Hepatocellular carcinoma, excluding all cancers (controls excluding all cancers)

C3_HEPATOCELLU_CARC_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C22.0&
  • Cause of death: ICD-10 C22.0&
  • Cancer registry: Topography ICD-O-3 C22
  • Cancer registry: Morphology ICD-O-3 817[0-5]
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

982

4. Check minimum number of events

None

982

5. Include endpoints

None

982

6. Filter based on genotype QC (FinnGen only)

982

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Hepatocellular carcinoma, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 982 172 810
Unadjusted period prevalence (%) 0.30 0.06 0.36
Median age at first event (years) 72.05 71.92 72.08

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
635
Matched controls
6351
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
+∞
323.0
600
*
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
+∞
323.0
503
*
130
Kela drug reimbursment
Malignant tumour
+∞
312.0
273
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
287.2
231.9
224
12
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
252.5
222.3
217
13
198
Kela drug reimbursment
Sorafenib
+∞
170.7
156
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
+∞
146.7
135
*
Z51.5
ICD-10 Finland
Palliative care
29.7
131.7
181
84
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
+∞
120.8
112
*
L01XE05
ATC
[U] sorafenib; oral
+∞
119.6
111
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
62.1
118.3
137
28
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
14.2
105.0
191
186
A03FA01
ATC
metoclopramide; systemic, rectal
10.6
96.0
206
276
N02AA05
ATC
oxycodone; systemic
8.3
95.8
246
447
JN4CD
NOMESCO Finland
Very extensive body CT
36.0
95.0
123
42
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
24.6
84.1
121
60
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
73.4
69
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
48.9
70.4
85
20
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
67.9
64
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
352.0
63.6
63
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
62.5
59
*
323
Kela drug reimbursment
Sorafenib
+∞
61.5
58
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
61.5
58
*
R18
ICD-10 Finland
Ascites
27.5
60.8
84
35
C03DA01
ATC
spironolactone; oral
5.3
57.2
205
523
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
15.7
57.2
96
71
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
25.2
55.2
78
35
JN4BD
NOMESCO Finland
Extensive body CT
9.1
53.8
120
158
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
36.1
52.9
68
21
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
40.7
52.8
66
18
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.5
49.5
165
380
Z94.4
ICD-10 Finland
Liver transplant status
+∞
47.5
45
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
18.6
46.8
73
44
JN4AD
NOMESCO Finland
Body CT examination
10.8
46.1
92
98
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
43.7
45.5
56
14
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
45.3
43
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.4
44.9
104
144
JJ6LT
NOMESCO Finland
Coagulation of focal hepatic lesion under ultrasound guidance
+∞
43.2
41
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.9
42.5
214
732
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
+∞
42.1
40
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
+∞
42.1
40
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.4
42.1
277
1172
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
10.5
40.8
82
88
WF002
NOMESCO Finland
Radical radiotherapy
+∞
38.9
37
*
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
70.9
35.4
40
6
A04AA02
ATC
granisetron; systemic, transdermal
355.1
34.3
34
*
116
Kela drug reimbursment
Prostate cancer
+∞
33.6
32
*
127
Kela drug reimbursment
Transplant complication
23.5
32.2
46
21
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
31.5
30
*
103
Kela drug reimbursment
Diabetes, insulin-treated
2.8
31.5
301
1556
A04AA01
ATC
ondansetron; systemic, rectal
19.1
31.5
48
27
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.9
31.1
111
265
3019
Kela drug reimbursment
Lenvatinib
+∞
30.5
29
*
L01EX02
ATC
sorafenib; oral
+∞
29.4
28
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
31.0
28.8
38
13
H02AB02
ATC
dexamethasone; systemic
21.3
28.6
42
21
N02AX02
ATC
tramadol; systemic, rectal
2.6
28.5
322
1798
C03CA01
ATC
furosemide; systemic
2.6
28.4
339
1953
1508
Kela drug reimbursment
Lenvatinib
+∞
28.3
27
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.7
28.1
264
1326
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
104.8
27.9
30
*
A10BA02
ATC
metformin; oral
2.6
27.8
295
1583
D77
ICPC
Malignant digestive neopl other/NOS
282.3
26.9
27
*
L04AA06
ATC
mycophenolic acid; systemic
16.6
26.3
42
27
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
25.2
24
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
36.1
24.5
31
9
A06AD11
ATC
lactulose; oral
2.9
24.5
177
745
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
24.1
23
*
WZC30
NOMESCO Finland
Teaching
4.2
23.5
96
259
176
Kela drug reimbursment
Regorafenib
+∞
23.1
22
*
K92.0
ICD-10 Finland
Haematemesis
6.6
22.9
60
98
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
86.7
22.8
25
*
K76.9
ICD-10 Finland
Liver disease, unspecified
16.5
22.6
36
23
JN3AD
NOMESCO Finland
Abdominal CT examination
4.5
22.0
83
207
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
22.0
21
*
L01EX08
ATC
lenvatinib; oral
+∞
22.0
21
*
L02AE02
ATC
leuprorelin; implant, parenteral
227.4
21.7
22
*
XX3DW
NOMESCO Finland
Time consuming IT work
5.4
21.3
66
133
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
37.1
20.0
25
7
A07AA11
ATC
rifaximin; oral
108.4
19.7
21
*
B01AB10
ATC
tinzaparin; parenteral
6.0
19.3
54
96
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
+∞
18.8
18
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
6.1
18.7
52
92
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
39.7
18.7
23
6
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
195.4
18.6
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
18.1
166
781
A05AA02
ATC
ursodeoxycholic acid; oral
17.2
18.0
28
17
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
17.8
162
760
C22
ICD-10 Finland
Malignant neoplasm of liver and intrahepatic bile ducts
+∞
17.8
17
*
JJ7LT
NOMESCO Finland
Coagulation of focal hepatic lesion under CT guidance
+∞
17.8
17
*
JJA44
NOMESCO Finland
Laparoscopic destruction of lesion of liver
+∞
17.8
17
*
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
9.5
17.6
36
40
A79
ICPC
Malignancy NOS
184.9
17.6
18
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.3
17.5
211
1138
T90
ICPC
Diabetes non-insulin dependent
2.3
17.4
207
1114
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
26.4
17.0
23
9
B01AB05
ATC
enoxaparin; parenteral
2.3
17.0
199
1059
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
65.1
16.8
19
*
UJF32
NOMESCO Finland
Coloscopy
2.4
16.8
179
908
JJ5AT
NOMESCO Finland
NA
+∞
16.7
16
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
16.7
16
*
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
16.7
16
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
16.7
16
*
JJB71
NOMESCO Finland
Laparoscopic resection of liver
+∞
16.7
16
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
16.7
16
*
JJB30
NOMESCO Finland
Excision of two segments of liver
+∞
16.7
16
*
A10AE04
ATC
insulin glargine; parenteral
2.9
16.7
110
425
L04AD01
ATC
ciclosporin; systemic
9.9
16.6
33
35
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
16.4
304
1967
A10BB12
ATC
glimepiride; oral
2.9
16.3
111
438
J01MA12
ATC
levofloxacin; systemic
2.5
16.1
152
722
B18.2
ICD-10 Finland
Chronic viral hepatitis C
25.2
16.1
22
9
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
+∞
15.7
15
*
A02BC02
ATC
pantoprazole; systemic
2.0
15.6
387
2786
WX402
NOMESCO Finland
General anaesthesia
3.1
15.6
89
313
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
163.8
15.5
16
*
D97
ICPC
Liver disease NOS
39.1
15.5
19
5
K92.1
ICD-10 Finland
Melaena
3.7
15.0
67
195
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
14.9
89
322
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
21.7
14.7
21
10
L01XE21
ATC
[U] regorafenib; oral
+∞
14.6
14
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
14.6
14
*
C22.7
ICD-10 Finland
Malignant neoplasm: Other specified carcinomas of liver
+∞
14.6
14
*
L02BB03
ATC
bicalutamide; oral
153.3
14.5
15
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.6
14.2
41
77
A10BH01
ATC
sitagliptin; oral
2.7
13.9
101
411
I81
ICD-10 Finland
Portal vein thrombosis
30.8
13.9
18
6
369
Kela drug reimbursment
Regorafenib
+∞
13.6
13
*
PC2SC
NOMESCO Finland
Liver angiography with X-ray
+∞
13.6
13
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
13.6
13
*
JN3GE
NOMESCO Finland
Intraoperative ultrasound examination of abdomen
+∞
13.6
13
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
34.8
13.6
17
5
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
13.5
103
434
K72.1
ICD-10 Finland
Chronic hepatic failure
26.4
13.4
18
7
TK800
NOMESCO Finland
Hemodialysis
6.1
13.3
36
62
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
8.6
13.1
28
34
KCD02
NOMESCO Finland
Transurethral resection of bladder
17.2
13.0
20
12
WW500
NOMESCO Finland
Blood transfusion
6.2
12.9
34
57
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.2
12.7
142
725
J01MA02
ATC
ciprofloxacin; systemic
1.9
12.6
264
1732
D13.4
ICD-10 Finland
Benign neoplasm: Liver
32.7
12.6
16
5
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
+∞
12.5
12
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
12.5
12
*
C07AA05
ATC
propranolol; systemic
2.6
12.5
97
413
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.8
12.2
82
319
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
16.3
12.2
19
12
SPAT1262
SPAT
Handing over of treatment supplies
2.1
12.0
152
820
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
11.5
11
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
122.1
11.5
12
*
TJA10
NOMESCO Finland
Laparocentesis
122.1
11.5
12
*
R4110
NOMESCO Finland
Physiotherapy
2.0
11.4
161
906
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
11.2
95
423
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.7
10.8
36
80
R50.9
ICD-10 Finland
Fever, unspecified
2.4
10.8
99
457
L01XE29
ATC
[U] lenvatinib; oral
+∞
10.4
10
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
10.4
10
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
10.4
10
*
JJA20
NOMESCO Finland
Open biopsy of liver
33.1
10.4
13
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
9.0
10.3
21
24
R4190
NOMESCO Finland
Nutritional therapy
9.3
10.1
20
22
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
40.7
10.0
12
*
205
Kela drug reimbursment
Chronic hypertension
1.7
9.7
265
1853
C10AA05
ATC
atorvastatin; oral
0.5
9.7
131
2065
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
5.6
9.6
27
50
K83.0
ICD-10 Finland
Cholangitis
6.3
9.5
24
39
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
101.4
9.4
10
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.2
9.4
102
510
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
30.5
9.4
12
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
12.6
9.4
16
13
1550A
ICD-9 Finland
Malignant neoplasm of liver and intrahepatic bile ducts, Liver, primary
+∞
9.4
9
*
JJB20
NOMESCO Finland
Excision of single segment of liver
+∞
9.4
9
*
JJA43
NOMESCO Finland
Destruction of lesion of liver
+∞
9.4
9
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
9.4
9
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
9.4
9
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
6.6
9.3
23
36
PC1BC
NOMESCO Finland
Extensive angiography of aorta and abdominal arteries
15.9
9.1
14
9
XX4BW
NOMESCO Finland
NA
24.4
8.9
12
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
8.9
130
734
A10AE05
ATC
insulin detemir; parenteral
2.8
8.8
58
223
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
50.7
8.7
10
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.2
8.6
86
415
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
8.6
112
606
ZXC40
NOMESCO Finland
Use of ultrasound
27.9
8.5
11
*
ZX120
NOMESCO Finland
Intravenous
2.8
8.5
55
211
L01EX05
ATC
regorafenib; oral
+∞
8.3
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
8.3
8
*
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
8.3
8
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
8.3
8
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
14.7
8.2
13
9
A98
ICPC
Health maint/preventive medicine
0.6
8.2
374
4461
SPAT1109
SPAT
Analgesia with portable analgesic pump
33.8
8.1
10
*
N02AA01
ATC
morphine; systemic, rectal
9.1
8.1
16
18
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.0
8.0
21
36
N05CF01
ATC
zopiclone; oral
1.7
8.0
205
1388
E66.00
ICD-10 Finland
Metabolic syndrome
3.0
7.9
43
148
A10BG03
ATC
pioglitazone; oral
3.7
7.9
33
93
UJK02
NOMESCO Finland
ERCP
4.4
7.8
27
64
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.5
7.7
35
105
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
7.7
171
1107
XF612
NOMESCO Finland
Measurement of central venous pressure
45.5
7.7
9
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.0
7.6
29
75
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
6.8
7.6
18
27
A06AH03
ATC
naloxegol; oral
18.6
7.6
11
6
L04AX01
ATC
azathioprine; systemic
3.8
7.6
30
81
K83.1
ICD-10 Finland
Obstruction of bile duct
7.2
7.5
17
24
ZX050
NOMESCO Finland
Stereotactic radiotherapy
81.0
7.4
8
*
K70.1
ICD-10 Finland
Alcoholic hepatitis
9.5
7.3
14
15
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
7.3
7
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
7.3
7
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
7.3
7
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
7.3
7
*
JJB40
NOMESCO Finland
Excision of segments II, III and IV of liver
+∞
7.3
7
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
7.3
7
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
7.3
7
*
JAH00
NOMESCO Finland
Laparotomy
4.4
7.3
25
59
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.8
7.3
44
163
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
7.2
35
780
N06DX01
ATC
memantine; oral
0.3
7.2
11
414
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
30.4
7.2
9
*
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
30.4
7.2
9
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
7.1
29
691
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
7.1
55
232
K70.0
ICD-10 Finland
Alcoholic fatty liver
7.1
7.0
16
23
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
7.0
79
403
UJD02
NOMESCO Finland
Gastroscopy
2.9
6.9
41
150
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
14.0
6.9
11
8
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
14.0
6.9
11
8
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
11.1
6.8
12
11
K76.89
ICD-10 Finland
Other specified diseases of liver
22.8
6.7
9
*
XQ902
NOMESCO Finland
Other photography
22.8
6.7
9
*
WX882
NOMESCO Finland
High dependency care
3.8
6.6
26
70
G04CA52
ATC
tamsulosin and dutasteride; systemic
0.4
6.5
31
692
K76.6
ICD-10 Finland
Portal hypertension
70.5
6.4
7
*
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
70.5
6.4
7
*
Y77
ICPC
Malignant neoplasm prostate
70.5
6.4
7
*
WW200
SPAT
NA
0.2
6.4
5
276
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
6.3
41
159
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.9
6.3
36
128
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
18.2
6.3
9
5
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
+∞
6.3
6
*
TJA40
NOMESCO Finland
Percutaneous local drainage of peritoneal cavity
+∞
6.3
6
*
8000/3-C80.9
ICD-O-3
Neoplasm, malignant of unknown primary site
+∞
6.3
6
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
6.3
6
*
C22.2
ICD-10 Finland
Malignant neoplasm: Hepatoblastoma
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
6.3
6
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
26.9
6.2
8
*
A10BD07
ATC
metformin and sitagliptin; systemic
2.7
6.2
40
154
K72.9
ICD-10 Finland
Hepatic failure, unspecified
12.7
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
517
382
27.47
307.65
4.2
1.4
4.5
3.8
ug/l
0.25
451
290
227
19
155.09
307.65
1.9
1.4
—
—
—
0
0
288
176
22.74
307.65
5.2
2.2
43.5
34.6
umol/l
2.81
255
150
376
132
45.54
307.65
4.1
1.9
206.5
105.2
u/ml
0.33
338
103
451
559
14.07
307.65
6.0
1.9
0.2
0.2
g/l
7.01
427
491
235
157
19.36
276.70
1.6
1.1
64.4
85.8
titre
0.39
16
12
179
74
29.36
258.78
1.4
1.0
1.6
1.6
g/l
0.71
174
63
411
691
9.51
257.32
12.2
2.5
16.8
10.3
umol/l
2.46
391
600
182
80
27.70
257.18
2.5
1.6
82.4
57.0
u/ml
0.29
173
70
234
198
15.20
240.62
1.6
1.3
—
—
—
0
0
315
468
9.44
215.79
1.7
1.4
—
—
—
0
0
304
461
9.10
203.90
1.7
1.5
—
—
—
0
0
92
11
92.18
175.30
5.0
3.3
—
—
—
0
0
343
694
7.06
174.25
12.7
6.4
8.7
11.5
mmol/l
8.21
330
647
73
19
41.43
119.96
4.5
2.0
—
—
—
0
0
521
1993
4.44
117.57
13.8
2.6
64.0
36.0
u/l
6.84
508
1874
466
1663
4.43
115.14
17.3
3.7
73.2
80.5
%
8.18
456
1609
651
3028
4.41
109.63
17.2
3.8
31.8
34.9
g/l
31.25
629
2752
65
18
38.60
104.92
2.2
2.0
971.4
94862.0
e6/l
0.47
41
11
185
336
6.55
101.08
1.8
1.3
1.7
1.2
g/l
2.35
169
301
61
16
40.58
99.80
2.1
2.1
—
—
—
0
0
679
3396
4.24
99.67
25.5
3.9
24.1
13.2
umol/l
10.78
664
3179
161
262
7.15
97.71
1.4
1.4
—
—
—
0
0
59
15
41.78
97.25
1.2
4.3
—
—
—
0
0
60
18
35.44
94.61
1.0
1.0
—
—
—
0
0
323
999
4.33
94.11
2.8
2.5
25.5
22.6
%
2.02
294
830
331
1050
4.25
93.05
4.9
2.7
0.8
0.8
mmol/l
12.05
318
957
59
18
34.81
92.56
1.0
1.1
—
—
—
0
0
196
414
5.67
90.94
2.2
2.0
13.9
11.2
g/l
9.50
182
371
123
163
8.48
89.28
5.2
3.0
1.7
1.7
mg/l
0.05
114
142
105
116
10.02
87.88
2.5
1.3
—
—
—
0
0
324
1060
4.07
86.49
2.7
2.4
2.3
2.2
g/l
1.33
305
968
70
41
18.31
85.81
2.3
2.3
—
—
—
0
0
220
539
4.97
85.73
4.4
2.2
31.7
34.6
u/l
0.53
196
433
69
41
18.03
83.97
1.2
1.1
—
—
—
0
0
75
54
14.95
82.61
1.3
1.3
180.9
209.0
titre
—
11
10
53
17
32.90
81.80
2.1
2.8
—
—
—
0
0
625
3281
3.49
77.85
19.2
11.9
1.3
1.4
inr
2.55
157
915
83
81
11.10
75.69
1.3
1.4
111.3
110.6
u/ml
—
6
12
325
1160
3.69
75.03
2.8
2.4
13.7
12.6
umol/l
1.51
311
1047
82
86
10.31
71.03
1.2
1.2
360.9
250.3
u/ml
1.66
55
46
469
2160
3.24
70.92
5.6
2.3
59.6
58.9
u/l
0.12
455
1974
85
94
9.80
70.83
1.3
1.3
—
—
—
0
0
441
2003
3.18
67.57
4.2
2.2
—
—
—
0
0
368
1556
3.18
62.96
4.1
2.2
—
—
—
0
0
43
17
26.41
61.76
1.9
1.2
9.0
12.1
g/l
—
29
10
173
468
4.27
58.17
1.4
1.1
—
—
—
0
0
45
25
18.82
56.25
1.2
1.2
—
—
—
0
0
86
131
7.10
54.75
1.2
1.2
—
—
—
0
0
72
90
8.55
54.37
1.2
1.2
—
—
—
0
0
49
37
13.89
52.26
1.2
1.1
—
—
—
0
0
48
35
14.37
52.21
1.1
1.0
—
—
—
0
0
34
11
31.98
52.00
1.1
1.1
—
—
—
0
0
535
2999
2.72
51.52
7.1
3.7
—
—
—
0
0
50
43
12.20
49.28
1.0
1.0
272.3
287.8
mg/l
0.48
44
38
253
977
3.14
48.98
7.8
5.2
1.0
1.0
mmol/l
0.60
238
884
194
687
3.27
43.01
10.3
7.5
—
—
—
0
0
585
3624
2.52
42.92
15.1
6.0
4.0
4.5
e9/l
5.45
533
3106
422
2251
2.53
42.86
6.1
4.2
—
—
—
0
0
201
733
3.19
42.38
1.6
1.3
288.0
476.3
titre
1.80
45
174
385
2045
2.45
38.55
6.3
3.2
7.4
7.4
ph
0.06
80
361
183
679
3.08
37.13
9.2
6.7
1.8
1.5
mmol/l
1.54
174
644
614
4051
2.38
36.77
13.4
3.0
201.7
53.4
u/l
37.41
590
3657
137
433
3.51
36.10
10.9
9.3
—
—
—
0
0
208
852
2.83
35.14
1.4
1.2
—
—
—
0
0
165
602
3.09
34.31
1.4
1.5
—
—
—
0
0
553
3566
2.26
33.87
11.0
5.7
1.2
1.2
mmol/l
9.13
475
2988
54
84
6.74
33.54
1.1
1.0
—
—
—
0
0
346
1853
2.34
32.98
2.5
1.6
—
—
—
0
0
234
1059
2.59
32.22
2.8
2.1
—
—
—
0
0
245
1146
2.52
31.38
3.3
2.8
1.2
1.3
e6/l
0.11
145
640
513
3281
2.18
31.15
10.2
5.3
1.2
1.2
mmol/l
7.51
493
2890
195
820
2.72
31.03
4.2
3.3
0.8
2.0
mmol/l
4.37
151
644
384
2199
2.23
30.72
7.3
5.2
—
—
—
0
0
296
1522
2.35
30.64
11.9
4.6
—
—
—
0
0
194
822
2.69
30.36
4.1
3.3
5.5
5.9
kpa
4.43
189
786
219
987
2.57
30.23
9.8
6.8
12.7
11.2
kpa
4.78
212
937
219
987
2.57
30.23
9.8
6.8
5.0
5.1
kpa
1.23
212
940
354
1985
2.22
29.61
4.2
3.0
1.1
0.4
e6/l
2.26
285
1502
217
985
2.54
29.44
9.7
6.8
0.1
1.3
mmol/l
4.67
181
752
52
89
6.11
29.41
1.1
1.1
—
—
—
0
0
341
1891
2.23
29.25
4.2
3.0
—
—
—
0
0
202
891
2.60
29.06
10.2
7.1
96.4
94.7
%
3.09
197
856
249
1214
2.41
28.87
3.2
2.6
0.8
1.0
e6/l
1.08
150
702
619
4366
2.13
27.90
13.3
4.7
7.7
7.0
mmol/l
8.67
599
4103
28
24
11.98
27.47
3.4
2.2
—
—
—
0
0
211
979
2.47
27.12
1.8
1.2
4.4
2.9
g/l
10.64
176
553
374
2210
2.12
26.81
4.4
3.1
77.8
123.0
e6/l
0.52
301
1711
464
3057
1.98
23.88
8.8
5.7
9.6
9.0
%
2.70
439
2810
468
3108
1.97
23.38
8.6
5.5
23.5
25.6
%
3.63
441
2840
450
2954
1.97
23.21
8.6
5.4
0.6
0.6
%
0.58
423
2715
690
5245
2.06
23.20
28.1
5.3
152.2
78.0
u/l
45.42
670
4809
460
3044
1.96
23.16
8.5
5.4
2.7
3.0
%
1.76
436
2789
266
1447
2.15
23.07
3.5
2.6
562.4
567.5
mosm/kgh2o
0.15
242
1214
490
3330
1.94
22.63
8.3
5.2
1.5
1.8
e9/l
9.89
431
2871
482
3260
1.94
22.55
8.4
5.1
0.6
0.6
e9/l
0.92
419
2764
483
3278
1.93
22.28
8.4
5.1
0.0
0.0
e9/l
2.61
419
2785
491
3377
1.91
21.49
8.7
5.2
0.2
0.2
e9/l
3.29
432
2916
392
2511
1.93
21.24
5.0
3.5
74.9
116.7
e6/l
0.73
311
1828
457
3083
1.90
21.11
8.3
5.4
60.3
58.9
%
1.56
433
2840
348
2182
1.92
19.79
6.5
2.0
2.3
2.3
mmol/l
1.96
325
1761
236
1293
2.09
19.71
6.5
2.1
2.5
2.4
mmol/l
9.21
221
1082
389
2601
1.82
17.59
3.9
2.8
179.4
164.3
ug/l
0.50
365
2343
309
1945
1.86
16.84
2.8
2.3
3.7
3.0
mg/l
4.18
271
1628
258
1533
1.93
16.80
3.6
2.4
5.4
3.8
e6/l
1.36
243
1335
580
4540
1.68
13.68
5.1
4.3
524.4
2708.9
e6/l
—
8
90
121
595
2.18
13.04
1.5
1.3
—
—
—
0
0
253
1615
1.76
12.60
1.6
1.3
—
—
—
0
0
381
2722
1.65
12.47
4.4
4.0
10.0
7.6
mg/mmol
0.74
274
1817
112
554
2.15
11.87
4.9
3.0
1.2
1.2
mmol/l
0.87
105
469
33
84
4.03
11.81
2.0
1.7
0.6
1.1
g/l
1.64
23
66
217
1353
1.78
11.61
1.9
1.7
2.9
1.4
mg/l
3.40
183
1048
56
203
2.86
11.56
4.2
3.5
—
—
—
0
0
363
2611
1.62
11.30
3.6
3.2
7.3
7.9
mmol/l
2.31
300
2186
208
1297
1.77
11.08
20.3
30.1
1.5
1.5
inr
0.10
18
182
24
50
4.90
11.00
1.5
1.4
—
—
—
0
0
296
2035
1.65
10.98
3.2
3.0
—
—
—
0
0
63
257
2.55
10.37
3.9
2.4
0.2
0.2
g/l
0.00
44
92
350
2577
1.56
9.47
3.5
3.3
541.7
192.5
mg/l
0.66
260
1730
134
772
1.85
9.18
1.9
1.4
—
—
—
0
0
116
638
1.93
9.16
2.7
1.6
66.3
66.7
g/l
0.17
104
564
46
173
2.74
8.91
6.2
4.6
1.8
2.5
mmol/l
1.75
31
112
51
203
2.60
8.85
6.2
4.4
7.4
7.4
ph
0.28
44
169
45
172
2.69
8.46
4.2
3.8
—
—
—
0
0
17
33
5.22
8.43
2.1
2.6
—
—
—
0
0
592
6817
0.67
8.29
6.0
4.8
4.0
4.3
mmol/l
8.82
539
6214
572
4755
1.49
8.28
5.2
4.0
—
—
—
0
0
20
675
0.28
8.24
1.4
1.5
—
—
—
0
0
381
2924
1.50
8.21
20.5
8.8
0.0
0.0
e9/l
0.90
306
2368
139
837
1.77
8.21
2.7
3.2
225.0
275.6
ng/l
0.84
128
781
163
1034
1.69
7.98
2.5
2.0
1.9
1.7
%
1.31
149
898
602
6892
0.67
7.97
5.7
5.0
6.8
6.2
mmol/l
13.40
537
6159
277
2000
1.54
7.93
4.3
2.6
4239.2
7751.5
umol/l
0.60
244
1686
76
379
2.09
7.89
1.6
1.6
1.1
1.5
g/l
2.08
62
320
170
2509
0.61
7.82
2.5
2.7
0.9
0.8
ug/l
0.82
110
1748
140
858
1.74
7.76
1.6
1.8
—
—
—
0
0
617
7017
0.68
7.73
6.2
5.5
2.3
2.5
mmol/l
6.73
556
6353
193
1298
1.61
7.49
5.5
3.9
—
—
—
0
0
72
363
2.06
7.27
6.4
4.3
0.9
0.9
%
0.05
66
346
591
6745
0.69
7.19
5.9
4.8
1.2
1.4
mmol/l
16.87
531
6096
21
57
3.74
6.94
3.2
3.0
—
—
—
0
0
104
611
1.79
6.66
6.2
4.7
—
—
—
0
0
36
140
2.63
6.60
1.3
1.4
58.8
65.5
mmol/l
0.36
24
111
365
4491
0.70
6.49
4.1
4.0
2.1
2.2
ug/l
0.12
301
3994
90
510
1.84
6.49
5.4
3.7
0.8
0.7
%
0.10
33
135
95
551
1.80
6.35
3.4
1.7
396.6
363.9
nmol/l
0.81
88
491
39
161
2.48
6.34
1.2
1.4
328.9
282.1
ug/g
0.75
22
97
228
1647
1.50
6.33
4.0
4.2
447.1
487.2
ng/l
0.08
202
1439
99
582
1.78
6.33
8.7
6.9
23.2
24.6
mmol/l
2.56
94
541
10
15
6.72
6.32
1.0
1.0
—
—
—
0
0
575
6525
0.71
6.09
5.4
4.3
1.4
1.3
mmol/l
2.13
517
5848
58
296
2.02
5.71
1.2
1.3
—
—
—
0
0
84
486
1.80
5.68
5.6
3.8
0.1
0.1
%
0.01
32
122
54
273
2.03
5.47
7.6
5.6
2.2
1.3
mmol/l
1.24
47
246
79
455
1.80
5.43
4.9
3.7
0.5
0.5
%
0.03
24
95
41
187
2.24
5.38
2.4
1.4
—
—
—
0
0
25
90
2.82
5.33
3.2
3.1
2.5
1.3
%
0.50
18
60
5
0
+∞
5.21
1.0
0.0
—
—
—
0
0
49
244
2.06
5.18
2.6
1.5
34.0
39.2
mg/l
0.57
37
198
49
245
2.05
5.12
2.6
1.5
50.3
49.1
mg/l
0.06
37
198
77
455
1.75
4.87
5.8
3.8
0.0
0.9
%
0.55
26
100
146
2031
0.67
4.75
4.3
3.3
—
—
—
0
0
17
53
3.25
4.63
1.2
1.1
—
—
—
0
0
29
122
2.42
4.60
1.3
1.4
8.6
6.5
u/l
0.78
19
100
50
264
1.94
4.52
2.2
2.3
147.6
102.8
ug/min
0.30
34
165
327
2656
1.35
4.46
2.8
3.2
1261.4
1820.0
ng/l
1.15
284
2299
36
172
2.13
4.27
3.5
2.5
14.9
16.5
%
0.91
13
95
24
97
2.51
4.15
1.9
1.5
32751.3
93580.5
e6/l
0.47
18
59
24
98
2.49
4.07
3.0
2.9
55.2
59.4
%
0.89
24
98
22
86
2.59
4.07
2.2
1.6
—
—
—
0
0
114
779
1.52
4.07
2.2
2.1
76.3
67.2
e9/l
1.45
83
605
20
75
2.70
4.01
2.1
1.5
—
—
—
0
0
85
549
1.60
3.88
2.4
1.5
—
—
—
0
0
26
113
2.34
3.87
1.2
1.6
—
—
—
0
0
154
1129
1.43
3.86
1.2
1.2
1.5
1.5
u/ml
0.04
28
303
23
96
2.43
3.75
2.9
2.7
3.5
4.7
e9/l
1.83
23
96
5
196
0.25
3.56
1.0
1.1
—
—
—
0
0
54
317
1.74
3.55
4.9
4.4
2.1
1.5
mmol/l
0.97
54
310
217
1710
1.35
3.52
1.9
1.8
1110.5
1165.4
nmol/l
0.38
163
1301
8
13
6.19
3.50
1.0
2.3
—
—
—
0
0
611
6668
0.78
3.47
10.2
6.7
45.0
41.4
mmol/mol
9.46
559
6090
82
540
1.57
3.47
3.6
3.8
89.1
96.1
ng/l
0.38
76
458
21
89
2.39
3.33
2.0
1.5
—
—
—
0
0
142
1873
0.72
3.32
2.3
1.6
1.7
1.3
mmol/l
3.39
132
1524
17
65
2.64
3.31
2.4
3.3
—
—
—
0
0
712
7598
0.77
3.19
55.1
21.3
6.7
6.9
e9/l
1.57
680
7270
712
7598
0.77
3.19
55.6
21.4
124.4
136.9
g/l
59.93
688
7395
712
7597
0.77
3.18
55.1
21.2
4.2
4.5
e12/l
40.02
680
7263
712
7596
0.77
3.17
54.9
21.2
91.7
91.8
fl
0.15
690
7393
712
7596
0.77
3.17
54.8
21.2
30.4
30.6
pg
1.21
689
7395
712
7595
0.77
3.15
55.1
21.3
189.4
232.4
e9/l
32.79
682
7303
56
876
0.62
3.12
1.1
1.2
18.2
15.6
u/ml
0.08
20
318
61
931
0.63
3.05
1.2
1.3
18.6
40.2
iu/ml
3.77
23
281
8
17
4.74
2.92
1.3
1.6
—
—
—
0
0
22
102
2.18
2.88
1.6
2.3
—
—
—
0
0
19
83
2.31
2.85
1.8
2.5
813.2
636.9
ml
0.88
11
57
13
47
2.79
2.82
1.5
1.6
12.5
14.8
umol/l
0.58
13
40
42
249
1.72
2.73
3.1
1.4
36.7
36.8
g/l
0.06
35
202
78
539
1.49
2.70
4.2
3.8
—
—
—
0
0
11
278
0.39
2.66
1.2
1.4
—
—
—
0
0
56
361
1.58
2.65
6.6
4.9
—
—
—
0
0
22
106
2.10
2.64
1.6
2.2
4.2
4.1
mmol/l
0.56
22
106
22
106
2.10
2.64
1.6
2.2
107.6
105.4
mmol/l
1.28
22
106
49
306
1.63
2.64
2.4
1.8
—
—
—
0
0
16
68
2.38
2.56
1.1
1.2
1.8
1.6
nmol/l
0.21
16
57
569
6162
0.82
2.47
4.8
4.1
2.5
2.0
mu/l
3.68
511
5460
20
96
2.11
2.44
6.0
3.8
—
—
—
0
0
15
64
2.36
2.39
1.4
1.3
2.3
8.2
u/ml
—
10
33
36
213
1.72
2.39
3.6
3.7
—
—
—
0
0
81
585
1.42
2.26
3.0
2.3
169.6
172.9
ug/g
0.04
62
453
11
42
2.64
2.19
1.0
1.1
—
—
—
0
0
13
55
2.38
2.12
1.8
1.3
0.7
1.2
promille
0.64
13
44
694
7326
0.82
2.09
32.6
9.2
41.9
26.4
u/l
33.51
678
6955
7
20
3.52
2.05
1.3
1.1
—
—
—
0
0
204
1709
1.24
2.02
4.1
3.3
—
—
—
0
0
31
186
1.69
1.99
2.1
2.7
—
—
—
0
0
12
51
2.37
1.95
1.1
1.2
—
—
—
0
0
47
315
1.52
1.94
1.4
1.5
4.5
40.2
u/ml
—
6
7
6
16
3.77
1.93
1.7
1.5
—
—
—
0
0
33
204
1.64
1.91
3.0
3.1
8.3
7.8
kpa
1.00
28
187
442
4830
0.85
1.86
4.1
3.3
14.6
15.1
pmol/l
3.94
397
4266
16
80
2.02
1.80
1.2
1.1
—
—
—
0
0
14
67
2.11
1.76
2.1
1.3
—
—
—
0
0
706
7396
0.84
1.69
46.2
18.3
4.0
4.0
mmol/l
0.90
683
7144
6
19
3.17
1.66
1.5
1.4
—
—
—
0
0
369
3328
1.17
1.65
4.4
3.5
0.0
0.0
estimate
0.00
77
580
54
387
1.42
1.63
2.5
2.4
—
—
—
0
0
5
14
3.58
1.61
1.2
1.0
—
—
—
0
0
5
14
3.58
1.61
2.2
1.1
—
—
—
0
0
12
56
2.16
1.61
1.6
1.2
—
—
—
0
0
72
544
1.35
1.60
1.2
1.5
—
—
—
0
0
23
136
1.71
1.60
1.3
1.2
—
—
—
0
0
15
77
1.96
1.59
1.1
1.1
—
—
—
0
0
367
3317
1.17
1.59
5.9
4.7
0.0
0.0
estimate
0.00
74
582
6
20
3.01
1.58
1.2
1.1
—
—
—
0
0
706
7382
0.84
1.58
46.0
18.2
138.1
139.7
mmol/l
39.32
686
7136
11
50
2.21
1.57
2.5
2.4
—
—
—
0
0
36
240
1.52
1.56
3.5
3.2
22.1
25.0
mmol/l
2.54
29
208
39
265
1.49
1.55
5.9
4.9
4.0
4.0
mmol/l
0.07
39
246
54
391
1.40
1.55
3.6
3.1
—
—
—
0
0
27
170
1.60
1.50
3.3
2.8
—
—
—
0
0
92
728
1.29
1.49
3.0
3.3
—
—
—
0
0
349
3155
1.16
1.49
4.5
4.2
30.7
79.0
ng/l
2.38
295
2435
71
545
1.33
1.44
2.9
3.5
7.4
7.4
ph
—
8
65
6
22
2.74
1.43
1.0
1.0
1620.3
1567.4
miu/ml
—
6
22
36
246
1.48
1.42
3.7
3.1
4.1
4.4
pmol/l
0.84
31
214
13
67
1.95
1.38
3.4
3.1
62.4
55.2
%
—
7
39
12
223
0.53
1.38
1.4
1.5
—
—
—
0
0
9
41
2.21
1.37
1.1
1.4
—
—
—
0
0
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
0
39
0.00
1.34
0.0
2.2
—
—
—
0
0
27
176
1.55
1.32
1.4
1.2
—
—
—
0
0
38
531
0.70
1.32
1.4
1.4
—
—
—
0
0
5
18
2.79
1.28
1.6
1.9
—
—
—
0
0
368
3371
1.15
1.28
4.4
3.5
0.0
0.0
estimate
0.00
67
562
8
35
2.30
1.27
1.5
1.9
—
—
—
0
0
71
557
1.30
1.26
3.0
3.5
4.8
5.2
kpa
3.37
59
506
17
275
0.61
1.21
20.9
11.6
—
—
—
0
0
188
1650
1.17
1.16
3.9
3.4
—
—
—
0
0
0
34
0.00
1.16
0.0
2.0
—
—
—
0
0
55
422
1.32
1.16
3.3
2.5
0.6
0.3
e6/l
0.40
55
414
16
95
1.70
1.14
2.6
2.7
—
—
—
0
0
13
73
1.79
1.11
1.2
1.2
—
—
nmol/l
—
0
0
8
41
1.96
1.09
1.1
1.4
—
—
—
0
0
7
33
2.13
1.05
3.0
2.2
—
—
—
0
0
5
22
2.28
1.03
1.0
1.3
—
—
—
0
0
14
227
0.61
1.03
1.1
1.3
—
—
—
0
0
26
182
1.44
0.96
1.2
1.1
—
—
—
0
0
25
175
1.44
0.93
1.7
1.6
—
—
—
0
0
23
160
1.45
0.89
1.1
1.3
0.6
0.8
nmol/l
1.25
17
134
12
71
1.70
0.89
1.3
1.5
—
—
—
0
0
12
71
1.70
0.89
1.3
1.5
—
—
—
0
0
12
71
1.70
0.89
1.3
1.5
—
—
—
0
0
12
71
1.70
0.89
1.3
1.5
—
—
—
0
0
197
1773
1.14
0.88
1.9
1.7
441.9
17103861.3
pmol/l
1.26
160
1450
6
30
2.01
0.87
1.7
2.1
1621.7
2095.6
ml
—
6
25
101
865
1.19
0.86
2.5
2.6
6.7
7.7
ug/l
0.23
84
751
32
239
1.35
0.85
1.2
1.2
—
—
—
0
0
574
5499
1.11
0.83
50.6
17.5
15.1
13.8
%
54.02
566
5329
11
177
0.62
0.82
1.0
1.1
—
—
—
0
0
12
73
1.65
0.82
1.2
1.3
—
—
—
0
0
354
3315
1.11
0.80
2.1
2.1
83.6
91.1
pmol/l
2.40
177
1764
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
617
5944
1.10
0.77
41.6
16.3
36.4
39.6
%
13.00
415
3648
690
7107
0.90
0.77
35.4
14.3
—
—
—
0
0
6
34
1.77
0.76
1.7
1.3
—
—
—
0
0
13
83
1.57
0.75
1.4
1.2
—
—
—
0
0
10
60
1.67
0.72
1.7
1.3
—
—
—
0
0
11
69
1.60
0.68
1.5
1.3
—
—
—
0
0
5
27
1.86
0.68
1.6
1.1
—
—
—
0
0
5
27
1.86
0.68
1.8
1.1
791.6
226.3
iu/ml
—
5
27
705
6863
1.10
0.64
38.6
14.8
31.9
27.4
mg/l
3.07
676
5433
203
1870
1.11
0.63
4.9
3.7
0.0
0.0
estimate
0.50
62
545
12
79
1.53
0.62
1.3
1.2
2.0
0.6
nmol/l
0.50
12
74
0
20
0.00
0.60
0.0
5.8
—
—
—
0
0
33
266
1.25
0.56
1.2
1.2
34.8
117.6
iu/ml
—
8
104
6
37
1.63
0.55
1.0
1.2
110.3
139.4
nmol/l
—
6
37
247
2314
1.09
0.55
4.7
4.2
—
—
—
0
0
264
2482
1.09
0.54
2.0
2.2
210.5
282.3
u/l
0.74
250
2304
529
5110
1.08
0.54
5.1
4.3
—
—
—
0
0
9
64
1.41
0.51
1.9
2.0
10.4
10.7
%
—
9
64
10
67
1.50
0.49
1.4
1.1
—
—
—
0
0
7
46
1.53
0.48
2.0
2.9
—
—
—
0
0
11
76
1.45
0.48
1.1
1.2
342.4
91.9
mu/l
0.39
11
67
7
50
1.40
0.45
2.4
2.7
—
—
—
0
0
10
69
1.45
0.44
1.0
1.4
570.2
260.9
pmol/l
—
10
50
548
5626
0.94
0.41
49.9
19.5
331.6
332.9
g/l
2.46
539
5557
0
15
0.00
0.41
0.0
2.9
—
—
—
0
0
14
105
1.34
0.41
2.3
2.6
—
—
—
0
0
16
205
0.78
0.40
1.4
1.5
26710.9
15911.7
e6/l
—
10
150
46
400
1.16
0.39
2.5
3.6
—
—
—
0
0
6
43
1.40
0.35
1.2
1.7
—
—
—
0
0
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
150
1595
0.93
0.34
5.7
3.8
1.0
1.0
kg/l
1.72
34
251
18
145
1.25
0.34
1.6
1.1
58.1
21.6
u/l
0.72
18
128
15
186
0.80
0.31
1.2
1.4
—
—
—
0
0
7
54
1.30
0.30
2.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.6
1.8
—
—
—
0
0
8
111
0.72
0.28
1.1
1.1
—
—
—
0
0
8
67
1.20
0.26
1.1
1.3
—
—
—
0
0
6
85
0.70
0.24
1.2
1.8
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
13.2
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
15
127
1.18
0.19
1.1
1.1
—
—
—
0
0
36
329
1.10
0.18
2.2
3.8
23.3
24.7
mmol/l
2.24
31
300
7
60
1.17
0.18
1.1
1.1
—
—
—
0
0
7
61
1.15
0.17
1.7
1.3
—
—
—
0
0
13
151
0.86
0.16
1.3
1.3
0.5
55.6
e6/l
—
8
126
515
5085
1.03
0.14
5.4
3.9
23.4
12.8
mm/h
19.71
472
4612
10
84
1.19
0.14
1.4
1.4
—
—
—
0
0
45
424
1.06
0.12
1.6
3.1
4.5
4.3
e9/l
0.13
35
292
29
271
1.07
0.10
1.9
1.7
—
—
—
0
0
18
164
1.10
0.09
1.5
2.0
207.4
217.4
pmol/l
0.22
18
152
5
60
0.83
0.08
18.0
15.2
—
—
—
0
0
7
65
1.08
0.08
2.1
1.2
—
—
—
0
0
7
66
1.06
0.08
2.1
1.2
—
—
—
0
0
7
66
1.06
0.08
2.1
1.2
—
—
—
0
0
7
68
1.03
0.08
2.1
1.2
—
—
—
0
0
7
68
1.03
0.08
2.1
1.2
—
—
—
0
0
14
128
1.10
0.06
1.3
1.4
—
—
—
0
0
9
105
0.86
0.06
1.6
1.1
—
—
—
0
0
64
659
0.97
0.06
4.0
2.8
—
—
—
0
0
198
1953
1.02
0.06
1.8
1.6
16.8
19.8
nmol/l
2.60
174
1637
13
120
1.08
0.05
2.0
2.3
—
—
—
0
0
59
575
1.03
0.04
2.5
2.2
13.4
15.0
nmol/l
0.53
47
499
37
379
0.98
0.02
1.2
1.3
—
—
—
0
0
48
486
0.99
0.00
3.4
2.8
—
—
—
0
0
41
406
1.01
0.00
1.2
1.2
—
—
—
0
0
16
158
1.01
0.00
1.9
1.9
—
—
—
0
0
14
141
0.99
0.00
1.1
1.5
—
—
—
0
0
11
115
0.96
0.00
1.1
1.6
—
—
—
0
0
5
57
0.88
0.00
2.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.0
—
0
5
0
6
0.00
0.00
0.0
21.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.2
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
400.6
—
0
8
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
6.4
—
8.3
—
0
9
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_HEPATOCELLU_CARC_EXALLC – Hepatocellular carcinoma, excluding all cancers (controls excluding all cancers)

GWS hits: 3

This endpoint is excluded (different definition than used in FinnGen).