Risteys · M13_ENTEROARTHR

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M07.4, M07.4K50.9, M07.5, M07.5K51.9, M07.6* Hospital discharge: ICD-9 — 7113 Cause of death: ICD-10 — M07.4, M07.4K50.9, M07.5, M07.5K51.9, M07.6* Cause of death: ICD-9 — 7113 2 out of 7 registries used, show all original rules.	892
4. Check minimum number of events None	892
5. Include endpoints None	892
6. Filter based on genotype QC (FinnGen only)	892

	All	Female	Male
Number of individuals
Whole population	3845	2119	1711
Only index persons	3646	2038	1608
Unadjusted period prevalence (%)
Whole population	0.05	0.06	0.05
Only index persons	0.07	0.07	0.06
Median age at first event (years)
Whole population	44.81	45.37	44.02
Only index persons	44.26	44.98	43.36

	All	Female	Male
Number of individuals	892	555	337
Unadjusted period prevalence (%)	0.17	0.19	0.15
Median age at first event (years)	44.96	43.65	47.12

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
811: Matched controls
8109

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M07.5*K51.9

ICD-10 Finland

Arthropathy in ulcerative colitis

+∞

323.0

368

L04AX03

ATC

methotrexate; systemic (immunosuppressants)

69.1

323.0

370

L04AX01

ATC

azathioprine; systemic

62.6

323.0

405

127

K51.9

ICD-10 Finland

Ulcerative colitis, unspecified

64.9

323.0

373

105

208

Kela drug reimbursment

Ulcerative colitis and Crohn's disease

140.9

323.0

614

175

A07EC02

ATC

mesalazine; oral, rectal

84.7

323.0

556

203

A07EC01

ATC

sulfasalazine; oral, rectal

151.1

323.0

515

M07.4*K50.9

ICD-10 Finland

Arthropathy in Crohn's disease [regional enteritis]

+∞

311.1

278

202

Kela drug reimbursment

Connective tissue diseases, rheumatoid arthritis and comparable disease

50.2

297.7

362

128

UJF32

NOMESCO Finland

Coloscopy

19.1

295.5

578

932

K51.5

ICD-10 Finland

Left sided colitis

51.4

267.9

323

103

A07EA06

ATC

budesonide; oral, local oral

49.2

252.4

307

H02AB06

ATC

prednisolone; systemic

14.9

234.0

682

2125

K50.9

ICD-10 Finland

Crohn disease, unspecified

115.7

231.2

244

K50.8

ICD-10 Finland

Other Crohn disease

99.1

226.8

244

A07EA02

ATC

hydrocortisone; rectal

48.7

191.0

232

NK4XE

NOMESCO Finland

Joint ultrasound examination not elsewhere classified

51.5

189.9

228

K50.1

ICD-10 Finland

Crohn disease of large intestine

83.1

181.7

201

TNX10

NOMESCO Finland

Arthrocentesis, unspecified region, unspecified region

86.9

180.1

198

UJF30

NOMESCO Finland

Ileoscopy through colon

16.3

176.7

309

294

K51.3

ICD-10 Finland

Ulcerative (chronic) rectosigmoiditis

45.6

167.3

206

L04AB04

ATC

adalimumab; parenteral

96.6

166.8

181

L01BA01

ATC

methotrexate; systemic (folic acid analog.)

161.3

162.3

167

K50.0

ICD-10 Finland

Crohn disease of small intestine

60.7

158.1

184

M07.5

ICD-10 Finland

Arthropathy in ulcerative colitis

1824.3

157.6

148

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

8.3

157.5

465

1135

M13.9

ICD-10 Finland

Arthritis, unspecified

39.7

128.5

163

K51.8

ICD-10 Finland

Other ulcerative colitis

51.0

128.1

154

M07.4

ICD-10 Finland

Arthropathy in Crohn disease [regional enteritis]

+∞

127.5

119

326

Kela drug reimbursment

Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)

101.1

124.6

135

K51.1

ICD-10 Finland

Ulcerative (chronic) ileocolitis

53.7

122.6

146

M07.3*L40.5

ICD-10 Finland

Other psoriatic arthropathies

1322.3

120.0

114

313

Kela drug reimbursment

Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)

83.3

114.4

127

H02AB07

ATC

prednisone; oral

8.5

113.0

282

479

281

Kela drug reimbursment

Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab

89.2

110.9

122

J01MA02

ATC

ciprofloxacin; systemic

5.2

104.3

482

1773

P01BA02

ATC

hydroxychloroquine; oral

19.2

92.5

145

N02AX02

ATC

tramadol; systemic, rectal

4.7

91.4

448

1673

M25.5

ICD-10 Finland

Pain in joint

5.9

89.9

302

740

K51.0

ICD-10 Finland

Ulcerative (chronic) pancolitis

54.6

88.5

105

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

5.1

86.8

350

1050

UJF45

NOMESCO Finland

Flexible sigmoidoscopy with biopsy

9.3

85.8

193

263

L88

ICPC

Rheumatoid/seropositive arthritis

53.5

83.2

L01BB02

ATC

mercaptopurine; oral

47.4

82.1

100

ZX120

NOMESCO Finland

Intravenous

8.4

80.5

194

294

K51.2

ICD-10 Finland

Ulcerative (chronic) proctitis

28.4

79.4

109

GD1AA

NOMESCO Finland

Thorax X-ray examination

4.2

78.7

434

1734

P01AB01

ATC

metronidazole; oral, rectal

4.1

77.1

469

2034

M05.8

ICD-10 Finland

Other seropositive rheumatoid arthritis

+∞

74.1

M17.1

ICD-10 Finland

Other primary gonarthrosis

15.2

69.1

118

M45

ICD-10 Finland

Ankylosing spondylitis

21.2

67.4

101

L40.5

ICD-10 Finland

Arthropathic psoriasis

105.9

62.9

UJF92

NOMESCO Finland

Capsular endoscopy

28.7

60.9

TPH04

NOMESCO Finland

Cathetrisation of vein

4.5

60.6

258

764

K52.9

ICD-10 Finland

Noninfective gastroenteritis and colitis, unspecified

14.4

59.3

103

A02BC02

ATC

pantoprazole; systemic

3.5

58.5

581

3411

M23.2

ICD-10 Finland

Derangement of meniscus due to old tear or injury

66.2

58.4

L04AA13

ATC

leflunomide; oral

313.6

58.0

K51

ICD-10 Finland

Ulcerative colitis

30.2

57.3

NG1AA

NOMESCO Finland

Knee X-ray examination without contrast

14.5

57.2

UJF14

NOMESCO Finland

Enteroscopy of ileoanal anastomosis

48.6

55.4

NGB20

NOMESCO Finland

Primary total prosthetic replacement of knee joint without patellar part

+∞

54.8

M07.3

ICD-10 Finland

Other psoriatic arthropathies

192.5

52.6

D94

ICPC

Chronic enteritis/ulcerative colitis

47.8

51.2

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

8.0

50.0

120

173

N02BE01

ATC

paracetamol; systemic, rectal

4.4

49.9

726

5344

L04AB06

ATC

golimumab; parenteral

66.7

48.9

A07EA01

ATC

prednisolone; rectal

55.6

48.4

4AA12

NOMESCO Finland

135.8

48.4

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

4.1

48.0

215

649

UJF12

NOMESCO Finland

Enteroscopy through intestinal stoma

108.7

47.3

M01AH01

ATC

celecoxib; oral (coxibs)

4.4

46.8

193

537

M19.0

ICD-10 Finland

Primary arthrosis of other joints

21.1

45.7

M06.9

ICD-10 Finland

Rheumatoid arthritis, unspecified

243.4

45.4

NF1AE

NOMESCO Finland

Hip joint ultrasound examination

29.9

45.4

WX002

NOMESCO Finland

Sedation and analgesia

4.0

45.3

212

661

N02AJ06

ATC

codeine and paracetamol; systemic

3.0

45.2

361

1694

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

2.9

45.0

413

2123

M01AH05

ATC

etoricoxib; oral

2.9

44.7

518

3080

NA6BG

NOMESCO Finland

Sacro-iliac joint MRI examination with high intensity magnet

19.8

43.5

M06.0

ICD-10 Finland

Seronegative rheumatoid arthritis

232.2

43.3

O99.6

ICD-10 Finland

Diseases of the digestive system complicating pregnancy, childbirth and the puerperium

26.4

42.5

M02.9

ICD-10 Finland

Reactive arthropathy, unspecified

154.8

42.2

M16.1

ICD-10 Finland

Other primary coxarthrosis

25.9

41.6

L04AC05

ATC

ustekinumab; parenteral

81.3

41.3

7113L

ICD-9 Finland

Arthropathy associated with infections, Postdysenteric arthropathy[ENTEROARTHRITIS, USEAT NIVELET]

+∞

41.0

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

6.8

40.8

108

178

JF1CG

NOMESCO Finland

Extensive MRI of small bowel

40.9

40.1

K50

ICD-10 Finland

Crohn disease [regional enteritis]

54.0

39.0

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

8.2

38.7

122

M46.1

ICD-10 Finland

Sacroiliitis, not elsewhere classified

28.5

37.7

JF1DG

NOMESCO Finland

Small bowel very extensive MRI with with high intensity magnet

86.3

37.2

NJ2MA

NOMESCO Finland

Measurement of mechanical axis of lower leg with X-ray

136.3

37.0

5568X

ICD-9 Finland

Idiopathic proctocolitis, Other ulcerative colitis

136.3

37.0

NH3EA

NOMESCO Finland

Feet X-ray examination with load

71.7

36.3

56310

ICD-8 Finland

Chronic enteritis and ulcerative colitis, Ulcerative colitis

68.1

34.3

A02BC01

ATC

omeprazole; systemic

2.9

34.1

253

1085

K52.88

ICD-10 Finland

Other specified noninfective gastroenteritis and colitis

12.8

34.0

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

2.6

33.7

332

1689

4AB02

NOMESCO Finland

43.1

33.4

M17.0

ICD-10 Finland

Primary gonarthrosis, bilateral

10.9

33.0

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

4.7

32.8

121

294

C10AC01

ATC

colestyramine; oral

9.5

31.5

NFB30

NOMESCO Finland

Primary total prosthetic replacement of hip joint not using cement

88.7

31.0

JN3AA

NOMESCO Finland

Abdominal X-ray examination without contrast

7.6

30.7

106

5561A

ICD-9 Finland

Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis

60.8

30.3

N03AX16

ATC

pregabalin; oral

3.0

30.3

206

826

A02BC03

ATC

lansoprazole; oral

2.8

30.2

247

1112

NGA30

NOMESCO Finland

Exploration of knee joint, arthroscopic

19.8

29.9

JN3BD

NOMESCO Finland

Extensive abdominal CT

4.0

29.2

128

365

A06AC01

ATC

ispaghula (psylla seeds); oral

2.9

29.1

217

920

A07DA03

ATC

loperamide; oral

8.7

29.1

NF1AA

NOMESCO Finland

Hip X-ray examination

8.6

28.9

M01AC06

ATC

meloxicam; systemic, rectal

2.5

28.8

301

1549

B01AB05

ATC

enoxaparin; parenteral

2.8

28.7

227

997

JFH30

NOMESCO Finland

Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy

50.6

28.6

5562A

ICD-9 Finland

Idiopathic proctocolitis, Ulcerative (chronic) proctitis

57.2

28.3

L04AB01

ATC

etanercept; parenteral

57.2

28.3

L40.0

ICD-10 Finland

Psoriasis vulgaris

7.4

28.2

101

D07AC01

ATC

betamethasone; topical

2.4

28.2

309

1630

L04AA01

ATC

[U] ciclosporin; systemic

23.3

28.1

A02BC05

ATC

esomeprazole; systemic

2.4

27.9

342

1908

TNH11

NOMESCO Finland

Injection of diagnostic or therapeutic substance in ankle joint or foot joint

150.1

27.8

TNX00

NOMESCO Finland

Puncture and needle biopsy of soft tissue, unspecified region

20.5

27.6

Z01.8

ICD-10 Finland

Other specified special examinations

2.9

27.6

202

841

H02AB09

ATC

hydrocortisone; systemic

11.5

27.2

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

4.7

27.1

227

JF1BD

NOMESCO Finland

Very extensive small bowel CT

64.3

27.1

J01DB01

ATC

cefalexin; oral

2.7

27.1

685

5411

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

4.4

27.0

105

267

NGD05

NOMESCO Finland

Partial excision of meniscus of knee, arthroscopic

7.5

26.5

H02AB04

ATC

methylprednisolone; systemic

3.3

26.4

146

501

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

3.3

26.3

144

491

NG1DA

NOMESCO Finland

X-ray of knees

74.9

25.9

NK6QA

NOMESCO Finland

Measurement of bone density from tow or more locations with X-ray

5.2

25.9

177

TND11

NOMESCO Finland

Injection of diagnostic or therapeutic substance in joint, wrist or hand

96.6

25.8

M01AH02

ATC

rofecoxib; oral

3.9

25.5

112

319

M46.9

ICD-10 Finland

Inflammatory spondylopathy, unspecified

21.5

25.4

M01CB01

ATC

sodium aurothiomalate; parenteral

+∞

25.1

E0000UV

ATC

2.2

24.8

351

2062

L04AD01

ATC

ciclosporin; systemic

10.2

24.6

WX320

NOMESCO Finland

Spinalanesthesy

3.1

24.1

149

552

M09.1*K50.9

ICD-10 Finland

Juvenile arthritis in Crohn's disease [regional enteritis]

+∞

24.1

WX408

NOMESCO Finland

General anesthesy, balanced

2.4

23.5

238

1179

K56.6

ICD-10 Finland

Other and unspecified intestinal obstruction

7.5

23.5

ND2BA

NOMESCO Finland

Hand and fingers extensive X-ray examination

16.8

23.4

1370

FHL

Colonoscopy, whole colon

25.5

23.2

M09.2*K51.9

ICD-10 Finland

Juvenile arthritis in ulcerative colitis

+∞

23.0

JFG00

NOMESCO Finland

Closure of loop enterostomy without resection

26.8

22.8

WX302

NOMESCO Finland

Thoracal epidural anesthesy

4.8

22.1

175

K60.3

ICD-10 Finland

Anal fistula

11.0

22.1

M074, L405

ICD-10 Finland

+∞

22.0

ND2DA

NOMESCO Finland

Bilateral hand X-ray examination

64.4

22.0

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

2.1

21.9

330

1963

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

3.8

21.7

279

R03AC02

ATC

salbutamol; inhalant

2.1

21.4

434

2914

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

3.2

21.3

124

439

NH3DA

NOMESCO Finland

Bilateral foot X-ray examination

34.8

21.2

K56.5

ICD-10 Finland

Intestinal adhesions [bands] with obstruction

12.4

21.2

D05AX02

ATC

calcipotriol; topical

6.6

21.0

S01XA20

ATC

artificial tears and other indifferent preparations; ophthalmic

2.1

20.9

317

1880

B03BA03

ATC

hydroxocobalamin; parenteral

5.9

20.8

106

N03AX12

ATC

gabapentin; oral

3.2

20.8

120

420

R4110

NOMESCO Finland

Physiotherapy

2.4

20.7

210

1034

M03BX02

ATC

tizanidine; oral

2.0

20.6

517

3756

L30.9

ICD-10 Finland

Dermatitis, unspecified

2.7

20.5

163

701

R50.9

ICD-10 Finland

Fever, unspecified

2.9

20.4

133

507

J01MA12

ATC

levofloxacin; systemic

2.7

20.3

157

664

H20.0

ICD-10 Finland

Acute and subacute iridocyclitis

5.8

20.0

107

M07.6

ICD-10 Finland

Other enteropathic arthropathies

+∞

19.9

TNG11

NOMESCO Finland

Injection of diagnostic or therapeutic substance in knee

+∞

19.9

JHA00

NOMESCO Finland

Anal or perianal incision

12.6

19.7

M17.5

ICD-10 Finland

Other secondary gonarthrosis

204.7

19.6

A07EC03

ATC

olsalazine; oral

41.2

19.6

601

Kela drug reimbursment

Severe malabsorption of nutrients, mainly fats

16.1

19.4

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

3.3

19.2

104

348

M01AX17

ATC

nimesulide; oral

2.5

19.1

174

806

H04.10

ICD-10 Finland

Dry eye syndrome

3.3

19.0

101

334

NHG80

NOMESCO Finland

Fusion of first tarsometatarsal joint

+∞

18.8

TNG10

NOMESCO Finland

Puncture of knee

71.6

18.8

J06.9

ICD-10 Finland

Acute upper respiratory infection, unspecified

2.0

18.8

383

2528

NH1AE

NOMESCO Finland

Ankle joint ultrasound examination

39.4

18.6

JFB00

NOMESCO Finland

Partial resection of small intestine

11.8

18.6

M16.0

ICD-10 Finland

Primary coxarthrosis, bilateral

15.5

18.6

WZB00

NOMESCO Finland

Telephone receipt or other advice

2.1

18.5

254

1426

K56.7

ICD-10 Finland

Ileus, unspecified

12.2

18.4

JH1CG

NOMESCO Finland

Extensive MRI of perianal area

30.8

18.4

K83.0

ICD-10 Finland

Cholangitis

11.0

18.1

ZX140

NOMESCO Finland

Intra articular

53.8

18.0

NH3BA

NOMESCO Finland

Foot and toes extensive X-ray examination

9.2

17.8

NGF15

NOMESCO Finland

Total synovectomy of knee, arthroscopic

+∞

17.8

M13.0

ICD-10 Finland

Polyarthritis, unspecified

97.2

17.6

M79.6

ICD-10 Finland

Pain in limb

2.1

17.6

258

1483

M00.9

ICD-10 Finland

Pyogenic arthritis, unspecified

183.8

17.6

L20

ICPC

Joint symptom/complaint NOS

7.0

17.5

NGF25

NOMESCO Finland

Operation for osteochondritis of knee, arthroscopic

12.3

17.4

M01AE02

ATC

naproxen; oral, rectal

1.9

17.3

451

3220

WX110

NOMESCO Finland

Local anesthesy

2.0

17.3

564

4369

J01FF01

ATC

clindamycin; systemic

2.2

17.1

221

1201

NF1DA

NOMESCO Finland

X-ray of hips

51.1

17.0

M75.1

ICD-10 Finland

Rotator cuff syndrome

2.4

16.7

163

777

WX404

NOMESCO Finland

Intravenous generell anesthesy

2.3

16.7

182

915

S18

ICPC

Laceration/cut

2.0

16.6

284

1731

JJ2AT

NOMESCO Finland

Biopsy of liver with ultrasound guidance

7.8

16.6

3042

Kela drug reimbursment

173.4

16.6

253

Kela drug reimbursment

173.4

16.6

K44.9

ICD-10 Finland

Diaphragmatic hernia without obstruction or gangrene

4.0

16.2

175

M05BA04

ATC

alendronic acid; oral

3.9

16.1

186

JF1AB

NOMESCO Finland

Passage examination of small bowell with X-ray

10.3

16.0

J01AA02

ATC

doxycycline; systemic

1.9

16.0

601

4822

M79.0

ICD-10 Finland

Rheumatism, unspecified

8.0

16.0

A02BA02

ATC

ranitidine; systemic

2.4

16.0

143

652

L15

ICPC

Knee symptom/complaint

2.6

15.9

129

556

D50.9

ICD-10 Finland

Iron deficiency anaemia, unspecified

3.6

15.9

215

NE1AA

NOMESCO Finland

Pelvis X-ray examination

5.4

15.8

JN3AD

NOMESCO Finland

Abdominal CT examination

3.6

15.8

211

WZA10

NOMESCO Finland

Long statement of health and health related matters

17.6

15.7

7113F

ICD-9 Finland

Arthropathy associated with infections, Postdysenteric arthropathy[ENTEROARTHRITIS, POLVI]

+∞

15.7

M06.8

ICD-10 Finland

Other specified rheumatoid arthritis

+∞

15.7

5551A

ICD-9 Finland

Regional enteritis, Large intestine

86.8

15.6

N05CF01

ATC

zopiclone; oral

2.0

15.6

236

1365

R2130

NOMESCO Finland

Counselling and guidance which enhance independent living

3.5

15.2

228

XX9XE

NOMESCO Finland

Other ultrasound examination

29.2

15.2

M23.9

ICD-10 Finland

Internal derangement of knee, unspecified

4.2

15.0

142

NK5AT

NOMESCO Finland

Joint injection with ultrasound guidance not elsewhere classified

57.8

14.8

JFA98

NOMESCO Finland

Other transluminal endoscopic local operation on intestine

7.7

14.8

M17.9

ICD-10 Finland

Gonarthrosis, unspecified

4.6

14.8

120

K43.9

ICD-10 Finland

Other and unspecified ventral hernia without obstruction or gangrene

5.3

14.8

D07AD01

ATC

clobetasol; topical

2.4

14.6

137

637

M05.9

ICD-10 Finland

Seropositive rheumatoid arthritis, unspecified

+∞

14.6

L04AB05

ATC

certolizumab pegol; parenteral

81.6

14.6

Z71.3

ICD-10 Finland

Dietary counselling and surveillance

4.1

14.6

151

M54.5

ICD-10 Finland

Low back pain

1.9

14.5

253

1540

D07AB02

ATC

hydrocortisone butyrate; topical

2.0

14.4

229

1345

M13.8

ICD-10 Finland

Other specified arthritis

43.3

14.1

M20.2

ICD-10 Finland

Hallux rigidus

43.3

14.1

M20.1

ICD-10 Finland

Hallux valgus (acquired)

7.4

14.1

B81

ICPC

Anaemia vit B12/folate deficiency

6.1

14.1

M15.9

ICD-10 Finland

Polyarthrosis, unspecified

7.7

14.0

5552A

ICD-9 Finland

Regional enteritis, Small intestine with large intestine

54.3

13.8

NG1AE

NOMESCO Finland

Knee joint ultrasound exmination

24.3

13.8

SAA01

NOMESCO Finland

Simple examination of mouth

1.8

13.8

567

4553

K92.1

ICD-10 Finland

Melaena

4.5

13.7

111

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

3.8

13.6

166

Z96.6

ICD-10 Finland

Presence of orthopaedic joint implants

76.4

13.6

56300

ICD-8 Finland

Chronic enteritis and ulcerative colitis, Regional enteritis

34.7

13.5

L04AA29

ATC

tofacitinib; oral

142.2

13.5

3005

Kela drug reimbursment

Tofacitinib

142.2

13.5

M20.4

ICD-10 Finland

Other hammer toe(s) (acquired)

18.6

13.4

JFF10

NOMESCO Finland

Loop enterostomy

26.2

13.4

JFH10

NOMESCO Finland

Total colectomy and ileostomy

26.2

13.4

Z93.2

ICD-10 Finland

Ileostomy status

21.6

13.4

A49.9

ICD-10 Finland

Bacterial infection, unspecified

3.0

13.3

270

J02AC01

ATC

fluconazole; systemic

1.8

13.3

328

2232

NA1EA

NOMESCO Finland

Cervical spine X-ray examination with flexion

14.1

13.3

M01AB55

ATC

diclofenac, combinations; oral

4.2

13.2

125

M02AA07

ATC

piroxicam; topical

1.9

13.2

240

1473

JFB20

NOMESCO Finland

Ileocaecal resection

15.4

13.1

NB1AE

NOMESCO Finland

Shoulder ultrasound examination

15.4

13.1

J01FA10

ATC

azithromycin; systemic

1.7

13.1

470

3582

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

1.9

13.1

260

1646

J01CA04

ATC

amoxicillin; systemic

1.9

13.0

645

5446

G56.0

ICD-10 Finland

Carpal tunnel syndrome

2.6

13.0

100

417

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

2.6

13.0

103

437

JAH00

NOMESCO Finland

Laparotomy

5.8

13.0

M54.9

ICD-10 Finland

Dorsalgia, unspecified

2.6

12.7

410

ZXA00

NOMESCO Finland

Right side

2.1

12.6

161

856

JX1LA

NOMESCO Finland

Kinetic X-ray of alimentary tract with pictures

71.0

12.6

M13.1

ICD-10 Finland

Monoarthritis, not elsewhere classified

71.0

12.6

AA1AD

NOMESCO Finland

CT of head and brain

2.1

12.6

153

797

M25.4

ICD-10 Finland

Effusion of joint

32.6

12.6

K61.0

ICD-10 Finland

Anal abscess

7.5

12.6

N06AX11

ATC

mirtazapine; oral

1.9

12.5

241

1500

N02AA05

ATC

oxycodone; systemic

2.7

12.5

348

6960A

ICD-9 Finland

Psoriasis and similar disorders, Psoriatic arthropathy

+∞

12.5

NHK30

NOMESCO Finland

Osteotomy or rotation osteotomy of first metatarsal or tarsal bone

+∞

12.5

M07.0*L40.5

ICD-10 Finland

Distal interphalangeal psoriatic arthropathy

+∞

12.5

TNB11

NOMESCO Finland

Injection of diagnostic or therapeutic substance in shoulder joint

+∞

12.5

R4120

NOMESCO Finland

Occupational therapy

3.7

12.4

153

SAA02

NOMESCO Finland

Basic examination of mouth

1.7

12.4

516

4079

E000001

ATC

2.0

12.4

176

982

M01AX01

ATC

nabumetone; oral

4.5

12.4

M01AH03

ATC

valdecoxib; oral

3.6

12.3

159

R06.0

ICD-10 Finland

Dyspnoea

2.1

12.3

159

851

NA6AA

NOMESCO Finland

Sacro-iliac joint X-ray examination

38.2

12.2

NH1AA

NOMESCO Finland

Ankle X-ray examination without contrast

3.6

12.1

161

DM1AA

NOMESCO Finland

Paranasal sinuses X-ray examination without contrast

4.6

12.1

NGF35

NOMESCO Finland

Plastic operation of joint cartilage of knee

18.4

12.1

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

3.3

12.1

189

S01BA04

ATC

prednisolone; ophthalmic (corticosteroids, plain)

7.7

12.0

SPAT1153

SPAT

Removal of sutures

1.9

12.0

198

1165

M22.4

ICD-10 Finland

Chondromalacia patellae

13.6

12.0

NH3FA

NOMESCO Finland

Weight-bearing X-ray of foot

47.4

11.9

WVA20

NOMESCO Finland

Medicine administration

6.0

11.9

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

2.6

11.8

354

JHD20

NOMESCO Finland

Incision of fistula-in-ano

10.7

11.8

NB1AA

NOMESCO Finland

Shoulder X-ray examination without contrast

4.0

11.6

120

JFH11

NOMESCO Finland

Laparoscopic colectomy

65.9

11.6

NG1CG

NOMESCO Finland

Knee and lower leg extensive MRI examination with high intensity magnet

19.2

11.6

GD1PA

NOMESCO Finland

X-ray examination of the lungs in one projection

3.1

11.6

221

D05AX52

ATC

calcipotriol, combinations; topical

3.7

11.6

146

SPAT1249

SPAT

Treatment-related counselling outside office

1.7

11.6

298

2032

C03CA01

ATC

furosemide; systemic

2.1

11.5

142

745

NHG77

NOMESCO Finland

Arthroplasty of interphalangeal tarsal joint(s)

+∞

11.5

7151F

ICD-9 Finland

Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]

+∞

11.5

JFA38

NOMESCO Finland

Endoscopic dilatation of small intestine

+∞

11.5

1220

FHL

Arthroscopy

6.5

11.5

TQW40

NOMESCO Finland

Remowal of suture of skin

3.4

11.5

169

NE1CG

NOMESCO Finland

Pelvic, hip and femur extensive MRI examination with high intensity magnet

8.0

11.4

3AC01

NOMESCO Finland

10.7

11.3

WZA90

NOMESCO Finland

Other doctors statement

2.0

11.3

173

988

NHU20

NOMESCO Finland

Removal of internal fixation device from ankle or foot

5.6

11.3

TNX33

NOMESCO Finland

Custom moulded cast, unspecified region

3.9

11.2

124

WX402

NOMESCO Finland

General anaesthesia

2.1

11.2

142

753

S97

ICPC

Chronic ulcer skin

4.3

11.2

100

N06AA09

ATC

amitriptyline; systemic

2.9

11.2

253

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

1.9

11.1

182

1067

ZXA05

NOMESCO Finland

Left side

2.1

11.1

143

765

WYA05

NOMESCO Finland

Emergency visit or other similar visit involving procedures

1.7

11.1

380

2804

S01CA02

ATC

prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

10.2

11.0

WZA00

NOMESCO Finland

Short statement of of health and health related matters

3.4

10.9

165

A05AA02

ATC

ursodeoxycholic acid; oral

5.5

10.8

S01BA01

ATC

dexamethasone; ophthalmic (corticosteroids, plain)

4.4

10.8

SAA03

NOMESCO Finland

Extended examination of mouth

1.7

10.8

310

2171

J45.9

ICD-10 Finland

Asthma, unspecified

2.1

10.7

127

655

R07.4

ICD-10 Finland

Chest pain, unspecified

1.9

10.7

174

1016

FB1BD

NOMESCO Finland

Extensive CT examination of arteria pulmonalis

3.1

10.7

204

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

2.7

10.7

298

J01FA06

ATC

roxithromycin; oral

1.7

10.6

300

2085

NG1EA

NOMESCO Finland

Knee X-ray examination with wrench

60.8

10.6

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

1.9

10.6

171

996

A07AA09

ATC

vancomycin; oral

10.2

10.5

Z50.1

ICD-10 Finland

Other physical therapy

3.9

10.5

111

A02BA04

ATC

nizatidine; systemic

3.1

10.5

187

L04AC10

ATC

secukinumab; parenteral

111.4

10.4

NHG26

NOMESCO Finland

Fusion between bones of ankle or ankle and foot

111.4

10.4

JFH20

NOMESCO Finland

Proctocolectomy and ileostomy

111.4

10.4

R06AE07

ATC

cetirizine; oral

1.7

10.4

333

2397

K51.4

ICD-10 Finland

Inflammatory polyps

+∞

10.4

L04AA17

ATC

[U] adalimumab; parenteral

+∞

10.4

M075, K509

ICD-10 Finland

+∞

10.4

NDG30

NOMESCO Finland

Fusion of wrist, total

+∞

10.4

M07.0

ICD-10 Finland

Distal interphalangeal psoriatic arthropathy

+∞

10.4

TNC11

NOMESCO Finland

Injection of diagnostic or therapeutic substance in elbow joint

+∞

10.4

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

4.4

10.4

M15.0

ICD-10 Finland

Primary generalized (osteo)arthrosis

16.3

10.4

SPAT1310

SPAT

Counselling related to known health issue

1.8

10.3

226

1456

R51.80

ICD-10 Finland

Headache

2.2

10.3

117

589

R11

ICD-10 Finland

Nausea and vomiting

2.8

10.3

243

JKE98

NOMESCO Finland

Other transduodenal endoscopic operation on bile duct or ampulla of Vater

6.8

10.3

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

3.2

10.2

173

DM1QA

NOMESCO Finland

Paranasal sinuses X-ray examination in one projection

3.3

10.2

157

D07XC01

ATC

betamethasone, combinations; topical

2.3

10.2

467

SFA10

NOMESCO Finland

Fillning on one surface of tooth

1.6

10.2

413

3160

EB1AA

NOMESCO Finland

Tooth X-ray examination

1.6

10.2

426

3287

D07AC13

ATC

mometasone; topical

1.8

10.1

220

1411

D07AB08

ATC

desonide; topical

2.3

10.1

425

H15.1

ICD-10 Finland

Episcleritis

8.6

10.1

X59

ICD-10 Finland

Exposure to unspecified factor

2.1

10.1

126

664

N06AX21

ATC

duloxetine; oral

2.5

10.1

351

JFA15

NOMESCO Finland

Endoscopic polypectomy in colon

4.1

10.0

J05AB11

ATC

valaciclovir; oral

2.2

10.0

109

541

K57.3

ICD-10 Finland

Diverticular disease of large intestine without perforation or abscess

2.2

10.0

102

491

M03BC01

ATC

orphenadrine (citrate); systemic

1.8

10.0

184

1119

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

2.5

9.9

324

A04.7

ICD-10 Finland

Enterocolitis due to Clostridium difficile

6.4

9.9

UJD02

NOMESCO Finland

Gastroscopy

3.6

9.9

128

NF1BA

NOMESCO Finland

Hip extensive X-ray examination

12.4

9.9

D64.9

ICD-10 Finland

Anaemia, unspecified

2.7

9.9

255

R10.1

ICD-10 Finland

Pain localized to upper abdomen

2.1

9.9

116

593

JHD33

NOMESCO Finland

Completing incision of fistula-in-ano

26.4

9.8

JFG40

NOMESCO Finland

Revision of enterostomy or colostomy without laparotomy

26.4

9.8

NG1BG

NOMESCO Finland

Knee and lower leg MRI examination with high intensity magnet

6.6

9.8

A07AA02

ATC

nystatin; oral

3.3

9.8

151

JGB50

NOMESCO Finland

Mucosal proctectomy and ileoanal anastomosis

55.7

9.7

56399

ICD-8 Finland

Chronic enteritis and ulcerative colitis, Other

55.7

9.7

M79.1

ICD-10 Finland

Myalgia

2.2

9.7

458

A03FA01

ATC

metoclopramide; systemic, rectal

1.9

9.6

157

914

Z01.0

ICD-10 Finland

Examination of eyes and vision

2.1

9.6

115

595

H20.1

ICD-10 Finland

Chronic iridocyclitis

8.5

9.6

NH1BG

NOMESCO Finland

Ankle and foot MRI examination with high intensity magnet

11.5

9.6

M10.9

ICD-10 Finland

Gout, unspecified

6.1

9.6

D05AX03

ATC

calcitriol; topical

9.2

9.6

UJF02

NOMESCO Finland

Peroral enteroscopy

15.2

9.5

M01AB05

ATC

diclofenac; systemic, rectal

1.6

9.5

486

3919

JFB33

NOMESCO Finland

Other resection comprising small intestine and colon

30.4

9.4

M075, K515

ICD-10 Finland

+∞

9.4

M01CB03

ATC

auranofin; oral

+∞

9.4

M075, L405

ICD-10 Finland

+∞

9.4

M02.1

ICD-10 Finland

Postdysenteric arthropathy

+∞

9.4

JFG50

NOMESCO Finland

Laparotomy with revision of enterostomy or colostomy

+∞

9.4

NGB40

NOMESCO Finland

Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis

+∞

9.4

72410

ICD-8 Finland

Internal derangement of joint, Other shoulder derangement

+∞

9.4

NDG60

NOMESCO Finland

Arthroplasty of first CMC joint

+∞

9.4

JF1CM

NOMESCO Finland

Small bowel extensive MRI with with high intensity magnet

+∞

9.4

M35.7

ICD-10 Finland

Hypermobility syndrome

12.5

9.4

N05BA04

ATC

oxazepam; oral

1.8

9.4

188

1173

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

2.3

9.3

394

J01DA01

ATC

[U] cefalexin; systemic

1.6

9.3

461

3677

RD210

NOMESCO Finland

5.8

9.3

M01AX05

ATC

glucosamine; oral

2.5

9.2

317

L12

ICPC

Hand/finger symptom/complaint

2.1

9.1

103

518

UJG02

NOMESCO Finland

Proctoscopy

5.2

9.1

NA2AA

NOMESCO Finland

Thoracal spine X-ray examination without contrast

6.4

9.1

J05AB01

ATC

aciclovir; systemic

1.8

9.1

161

962

M01AE03

ATC

ketoprofen; systemic, rectal

1.7

9.1

252

1727

SPAT1262

SPAT

Handing over of treatment supplies

2.0

9.1

128

706

K76.9

ICD-10 Finland

Liver disease, unspecified

7.2

9.1

SPAT1148

SPAT

Treatment of chronic ulcer or burn

2.3

9.1

386

S01FA04

ATC

cyclopentolate; ophthalmic

9.2

9.1

M04AA01

ATC

allopurinol; systemic

2.7

9.0

237

NFB40

NOMESCO Finland

Primary total prosthetic replacement of hip joint using hybrid technique

37.1

9.0

5550A

ICD-9 Finland

Regional enteritis, Small intestine

37.1

9.0

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

1.7

9.0

213

1394

G44.2

ICD-10 Finland

Tension-type headache

2.1

9.0

102

513

NE1BG

NOMESCO Finland

Pelvic, hip and femur MRI examination with high intensity magnet

6.2

9.0

T84.0

ICD-10 Finland

Mechanical complication of internal joint prosthesis

24.3

8.9

M81.9

ICD-10 Finland

Osteoporosis, unspecified

4.9

8.9

L16

ICPC

Ankle symptom/complaint

2.5

8.9

278

WW200

NOMESCO Finland

Immunization

4.4

8.9

KMAK

NOMESCO Finland

1.6

8.9

408

3182

A06AD11

ATC

lactulose; oral

2.3

8.8

372

L17

ICPC

Foot/toe symptom/complaint

1.8

8.8

154

917

SFA20

NOMESCO Finland

Filling on two surfaces of tooth

1.6

8.8

451

3605

M21.4

ICD-10 Finland

Flat foot [pes planus] (acquired)

8.7

8.8

SPAT1263

SPAT

Sampling

1.6

8.8

299

2158

NH1CG

NOMESCO Finland

Ankle and foot extensive MRI examination with high intensity magnet

10.9

8.8

L28

ICPC

Limited function/disability (L)

2.3

8.8

377

TJD00

NOMESCO Finland

Insertion of nasogastric or naso-gastroduodenal tube

7.3

8.8

K02.1

ICD-10 Finland

Caries of dentine

1.6

8.7

443

3532

XF603

NOMESCO Finland

Direct intraarterial blood pressure measurement

4.2

8.7

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

2.0

8.7

120

655

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

1.7

8.7

193

1238

J01FA09

ATC

clarithromycin; systemic

1.7

8.7

235

1594

JFH33

NOMESCO Finland

Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy

50.5

8.7

ACC51

NOMESCO Finland

Release of median nerve

2.9

8.7

183

R52.9

ICD-10 Finland

Pain, unspecified

2.6

8.6

257

Z03.89

ICD-10 Finland

Observation for other suspected diseases and conditions

2.2

8.6

437

M18.1

ICD-10 Finland

Other primary arthrosis of first carpometacarpal joint

27.8

8.5

B01AX06

ATC

[U] rivaroxaban; oral

27.8

8.5

M47.82

ICD-10 Finland

Other spondylosis, cervical region

4.4

8.5

SHB00

NOMESCO Finland

Prepation and fitting of bite rail to mouth

2.2

8.5

428

M19.1

ICD-10 Finland

Post-traumatic arthrosis of other joints

20.3

8.5

NG2AA

NOMESCO Finland

Patella X-ray examination

20.3

8.5

H20.9

ICD-10 Finland

Iridocyclitis, unspecified

7.5

8.5

E27.3

ICD-10 Finland

Drug-induced adrenocortical insufficiency

90.9

8.4

JL5BG

NOMESCO Finland

MRI examinaiton of bile and pancreas ducts with high intesity magnet

4.7

8.4

R01AD12

ATC

fluticasone furoate; nasal

1.6

8.3

237

1629

L04AA33

ATC

vedolizumab; parenteral

+∞

8.3

NH3AE

NOMESCO Finland

Feet ultrasound examination

+∞

8.3

M06

ICD-10 Finland

Other rheumatoid arthritis

+∞

8.3

7350A

ICD-9 Finland

Acquired deformities of toe, Hallux valgus (acquired)

+∞

8.3

M076, L405

ICD-10 Finland

+∞

8.3

M19.9

ICD-10 Finland

Arthrosis, unspecified

5.9

8.3

A01AB09

ATC

miconazole; local oral

2.5

8.3

269

R52.2

ICD-10 Finland

Other chronic pain

4.6

8.2

SPAT1325

SPAT

Vaccination

1.7

8.2

221

1496

R01AD09

ATC

mometasone; nasal

1.6

8.2

337

2544

K07.60

ICD-10 Finland

Snapping jaw

3.1

8.1

144

J18.9

ICD-10 Finland

Pneumonia, unspecified

1.8

8.1

140

830

JHD30

NOMESCO Finland

Incomplete incision of fistula-in-ano

33.7

8.1

M25.9

ICD-10 Finland

Joint disorder, unspecified

17.4

8.1

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

1.5

8.1

379

2946

WX290

NOMESCO Finland

Other blockade of nerve

1.5

8.1

352

2690

S01FA02

ATC

scopolamine; ophthalmic

10.2

8.0

Z93

ICD-10 Finland

Artificial opening status

22.3

8.0

F43.22

ICD-10 Finland

Adaptation disorder with mixed anxiety and depression

3.2

8.0

129

R4190

NOMESCO Finland

Nutritional therapy

3.5

8.0

102

A03CA02

ATC

clidinium and psycholeptics; oral

3.1

7.9

141

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

3.1

7.9

136

N05CF02

ATC

zolpidem; oral

1.8

7.9

136

804

L13

ICPC

Hip symptom/complaint

2.2

7.8

357

NA6CG

NOMESCO Finland

Sacro-iliac joint extensive MRI examination with high intensity magnet

10.9

7.8

M65.9

ICD-10 Finland

Synovitis and tenosynovitis, unspecified

4.9

7.8

M17

ICD-10 Finland

Gonarthrosis [arthrosis of knee]

2.9

7.8

159

WZC10

NOMESCO Finland

Extensive specialist consultion with written report

3.1

7.8

132

XA402

NOMESCO Finland

ENMG

6.5

7.7

NGF00

NOMESCO Finland

Excision of plica of synovy of knee

15.2

7.7

M06.4

ICD-10 Finland

Inflammatory polyarthropathy

45.4

7.7

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

1.9

7.7

119

675

E66.01

ICD-10 Finland

Obesity due to excess calories

2.5

7.7

247

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

2.4

7.6

256

107

Kela drug reimbursment

Pernicious anaemia

6.8

7.6

D11

ICPC

Diarrhoea

2.1

7.6

462

Z98.0

ICD-10 Finland

Intestinal bypass and anastomosis status

12.0

7.6

JHW96

NOMESCO Finland

Other operation on anus or perianal tissue

25.3

7.6

R02

ICPC

Shortness of breath/dyspnoea

2.2

7.6

348

SBA00

NOMESCO Finland

Microbiological examinations

4.6

7.4

6419

FHL

Other measure in this category

80.8

7.4

M17.4

ICD-10 Finland

Other secondary gonarthrosis, bilateral

80.8

7.4

M02.8

ICD-10 Finland

Other reactive arthropathies

80.8

7.4

NF2AT

NOMESCO Finland

Injection to hip joint with ultrasound guidance

80.8

7.4

M09AX01

ATC

hyaluronic acid; parenteral

7.7

7.4

R35

ICD-10 Finland

Polyuria

2.8

7.4

166

C05AA08

ATC

fluocortolone; rectal, topical

1.9

7.4

108

603

UKC02

NOMESCO Finland

Cystoscopy

2.0

7.4

477

K56.0

ICD-10 Finland

Paralytic ileus

8.5

7.3

M02AA10

ATC

ketoprofen; topical

2.0

7.3

100

544

F45.4

ICD-10 Finland

Persistent somatoform pain disorder

6.9

7.3

ZXM10

NOMESCO Finland

Intraoperative use of conventional X-ray imaging

3.2

7.3

121

M074, K508

ICD-10 Finland

+∞

7.3

M073, K519

ICD-10 Finland

+∞

7.3

M07.2*L40.5

ICD-10 Finland

Psoriatic spondylitis

+∞

7.3

291

Kela drug reimbursment

Tofacitinib

+∞

7.3

71239

ICD-8 Finland

Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD

+∞

7.3

212

Kela drug reimbursment

Gout

+∞

7.3

WX111

NOMESCO Finland

Local infiltration anesthesia

+∞

7.3

R03DC03

ATC

montelukast; oral

1.9

7.3

114

650

Y88.3

ICD-10 Finland

Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

6.3

7.3

QBB10

NOMESCO Finland

Major dressing of wound of skin of trunk

3.1

7.2

122

WZC30

NOMESCO Finland

Teaching

2.0

7.2

508

1300

FHL

Esophagogastroduodenoscopy (also includes staining)

7.4

7.2

JFG73

NOMESCO Finland

Excision of ileal pelvic pouch

30.3

7.2

M22.0

ICD-10 Finland

Recurrent dislocation of patella

30.3

7.2

4AA33

NOMESCO Finland

30.3

7.2

5560A

ICD-9 Finland

Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis

30.3

7.2

XF400

NOMESCO Finland

ECG with 12 standard connections

1.9

7.1

543

1490

FHL

Sigmoideoscopy (fiberscope)

20.2

7.1

D02AE01

ATC

carbamide; topical

2.5

7.1

219

NA2BG

NOMESCO Finland

Thoracal spine MRI examination with high intensity magnet

4.6

7.1

B01AF01

ATC

rivaroxaban; oral

2.8

7.1

168

203

Kela drug reimbursment

Chronic asthma and similar chronic obstructive pulmonary diseases

1.8

7.1

128

768

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

1.7

7.0

166

1077

L01

ICPC

Neck symptom/complaint

1.9

7.0

523

K59.1

ICD-10 Finland

Functional diarrhoea

2.9

7.0

147

M67.4

ICD-10 Finland

Ganglion

2.7

7.0

172

NHM20

NOMESCO Finland

Excision of synovial ganglion of ankle or foot

13.9

6.9

L52

ICD-10 Finland

Erythema nodosum

13.9

6.9

M81.4

ICD-10 Finland

Drug-induced osteoporosis

13.9

6.9

S29

ICPC

Skin symptom/complaint other

1.9

6.9

102

571

M54.4

ICD-10 Finland

Lumbago with sciatica

1.9

6.9

109

626

A02BX02

ATC

sucralfate; oral

3.6

6.8

E86

ICD-10 Finland

Volume depletion

5.1

6.8

Z04.9

ICD-10 Finland

Examination and observation for unspecified reason

3.1

6.8

116

JL5CG

NOMESCO Finland

Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet

9.4

6.8

L43.8

ICD-10 Finland

Other lichen planus

5.4

6.8

JAD30

NOMESCO Finland

Repair of incisional hernia using prosthetic material

6.2

6.8

L73.2

ICD-10 Finland

Hidradenitis suppurativa

6.2

6.8

D01AC20

ATC

imidazoles/triazoles in combination with corticosteroids; topical

1.7

6.8

161

1049

R21

ICD-10 Finland

Rash and other nonspecific skin eruption

2.9

6.8

138

I10

ICD-10 Finland

Essential (primary) hypertension

1.5

6.8

319

2449

N20.1

ICD-10 Finland

Calculus of ureter

3.3

6.8

100

L01BB01

ATC

40.4

6.8

NHG24

NOMESCO Finland

Fusion of subtalar joint and between bones of ankle

40.4

6.8

M18.0

ICD-10 Finland

Primary arthrosis of first carpometacarpal joints, bilateral

16.8

6.8

D50.0

ICD-10 Finland

Iron deficiency anaemia secondary to blood loss (chronic)

3.7

6.7

M23.8

ICD-10 Finland

Other internal derangements of knee

7.3

6.7

TPH20

NOMESCO Finland

Insertion of central venous catheter through subclavian or brachiocephalic vein

3.9

6.7

G47.3

ICD-10 Finland

Sleep apnoea

1.7

6.7

142

895

JN2CG

NOMESCO Finland

Extensive MRI examination of lower part of abdoment with high intensity magnet

5.0

6.7

9271

FHL

Hallux surgery

22.7

6.7

7200A

ICD-9 Finland

Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis

22.7

6.7

XJW99

NOMESCO Finland

Other investigative procedure on digestive system

22.7

6.7

SPAT1256

SPAT

Intramuscular and subcutaneous injection

1.5

6.6

274

2044

F32.11

ICD-10 Finland

Moderate depressive episode with somatic syndrome

3.6

6.6

EBA00

NOMESCO Finland

Extraction of tooth

1.6

6.6

229

1640

D01

ICPC

Abdominal pain/cramps general

2.1

6.6

352

M01AE52

ATC

naproxen and esomeprazole; oral

3.8

6.6

EBA05

NOMESCO Finland

Complicated extraction of tooth

1.7

6.5

137

861

Z87.1

ICD-10 Finland

Personal history of diseases of the digestive system

1.5

6.5

310

2385

5586X

ICD-9 Finland

Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]

70.4

6.4

NHG22

NOMESCO Finland

Fusion of subtalar joint

70.4

6.4

G56.2

ICD-10 Finland

Lesion of ulnar nerve

4.1

6.4

K07.65

ICD-10 Finland

Temporomandibular joint-pain-dysfunction syndrome

7.5

6.4

TJF80

NOMESCO Finland

Ostomy education

7.5

6.4

F43.29

ICD-10 Finland

Adaptation disorder UNS

3.7

6.4

Z71.8

ICD-10 Finland

Other specified counselling

1.6

6.4

170

1138

-69

ICPC

Other reason for encounter NEC

3.2

6.4

L90

ICPC

Osteoarthrosis of knee

5.0

6.4

A46

ICD-10 Finland

Erysipelas

2.0

6.4

400

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

2.1

6.4

372

M01AB01

ATC

indometacin; systemic, rectal

2.8

6.4

146

L98.4

ICD-10 Finland

Chronic ulcer of skin, not elsewhere classified

6.6

6.4

UJF34

NOMESCO Finland

Left colonoscopy

9.3

6.3

K58.0

ICD-10 Finland

Irritable bowel syndrome with diarrhoea

2.6

6.3

175

M87.0

ICD-10 Finland

Idiopathic aseptic necrosis of bone

18.2

6.3

7140B

ICD-9 Finland

Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]

+∞

6.3

M46.8

ICD-10 Finland

Other specified inflammatory spondylopathies

+∞

6.3

TND10

NOMESCO Finland

Joint puncture, wrist or finger joint

+∞

6.3

7177A

ICD-9 Finland

Internal derangement of knee, Chondromalacia of patella

+∞

6.3

M16.7

ICD-10 Finland

Other secondary coxarthrosis

+∞

6.3

H22.1*M45

ICD-10 Finland

Iridocyclitis in ankylosing spondylitis

+∞

6.3

NHG82

NOMESCO Finland

Fusion of other tarsal joint

+∞

6.3

NHG76

NOMESCO Finland

Arthroplasty of other tarsometatarsal joint

+∞

6.3

M07.1*L40.5

ICD-10 Finland

Arthritis mutilans

+∞

6.3

7170A

ICD-9 Finland

Internal derangement of knee, Old bucket handle tear of medial meniscus

+∞

6.3

M074K

ICD-10 Finland

+∞

6.3

L04AA11

ATC

[U] etanercept; parenteral

+∞

6.3

7113X

ICD-9 Finland

Arthropathy associated with infections, Postdysenteric arthropathy[ENTEROARTHRITIS, MÄÄRITTELEMÄTÖN]

+∞

6.3

B99

ICD-10 Finland

Other and unspecified infectious diseases

4.8

6.3

A06AC51

ATC

ispaghula, combinations; systemic

2.9

6.3

128

NHK40

NOMESCO Finland

Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone

26.9

6.2

NK4AT

NOMESCO Finland

Puncture of joint with ultrasound guidance not elsewher classified

26.9

6.2

M19.2

ICD-10 Finland

Other secondary arthrosis

26.9

6.2

L40.9

ICD-10 Finland

Psoriasis, unspecified

7.1

6.2

J01MA14

ATC

moxifloxacin; systemic

2.2

6.2

304

M79.7

ICD-10 Finland

Fibromyalgia

4.0

6.2

D07BB04

ATC

hydrocortisone butyrate and antiseptics; topical

1.8

6.2

555

C09CA06

ATC

candesartan; oral

1.7

6.2

139

891

K12.00

ICD-10 Finland

Recurrent oral aphthae

6.3

6.2

ZZH21

NOMESCO Finland

Graft of patients own bone, small pieces

5.8

6.2

T81.0

ICD-10 Finland

Haemorrhage and haematoma complicating a procedure, not elsewhere classified

2.5

6.2

198

K60.2

ICD-10 Finland

Anal fissure, unspecified

4.7

6.1

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

1.9

6.1

517

-1

NOMESCO Finland

1.5

6.1

243

1793

M16.9

ICD-10 Finland

Coxarthrosis, unspecified

4.9

6.1

S91

ICPC

Psoriasis

8.7

6.1

B01AA03

ATC

warfarin; systemic

1.9

6.0

489

5BA08

NOMESCO Finland

10.1

6.0

H05BA01

ATC

calcitonin (salmon synthetic); nasal, parenteral

5.2

6.0

TPH07

NOMESCO Finland

Cathetrisation of artery

2.1

6.0

329

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

2.9

6.0

126

K60.0

ICD-10 Finland

Acute anal fissure

6.1

6.0

D05BB02

ATC

acitretin; oral

4.6

6.0

NAME	M13_ENTEROARTHR
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M07[4-6]
HD_ICD_9	7113
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M07[4-6]
COD_ICD_9	7113
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
M13_ENTEROARTHR	1.395 [1.15, 1.69]	< 0.001
Birth year	0.997 [0.99, 1.01]	0.455

Parameter	HR [95% CI]	p-value
M13_ENTEROARTHR	1.313 [1.08, 1.59]	0.006
Birth year	0.987 [0.98, 1.0]	0.01

N-year risk	Females	Males
1	0.16%	0.23%
5	0.878%	1.55%
10	2.166%	3.741%
15	4.3%	6.91%
20	7.2%	11.991%

Enteropathic arthropathies

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints