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Brain glioblastoma and astrocytoma, excluding all cancers (controls excluding all cancers)

Endpoint Browser PheWeb

C3_GBM_ASTROCYTOMA_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • HLP_C3_GBM
  • or HLP_C3_ASTROCYTOMA
578

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C71
  • Cause of death: ICD-9 — 191
  • Cause of death: ICD-8 — 191
  • Cancer registry: Topography ICD-O-3 — C71
  • Cancer registry: Morphology ICD-O-3 — 9400|9440
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

578

4. Check minimum number of events

None

578

5. Include endpoints

578

6. Filter based on genotype QC (FinnGen only)

578

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Brain glioblastoma and astrocytoma, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 578 248 330
Unadjusted period prevalence (%) 0.12 0.08 0.15
Median age at first event (years) 62.19 61.09 63.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
546
Matched controls
5459
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
1731.8
323.0
456
16
L01AX03
ATC
temozolomide; systemic
+∞
323.0
365
*
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
413
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
4044.9
323.0
413
*
N03AX14
ATC
levetiracetam; systemic
132.4
277.1
283
44
A04AA02
ATC
granisetron; systemic, transdermal
4378.9
257.4
228
*
WF002
NOMESCO Finland
Radical radiotherapy
3810.1
238.7
213
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
47.0
233.9
292
130
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
34.7
219.8
301
186
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
94.4
205.4
221
39
A03FA01
ATC
metoclopramide; systemic, rectal
23.1
199.2
323
321
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
407.9
198.3
188
7
WF003
NOMESCO Finland
Adjuvant radiotherapy
1153.2
176.4
163
*
Z51.5
ICD-10 Finland
Palliative care
84.9
169.7
186
33
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
+∞
167.5
152
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
148.9
136
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
1733.5
142.2
132
*
ZXC95
NOMESCO Finland
Use of surgical navigator
133.4
141.4
147
15
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
+∞
138.6
127
*
9440/3-C71.9
ICD-O-3
Glioblastoma, NOS, of brain, NOS
+∞
137.4
126
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
+∞
136.3
125
*
C71.13
ICD-10 Finland
Malignant tumor of frontal lobe grade IV glioma
+∞
135.1
124
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
1614.2
134.2
125
*
XX3DW
NOMESCO Finland
Time consuming IT work
25.8
128.2
185
106
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
120.4
111
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
39.8
114.4
145
49
A04AA01
ATC
ondansetron; systemic, rectal
46.0
111.0
136
39
9440/3-C71.2
ICD-O-3
Glioblastoma, NOS, of temporal lobe
+∞
110.2
102
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
1203.7
104.9
99
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
40.7
98.6
124
39
C71.2
ICD-10 Finland
Malignant neoplasm: Temporal lobe
+∞
97.9
91
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
96.8
90
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
42.5
92.4
115
34
9440/3-C71.1
ICD-O-3
Glioblastoma, NOS, of frontal lobe
+∞
92.4
86
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
1029.9
91.6
87
*
AA1AD
NOMESCO Finland
CT of head and brain
7.1
90.9
291
754
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
1001.8
89.3
85
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
+∞
85.7
80
*
C71.33
ICD-10 Finland
Malignant tumor of parietal lobe grade IV glioma
+∞
81.3
76
*
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
851.5
77.3
74
*
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
+∞
76.9
72
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
73.6
69
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.8
71.8
215
474
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
71.4
67
*
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
+∞
69.3
65
*
N03AF02
ATC
oxcarbazepine; oral
18.7
68.3
108
71
N03AX18
ATC
lacosamide; systemic
103.4
66.7
72
8
ZXC40
NOMESCO Finland
Use of ultrasound
187.1
64.5
66
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
13.1
62.4
115
109
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.9
61.4
267
884
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
12.2
59.9
114
115
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
644.7
59.9
58
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
325.2
58.5
58
*
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
+∞
58.4
55
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
8.0
56.5
140
225
N02AA05
ATC
oxycodone; systemic
7.2
52.5
141
253
WZC30
NOMESCO Finland
Teaching
7.4
51.3
134
230
WX882
NOMESCO Finland
High dependency care
16.3
50.9
84
60
9400/3-C71.9
ICD-O-3
Astrocytoma, NOS, of brain, NOS
+∞
50.8
48
*
9440/3-C71.3
ICD-O-3
Glioblastoma, NOS, of parietal lobe
+∞
49.7
47
*
9400/3-C71.1
ICD-O-3
Astrocytoma, NOS, of frontal lobe
+∞
48.7
46
*
N74
ICPC
Malignant neoplasm nervous system
+∞
48.7
46
*
C71.3
ICD-10 Finland
Malignant neoplasm: Parietal lobe
+∞
47.6
45
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
47.6
45
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
47.6
45
*
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
+∞
46.5
44
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
250.5
45.7
46
*
C71.83
ICD-10 Finland
Overall malignant tumor of the brain grade IV glioma
+∞
45.4
43
*
A02BC02
ATC
pantoprazole; systemic
4.0
45.0
425
2552
ZXM40
NOMESCO Finland
Use of fluorescent substance
238.7
43.6
44
*
XA800
NOMESCO Finland
Neuropsychological investigation
11.2
41.9
82
85
G40.9
ICD-10 Finland
Epilepsy, unspecified
12.8
41.7
76
68
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
+∞
41.2
39
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
32.4
40.4
53
18
WX402
NOMESCO Finland
General anaesthesia
5.0
40.2
148
380
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
40.1
38
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
18.2
39.6
62
38
N05CD08
ATC
midazolam; nasal, systemic
18.8
36.3
56
33
ZXE20
NOMESCO Finland
More than three and less than five hours
4.8
34.3
129
333
N03AB02
ATC
phenytoin; systemic
20.6
32.9
49
26
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
+∞
31.6
30
*
A28
ICPC
Limited function/disability NOS
4.2
31.0
133
387
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.8
30.3
151
502
WX872
NOMESCO Finland
Intensive care
7.6
29.6
72
107
C71.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of brain
+∞
29.4
28
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
29.4
28
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
29.4
28
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
46.5
29.0
35
8
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
32.9
28.5
37
12
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
28.4
27
*
C71.93
ICD-10 Finland
Malignant tumor in an unspecified localization in the brain grade IV glioma
+∞
28.4
27
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
28.4
27
*
A79
ICPC
Malignancy NOS
152.8
27.9
29
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
+∞
27.3
26
*
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
+∞
27.3
26
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
26.3
25
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
26.1
179
745
N05BA09
ATC
clobazam; oral
76.2
26.0
29
*
JN4BD
NOMESCO Finland
Extensive body CT
6.4
25.6
70
122
H53.4
ICD-10 Finland
Visual field defects
13.2
25.0
44
36
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
12.5
24.9
45
39
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
+∞
24.1
23
*
A98
ICPC
Health maint/preventive medicine
0.3
23.5
383
4782
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
26.0
23.3
32
13
C71.43
ICD-10 Finland
Malignant tumor of the occipital lobe grade IV glioma
+∞
23.1
22
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
22.7
124
433
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
17.7
22.5
35
21
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
22.1
147
590
9400/3-C71.2
ICD-O-3
Astrocytoma, NOS, of temporal lobe
+∞
22.0
21
*
C71.80
ICD-10 Finland
Overall malignant tumor of the brain without histology
+∞
22.0
21
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
21.0
20
*
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
+∞
21.0
20
*
G40.10
ICD-10 Finland
Simple partial seizures
31.4
20.7
27
9
N05CF01
ATC
zopiclone; oral
2.5
20.3
204
1043
9440/3-C71.0
ICD-O-3
Glioblastoma, NOS, of cerebrum
+∞
19.9
19
*
C71.03
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade IV glioma
+∞
19.9
19
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
109.0
19.7
21
*
N76
ICPC
Neoplasm nervous system unspecified
207.1
19.7
20
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
207.1
19.7
20
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
17.5
19.4
30
18
N03AG01
ATC
valproic acid; systemic, rectal
4.6
18.9
69
168
C71.9
ICD-10 Finland
Malignant neoplasm: Brain, unspecified
+∞
18.9
18
*
C71.31
ICD-10 Finland
Malignant tumor of the parietal lobe grand II glioma
+∞
18.9
18
*
WC105
NOMESCO Finland
Simple cytostatic therapy of local tumor recidive
+∞
18.9
18
*
B01AB10
ATC
tinzaparin; parenteral
6.3
18.8
51
88
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
21.8
18.8
27
13
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
17.8
17
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
185.7
17.6
18
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
29.9
17.5
23
8
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
9.1
17.2
36
42
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
14.7
17.0
28
20
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
16.7
16
*
R4110
NOMESCO Finland
Physiotherapy
2.5
16.3
158
775
G41.9
ICD-10 Finland
Status epilepticus, unspecified
25.4
16.1
22
9
WX704
NOMESCO Finland
Intubation
4.2
15.8
61
157
R4150
NOMESCO Finland
Neuropsychological rehabilitation
19.9
15.7
23
12
R4120
NOMESCO Finland
Occupational therapy
4.1
15.6
63
169
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
15.3
15.5
25
17
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
10.5
15.1
29
29
9440/3-C71.8
ICD-O-3
Glioblastoma, NOS, of overlapping lesion of brain
+∞
14.6
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.6
14
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.6
14.6
69
212
N03AF01
ATC
carbamazepine; oral, rectal
4.5
14.2
51
122
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
30.9
14.0
18
6
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
54.8
13.9
16
*
N03AX23
ATC
brivaracetam; systemic
77.1
13.6
15
*
C71.32
ICD-10 Finland
Malignant tumor of parietal lobe grade III glioma
+∞
13.6
13
*
H02AB09
ATC
hydrocortisone; systemic
8.2
13.2
29
37
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.9
13.2
43
93
183
Kela drug reimbursment
Lamotrigin and topiramate
15.5
13.2
21
14
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
10.9
12.9
24
23
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
12.7
209
1278
WX725
NOMESCO Finland
Noninvasive ventilation
5.2
12.6
39
80
9440/3-C71.4
ICD-O-3
Glioblastoma, NOS, of occipital lobe
+∞
12.5
12
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
12.5
12
*
C71.39
ICD-10 Finland
Malignant tumor of parietal lobe other or unspecified histology
+∞
12.5
12
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
12.5
12
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
132.9
12.5
13
*
N05BA04
ATC
oxazepam; oral
2.2
12.4
142
743
C71.4
ICD-10 Finland
Malignant neoplasm: Occipital lobe
+∞
11.5
11
*
JN4AD
NOMESCO Finland
Body CT examination
4.7
10.9
36
80
WX110
NOMESCO Finland
Local anesthesy
1.9
10.8
365
2831
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
13.2
10.7
18
14
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
61.2
10.7
12
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
112.1
10.5
11
*
C71.81
ICD-10 Finland
Overall malignant tumor of the brain grade II glioma
+∞
10.4
10
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
10.4
10
*
R4130
NOMESCO Finland
Speech therapy
6.1
10.2
27
46
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
10.2
104
510
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
11.7
9.6
17
15
D69.5
ICD-10 Finland
Secondary thrombocytopenia
101.7
9.4
10
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
9.4
9
*
C71
ICD-10 Finland
Malignant neoplasm of brain
+∞
9.4
9
*
TKC20
NOMESCO Finland
Catheterisation of bladder
3.1
9.3
50
170
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
9.1
60
231
XA400
NOMESCO Finland
EEG
15.9
9.1
14
9
B01AB05
ATC
enoxaparin; parenteral
2.0
9.0
143
840
R47.0
ICD-10 Finland
Dysphasia and aphasia
7.4
8.8
20
28
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.4
8.7
32
786
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
8.5
185
1211
G41.2
ICD-10 Finland
Complex partial status epilepticus
28.0
8.5
11
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
91.4
8.4
9
*
C71.02
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles grade III glioma
+∞
8.4
8
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
8.4
8
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
8.4
8
*
9400/3-C71.0
ICD-O-3
Astrocytoma, NOS, of cerebrum
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.6
8.3
36
105
L02BA01
ATC
tamoxifen; oral
33.9
8.1
10
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
8.0
47
170
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.4
7.9
38
838
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
7.8
228
2971
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
5.4
7.8
22
42
205
Kela drug reimbursment
Chronic hypertension
0.5
7.8
51
1004
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.4
7.6
25
643
R83
ICPC
Respiratory infection other
0.4
7.4
30
709
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
81.1
7.4
8
*
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
7.0
7.3
17
25
WX892
NOMESCO Finland
Monitored bed care
2.7
7.3
50
198
G81.9
ICD-10 Finland
Hemiplegia, unspecified
11.1
7.3
13
12
9400/3-C71.3
ICD-O-3
Astrocytoma, NOS, of parietal lobe
+∞
7.3
7
*
C71.0
ICD-10 Finland
Malignant neoplasm: Cerebrum, except lobes and ventricles
+∞
7.3
7
*
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
7.3
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
7.3
7
*
2151
FHL
Resection, big brain
+∞
7.3
7
*
C71.09
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles other or unspecified histology
+∞
7.3
7
*
G93.6
ICD-10 Finland
Cerebral oedema
30.4
7.2
9
*
C01DA14
ATC
isosorbide mononitrate; oral
0.3
7.2
15
475
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
11.1
6.8
12
11
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
22.8
6.7
9
*
A10BA02
ATC
metformin; oral
0.5
6.7
60
1076
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.4
6.6
38
790
G40
ICD-10 Finland
Epilepsy
8.8
6.6
13
15
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.4
6.6
39
802
M25.5
ICD-10 Finland
Pain in joint
0.5
6.5
52
965
SAA02
NOMESCO Finland
Basic examination of mouth
0.6
6.5
194
2561
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.3
6.4
16
467
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
70.6
6.4
7
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
6.4
82
439
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
6.4
61
290
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.4
6.4
29
89
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.9
6.3
19
40
1CD02
NOMESCO Finland
NA
+∞
6.3
6
*
AA003
NOMESCO Finland
Adjuvant radiotherapy of brain
+∞
6.3
6
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
6.3
6
*
C71.82
ICD-10 Finland
Overall malignant tumor of the brain grade III glioma
+∞
6.3
6
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
6.3
6
*
C71.91
ICD-10 Finland
Malignant tumor in unspecified location in the brain grade II glioma
+∞
6.3
6
*
C71.89
ICD-10 Finland
Overall malignant tumor of the brain other or unspecified histology
+∞
6.3
6
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
6.2
40
154
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.6
6.2
96
1480
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.5
6.1
50
926
F80.1
ICD-10 Finland
Expressive language disorder
12.7
6.1
10
8
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
8.7
6.1
12
14

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_GBM_ASTROCYTOMA_EXALLC – Brain glioblastoma and astrocytoma, excluding all cancers (controls excluding all cancers)

GWS hits: 2

This endpoint is excluded (different definition than used in FinnGen).