motor neuron disease: A disease involving the motor neuron.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
674 |
4. Check minimum number of eventsNone |
674 |
5. Include endpointsNone |
674 |
6. Filter based on genotype QC (FinnGen only) |
674 |
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G12
- Name in latin
- Morbus motoneuronalis
Similar endpoints
↥List of similar endpoints to
Motor neuron disease
based on the number of shared cases.
Similar with more cases:
- Motor neuron disease (with DMD)
- Systemic atrophies primarily affecting the central nervous system
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8362 | 3928 | 4249 |
| Only index persons | 4490 | 2114 | 2376 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.11 | 0.12 |
| Only index persons | 0.08 | 0.08 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 66.30 | 67.33 | 65.35 |
| Only index persons | 67.14 | 68.36 | 66.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 674 | 269 | 405 |
| Unadjusted period prevalence (%) | 0.14 | 0.09 | 0.18 |
| Median age at first event (years) | 67.64 | 67.35 | 67.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 603
- Matched controls
- 6029
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G12.2
ICD-10 Finland
Motor neuron disease
+∞
323.0
579
*
N07XX02
ATC
riluzole; oral
+∞
166.5
152
*
N99
ICPC
Neurological disease other
1665.9
140.3
131
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
67.8
130.7
149
29
R47.1
ICD-10 Finland
Dysarthria and anarthria
766.1
129.5
123
*
J96.1
ICD-10 Finland
Chronic respiratory failure
43.7
118.5
147
44
JDB10
NOMESCO Finland
Percutaneous gastrostomy
85.0
116.1
128
19
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
23.7
102.2
150
83
R13
ICD-10 Finland
Dysphagia
19.1
96.6
153
105
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
26.3
82.3
116
54
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
27.8
82.3
114
50
Z51.5
ICD-10 Finland
Palliative care
11.3
81.8
166
196
N28
ICPC
Limited function/disability (N)
131.3
75.9
80
7
TAB00
NOMESCO Finland
Lumbar puncture
51.0
66.8
80
18
R4130
NOMESCO Finland
Speech therapy
51.7
64.4
77
17
XG466
NOMESCO Finland
Sleep oxymetry
42.4
62.8
78
21
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
10.7
61.6
126
145
G47.3
ICD-10 Finland
Sleep apnoea
20.1
57.0
87
50
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
56.8
56.2
66
13
SPAT1229
SPAT
Assessment of need for aid
10.7
56.2
114
128
A28
ICPC
Limited function/disability NOS
6.0
54.5
171
373
L28
ICPC
Limited function/disability (L)
5.6
49.4
163
373
WX725
NOMESCO Finland
Noninvasive ventilation
11.6
48.3
93
93
R5140
NOMESCO Finland
Monitoring the use of the aid
14.4
47.9
83
66
G12.9
ICD-10 Finland
Spinal muscular atrophy, unspecified
+∞
46.4
44
*
AA1AD
NOMESCO Finland
CT of head and brain
5.6
41.8
135
296
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.8
41.0
157
415
N03AE01
ATC
clonazepam; systemic
16.0
40.0
66
46
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
412.7
39.5
39
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
109.7
38.2
41
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
12.0
38.0
71
66
R1260
NOMESCO Finland
Evaluation of communicative skills
37.2
35.5
45
13
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
7.5
34.0
84
127
N29
ICPC
Neurological sympt/complt other
53.3
33.9
40
8
R1250
NOMESCO Finland
Evaluation of functional capability
24.1
33.2
47
21
M03BX01
ATC
baclofen; systemic
57.7
32.6
38
7
N19
ICPC
Speech disorder
65.5
32.4
37
6
SPAT1216
SPAT
Assessment of functional ability
4.4
31.5
128
350
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
10.5
31.2
62
65
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
15.8
31.1
51
35
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
6.9
30.4
79
128
S06.0
ICD-10 Finland
Concussion
19.0
30.1
46
26
SPAT1231
SPAT
Assessment of adjustments needed in living environment
20.0
28.7
43
23
R5599
NOMESCO Finland
Other rehabilitation service
13.5
28.6
50
40
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
25.9
28.2
39
16
R4120
NOMESCO Finland
Occupational therapy
7.7
28.0
67
96
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
105.0
27.9
30
*
R4190
NOMESCO Finland
Nutritional therapy
11.3
27.8
53
51
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
31.8
27.5
36
12
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
7.3
26.6
66
100
G12.8
ICD-10 Finland
Other spinal muscular atrophies and related syndromes
+∞
26.2
25
*
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
17.5
26.2
41
25
N18
ICPC
Paralysis/weakness
42.1
26.1
32
8
D21
ICPC
Swallowing problem
24.7
25.0
35
15
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
36.2
24.5
31
9
G72.9
ICD-10 Finland
Myopathy, unspecified
249.2
23.8
24
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.8
23.5
110
337
SPAT1215
SPAT
Assessment of need for medical rehabilitation
9.3
23.3
49
57
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
+∞
23.1
22
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.6
23.0
113
359
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
8.6
22.4
49
61
N05AH04
ATC
quetiapine; oral
6.8
21.3
55
88
UDQ12
NOMESCO Finland
Flexible laryngoscopy
6.6
21.3
56
92
XA402
NOMESCO Finland
ENMG
15.8
20.4
33
22
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
13.7
20.4
35
27
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
33.8
20.3
26
8
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
33.8
20.3
26
8
SPAT1245
SPAT
Provision of support and information to patient’s family members
7.8
19.8
46
63
R25.3
ICD-10 Finland
Fasciculation
76.0
19.8
22
*
SPAT1234
SPAT
Support of social functional capacity
8.0
19.7
45
60
N06AX11
ATC
mirtazapine; oral
2.8
19.5
149
640
N05BA04
ATC
oxazepam; oral
3.0
19.4
128
501
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
19.3
189
935
G31.0
ICD-10 Finland
Circumscribed brain atrophy
+∞
18.8
18
*
XA800
NOMESCO Finland
Neuropsychological investigation
24.6
18.8
26
11
N06AB10
ATC
escitalopram; oral
3.7
18.8
87
262
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
9.6
18.6
38
42
G56.0
ICD-10 Finland
Carpal tunnel syndrome
10.6
18.6
36
36
N03AX12
ATC
gabapentin; oral
3.6
18.5
88
271
G12.1
ICD-10 Finland
Other inherited spinal muscular atrophy
+∞
17.8
17
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
17.8
17
*
XG416
NOMESCO Finland
Measurement of maximal airway pressure
+∞
17.8
17
*
Z50.5
ICD-10 Finland
Speech therapy
37.9
17.7
22
6
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
97.9
17.6
19
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
17.6
161
761
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
17.3
161
767
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.4
17.1
170
835
N06AB04
ATC
citalopram; systemic
3.3
17.1
94
322
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
+∞
16.7
16
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
11.2
16.6
31
29
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.8
16.6
56
125
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
9.2
16.4
34
39
SPAT1254
SPAT
Administration of medicine
3.1
16.0
93
330
3352A
ICD-9 Finland
Anterior horn cell disease, Motor neuron disease[SCLEROSIS LATERALIS AMYOTROPHICA]
+∞
15.7
15
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
15.7
15
*
NXL00
NOMESCO Finland
Biopsy of muscle
87.3
15.6
17
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
163.9
15.5
16
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
32.6
14.9
19
6
XX9TE
NOMESCO Finland
Compementary ultrasound examination
32.6
14.9
19
6
F80.1
ICD-10 Finland
Expressive language disorder
82.1
14.6
16
*
GX2D5
NOMESCO Finland
Sleep oximetry
153.4
14.5
15
*
A06AD11
ATC
lactulose; oral
2.8
14.5
98
386
T05
ICPC
Feeding problem of adult
27.9
14.3
19
7
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
14.3
74
243
N02AA01
ATC
morphine; systemic, rectal
7.5
14.2
33
46
ACC51
NOMESCO Finland
Release of median nerve
43.6
14.2
17
*
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
54.6
13.9
16
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
13.6
13
*
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
13.6
13
*
G20
ICD-10 Finland
Parkinson disease
142.9
13.5
14
*
N05AX08
ATC
risperidone; systemic
18.7
13.4
20
11
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
26.4
13.4
18
7
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
21.7
13.4
19
9
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
23.1
12.9
18
8
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
71.3
12.6
14
*
JDB01
NOMESCO Finland
Laparoscopic gastrostomy
71.3
12.6
14
*
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
12.5
12
*
N05BA06
ATC
lorazepam; systemic, sublingual
5.3
12.3
37
73
Z31.5
ICD-10 Finland
Genetic counselling
5.6
12.1
35
66
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
11.4
12.1
22
20
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
18.5
12.1
18
10
N03AG01
ATC
valproic acid; systemic, rectal
21.8
12.1
17
8
S01.0
ICD-10 Finland
Open wound of scalp
4.0
11.6
47
126
RS314
NOMESCO Finland
NA
+∞
11.5
11
*
UDQ42
NOMESCO Finland
Endoscopic assessment of swallowing function
122.1
11.5
12
*
M62.5
ICD-10 Finland
Muscle wasting and atrophy, not elsewhere classified
122.1
11.5
12
*
K90
ICPC
Stroke/cerebrovascular accident
122.1
11.5
12
*
RS340
NOMESCO Finland
NA
122.1
11.5
12
*
N05BA01
ATC
diazepam; systemic, rectal
3.0
11.4
67
240
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
10.8
11.3
21
20
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
25.5
11.2
15
6
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
20.5
11.2
16
8
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.9
11.1
45
121
G62.8
ICD-10 Finland
Other specified polyneuropathies
44.1
10.9
13
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
15.8
10.9
17
11
WX722
NOMESCO Finland
PEEP
7.4
10.8
25
35
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
21.9
10.7
15
7
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
14.5
10.5
17
12
N03AF01
ATC
carbamazepine; oral, rectal
7.0
10.5
25
37
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
10.4
10
*
RS310
NOMESCO Finland
NA
+∞
10.4
10
*
N07AA02
ATC
pyridostigmine; systemic
+∞
10.4
10
*
N05AN01
ATC
lithium; oral
+∞
10.4
10
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
+∞
10.4
10
*
XA421
NOMESCO Finland
Nocturnal polygraphy
+∞
10.4
10
*
N06AA09
ATC
amitriptyline; systemic
3.6
10.4
46
134
UJC01
NOMESCO Finland
Scopy of lower throat
10.8
10.3
19
18
R53
ICD-10 Finland
Malaise and fatigue
2.5
10.3
88
391
A98
ICPC
Health maint/preventive medicine
0.5
10.1
421
4901
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.3
9.8
48
152
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
13.6
9.7
16
12
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
4.3
9.6
35
86
R06.0
ICD-10 Finland
Dyspnoea
2.0
9.5
136
762
R47.0
ICD-10 Finland
Dysphasia and aphasia
101.5
9.4
10
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
17.9
9.4
14
8
N06DA02
ATC
donepezil; oral
17.9
9.4
14
8
A120_
NOMESCO Finland
NA
+∞
9.4
9
*
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
+∞
9.4
9
*
A210_
NOMESCO Finland
NA
+∞
9.4
9
*
SPAT1240
SPAT
Therapeutic discussion
4.0
9.4
36
93
J96.0
ICD-10 Finland
Acute respiratory failure
8.9
9.3
19
22
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.0
9.3
36
94
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
13.9
9.2
15
11
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
37.2
9.0
11
*
R49.08
ICD-10 Finland
Other specified dysphonia
7.6
9.0
20
27
N05AH03
ATC
olanzapine; systemic
18.9
9.0
13
7
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
12.8
8.9
15
12
R5110
SPAT
NA
5.8
8.8
24
43
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
14.3
8.7
14
10
RS122
NOMESCO Finland
NA
50.7
8.7
10
*
N87
ICPC
Parkinsonism
50.7
8.7
10
*
SPAT1262
SPAT
Handing over of treatment supplies
2.1
8.7
105
552
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
8.6
102
530
WYA20
NOMESCO Finland
Home visit
16.6
8.6
13
8
N06AX21
ATC
duloxetine; oral
3.8
8.6
35
96
3472A
ICD-9 Finland
Cataplexy and narcolepsy[OBSTRUKTIIVINEN UNIAPNEA]
+∞
8.3
8
*
K11.72
ICD-10 Finland
Xerostomia
+∞
8.3
8
*
Z93.1
ICD-10 Finland
Gastrostomy status
+∞
8.3
8
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
+∞
8.3
8
*
G35
ICD-10 Finland
Multiple sclerosis
+∞
8.3
8
*
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
8.3
8
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
8.3
8
*
N03AF02
ATC
oxcarbazepine; oral
+∞
8.3
8
*
N81
ICPC
Injury nervous system other
+∞
8.3
8
*
TNX05
NOMESCO Finland
Simple incision of soft tissue, unspecified region
+∞
8.3
8
*
L99
ICPC
Musculoskeletal disease other
8.7
8.3
17
20
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
8.3
88
436
M48.0
ICD-10 Finland
Spinal stenosis
2.5
8.3
66
284
XG410
NOMESCO Finland
Flow-volume spirometry
3.9
8.3
33
89
RS230
NOMESCO Finland
NA
22.3
8.0
11
5
F06.7
ICD-10 Finland
Mild cognitive disorder
22.3
8.0
11
5
U04
ICPC
Incontinence urine
4.0
8.0
30
77
W19
ICD-10 Finland
Unspecified fall
3.0
7.9
45
159
Z50.1
ICD-10 Finland
Other physical therapy
3.4
7.8
37
115
RS221
NOMESCO Finland
NA
9.6
7.8
15
16
R06.5
ICD-10 Finland
Mouth breathing
3.9
7.8
30
79
Z99.8
ICD-10 Finland
Dependence on other enabling machines and devices
45.5
7.7
9
*
WX723
NOMESCO Finland
CPAP therapy
45.5
7.7
9
*
RS311
NOMESCO Finland
NA
45.5
7.7
9
*
J96.9
ICD-10 Finland
Respiratory failure, unspecified
18.6
7.6
11
6
130
Kela drug reimbursment
Malignant tumour
0.2
7.6
10
404
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.9
7.5
23
48
N02AA05
ATC
oxycodone; systemic
2.1
7.5
92
484
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.7
7.5
31
87
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.5
7.3
15
18
G61.8
ICD-10 Finland
Other inflammatory polyneuropathies
+∞
7.3
7
*
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
7.3
7
*
A220_
NOMESCO Finland
NA
+∞
7.3
7
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
+∞
7.3
7
*
WX781
NOMESCO Finland
Remote monitoring, noninvasive ventilation
+∞
7.3
7
*
N05AX12
ATC
aripiprazole; systemic
+∞
7.3
7
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
+∞
7.3
7
*
34800
ICD-8 Finland
Motor neurone disease, Amyotrophic lateral sclerosis
+∞
7.3
7
*
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
7.3
7
*
G12.0
ICD-10 Finland
Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
+∞
7.3
7
*
G72.8
ICD-10 Finland
Other specified myopathies
+∞
7.3
7
*
R42
ICD-10 Finland
Dizziness and giddiness
2.0
7.3
93
499
SPAT1139
SPAT
Nutrition survey
4.7
7.3
23
50
SPAT1167
SPAT
Insertion of urinary catheter
3.9
7.1
28
75
Z73.6
ICD-10 Finland
Limitation of activities due to disability
12.2
7.1
12
10
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
40.5
6.8
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
6.7
223
1612
N05CF01
ATC
zopiclone; oral
1.7
6.7
154
1008
R41.0
ICD-10 Finland
Disorientation, unspecified
8.8
6.6
13
15
RK110
NOMESCO Finland
NA
10.2
6.6
12
12
L19
ICPC
Muscle symptom/complaint NOS
5.1
6.5
19
38
N03AX16
ATC
pregabalin; oral
1.9
6.5
96
540
JDB00
NOMESCO Finland
Gastrostomy
70.5
6.4
7
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
70.5
6.4
7
*
Z43.1
ICD-10 Finland
Attention to gastrostomy
70.5
6.4
7
*
F34.1
ICD-10 Finland
Dysthymia
70.5
6.4
7
*
N04BC05
ATC
pramipexole; oral
3.1
6.4
33
111
RS222
NOMESCO Finland
NA
8.3
6.4
13
16
N06AX16
ATC
venlafaxine; oral
3.2
6.3
31
101
Z75.5
ICD-10 Finland
Holiday relief care
18.2
6.3
9
5
RS313
NOMESCO Finland
NA
18.2
6.3
9
5
N86
ICPC
Multiple sclerosis
+∞
6.3
6
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
+∞
6.3
6
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
+∞
6.3
6
*
K91
ICPC
Cerebrovascular disease
+∞
6.3
6
*
N04BD01
ATC
selegiline; oral
+∞
6.3
6
*
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
+∞
6.3
6
*
WPA13
NOMESCO Finland
Palliative consultation
+∞
6.3
6
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
6.3
6
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
6.3
6
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
+∞
6.3
6
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
+∞
6.3
6
*
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
+∞
6.3
6
*
G45.4
ICD-10 Finland
Transient global amnesia
+∞
6.3
6
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
6.3
6
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
6.3
6
*
N06AX26
ATC
vortioxetine; oral
7.1
6.2
14
20
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
26.9
6.2
8
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
6.8
6.1
14
21
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
6.0
61
296
P29
ICPC
Psychological sympt/compl other
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
67
12
61.89
119.75
1.0
1.0
—
—
—
0
0
64
11
64.18
115.16
1.0
1.0
—
—
—
0
0
75
26
32.33
113.98
1.1
1.0
9.2
226.5
e6/l
0.47
61
18
74
26
31.85
111.94
1.2
1.0
724.1
164.1
e6/l
0.41
61
19
341
1092
5.30
101.88
2.5
1.7
246.9
195.5
u/l
1.01
325
1004
135
199
8.23
90.74
4.9
3.8
3.5
1.7
mmol/l
4.81
125
148
140
217
7.88
90.01
5.2
3.8
5.7
5.0
kpa
10.73
134
195
68
8
94.45
62.22
1.0
1.0
—
—
—
0
0
66
9
80.91
59.27
1.1
1.0
—
—
—
0
0
76
100
8.44
55.44
5.4
3.7
28.3
24.6
mmol/l
5.43
66
84
128
357
4.19
41.56
1.6
2.7
67.8
66.4
g/l
1.68
117
329
154
524
3.51
37.21
5.5
7.1
5.8
5.1
kpa
6.93
149
495
153
524
3.48
36.54
5.5
7.1
10.5
12.5
kpa
8.70
147
495
148
522
3.35
33.51
5.5
7.1
4.1
0.8
mmol/l
18.11
128
407
69
150
5.01
30.36
1.3
1.9
2.7
3.2
g/l
4.02
46
125
71
162
4.78
29.48
1.3
1.9
3.6
3.7
g/l
0.15
46
121
71
162
4.78
29.48
1.3
1.9
6.5
7.5
g/l
4.43
46
124
71
162
4.78
29.48
1.3
1.9
—
—
—
0
0
68
157
4.71
27.80
1.1
1.9
10.2
10.6
g/l
0.40
47
135
399
5187
0.43
23.49
3.6
4.8
2.8
2.7
mmol/l
0.98
335
4701
387
5069
0.44
22.57
3.4
4.2
4.8
4.6
mmol/l
1.48
325
4629
385
5027
0.45
21.48
3.5
4.2
1.5
1.5
mmol/l
0.41
325
4559
53
124
4.55
21.25
1.7
2.4
197.3
323.7
ug/l
0.88
47
116
377
4856
0.49
17.51
3.2
3.8
1.2
1.2
mmol/l
0.03
318
4365
48
123
4.12
17.10
1.3
1.7
0.0
0.0
g/l
0.50
43
111
155
778
2.29
16.68
1.7
1.7
1168.2
1165.3
nmol/l
0.01
123
571
49
131
3.96
16.48
1.1
1.6
40.0
37.2
g/l
2.56
43
114
46
121
4.01
15.82
1.1
1.7
0.0
0.0
g/l
0.00
41
109
50
141
3.75
15.60
1.4
2.0
0.2
1.7
g/l
1.81
43
119
37
83
4.66
15.59
2.6
2.5
18.4
15.8
%
3.72
27
45
368
4711
0.52
15.29
4.7
5.6
38.6
39.9
mmol/mol
2.26
325
4300
45
120
3.95
15.19
1.1
1.7
0.0
0.0
g/l
0.00
40
109
142
733
2.19
14.06
1.8
1.8
—
—
—
0
0
406
4986
0.53
13.50
3.9
4.4
5.9
6.0
mmol/l
0.67
360
4466
293
1982
1.85
13.21
3.5
4.8
35.5
34.9
g/l
1.00
276
1838
394
4830
0.56
11.97
14.0
12.6
91.9
75.6
ml/min/173m2
27.43
325
3885
494
5654
0.53
11.33
23.1
18.7
135.2
135.8
g/l
0.49
489
5538
494
5652
0.53
11.26
23.0
18.6
4.4
4.5
e12/l
1.52
478
5430
494
5649
0.53
11.15
23.0
18.6
244.9
240.9
e9/l
0.82
481
5444
33
89
3.85
10.98
2.4
2.1
141.6
128.9
g/l
2.21
28
61
316
2280
1.73
10.78
5.5
6.3
1.2
1.2
mmol/l
4.33
260
1938
125
685
2.01
10.35
2.4
3.3
0.8
0.8
mmol/l
0.35
106
635
474
5444
0.56
9.79
9.8
9.5
28.8
25.4
u/l
4.49
457
5189
284
2067
1.65
8.86
5.7
5.5
1.2
1.2
mmol/l
0.91
255
1855
10
10
10.14
8.66
1.0
1.0
—
—
—
0
0
380
4562
0.62
8.42
18.3
14.1
38.9
39.4
%
0.36
225
3149
95
515
1.98
8.02
1.9
1.6
—
—
—
0
0
346
2699
1.58
7.77
4.9
4.1
6.5
6.8
mmol/l
2.50
331
2521
99
1638
0.54
7.60
3.0
3.8
10.9
7.3
mg/mmol
0.43
53
1042
93
517
1.93
7.29
1.8
1.7
—
—
—
0
0
147
945
1.71
7.14
1.4
1.7
451.7
26873800.4
pmol/l
1.04
122
774
10
6
16.89
6.76
1.4
2.0
5.6
4.3
mmol/l
—
10
6
92
1481
0.56
6.22
2.5
3.3
0.8
0.9
ug/l
0.16
66
1029
76
427
1.88
5.76
3.4
3.4
4.8
1.7
mmol/l
6.67
61
319
40
183
2.26
5.27
1.6
2.0
—
—
—
0
0
51
261
2.03
5.07
6.7
9.7
27.2
24.6
mmol/l
6.83
44
244
250
1948
1.45
4.96
1.8
1.9
94.4
94.2
pmol/l
0.02
139
977
35
159
2.27
4.70
1.6
1.9
—
—
—
0
0
484
5315
0.68
4.53
18.8
15.0
3.9
4.0
mmol/l
7.44
472
5136
28
117
2.45
4.53
1.4
1.1
—
—
—
0
0
88
555
1.67
4.51
3.5
5.3
1.0
1.0
mmol/l
0.83
78
510
483
5302
0.69
4.46
19.0
14.8
139.7
139.7
mmol/l
0.07
475
5131
7
6
11.77
4.28
1.1
1.0
—
—
—
0
0
7
6
11.77
4.28
1.1
1.0
—
—
—
0
0
7
6
11.77
4.28
1.3
1.0
—
—
—
0
0
8
10
8.08
4.07
4.5
4.1
—
—
—
0
0
7
7
10.09
4.02
1.1
1.0
—
—
—
0
0
7
7
10.09
4.02
1.1
1.0
—
—
—
0
0
26
113
2.35
3.89
1.7
1.7
—
—
—
0
0
52
298
1.81
3.75
1.6
1.5
—
—
—
0
0
77
495
1.63
3.68
4.5
2.7
—
—
—
0
0
195
2422
0.73
3.47
3.8
5.5
6.6
3.8
ug/l
0.42
166
2178
64
399
1.67
3.45
7.3
7.3
1.1
1.3
mmol/l
1.81
59
390
177
1372
1.39
3.41
2.9
3.1
36.1
37.6
u/l
0.09
171
1301
156
2001
0.71
3.37
3.8
4.6
22.2
21.9
%
0.10
81
1089
7
11
6.42
3.19
1.0
1.1
—
—
—
0
0
19
79
2.45
3.16
1.1
1.1
—
—
—
0
0
49
294
1.72
3.06
1.7
1.5
—
—
—
0
0
10
31
3.26
2.78
1.1
1.1
—
—
—
0
0
190
2303
0.76
2.70
5.3
4.4
0.0
0.0
estimate
0.00
39
389
96
1293
0.70
2.69
2.9
2.6
11700.1
8976.0
umol/l
0.16
81
1120
37
609
0.58
2.63
2.8
4.9
15.8
44.8
ug/l
0.78
30
512
47
292
1.66
2.62
1.5
2.4
423.6
395.0
nmol/l
0.49
40
267
5
7
7.19
2.55
1.0
1.0
—
—
—
0
0
6
11
5.49
2.55
1.0
1.2
—
—
—
0
0
47
296
1.63
2.49
9.7
9.2
90.9
94.5
%
1.81
47
296
9
26
3.49
2.49
1.4
1.0
—
—
—
0
0
21
398
0.51
2.43
1.6
1.8
—
—
—
0
0
14
58
2.44
2.38
1.9
3.2
3.9
4.0
e9/l
0.12
14
58
8
22
3.67
2.37
2.1
4.5
—
—
—
0
0
182
1493
1.30
2.32
2.7
3.9
2.4
2.4
mmol/l
1.15
160
1280
204
1703
1.28
2.27
4.3
3.1
65.6
69.1
ng/l
0.06
183
1194
29
488
0.58
2.26
1.4
1.4
—
—
—
0
0
36
218
1.69
2.23
3.4
3.9
27.1
23.7
mmol/l
5.22
31
197
14
60
2.36
2.23
2.0
3.6
60.6
56.5
%
0.68
14
60
23
122
1.92
2.18
1.4
1.6
—
—
—
0
0
198
2334
0.79
2.16
3.9
3.1
0.0
0.0
estimate
0.00
39
383
6
14
4.31
2.15
1.3
1.7
—
—
—
0
0
9
30
3.03
2.15
1.8
1.2
—
—
—
0
0
9
30
3.03
2.15
1.8
1.2
—
—
—
0
0
194
2283
0.79
2.07
4.0
3.1
0.0
0.0
estimate
0.00
39
379
6
15
4.03
2.04
1.2
1.1
—
—
—
0
0
6
15
4.03
2.04
1.7
2.4
—
—
—
0
0
12
50
2.43
2.03
1.1
1.5
—
—
—
0
0
12
50
2.43
2.03
1.1
1.5
—
—
—
0
0
12
50
2.43
2.03
1.1
1.5
—
—
—
0
0
18
90
2.03
2.02
1.3
1.2
—
—
—
0
0
18
90
2.03
2.02
1.3
1.2
—
—
—
0
0
386
3510
1.23
1.95
3.9
3.7
10.8
13.5
mm/h
4.08
360
3194
17
85
2.03
1.91
1.7
1.5
—
—
—
0
0
46
309
1.52
1.91
2.7
3.4
75.9
95.2
ng/l
0.91
39
273
303
2698
1.22
1.84
6.6
8.9
4.1
4.1
e9/l
0.01
268
2281
8
29
2.78
1.79
1.1
1.7
—
—
—
0
0
8
29
2.78
1.79
1.1
1.7
—
—
—
0
0
8
29
2.78
1.79
1.1
1.7
—
—
—
0
0
8
29
2.78
1.79
1.1
1.7
—
—
—
0
0
48
333
1.48
1.73
1.4
1.4
1.5
1.4
%
0.23
41
283
8
30
2.69
1.73
1.0
1.2
—
—
—
0
0
21
118
1.80
1.72
1.5
1.6
—
—
—
0
0
5
13
3.87
1.72
1.2
2.3
61.3
56.8
ug/l
—
5
13
340
3077
1.21
1.71
5.3
3.9
52.0
1990.0
e6/l
—
7
40
11
49
2.27
1.64
1.0
1.0
—
—
—
0
0
11
49
2.27
1.64
2.3
1.9
89.0
89.8
%
0.17
11
49
5
125
0.40
1.51
1.6
3.3
14.4
357.5
u/ml
—
5
117
6
21
2.87
1.51
1.2
1.8
—
—
—
0
0
6
21
2.87
1.51
1.2
1.8
—
—
—
0
0
6
21
2.87
1.51
1.2
1.8
—
—
—
0
0
15
80
1.89
1.45
1.5
1.1
—
—
—
0
0
46
628
0.71
1.42
1.1
1.2
11.7
20.3
u/ml
0.53
17
230
26
165
1.60
1.42
1.9
2.8
—
—
—
0
0
37
255
1.48
1.41
1.4
1.3
—
—
—
0
0
10
46
2.19
1.40
1.2
1.9
—
—
—
0
0
16
89
1.82
1.38
1.5
1.5
—
—
—
0
0
5
17
2.95
1.36
1.2
3.2
—
—
—
0
0
5
18
2.79
1.28
1.0
1.2
—
—
—
0
0
9
44
2.06
1.27
3.4
2.3
—
—
—
0
0
9
44
2.06
1.27
1.2
1.9
—
—
—
0
0
14
77
1.84
1.26
1.9
1.4
—
—
—
0
0
219
2444
0.85
1.24
2.8
2.3
—
—
—
0
0
305
2790
1.17
1.24
3.3
2.6
39.9
52.4
u/l
3.17
285
2532
5
19
2.64
1.22
1.6
2.2
0.2
0.2
e9/l
—
5
19
26
379
0.67
1.18
1.7
1.9
11.9
12.6
nmol/l
0.18
21
335
13
72
1.82
1.15
1.8
1.4
—
—
—
0
0
14
80
1.77
1.13
1.1
1.2
—
—
—
0
0
16
96
1.68
1.11
1.0
1.1
—
14.3
—
0
6
12
66
1.83
1.09
1.9
1.4
—
—
—
0
0
124
1063
1.20
1.07
1.4
1.5
20.6
20.6
nmol/l
0.01
114
876
268
2456
1.15
1.02
5.0
6.7
11.5
12.5
umol/l
1.23
256
2321
33
439
0.74
0.92
2.8
2.3
29.3
48.5
u/l
1.11
26
381
8
43
1.87
0.87
1.4
1.4
—
—
—
0
0
6
115
0.52
0.83
1.0
1.7
—
—
—
0
0
6
32
1.88
0.82
2.5
1.4
—
—
—
0
0
0
26
0.00
0.78
0.0
5.8
—
71.6
—
0
5
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
88
757
1.19
0.76
1.2
1.2
0.7
1.3
u/ml
1.42
16
193
56
675
0.81
0.75
1.7
2.3
2.2
2.2
g/l
0.48
49
632
103
899
1.17
0.75
1.8
1.5
1.3
1.5
mg/l
0.39
85
700
160
1763
0.88
0.73
4.2
3.3
—
—
—
0
0
5
25
2.01
0.73
2.8
1.5
—
—
—
0
0
5
25
2.01
0.73
2.8
1.5
—
—
—
0
0
6
109
0.55
0.72
1.3
1.2
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
5
27
1.86
0.68
1.8
1.2
—
—
—
0
0
106
939
1.15
0.65
3.4
3.6
891.4
517.6
ng/l
0.19
92
799
190
1752
1.12
0.63
1.9
2.1
77.9
79.5
nmol/l
0.30
162
1533
44
363
1.23
0.60
2.5
3.3
1.2
1.2
mmol/l
0.92
35
317
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
6
35
1.72
0.58
1.2
1.2
—
—
—
0
0
8
54
1.49
0.57
1.9
1.5
—
—
—
0
0
476
4900
0.90
0.57
17.0
12.5
25.7
28.2
mg/l
0.73
412
3716
5
86
0.58
0.56
1.6
1.5
—
—
—
0
0
6
38
1.58
0.54
1.8
1.4
—
—
—
0
0
350
3363
1.08
0.48
3.3
3.3
15.2
15.0
pmol/l
1.15
326
2992
56
640
0.86
0.46
1.8
2.3
22.5
22.9
%
0.08
50
557
5
82
0.61
0.46
2.4
6.3
—
429.9
—
0
12
10
70
1.44
0.42
1.7
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
1.0
—
0
5
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
34
399
0.84
0.40
2.0
2.8
128.5
59.0
ml/min/173m2
0.71
11
151
69
620
1.13
0.38
7.8
6.1
—
—
—
0
0
9
66
1.37
0.38
1.2
1.3
—
—
—
0
0
5
36
1.39
0.38
1.0
1.5
—
100.0
—
0
6
105
1138
0.91
0.38
2.1
2.0
3.3
2.9
mg/l
0.74
85
962
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
93
854
1.10
0.36
3.0
3.5
2.5
2.5
mmol/l
0.45
78
745
73
663
1.11
0.35
1.2
1.2
39.1
46.3
iu/ml
0.11
19
203
7
52
1.35
0.31
2.6
1.4
—
—
—
0
0
169
1777
0.93
0.30
2.3
2.5
150.2
171.5
ug/l
0.79
154
1623
45
502
0.89
0.29
2.4
2.5
8.1
9.4
umol/l
0.25
40
445
130
1376
0.93
0.28
2.3
2.3
52.2
60.2
u/l
2.46
119
1242
10
76
1.32
0.28
1.1
1.8
14.3
27.9
ug/l
—
10
76
8
63
1.27
0.28
1.1
1.4
—
—
—
0
0
183
1750
1.06
0.27
3.7
3.2
—
—
—
0
0
12
150
0.80
0.27
1.5
4.0
—
1.1
—
0
10
77
830
0.92
0.27
2.9
3.0
1.7
1.7
e6/l
0.03
51
479
8
66
1.21
0.27
2.4
1.5
—
—
—
0
0
10
127
0.78
0.25
1.6
1.6
—
—
—
0
0
110
1162
0.94
0.24
2.0
2.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
171
1.17
0.23
2.9
2.5
0.4
0.3
u/ml
0.31
13
95
7
95
0.73
0.22
1.1
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
217
2239
0.95
0.21
3.2
4.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
283.0
—
0
7
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
68
725
0.93
0.19
1.9
2.3
13.5
12.6
umol/l
0.36
60
676
12
99
1.22
0.19
1.5
1.3
—
—
—
0
0
15
128
1.18
0.18
4.3
3.0
26.2
26.3
mg/l
—
9
78
7
58
1.21
0.18
1.0
1.0
—
—
—
0
0
7
59
1.19
0.18
2.9
4.5
—
—
—
0
0
24
214
1.13
0.17
1.0
1.2
95.6
166.2
iu/ml
—
6
75
10
119
0.84
0.15
1.1
1.4
—
—
—
0
0
16
181
0.88
0.14
2.2
1.5
—
—
—
0
0
426
4308
0.97
0.13
3.9
3.9
1.9
2.4
mu/l
0.85
391
3804
43
404
1.07
0.12
3.0
2.2
13.5
7.2
ug/l
0.37
38
363
14
158
0.88
0.12
2.4
1.5
—
—
—
0
0
48
506
0.94
0.11
1.4
1.3
—
—
—
0
0
10
115
0.87
0.10
2.5
1.6
—
—
—
0
0
116
1192
0.97
0.10
4.4
3.3
0.0
0.0
estimate
0.50
38
374
139
1357
1.03
0.10
3.5
3.2
0.6
0.6
e6/l
0.04
108
1014
84
868
0.96
0.09
2.7
2.8
1.3
1.0
e6/l
0.43
59
515
64
663
0.96
0.08
29.7
29.9
1.2
1.5
inr
—
10
83
5
63
0.79
0.08
1.0
1.4
—
106.8
—
0
10
17
184
0.92
0.07
1.2
1.0
—
—
—
0
0
13
119
1.09
0.06
1.5
1.4
—
—
—
0
0
376
3785
0.99
0.05
6.1
7.3
72.2
80.5
u/l
5.25
348
3505
12
110
1.09
0.05
2.2
1.5
—
—
—
0
0
148
1500
0.98
0.05
2.7
2.8
1093.1
1573.3
ng/l
0.92
121
1290
18
170
1.06
0.04
1.4
1.2
—
—
—
0
0
13
122
1.07
0.02
2.3
1.8
91.6
86.1
%
0.34
13
116
63
622
1.01
0.01
3.6
4.2
34.6
32.5
%
0.68
38
365
97
962
1.01
0.01
3.7
3.1
1.0
1.0
kg/l
0.81
22
131
11
104
1.06
0.01
1.5
1.5
52.5
40.8
nmol/l
0.69
11
99
13
134
0.97
0.00
3.3
2.1
3.4
3.6
g/l
0.19
13
127
12
121
0.99
0.00
1.4
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
36.9
—
0
6
0
5
0.00
0.00
0.0
1.6
—
30.1
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
12
120
1.00
0.00
1.4
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
8
86
0.93
0.00
1.4
1.3
—
—
—
0
0
7
70
1.00
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_ALS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ALS | 18.515 [14.27, 24.02] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.318 |
During the follow-up period (1.1.1998 — 31.12.2019), 2037 out of 2507 females with G6_ALS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ALS | 9.357 [7.48, 11.7] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.04 |
During the follow-up period (1.1.1998 — 31.12.2019), 1983 out of 2612 males with G6_ALS died.
Mortality risk
Mortality risk for people of age
years, who have G6_ALS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 1.608% | 1.809% |
| 5 | 9.35% | 11.766% |
| 10 | 22.668% | 26.493% |
| 15 | 41.38% | 44.597% |
| 20 | 62.462% | 65.032% |
Relationships between endpoints
↥Index endpoint: G6_ALS – Motor neuron disease
GWS hits: 9
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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