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This is a non-core endpoint: only basic statistics are computed.

Melanoma in situ of other and unspecified parts of face

CD2_INSITU_MELANOMA_FACE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 360 182 178
Unadjusted period prevalence (%) 0.07 0.06 0.08
Median age at first event (years) 72.56 71.12 74.04

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
316
Matched controls
3158
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
+∞
323.0
305
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
213.5
259.8
251
56
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
552.9
87.7
83
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
17.8
85.7
147
147
ZZR00
NOMESCO Finland
Flap of skin
337.6
79.4
77
*
L57.0
ICD-10 Finland
Actinic keratosis
14.0
74.1
142
174
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
+∞
67.1
62
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
57.0
53
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
21.9
56.7
85
52
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
47.1
44
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
41.6
39
*
TQW99
NOMESCO Finland
Other minor procedure on skin
13.6
40.6
73
68
D03.30
ICD-10 Finland
Melanoma in situ on the lip
+∞
40.5
38
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
39.4
37
*
S18
ICPC
Laceration/cut
4.9
37.7
216
973
R23.8
ICD-10 Finland
Other and unspecified skin changes
6.4
37.1
114
257
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
22.1
33.5
49
26
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
32.9
31
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
31.8
30
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.2
31.7
62
67
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
52.1
31.3
37
8
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
31.2
31.1
41
15
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
+∞
29.6
28
*
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
15.0
29.1
49
38
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
30.5
25.0
33
12
ZZA50
NOMESCO Finland
Full thickness skin graft
+∞
23.2
22
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
22.9
23.1
33
16
D06BB10
ATC
imiquimod; topical
9.1
23.1
50
64
SPAT1153
SPAT
Removal of sutures
3.4
22.6
158
720
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
123.6
21.9
23
*
ZXC50
NOMESCO Finland
Cryotherapy
14.4
21.3
36
28
DHB00
NOMESCO Finland
Excision of lesion of external nose
82.5
21.0
23
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
10.5
20.3
40
43
115
Kela drug reimbursment
Breast cancer
+∞
20.0
19
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
18.9
18
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
14.1
18.9
32
25
S77
ICPC
Malignant neoplasm of skin
106.4
18.8
20
*
WX110
NOMESCO Finland
Local anesthesy
3.0
18.2
226
1436
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
70.8
17.9
20
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
17.6
16.9
26
16
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
16.8
16
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
16.8
16
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
179.0
16.7
17
*
L02BG04
ATC
letrozole; oral
179.0
16.7
17
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
179.0
16.7
17
*
ZXC20
NOMESCO Finland
Use of chemical agents
12.6
16.4
29
25
WF002
NOMESCO Finland
Radical radiotherapy
167.9
15.6
16
*
L82
ICD-10 Finland
Seborrhoeic keratosis
3.3
15.3
87
322
Z2221
NOMESCO Finland
Medical doctor
2.9
15.2
120
555
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
+∞
14.7
14
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
14.7
14
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
+∞
14.7
14
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
14.7
14
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.9
14.2
103
449
XX3DW
NOMESCO Finland
Time consuming IT work
6.5
14.1
37
63
HAB40
NOMESCO Finland
Wedge excision of mammary gland
78.6
13.7
15
*
130
Kela drug reimbursment
Malignant tumour
+∞
13.6
13
*
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
+∞
13.6
13
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
9.7
13.5
27
30
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
16.3
12.8
20
13
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
+∞
12.6
12
*
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
12.6
12
*
116
Kela drug reimbursment
Prostate cancer
+∞
12.6
12
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
12.6
12
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
12.6
12
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
135.1
12.5
13
*
D03.5
ICD-10 Finland
Melanoma in situ of trunk
135.1
12.5
13
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
9.9
12.2
24
26
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
8.9
12.0
25
30
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
17.2
11.8
18
11
S82
ICPC
Naevus/mole
3.5
11.8
58
190
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
67.5
11.7
13
*
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
+∞
11.5
11
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
11.5
11
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
11.5
11
*
ZZA00
NOMESCO Finland
Split skin graft
7.8
11.5
26
36
HA1AA
NOMESCO Finland
X-ray mammography
9.4
11.5
23
26
I78.1
ICD-10 Finland
Naevus, non-neoplastic
11.2
11.4
21
20
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
45.0
11.0
13
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
10.5
10
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.5
10
*
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
10.5
10
*
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
24.3
10.3
14
6
H02AB02
ATC
dexamethasone; systemic
13.7
10.3
17
13
ZQZ00
NOMESCO Finland
Treatment of several skin areas
41.5
10.0
12
*
J01DB01
ATC
cefalexin; oral
2.5
9.9
260
2053
WX002
NOMESCO Finland
Sedation and analgesia
2.4
9.8
93
460
ZXC15
NOMESCO Finland
Use of photodynamic technique
14.0
9.8
16
12
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
18.2
9.5
14
8
ZXE00
NOMESCO Finland
One hour or less
2.2
9.5
136
816
L02AE02
ATC
leuprorelin; implant, parenteral
103.0
9.5
10
*
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
22.5
9.4
13
6
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
+∞
9.4
9
*
L02BB03
ATC
bicalutamide; oral
+∞
9.4
9
*
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
+∞
9.4
9
*
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
+∞
9.4
9
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
9.4
9
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
11.2
9.4
17
16
S29
ICPC
Skin symptom/complaint other
2.6
9.2
72
319
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
37.8
9.1
11
*
JN4AD
NOMESCO Finland
Body CT examination
6.0
8.6
23
41
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
92.4
8.5
9
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
8.4
8
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
8.4
8
*
C43
ICD-10 Finland
Malignant melanoma of skin
+∞
8.4
8
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
8.4
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
8.4
8
*
Y77
ICPC
Malignant neoplasm prostate
46.1
7.7
9
*
S21
ICPC
Skin texture symptom/complaint
2.7
7.7
54
223
DAB00
NOMESCO Finland
Excision of lesion of auricle
18.9
7.7
11
6
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
18.9
7.7
11
6
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
7.6
125
775
R4110
NOMESCO Finland
Physiotherapy
2.1
7.5
95
528
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
13.8
7.4
12
9
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
7.4
135
870
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
+∞
7.3
7
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
+∞
7.3
7
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
7.3
7
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
+∞
7.3
7
*
8742/2-C44.3
ICD-O-3
Lentigo maligna of skin of other and unspecified parts of face
+∞
7.3
7
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
7.3
7
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
7.3
7
*
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
+∞
7.3
7
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
7.2
52
218
D22
ICD-10 Finland
Melanocytic naevi
6.3
7.2
18
30
WX402
NOMESCO Finland
General anaesthesia
2.7
7.1
48
195
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.1
87
476
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.3
6.9
24
59
A98
ICPC
Health maint/preventive medicine
3.0
6.8
296
2631
A04AA02
ATC
granisetron; systemic, transdermal
40.9
6.8
8
*
JN4BD
NOMESCO Finland
Extensive body CT
3.6
6.7
29
86
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
6.7
161
1131
S26
ICPC
Fear of cancer of skin
12.6
6.6
11
9
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
7.1
6.6
15
22
Z3231
NOMESCO Finland
Registered nurse
2.0
6.6
97
570
A04AA01
ATC
ondansetron; systemic, rectal
5.4
6.4
18
35
TQW40
NOMESCO Finland
Remowal of suture of skin
3.2
6.4
32
107
D06BX02
ATC
ingenol mebutate; topical
7.3
6.3
14
20
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
7.3
6.3
14
20
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
+∞
6.3
6
*
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
+∞
6.3
6
*
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
+∞
6.3
6
*
8742/3-C44.3
ICD-O-3
Lentigo maligna melanoma of skin of other and unspecified parts of face
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
6.3
6
*
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
+∞
6.3
6
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
6.3
6
*
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
+∞
6.3
6
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
6.3
6
*
XQ848
NOMESCO Finland
Dermatological photography
5.6
6.2
17
32
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.1
6.2
82
461
H01.0
ICD-10 Finland
Blepharitis
4.2
6.2
22
55
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
8.9
6.1
12
14
F16
ICPC
Eyelid symptom/complaint
3.9
6.0
23
62

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_FACE_EXALLC – Melanoma in situ of other and unspecified parts of face

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).