No definition available.
Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)
C3_MANTLE_CELL_LYMPHOMA_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
489 |
4. Check minimum number of eventsNone |
489 |
5. Include endpointsNone |
489 |
6. Filter based on genotype QC (FinnGen only) |
489 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Non-follicular lymphoma
- Non-follicular lymphoma, hilmo, excluding all cancers
- Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)
- Primary_lymphoid and hematopoietic malignant neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 489 | 140 | 349 |
| Unadjusted period prevalence (%) | 0.12 | 0.05 | 0.15 |
| Median age at first event (years) | 67.26 | 64.62 | 68.32 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 276
- Matched controls
- 2758
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
323.0
275
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1282.6
304.4
248
19
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
152.6
132
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
143.6
125
*
XW000
NOMESCO Finland
Bone marrow biopsy
79.9
143.5
159
46
L03AA02
ATC
filgrastim; parenteral
+∞
139.8
122
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
127.1
112
*
A03FA01
ATC
metoclopramide; systemic, rectal
37.9
124.9
169
110
WW500
NOMESCO Finland
Blood transfusion
97.2
124.8
133
26
JN4BD
NOMESCO Finland
Extensive body CT
43.1
118.3
151
75
M04AA01
ATC
allopurinol; systemic
18.9
100.1
192
297
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
96.6
87
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
96.6
87
*
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
+∞
93.1
84
*
A04AA01
ATC
ondansetron; systemic, rectal
89.9
80.3
87
14
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
29.1
80.3
112
63
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
74.4
68
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
70.9
65
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
807.3
66.9
63
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
206.9
64.0
64
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
12.3
59.0
120
162
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
58.4
54
*
9673/3-C77.9
ICD-O-3
Mantle cell lymphoma of lymph node, NOS
+∞
57.3
53
*
JN6AD
NOMESCO Finland
CT of torso and neck
178.4
56.2
57
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
56.2
52
*
JN4AD
NOMESCO Finland
Body CT examination
25.9
55.6
79
42
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
49.5
54.3
65
17
1XC02
NOMESCO Finland
NA
222.4
54.1
54
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
588.3
51.1
49
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
296.1
49.8
49
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
49.5
49.3
59
15
9673/3-C77.8
ICD-O-3
Mantle cell lymphoma of lymph nodes of multiple regions
+∞
46.1
43
*
ZX120
NOMESCO Finland
Intravenous
11.5
45.4
92
115
H02AB06
ATC
prednisolone; systemic
6.8
45.1
212
905
H02AB02
ATC
dexamethasone; systemic
84.5
44.7
49
7
R50.9
ICD-10 Finland
Fever, unspecified
9.4
44.6
104
167
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
43.9
41
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
43.9
41
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
33.8
43.8
57
21
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
+∞
38.4
36
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
38.4
36
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
6.0
38.4
136
383
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.0
37.9
70
70
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
407.4
36.9
36
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
35.0
36.6
47
16
WF049
NOMESCO Finland
Radiotherapy of metastasis
381.3
34.7
34
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
34.1
32
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
132.9
33.5
35
*
Z51.5
ICD-10 Finland
Palliative care
24.3
33.1
47
23
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
33.0
31
*
J05AB11
ATC
valaciclovir; oral
7.1
30.4
82
154
ZX112
NOMESCO Finland
Subcutaneous
41.1
29.2
36
10
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
48.2
28.4
34
8
WW409
NOMESCO Finland
Other aferesis
+∞
26.5
25
*
WW402
NOMESCO Finland
Leucoferesis
+∞
26.5
25
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
25.4
24
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
25.4
24
*
WF002
NOMESCO Finland
Radical radiotherapy
142.8
25.0
26
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
24.6
174
853
N02AA05
ATC
oxycodone; systemic
5.7
24.0
76
171
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
37.1
23.9
30
9
WZC30
NOMESCO Finland
Teaching
6.3
23.5
68
136
XX3DW
NOMESCO Finland
Time consuming IT work
10.1
23.5
48
56
J01MA12
ATC
levofloxacin; systemic
4.4
22.9
100
316
ZX108
NOMESCO Finland
Inhalation
68.3
22.2
25
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
22.2
21
*
390
Kela drug reimbursment
Ibrutinib
+∞
22.2
21
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
22.2
21
*
TGC00
NOMESCO Finland
Bronchial lavation
13.2
22.0
39
34
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
124.8
21.9
23
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
11.3
21.5
41
42
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
65.3
21.2
24
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
14.7
20.8
35
27
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.1
20.7
72
178
212
Kela drug reimbursment
Gout
12.4
20.4
37
34
A02BC02
ATC
pantoprazole; systemic
3.7
20.1
215
1350
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
20.0
19
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
10.8
19.6
38
40
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
19.0
18
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
19.0
18
*
116
Kela drug reimbursment
Prostate cancer
+∞
19.0
18
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
203.0
18.8
19
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.7
17.6
42
63
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
45.2
17.5
21
5
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.0
17.0
49
96
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
16.8
16
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.3
16.4
66
186
L01XE27
ATC
[U] ibrutinib; oral
+∞
15.8
15
*
1AA09
NOMESCO Finland
NA
+∞
15.8
15
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
+∞
15.8
15
*
1512
Kela drug reimbursment
Ibrutinib
+∞
15.8
15
*
L01AA02
ATC
chlorambucil; oral
169.0
15.6
16
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
169.0
15.6
16
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.1
15.4
51
117
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
15.1
119
563
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
14.7
14
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
14.7
14
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
56.3
14.0
16
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
13.6
13
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
+∞
13.6
13
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
146.8
13.6
14
*
EMA10
NOMESCO Finland
Biopsy of tonsil
146.8
13.6
14
*
B01AB10
ATC
tinzaparin; parenteral
7.4
13.4
32
48
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
13.4
79
300
EP1AE
NOMESCO Finland
Neck ultrasound examination
8.2
13.1
29
39
WX110
NOMESCO Finland
Local anesthesy
2.6
13.0
187
1221
H02AB07
ATC
prednisone; oral
3.6
13.0
65
219
ZXE00
NOMESCO Finland
One hour or less
2.6
12.9
131
701
D70.89
ICD-10 Finland
Neutropenic splenomegaly
21.3
12.6
18
9
R06AE07
ATC
cetirizine; oral
2.7
12.3
116
592
GD1AD
NOMESCO Finland
Thorax CT examination
7.7
12.2
28
40
JN4CD
NOMESCO Finland
Very extensive body CT
14.3
12.1
20
15
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
48.9
12.0
14
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
48.9
12.0
14
*
EMB10
NOMESCO Finland
Tonsillectomy
15.6
12.0
19
13
D69.5
ICD-10 Finland
Secondary thrombocytopenia
67.8
11.7
13
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
11.5
11
*
L02BB03
ATC
bicalutamide; oral
+∞
11.5
11
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
26.3
11.3
15
6
TDM10
NOMESCO Finland
Puncture of maxillary antrum
8.8
11.0
23
28
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
10.6
80
351
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
114.1
10.5
11
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.5
10
*
L01EL01
ATC
ibrutinib; oral
+∞
10.5
10
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.4
10.3
38
97
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.0
10.3
33
73
R05
ICD-10 Finland
Cough
3.0
10.1
64
252
N02BE01
ATC
paracetamol; systemic, rectal
2.8
9.8
237
1885
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
18.3
9.5
14
8
ZXC50
NOMESCO Finland
Cryotherapy
13.0
9.5
16
13
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
9.4
9
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
+∞
9.4
9
*
9673/3-C80.9
ICD-O-3
Mantle cell lymphoma of unknown primary site
+∞
9.4
9
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
9.4
9
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
+∞
9.4
9
*
C81.3
ICD-10 Finland
Lymphocyte depleted classical Hodgkin lymphoma
+∞
9.4
9
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
9.4
9
*
B02.9
ICD-10 Finland
Zoster without complication
4.4
9.3
34
86
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
8.4
9.0
19
24
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
7.0
8.8
21
32
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
8.6
129
795
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
92.7
8.5
9
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
92.7
8.5
9
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
8.4
8
*
Z52.89
ICD-10 Finland
Donor of other organ or tissue
+∞
8.4
8
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
8.4
8
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
8.4
8
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
8.4
8
*
130
Kela drug reimbursment
Malignant tumour
+∞
8.4
8
*
Y77
ICPC
Malignant neoplasm prostate
+∞
8.4
8
*
WW200
NOMESCO Finland
Immunization
6.0
8.3
22
39
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.9
8.2
26
57
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
34.4
8.1
10
*
J01DB01
ATC
cefalexin; oral
2.3
8.0
221
1746
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
8.0
92
499
J01MA14
ATC
moxifloxacin; systemic
3.3
8.0
41
140
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
8.4
7.7
16
20
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.9
7.7
31
87
A07AA02
ATC
nystatin; oral
4.2
7.6
28
72
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
25.8
7.6
10
*
B01AB05
ATC
enoxaparin; parenteral
2.2
7.6
91
499
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
82.1
7.4
8
*
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
82.1
7.4
8
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
7.3
7
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
7.3
7
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
7.3
7
*
B72
ICPC
Hodgkin Lymphoma
+∞
7.3
7
*
127
Kela drug reimbursment
Transplant complication
16.3
7.3
11
7
J35.1
ICD-10 Finland
Hypertrophy of tonsils
30.9
7.2
9
*
L57.0
ICD-10 Finland
Actinic keratosis
3.6
7.0
31
94
UJF32
NOMESCO Finland
Coloscopy
2.2
7.0
82
443
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
41.0
6.8
8
*
A41.8
ICD-10 Finland
Other specified sepsis
9.0
6.6
13
15
J05AB01
ATC
aciclovir; systemic
2.4
6.6
58
274
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.5
89
511
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
71.4
6.4
7
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.8
6.4
15
23
A41.9
ICD-10 Finland
Sepsis, unspecified
4.8
6.4
20
44
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
6.3
37
138
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
6.3
27
80
ED1AA
NOMESCO Finland
Mandipular X-ray examination
18.5
6.3
9
5
N05CF01
ATC
zopiclone; oral
2.0
6.3
98
592
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
6.3
6
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
6.3
6
*
9673/3-C77.4
ICD-O-3
Mantle cell lymphoma of lymph nodes of inguinal region or leg
+∞
6.3
6
*
9673/3-C77.0
ICD-O-3
Mantle cell lymphoma of lymph nodes of head, face and neck
+∞
6.3
6
*
J02AC03
ATC
voriconazole; systemic
+∞
6.3
6
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
+∞
6.3
6
*
A79
ICPC
Malignancy NOS
+∞
6.3
6
*
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
SPAT1153
SPAT
Removal of sutures
2.0
6.2
92
547
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.1
6.2
33
116
A05AA02
ATC
ursodeoxycholic acid; oral
12.9
6.1
10
8
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.8
6.1
19
42
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_MANTLE_CELL_LYMPHOMA_EXALLC – Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).