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Adenocarcinoma and ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

Endpoint Browser PheWeb

C3_PANCREAS_ADENO_DUCTAL_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 — C25
  • Cancer registry: Morphology ICD-O-3 — 8140|8500
  • Cancer registry: Behaviour codes — 3

1 out of 7 registries used, show all original rules.

1159

4. Check minimum number of events

None

1159

5. Include endpoints

None

1159

6. Filter based on genotype QC (FinnGen only)

1159

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Adenocarcinoma and ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1159 490 669
Unadjusted period prevalence (%) 0.24 0.17 0.29
Median age at first event (years) 70.13 69.87 70.32

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1063
Matched controls
10630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
199.6
323.0
444
38
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
+∞
323.0
460
*
A09AA02
ATC
multienzymes (lipase, protease etc.)
133.3
323.0
426
53
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
323.0
688
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
141.5
323.0
416
48
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
+∞
323.0
581
*
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
763
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
1421.6
323.0
372
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
238.0
323.0
392
26
A03FA01
ATC
metoclopramide; systemic, rectal
29.1
323.0
676
602
A04AA02
ATC
granisetron; systemic, transdermal
1718.0
323.0
419
*
Z51.5
ICD-10 Finland
Palliative care
50.6
311.9
377
114
JLC30
NOMESCO Finland
Pancreatoduodenectomy
957.5
302.8
283
*
N02AA05
ATC
oxycodone; systemic
16.5
302.2
557
666
L01BC06
ATC
capecitabine; oral
+∞
290.3
265
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
1637.4
269.7
251
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
232.0
214
*
C25.1
ICD-10 Finland
Malignant neoplasm: Body of pancreas
+∞
212.8
197
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
205.0
190
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
38.5
195.2
250
84
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
194.9
181
*
UJK02
NOMESCO Finland
ERCP
33.9
188.2
249
95
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
183.7
178.9
183
12
K83.1
ICD-10 Finland
Obstruction of bile duct
83.0
177.3
197
29
8140/3-C25.0
ICD-O-3
Adenocarcinoma, NOS, of head of pancreas
+∞
176.0
164
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
123.4
173.5
184
18
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
53.0
166.4
199
46
JN4BD
NOMESCO Finland
Extensive body CT
15.3
164.5
288
251
A04AA01
ATC
ondansetron; systemic, rectal
34.2
157.9
208
75
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
+∞
151.8
142
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
145.2
136
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
21.2
135.6
206
119
JN4AD
NOMESCO Finland
Body CT examination
18.1
132.7
214
146
8500/3-C25.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of pancreas, NOS
+∞
129.9
122
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
42.9
129.1
161
44
JN4CD
NOMESCO Finland
Very extensive body CT
27.3
121.0
169
73
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.2
117.7
478
1453
C25.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of pancreas
+∞
109.3
103
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
578.8
107.7
105
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
55.3
107.1
127
26
JAH01
NOMESCO Finland
Laparoscopy
18.8
105.9
167
104
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
34.5
103.9
136
45
R4190
NOMESCO Finland
Nutritional therapy
27.9
101.8
141
58
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
11.5
101.4
200
210
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
99.5
94
*
L03AA02
ATC
filgrastim; parenteral
117.5
99.0
106
10
TPX10
NOMESCO Finland
Implantation of vascular injection port
23.2
97.1
142
70
WZC30
NOMESCO Finland
Teaching
6.9
95.0
263
481
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
28.7
92.6
127
50
D76
ICPC
Malignant neoplasm pancreas
+∞
92.0
87
*
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
59.2
87.0
102
19
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
25.1
85.0
121
54
A06AH03
ATC
naloxegol; oral
136.8
83.3
88
7
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
80.2
76
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
79.1
75
*
L03AA13
ATC
pegfilgrastim; parenteral
803.9
77.3
75
*
B01AB10
ATC
tinzaparin; parenteral
9.3
75.3
165
205
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.0
70.4
255
627
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
154.2
68.8
72
5
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
68.5
65
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.6
66.9
167
254
8500/3-C25.0
ICD-O-3
Infiltrating duct carcinoma, NOS, of head of pancreas
+∞
66.3
63
*
8140/3-C25.2
ICD-O-3
Adenocarcinoma, NOS, of tail of pancreas
+∞
66.3
63
*
JDE00
NOMESCO Finland
Gastrojejunostomy
678.0
65.6
64
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.1
64.6
192
371
R50.9
ICD-10 Finland
Fever, unspecified
4.5
64.1
260
711
WW500
NOMESCO Finland
Blood transfusion
14.4
61.2
106
81
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
219.1
60.7
62
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.8
60.1
222
549
JL1AT
NOMESCO Finland
Biopsy of pancreas with ultrasound guidance
+∞
60.0
57
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
60.0
57
*
B01AB05
ATC
enoxaparin; parenteral
3.1
59.4
434
1910
C25
ICD-10 Finland
Malignant neoplasm of pancreas
+∞
58.9
56
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
10.3
56.0
114
122
JLC10
NOMESCO Finland
Distal pancreatectomy
296.4
55.7
56
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
55.6
53.4
63
12
K83.0
ICD-10 Finland
Cholangitis
18.3
52.9
83
49
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
22.6
52.1
76
36
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
521.6
50.9
50
*
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
82.8
49.4
55
7
8140/3-C25.1
ICD-O-3
Adenocarcinoma, NOS, of body of pancreas
+∞
49.3
47
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
92.9
48.3
53
6
JMA10
NOMESCO Finland
Transabdominal total splenectomy
64.3
47.7
55
9
A04AD12
ATC
aprepitant; systemic
488.6
47.7
47
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
170.9
47.2
49
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
47.2
45
*
PHN73
NOMESCO Finland
Reconstruction of superior mesenteric or portal vein
466.7
45.6
45
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.6
44.4
169
422
JAH00
NOMESCO Finland
Laparotomy
10.4
43.4
87
90
R18
ICD-10 Finland
Ascites
16.1
43.3
71
47
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
41.4
302
1268
191
Kela drug reimbursment
Erlotinib
+∞
40.9
39
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.7
40.0
145
343
A98
ICPC
Health maint/preventive medicine
0.4
39.3
637
8381
C61
ICD-10 Finland
Malignant neoplasm of prostate
207.5
39.1
40
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
38.8
37
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
38.0
212
731
XX3DW
NOMESCO Finland
Time consuming IT work
5.7
37.8
115
223
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
37.7
36
*
J01MA12
ATC
levofloxacin; systemic
2.9
37.7
276
1150
TPH07
NOMESCO Finland
Cathetrisation of artery
3.7
37.2
178
543
WF002
NOMESCO Finland
Radical radiotherapy
85.2
37.1
41
5
A02BC02
ATC
pantoprazole; systemic
2.3
34.8
728
5169
A79
ICPC
Malignancy NOS
+∞
34.6
33
*
1CD01
NOMESCO Finland
NA
+∞
34.6
33
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
17.4
33.5
53
32
ZX120
NOMESCO Finland
Intravenous
4.0
33.3
142
390
N02AX02
ATC
tramadol; systemic, rectal
2.2
33.1
508
3097
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.3
32.7
104
212
A10AE04
ATC
insulin glargine; parenteral
3.4
32.6
177
592
L01XE03
ATC
[U] erlotinib; oral
+∞
32.5
31
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
31.4
30
*
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
34.6
31.1
40
12
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
321.8
31.0
31
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.6
30.7
68
84
JLC40
NOMESCO Finland
Total pancreatoduodenectomy
+∞
30.3
29
*
A06AD11
ATC
lactulose; oral
2.7
29.9
242
1051
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
109.8
29.8
32
*
115
Kela drug reimbursment
Breast cancer
+∞
29.3
28
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
10.0
29.2
59
62
WX402
NOMESCO Finland
General anaesthesia
3.1
28.1
173
632
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
27.9
214
897
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
36.1
27.6
35
10
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
9.1
27.3
58
67
WF004
NOMESCO Finland
Palliative radiotherapy
277.6
26.8
27
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
18.8
26.3
40
22
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
37.8
26.3
33
9
N02AA01
ATC
morphine; systemic, rectal
20.2
26.2
39
20
1570A
ICD-9 Finland
Malignant neoplasm of pancreas, Head of pancreas
+∞
26.1
25
*
WX004
NOMESCO Finland
Patient-controlled sedation
30.9
25.1
33
11
116
Kela drug reimbursment
Prostate cancer
+∞
25.1
24
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
25.1
236
1104
SPAT1109
SPAT
Analgesia with portable analgesic pump
24.1
24.9
35
15
ZX122
NOMESCO Finland
Intra-arterial
25.0
24.5
34
14
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
24.4
371
2169
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
24.3
278
1434
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
21.9
23.5
34
16
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
29.0
23.2
31
11
JL2AT
NOMESCO Finland
Cytology of pancreas with ultrasound guidance
+∞
23.0
22
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.9
22.9
77
167
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
85.3
22.7
25
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
85.3
22.7
25
*
N05BA06
ATC
lorazepam; systemic, sublingual
4.0
22.7
96
260
PJA12
NOMESCO Finland
Sentinel node biopsy
234.7
22.7
23
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
21.9
22.2
32
15
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
21.9
21
*
TJA10
NOMESCO Finland
Laparocentesis
+∞
21.9
21
*
K85.8
ICD-10 Finland
Other acute pancreatitis
22.8
21.8
31
14
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
224.3
21.7
22
*
JLA00
NOMESCO Finland
Exploration of pancreas
+∞
20.9
20
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.7
20.4
91
259
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
58.7
20.0
23
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
19.8
19
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
19.8
19
*
B01AB04
ATC
dalteparin; parenteral
3.9
19.8
85
234
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
10.1
19.2
38
39
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
23.0
19.1
27
12
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
10.3
19.0
37
37
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
18.8
18
*
JLA10
NOMESCO Finland
Biopsy of pancreas
+∞
18.8
18
*
K86.1
ICD-10 Finland
Other chronic pancreatitis
12.6
18.2
32
26
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
17.8
17
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
182.8
17.6
18
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.5
17.3
123
2375
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
64.4
16.8
19
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
35.6
16.7
21
6
JLD12
NOMESCO Finland
Endoscopic drainage of pancreatic pseudocyst
91.5
16.6
18
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
91.5
16.6
18
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
172.5
16.5
17
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.2
16.3
44
74
N05AD01
ATC
haloperidol; systemic
4.2
16.3
63
158
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.2
16.0
61
151
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
15.8
354
2306
ZX121
NOMESCO Finland
Central venous catheter
60.9
15.8
18
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.7
328
2088
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
15.7
15
*
JLC11
NOMESCO Finland
Laparoscopic distal pancreatectomy
+∞
15.7
15
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
162.2
15.5
16
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
162.2
15.5
16
*
A41.8
ICD-10 Finland
Other specified sepsis
6.1
15.2
41
69
N06DX01
ATC
memantine; oral
0.1
15.1
7
561
WX002
NOMESCO Finland
Sedation and analgesia
2.0
14.9
233
1333
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.5
14.8
101
1994
C25.7
ICD-10 Finland
Malignant neoplasm: Other parts of pancreas
+∞
14.6
14
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
14.2
139
652
J94.8
ICD-10 Finland
Other specified pleural conditions
6.8
14.1
35
53
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
13.9
179
948
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.5
13.9
130
2317
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.4
13.9
50
118
WF003
NOMESCO Finland
Adjuvant radiotherapy
54.0
13.8
16
*
C10AA05
ATC
atorvastatin; oral
0.6
13.8
225
3431
C10AA07
ATC
rosuvastatin; oral
0.5
13.7
96
1879
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
13.6
59
165
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
13.6
13
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
13.6
13
*
JFA65
NOMESCO Finland
Endoscopic insertion of ileum stent
+∞
13.6
13
*
TPX15
NOMESCO Finland
Removal of vascular injection port
26.1
13.4
18
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.3
461
3374
P20
ICPC
Memory disturbance
0.3
13.2
38
1054
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
6.0
12.9
35
60
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.1
12.9
8
527
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
5.1
12.7
39
78
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.6
12.6
189
2961
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
12.5
12
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
12.5
12
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
12.5
12
*
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
12.5
12
*
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
12.5
12
*
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
24.6
12.5
17
7
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
131.4
12.5
13
*
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
38.0
12.2
15
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
27.0
12.1
16
6
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
27.0
12.1
16
6
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
47.2
11.9
14
*
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
11.9
359
4783
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.2
11.9
28
40
M25.5
ICD-10 Finland
Pain in joint
0.5
11.6
87
1673
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
0.4
11.6
39
1011
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
10.2
11.5
22
22
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
11.5
11
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
11.5
11
*
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
11.5
11
*
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
+∞
11.5
11
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
11.5
11
*
C24.1
ICD-10 Finland
Malignant neoplasm: Ampulla of Vater
+∞
11.5
11
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
11.5
11
*
L02BA01
ATC
tamoxifen; oral
+∞
11.5
11
*
V03AF03
ATC
calcium folinate; systemic
121.2
11.4
12
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
11.4
91
384
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.5
11.4
124
2129
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
35.4
11.3
14
*
H25.1
ICD-10 Finland
Senile nuclear cataract
0.6
11.2
152
2456
WX610
NOMESCO Finland
Patient controlled analgesia
25.3
11.2
15
6
WX892
NOMESCO Finland
Monitored bed care
2.4
11.1
98
436
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
0.6
11.1
219
3224
SPAT1053
SPAT
Memory test
0.4
10.9
65
1358
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.5
10.8
37
84
C10AX09
ATC
ezetimibe; oral
0.3
10.6
28
808
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
60.6
10.6
12
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.4
10.6
31
59
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
10.6
53
1173
A21
ICPC
Risk factor for malignancy
111.0
10.4
11
*
JDE01
NOMESCO Finland
Laparoscopic gastroenterostomy
111.0
10.4
11
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
10.4
10
*
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
+∞
10.4
10
*
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
10.4
10
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
10.4
10
*
JDH35
NOMESCO Finland
Endoscopic insertion of duodenal stent
+∞
10.4
10
*
325
Kela drug reimbursment
Erlotinib
+∞
10.4
10
*
L02BB03
ATC
bicalutamide; oral
+∞
10.4
10
*
JKD00
NOMESCO Finland
Anastomosis of gallbladder to jejunum
+∞
10.4
10
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
10.4
10
*
TJA40
NOMESCO Finland
Percutaneous local drainage of peritoneal cavity
+∞
10.4
10
*
L02BG04
ATC
letrozole; oral
32.8
10.3
13
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.4
10.3
48
144
WX600
NOMESCO Finland
Single shot through catheter
19.0
10.3
15
8
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
11.4
10.1
18
16
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
8.5
10.1
21
25
I50.9
ICD-10 Finland
Heart failure, unspecified
0.5
10.0
69
1368
L02AE02
ATC
leuprorelin; implant, parenteral
20.2
9.8
14
7
SAA02
NOMESCO Finland
Basic examination of mouth
0.6
9.7
304
4075
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.9
9.6
21
27
WX320
NOMESCO Finland
Spinalanesthesy
0.5
9.6
89
1610
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.3
9.6
28
54
WX882
NOMESCO Finland
High dependency care
3.7
9.5
40
111
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.9
9.4
56
200
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
100.9
9.4
10
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
30.3
9.4
12
*
KA1FN
NOMESCO Finland
Isotope renography
30.3
9.4
12
*
YJ1CD
NOMESCO Finland
Very extensive CT examination of abdomen for dose design of radiotherapy
+∞
9.4
9
*
PHN72
NOMESCO Finland
Plastic repair of superior mesenteric or portal vein
+∞
9.4
9
*
D13
ICPC
Jaundice
+∞
9.4
9
*
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
+∞
9.4
9
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
9.4
9
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
9.4
9
*
6706
FHL
Pancreatic homeectomy (eg Whipple)
+∞
9.4
9
*
F03
ICD-10 Finland
Unspecified dementia
0.1
9.3
5
364
I48
ICD-10 Finland
Atrial fibrillation and flutter
0.6
9.3
141
2231
R83
ICPC
Respiratory infection other
0.4
9.3
37
900
K86.3
ICD-10 Finland
Pseudocyst of pancreas
10.8
9.3
17
16
Z01.2
ICD-10 Finland
Dental examination
0.6
9.3
152
2362
JKA20
NOMESCO Finland
Cholecystectomy
3.3
9.2
45
141
M79.6
ICD-10 Finland
Pain in limb
0.6
9.2
152
2356
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
10.1
9.0
17
17
K31.5
ICD-10 Finland
Obstruction of duodenum
37.0
9.0
11
*
WX704
NOMESCO Finland
Intubation
2.5
9.0
70
291
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.5
8.9
30
68
I81
ICD-10 Finland
Portal vein thrombosis
10.8
8.8
16
15
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
10.8
8.8
16
15
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.0
8.8
23
39
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.6
8.7
128
2047
K02.1
ICD-10 Finland
Caries of dentine
0.6
8.7
257
3512
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
0.6
8.6
133
2097
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
0.4
8.5
41
928
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
8.5
47
1011
R11
ICD-10 Finland
Nausea and vomiting
2.2
8.5
86
409
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.5
8.5
65
270
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
27.7
8.5
11
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
20.2
8.5
12
6
G04BD12
ATC
mirabegron; oral
0.3
8.5
23
655
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
8.4
137
786
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
0.6
8.4
162
2427
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
8.3
8
*
8500/3-C25.1
ICD-O-3
Infiltrating duct carcinoma, NOS, of body of pancreas
+∞
8.3
8
*
1571A
ICD-9 Finland
Malignant neoplasm of pancreas, Body of pancreas
+∞
8.3
8
*
PHC71
NOMESCO Finland
Suture of mesenteric or portal vein
+∞
8.3
8
*
R5140
NOMESCO Finland
Monitoring the use of the aid
0.3
8.3
21
622
K86.8
ICD-10 Finland
Other specified diseases of pancreas
10.8
8.3
15
14
L03
ICPC
Low back symptom/complaint
0.5
8.3
84
1485
B01AC04
ATC
clopidogrel; oral
0.5
8.2
79
1418
EB1AA
NOMESCO Finland
Tooth X-ray examination
0.7
8.1
272
3633
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
33.6
8.1
10
*
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
33.6
8.1
10
*
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
17.3
8.1
12
7
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
8.1
58
231
C10AC01
ATC
colestyramine; oral
3.4
8.0
37
112
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
0.3
7.9
13
477
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
0.3
7.8
20
588
R4110
NOMESCO Finland
Physiotherapy
1.6
7.8
240
1660
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.9
7.7
45
161
207
Kela drug reimbursment
Chronic arrhythmias
0.5
7.6
66
1224
HAB40
NOMESCO Finland
Wedge excision of mammary gland
11.9
7.6
13
11
R03AC02
ATC
salbutamol; inhalant
0.7
7.6
287
3760
SPAT1262
SPAT
Handing over of treatment supplies
1.6
7.6
200
1329
L13
ICPC
Hip symptom/complaint
0.5
7.5
58
1117
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.8
7.5
45
164
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.6
7.5
150
2237
I10
ICD-10 Finland
Essential (primary) hypertension
0.7
7.5
466
5603
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
80.6
7.4
8
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
80.6
7.4
8
*
E14.8
ICD-10 Finland
Unspecified diabetes mellitus, with unspecified complications
13.5
7.4
12
9
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
0.6
7.4
91
1526
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
7.3
7
*
8500/3-C25.2
ICD-O-3
Infiltrating duct carcinoma, NOS, of tail of pancreas
+∞
7.3
7
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
Y77
ICPC
Malignant neoplasm prostate
+∞
7.3
7
*
L01BC04
ATC
carmofur; oral
+∞
7.3
7
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
7.3
7
*
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
+∞
7.3
7
*
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
+∞
7.3
7
*
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
+∞
7.3
7
*
C25.3
ICD-10 Finland
Malignant neoplasm: Pancreatic duct
+∞
7.3
7
*
L15
ICPC
Knee symptom/complaint
0.5
7.2
75
1323
N06DA03
ATC
rivastigmine; oral, transdermal
0.2
7.2
5
304
HA1AA
NOMESCO Finland
X-ray mammography
3.7
7.2
29
79
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
20.2
7.1
10
5
N02AA03
ATC
hydromorphone; systemic, rectal
20.2
7.1
10
5
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.4
7.1
59
256
WX100
NOMESCO Finland
Conjunctival surface anesthesia
0.5
7.1
41
869
N05BA04
ATC
oxazepam; oral
1.6
7.1
230
1602
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.3
7.0
11
409
M70.6
ICD-10 Finland
Trochanteric bursitis
0.4
7.0
34
767
WX725
NOMESCO Finland
Noninvasive ventilation
2.6
7.0
49
196
M48.0
ICD-10 Finland
Spinal stenosis
0.5
6.9
48
949
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
0.7
6.8
219
2973
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
6.8
271
1979
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
6.1
6.8
17
28
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
0.5
6.8
46
919
XF612
NOMESCO Finland
Measurement of central venous pressure
16.8
6.7
10
6
AA1AD
NOMESCO Finland
CT of head and brain
0.6
6.7
127
1923
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
6.7
131
1968
R05
ICPC
Cough
0.6
6.7
81
1367
JFC00
NOMESCO Finland
Entero-enterostomy
22.7
6.7
9
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.4
6.7
56
245
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
0.6
6.6
82
1378
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
6.5
6.6
16
25
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.6
6.6
28
80
SPAT1255
SPAT
Intravenous administration of medicine
2.1
6.6
69
337
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.7
6.6
42
157
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.7
6.6
202
2770
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
0.4
6.6
35
761
SFA10
NOMESCO Finland
Fillning on one surface of tooth
0.7
6.6
252
3313
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.4
6.6
31
706
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
10.1
6.5
12
12
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
0.4
6.5
25
616
D70.89
ICD-10 Finland
Neutropenic splenomegaly
6.9
6.5
15
22
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
0.0
6.5
*
165
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.0
6.5
35
120
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
3.9
6.5
25
66
N05AX08
ATC
risperidone; systemic
0.4
6.5
19
523
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
70.2
6.4
7
*
K75.0
ICD-10 Finland
Abscess of liver
14.4
6.4
10
7
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
6.0
6.3
16
27
2390A
ICD-9 Finland
Neoplasm of unspecified nature, Digestive system
11.1
6.3
11
10
B01AF02
ATC
apixaban; oral
0.4
6.3
33
719
R93.3
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of digestive tract
18.1
6.3
9
5
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
+∞
6.3
6
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
6.3
6
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
6.3
6
*
1579X
ICD-9 Finland
Malignant neoplasm of pancreas, Pancreas, part unspecified
+∞
6.3
6
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
+∞
6.3
6
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
6.3
6
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
6.3
6
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
6.3
6
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
6.3
6
*
NK6LA
NOMESCO Finland
Bone and joint kinetic X-ray examination
+∞
6.3
6
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
+∞
6.3
6
*
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.2
374
2950
RD210
NOMESCO Finland
NA
4.8
6.2
19
40
A10AE05
ATC
insulin detemir; parenteral
2.2
6.2
61
288
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
26.8
6.2
8
*
H26.4
ICD-10 Finland
After-cataract
0.4
6.2
31
690
CJB10
NOMESCO Finland
Laser discission of secondary cataract
0.4
6.2
26
618
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.1
249
1821
DFF00
NOMESCO Finland
Pure tone audiometry
0.4
6.1
21
542
SDA02
NOMESCO Finland
Parodonthologic therapy
0.6
6.1
129
1908
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
12.6
6.1
10
8
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.6
6.0
143
2068

Mortality – FinRegistry

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This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

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Index endpoint: C3_PANCREAS_ADENO_DUCTAL_EXALLC – Adenocarcinoma and ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

GWS hits: 3

This endpoint is excluded (different definition than used in FinnGen).