Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)

C3_BONE_CARTILAGE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

671

6. Filter based on genotype QC (FinnGen only)

671

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 671 315 356
Unadjusted period prevalence (%) 0.13 0.11 0.16
Median age at first event (years) 55.90 55.37 56.38

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
289
Matched controls
2888
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
99.9
90
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
108.9
99.7
105
15
H02AB02
ATC
dexamethasone; systemic
88.3
71.7
78
12
JN4BD
NOMESCO Finland
Extensive body CT
27.3
64.2
90
47
L03AA02
ATC
filgrastim; parenteral
749.5
63.3
60
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
56.1
52
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
60.3
53.7
62
13
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
597.8
52.2
50
*
N02AA05
ATC
oxycodone; systemic
10.7
48.4
103
142
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
47.2
44
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
45.0
42
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
45.0
42
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.8
44.3
99
146
A04AA02
ATC
granisetron; systemic, transdermal
+∞
43.9
41
*
A04AA01
ATC
ondansetron; systemic, rectal
27.5
40.7
56
25
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
39.5
37
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
37.3
35
*
XX3DW
NOMESCO Finland
Time consuming IT work
16.1
36.8
61
47
JN4AD
NOMESCO Finland
Body CT examination
20.3
36.3
55
33
L03AA13
ATC
pegfilgrastim; parenteral
+∞
35.1
33
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
34.0
32
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.0
33.6
145
486
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
15.2
33.6
57
46
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
32.9
31
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
49.8
32.8
39
9
WF002
NOMESCO Finland
Radical radiotherapy
361.7
32.5
32
*
B01AB05
ATC
enoxaparin; parenteral
4.9
31.2
131
419
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
31.2
182
805
NF3AA
NOMESCO Finland
Femur X-ray examination
29.6
30.7
41
16
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
322.6
29.3
29
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
28.6
27
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.6
28.5
126
416
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
27.5
26
*
XW000
NOMESCO Finland
Bone marrow biopsy
15.9
27.4
45
33
N03AX16
ATC
pregabalin; oral
4.6
27.2
116
366
Z51.5
ICD-10 Finland
Palliative care
29.2
26.9
36
14
WW500
NOMESCO Finland
Blood transfusion
24.1
26.9
38
18
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.0
26.6
55
66
JN4CD
NOMESCO Finland
Very extensive body CT
49.4
26.1
31
7
R4110
NOMESCO Finland
Physiotherapy
4.3
26.0
125
439
TPX10
NOMESCO Finland
Implantation of vascular injection port
28.2
26.0
35
14
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
25.4
24
*
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
25.4
24
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
25.4
24
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
24.7
25.0
35
16
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
24.3
23
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
24.3
23
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
24.3
23
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
24.3
23
*
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
94.9
24.1
26
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
24.0
89
238
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.3
23.8
51
65
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
23.2
22
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
23.2
22
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.0
23.0
60
104
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
22.2
21
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
22.2
21
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
30.8
21.4
28
10
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
21.1
20
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
21.1
20
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
21.1
20
*
ZX120
NOMESCO Finland
Intravenous
7.1
20.3
52
87
B01AB10
ATC
tinzaparin; parenteral
9.2
20.1
43
54
NG4AA
NOMESCO Finland
Lower leg X-ray examination
12.7
20.1
36
32
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
20.0
19
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
21.3
20.0
29
15
GD1AD
NOMESCO Finland
Thorax CT examination
11.3
19.6
37
37
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
19.0
18
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
19.0
18
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
19.0
18
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
+∞
19.0
18
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.7
18.7
69
179
WX402
NOMESCO Finland
General anaesthesia
4.4
18.4
74
209
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
17.9
17
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.8
17.6
30
24
WZC30
NOMESCO Finland
Teaching
4.8
17.1
61
152
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
13.9
17.1
29
23
153
Kela drug reimbursment
Lenalidomid
+∞
16.8
16
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
+∞
16.8
16
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
7.9
16.8
39
56
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
179.9
16.7
17
*
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
63.7
15.9
18
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.0
15.8
45
86
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
15.8
15
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
15.8
15
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
15.8
15
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
15.8
15
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
15.8
15
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
6.7
15.0
39
66
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
84.5
14.7
16
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
14.7
14
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
14.7
14
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
14.7
14
*
C41.49
ICD-10 Finland
Malignant tumor of the pelvic bones, sacrum and coccyx other or unspecified histology
+∞
14.7
14
*
L04AX04
ATC
lenalidomide; oral
+∞
14.7
14
*
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
38.2
14.6
18
5
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
157.6
14.6
15
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
13.9
122
604
R50.9
ICD-10 Finland
Fever, unspecified
3.8
13.8
63
196
9101
FHL
Bone biopsy
+∞
13.6
13
*
L71
ICPC
Malignant neoplasm musculoskeletal
+∞
13.6
13
*
A04AD12
ATC
aprepitant; systemic
+∞
13.6
13
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
13.6
13
*
AA1AA
NOMESCO Finland
Head X-ray examination
146.6
13.6
14
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
146.6
13.6
14
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
9.7
13.0
26
29
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
52.5
13.0
15
*
N02BE01
ATC
paracetamol; systemic, rectal
3.3
12.9
253
1957
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
12.6
12
*
329
Kela drug reimbursment
Lenalidomide
+∞
12.6
12
*
9370/3-C41.4
ICD-O-3
Chordoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
12.6
12
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
12.6
12
*
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
12.6
12
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
6.0
12.6
35
65
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
12.4
12.5
22
19
GAE06
NOMESCO Finland
Excision of lesion of chest wall
135.6
12.5
13
*
N02AX02
ATC
tramadol; systemic, rectal
2.5
12.3
138
770
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
11.9
95
437
ZX112
NOMESCO Finland
Subcutaneous
20.0
11.7
17
9
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
67.8
11.7
13
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.0
11.6
32
59
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
11.5
11
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
+∞
11.5
11
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
11.5
11
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
11.5
11
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
11.5
11
*
TPX15
NOMESCO Finland
Removal of vascular injection port
124.7
11.5
12
*
TPH07
NOMESCO Finland
Cathetrisation of artery
4.1
11.4
45
123
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.6
11.3
53
168
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
22.5
10.8
15
7
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
5.1
10.7
34
74
ZXE40
NOMESCO Finland
More than seven and less than nine hours
9.7
10.7
21
23
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.6
10.5
24
34
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
10.5
127
721
C41.40
ICD-10 Finland
Pelvic bones, sacrum and coccyx
+∞
10.5
10
*
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.5
10
*
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
10.5
10
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.1
10.4
20
21
ZXD05
NOMESCO Finland
Urgent procedure
2.5
10.3
106
552
A02BC02
ATC
pantoprazole; systemic
2.3
10.3
184
1252
ZXE00
NOMESCO Finland
One hour or less
2.3
10.2
130
755
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
41.6
10.0
12
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.8
10.0
43
127
JN6AD
NOMESCO Finland
CT of torso and neck
27.1
9.9
13
5
PJA12
NOMESCO Finland
Sentinel node biopsy
56.9
9.7
11
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
56.9
9.7
11
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
56.9
9.7
11
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.5
9.7
34
83
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
9.5
70
301
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
9.4
9
*
9731/3-C41.3
ICD-O-3
Plasmacytoma, NOS, of rib, sternum, clavicle and associated joints
+∞
9.4
9
*
115
Kela drug reimbursment
Breast cancer
+∞
9.4
9
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
9.4
9
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
9.4
9
*
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
9.4
9
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
9.4
9
*
A79
ICPC
Malignancy NOS
+∞
9.4
9
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
9.4
9
*
HA1AA
NOMESCO Finland
X-ray mammography
10.0
9.4
18
19
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
8.2
9.3
20
26
J01MA12
ATC
levofloxacin; systemic
2.8
9.1
65
275
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
38.0
9.1
11
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
24.9
9.0
12
5
B01AB04
ATC
dalteparin; parenteral
6.5
8.8
22
36
L28
ICPC
Limited function/disability (L)
2.8
8.8
60
246
WX002
NOMESCO Finland
Sedation and analgesia
2.6
8.8
71
322
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
8.8
48
169
NB6AA
NOMESCO Finland
Humerus X-ray examination
12.1
8.7
15
13
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.6
8.6
39
120
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
28.5
8.5
11
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
28.5
8.5
11
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.9
8.5
35
99
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.3
8.5
31
79
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
92.6
8.5
9
*
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
92.6
8.5
9
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
8.4
80
395
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
8.4
59
247
J05AB01
ATC
aciclovir; systemic
2.6
8.4
69
316
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
8.4
8
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
8.4
8
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
8.4
8
*
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
8.4
8
*
9731/3-C41.2
ICD-O-3
Plasmacytoma, NOS, of vertebral column
+∞
8.4
8
*
C41.41
ICD-10 Finland
Osteosarcoma of the pelvic bones, sacrum and coccyx
+∞
8.4
8
*
WW402
NOMESCO Finland
Leucoferesis
+∞
8.4
8
*
NFA20
NOMESCO Finland
Exploration of hip joint or femur
+∞
8.4
8
*
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
8.4
8
*
NF3AD
NOMESCO Finland
Femur CT
+∞
8.4
8
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
8.4
8
*
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
+∞
8.4
8
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
8.4
8
*
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
8.4
8
*
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
8.4
8
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
8.4
8
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.5
8.2
17
21
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.0
8.2
32
87
NF1AA
NOMESCO Finland
Hip X-ray examination
3.8
8.1
34
98
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
34.4
8.1
10
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.2
8.0
30
78
R52.0
ICD-10 Finland
Acute pain
6.4
8.0
20
33
ZXA05
NOMESCO Finland
Left side
2.3
8.0
87
459
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.4
7.9
28
69
NG1AD
NOMESCO Finland
Knee CT examination
11.2
7.9
14
13
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
11.2
7.9
14
13
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.2
7.8
41
142
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
12.3
7.7
13
11
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
10.4
7.6
14
14
ZXA00
NOMESCO Finland
Right side
2.2
7.5
88
478
SPAT1153
SPAT
Removal of sutures
2.2
7.5
96
541
J05AB11
ATC
valaciclovir; oral
3.0
7.5
44
165
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
82.1
7.5
8
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
82.1
7.5
8
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
+∞
7.3
7
*
C40.10
ICD-10 Finland
Malignant tumor of the upper limb's short bones without histology
+∞
7.3
7
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
7.3
7
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
7.3
7
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
7.3
7
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
7.3
7
*
9680/3-C41.4
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
7.3
7
*
C41.3
ICD-10 Finland
Malignant neoplasm: Ribs, sternum and clavicle
+∞
7.3
7
*
WW409
NOMESCO Finland
Other aferesis
+∞
7.3
7
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
NK6AT
NOMESCO Finland
Bone biopsy with ultrasound guidance
+∞
7.3
7
*
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
16.3
7.3
11
7
9102
FHL
Trepanation or removal of the local bone process
20.6
7.2
10
5
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.0
7.1
27
72
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.9
7.1
22
48
M05BX04
ATC
denosumab; parenteral
6.1
7.0
18
31
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
7.0
34
111
S18
ICPC
Laceration/cut
2.0
7.0
125
803
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.8
6.7
21
46
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
6.4
6.6
16
26
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
71.3
6.4
7
*
HAC20
NOMESCO Finland
Total mastectomy
71.3
6.4
7
*
ZX121
NOMESCO Finland
Central venous catheter
71.3
6.4
7
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
71.3
6.4
7
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
71.3
6.4
7
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
18.5
6.3
9
5
H02AB09
ATC
hydrocortisone; systemic
7.3
6.3
14
20
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
+∞
6.3
6
*
C41.00
ICD-10 Finland
Malignant tumor of the skull or facial bone without histology
+∞
6.3
6
*
WX1DG
NOMESCO Finland
Very extensive total body MRI with high intensity magnet
+∞
6.3
6
*
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
C41.09
ICD-10 Finland
Malignant tumor of the skull or facial bones other or unspecified histology
+∞
6.3
6
*
C40.12
ICD-10 Finland
Chondrosarcoma of the short bones of the upper extremity
+∞
6.3
6
*
C40.23
ICD-10 Finland
Ewing's sarcoma in the long bones of the lower extremity
+∞
6.3
6
*
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
+∞
6.3
6
*
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
+∞
6.3
6
*
NGR40
NOMESCO Finland
Extensive excision of tumor of knee or lower leg with repair
+∞
6.3
6
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
6.3
6
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
6.3
6
*
GDA20
NOMESCO Finland
Excision of lesion of lung
+∞
6.3
6
*
NB4AA
NOMESCO Finland
Scapula X-ray examination
+∞
6.3
6
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
6.3
6
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
6.3
6
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
6.3
6
*
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
+∞
6.3
6
*
C40.93
ICD-10 Finland
Malignant tumor in unspecified locations in the bones and articular cartilage of the extremities
+∞
6.3
6
*
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
12.9
6.1
10
8
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
8.9
6.1
12
14
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
5.4
6.1
17
33
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.1
62
314
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
6.3
6.1
15
25

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_BONE_CARTILAGE_EXALLC – Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).