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Malignant neoplasm of oesophagus, excluding all cancers (controls excluding all cancers)

Endpoint Browser PheWeb

C3_OESOPHAGUS_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C15
  • Hospital discharge: ICD-9 — 150
  • Hospital discharge: ICD-8 — 150
  • Cause of death: ICD-10 — C15
  • Cause of death: ICD-9 — 150
  • Cause of death: ICD-8 — 150
  • Cancer registry: Topography ICD-O-3 — C15
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

1314

4. Check minimum number of events

None

1314

5. Include endpoints

None

1314

6. Filter based on genotype QC (FinnGen only)

1314

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Malignant neoplasm of oesophagus, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1314 297 1017
Unadjusted period prevalence (%) 0.37 0.10 0.45
Median age at first event (years) 68.65 68.93 68.57

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
782
Matched controls
7821
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
221.0
323.0
317
24
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
+∞
323.0
536
*
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
506
*
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
1568.4
323.0
295
*
A03FA01
ATC
metoclopramide; systemic, rectal
33.8
323.0
483
356
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
303.5
271
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
16.6
259.1
619
1456
A04AA02
ATC
granisetron; systemic, transdermal
1098.6
251.8
233
*
8070/3-C15.9
ICD-O-3
Squamous cell carcinoma, NOS, of esophagus, NOS
+∞
249.8
226
*
L01BC06
ATC
capecitabine; oral
+∞
231.0
210
*
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
+∞
219.4
200
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2755.3
210.2
194
*
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
+∞
200.9
184
*
JN4BD
NOMESCO Finland
Extensive body CT
23.9
195.2
292
190
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
188.3
173
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
77.8
185.5
207
36
Z51.5
ICD-10 Finland
Palliative care
35.0
180.0
237
96
N02AA05
ATC
oxycodone; systemic
13.0
179.4
364
492
WX302
NOMESCO Finland
Thoracal epidural anesthesy
55.1
173.1
205
50
8140/3-C15.9
ICD-O-3
Adenocarcinoma, NOS, of esophagus, NOS
+∞
156.6
145
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
122.5
148.5
157
16
R4190
NOMESCO Finland
Nutritional therapy
57.3
145.4
171
38
WF002
NOMESCO Finland
Radical radiotherapy
1612.4
142.2
134
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
187.3
136.4
139
9
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
134.3
125
*
A04AA01
ATC
ondansetron; systemic, rectal
36.0
127.8
166
58
R13
ICD-10 Finland
Dysphagia
12.7
117.1
225
241
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
115.5
108
*
8140/3-C15.5
ICD-O-3
Adenocarcinoma, NOS, of lower third of esophagus
+∞
114.4
107
*
WX600
NOMESCO Finland
Single shot through catheter
330.4
114.3
113
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
24.1
112.8
164
85
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
+∞
112.2
105
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
398.9
107.0
105
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.2
106.0
198
196
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
+∞
104.6
98
*
C15.1
ICD-10 Finland
Malignant neoplasm: Thoracic part of oesophagus
+∞
99.1
93
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
42.7
98.8
123
34
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
95.8
90
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
99.8
95.7
104
12
WF049
NOMESCO Finland
Radiotherapy of metastasis
1000.7
92.8
89
*
UJC12
NOMESCO Finland
Flexible oesophagoscopy
88.7
91.7
101
13
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
16.2
89.9
151
114
JCC10
NOMESCO Finland
Transthoracic partial oesophagectomy without interposition
+∞
88.2
83
*
K22.2
ICD-10 Finland
Oesophageal obstruction
66.4
86.3
99
17
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.1
85.7
347
1052
XX3DW
NOMESCO Finland
Time consuming IT work
12.6
85.3
161
158
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
83.9
79
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
875.3
82.0
79
*
C15.0
ICD-10 Finland
Malignant neoplasm: Cervical part of oesophagus
+∞
81.7
77
*
C15.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oesophagus
+∞
81.7
77
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
72.0
68
*
JN4AD
NOMESCO Finland
Body CT examination
12.3
70.4
133
128
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
66.6
63
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
27.3
66.4
92
38
JDB10
NOMESCO Finland
Percutaneous gastrostomy
42.2
64.3
80
21
WZC30
NOMESCO Finland
Teaching
6.5
60.4
174
332
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.4
60.3
262
796
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
74.2
60.3
68
10
A04AD12
ATC
aprepitant; systemic
+∞
57.0
54
*
A02BC02
ATC
pantoprazole; systemic
3.6
56.4
597
3680
WW500
NOMESCO Finland
Blood transfusion
18.0
54.9
87
54
JN4CD
NOMESCO Finland
Very extensive body CT
20.2
54.1
82
45
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.5
54.0
226
652
ZXE40
NOMESCO Finland
More than seven and less than nine hours
16.8
53.0
86
57
ZX090
NOMESCO Finland
Other technic of radiotherapy
147.6
52.5
55
*
D77
ICPC
Malignant digestive neopl other/NOS
+∞
51.6
49
*
8070/3-C15.5
ICD-O-3
Squamous cell carcinoma, NOS, of lower third of esophagus
+∞
50.6
48
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
49.5
47
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
49.5
47
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
48.4
46
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
48.4
46
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
46.3
44
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
46.3
44
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
474.1
45.7
45
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.6
45.6
145
306
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
45.2
43
*
WX402
NOMESCO Finland
General anaesthesia
4.6
44.3
173
456
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
66.6
43.7
50
8
ZX120
NOMESCO Finland
Intravenous
5.6
42.9
135
280
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
41.7
260
1016
B01AB05
ATC
enoxaparin; parenteral
3.1
41.3
300
1306
L03AA02
ATC
filgrastim; parenteral
151.4
41.2
43
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
32.1
41.0
54
18
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
41.0
39
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
39.9
38
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.8
39.9
106
176
UJD02
NOMESCO Finland
Gastroscopy
6.9
38.6
101
164
C16.00
ICD-10 Finland
Cardia
+∞
37.8
36
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
73.7
37.3
42
6
TPX10
NOMESCO Finland
Implantation of vascular injection port
13.6
36.4
64
51
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
99.7
35.0
38
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
34.6
33
*
8070/3-C15.4
ICD-O-3
Squamous cell carcinoma, NOS, of middle third of esophagus
+∞
34.6
33
*
K22.1
ICD-10 Finland
Ulcer of oesophagus
11.0
34.5
67
66
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.2
34.3
97
174
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
34.2
413
2376
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
12.9
34.0
61
51
C15.2
ICD-10 Finland
Malignant neoplasm: Abdominal part of oesophagus
+∞
33.6
32
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
340.7
33.1
33
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
15.5
30.9
51
35
A06AH03
ATC
naloxegol; oral
53.8
30.6
36
7
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
30.4
29
*
A79
ICPC
Malignancy NOS
+∞
30.4
29
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
313.9
30.0
30
*
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
+∞
29.3
28
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
28.3
27
*
1CD01
NOMESCO Finland
NA
+∞
28.3
27
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
26.8
124
371
R4110
NOMESCO Finland
Physiotherapy
2.6
26.6
249
1202
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.6
26.6
70
114
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
139.6
25.8
27
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.3
25.5
81
167
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
+∞
25.1
24
*
ZXE00
NOMESCO Finland
One hour or less
2.3
24.9
324
1842
JDB00
NOMESCO Finland
Gastrostomy
134.3
24.7
26
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
23.6
130
444
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
5.0
23.3
78
170
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
6.6
23.2
61
99
D84
ICPC
Oesophagus disease
55.8
23.2
27
5
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
31.1
22.9
30
10
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
9.9
22.8
46
49
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
23.8
22.7
32
14
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
123.6
22.7
24
*
WX872
NOMESCO Finland
Intensive care
4.1
22.5
92
245
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
22.1
200
933
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.7
22.1
78
180
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
+∞
22.0
21
*
8000/3-C15.9
ICD-O-3
Neoplasm, malignant of esophagus, NOS
+∞
22.0
21
*
WX002
NOMESCO Finland
Sedation and analgesia
2.5
21.8
198
924
RD210
NOMESCO Finland
NA
10.5
21.6
42
42
A02BC05
ATC
esomeprazole; systemic
2.1
21.5
340
2070
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
34.9
21.2
27
8
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
20.9
20
*
8140/3-C15.2
ICD-O-3
Adenocarcinoma, NOS, of abdominal esophagus
+∞
20.9
20
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
20.9
20
*
116
Kela drug reimbursment
Prostate cancer
+∞
20.9
20
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
20.9
20
*
K22.7
ICD-10 Finland
Barrett oesophagus
10.2
20.8
41
42
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
79.0
20.8
23
*
JFF00
NOMESCO Finland
Catheter enterostomy
79.0
20.8
23
*
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
36.8
19.9
25
7
TJF00
NOMESCO Finland
Insertion of jejunal tube
+∞
19.9
19
*
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
19.9
19
*
B01AB10
ATC
tinzaparin; parenteral
5.0
19.6
64
136
J01MA12
ATC
levofloxacin; systemic
2.4
19.2
185
884
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
56.5
19.0
22
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
56.5
19.0
22
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.2
19.0
46
67
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
11.4
18.9
35
32
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
18.8
18
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
194.4
18.6
19
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.5
18.6
67
158
A98
ICPC
Health maint/preventive medicine
0.5
18.3
485
6024
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
18.1
304
1861
ZXD05
NOMESCO Finland
Urgent procedure
2.1
18.0
269
1568
C15
ICD-10 Finland
Malignant neoplasm of oesophagus
+∞
17.8
17
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
17.8
17
*
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
64.8
16.8
19
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
16.7
16
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
16.7
16
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
16.7
16
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
6.0
15.9
44
77
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
15.7
15
*
PJD53
NOMESCO Finland
Block dissection of aortic lymph nodes
+∞
15.7
15
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
15.7
15
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
15.7
15
*
1505A
ICD-9 Finland
Malignant neoplasm of oesophagus, Lower third of oesophagus
+∞
15.7
15
*
JAH00
NOMESCO Finland
Laparotomy
6.5
15.0
39
63
A06AD11
ATC
lactulose; oral
2.3
14.8
151
734
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
14.6
14
*
RD160
NOMESCO Finland
NA
36.8
14.5
18
5
K92.0
ICD-10 Finland
Haematemesis
4.6
14.2
49
111
R11
ICD-10 Finland
Nausea and vomiting
3.2
14.0
75
250
SPAT1109
SPAT
Analgesia with portable analgesic pump
54.3
13.8
16
*
8070/3-C15.3
ICD-O-3
Squamous cell carcinoma, NOS, of upper third of esophagus
+∞
13.6
13
*
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
13.6
13
*
JCC30
NOMESCO Finland
Transthoracic partial oesophagectomy with interposition of intestine
+∞
13.6
13
*
Z3226
NOMESCO Finland
Physiotherapist
2.2
13.4
158
817
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
7.5
13.4
31
43
L03
ICPC
Low back symptom/complaint
0.3
13.3
34
985
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
4.0
13.3
53
139
GD1AD
NOMESCO Finland
Thorax CT examination
4.0
13.1
52
136
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
10.3
13.0
25
25
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.9
12.9
53
143
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
11.8
12.9
23
20
R50.9
ICD-10 Finland
Fever, unspecified
2.4
12.9
111
495
N02AA01
ATC
morphine; systemic, rectal
9.9
12.8
25
26
GBB00
NOMESCO Finland
Tracheostomy
9.9
12.8
25
26
T18.1
ICD-10 Finland
Foreign body in oesophagus
8.0
12.7
28
36
JFF01
NOMESCO Finland
Laparoscopic catheter enterostomy
+∞
12.5
12
*
8144/3-C15.9
ICD-O-3
Adenocarcinoma, intestinal type of esophagus, NOS
+∞
12.5
12
*
L02BB03
ATC
bicalutamide; oral
+∞
12.5
12
*
Z43.1
ICD-10 Finland
Attention to gastrostomy
+∞
12.5
12
*
JCF00
NOMESCO Finland
Insertion of prosthetic tube into oesphagus
+∞
12.5
12
*
D00.1
ICD-10 Finland
Carcinoma in situ: Oesophagus
+∞
12.5
12
*
WC125
NOMESCO Finland
Demanding cytostatic therapy of local tumor recidive
+∞
12.5
12
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
12.5
12
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
12.5
12
*
K22.3
ICD-10 Finland
Perforation of oesophagus
47.4
11.9
14
*
JCB00
NOMESCO Finland
Oesophagostomy
+∞
11.5
11
*
L01BC53
ATC
tegafur, combinations; systemic
+∞
11.5
11
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
11.5
11
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
11.5
11
*
GBA35
NOMESCO Finland
Endoscopic insertion of stent into trachea
+∞
11.5
11
*
C16.04
ICD-10 Finland
Malignant tumor of cardiac intestinal carcinoma
+∞
11.5
11
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
11.5
11
*
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
121.7
11.5
12
*
JCC00
NOMESCO Finland
Transhiatal partial oesophagectomy without interposition
121.7
11.5
12
*
UGB02
NOMESCO Finland
Tracheoscopy
121.7
11.5
12
*
C10AA07
ATC
rosuvastatin; oral
0.4
11.4
71
1435
JAH01
NOMESCO Finland
Laparoscopy
5.1
11.4
35
71
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
35.6
11.3
14
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
11.1
239
1537
N03AX16
ATC
pregabalin; oral
1.9
11.1
178
1036
R52.0
ICD-10 Finland
Acute pain
5.3
11.0
33
65
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
10.8
91
400
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
18.1
10.8
16
9
N02AX02
ATC
tramadol; systemic, rectal
1.7
10.5
318
2263
Z98.8
ICD-10 Finland
Other specified postsurgical states
7.9
10.4
23
30
8144/3-C15.5
ICD-O-3
Adenocarcinoma, intestinal type of lower third of esophagus
+∞
10.4
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.4
10
*
115
Kela drug reimbursment
Breast cancer
+∞
10.4
10
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
+∞
10.4
10
*
178
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
+∞
10.4
10
*
C16.03
ICD-10 Finland
Malignant tumor of cardiac diffuse carcinoma
+∞
10.4
10
*
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
+∞
10.4
10
*
8010/3-C15.9
ICD-O-3
Carcinoma, NOS, of esophagus, NOS
+∞
10.4
10
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.0
10.3
21
24
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
10.1
94
434
L02AE02
ATC
leuprorelin; implant, parenteral
40.6
10.0
12
*
D21
ICPC
Swallowing problem
6.8
10.0
24
36
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
5.2
9.9
30
60
AA1BD
NOMESCO Finland
Extensive CT of head and brain
5.3
9.9
29
56
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
9.8
255
1730
B01AB04
ATC
dalteparin; parenteral
3.4
9.8
46
140
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.5
9.8
45
135
Z2221
NOMESCO Finland
Medical doctor
1.8
9.6
193
1208
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
101.2
9.4
10
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
101.2
9.4
10
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
101.2
9.4
10
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.5
9.4
81
1483
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
9.4
9
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
9.4
9
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
9.4
9
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.2
9.4
20
25
N05BA06
ATC
lorazepam; systemic, sublingual
2.9
9.4
58
213
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.3
108
553
D70.82
ICD-10 Finland
Drug-induced neutropenia
15.8
9.1
14
9
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
9.0
96
474
N02AA03
ATC
hydromorphone; systemic, rectal
24.3
8.9
12
5
T05
ICPC
Feeding problem of adult
10.9
8.8
16
15
JCC96
NOMESCO Finland
Other partial oesophagectomy
+∞
8.3
8
*
JDD00
NOMESCO Finland
Total gastrectomy and Roux-en-Y oesophagojejunostomy
+∞
8.3
8
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
8.3
8
*
8144/3-C16.0
ICD-O-3
Adenocarcinoma, intestinal type of cardia, NOS
+∞
8.3
8
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
8.3
8
*
JN4DD
NOMESCO Finland
Scout CT scan of torso
+∞
8.3
8
*
K20
ICD-10 Finland
Oesophagitis
5.6
8.3
23
42
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.2
8.2
42
137
JN6AD
NOMESCO Finland
CT of torso and neck
14.7
8.2
13
9
WX704
NOMESCO Finland
Intubation
2.7
8.2
55
213
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.5
8.1
93
1572
L15
ICPC
Knee symptom/complaint
0.4
8.1
42
914
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.9
8.1
19
28
C10AA05
ATC
atorvastatin; oral
0.6
8.1
187
2651
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
22.3
8.0
11
5
A28
ICPC
Limited function/disability NOS
1.9
8.0
132
770
J86.9
ICD-10 Finland
Pyothorax without fistula
7.9
7.9
17
22
ZX100
NOMESCO Finland
Oral
7.9
7.9
17
22
R4130
NOMESCO Finland
Speech therapy
4.3
7.8
27
64
WX882
NOMESCO Finland
High dependency care
3.6
7.8
33
94
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
45.4
7.7
9
*
N05CF01
ATC
zopiclone; oral
1.6
7.6
246
1744
KA1FN
NOMESCO Finland
Isotope renography
18.6
7.6
11
6
NK6AN
NOMESCO Finland
Total body bone isotope imaging
25.3
7.6
10
*
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
25.3
7.6
10
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.7
7.6
24
52
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
7.5
143
875
M25.5
ICD-10 Finland
Pain in joint
0.5
7.5
61
1143
GBB13
NOMESCO Finland
Revision of tracheostomy
80.8
7.4
8
*
HAC20
NOMESCO Finland
Total mastectomy
80.8
7.4
8
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
80.8
7.4
8
*
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
+∞
7.3
7
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
7.3
7
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
7.3
7
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
+∞
7.3
7
*
1CD02
NOMESCO Finland
NA
+∞
7.3
7
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
7.3
7
*
FM1FN
NOMESCO Finland
Heart function isotope examination
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
1504A
ICD-9 Finland
Malignant neoplasm of oesophagus, Middle third of oesophagus
+∞
7.3
7
*
I50.1
ICD-10 Finland
Left ventricular failure
0.2
7.2
6
320
K22.0
ICD-10 Finland
Achalasia of cardia
20.2
7.1
10
5
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
6.7
7.1
17
26
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
6.4
7.0
17
27
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
6.9
57
248
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
4.9
6.9
21
44
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
0.5
6.7
62
1116
ZXB10
NOMESCO Finland
Medial
22.7
6.7
9
*
L17
ICPC
Foot/toe symptom/complaint
0.5
6.6
68
1188
N06DX01
ATC
memantine; oral
0.2
6.6
9
360
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
6.9
6.5
15
22
R01AD09
ATC
mometasone; nasal
0.6
6.5
131
1931
L02BG04
ATC
letrozole; oral
70.4
6.4
7
*
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
70.4
6.4
7
*
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
6.4
51
966
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.5
6.4
14
19
G47.3
ICD-10 Finland
Sleep apnoea
0.5
6.4
67
1164
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.2
6.3
31
100
I50.0
ICD-10 Finland
Congestive heart failure
0.3
6.3
18
499
GAA31
NOMESCO Finland
Thoracoscopy
18.2
6.3
9
5
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.6
6.3
103
1593
8480/3-C15.5
ICD-O-3
Mucinous adenocarcinoma of lower third of esophagus
+∞
6.3
6
*
8070/3-C15.0
ICD-O-3
Squamous cell carcinoma, NOS, of cervical esophagus
+∞
6.3
6
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
L01CB01
ATC
etoposide; systemic
+∞
6.3
6
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
6.3
6
*
8246/3-C15.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of esophagus, NOS
+∞
6.3
6
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.2
6.3
31
101
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
6.2
82
440
GDC00
NOMESCO Finland
Lobectomy of lung
26.9
6.2
8
*
UJC02
NOMESCO Finland
Rigid oesophagoscopy
7.1
6.2
14
20
J94.8
ICD-10 Finland
Other specified pleural conditions
5.1
6.2
18
36
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.8
6.2
16
28
UJC01
NOMESCO Finland
Scopy of lower throat
8.7
6.1
12
14
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.9
6.0
23
61

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_OESOPHAGUS_EXALLC – Malignant neoplasm of oesophagus, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).