4
1.4
1.5
1.1
g/l
0.42
30
121
143
932
1.84
7.37
3.1
2.1
52.9
57.8
u/l
1.24
125
849
124
773
1.88
7.36
4.8
3.6
—
—
—
0
0
12
19
6.48
7.28
1.2
1.2
—
—
—
0
0
321
2690
2.06
7.13
5.2
4.3
1.2
1.2
mmol/l
0.81
281
2334
62
319
2.12
6.27
1.7
1.4
—
—
—
0
0
15
36
4.29
5.87
3.8
3.1
—
—
—
0
0
49
236
2.23
5.83
2.2
1.4
—
—
—
0
0
34
139
2.58
5.79
1.9
1.6
0.8
2.4
ug/l
0.89
29
115
53
265
2.16
5.76
1.3
1.2
—
—
—
0
0
98
613
1.80
5.56
1.9
1.7
1.5
1.3
mg/l
0.29
79
477
11
21
5.36
5.55
3.6
2.5
76.8
52.6
%
—
6
14
20
62
3.35
5.52
2.5
2.7
—
—
—
0
0
9
8
11.48
5.31
1.6
1.0
—
—
—
0
0
156
1122
1.65
5.29
4.4
3.4
—
—
—
0
0
78
463
1.85
5.22
2.4
2.2
1.5
1.7
%
1.61
69
404
152
1091
1.64
5.17
2.9
2.1
189.9
236.1
u/l
0.47
143
1011
331
2900
1.90
5.12
6.3
5.1
6.1
6.2
mmol/l
0.32
291
2549
157
1140
1.63
5.08
5.6
3.9
11.9
7.7
mg/mmol
0.48
99
725
33
143
2.43
5.00
1.5
1.3
—
—
—
0
0
289
2446
1.69
4.92
24.9
16.9
36.7
38.6
%
1.69
149
1439
120
826
1.65
4.74
1.9
1.8
442.3
17781588.8
pmol/l
0.80
92
658
26
103
2.63
4.73
3.2
3.6
0.7
0.9
nmol/l
1.56
20
82
99
654
1.69
4.56
8.9
4.1
—
—
—
0
0
166
1250
1.57
4.47
5.9
4.2
6.5
2.3
ug/l
0.58
140
1100
146
1069
1.58
4.43
3.9
3.1
189.2
215.3
mg/l
0.06
96
672
60
345
1.87
4.42
5.0
3.1
2.0
2.2
mmol/l
0.25
54
277
37
180
2.17
4.32
3.2
2.3
1.1
1.1
%
0.32
37
180
14
41
3.50
4.22
2.1
1.5
86.4
90.0
%
0.70
14
41
17
57
3.07
4.17
1.8
1.2
—
—
—
0
0
32
151
2.22
4.03
4.9
3.8
—
—
—
0
0
45
244
1.95
3.95
3.1
1.3
—
—
—
0
0
99
677
1.62
3.93
3.1
2.3
2.5
2.5
mmol/l
1.20
92
570
144
1080
1.53
3.81
3.9
3.0
6.2
7.1
mmol/l
2.70
113
890
18
66
2.81
3.81
1.3
1.2
329.3
316.5
ug/g
—
9
36
11
30
3.74
3.66
1.7
1.3
—
—
—
0
0
127
934
1.53
3.66
1.7
1.6
23.2
20.0
nmol/l
1.04
108
785
190
1525
1.48
3.55
2.2
2.2
96.5
92.7
pmol/l
0.49
100
796
58
353
1.75
3.55
4.0
2.5
56.7
67.0
e9/l
1.99
43
285
22
93
2.45
3.55
4.9
2.3
67.1
52.7
ug/min
0.14
15
57
33
167
2.07
3.51
1.8
1.8
1.4
1.6
g/l
0.56
27
144
6
6
10.13
3.51
1.5
1.0
13.3
15.7
u/ml
—
6
6
23
102
2.33
3.36
2.9
1.3
62.0
46.2
mg/l
0.56
15
83
23
102
2.33
3.36
2.9
1.3
28.8
31.6
mg/l
0.15
15
83
18
71
2.61
3.34
3.1
1.3
—
—
—
0
0
68
443
1.65
3.25
1.7
1.2
3.0
2.7
g/l
0.38
47
232
46
269
1.80
3.22
7.5
5.8
—
—
—
0
0
8
15
5.42
3.20
1.4
1.2
—
—
—
0
0
39
217
1.89
3.19
4.1
3.9
7.4
7.4
ph
1.51
11
26
9
20
4.58
3.13
1.4
1.4
—
—
—
0
0
40
226
1.86
3.13
1.7
1.5
—
—
—
0
0
11
34
3.30
3.08
2.3
1.3
—
—
—
0
0
5
5
10.10
2.98
2.8
1.2
—
—
—
0
0
15
58
2.65
2.91
1.2
1.4
52.9
61.3
mmol/l
—
9
45
32
173
1.93
2.87
4.3
2.6
0.4
0.2
e6/l
0.37
32
165
5
6
8.42
2.75
1.4
1.0
—
—
—
0
0
6
10
6.07
2.70
1.5
1.7
—
—
—
0
0
12
43
2.85
2.67
1.6
1.4
30.5
25.0
g/l
0.96
12
37
14
56
2.56
2.56
3.5
1.8
64.1
64.2
%
0.01
14
56
91
668
1.47
2.55
3.6
2.8
0.7
0.8
ug/l
0.89
64
484
10
33
3.08
2.54
1.9
1.3
—
—
—
0
0
9
26
3.52
2.49
5.3
2.8
—
—
—
0
0
19
90
2.17
2.43
4.3
3.8
—
—
—
0
0
21
106
2.04
2.30
1.6
1.3
—
—
—
0
0
8
23
3.53
2.28
1.6
1.3
—
—
—
0
0
7
19
3.73
2.16
1.1
1.2
—
—
—
0
0
6
14
4.33
2.16
1.0
1.1
—
—
—
0
0
6
15
4.04
2.04
2.0
2.2
—
—
—
0
0
12
50
2.44
2.04
2.3
3.1
—
—
—
0
0
9
32
2.85
2.01
2.4
1.4
—
—
—
0
0
9
32
2.85
2.01
2.4
1.4
—
—
—
0
0
9
32
2.85
2.01
2.4
1.4
—
—
—
0
0
9
32
2.85
2.01
2.4
1.4
—
—
—
0
0
5
11
4.59
1.94
3.0
1.0
—
—
—
0
0
94
732
1.37
1.88
1.7
1.6
1.2
1.2
mmol/l
0.22
70
593
49
338
1.51
1.87
6.3
3.7
—
—
—
0
0
68
502
1.43
1.85
1.2
1.2
0.8
1.6
u/ml
0.94
18
128
106
845
1.35
1.82
2.2
1.8
1373.1
1153.6
nmol/l
1.28
81
631
38
249
1.58
1.81
3.1
3.7
—
—
—
0
0
15
74
2.07
1.77
3.4
2.2
—
—
—
0
0
16
81
2.02
1.77
1.1
1.2
—
0.2
—
0
9
54
385
1.47
1.76
2.2
2.6
6.0
6.1
ug/l
0.02
44
333
42
284
1.54
1.76
7.5
3.5
160.7
87.5
ng/l
1.01
35
240
8
30
2.70
1.73
1.9
1.1
—
—
—
0
0
5
13
3.88
1.72
1.0
1.0
—
—
—
0
0
24
142
1.74
1.69
2.4
1.9
289.8
374.0
ug/l
0.31
24
130
6
19
3.19
1.66
1.2
1.1
—
—
—
0
0
7
25
2.83
1.65
1.4
1.0
—
—
—
0
0
35
234
1.54
1.56
2.5
1.9
118.5
171.3
ug/g
0.72
27
176
8
33
2.45
1.54
1.0
1.3
—
—
—
0
0
5
15
3.36
1.53
1.2
1.1
—
—
—
0
0
11
51
2.19
1.52
2.2
1.7
—
—
—
0
0
54
400
1.41
1.46
1.3
1.2
—
—
—
0
0
7
28
2.53
1.46
5.0
2.7
—
—
—
0
0
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
7
29
2.44
1.40
2.9
1.7
—
—
—
0
0
5
17
2.96
1.36
1.0
1.8
5.6
3.7
u/field
—
5
11
45
329
1.42
1.32
1.3
1.3
535.4
497.7
titre
0.06
13
79
9
43
2.12
1.31
1.1
1.1
—
—
—
0
0
90
735
1.29
1.29
4.7
4.0
—
—
—
0
0
5
18
2.80
1.29
2.2
1.3
15.3
16.8
ug/l
—
5
18
53
401
1.37
1.28
4.9
5.2
1.7
1.6
mmol/l
0.13
39
308
29
196
1.52
1.26
2.2
2.5
—
—
—
0
0
5
19
2.65
1.22
1.2
1.9
—
—
—
0
0
5
19
2.65
1.22
1.2
1.6
—
—
—
0
0
18
109
1.68
1.21
3.2
1.8
—
—
—
0
0
43
321
1.38
1.14
5.1
3.1
—
—
—
0
0
71
573
1.29
1.12
44.4
30.4
1.3
1.4
inr
—
10
71
7
32
2.21
1.08
1.9
1.5
—
—
—
0
0
7
34
2.08
1.03
1.1
1.1
—
—
—
0
0
23
157
1.49
0.98
5.1
4.1
—
—
—
0
0
34
251
1.39
0.98
1.6
1.6
—
—
—
0
0
11
62
1.80
0.95
3.1
2.1
13.5
12.2
mg/l
0.23
11
56
29
210
1.41
0.93
5.9
3.8
—
—
—
0
0
27
193
1.43
0.93
4.8
2.7
26.1
25.4
mmol/l
0.70
27
188
5
104
0.47
0.90
2.6
4.9
1.6
1.2
mmol/l
—
5
94
75
630
1.24
0.87
1.5
1.3
—
—
—
0
0
19
132
1.46
0.77
2.3
2.5
4.4
4.2
pmol/l
0.46
14
117
5
25
2.01
0.73
1.4
1.9
—
—
—
0
0
5
26
1.93
0.71
1.2
1.4
—
—
—
0
0
5
27
1.86
0.68
2.4
1.3
—
—
—
0
0
17
119
1.45
0.68
7.2
4.6
—
—
—
0
0
13
86
1.53
0.67
1.7
1.5
—
—
—
0
0
7
44
1.60
0.65
1.0
1.1
—
—
—
0
0
5
29
1.73
0.64
2.8
1.9
513.2
324.3
mu/l
—
5
29
8
53
1.52
0.58
2.3
1.8
—
—
—
0
0
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
17
124
1.39
0.56
1.5
2.0
—
—
—
0
0
9
64
1.42
0.52
2.6
2.4
—
—
—
0
0
9
65
1.39
0.51
2.6
2.4
104.6
105.4
mmol/l
—
9
65
9
65
1.39
0.51
2.6
2.4
4.2
4.1
mmol/l
—
9
65
17
128
1.34
0.48
12.8
13.0
—
—
—
0
0
51
442
1.18
0.46
1.2
1.3
19.3
39.8
iu/ml
2.44
18
142
12
86
1.41
0.45
2.5
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.1
334.6
306.7
pmol/l
—
5
24
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
8
57
1.41
0.42
1.1
1.1
32.0
18.6
u/l
—
8
50
10
70
1.44
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
38.4
—
0
8
0
16
0.00
0.41
0.0
4.1
—
31.0
—
0
10
5
36
1.39
0.38
1.4
1.2
—
—
nmol/l
—
0
0
5
36
1.39
0.38
1.4
1.2
—
—
—
0
0
12
158
0.75
0.38
8.6
7.4
—
—
—
0
0
9
71
1.27
0.36
1.4
1.1
—
—
—
0
0
6
43
1.40
0.35
3.7
1.6
—
—
—
0
0
13
100
1.31
0.34
1.4
1.2
—
—
—
0
0
77
711
1.10
0.30
6.1
4.6
1.0
1.0
kg/l
—
10
108
14
173
0.80
0.29
1.1
1.2
—
—
—
0
0
9
74
1.22
0.25
1.3
1.3
—
—
—
0
0
23
199
1.17
0.24
2.3
1.5
—
—
—
0
0
13
106
1.23
0.23
4.6
1.9
0.3
0.3
g/l
—
5
26
5
40
1.25
0.22
1.4
1.2
0.7
0.5
nmol/l
—
5
35
5
42
1.19
0.21
3.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
3.7
—
0
5
0
10
0.00
0.21
0.0
2.2
—
42.7
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
1.0
—
0
7
19
164
1.17
0.20
1.2
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
149.4
—
0
14
0
14
0.00
0.20
0.0
2.1
—
2.8
—
0
5
77
726
1.08
0.20
4.5
4.1
200.4
252.5
ng/l
0.21
71
629
7
58
1.21
0.18
1.3
1.3
—
—
—
0
0
7
58
1.21
0.18
1.7
1.2
4.2
4.1
mmol/l
—
7
53
17
149
1.15
0.16
3.2
3.7
0.7
0.9
%
2.11
17
144
10
83
1.21
0.15
1.4
2.3
—
—
—
0
0
17
151
1.13
0.13
3.2
3.6
1.2
1.6
%
1.86
17
146
22
236
0.93
0.08
3.1
3.0
—
—
—
0
0
7
64
1.10
0.08
1.9
1.3
43.3
369.1
e6/l
—
7
56
7
64
1.10
0.08
1.6
1.2
2.4
2.9
e6/l
—
7
54
43
415
1.04
0.05
1.1
1.3
4.1
12.3
u/ml
1.19
13
133
17
178
0.95
0.02
2.9
2.4
—
15.3
—
0
5
18
188
0.96
0.02
3.7
2.9
2.9
4.0
e9/l
—
10
125
15
154
0.97
0.00
1.9
1.3
—
51.4
—
0
10
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
5
57
0.88
0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
7
77
0.91
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
7.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
17.1
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_SKIN_NOS_EXALLC – Carcinoma in situ of skin, other sites/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).