Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

C3_AML_MDS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

1316

6. Filter based on genotype QC (FinnGen only)

1316

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1316 507 809
Unadjusted period prevalence (%) 0.29 0.17 0.36
Median age at first event (years) 72.11 69.26 73.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
709
1347
10.24
307.65
7.7
2.1
1.9
1.8
%
2.73
663
1171
456
127
54.41
307.65
4.0
1.3
—
—
—
0
0
328
168
25.67
307.65
1.4
1.2
135.1
19.1
u/l
13.63
291
150
617
984
10.92
307.65
7.4
2.1
68.0
67.6
e9/l
0.05
512
769
447
68
99.03
307.65
1.4
1.1
—
—
—
0
0
411
502
11.45
307.65
2.2
1.6
1.2
1.5
g/l
5.39
349
425
322
239
17.51
307.65
2.5
1.5
—
—
—
0
0
269
67
50.21
307.65
1.8
1.1
—
—
—
0
0
447
684
9.38
299.33
12.7
3.5
1.5
0.7
%
4.65
308
155
215
109
23.38
285.70
10.0
2.9
1.2
1.9
%
0.53
175
76
159
50
36.03
249.86
1.4
1.2
—
—
—
0
0
159
55
32.74
242.56
2.7
2.4
—
—
—
0
0
181
105
19.83
225.32
1.5
1.4
105.3
106.9
u/ml
0.07
49
14
124
21
65.09
224.36
3.8
1.2
—
—
—
0
0
347
548
8.24
221.58
3.3
2.1
10.6
11.0
g/l
0.59
321
497
222
205
12.82
213.19
3.7
2.6
3.5
3.5
g/l
0.12
216
192
361
625
7.58
211.39
12.8
3.5
0.8
0.6
%
1.01
203
114
366
655
7.36
207.46
13.1
3.6
0.2
0.1
%
2.52
277
142
233
246
11.29
204.13
1.7
1.3
—
—
—
0
0
177
123
16.47
200.74
1.4
1.4
—
—
—
0
0
169
115
16.71
193.69
1.3
1.3
276.4
245.3
u/ml
0.43
107
64
413
891
6.30
192.92
2.8
1.6
66.6
66.3
g/l
0.27
389
784
151
84
20.18
191.10
11.5
3.1
—
—
—
0
0
191
169
13.05
187.88
1.3
1.3
—
—
—
0
0
146
79
20.66
187.04
9.7
2.8
47.9
56.0
%
1.66
100
49
336
623
6.90
182.49
13.2
3.7
2.1
0.7
%
0.83
222
121
97
14
74.72
179.66
1.5
1.1
—
—
—
0
0
281
442
7.81
178.00
1.9
1.3
1.4
1.1
g/l
0.84
258
403
97
15
69.73
177.71
1.0
1.0
—
—
—
0
0
88
11
85.66
166.21
4.6
1.0
—
—
—
0
0
251
399
7.54
156.59
1.4
1.3
—
—
—
0
0
726
2987
4.19
144.76
24.0
5.0
—
—
—
0
0
131
96
15.04
143.44
1.2
1.1
—
—
—
0
0
332
761
5.50
141.62
2.5
1.5
—
—
—
0
0
311
681
5.67
139.53
1.5
1.5
—
—
—
0
0
446
1354
4.47
133.93
3.0
2.5
36.5
22.4
%
24.54
380
1136
492
1608
4.29
133.72
2.9
2.4
17.2
12.5
umol/l
18.94
473
1460
132
112
12.99
132.38
1.3
1.0
—
—
—
0
0
436
1323
4.43
130.63
10.2
4.8
1.1
1.0
mmol/l
3.88
413
1196
459
1457
4.30
129.25
2.9
2.4
2.0
2.3
g/l
17.13
443
1339
851
4184
3.93
124.92
25.0
5.5
11.5
8.9
%
17.61
819
3837
833
4046
3.88
124.37
22.0
5.2
0.7
0.6
%
1.46
805
3707
844
4165
3.86
122.31
23.0
5.2
2.2
3.0
%
13.98
813
3800
318
795
4.96
121.14
1.6
1.5
—
—
—
0
0
81
29
29.70
121.10
6.2
1.6
414.8
950.7
e6/l
1.68
40
13
853
4257
3.85
121.08
24.0
5.3
31.0
25.9
%
19.37
822
3891
85
38
23.84
117.28
6.2
3.0
1.0
1.0
e9/l
0.03
43
21
126
121
11.41
116.38
8.3
5.9
11.1
12.5
mg/l
1.80
118
109
428
1421
3.98
111.08
8.7
2.5
0.8
0.8
mmol/l
2.59
402
1290
119
113
11.48
110.66
1.3
1.1
—
—
—
0
0
67
17
41.47
110.46
1.2
1.0
—
—
—
0
0
611
2577
3.56
110.14
7.1
2.5
1104.0
7571.0
umol/l
5.65
572
2142
337
970
4.33
106.15
1.6
1.7
—
—
—
0
0
819
4225
3.48
105.03
21.3
5.2
49.5
58.8
%
49.20
784
3881
622
2721
3.44
104.52
16.1
2.2
—
—
—
0
0
189
340
6.32
103.07
2.4
1.4
47.6
50.0
mg/l
0.16
165
271
186
331
6.38
102.53
2.4
1.4
5.1
1.3
ratio
1.00
13
29
647
2950
3.35
100.65
12.4
4.0
—
—
—
0
0
186
340
6.21
99.69
2.4
1.4
48.8
36.2
mg/l
0.39
161
273
850
4610
3.38
97.78
22.1
5.1
0.1
0.2
e9/l
26.23
772
3970
101
92
11.81
96.37
2.3
1.4
—
—
—
0
0
101
92
11.81
96.37
2.3
1.4
—
—
—
0
0
101
92
11.81
96.37
2.3
1.4
—
—
—
0
0
101
92
11.81
96.37
2.3
1.4
—
—
—
0
0
846
4603
3.35
96.22
20.6
3.7
13.4
12.6
umol/l
0.99
822
4283
883
4963
3.37
94.32
38.5
5.7
3.4
4.5
e9/l
5.46
823
4246
823
4443
3.28
94.10
19.2
4.9
0.7
0.6
e9/l
0.83
753
3761
824
4475
3.25
92.77
19.2
5.0
0.0
0.0
e9/l
2.79
754
3798
429
1612
3.46
89.86
4.1
1.9
29.6
30.1
s
0.93
414
1556
826
4549
3.19
89.64
20.1
5.0
1.6
1.8
e9/l
1.28
769
3919
54
14
40.18
88.32
1.3
1.0
—
—
—
0
0
740
3855
3.10
88.14
5.3
2.8
541.6
139.6
ug/l
17.83
700
3493
598
2767
3.13
87.90
3.1
2.2
3.1
3.0
mg/l
0.58
521
2323
148
254
6.44
84.15
2.6
1.4
—
—
—
0
0
62
29
22.39
83.71
3.0
3.5
15.5
15.2
%
0.02
27
13
757
4078
3.02
83.36
23.6
3.7
—
—
—
0
0
490
2099
3.13
81.20
14.6
2.1
—
—
—
0
0
434
1746
3.22
79.95
17.7
4.0
—
—
—
0
0
57
27
22.02
76.49
44.8
27.4
146.7
145.8
ug/l
0.02
57
22
287
917
3.72
75.98
11.7
2.6
8.6
9.2
umol/l
0.21
274
771
281
906
3.67
73.19
8.7
5.7
9.9
11.5
mmol/l
2.31
268
839
59
35
17.60
71.56
2.6
1.9
40.2
44.6
%
0.34
20
17
821
4949
2.75
67.66
14.9
5.4
1.2
1.2
mmol/l
5.21
708
4127
508
2426
2.78
66.45
2.2
1.8
1327.1
1165.6
nmol/l
2.78
414
1814
368
1488
3.04
65.49
1.7
1.3
2.6
2.7
g/l
0.26
286
843
168
408
4.57
64.31
2.1
1.4
11.8
10.5
g/l
1.90
144
339
176
449
4.37
63.21
2.6
1.7
6.6
1.9
ug/l
0.91
154
387
751
4481
2.57
60.73
12.6
5.1
1.2
1.2
mmol/l
4.86
708
3932
114
209
5.88
60.21
1.5
1.2
—
—
—
0
0
706
4168
2.50
57.27
12.4
3.7
33.3
34.9
g/l
7.92
670
3788
107
204
5.62
54.13
1.3
2.1
24.1
11.8
mg/l
1.41
89
187
37
14
27.16
53.78
3.2
5.1
—
—
—
0
0
534
2851
2.47
52.93
10.7
3.1
7.4
7.4
ph
1.14
101
498
319
1358
2.78
50.13
2.3
2.0
—
—
—
0
0
53
5
110.38
49.15
1.4
1.0
—
—
—
0
0
396
1898
2.55
48.84
2.6
1.7
2.7
1.3
mg/l
3.49
345
1472
132
341
4.19
46.24
2.1
1.4
37.1
37.0
g/l
0.07
116
282
55
61
9.37
45.37
1.2
1.1
—
—
—
0
0
496
2712
2.33
44.98
2.1
1.6
20.3
19.9
nmol/l
0.26
463
2261
34
20
17.42
41.16
1.1
1.0
—
—
—
0
0
51
59
8.95
40.71
2.5
1.6
—
—
—
0
0
41
35
12.06
40.44
1.2
1.1
—
—
—
0
0
397
2086
2.29
38.47
28.2
4.4
—
—
—
0
0
694
4591
2.08
36.75
2.9
2.1
89.5
92.4
pmol/l
0.88
484
2363
401
2161
2.23
36.20
10.2
3.6
78.5
81.8
%
1.91
392
2097
153
532
3.12
33.97
2.8
1.4
11.6
4.0
ug/l
0.47
119
403
30
21
14.60
33.15
2.0
1.1
—
—
—
0
0
395
2180
2.16
33.12
2.1
1.3
—
—
—
0
0
243
1102
2.48
32.31
1.8
1.8
—
—
—
0
0
182
742
2.69
30.04
2.2
2.0
0.2
0.2
g/l
0.02
158
661
230
1062
2.41
29.19
1.5
1.3
604.8
530.6
titre
0.22
67
241
795
5848
1.91
27.70
10.4
4.4
6.9
6.9
mmol/l
0.07
773
5468
217
998
2.41
27.69
2.9
1.4
—
—
—
0
0
29
28
10.57
26.30
1.1
1.1
—
—
—
0
0
915
7125
1.93
25.91
25.6
5.2
82.7
78.1
u/l
1.75
888
6522
24
0
+∞
25.08
1.8
0.0
19.5
—
%
—
24
0
62
144
4.47
24.79
8.9
3.0
51.0
59.3
%
2.91
62
144
464
2956
1.88
24.54
3.2
2.3
52.5
57.7
u/l
2.28
428
2700
142
570
2.67
23.99
4.4
3.1
3.4
4.2
e9/l
1.45
98
392
617
4318
1.81
23.87
9.8
11.8
1.3
1.4
inr
2.69
164
1181
30
35
8.75
23.71
1.7
1.2
57.2
66.7
mg/l
0.31
24
23
25
23
11.06
23.38
1.2
1.1
—
—
—
0
0
417
2641
1.85
21.99
2.5
1.7
—
—
—
0
0
563
3922
1.76
21.42
34.8
8.7
0.1
0.0
e9/l
0.68
488
3154
20
15
13.52
21.12
1.3
1.3
—
—
—
0
0
26
31
8.54
20.18
1.2
1.1
—
—
—
0
0
414
2702
1.78
19.29
4.6
3.1
0.6
0.5
e6/l
0.42
327
2086
18
0
+∞
18.79
1.1
0.0
—
—
—
0
0
446
3010
1.73
18.28
4.7
3.2
151.1
92.8
e6/l
0.34
361
2359
50
125
4.12
18.20
1.1
1.1
—
—
—
0
0
462
3160
1.71
17.97
4.3
2.1
2.3
2.3
mmol/l
5.71
398
2575
22
6
37.25
17.64
1.2
1.0
—
—
—
0
0
262
1528
1.89
17.38
4.2
3.0
2.0
2.2
e6/l
0.17
145
864
196
1036
2.05
17.29
9.2
3.7
—
—
—
0
0
159
785
2.17
16.76
2.0
1.7
360.4
371.6
nmol/l
0.28
154
705
391
2602
1.72
16.55
4.6
3.1
—
—
—
0
0
201
1098
1.98
16.12
6.8
6.1
94.3
94.8
%
0.42
193
1049
40
93
4.40
16.00
1.9
1.2
—
—
—
0
0
459
3213
1.66
15.93
4.3
3.3
—
—
—
0
0
49
134
3.76
15.78
1.1
1.3
161.9
263.0
miu/ml
—
6
47
486
3458
1.64
15.78
5.4
3.6
59.3
128.9
e6/l
2.49
379
2517
270
1635
1.82
15.75
4.0
2.8
1.8
1.2
e6/l
0.65
157
966
504
3631
1.63
15.50
3.6
3.2
2040.9
1909.3
ng/l
0.28
464
3136
799
6442
1.61
15.29
6.7
4.7
156.3
3047.9
e6/l
2.02
15
129
181
980
1.98
14.83
7.2
6.2
102.9
121.0
g/l
21.51
176
942
213
1219
1.89
14.80
6.3
5.9
11.1
11.3
kpa
0.27
206
1153
213
1219
1.89
14.80
6.3
6.0
4.9
5.1
kpa
1.48
206
1155
102
440
2.43
14.74
7.1
4.2
24.9
24.7
mmol/l
0.18
95
396
143
713
2.13
14.65
6.1
3.8
7.4
7.4
ph
0.89
18
85
144
726
2.10
14.33
6.1
3.8
5.1
5.2
kpa
0.18
131
664
31
64
4.94
14.31
1.2
1.3
—
—
—
0
0
361
2433
1.67
14.21
1.7
1.8
42907071.5
10534772.1
pmol/l
0.34
289
1965
210
1217
1.86
13.99
6.7
5.9
1.1
1.3
mmol/l
0.20
163
918
128
625
2.16
13.82
1.7
1.1
—
—
—
0
0
191
1078
1.90
13.80
4.7
3.4
1.5
2.0
mmol/l
0.81
151
839
167
901
1.98
13.79
6.0
5.6
1.6
1.5
mmol/l
0.36
160
853
191
1085
1.89
13.52
4.8
3.4
5.7
5.8
kpa
1.03
186
1036
22
35
6.38
13.31
1.4
1.1
—
—
—
0
0
64
232
2.85
13.11
4.5
4.2
1.4
1.6
mg/l
1.15
58
202
30
65
4.70
13.10
1.2
1.1
—
—
—
0
0
43
123
3.58
13.01
2.4
2.9
—
—
—
0
0
40
113
3.62
12.33
1.5
1.6
230222.3
79991.2
e6/l
0.38
26
69
108
517
2.19
12.25
6.5
4.0
—
—
—
0
0
42
124
3.47
12.13
1.5
1.5
1254.4
1529.6
e6/l
0.29
35
88
163
911
1.90
12.08
4.4
3.4
—
—
—
0
0
16
6
26.96
12.06
1.3
1.0
—
—
—
0
0
94
428
2.29
12.03
1.3
1.5
—
—
—
0
0
836
7001
1.53
12.03
6.3
4.1
24.5
13.5
mm/h
30.69
780
6367
318
2154
1.63
11.99
4.7
4.3
198.0
443.2
ng/l
2.19
275
1855
18
26
7.01
11.87
7.8
1.4
—
—
—
0
0
12
10
12.10
11.75
1.0
1.0
—
—
—
0
0
139
743
1.97
11.74
2.4
2.1
43.6
32.0
u/l
0.49
119
604
106
514
2.16
11.64
8.5
8.6
—
—
—
0
0
95
445
2.22
11.37
1.4
1.3
—
—
—
0
0
201
1230
1.75
11.04
1.3
1.2
—
—
—
0
0
311
2133
1.60
11.03
3.6
2.5
5.4
5.2
e6/l
0.08
284
1868
135
731
1.94
10.98
6.7
6.2
24.4
24.4
mmol/l
0.06
128
680
37
110
3.43
10.60
1.5
1.6
—
—
—
0
0
135
741
1.92
10.54
4.7
4.3
—
—
—
0
0
150
857
1.85
10.35
8.3
6.8
—
—
—
0
0
28
70
4.07
10.25
1.3
1.4
—
—
—
0
0
290
1989
1.59
10.20
3.9
2.7
532.2
552.0
mosm/kgh2o
0.99
261
1677
26
63
4.19
9.92
1.2
1.2
—
—
—
0
0
101
515
2.04
9.73
4.6
3.8
24.3
24.2
mmol/l
0.04
90
446
52
199
2.68
9.67
2.9
2.6
33.5
35.1
umol/l
0.18
38
174
35
108
3.30
9.48
1.5
1.7
0.9
1.0
g/l
0.09
27
84
30
85
3.59
9.26
1.2
1.1
—
—
—
0
0
22
50
4.46
9.10
1.5
1.3
—
—
—
0
0
104
554
1.95
8.87
3.0
2.4
—
—
—
0
0
20
43
4.71
8.84
7.6
3.1
—
—
—
0
0
26
71
3.72
8.47
1.3
1.4
0.6
0.4
g/l
0.91
17
53
26
71
3.72
8.47
1.3
1.4
2.9
2.9
g/l
0.01
19
53
26
71
3.72
8.47
1.3
1.4
6.4
7.4
g/l
0.57
19
53
32
102
3.19
8.26
1.7
1.5
—
—
—
0
0
64
293
2.24
8.15
1.4
1.2
3.0
0.2
u/ml
—
9
26
131
774
1.77
8.07
5.3
2.9
1.2
1.2
mmol/l
2.26
125
644
50
207
2.47
7.98
1.2
1.2
92.9
88.0
titre
—
7
15
776
6672
1.40
7.90
6.5
4.4
—
—
—
0
0
61
279
2.24
7.79
5.3
3.5
—
—
—
0
0
528
4265
1.40
7.76
5.1
4.3
69.0
71.8
ng/l
0.04
425
3240
31
102
3.09
7.61
1.5
1.6
—
—
—
0
0
26
78
3.38
7.40
1.2
1.2
3.4
6.7
u/ml
0.59
14
35
13
22
5.96
7.38
1.2
1.1
1.6
1.2
ug/l
—
7
11
7
0
+∞
7.30
1.4
0.0
—
—
—
0
0
108
622
1.80
7.26
8.4
7.4
1.7
1.3
%
2.35
108
617
85
461
1.90
6.91
6.0
4.2
0.9
0.9
%
0.01
79
435
50
223
2.29
6.81
1.3
1.2
1.7
3.0
u/ml
—
7
20
30
104
2.93
6.77
2.9
2.1
2.5
3701.8
u/l
—
7
37
172
1144
1.58
6.74
3.5
3.2
281.4
275.3
ng/l
0.07
153
1063
31
110
2.86
6.71
2.4
1.3
21.4
23.9
iu/l
0.18
22
94
51
231
2.26
6.70
7.0
6.0
11.1
11.2
mmol/l
0.06
46
208
51
231
2.26
6.70
7.0
6.0
104.8
105.6
mmol/l
0.43
46
208
67
339
2.03
6.66
6.2
5.3
1.3
1.4
mmol/l
0.28
62
301
21
60
3.54
6.45
1.2
1.7
13.6
14.4
umol/l
0.17
21
52
49
223
2.24
6.38
1.2
1.2
—
602.0
—
0
5
9
5
18.11
6.27
2.6
1.0
—
—
—
0
0
9
5
18.11
6.27
2.6
1.0
—
—
—
0
0
9
5
18.11
6.27
2.6
1.0
—
—
—
0
0
6
0
+∞
6.25
1.0
0.0
—
—
—
0
0
559
4675
1.34
6.19
4.7
3.8
0.0
0.0
estimate
0.00
107
811
41
175
2.39
6.19
2.2
1.2
—
—
—
0
0
129
823
1.63
6.00
3.4
3.8
81.8
93.4
ng/l
0.99
111
695
48
224
2.19
5.91
4.6
3.7
—
—
—
0
0
83
472
1.81
5.85
5.4
4.1
1.8
1.7
%
0.42
78
447
170
2406
0.66
5.83
2.2
1.6
1.5
1.3
mmol/l
2.39
154
1984
34
137
2.52
5.81
2.2
2.5
—
—
—
0
0
842
9260
0.75
5.75
4.8
5.4
2.3
2.5
mmol/l
16.13
757
8347
48
228
2.15
5.66
6.4
4.5
2.5
2.8
mmol/l
0.29
34
150
54
272
2.03
5.48
6.2
4.2
7.4
7.4
ph
0.77
46
222
192
2613
0.69
5.32
3.2
3.3
—
—
—
0
0
43
201
2.18
5.30
2.2
1.3
661.2
768.0
e6/l
0.06
38
176
557
4739
1.30
5.18
4.8
3.9
0.0
0.0
estimate
0.50
101
789
18
55
3.30
5.03
1.3
1.5
14.6
16.1
ug/l
0.33
18
55
801
8811
0.77
5.02
6.2
6.6
39.9
41.2
mmol/mol
3.20
728
8020
22
77
2.89
4.94
2.2
1.1
—
—
—
0
0
42
201
2.13
4.90
2.2
1.2
11.8
45.4
e6/l
0.63
36
172
52
271
1.96
4.83
1.3
1.1
—
—
—
0
0
405
3325
1.31
4.81
2.6
2.2
309.7
273.0
u/l
0.07
378
3104
11
24
4.61
4.78
2.5
2.0
—
—
—
0
0
10
20
5.03
4.78
1.6
1.1
—
—
—
0
0
546
4671
1.29
4.75
6.4
5.2
0.0
0.0
estimate
0.00
104
803
134
914
1.52
4.70
4.2
3.0
4.5
4.4
kpa
0.10
129
867
31
134
2.35
4.62
2.5
1.5
17.3
7.8
u/l
1.21
25
114
70
409
1.75
4.56
2.3
2.1
657.0
511.5
ug/l
0.20
62
379
40
194
2.10
4.53
1.4
1.5
—
—
—
0
0
49
257
1.94
4.49
1.7
1.6
21416.8
17791.6
e6/l
0.26
38
184
23
88
2.64
4.41
7.1
3.2
—
—
—
0
0
20
71
2.84
4.40
1.6
1.7
—
1.3
—
0
5
16
50
3.23
4.34
1.4
1.1
—
—
—
0
0
14
40
3.53
4.34
1.5
1.1
—
—
—
0
0
818
8903
0.79
4.23
4.4
4.7
1.3
1.4
mmol/l
15.05
730
7998
15
46
3.29
4.19
1.1
1.1
—
—
—
0
0
12
32
3.78
4.09
1.2
1.4
—
—
—
0
0
82
519
1.62
4.01
9.0
7.6
23.7
24.4
mmol/l
0.76
77
464
89
575
1.59
4.00
2.8
2.6
0.6
0.3
e6/l
0.44
89
558
14
43
3.28
3.91
1.2
1.0
—
—
—
0
0
9
15
6.03
3.82
1.7
1.5
—
—
—
0
0
17
60
2.86
3.80
2.3
2.0
—
—
—
0
0
289
2332
1.31
3.79
4.9
3.8
—
—
—
0
0
6
5
12.05
3.76
1.0
3.2
—
—
—
0
0
24
102
2.38
3.75
1.2
1.2
—
—
—
0
0
49
274
1.82
3.75
3.7
3.5
7.5
7.9
kpa
0.94
43
255
73
458
1.63
3.71
5.6
4.5
—
—
—
0
0
127
902
1.45
3.68
1.9
2.0
185.0
161.6
ug/g
0.20
101
693
72
452
1.63
3.66
1.6
1.2
317.1
279.3
u/ml
0.10
67
412
104
713
1.50
3.60
4.3
2.9
103.5
128.8
g/l
20.24
99
696
835
9002
0.80
3.57
4.6
4.7
4.0
4.4
mmol/l
24.97
754
8143
42
228
1.87
3.54
3.3
2.5
13.5
16.1
%
3.13
23
115
43
237
1.84
3.46
1.6
1.2
—
—
—
0
0
315
2600
1.28
3.45
5.0
4.1
0.0
0.0
estimate
0.00
98
763
43
238
1.83
3.42
1.3
1.4
247.6
308.4
ug/g
1.02
24
144
32
161
2.01
3.36
1.5
1.3
—
—
—
0
0
11
32
3.46
3.33
1.1
1.1
1474.3
1719.0
miu/ml
0.32
11
32
11
33
3.35
3.19
1.3
1.3
—
0.1
—
0
5
7
11
6.39
3.18
1.1
1.0
—
—
—
0
0
116
835
1.43
3.15
1.4
1.3
—
—
—
0
0
215
1707
1.31
3.15
22.2
30.6
1.3
1.5
inr
0.79
32
237
29
145
2.02
3.12
1.4
1.1
—
—
—
0
0
8
228
0.35
3.07
1.1
1.1
—
—
—
0
0
6
8
7.53
3.05
1.0
1.0
—
—
—
0
0
6
8
7.53
3.05
1.0
1.0
—
—
—
0
0
39
218
1.81
3.04
3.1
2.9
—
—
—
0
0
58
363
1.63
3.03
3.3
2.8
0.3
0.3
g/l
0.44
32
124
7
12
5.86
3.02
1.1
1.2
—
—
—
0
0
9
21
4.31
2.99
3.2
2.5
—
—
—
0
0
5
5
10.03
2.98
1.8
1.0
—
—
—
0
0
5
5
10.03
2.98
1.4
1.2
265.0
242.8
nmol/l
—
5
5
11
35
3.16
2.93
1.9
1.3
64.0
60.1
%
0.13
11
28
35
192
1.85
2.90
1.3
1.5
59.7
63.7
mmol/l
0.19
27
157
15
58
2.60
2.88
1.1
1.1
—
—
—
0
0
55
345
1.62
2.86
2.3
1.8
—
—
—
0
0
185
2314
0.77
2.84
3.2
2.7
0.8
0.8
ug/l
0.07
117
1651
32
173
1.87
2.78
1.3
1.4
—
—
—
0
0
9
23
3.93
2.77
1.2
1.4
—
—
—
0
0
176
1384
1.31
2.77
1.3
1.3
28.7
39.5
iu/ml
0.54
53
436
5
6
8.36
2.75
1.0
1.0
—
—
—
0
0
16
66
2.44
2.71
4.1
2.8
—
—
—
0
0
18
375
0.47
2.66
1.4
1.4
—
—
—
0
0
22
106
2.09
2.63
1.0
1.3
410.0
329.1
nmol/l
0.80
16
88
147
1137
1.33
2.61
2.9
2.5
4.8
6.9
ug/l
1.74
119
978
42
253
1.68
2.57
2.5
2.2
105.1
130.8
g/l
7.18
33
191
10
33
3.05
2.53
1.1
1.2
100.8
136.2
iu/ml
—
10
33
49
309
1.61
2.53
2.4
3.4
0.8
0.8
nmol/l
0.10
29
239
169
1340
1.30
2.52
1.3
1.3
19.1
14.2
u/ml
0.24
55
489
863
9153
0.83
2.49
5.7
5.0
6.1
6.1
mmol/l
0.41
767
8134
806
8598
0.84
2.47
4.8
4.2
1.3
1.3
mmol/l
0.82
725
7650
18
83
2.18
2.41
2.6
1.1
—
—
—
0
0
8
22
3.65
2.36
4.0
1.9
—
—
—
0
0
13
290
0.44
2.34
1.8
1.5
—
—
—
0
0
15
65
2.32
2.32
1.9
1.7
—
—
—
0
0
9
28
3.23
2.31
1.1
1.6
—
—
—
0
0
61
418
1.48
2.21
2.9
2.9
4.3
4.4
pmol/l
0.69
54
358
52
346
1.52
2.17
1.5
1.2
—
—
—
0
0
61
868
0.69
2.17
1.6
1.6
—
—
—
0
0
9
30
3.01
2.15
2.1
1.4
1.6
2.0
%
—
9
25
350
3070
1.19
2.06
5.4
4.4
—
—
—
0
0
11
44
2.51
2.01
1.3
1.1
—
—
—
0
0
7
21
3.35
1.96
3.0
1.9
—
—
—
0
0
226
1917
1.22
1.90
3.1
2.3
2.4
2.4
mmol/l
1.74
204
1623
23
128
1.81
1.90
1.5
1.4
54.0
68.8
%
0.83
16
87
97
744
1.33
1.88
4.8
4.0
—
—
—
0
0
972
9290
1.18
1.85
53.1
14.9
30.2
26.0
mg/l
3.20
917
7393
12
53
2.28
1.81
1.5
1.8
2.0
6.0
u/field
—
5
41
18
94
1.93
1.80
1.6
1.3
24363.6
274374.2
e6/l
1.23
13
61
21
116
1.82
1.79
1.5
1.3
—
—
—
0
0
8
30
2.68
1.72
1.8
2.6
23.4
27.7
umol/l
—
8
30
16
82
1.96
1.70
1.0
1.2
—
—
—
0
0
6
20
3.01
1.58
1.0
1.1
—
—
—
0
0
6
20
3.01
1.58
1.5
1.4
—
—
—
0
0
984
10199
0.86
1.57
77.6
21.5
7.9
6.9
e9/l
0.69
954
9778
984
10199
0.86
1.57
78.2
21.6
108.7
134.1
g/l
211.34
961
9944
984
10197
0.86
1.56
77.6
21.5
3.6
4.4
e12/l
173.71
950
9775
984
10197
0.86
1.56
77.2
21.4
31.3
30.4
pg
19.02
965
9941
984
10196
0.86
1.55
77.8
21.4
185.6
239.7
e9/l
34.37
952
9819
984
10194
0.86
1.54
77.4
21.4
95.1
91.6
fl
40.15
964
9937
10
206
0.48
1.53
1.6
1.7
—
—
—
0
0
12
231
0.52
1.51
1.0
1.1
—
—
—
0
0
25
156
1.61
1.44
3.1
2.2
4.0
4.1
mmol/l
0.41
25
156
25
156
1.61
1.44
3.1
2.2
106.1
105.1
mmol/l
0.69
25
156
5
16
3.13
1.44
1.4
1.2
—
—
—
0
0
5
16
3.13
1.44
3.6
3.9
—
—
—
0
0
14
74
1.90
1.39
1.2
1.5
—
—
—
0
0
24
152
1.59
1.32
3.2
2.2
—
—
—
0
0
15
83
1.82
1.31
1.9
2.4
8.5
7.1
mmol/l
—
9
53
10
48
2.09
1.28
5.4
2.9
21.9
19.4
nmol/l
—
10
39
10
48
2.09
1.28
1.3
1.4
—
1837.4
—
0
17
9
44
2.05
1.27
1.1
1.7
—
—
—
0
0
5
19
2.64
1.21
1.0
1.1
—
—
—
0
0
256
2286
1.15
1.20
5.1
4.2
1.0
1.0
kg/l
0.04
43
365
269
2411
1.15
1.19
4.2
3.5
—
—
—
0
0
13
72
1.81
1.15
2.1
1.1
—
—
—
0
0
198
1744
1.16
1.12
1.3
1.2
2.7
1.5
u/ml
0.47
48
453
11
58
1.90
1.12
1.2
1.6
—
—
—
0
0
8
40
2.01
1.12
1.3
2.9
—
—
—
0
0
13
73
1.79
1.11
2.1
1.1
—
—
—
0
0
7
32
2.19
1.08
3.6
2.5
—
—
—
0
0
726
7587
0.90
1.06
70.2
19.6
328.8
331.9
g/l
11.86
717
7493
18
114
1.59
1.03
1.4
1.4
—
—
—
0
0
16
100
1.61
0.97
1.3
1.3
—
—
—
0
0
83
691
1.21
0.93
1.6
1.5
—
—
—
0
0
10
55
1.82
0.92
1.9
1.3
—
—
—
0
0
68
555
1.24
0.91
1.2
1.2
—
—
—
0
0
56
447
1.26
0.91
1.1
1.2
53.8
121.4
iu/ml
1.61
17
172
41
315
1.31
0.89
5.0
4.4
—
—
—
0
0
8
42
1.91
0.88
1.0
1.2
110.3
138.4
nmol/l
—
8
42
12
73
1.65
0.81
1.2
1.7
—
—
—
0
0
6
34
1.77
0.76
1.7
1.6
—
—
—
0
0
49
396
1.25
0.75
2.3
2.1
—
—
—
0
0
34
263
1.30
0.73
6.2
2.9
8.0
7.7
mmol/l
0.20
34
257
51
416
1.24
0.73
1.3
1.3
—
—
—
0
0
75
639
1.18
0.70
1.1
1.1
—
—
—
0
0
5
27
1.85
0.68
1.0
1.0
—
—
—
0
0
5
27
1.85
0.68
1.6
1.3
78.8
155.3
nmol/l
—
5
21
643
6670
0.93
0.66
5.7
4.3
—
—
—
0
0
718
6941
1.08
0.66
4.2
3.7
15.0
15.1
pmol/l
0.42
647
6138
957
9777
0.92
0.65
31.6
9.2
27.5
24.5
u/l
0.65
927
9263
930
9506
0.93
0.62
42.1
14.7
—
—
—
0
0
327
3470
0.92
0.61
4.1
4.0
12.5
8.7
mg/mmol
0.46
218
2225
0
22
0.00
0.59
0.0
8.0
—
—
—
0
0
757
7360
1.07
0.55
67.2
17.5
16.4
13.8
%
84.90
751
7133
10
65
1.54
0.55
2.5
2.4
—
—
—
0
0
9
61
1.48
0.53
1.1
1.3
—
—
—
0
0
320
3375
0.93
0.51
3.4
3.2
6.9
7.3
mmol/l
0.93
271
2795
6
41
1.47
0.50
2.3
1.2
—
—
—
0
0
7
46
1.52
0.48
1.9
1.3
—
—
—
0
0
39
332
1.18
0.42
1.2
1.1
—
169.0
titre
—
0
9
16
206
0.77
0.41
2.4
1.3
0.8
0.8
nmol/l
0.13
11
168
313
3276
0.94
0.41
3.5
3.2
1797.4
194.1
mg/l
2.28
229
2104
820
8036
1.05
0.41
52.6
16.2
32.4
38.8
%
44.82
475
4972
21
168
1.25
0.40
1.6
1.9
1.7
4.7
iu/l
—
6
62
19
150
1.27
0.40
2.4
3.0
—
—
—
0
0
21
170
1.24
0.37
2.0
2.2
58.9
62.0
%
0.25
21
170
65
589
1.11
0.32
4.7
3.7
—
—
—
0
0
11
84
1.31
0.30
1.4
1.6
—
—
—
0
0
12
94
1.28
0.28
5.0
3.3
19.1
37.8
mg/l
—
7
78
10
128
0.78
0.27
1.8
2.7
—
—
—
0
0
843
8544
0.96
0.26
5.0
4.5
2.1
2.1
mu/l
0.00
772
7599
14
114
1.23
0.25
1.3
1.2
0.6
0.7
nmol/l
0.09
14
107
12
148
0.81
0.24
1.7
1.4
—
—
—
0
0
10
78
1.28
0.24
1.5
2.1
8.0
10.5
%
—
10
78
974
9834
0.96
0.23
52.2
18.4
4.0
4.0
mmol/l
1.57
954
9499
5
40
1.25
0.22
4.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
1.8
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
206.4
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
17
147
1.16
0.18
1.2
1.3
—
—
—
0
0
28
252
1.11
0.18
4.4
3.6
45.2
29.0
mg/l
1.37
21
170
27
243
1.11
0.17
2.9
2.4
—
—
—
0
0
8
69
1.16
0.16
1.6
1.1
—
—
—
0
0
8
72
1.11
0.16
1.3
1.3
—
—
—
0
0
6
80
0.75
0.15
1.3
1.6
—
—
—
0
0
975
9816
0.97
0.15
48.3
18.2
138.9
139.7
mmol/l
17.86
952
9497
65
686
0.94
0.14
1.4
1.4
—
—
—
0
0
13
112
1.16
0.14
2.3
1.9
—
—
—
0
0
25
229
1.09
0.12
1.7
2.7
—
—
—
0
0
12
104
1.16
0.12
1.3
1.2
—
—
—
0
0
11
125
0.88
0.10
1.6
1.5
—
—
—
0
0
14
155
0.90
0.09
1.8
1.4
—
—
—
0
0
14
155
0.90
0.09
1.8
1.4
—
—
—
0
0
11
124
0.89
0.09
1.4
1.7
—
—
—
0
0
11
97
1.14
0.09
2.4
2.4
965.0
630.7
ml
—
6
63
5
62
0.81
0.08
1.2
1.5
—
—
—
0
0
20
215
0.93
0.07
1.1
1.1
—
—
—
0
0
36
343
1.05
0.07
22.1
11.4
—
—
—
0
0
74
721
1.03
0.06
2.9
3.1
—
—
—
0
0
30
287
1.05
0.05
1.7
1.6
—
—
—
0
0
418
4206
0.99
0.04
4.8
4.0
2.1
2.2
ug/l
0.36
358
3718
29
297
0.98
0.01
2.4
2.3
193.0
122.5
ug/min
0.31
14
176
15
154
0.97
0.00
1.7
1.4
—
—
—
0
0
10
98
1.02
0.00
1.7
1.6
—
—
—
0
0
15
152
0.99
0.00
1.8
1.5
—
—
—
0
0
11
105
1.05
0.00
2.1
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
21.3
—
0
5
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
10
100
1.00
0.00
1.2
1.2
—
—
nmol/l
—
0
0
5
59
0.85
0.00
1.2
1.4
—
—
—
0
0
14
140
1.00
0.00
1.6
1.9
171.4
225.7
pmol/l
2.14
14
130
8
81
0.99
0.00
20.0
13.8
—
—
—
0
0
5
59
0.85
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
311.3
—
0
8

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_AML_MDS_EXALLC – Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).