Adenocarcinoma and papillary adenocarcinoma of stomach, excluding all cancers (controls excluding all cancers)

C3_STOMACH_ADENO_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C16
  • Cancer registry: Morphology ICD-O-3 8140|8145
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

1061

4. Check minimum number of events

None

1061

5. Include endpoints

None

1061

6. Filter based on genotype QC (FinnGen only)

1061

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Adenocarcinoma and papillary adenocarcinoma of stomach, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1061 305 756
Unadjusted period prevalence (%) 0.27 0.10 0.33
Median age at first event (years) 67.71 65.08 68.77

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
998
Matched controls
9980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
570
*
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
+∞
323.0
376
*
A03FA01
ATC
metoclopramide; systemic, rectal
24.7
323.0
562
495
H02AB02
ATC
dexamethasone; systemic
193.6
323.0
344
27
8140/3-C16.9
ICD-O-3
Adenocarcinoma, NOS, of stomach, NOS
+∞
306.5
278
*
L01BC06
ATC
capecitabine; oral
+∞
304.2
276
*
A04AA02
ATC
granisetron; systemic, transdermal
1844.5
292.6
270
*
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
+∞
279.7
255
*
JDD00
NOMESCO Finland
Total gastrectomy and Roux-en-Y oesophagojejunostomy
2890.4
256.6
237
*
107
Kela drug reimbursment
Pernicious anaemia
40.4
243.9
310
110
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
424.5
236.0
228
7
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
9.6
230.4
678
1798
8145/3-C16.9
ICD-O-3
Carcinoma, diffuse type of stomach, NOS
+∞
225.8
208
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2374.6
219.0
204
*
C16.00
ICD-10 Finland
Cardia
+∞
201.0
186
*
B03BA03
ATC
hydroxocobalamin; parenteral
13.8
197.6
374
414
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
+∞
170.8
159
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
163.1
152
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
39.5
155.8
198
62
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
+∞
150.9
141
*
C16.0
ICD-10 Finland
Malignant neoplasm: Cardia
+∞
148.7
139
*
JN4BD
NOMESCO Finland
Extensive body CT
16.4
146.0
247
196
C16.23
ICD-10 Finland
Malignant tumor of the corpus ventriculi diffuse carcinoma
+∞
138.8
130
*
Z51.5
ICD-10 Finland
Palliative care
23.0
138.5
205
111
C16.2
ICD-10 Finland
Malignant neoplasm: Body of stomach
+∞
129.0
121
*
A04AA01
ATC
ondansetron; systemic, rectal
33.8
125.2
165
58
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
121.4
114
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
120.3
113
*
C16.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of stomach
+∞
115.9
109
*
N02AA05
ATC
oxycodone; systemic
7.2
115.3
322
622
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
136.1
113.8
120
10
C16.20
ICD-10 Finland
Malignant tumor of the corpus ventriculi without histology
+∞
102.9
97
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
551.9
102.5
100
*
B81
ICPC
Anaemia vit B12/folate deficiency
11.4
102.0
203
219
R4190
NOMESCO Finland
Nutritional therapy
39.8
102.0
129
37
C16.03
ICD-10 Finland
Malignant tumor of cardiac diffuse carcinoma
+∞
93.2
88
*
C16.3
ICD-10 Finland
Malignant neoplasm: Pyloric antrum
+∞
90.0
85
*
C16.39
ICD-10 Finland
Malignant tumor of the antrum ventriculi other or unspecified carcinoma
+∞
90.0
85
*
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
243.8
88.0
89
*
C16.33
ICD-10 Finland
Malignant tumor of the antrum ventriculi diffuse carcinoma
+∞
86.7
82
*
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
+∞
84.6
80
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
13.3
83.6
152
133
C16.30
ICD-10 Finland
Malignant tumor of the antrum ventriculi without histology
+∞
83.5
79
*
C16.29
ICD-10 Finland
Malignant tumor of the corpus ventriculi other or unspecified carcinoma
+∞
82.4
78
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
78.1
74
*
JAH01
NOMESCO Finland
Laparoscopy
17.1
72.1
117
77
C16.4
ICD-10 Finland
Malignant neoplasm: Pylorus
+∞
70.7
67
*
L03AA02
ATC
filgrastim; parenteral
154.9
68.9
72
5
TPX10
NOMESCO Finland
Implantation of vascular injection port
16.5
68.1
112
76
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
26.5
67.3
94
39
JN4AD
NOMESCO Finland
Body CT examination
11.6
65.8
127
124
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
9.8
65.1
138
161
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.7
61.6
329
1160
JN4CD
NOMESCO Finland
Very extensive body CT
18.9
59.8
93
54
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.5
59.7
150
230
A04AD12
ATC
aprepitant; systemic
601.5
58.3
57
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
57.9
55
*
C16.04
ICD-10 Finland
Malignant tumor of cardiac intestinal carcinoma
+∞
57.9
55
*
8145/3-C16.2
ICD-O-3
Carcinoma, diffuse type of body of stomach
+∞
56.8
54
*
JAH00
NOMESCO Finland
Laparotomy
13.8
55.1
97
77
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
54.7
52
*
JDC20
NOMESCO Finland
Partial gastrectomy and Roux-en-Y reconstruction
193.7
53.5
55
*
B01AB05
ATC
enoxaparin; parenteral
3.2
53.5
364
1514
C61
ICD-10 Finland
Malignant neoplasm of prostate
148.1
53.4
56
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
9.8
52.6
110
124
C16.01
ICD-10 Finland
Malignant tumor in cardia early diffuse gastric carcinoma early diffuse gastric carcinoma
+∞
52.6
50
*
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
52.6
50
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
52.6
50
*
C16.34
ICD-10 Finland
Malignant tumor of the antrum ventriculi intestinal carcinoma
+∞
51.5
49
*
8145/3-C16.0
ICD-O-3
Carcinoma, diffuse type of cardia, NOS
+∞
51.5
49
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
49.4
47
*
WX600
NOMESCO Finland
Single shot through catheter
72.5
48.6
55
8
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
19.4
48.3
74
41
8140/3-C16.3
ICD-O-3
Adenocarcinoma, NOS, of gastric antrum
+∞
47.3
45
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
47.3
45
*
WZC30
NOMESCO Finland
Teaching
4.9
46.2
165
388
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
46.2
44
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
46.2
44
*
C16.24
ICD-10 Finland
Malignant tumor of the corpus ventriculi intestinal carcinoma
+∞
44.1
42
*
D74
ICPC
Malignant neoplasm stomach
+∞
44.1
42
*
8145/3-C16.3
ICD-O-3
Carcinoma, diffuse type of gastric antrum
+∞
43.0
41
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
12.0
42.8
80
72
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
48.7
42.3
51
11
178
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
+∞
40.9
39
*
C16.21
ICD-10 Finland
Malignant tumor of the corpus ventriculi early diffuse gastric carcinoma
+∞
40.9
39
*
A02BC02
ATC
pantoprazole; systemic
2.5
40.2
658
4368
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
42.9
39.7
49
12
UJD02
NOMESCO Finland
Gastroscopy
5.9
39.2
116
218
6322
FHL
Gastrectomy (including Roux-Y)
208.0
39.1
40
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
23.7
37.8
54
24
L01BC53
ATC
tegafur, combinations; systemic
+∞
37.7
36
*
C16
ICD-10 Finland
Malignant neoplasm of stomach
+∞
37.7
36
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
26.0
37.5
52
21
JDC10
NOMESCO Finland
Partial gastrectomy and gastrojejunostomy
380.8
37.3
37
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
37.8
37.2
47
13
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
104.1
37.0
40
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
36.7
35
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
370.0
36.2
36
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
191.8
36.0
37
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
34.9
260
1096
WX402
NOMESCO Finland
General anaesthesia
3.8
33.8
158
473
UJC12
NOMESCO Finland
Flexible oesophagoscopy
32.8
33.7
44
14
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
33.2
155
463
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
32.5
31
*
C16.5
ICD-10 Finland
Malignant neoplasm: Lesser curvature of stomach, unspecified
+∞
32.5
31
*
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
117.2
31.9
34
*
B01AB10
ATC
tinzaparin; parenteral
6.2
31.7
88
152
JKA20
NOMESCO Finland
Cholecystectomy
6.8
31.2
81
128
WW500
NOMESCO Finland
Blood transfusion
8.5
31.0
69
86
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
88.0
30.9
34
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.9
30.5
134
379
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
30.4
29
*
C16.31
ICD-10 Finland
Malignant tumor of the antrum ventriculi early diffuse gastric carcinoma
+∞
30.4
29
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
85.3
29.9
33
*
R11
ICD-10 Finland
Nausea and vomiting
3.9
29.4
130
369
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
6.6
29.4
78
127
116
Kela drug reimbursment
Prostate cancer
+∞
29.3
28
*
8140/3-C16.2
ICD-O-3
Adenocarcinoma, NOS, of body of stomach
+∞
28.3
27
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
28.3
27
*
ZX120
NOMESCO Finland
Intravenous
3.8
27.5
124
358
A06AH03
ATC
naloxegol; oral
55.0
27.3
32
6
JCC10
NOMESCO Finland
Transthoracic partial oesophagectomy without interposition
+∞
27.2
26
*
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
63.9
27.1
31
5
XX3DW
NOMESCO Finland
Time consuming IT work
5.3
26.7
84
169
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
12.5
26.7
48
40
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
26.2
239
1109
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
19.3
25.8
39
21
JMA10
NOMESCO Finland
Transabdominal total splenectomy
39.9
25.0
31
8
WF002
NOMESCO Finland
Radical radiotherapy
133.3
24.7
26
*
JDW97
NOMESCO Finland
Other laparoscopic operation on stomach or duodenum
+∞
24.0
23
*
JFF00
NOMESCO Finland
Catheter enterostomy
+∞
24.0
23
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
23.0
22
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
23.0
22
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
122.8
22.7
24
*
R18
ICD-10 Finland
Ascites
9.2
22.0
46
52
384
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
+∞
21.9
21
*
C16.02
ICD-10 Finland
Malignant tumor of cardiac early intestinal gastric carcinoma
+∞
21.9
21
*
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
31.9
21.6
28
9
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
12.8
21.0
37
30
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
20.9
20
*
A79
ICPC
Malignancy NOS
112.3
20.6
22
*
A98
ICPC
Health maint/preventive medicine
0.5
20.0
535
6838
C16.6
ICD-10 Finland
Malignant neoplasm: Greater curvature of stomach, unspecified
+∞
19.9
19
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
19.9
19
*
JDD96
NOMESCO Finland
Total gastrectomy with other reconstruction
+∞
19.9
19
*
115
Kela drug reimbursment
Breast cancer
+∞
19.9
19
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
19.7
159
681
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
101.9
18.6
20
*
JDE00
NOMESCO Finland
Gastrojejunostomy
193.4
18.6
19
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
9.1
18.3
38
43
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.1
18.2
105
365
K22.2
ICD-10 Finland
Oesophageal obstruction
10.3
18.0
35
35
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
17.8
17
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
17.8
17
*
376
Kela drug reimbursment
Cyanocobalamin
+∞
17.8
17
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.1
17.6
70
180
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
7.1
17.6
43
63
K92.0
ICD-10 Finland
Haematemesis
4.6
17.6
62
142
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
5.4
17.3
52
100
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
10.6
16.8
32
31
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
16.7
16
*
D00.2
ICD-10 Finland
Carcinoma in situ: Stomach
+∞
16.7
16
*
C16.19
ICD-10 Finland
Malignant tumor of the fundus ventriculi other or unspecified carcinoma
+∞
16.7
16
*
D77
ICPC
Malignant digestive neopl other/NOS
+∞
16.7
16
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
16.7
16
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
16.7
16
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
16.7
16
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
16.7
16
*
1514C
ICD-9 Finland
Malignant neoplasm of stomach, Body of stomach[MAHASYÖPÄ, CORPORIS DIFFUUSI KARSINOOMA]
+∞
16.7
16
*
JDC97
NOMESCO Finland
Laparoscopic partial gastrectomy with other reconstruction
+∞
16.7
16
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
16.7
402
2711
NK6AN
NOMESCO Finland
Total body bone isotope imaging
91.6
16.6
18
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
28.1
16.5
22
8
K92.1
ICD-10 Finland
Melaena
3.2
16.5
92
309
R13
ICD-10 Finland
Dysphagia
3.1
16.3
92
313
L02AE02
ATC
leuprorelin; implant, parenteral
34.0
15.8
20
6
JDC11
NOMESCO Finland
Laparoscopic partial gastrectomy and gastrojejunostomy
+∞
15.7
15
*
T91
ICPC
Vitamin/nutritional deficiency
11.5
15.3
28
25
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
15.3
69
199
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
14.6
14
*
C16.32
ICD-10 Finland
Malignant tumor of the antrum ventriculi early intestinal gastric carcinoma
+∞
14.6
14
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
14.6
14
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
81.3
14.6
16
*
A09AA02
ATC
multienzymes (lipase, protease etc.)
6.2
14.3
38
63
RD210
NOMESCO Finland
NA
9.0
14.0
29
33
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
13.8
185
997
B01AB04
ATC
dalteparin; parenteral
3.6
13.8
63
184
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.3
13.8
28
31
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
76.2
13.6
15
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
13.6
13
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
13.6
13
*
JFF01
NOMESCO Finland
Laparoscopic catheter enterostomy
+∞
13.6
13
*
C10AA05
ATC
atorvastatin; oral
0.5
13.5
180
2887
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
13.3
390
2739
TPX15
NOMESCO Finland
Removal of vascular injection port
22.9
12.9
18
8
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
7.6
12.7
29
39
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
12.6
143
717
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
12.5
144
725
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
12.5
12
*
C16.10
ICD-10 Finland
Malignant tumor of the fundus ventriculi without histology
+∞
12.5
12
*
C16.13
ICD-10 Finland
Malignant tumor of the fundus ventriculi diffuse carcinoma
+∞
12.5
12
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
12.5
12
*
C16.22
ICD-10 Finland
Malignant tumor of the corpus ventriculi early intestinal gastric carcinoma
+∞
12.5
12
*
C16.1
ICD-10 Finland
Malignant neoplasm: Fundus of stomach
+∞
12.5
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
12.4
117
539
N02AA01
ATC
morphine; systemic, rectal
8.1
12.4
27
34
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
12.3
132
643
K91.1
ICD-10 Finland
Postgastric surgery syndromes
38.0
12.2
15
*
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.9
12.0
29
43
J01MA12
ATC
levofloxacin; systemic
1.9
11.8
186
1064
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
65.7
11.6
13
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
65.7
11.6
13
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
11.6
278
1823
ZX121
NOMESCO Finland
Central venous catheter
23.2
11.6
16
7
8140/3-C16.4
ICD-O-3
Adenocarcinoma, NOS, of pylorus
+∞
11.5
11
*
C15.1
ICD-10 Finland
Malignant neoplasm: Thoracic part of oesophagus
+∞
11.5
11
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
11.5
11
*
Y77
ICPC
Malignant neoplasm prostate
+∞
11.5
11
*
C15.2
ICD-10 Finland
Malignant neoplasm: Abdominal part of oesophagus
+∞
11.5
11
*
I10
ICD-10 Finland
Essential (primary) hypertension
0.6
11.2
372
4849
Z31.5
ICD-10 Finland
Genetic counselling
5.2
11.0
33
65
R50.9
ICD-10 Finland
Fever, unspecified
2.1
10.9
129
660
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
12.1
10.9
19
16
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.4
10.8
43
1042
A02BC05
ATC
esomeprazole; systemic
1.6
10.6
341
2416
SPAT1053
SPAT
Memory test
0.4
10.6
53
1175
V03AF03
ATC
calcium folinate; systemic
60.6
10.6
12
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
7.1
10.6
25
36
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
14.4
10.5
17
12
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
111.1
10.4
11
*
6321
FHL
Subtotal gastrectomy (also includes oment and spleen removal)
+∞
10.4
10
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
10.4
10
*
L01BC04
ATC
carmofur; oral
+∞
10.4
10
*
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
10.4
10
*
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
32.9
10.3
13
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.7
10.2
28
50
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
40.5
10.0
12
*
N06DX01
ATC
memantine; oral
0.3
10.0
18
624
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
6.4
9.9
25
40
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
20.2
9.8
14
7
WX704
NOMESCO Finland
Intubation
2.7
9.8
65
247
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.1
9.8
37
93
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
6.6
9.8
24
37
JFC00
NOMESCO Finland
Entero-enterostomy
55.5
9.7
11
*
A02BC03
ATC
lansoprazole; oral
1.6
9.6
282
1944
WX002
NOMESCO Finland
Sedation and analgesia
1.8
9.5
166
979
I50.9
ICD-10 Finland
Heart failure, unspecified
0.5
9.4
84
1534
ZXC86
NOMESCO Finland
Use of endoscopic device
17.7
9.4
14
8
JCC00
NOMESCO Finland
Transhiatal partial oesophagectomy without interposition
+∞
9.4
9
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
9.4
9
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
9.4
9
*
JDH35
NOMESCO Finland
Endoscopic insertion of duodenal stent
+∞
9.4
9
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
9.4
9
*
15199
ICD-8 Finland
Malignant neoplasm of stomach, Part unspecified
+∞
9.4
9
*
PJD53
NOMESCO Finland
Block dissection of aortic lymph nodes
+∞
9.4
9
*
TJA10
NOMESCO Finland
Laparocentesis
+∞
9.4
9
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.3
9.4
45
139
A02BX02
ATC
sucralfate; oral
2.7
9.4
62
235
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
7.0
9.3
22
32
R4110
NOMESCO Finland
Physiotherapy
1.7
9.2
212
1362
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
9.2
68
276
P20
ICPC
Memory disturbance
0.4
8.9
44
983
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.7
8.8
37
103
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.3
8.8
80
361
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.3
8.8
15
533
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
8.8
125
687
N06DA02
ATC
donepezil; oral
0.2
8.7
12
483
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
8.7
67
280
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
50.4
8.7
10
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
8.3
8.6
18
22
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.8
8.6
27
57
JFB30
NOMESCO Finland
Right hemicolectomy
11.7
8.6
15
13
RD160
NOMESCO Finland
NA
27.8
8.5
11
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.0
8.5
46
156
HAC20
NOMESCO Finland
Total mastectomy
90.8
8.4
9
*
M01AH05
ATC
etoricoxib; oral
0.6
8.4
238
3270
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
8.3
8
*
8145/3-C16.4
ICD-O-3
Carcinoma, diffuse type of pylorus
+∞
8.3
8
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
8.3
8
*
WC125
NOMESCO Finland
Demanding cytostatic therapy of local tumor recidive
+∞
8.3
8
*
C16.14
ICD-10 Finland
Malignant tumor of the fundus ventriculi intestinal carcinoma
+∞
8.3
8
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
8.3
8
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
8.3
8
*
1CD02
NOMESCO Finland
NA
+∞
8.3
8
*
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
+∞
8.3
8
*
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
5.6
8.3
23
42
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.1
8.0
15
15
HAB40
NOMESCO Finland
Wedge excision of mammary gland
22.2
8.0
11
5
-50
ICPC
Medication/prescr/renewal
2.8
8.0
48
175
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.3
7.8
20
586
N40
ICD-10 Finland
Hyperplasia of prostate
0.6
7.8
142
2154
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.6
7.7
25
55
L02BA01
ATC
tamoxifen; oral
45.3
7.7
9
*
I50.0
ICD-10 Finland
Congestive heart failure
0.4
7.7
36
819
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
0.2
7.6
7
356
JFF10
NOMESCO Finland
Loop enterostomy
25.2
7.6
10
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
5.2
7.6
22
43
N05AX08
ATC
risperidone; systemic
0.4
7.6
24
641
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.7
7.5
24
52
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
0.6
7.4
98
1612
K56.7
ICD-10 Finland
Ileus, unspecified
4.3
7.4
26
62
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.6
7.4
155
2281
C09CA01
ATC
losartan; oral
0.6
7.3
96
1582
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
0.5
7.3
50
999
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
7.3
7
*
L02BB03
ATC
bicalutamide; oral
+∞
7.3
7
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
7.3
7
*
WB131
NOMESCO Finland
Very demanding neoadjuvant cytostatic therapy
+∞
7.3
7
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
7.3
7
*
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
+∞
7.3
7
*
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
+∞
7.3
7
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
7.3
7
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
7.3
7
*
C15.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oesophagus
+∞
7.3
7
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
7.3
7
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
+∞
7.3
7
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
7.3
7
*
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
0.5
7.3
52
1022
PJA10
NOMESCO Finland
Exploration of lymph nodes
15.9
7.2
11
7
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
30.2
7.2
9
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.6
7.1
167
2404
N05CF01
ATC
zopiclone; oral
1.5
7.1
306
2282
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.7
7.0
29
81
ZX112
NOMESCO Finland
Subcutaneous
7.0
7.0
16
23
C08CA01
ATC
amlodipine; oral
0.7
6.9
197
2723
KA1FN
NOMESCO Finland
Isotope renography
11.0
6.8
12
11
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
40.3
6.8
8
*
XF612
NOMESCO Finland
Measurement of central venous pressure
40.3
6.8
8
*
L02BG04
ATC
letrozole; oral
22.7
6.7
9
*
Z53.0
ICD-10 Finland
Procedure not carried out because of contraindication
22.7
6.7
9
*
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
12.3
6.6
11
9
6318
FHL
Resection (2/3) and gastrojejunostomy (including Roux-Y)
12.3
6.6
11
9
-55
ICPC
Local injection/infiltration
10.1
6.5
12
12
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.5
241
1733
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
70.3
6.4
7
*
C50.99
ICD-10 Finland
Breast, unspecified
70.3
6.4
7
*
ZX080
NOMESCO Finland
Image guided radiotherapy
70.3
6.4
7
*
WF001
NOMESCO Finland
Preoperative radiotherapy
70.3
6.4
7
*
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
70.3
6.4
7
*
A06AD11
ATC
lactulose; oral
1.6
6.4
172
1145
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.7
6.4
41
154
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
0.4
6.4
32
711
C78.5
ICD-10 Finland
Secondary malignant neoplasm of large intestine and rectum
+∞
6.3
6
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
6.3
6
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
6.3
6
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
6.3
6
*
C79.6
ICD-10 Finland
Secondary malignant neoplasm of ovary
+∞
6.3
6
*
WGA10
NOMESCO Finland
Measurement of pain intensity
+∞
6.3
6
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
6.3
6
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
6.3
6
*
1510E
ICD-9 Finland
Malignant neoplasm of stomach, Cardia[MAHASYÖPÄ,KARDIA,MUU TARK MÄÄR CA]
+∞
6.3
6
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
6.3
6
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
6.3
6
*
JD003
NOMESCO Finland
Adjuvant radiotherapy of gastric or duodenal tumor
+∞
6.3
6
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
6.3
6
*
JDC00
NOMESCO Finland
Partial gastrectomy and gastroduodenostomy
+∞
6.3
6
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
6.3
6
*
JDC96
NOMESCO Finland
Partial gastrectomy with other reconstruction
+∞
6.3
6
*
1505A
ICD-9 Finland
Malignant neoplasm of oesophagus, Lower third of oesophagus
+∞
6.3
6
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
+∞
6.3
6
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
26.8
6.2
8
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
6.3
6.2
15
24
N05BA06
ATC
lorazepam; systemic, sublingual
2.2
6.2
56
257
M05BX04
ATC
denosumab; parenteral
2.7
6.1
38
143
I50.1
ICD-10 Finland
Left ventricular failure
0.4
6.1
18
494
JWE00
NOMESCO Finland
Reoperation for deep haemorrhage in gastroenterological surgery
12.6
6.1
10
8
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
10.1
6.0
11
11
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
10.1
6.0
11
11
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.6
6.0
16
29
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.6
6.0
16
29
K83.0
ICD-10 Finland
Cholangitis
5.6
6.0
16
29

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_STOMACH_ADENO_EXALLC – Adenocarcinoma and papillary adenocarcinoma of stomach, excluding all cancers (controls excluding all cancers)

GWS hits: 3

This endpoint is excluded (different definition than used in FinnGen).