No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- C81-C96
- Name in latin
- Leuc(h)aemia myeloides
Similar endpoints
↥List of similar endpoints to
Myeloid leukaemia
based on the number of shared cases.
Similar with more cases:
- Myeloid leukaemia
- Primary_lymphoid and hematopoietic malignant neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
- Malignant neoplasm
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 922 | 405 | 517 |
| Unadjusted period prevalence (%) | 0.19 | 0.14 | 0.23 |
| Median age at first event (years) | 63.95 | 58.58 | 68.16 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 912
- Matched controls
- 9120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XW000
NOMESCO Finland
Bone marrow biopsy
137.4
323.0
518
86
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
911.5
323.0
696
32
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
323.0
304
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
323.0
567
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
300.0
271
*
WW500
NOMESCO Finland
Blood transfusion
49.6
219.6
266
75
189
Kela drug reimbursment
Imatinib
+∞
200.6
185
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
51.7
189.1
227
58
L03AA02
ATC
filgrastim; parenteral
1055.3
181.8
172
*
L01XE01
ATC
[U] imatinib; oral
+∞
171.4
159
*
A04AA01
ATC
ondansetron; systemic, rectal
47.2
168.5
206
56
127
Kela drug reimbursment
Transplant complication
53.8
137.7
164
37
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
+∞
133.7
125
*
M04AA01
ATC
allopurinol; systemic
7.6
130.4
362
727
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
297.2
128.7
128
5
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
700.2
126.6
122
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
119.4
112
*
L01XX05
ATC
hydroxycarbamide; oral
60.5
119.2
139
27
A05AA02
ATC
ursodeoxycholic acid; oral
46.3
118.3
145
37
R50.9
ICD-10 Finland
Fever, unspecified
7.3
110.2
306
592
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.9
103.3
297
596
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.5
99.1
263
467
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
+∞
97.7
92
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
12.1
96.0
185
188
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
92.3
87
*
316
Kela drug reimbursment
Imatinib
+∞
86.9
82
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.0
86.1
174
192
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
88.3
86.0
95
12
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
83.6
79
*
J05AB11
ATC
valaciclovir; oral
6.0
81.2
256
557
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
80.4
76
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
+∞
79.3
75
*
H02AB02
ATC
dexamethasone; systemic
34.4
73.6
96
31
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
268.0
73.5
74
*
J01MA12
ATC
levofloxacin; systemic
4.6
72.2
306
909
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
13.4
70.3
127
109
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
70.1
530
2578
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
51.3
70.0
84
18
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
68.6
65
*
ZX120
NOMESCO Finland
Intravenous
7.3
67.9
176
288
Z51.5
ICD-10 Finland
Palliative care
16.6
66.5
109
74
JN4BD
NOMESCO Finland
Extensive body CT
8.3
64.7
153
217
L01BB02
ATC
mercaptopurine; oral
45.4
64.4
79
19
152
Kela drug reimbursment
Nilotinib
+∞
64.3
61
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
8.6
64.2
148
201
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
61.1
58
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
60.1
57
*
D64.9
ICD-10 Finland
Anaemia, unspecified
5.2
59.0
207
491
J02AC03
ATC
voriconazole; systemic
317.0
59.0
59
*
WW200
NOMESCO Finland
Immunization
13.9
56.8
100
80
D70.89
ICD-10 Finland
Neutropenic splenomegaly
35.9
56.7
73
22
ZX112
NOMESCO Finland
Subcutaneous
46.6
56.6
69
16
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
27.9
56.1
77
30
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
55.8
53
*
L04AD01
ATC
ciclosporin; systemic
19.3
55.8
86
49
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
39.1
54.7
69
19
N02AA05
ATC
oxycodone; systemic
4.8
54.5
204
515
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
53.7
51
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
53.7
51
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
194.8
53.6
55
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.7
52.9
203
525
A04AA02
ATC
granisetron; systemic, transdermal
+∞
52.6
50
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
51.5
49
*
150
Kela drug reimbursment
Dasatinib
+∞
51.5
49
*
A41.9
ICD-10 Finland
Sepsis, unspecified
9.1
50.6
111
137
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
18.3
50.4
79
47
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
7.7
50.3
123
181
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
+∞
49.4
47
*
L01XX28
ATC
[D] imatinib; oral
+∞
48.4
46
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
48.4
46
*
L01XE06
ATC
[U] dasatinib; systemic
+∞
46.2
44
*
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
48.6
45.6
55
12
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
103.4
45.2
49
5
JN4AD
NOMESCO Finland
Body CT examination
9.4
44.8
96
113
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
44.4
230
771
L01XE08
ATC
[U] nilotinib; oral
+∞
43.1
41
*
212
Kela drug reimbursment
Gout
11.9
42.1
79
72
ZX090
NOMESCO Finland
Other technic of radiotherapy
153.9
42.1
44
*
115
Kela drug reimbursment
Breast cancer
+∞
42.0
40
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
13.5
42.0
74
59
TPX10
NOMESCO Finland
Implantation of vascular injection port
13.4
40.1
71
57
J01MA14
ATC
moxifloxacin; systemic
4.5
39.0
150
380
B73
ICPC
Leukaemia
+∞
37.8
36
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
382.2
37.3
37
*
L04AA06
ATC
mycophenolic acid; systemic
14.4
35.8
61
45
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
35.6
34
*
C92.5
ICD-10 Finland
Acute myelomonocytic leukaemia
+∞
35.6
34
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
35.3
317
1513
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
34.6
33
*
130
Kela drug reimbursment
Malignant tumour
+∞
34.6
33
*
TGC00
NOMESCO Finland
Bronchial lavation
9.4
34.2
72
82
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.5
33.6
91
153
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
+∞
33.5
32
*
328
Kela drug reimbursment
Nilotinib
+∞
33.5
32
*
J05AB01
ATC
aciclovir; systemic
2.9
32.8
244
1032
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
50.8
32.7
39
8
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
56.5
32.5
38
7
L01EA03
ATC
nilotinib; oral
+∞
32.5
31
*
116
Kela drug reimbursment
Prostate cancer
+∞
32.5
31
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
64.1
32.3
37
6
PJA12
NOMESCO Finland
Sentinel node biopsy
327.9
32.1
32
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
32.0
334
1714
H02AB09
ATC
hydrocortisone; systemic
11.8
31.7
59
53
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
323.4
31.0
31
*
L04AA01
ATC
[U] ciclosporin; systemic
12.4
30.8
56
48
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
30.7
129
352
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
21.4
30.7
45
22
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.4
30.6
118
297
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.6
30.1
72
101
J02AC04
ATC
posaconazole; systemic
160.2
29.8
31
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
160.2
29.8
31
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.9
29.8
77
121
J02AC01
ATC
fluconazole; systemic
2.3
29.1
360
1994
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
106.8
28.8
31
*
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
30.4
28.7
38
13
324
Kela drug reimbursment
Dasatinib
+∞
28.3
27
*
WW409
NOMESCO Finland
Other aferesis
149.5
27.8
29
*
1DB06
NOMESCO Finland
NA
+∞
27.2
26
*
2050A
ICD-9 Finland
Myeloid leukaemia, Acute
+∞
26.2
25
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
25.6
277
1415
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
25.1
24
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
24.6
135
454
D70.82
ICD-10 Finland
Drug-induced neutropenia
30.1
24.2
32
11
WF002
NOMESCO Finland
Radical radiotherapy
57.7
24.1
28
5
HAC20
NOMESCO Finland
Total mastectomy
+∞
24.1
23
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
24.1
23
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
24.1
23
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
24.1
23
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
24.1
23
*
L03AB05
ATC
interferon alfa-2b; parenteral
69.4
23.9
27
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
23.7
250
1252
A07AA02
ATC
nystatin; oral
4.3
23.6
91
228
H02AB04
ATC
methylprednisolone; systemic
2.7
23.3
182
775
ZXD05
NOMESCO Finland
Urgent procedure
2.2
23.1
319
1811
ZX121
NOMESCO Finland
Central venous catheter
235.6
22.7
23
*
2AX04
NOMESCO Finland
NA
123.1
22.7
24
*
L02BA01
ATC
tamoxifen; oral
123.1
22.7
24
*
L02AE02
ATC
leuprorelin; implant, parenteral
22.0
22.2
32
15
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
22.2
218
1049
H02AB06
ATC
prednisolone; systemic
2.0
22.2
445
2938
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
22.0
21
*
L01EA02
ATC
dasatinib; oral
+∞
22.0
21
*
1BC07
NOMESCO Finland
NA
+∞
22.0
21
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
22.0
21
*
C92.2
ICD-10 Finland
Atypical chronic myeloid leukaemia, BCR/ABL- negative
+∞
22.0
21
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
39.7
21.8
27
7
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
17.1
21.1
33
20
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
20.9
20
*
9873/3-C42.1
ICD-O-3
Acute myeloid leukemia without maturation of bone marrow
+∞
20.9
20
*
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
112.6
20.6
22
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
112.6
20.6
22
*
A40.8
ICD-10 Finland
Other streptococcal sepsis
17.8
20.1
31
18
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
19.9
19
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
19.9
19
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
19.9
19
*
B03XA02
ATC
darbepoetin alfa; parenteral
8.9
19.8
42
49
JN4CD
NOMESCO Finland
Very extensive body CT
10.1
19.8
39
40
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
12.5
19.7
35
29
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
204.2
19.6
20
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
41.0
19.6
24
6
NK6AN
NOMESCO Finland
Total body bone isotope imaging
47.1
19.3
23
5
A41.8
ICD-10 Finland
Other specified sepsis
8.1
19.2
43
55
TPH00
NOMESCO Finland
Phlebotomy
18.7
19.2
29
16
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.3
19.0
51
85
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.1
19.0
109
379
9860/3-C42.1
ICD-O-3
Myeloid leukemia, NOS, of bone marrow
+∞
18.8
18
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
18.8
18
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
71.4
18.8
21
*
L02BG04
ATC
letrozole; oral
18.0
18.3
28
16
ZX108
NOMESCO Finland
Inhalation
18.0
18.3
28
16
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
45.0
18.3
22
5
HA1AA
NOMESCO Finland
X-ray mammography
6.4
18.3
48
78
A02BC02
ATC
pantoprazole; systemic
1.9
18.0
561
4211
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
17.8
17
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
17.8
17
*
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
17.8
17
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
7.0
17.7
44
66
TAB00
NOMESCO Finland
Lumbar puncture
4.4
17.7
66
160
C03CA01
ATC
furosemide; systemic
2.0
17.7
316
1947
9983/3-C42.1
ICD-O-3
Myelodysplastic syndrome with excess blasts of bone marrow
183.4
17.6
18
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
17.4
17.5
27
16
Z2446
NOMESCO Finland
Social worker
3.5
17.4
83
251
GD1AD
NOMESCO Finland
Thorax CT examination
4.9
17.1
56
119
Z3231
NOMESCO Finland
Registered nurse
2.0
17.0
252
1441
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
16.9
95
325
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.4
16.8
62
149
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
16.7
93
313
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
16.7
16
*
9920/3-C42.1
ICD-O-3
Therapy-related myeloid neoplasm of bone marrow
+∞
16.7
16
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
16.7
16
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
16.7
16
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
16.7
16
*
L02BB03
ATC
bicalutamide; oral
+∞
16.7
16
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.3
16.7
87
282
5BA08
NOMESCO Finland
NA
20.5
16.5
24
12
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
16.4
196
1020
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
48.4
16.1
19
*
JN6AD
NOMESCO Finland
CT of torso and neck
21.4
16.0
23
11
B03XA01
ATC
erythropoietin; parenteral
12.5
15.9
28
23
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
11.5
15.8
29
26
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
15.7
15
*
170
Kela drug reimbursment
Bosutinib
+∞
15.7
15
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
15.7
15
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
15.7
15
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
15.7
15
*
D46.3
ICD-10 Finland
Refractory anemia with excess of blasts with transformation
162.6
15.5
16
*
SPAT1088
SPAT
Blood transfusion
29.2
15.2
20
7
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.4
15.2
55
130
B99
ICD-10 Finland
Other and unspecified infectious diseases
6.3
15.1
40
66
B01AB05
ATC
enoxaparin; parenteral
1.9
15.1
254
1510
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.1
15.0
31
35
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
14.7
347
2318
ZXE00
NOMESCO Finland
One hour or less
1.8
14.7
348
2330
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
14.6
14
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
14.6
14
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
14.6
14
*
9866/3-C42.1
ICD-O-3
Acute promyelocytic leukemia, t(15;17)(q22;q11-12) of bone marrow
+∞
14.6
14
*
Y77
ICPC
Malignant neoplasm prostate
81.4
14.6
16
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
152.3
14.5
15
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
54.2
13.8
16
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
54.2
13.8
16
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
24.2
13.8
19
8
R4110
NOMESCO Finland
Physiotherapy
1.9
13.8
228
1342
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
+∞
13.6
13
*
9895/3-C42.1
ICD-O-3
Acute myeloid leukemia with myelodysplasia-related changes of bone marrow
+∞
13.6
13
*
1DB07
NOMESCO Finland
NA
+∞
13.6
13
*
B01AB10
ATC
tinzaparin; parenteral
3.9
13.5
55
146
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.2
13.5
41
81
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
142.0
13.5
14
*
D64.8
ICD-10 Finland
Other specified anaemias
7.9
13.4
30
39
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
13.3
93
366
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
10.2
13.0
25
25
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
22.9
12.9
18
8
J01MA02
ATC
ciprofloxacin; systemic
1.7
12.7
349
2415
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.6
12.6
58
171
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
32.5
12.6
16
5
UJF32
NOMESCO Finland
Coloscopy
1.9
12.6
214
1266
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
12.5
12
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
12.5
12
*
C92.3
ICD-10 Finland
Myeloid sarcoma
+∞
12.5
12
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
12.5
12
*
L03AA04
ATC
NA
131.7
12.5
13
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
131.7
12.5
13
*
D45
ICD-10 Finland
Polycythaemia vera
9.1
12.3
25
28
Z2221
NOMESCO Finland
Medical doctor
1.8
12.2
239
1487
N02AX02
ATC
tramadol; systemic, rectal
1.7
12.0
357
2517
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
12.0
255
1626
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.8
11.9
77
289
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.0
11.7
37
77
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.1
11.7
66
226
WA010
NOMESCO Finland
Adjuvant whole body radiotherapy
+∞
11.5
11
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
11.5
11
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
11.5
11
*
A04AD12
ATC
aprepitant; systemic
+∞
11.5
11
*
9874/3-C42.1
ICD-O-3
Acute myeloid leukemia with maturation of bone marrow
+∞
11.5
11
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
11.5
11
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
11.5
11
*
L01XE14
ATC
[U] bosutinib; oral
+∞
11.5
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
121.5
11.4
12
*
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
11.3
57
182
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
25.4
11.2
15
6
F43.29
ICD-10 Finland
Adaptation disorder UNS
7.5
11.0
25
34
A02BC01
ATC
omeprazole; systemic
1.7
11.0
255
1663
B02.9
ICD-10 Finland
Zoster without complication
2.9
10.8
67
245
A01AB04
ATC
amphotericin B; local oral
3.0
10.7
63
223
6BA02
NOMESCO Finland
NA
28.4
10.7
14
5
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
21.7
10.7
15
7
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
10.5
97
445
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
111.2
10.4
11
*
1CX01
NOMESCO Finland
NA
111.2
10.4
11
*
360
Kela drug reimbursment
Bosutinib
+∞
10.4
10
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
10.4
10
*
L01BC06
ATC
capecitabine; oral
+∞
10.4
10
*
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
10.4
10
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
10.4
10
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
10.4
10
*
RS220
NOMESCO Finland
NA
6.9
10.4
25
37
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
32.9
10.3
13
*
ED1AA
NOMESCO Finland
Mandipular X-ray examination
19.0
10.3
15
8
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
23.7
10.3
14
6
HAB40
NOMESCO Finland
Wedge excision of mammary gland
13.3
10.2
17
13
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
10.0
51
164
PJA10
NOMESCO Finland
Exploration of lymph nodes
14.8
10.0
16
11
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.6
10.0
44
127
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.3
9.9
29
56
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
12.3
9.9
17
14
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
26.3
9.8
13
5
H26.3
ICD-10 Finland
Drug-induced cataract
20.3
9.8
14
7
L01AA02
ATC
chlorambucil; oral
55.6
9.7
11
*
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
55.6
9.7
11
*
B02AA02
ATC
tranexamic acid; systemic
2.1
9.6
109
548
D75.2
ICD-10 Finland
Essential thrombocytosis
8.5
9.6
20
24
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.7
9.5
41
116
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
101.0
9.4
10
*
B74
ICPC
Malignant neoplasm blood other
101.0
9.4
10
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
101.0
9.4
10
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
9.4
9
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
9.4
9
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
9.4
9
*
9867/3-C42.1
ICD-O-3
Acute myelomonocytic leukemia, NOS, of bone marrow
+∞
9.4
9
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
9.4
9
*
9801/3-C42.1
ICD-O-3
Acute leukemia, NOS, of bone marrow
+∞
9.4
9
*
2051A
ICD-9 Finland
Myeloid leukaemia, Chronic
+∞
9.4
9
*
E89.4
ICD-10 Finland
Postprocedural ovarian failure
+∞
9.4
9
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
9.4
9
*
20500
ICD-8 Finland
Myeloid leukaemia, Acute
+∞
9.4
9
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
9.4
9
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
9.4
9
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
9.4
9
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
9.4
9
*
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
21.9
9.4
13
6
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
9.2
171
1032
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.2
9.1
33
80
J01FF01
ATC
clindamycin; systemic
1.7
9.1
234
1563
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.0
404
3102
SPAT1074
SPAT
Venesection
18.8
8.9
13
7
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
8.9
67
277
ZX100
NOMESCO Finland
Oral
6.9
8.9
21
31
A98
ICPC
Health maint/preventive medicine
0.6
8.8
675
7522
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
8.7
176
1089
B37.7
ICD-10 Finland
Candidal sepsis
50.5
8.7
10
*
N05BA06
ATC
lorazepam; systemic, sublingual
2.6
8.6
61
242
1XC02
NOMESCO Finland
NA
16.5
8.6
13
8
N05CF01
ATC
zopiclone; oral
1.6
8.5
277
1961
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
8.5
154
920
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
90.8
8.4
9
*
M87.3
ICD-10 Finland
Other secondary osteonecrosis
90.8
8.4
9
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
90.8
8.4
9
*
Z51.0
ICD-10 Finland
Radiotherapy session
90.8
8.4
9
*
T86.9
ICD-10 Finland
Failure and rejection of unspecified transplanted organ and tissue
+∞
8.3
8
*
L03AA10
ATC
lenograstim; parenteral
+∞
8.3
8
*
L01EA04
ATC
bosutinib; oral
+∞
8.3
8
*
C91.7
ICD-10 Finland
Other lymphoid leukaemia
+∞
8.3
8
*
1BC01
NOMESCO Finland
NA
+∞
8.3
8
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
8.3
8
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
8.3
8
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
8.3
8
*
C92
ICD-10 Finland
Myeloid leukaemia
+∞
8.3
8
*
B59
ICD-10 Finland
Pneumocystosis
+∞
8.3
8
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
8.3
8
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
8.3
8
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
8.3
8
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
9.6
8.3
16
17
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.0
8.2
47
164
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
14.6
8.2
13
9
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
6.6
8.2
20
31
TPX15
NOMESCO Finland
Removal of vascular injection port
33.7
8.1
10
*
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
10.1
8.0
15
15
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
10.1
8.0
15
15
A07AA09
ATC
vancomycin; oral
5.9
8.0
21
36
WZC30
NOMESCO Finland
Teaching
2.2
7.9
82
399
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
7.9
25
54
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
7.8
84
414
2AX05
NOMESCO Finland
NA
45.4
7.7
9
*
A79
ICPC
Malignancy NOS
45.4
7.7
9
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.7
7.7
32
89
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.5
7.7
17
23
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.5
7.7
57
235
ZXH04
NOMESCO Finland
Procedure performed in other inpatient unit
25.2
7.6
10
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.7
7.5
31
86
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
7.5
41
141
H02AB07
ATC
prednisone; oral
1.8
7.5
125
729
174
Kela drug reimbursment
Ruxolitinib
80.7
7.4
8
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
80.7
7.4
8
*
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
11.0
7.3
13
12
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
7.3
7
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
7.3
7
*
C91.2
ICD-10 Finland
Subacute lymphocytic leukemia
+∞
7.3
7
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
7.3
7
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
7.3
7
*
373
Kela drug reimbursment
Ponatinib
+∞
7.3
7
*
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
+∞
7.3
7
*
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
7.3
7
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
7.3
7
*
153
Kela drug reimbursment
Lenalidomid
+∞
7.3
7
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
+∞
7.3
7
*
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
7.4
7.2
16
22
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
4.9
7.2
22
46
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.5
7.2
53
217
ZZR00
NOMESCO Finland
Flap of skin
12.1
7.1
12
10
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
12.1
7.1
12
10
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.1
7.1
36
118
XQ848
NOMESCO Finland
Dermatological photography
4.8
7.0
22
47
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.9
7.0
27
71
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.1
6.9
25
62
Z3226
NOMESCO Finland
Physiotherapist
1.7
6.9
146
914
L01AA01
ATC
cyclophosphamide; systemic
11.0
6.8
12
11
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
40.3
6.8
8
*
N06DX01
ATC
memantine; oral
0.3
6.7
10
382
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
6.5
6.7
16
25
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
12.3
6.6
11
9
RS221
NOMESCO Finland
NA
4.4
6.6
22
51
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
6.2
6.5
16
26
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.5
133
827
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.7
6.5
40
150
L01XE18
ATC
[U] ruxolitinib; oral
70.3
6.4
7
*
C50
ICD-10 Finland
Malignant neoplasm of breast
70.3
6.4
7
*
XX1AD
NOMESCO Finland
Other CT-examination
70.3
6.4
7
*
N89.5
ICD-10 Finland
Stricture and atresia of vagina
70.3
6.4
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
6.4
182
1234
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
8.2
6.3
13
16
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.2
6.3
8
336
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
6.3
25
68
K61.0
ICD-10 Finland
Anal abscess
4.6
6.3
20
44
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
18.2
6.3
9
5
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
18.2
6.3
9
5
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
18.2
6.3
9
5
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
6.3
88
481
L01BB05
ATC
fludarabine; systemic
+∞
6.3
6
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
6.3
6
*
9800/3-C42.1
ICD-O-3
Leukemia, NOS, of bone marrow
+∞
6.3
6
*
C94.0
ICD-10 Finland
Acute erythroid leukaemia
+∞
6.3
6
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
+∞
6.3
6
*
B01AC14
ATC
[U] anagrelide; oral
+∞
6.3
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.3
6
*
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
+∞
6.3
6
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
+∞
6.3
6
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
6.3
6
*
J05AX18
ATC
letermovir; oral
+∞
6.3
6
*
L01XE24
ATC
[U] ponatinib; oral
+∞
6.3
6
*
L04AX04
ATC
lenalidomide; oral
+∞
6.3
6
*
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
6.3
6
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
C84.59
ICD-10 Finland
Other and unspecified T-cell lymphomas
+∞
6.3
6
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
6.3
6
*
9109
FHL
Other measure in this category
26.9
6.2
8
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.1
6.1
65
321
R04.0
ICD-10 Finland
Epistaxis
2.1
6.1
69
349
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.7
6.0
14
21
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.1
6.0
11
11
L03.9
ICD-10 Finland
Cellulitis, unspecified
4.2
6.0
21
51
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.0
127
792
A01AB09
ATC
miconazole; local oral
2.0
6.0
75
395
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.1
6.0
15
25
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: CD2_MYELOID_LEUKAEMIA_EXALLC – Myeloid leukaemia
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).