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Malignant neoplasm of tongue, excluding all cancers (controls excluding all cancers)

C3_TONGUE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

936

6. Filter based on genotype QC (FinnGen only)

936

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of tongue, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 936 361 575
Unadjusted period prevalence (%) 0.20 0.12 0.25
Median age at first event (years) 63.26 62.65 63.65

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
620
Matched controls
6199
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
189.0
323.0
353
43
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
305
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
323.0
394
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
293.9
246.8
237
13
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
+∞
243.2
217
*
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
678.1
239.7
222
5
JDB10
NOMESCO Finland
Percutaneous gastrostomy
256.1
211.0
206
12
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
+∞
202.5
183
*
8070/3-C02.9
ICD-O-3
Squamous cell carcinoma, NOS, of tongue, NOS
+∞
159.4
146
*
WF002
NOMESCO Finland
Radical radiotherapy
974.3
158.9
149
*
EJB40
NOMESCO Finland
Hemiglossectomy
+∞
157.1
144
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
154.8
142
*
GBB00
NOMESCO Finland
Tracheostomy
171.6
152.4
155
12
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
9.8
143.5
390
910
8070/3-C01.9
ICD-O-3
Squamous cell carcinoma, NOS, of base of tongue, NOS
+∞
140.0
129
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
138.9
128
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
133.2
123
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
27.5
130.0
183
93
N02AA05
ATC
oxycodone; systemic
12.5
126.4
255
328
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
81.0
125.3
139
22
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
171.7
121.2
124
9
A03FA01
ATC
metoclopramide; systemic, rectal
10.8
110.8
241
345
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
1244.9
109.9
104
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
44.9
104.8
129
36
H02AB02
ATC
dexamethasone; systemic
80.1
100.6
112
17
WX408
NOMESCO Finland
General anesthesy, balanced
6.5
92.5
314
846
A04AA02
ATC
granisetron; systemic, transdermal
1007.8
91.2
87
*
SAA03
NOMESCO Finland
Extended examination of mouth
5.8
90.9
397
1449
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
980.9
89.0
85
*
UJC01
NOMESCO Finland
Scopy of lower throat
136.4
88.7
93
8
PJA12
NOMESCO Finland
Sentinel node biopsy
954.2
86.8
83
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
480.8
86.3
84
*
C02.10
ICD-10 Finland
Malignant neoplasm of tip of tongue
+∞
85.4
80
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
129.6
84.4
89
8
XX3DW
NOMESCO Finland
Time consuming IT work
14.6
82.6
146
128
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
82.1
77
*
A07AA02
ATC
nystatin; oral
12.7
80.5
152
154
R4190
NOMESCO Finland
Nutritional therapy
28.1
76.9
106
45
EBA15
NOMESCO Finland
Extraction of large number of teeth
17.3
76.1
124
88
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
75.6
71
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
18.7
74.6
118
77
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
25.0
73.6
105
50
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
26.9
71.7
100
44
K13.29
ICD-10 Finland
Indefinite leukoplakia
43.8
70.5
87
23
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
135.4
68.5
72
6
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
68.0
64
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
12.1
65.2
125
127
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.9
64.7
183
356
C02.9
ICD-10 Finland
Malignant neoplasm: Tongue, unspecified
+∞
64.7
61
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
13.0
64.0
118
110
C02.2
ICD-10 Finland
Malignant neoplasm: Ventral surface of tongue
+∞
63.6
60
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
59.3
56
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.1
59.1
364
1603
WX402
NOMESCO Finland
General anaesthesia
6.0
58.0
182
399
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
162.6
56.9
59
*
EJB20
NOMESCO Finland
Excision of lesion of base of tongue
+∞
56.1
53
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
53.9
51
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
53.9
51
*
A04AA01
ATC
ondansetron; systemic, rectal
22.4
52.5
77
39
C02.1
ICD-10 Finland
Malignant neoplasm: Border of tongue
+∞
49.7
47
*
Z51.5
ICD-10 Finland
Palliative care
19.2
48.6
75
44
C02.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tongue
+∞
47.5
45
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
46.4
44
*
WZC30
NOMESCO Finland
Teaching
5.9
46.1
142
296
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
458.3
43.8
43
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
43.2
41
*
EBA10
NOMESCO Finland
Surgical removal of tooth
5.9
42.1
129
265
SXA10
NOMESCO Finland
Epithel biopsy of mouth
28.4
41.9
57
22
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
64.8
41.9
48
8
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
118.2
41.3
44
*
A04AD12
ATC
aprepitant; systemic
+∞
41.1
39
*
C02.0
ICD-10 Finland
Malignant neoplasm: Dorsal surface of tongue
+∞
41.1
39
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
41.1
39
*
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
423.8
40.6
40
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
94.6
40.3
44
5
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
40.0
38
*
K13.78
ICD-10 Finland
Other change in the oral mucosa
16.6
38.9
63
42
WX110
NOMESCO Finland
Local anesthesy
3.3
38.5
466
2980
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
49.5
38.4
46
10
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
37.9
36
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
8.8
37.6
84
109
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
389.6
37.4
37
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
202.0
37.2
38
*
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
36.8
35
*
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
+∞
35.8
34
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
10.3
35.1
71
77
UDQ12
NOMESCO Finland
Flexible laryngoscopy
6.9
34.7
91
150
SBB10
NOMESCO Finland
Teeth copy
7.5
34.3
85
129
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
+∞
33.6
32
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
33.6
32
*
D10.10
ICD-10 Finland
Benign tumor at the base of the tongue
+∞
32.6
31
*
D10.19
ICD-10 Finland
Benign tumor of the tongue UNS
65.4
32.4
37
6
K13.20
ICD-10 Finland
Idiopathic leukoplakia
50.4
31.9
38
8
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
31.5
30
*
R4110
NOMESCO Finland
Physiotherapy
3.2
31.5
211
868
R13
ICD-10 Finland
Dysphagia
6.0
31.1
91
173
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
31.0
333
1848
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
31.0
167
584
ZXE40
NOMESCO Finland
More than seven and less than nine hours
15.3
30.7
51
36
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
30.5
29
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
30.5
29
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
5.5
30.1
95
198
EBB10
NOMESCO Finland
Insertion of dental implant
18.3
29.7
46
27
EBB15
NOMESCO Finland
Insertion of dental implant abutment
29.6
29.2
39
14
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
84.3
29.0
32
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
7.9
28.6
67
93
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
57.9
28.4
33
6
A04AA55
ATC
palonosetron, combinations; systemic
+∞
28.3
27
*
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
5.5
27.7
86
175
ZXE20
NOMESCO Finland
More than three and less than five hours
4.0
27.5
123
364
SXC03
NOMESCO Finland
Other oral or dental procedure
17.7
27.5
43
26
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
+∞
27.3
26
*
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
+∞
27.3
26
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
43.5
27.0
33
8
K14.9
ICD-10 Finland
Disease of tongue, unspecified
78.8
27.0
30
*
EKA10
NOMESCO Finland
Biopsy of cheek
11.5
26.0
49
46
SAA04
NOMESCO Finland
Special inverstigation of mouth
5.6
25.9
79
157
A06AD11
ATC
lactulose; oral
3.5
25.7
134
449
ZXE30
NOMESCO Finland
More than five and less than seven hours
7.3
25.6
63
94
ECA20
NOMESCO Finland
Biopsy of gingiva
26.4
25.5
35
14
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.7
25.5
92
221
TJD20
NOMESCO Finland
Change of gastrostomy tube
60.7
25.2
29
5
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
25.2
24
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
73.0
25.0
28
*
SBA00
NOMESCO Finland
Microbiological examinations
11.0
25.0
48
47
K11.70
ICD-10 Finland
Hypoptyalism
94.0
24.8
27
*
ZXC10
NOMESCO Finland
Use of laser
11.7
24.8
46
42
ZZA00
NOMESCO Finland
Split skin graft
9.7
24.8
51
57
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
17.5
24.3
38
23
TPH07
NOMESCO Finland
Cathetrisation of artery
4.1
23.9
100
277
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
22.4
23.7
34
16
ZXE00
NOMESCO Finland
One hour or less
2.5
23.4
270
1483
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
4.4
23.2
90
232
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
23.1
22
*
D10.12
ICD-10 Finland
Bone tumor of the tip of the tongue
86.8
22.8
25
*
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
20.4
22.4
33
17
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.9
22.1
75
168
T05
ICPC
Feeding problem of adult
30.3
22.0
29
10
K10.26
ICD-10 Finland
Periostitis of jaw (acute)(chronic)(suppurative)
+∞
22.0
21
*
D20
ICPC
Mouth/tongue/lip symptom/complaint
6.6
21.9
58
96
WX002
NOMESCO Finland
Sedation and analgesia
2.8
21.9
165
706
SAA02
NOMESCO Finland
Basic examination of mouth
2.3
21.7
402
2751
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
7.2
21.6
53
79
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
21.3
252
1385
ED1AA
NOMESCO Finland
Mandipular X-ray examination
29.2
21.1
28
10
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
7.4
20.7
50
73
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
20.6
144
587
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
5.2
20.2
65
137
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.5
20.2
201
1003
Z3226
NOMESCO Finland
Physiotherapist
2.9
20.0
140
567
WW500
NOMESCO Finland
Blood transfusion
9.1
20.0
42
49
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
19.9
19
*
EJC99
NOMESCO Finland
Other reconstructive operations on tongue and floor of mouth
+∞
19.9
19
*
8070/3-C02.2
ICD-O-3
Squamous cell carcinoma, NOS, of ventral surface of tongue, NOS
+∞
19.9
19
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
19.9
19
*
116
Kela drug reimbursment
Prostate cancer
+∞
19.9
19
*
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
76.0
19.8
22
*
JN4BD
NOMESCO Finland
Extensive body CT
5.0
19.7
65
141
EBA00
NOMESCO Finland
Extraction of tooth
2.3
19.7
237
1298
EJB99
NOMESCO Finland
Other excision on tongue and floor of mouth
206.3
19.7
20
*
J02AC01
ATC
fluconazole; systemic
2.3
19.5
241
1338
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.1
19.4
41
48
A01AB09
ATC
miconazole; local oral
3.8
19.3
88
261
K05.31
ICD-10 Finland
Periodontitis pronounced
3.4
19.2
102
342
R4130
NOMESCO Finland
Speech therapy
8.2
19.1
43
56
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.6
19.1
68
160
B37.08
ICD-10 Finland
Other candidal stomatitis
35.6
19.0
24
7
K14.61
ICD-10 Finland
Glossodynia
28.9
18.9
25
9
C02.4
ICD-10 Finland
Malignant neoplasm: Lingual tonsil
+∞
18.8
18
*
EJW99
NOMESCO Finland
Other operation on tongue or floor of mouth
+∞
18.8
18
*
K13.22
ICD-10 Finland
Erythroplakia of oral epithelium, including tongue
103.2
18.7
20
*
4392
FHL
Tongue and / or Mouth resection or excision
195.6
18.6
19
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
18.6
253
1461
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.4
18.2
191
968
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.6
18.0
53
101
L03AA13
ATC
pegfilgrastim; parenteral
+∞
17.8
17
*
SXC05
NOMESCO Finland
Other oral or dental procedure
5.1
17.8
57
120
K05.30
ICD-10 Finland
Periodontitis complex
3.0
17.5
111
420
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
17.6
17.5
27
16
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
11.6
16.9
31
28
C04.0
ICD-10 Finland
Malignant neoplasm: Anterior floor of mouth
+∞
16.7
16
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
16.7
16
*
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
16.9
16.7
26
16
WX707
NOMESCO Finland
Fiberoscopic intubation
48.9
16.1
19
*
K08.3
ICD-10 Finland
Retained dental root
3.6
15.8
74
224
K02.1
ICD-10 Finland
Caries of dentine
2.0
15.8
344
2369
1412A
ICD-9 Finland
Malignant neoplasm of tongue, Tip and lateral border of tongue
+∞
15.7
15
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
15.7
15
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
19.8
15.7
23
12
GD1AD
NOMESCO Finland
Thorax CT examination
5.0
15.2
49
104
ECB20
NOMESCO Finland
Oral alveoplasty
14.4
15.1
25
18
JN6AD
NOMESCO Finland
CT of torso and neck
58.1
14.8
17
*
SPD05
NOMESCO Finland
Demanding fitting of total teeth prosthesis
58.1
14.8
17
*
C04.9
ICD-10 Finland
Malignant neoplasm: Floor of mouth, unspecified
+∞
14.6
14
*
4707
FHL
Dissection Colli radicalis
+∞
14.6
14
*
L03AA02
ATC
filgrastim; parenteral
153.4
14.5
15
*
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
17.5
14.4
22
13
D83
ICPC
Mouth/tongue/lip disease
27.9
14.3
19
7
K12.10
ICD-10 Finland
Stomatitis NOS
43.6
14.2
17
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
11.3
14.1
26
24
N02BE01
ATC
paracetamol; systemic, rectal
2.3
14.0
521
4336
SPF30
NOMESCO Finland
Soling for prothesis
7.4
14.0
33
47
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.4
14.0
69
218
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
6.7
13.9
35
55
Z2221
NOMESCO Finland
Medical doctor
2.2
13.9
170
914
TPX10
NOMESCO Finland
Implantation of vascular injection port
10.8
13.8
26
25
ZXA05
NOMESCO Finland
Left side
2.2
13.6
175
957
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
13.6
13
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
13.6
13
*
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
26.4
13.4
18
7
Z2446
NOMESCO Finland
Social worker
4.0
13.4
55
149
JN4AD
NOMESCO Finland
Body CT examination
4.9
13.2
43
93
EKB00
NOMESCO Finland
Excision of lesion of cheek
29.1
13.0
17
6
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
51.1
12.9
15
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.0
12.8
52
140
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
12.7
136
683
SPF20
NOMESCO Finland
Temporary soling for filling
15.8
12.7
20
13
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.1
12.7
50
131
D77
ICPC
Malignant digestive neopl other/NOS
+∞
12.5
12
*
115
Kela drug reimbursment
Breast cancer
+∞
12.5
12
*
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
+∞
12.5
12
*
EJB50
NOMESCO Finland
Total glossectomy
+∞
12.5
12
*
C02.3
ICD-10 Finland
Malignant neoplasm: Anterior two-thirds of tongue, part unspecified
+∞
12.5
12
*
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
20.5
12.5
18
9
D37.09
ICD-10 Finland
Lip, oral cavity and pharynx
132.6
12.5
13
*
Z43.1
ICD-10 Finland
Attention to gastrostomy
132.6
12.5
13
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
132.6
12.5
13
*
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
132.6
12.5
13
*
A01AB04
ATC
amphotericin B; local oral
4.3
12.4
46
114
ZX120
NOMESCO Finland
Intravenous
3.4
12.2
61
195
EB1WA
NOMESCO Finland
NA
21.8
12.1
17
8
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
11.7
190
1134
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
19.4
11.6
17
9
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
11.5
11
*
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
+∞
11.5
11
*
EJB70
NOMESCO Finland
Extensive partial excision of floor of mouth and tongue
+∞
11.5
11
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
122.2
11.5
12
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
11.5
410
3199
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
8.6
11.4
24
29
SCA03
NOMESCO Finland
Preventive oral health care, extensive
4.7
11.3
38
85
ECA30
NOMESCO Finland
Excision of lesion of gingiva
10.8
11.3
21
20
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
35.7
11.3
14
*
ZXC96
NOMESCO Finland
Robot assisted procedure
17.4
11.2
17
10
J01DB01
ATC
cefalexin; oral
1.9
11.1
484
4015
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
9.5
11.1
22
24
Z50.5
ICD-10 Finland
Speech therapy
10.3
11.1
21
21
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
5.7
11.0
31
57
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
12.2
10.9
19
16
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
5.4
10.9
32
62
PJA10
NOMESCO Finland
Exploration of lymph nodes
28.6
10.8
14
5
N02AX02
ATC
tramadol; systemic, rectal
1.8
10.7
264
1811
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
21.9
10.7
15
7
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.9
10.7
219
1412
SDA02
NOMESCO Finland
Parodonthologic therapy
1.9
10.7
200
1249
B01AB10
ATC
tinzaparin; parenteral
4.2
10.6
40
101
UJC02
NOMESCO Finland
Rigid oesophagoscopy
14.5
10.5
17
12
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
14.5
10.5
17
12
EJC30
NOMESCO Finland
Reconstruction of tongue
111.8
10.4
11
*
C04.1
ICD-10 Finland
Malignant neoplasm: Lateral floor of mouth
+∞
10.4
10
*
EJB60
NOMESCO Finland
Partial excision of floor of mouth
+∞
10.4
10
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
13.4
10.2
17
13
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
10.1
60
217
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.7
10.0
72
291
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
10.0
45
133
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
6.9
10.0
24
36
H03AA01
ATC
levothyroxine sodium; systemic
2.0
10.0
145
822
Z3231
NOMESCO Finland
Registered nurse
2.0
9.8
152
882
UDQ22
NOMESCO Finland
Microlaryngoscopy
13.6
9.7
16
12
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
9.7
154
902
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.7
9.6
41
116
L43.8
ICD-10 Finland
Other lichen planus
5.7
9.4
26
47
A79
ICPC
Malignancy NOS
101.5
9.4
10
*
GBB13
NOMESCO Finland
Revision of tracheostomy
101.5
9.4
10
*
UJC12
NOMESCO Finland
Flexible oesophagoscopy
17.9
9.4
14
8
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.9
9.4
151
887
ZXE90
NOMESCO Finland
More than 22 hours
12.6
9.4
16
13
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
9.4
9
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
9.4
9
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
9.4
9
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
+∞
9.4
9
*
QA7S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in jaw or lips
+∞
9.4
9
*
1410A
ICD-9 Finland
Malignant neoplasm of tongue, Base of tongue
+∞
9.4
9
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
9.4
9
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
9.4
9
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
8085/3-C01.9
ICD-O-3
Squamous cell carcinoma, HPV positive of base of tongue, NOS
+∞
9.4
9
*
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
+∞
9.4
9
*
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
22.1
9.4
13
6
XQ902
NOMESCO Finland
Other photography
22.1
9.4
13
6
ZXB10
NOMESCO Finland
Medial
22.1
9.4
13
6
TQW99
NOMESCO Finland
Other minor procedure on skin
4.5
9.3
32
74
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.8
9.3
30
65
L43.9
ICD-10 Finland
Lichen planus, unspecified
6.2
9.3
24
40
ZZR00
NOMESCO Finland
Flap of skin
13.9
9.2
15
11
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.8
9.2
38
105
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
6.4
9.2
23
37
L02AE02
ATC
leuprorelin; implant, parenteral
15.9
9.1
14
9
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.9
9.1
56
207
K14.69
ICD-10 Finland
Tongue pain UNS
37.3
9.0
11
*
K10.25
ICD-10 Finland
Sequences of jawbones
37.3
9.0
11
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
9.0
67
277
EMB10
NOMESCO Finland
Tonsillectomy
3.9
9.0
36
97
ZXA00
NOMESCO Finland
Right side
1.8
8.8
169
1056
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.8
8.7
21
32
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
50.7
8.7
10
*
K10.21
ICD-10 Finland
Osteoradionecrosis of jaw (acute)(chronic)(suppurative)
50.7
8.7
10
*
S01.50
ICD-10 Finland
Open wound in oral cavity
11.8
8.6
15
13
SPA02
NOMESCO Finland
Preparation for dental prosthetics
5.5
8.5
24
45
K13.21
ICD-10 Finland
Leukoplakia caused by tobacco
27.9
8.5
11
*
R07.0
ICD-10 Finland
Pain in throat
3.3
8.5
41
129
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
20.4
8.5
12
6
EJ2S1
NOMESCO Finland
Photography of oral mucosa
91.2
8.4
9
*
EWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of teeth, jaws, mouth and pharynx
91.2
8.4
9
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
91.2
8.4
9
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
8.4
56
216
4394
FHL
Glossectomy or hemiglossectomy
+∞
8.3
8
*
EEB00
NOMESCO Finland
Partial excision of maxilla
+∞
8.3
8
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
8.3
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.3
8
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
+∞
8.3
8
*
B01AB05
ATC
enoxaparin; parenteral
1.8
8.2
167
1060
K10.20
ICD-10 Finland
Osteomyelitis (neonatal) of jaw (acute)(chronic)(suppurative)
33.8
8.1
10
*
DHB00
NOMESCO Finland
Excision of lesion of external nose
33.8
8.1
10
*
K13
ICD-10 Finland
Other diseases of lip and oral mucosa
33.8
8.1
10
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
33.8
8.1
10
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.4
8.1
23
44
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
8.0
36
108
ZXD05
NOMESCO Finland
Urgent procedure
1.7
7.9
185
1223
EHA10
NOMESCO Finland
Biopsy of palate
13.2
7.9
13
10
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
5.5
7.9
22
41
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
7.8
54
216
K14.88
ICD-10 Finland
Other diseases of tongue
45.6
7.7
9
*
L02BA01
ATC
tamoxifen; oral
45.6
7.7
9
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
7.6
69
316
A06AH03
ATC
naloxegol; oral
18.6
7.6
11
6
RD210
NOMESCO Finland
NA
6.3
7.6
19
31
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
25.4
7.6
10
*
K13.2
ICD-10 Finland
Leukoplakia and other disturbances of oral epithelium, including tongue
25.4
7.6
10
*
JDB00
NOMESCO Finland
Gastrostomy
25.4
7.6
10
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.5
7.6
34
102
EDA10
NOMESCO Finland
Biopsy of mandible
81.0
7.4
8
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
7.8
7.4
16
21
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
7.8
7.4
16
21
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.7
7.4
31
88
N05CF01
ATC
zopiclone; oral
1.7
7.4
188
1268
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.0
7.4
28
73
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.0
7.4
28
73
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.0
7.3
22
45
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
7.3
7
*
9680/3-C01.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of base of tongue, NOS
+∞
7.3
7
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
7.3
7
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
7.3
7
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
8071/3-C02.1
ICD-O-3
Squamous cell carcinoma, keratinizing, NOS, of border of tongue
+∞
7.3
7
*
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
+∞
7.3
7
*
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
+∞
7.3
7
*
8070/3-C06.0
ICD-O-3
Squamous cell carcinoma, NOS, of cheeck mucosa
+∞
7.3
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.3
7
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
7.3
7
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
7.3
7
*
SPD00
NOMESCO Finland
Fitting and preparation of total teeth prosthesis
6.4
7.3
18
29
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.2
7.3
72
346
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.5
7.2
56
237
JDB01
NOMESCO Finland
Laparoscopic gastrostomy
30.4
7.2
9
*
SCB02
NOMESCO Finland
Training for mouth care at home
30.4
7.2
9
*
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
30.4
7.2
9
*
RS316
NOMESCO Finland
NA
20.3
7.1
10
5
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
4.6
7.1
23
51
A02BC05
ATC
esomeprazole; systemic
1.6
7.1
231
1664
A02BC02
ATC
pantoprazole; systemic
1.6
7.1
375
3050
WX730
NOMESCO Finland
Conventional respirator
5.6
7.0
19
35
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
14.0
6.9
11
8
R02AD02
ATC
lidocaine; local oral
5.4
6.8
19
36
N02AA01
ATC
morphine; systemic, rectal
9.5
6.8
13
14
GD6AD
NOMESCO Finland
CT of chest and neck
40.5
6.8
8
*
DWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in surgery of ear, nose and larynx
40.5
6.8
8
*
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
40.5
6.8
8
*
TJD10
NOMESCO Finland
Insertion of other tube into stomach or duodenum
40.5
6.8
8
*
K14.09
ICD-10 Finland
Glossit UNS
22.8
6.7
9
*
EDC38
NOMESCO Finland
Open reduction and fixation of fracture of body of mandible
22.8
6.7
9
*
ECA35
NOMESCO Finland
Complicated excision of lesion of gingiva
22.8
6.7
9
*
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
12.4
6.6
11
9
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
12.4
6.6
11
9
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
8.8
6.6
13
15
A01AB10
ATC
natamycin; local oral
3.9
6.5
25
66
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
6.5
103
597
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
7.5
6.4
14
19
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
70.5
6.4
7
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
5.0
6.4
19
39
SPF10
NOMESCO Finland
Demanding repatation of teeth prosthesis
4.3
6.4
22
53
SPD01
NOMESCO Finland
Mucosa-supported complete denture
8.3
6.4
13
16
J01FF01
ATC
clindamycin; systemic
1.7
6.3
158
1053
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
9.4
6.3
12
13
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
6.3
127
794
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
6.3
6
*
L02BB03
ATC
bicalutamide; oral
+∞
6.3
6
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
C10.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oropharynx
+∞
6.3
6
*
UJC20
NOMESCO Finland
Extensive endoscopy to identify diagnosed or suspected primary malignant neoplasm of head or neck
+∞
6.3
6
*
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
Z92.3
ICD-10 Finland
Personal history of irradiation
+∞
6.3
6
*
C02
ICD-10 Finland
Malignant neoplasm of other and unspecified parts of tongue
+∞
6.3
6
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
6.3
6
*
C09.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tonsil
+∞
6.3
6
*
C44.91
ICD-10 Finland
Unspecified localization of basocellular carcinoma of the skin
+∞
6.3
6
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
+∞
6.3
6
*
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
+∞
6.3
6
*
C06.9
ICD-10 Finland
Malignant neoplasm: Mouth, unspecified
+∞
6.3
6
*
JN4DR
NOMESCO Finland
Whole body metabolic PET with CT
+∞
6.3
6
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
6.3
6
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
6.3
6
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
27.0
6.2
8
*
XF612
NOMESCO Finland
Measurement of central venous pressure
27.0
6.2
8
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
6.2
58
272
K02.9
ICD-10 Finland
Dental caries, unspecified
5.4
6.2
17
32
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.6
6.2
26
75

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_TONGUE_EXALLC – Malignant neoplasm of tongue, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).