No definition available.
Malignant neoplasm of vulva, excluding all cancers (controls excluding all cancers)
C3_VULVA_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
466 |
4. Check minimum number of eventsNone |
466 |
5. Include endpointsNone |
466 |
6. Filter based on genotype QC (FinnGen only) |
466 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of vulva, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 466 | 466 | - |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | - |
| Median age at first event (years) | 65.99 | 65.99 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 275
- Matched controls
- 2750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
116.9
166.8
173
39
ULA02
NOMESCO Finland
Kolposcopy
40.7
137.9
188
138
LFC00
NOMESCO Finland
Partial excision of vulva
2138.4
136.5
121
*
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
+∞
122.3
108
*
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
+∞
114.8
102
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
102.7
92
*
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
+∞
80.2
73
*
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
+∞
71.0
65
*
LFD10
NOMESCO Finland
Vulvectomy and excision of regional lymph nodes
+∞
68.7
63
*
B01AB10
ATC
tinzaparin; parenteral
26.6
64.2
91
50
128
Kela drug reimbursment
Cancers of female genital organs
+∞
58.5
54
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
55.0
54.6
64
15
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
+∞
51.7
48
*
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
+∞
49.5
46
*
ZZR00
NOMESCO Finland
Flap of skin
112.9
44.4
47
5
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
8.6
44.2
110
197
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
43.9
41
*
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
16.7
42.9
71
56
C51.00
ICD-10 Finland
Malignant tumor of the labium majus without histology
+∞
39.5
37
*
H02AB02
ATC
dexamethasone; systemic
41.2
38.7
48
14
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
38.4
36
*
WF002
NOMESCO Finland
Radical radiotherapy
206.2
35.7
36
*
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
+∞
35.2
33
*
JN4BD
NOMESCO Finland
Extensive body CT
14.5
35.0
61
53
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
56.5
33.5
39
8
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
33.0
31
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.9
32.6
149
534
LEB00
NOMESCO Finland
Biopsy of vagina
22.8
31.8
46
24
XX3DW
NOMESCO Finland
Time consuming IT work
11.2
29.6
58
64
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
23.8
28.8
41
20
D39.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other female genital organs
+∞
28.6
27
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
25.0
27.9
39
18
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.4
26.6
126
444
C51.04
ICD-10 Finland
Basal cell carcinoma of labium majus
+∞
26.5
25
*
N76.6
ICD-10 Finland
Ulceration of vulva
37.2
26.2
33
10
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
13.9
25.9
45
38
JN4AD
NOMESCO Finland
Body CT examination
14.3
25.6
44
36
8070/3-C51.1
ICD-O-3
Squamous cell carcinoma, NOS, of labium minus
+∞
25.4
24
*
8070/3-C51.0
ICD-O-3
Squamous cell carcinoma, NOS, of labium majus
+∞
25.4
24
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
25.4
24
*
D07AD01
ATC
clobetasol; topical
4.9
24.8
95
267
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
6.3
24.7
72
147
LFD00
NOMESCO Finland
Vulvectomy
+∞
24.3
23
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
6.1
24.2
72
150
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
71.4
23.3
26
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
71.4
23.3
26
*
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
10.8
22.9
45
49
A04AA01
ATC
ondansetron; systemic, rectal
15.2
21.7
36
27
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
40.8
21.2
26
7
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
+∞
21.1
20
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.4
21.0
87
259
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
119.1
20.9
22
*
A04AA02
ATC
granisetron; systemic, transdermal
119.1
20.9
22
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
226.4
20.9
21
*
C51.09
ICD-10 Finland
Malignant tumor of the labium majus, unspecified histology
+∞
20.0
19
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
20.0
19
*
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
20.6
19.1
28
15
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
19.0
18
*
8090/3-C51.9
ICD-O-3
Basal cell carcinoma, NOS, of vulva, NOS
+∞
19.0
18
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
17.9
17
*
130
Kela drug reimbursment
Malignant tumour
+∞
17.9
17
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
17.9
17
*
C77.4
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Inguinal and lower limb lymph nodes
+∞
17.9
17
*
115
Kela drug reimbursment
Breast cancer
+∞
16.8
16
*
C51.1
ICD-10 Finland
Malignant neoplasm: Labium minus
+∞
16.8
16
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
180.5
16.7
17
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
7.4
16.4
40
62
WX402
NOMESCO Finland
General anaesthesia
4.5
16.2
63
172
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
15.8
15
*
8542/3-C51.9
ICD-O-3
Paget disease, extramammary of vulva, NOS
+∞
15.8
15
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
15.8
15
*
B01AB05
ATC
enoxaparin; parenteral
3.0
15.7
125
597
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
40.6
15.6
19
5
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
14.7
14
*
Z51.5
ICD-10 Finland
Palliative care
10.3
14.3
28
30
N02AA05
ATC
oxycodone; systemic
3.6
13.7
68
228
N90.0
ICD-10 Finland
Mild vulvar dysplasia
36.1
13.7
17
5
8720/3-C51.9
ICD-O-3
Malignant melanoma, NOS, of vulva, NOS
+∞
13.7
13
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
13.7
13
*
C51.21
ICD-10 Finland
Squamous cell carcinoma of the clitoris
+∞
13.7
13
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
147.0
13.6
14
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
147.0
13.6
14
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
10.1
13.3
26
28
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
33.8
12.7
16
5
A04AD12
ATC
aprepitant; systemic
+∞
12.6
12
*
C51.0
ICD-10 Finland
Malignant neoplasm: Labium majus
+∞
12.6
12
*
8090/3-C51.0
ICD-O-3
Basal cell carcinoma, NOS, of labium majus
+∞
12.6
12
*
C51.89
ICD-10 Finland
Overall malignant tumor of the vulva, unspecified histology
+∞
12.6
12
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
12.6
12
*
C51.19
ICD-10 Finland
Adenocarcinoma of the labium minus, unspecified histology
+∞
12.6
12
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.3
12.4
38
80
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
48.9
12.0
14
*
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
67.9
11.7
13
*
LFE10
NOMESCO Finland
Plastic repair of vulva
67.9
11.7
13
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
67.9
11.7
13
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
67.9
11.7
13
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
11.5
11
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
11.5
11
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.5
11.5
23
26
HA1AA
NOMESCO Finland
X-ray mammography
6.0
11.0
30
55
LCA06
NOMESCO Finland
Biopsy of endometrium
3.4
10.9
57
197
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
29.4
10.8
14
5
C51.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of vulva
+∞
10.5
10
*
C51.13
ICD-10 Finland
Melanoma and labium minus
+∞
10.5
10
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
10.5
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.5
10
*
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
+∞
10.5
10
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
10.5
10
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
10.5
10
*
L02BG04
ATC
letrozole; oral
34.0
10.4
13
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.9
10.3
25
39
X77
ICPC
Malignant neopl genital female other
57.1
9.7
11
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.0
9.7
39
109
WZC30
NOMESCO Finland
Teaching
3.8
9.6
42
126
LFW96
NOMESCO Finland
Other operation on vulva or perineum
103.4
9.5
10
*
WW500
NOMESCO Finland
Blood transfusion
9.2
9.5
19
22
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
9.4
9
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
9.4
9
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
9.1
39
115
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
9.0
50
179
WX320
NOMESCO Finland
Spinalanesthesy
2.4
8.8
88
449
HAB40
NOMESCO Finland
Wedge excision of mammary gland
14.7
8.8
14
10
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
51.7
8.7
10
*
L03.3
ICD-10 Finland
Cellulitis of trunk
51.7
8.7
10
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
8.4
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
8.4
8
*
5702
FHL
Local lymph node removal (eg armpit, groin)
+∞
8.4
8
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
8.4
8
*
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
+∞
8.4
8
*
Z93.3
ICD-10 Finland
Colostomy status
+∞
8.4
8
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.9
8.2
22
40
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
34.5
8.1
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
8.0
64
288
A46
ICD-10 Finland
Erysipelas
2.7
7.9
59
256
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.6
7.8
26
61
ZXC40
NOMESCO Finland
Use of ultrasound
25.8
7.6
10
*
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
25.8
7.6
10
*
JFF23
NOMESCO Finland
Transversostomy
82.2
7.5
8
*
C50.99
ICD-10 Finland
Breast, unspecified
82.2
7.5
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.6
7.3
57
251
8477
FHL
Vulvectomy
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.3
7
*
QB4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in groin or genital area (from front)
+∞
7.3
7
*
1844A
ICD-9 Finland
Malignant neoplasm of other and unspecified female genital organs, Vulva, unspecified
+∞
7.3
7
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
7.3
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.2
74
375
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
7.2
68
335
D06BB10
ATC
imiquimod; topical
5.0
6.9
21
45
N90.4
ICD-10 Finland
Leukoplakia of vulva
17.2
6.8
10
6
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.7
67
334
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
9.0
6.6
13
15
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
71.4
6.5
7
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
71.4
6.5
7
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.8
6.4
17
31
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
6.3
32
109
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
6.3
6
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
6.3
6
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
6.3
6
*
YL1CD
NOMESCO Finland
Very extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
KCC30
NOMESCO Finland
Cystectomy with excision of female internal genital organs
+∞
6.3
6
*
C51.03
ICD-10 Finland
Melanoma and labium majus
+∞
6.3
6
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
6.3
6
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
6.3
6
*
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
+∞
6.3
6
*
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
27.4
6.3
8
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
6.2
105
658
J01CE08
ATC
benzathine benzylpenicillin; parenteral
12.9
6.1
10
8
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.0
6.1
14
21
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_VULVA_EXALLC – Malignant neoplasm of vulva, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).