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Lymphoid leukaemia

CD2_LYMPHOID_LEUKAEMIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C91
  • Hospital discharge: ICD-9 204
  • Hospital discharge: ICD-8 204
  • Cause of death: ICD-10 C91
  • Cause of death: ICD-9 204
  • Cause of death: ICD-8 204

2 out of 7 registries used, show all original rules.

2041

4. Check minimum number of events

None

2041

5. Include endpoints

None

2041

6. Filter based on genotype QC (FinnGen only)

2041

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
C81-C96
Name in latin
Leuc(h)aemia lymphatica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2041 789 1252
Unadjusted period prevalence (%) 0.44 0.27 0.55
Median age at first event (years) 65.11 62.88 66.51

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1871
Matched controls
18711
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
323.0
402
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
13147.4
323.0
1364
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
3338.4
323.0
698
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
64.4
323.0
1036
354
XW000
NOMESCO Finland
Bone marrow biopsy
30.2
323.0
662
333
L03AA02
ATC
filgrastim; parenteral
23.8
245.6
360
185
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
66.0
218.2
252
44
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
213.7
201
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.9
211.7
436
505
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
+∞
194.2
183
*
M04AA01
ATC
allopurinol; systemic
5.4
181.7
661
1718
A04AA01
ATC
ondansetron; systemic, rectal
9.1
178.1
407
555
L01BB05
ATC
fludarabine; systemic
1664.5
156.5
150
*
L01BB02
ATC
mercaptopurine; oral
50.0
146.0
177
39
L01AA02
ATC
chlorambucil; oral
104.8
141.5
154
16
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.8
135.9
539
1466
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
29.5
124.7
170
63
WW500
NOMESCO Finland
Blood transfusion
9.4
124.4
273
335
R50.9
ICD-10 Finland
Fever, unspecified
4.2
115.0
516
1549
B73
ICPC
Leukaemia
382.2
109.5
109
*
C91.7
ICD-10 Finland
Other lymphoid leukaemia
+∞
109.4
104
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
18.4
109.4
173
103
J05AB11
ATC
valaciclovir; oral
4.4
103.0
433
1207
TAB00
NOMESCO Finland
Lumbar puncture
8.4
98.1
229
307
390
Kela drug reimbursment
Ibrutinib
340.4
95.9
96
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
+∞
95.6
91
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
16.8
94.9
155
100
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
91.4
87
*
H02AB09
ATC
hydrocortisone; systemic
11.9
90.4
172
158
1512
Kela drug reimbursment
Ibrutinib
464.2
90.0
89
*
ZX120
NOMESCO Finland
Intravenous
4.4
86.9
353
937
C83.00
ICD-10 Finland
Lymphocytic lymphoma
75.0
82.1
93
13
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
+∞
79.7
76
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
54.3
78.1
93
18
L03AA13
ATC
pegfilgrastim; parenteral
8.0
77.0
184
253
399
Kela drug reimbursment
Venetoclax
+∞
75.5
72
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.6
73.9
389
1283
L01XE27
ATC
[U] ibrutinib; oral
746.6
73.7
72
*
ZX108
NOMESCO Finland
Inhalation
28.0
73.4
101
38
L01AA01
ATC
cyclophosphamide; systemic
40.2
73.0
92
24
JN4BD
NOMESCO Finland
Extensive body CT
3.6
71.8
377
1238
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
10.2
71.3
146
154
D70.89
ICD-10 Finland
Neutropenic splenomegaly
16.9
67.4
109
68
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
35.0
67.0
87
26
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
66.2
996
6133
2040A
ICD-9 Finland
Lymphoid leukaemia, Acute
+∞
66.0
63
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
36.1
64.4
83
24
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.8
64.3
155
215
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
16.9
60.7
98
61
J05AB01
ATC
aciclovir; systemic
2.8
60.4
477
2053
1XC02
NOMESCO Finland
NA
24.7
59.8
85
36
L01XX52
ATC
venetoclax; oral
+∞
59.7
57
*
H02AB02
ATC
dexamethasone; systemic
3.6
58.0
291
909
L01EL01
ATC
ibrutinib; oral
564.2
55.9
55
*
J01MA12
ATC
levofloxacin; systemic
2.5
52.4
491
2304
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.5
52.0
141
231
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
6.9
51.5
134
207
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
51.5
637
3444
ZX131
NOMESCO Finland
Intrathecal
511.2
50.7
50
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
5.3
50.3
163
333
1518
Kela drug reimbursment
NA
+∞
50.2
48
*
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
42.6
50.0
62
15
9823/3-C77.9
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of lymph node, NOS
256.7
49.3
50
*
A41.9
ICD-10 Finland
Sepsis, unspecified
5.0
49.3
168
363
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4.9
48.1
166
363
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
+∞
48.1
46
*
C90.0
ICD-10 Finland
Multiple myeloma
11.8
47.9
90
80
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
48.0
46.3
56
12
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
11.1
46.0
89
84
127
Kela drug reimbursment
Transplant complication
9.9
45.9
94
99
212
Kela drug reimbursment
Gout
6.6
45.4
122
197
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
10.9
43.2
84
80
H02AB06
ATC
prednisolone; systemic
2.0
42.2
930
6260
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
115.2
41.9
45
*
WW200
NOMESCO Finland
Immunization
6.1
41.4
117
202
A05AA02
ATC
ursodeoxycholic acid; oral
10.4
39.7
79
79
C91
ICD-10 Finland
Lymphoid leukaemia
+∞
38.7
37
*
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
43.7
38.2
47
11
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
85.9
37.9
42
5
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
37.8
268
1048
2041A
ICD-9 Finland
Lymphoid leukaemia, Chronic
+∞
37.6
36
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
11.7
37.4
70
62
JN6AD
NOMESCO Finland
CT of torso and neck
12.9
36.4
65
52
J01MA14
ATC
moxifloxacin; systemic
2.9
36.2
238
887
ZX112
NOMESCO Finland
Subcutaneous
6.5
35.9
96
154
372
Kela drug reimbursment
Idelalisib
+∞
35.5
34
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
35.1
184
585
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
11.8
34.9
65
57
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.2
34.8
111
222
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
7.1
34.7
87
128
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.2
34.5
138
349
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.5
33.9
82
114
J02AC03
ATC
voriconazole; systemic
46.5
33.8
41
9
20400
ICD-8 Finland
Lymphatic leukaemia, Acute
+∞
33.4
32
*
L01XX47
ATC
[U] idelalisib; oral
+∞
32.4
31
*
C90.1
ICD-10 Finland
Plasma cell leukaemia
+∞
31.3
30
*
1CX01
NOMESCO Finland
NA
71.1
30.9
35
5
B02.9
ICD-10 Finland
Zoster without complication
3.3
30.1
161
519
1XX02
NOMESCO Finland
NA
307.1
29.9
30
*
9101
FHL
Bone biopsy
108.5
29.7
32
*
6BA02
NOMESCO Finland
NA
24.6
29.2
41
17
189
Kela drug reimbursment
Imatinib
28.4
28.9
39
14
1AA09
NOMESCO Finland
NA
49.4
28.4
34
7
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
13.6
28.3
49
37
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.7
27.6
203
805
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.3
26.7
140
444
WW409
NOMESCO Finland
Other aferesis
46.4
26.5
32
7
TGC00
NOMESCO Finland
Bronchial lavation
4.7
25.9
90
198
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
10.2
25.8
51
51
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
264.1
25.7
26
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
94.7
25.7
28
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.2
25.6
140
458
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
25.4
886
6517
ZX121
NOMESCO Finland
Central venous catheter
14.8
25.2
42
29
C95.9
ICD-10 Finland
Leukaemia, unspecified
70.9
24.8
28
*
J02AC01
ATC
fluconazole; systemic
1.8
24.7
571
3706
L04AD01
ATC
ciclosporin; systemic
6.1
24.1
67
114
C91.2
ICD-10 Finland
Subacute lymphocytic leukemia
+∞
24.0
23
*
ZX114
NOMESCO Finland
Intramuscular
6.9
23.9
60
89
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
42.0
23.6
29
7
JN4AD
NOMESCO Finland
Body CT examination
2.6
23.4
188
783
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
23.4
425
2537
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
22.7
188
797
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
6.9
22.7
57
85
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
6.0
22.3
62
106
D70.82
ICD-10 Finland
Drug-induced neutropenia
6.1
22.2
61
103
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
63.3
21.9
25
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
21.8
344
1949
L03AA10
ATC
lenograstim; parenteral
116.4
21.6
23
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
21.6
583
3933
L01XE01
ATC
[U] imatinib; oral
23.4
21.3
30
13
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.8
21.2
91
246
Z2221
NOMESCO Finland
Medical doctor
1.7
21.0
507
3305
L04AA01
ATC
[U] ciclosporin; systemic
6.5
20.7
54
85
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.8
20.7
139
523
Z3231
NOMESCO Finland
Registered nurse
1.7
20.5
542
3623
121
Kela drug reimbursment
Severe hypofunction of sexual glands
6.0
20.5
57
98
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.5
20.2
162
671
C83.1
ICD-10 Finland
Mantle cell lymphoma
12.2
20.1
36
30
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
29.3
19.6
26
9
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
19.6
215
1046
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.2
19.4
211
1023
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
6.0
19.3
53
90
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
22.8
19.1
27
12
L01BB03
ATC
tioguanine; oral
+∞
18.8
18
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
18.7
230
1172
2301
FHL
Lumbar puncture in anesthesia or operating room
101.0
18.6
20
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
6.9
18.5
46
68
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
18.3
628
4478
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
21.9
18.2
26
12
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
17.9
359
2191
J02AC04
ATC
posaconazole; systemic
67.2
17.7
20
*
9670/3-C77.9
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph node, NOS
+∞
17.7
17
*
9831/3-C42.1
ICD-O-3
T-cell large granular lymphocytic leukemia of bone marrow
+∞
17.7
17
*
A02BC02
ATC
pantoprazole; systemic
1.5
17.7
1103
9040
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
8.4
17.5
38
46
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
17.2
574
4048
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.3
17.2
89
281
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
16.9
437
2872
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
17.6
16.9
26
15
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
17.6
16.9
26
15
ZXE00
NOMESCO Finland
One hour or less
1.6
16.8
693
5139
9823/3-C77.8
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of lymph nodes of multiple regions
+∞
16.7
16
*
122
Kela drug reimbursment
Aplastic anaemia
+∞
16.7
16
*
9837/3-C42.1
ICD-O-3
Precursor T-cell lymphoblastic leukemia of bone marrow
+∞
16.7
16
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
18.1
16.5
25
14
H02AB07
ATC
prednisone; oral
1.9
16.4
275
1579
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
15.8
147
661
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
10.5
15.7
30
29
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
15.6
122
500
C91.3
ICD-10 Finland
Prolymphocytic leukaemia of B-cell type
+∞
15.6
15
*
B74
ICPC
Malignant neoplasm blood other
17.3
15.6
24
14
Z2446
NOMESCO Finland
Social worker
2.4
15.6
142
631
A02BC01
ATC
omeprazole; systemic
1.6
15.4
511
3578
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
15.2
119
489
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
11.9
15.1
27
23
B59
ICD-10 Finland
Pneumocystosis
32.0
14.8
19
6
2AX04
NOMESCO Finland
NA
32.0
14.8
19
6
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
25.2
14.7
20
8
9109
FHL
Other measure in this category
21.2
14.7
21
10
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
14.4
343
2192
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
13.5
14.2
24
18
L04AA06
ATC
mycophenolic acid; systemic
4.8
14.1
46
97
B01.9
ICD-10 Finland
Varicella without complication
12.8
13.9
24
19
150
Kela drug reimbursment
Dasatinib
53.7
13.8
16
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
13.6
292
1808
C94.7
ICD-10 Finland
Other specified leukaemias
+∞
13.6
13
*
Z92.6
ICD-10 Finland
Personal history of chemotherapy for neoplastic disease
+∞
13.6
13
*
2AA01
NOMESCO Finland
NA
+∞
13.6
13
*
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
16.3
13.5
21
13
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
3.5
13.4
63
186
A04AA02
ATC
granisetron; systemic, transdermal
2.4
13.3
117
513
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
6.4
13.2
34
54
J01CA04
ATC
amoxicillin; systemic
1.5
13.1
1350
11896
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
15.1
13.1
21
14
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
19.2
12.9
19
10
L01XE06
ATC
[U] dasatinib; systemic
50.3
12.8
15
*
A07AA02
ATC
nystatin; oral
2.2
12.8
126
582
602
Kela drug reimbursment
Children's severe malnutrition
7.2
12.8
30
42
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.2
12.8
30
42
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
10.6
12.7
24
23
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
12.6
613
4640
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.8
12.6
82
302
ZXD05
NOMESCO Finland
Urgent procedure
1.5
12.6
533
3919
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
15.5
12.6
20
13
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
12.6
127
593
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
12.6
303
1941
3AA02
NOMESCO Finland
NA
+∞
12.5
12
*
C91.5
ICD-10 Finland
Adult T-cell lymphoma/leukaemia [HTLV-1-associated]
+∞
12.5
12
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
12.5
12
*
K03.66
ICD-10 Finland
Tooth plaque
2.2
12.5
132
632
B03XA01
ATC
erythropoietin; parenteral
5.8
12.4
34
59
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.1
12.3
148
747
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
12.2
197
1112
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.6
12.2
55
158
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
12.1
467
3360
B99
ICPC
Blood/lymph/spleen disease other
11.1
12.0
22
20
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
6.3
12.0
31
50
L01XX28
ATC
[D] imatinib; oral
47.0
11.9
14
*
J01DB01
ATC
cefalexin; oral
1.5
11.8
1379
12296
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.1
11.8
28
40
A41.8
ICD-10 Finland
Other specified sepsis
4.1
11.8
45
112
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
8.4
11.8
25
30
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
30.2
11.6
15
5
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
7.7
11.6
26
34
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
6.2
11.5
30
49
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
11.5
164
886
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
120.7
11.4
12
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.1
11.3
30
50
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.9
11.3
66
229
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.2
358
2460
FM2CE
NOMESCO Finland
NA
4.8
11.2
36
76
0388X
ICD-9 Finland
Septicaemia, Other specified septicaemias
25.2
11.1
15
6
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
6.7
11.0
27
41
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.7
10.9
73
277
L57.0
ICD-10 Finland
Actinic keratosis
1.8
10.8
205
1218
N02AA05
ATC
oxycodone; systemic
1.6
10.8
273
1766
ZXA00
NOMESCO Finland
Right side
1.5
10.7
462
3395
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
10.6
87
368
C03CA01
ATC
furosemide; systemic
1.4
10.5
572
4394
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
9.2
10.5
21
23
153
Kela drug reimbursment
Lenalidomid
9.2
10.5
21
23
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
4.4
10.5
37
86
J01MA02
ATC
ciprofloxacin; systemic
1.4
10.5
663
5240
2024A
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Leukaemic reticuloendotheliosis
+∞
10.4
10
*
5639
FHL
Other measure in this category
+∞
10.4
10
*
C83.0
ICD-10 Finland
Small cell B-cell lymphoma
+∞
10.4
10
*
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
+∞
10.4
10
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.5
10.3
77
311
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
6.4
10.3
26
41
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
18.9
10.3
15
8
B01AB05
ATC
enoxaparin; parenteral
1.4
10.2
500
3762
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
5.1
10.2
31
62
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
10.1
330
2272
306
Kela drug reimbursment
Erythropoietin and darbepoetin
11.3
10.1
18
16
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
11.3
10.1
18
16
A01AB09
ATC
miconazole; local oral
1.9
10.0
153
849
WW300
NOMESCO Finland
Transfer of autologic stem cells
10.1
10.0
19
19
E89.4
ICD-10 Finland
Postprocedural ovarian failure
40.3
10.0
12
*
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
6.3
9.8
25
40
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.8
642
5095
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.9
9.8
57
199
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.3
9.7
28
53
B01AB10
ATC
tinzaparin; parenteral
2.0
9.6
120
618
B03XA02
ATC
darbepoetin alfa; parenteral
3.2
9.6
49
157
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
9.5
187
1125
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.0
9.5
125
658
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
3.2
9.4
47
148
9800/3-C42.1
ICD-O-3
Leukemia, NOS, of bone marrow
+∞
9.4
9
*
K00.29
ICD-10 Finland
Other or indefinite deviation in the shape or size of the teeth
+∞
9.4
9
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
9.3
182
1091
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
9.1
183
1107
Z3226
NOMESCO Finland
Physiotherapist
1.5
9.1
315
2199
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
36.9
9.0
11
*
Z51.5
ICD-10 Finland
Palliative care
2.0
9.0
121
640
5BA08
NOMESCO Finland
NA
6.5
9.0
22
34
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
8.9
318
2233
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
12.6
8.9
15
12
Z31.6
ICD-10 Finland
General counselling and advice on procreation
8.0
8.8
19
24
L04AX04
ATC
lenalidomide; oral
8.6
8.8
18
21
JMA10
NOMESCO Finland
Transabdominal total splenectomy
6.3
8.8
22
35
R4110
NOMESCO Finland
Physiotherapy
1.4
8.8
433
3246
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
8.7
261
1757
ZX090
NOMESCO Finland
Other technic of radiotherapy
2.7
8.7
59
227
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
3.7
8.6
36
99
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
8.2
8.6
18
22
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
8.6
439
3316
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
3.8
8.5
34
90
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.2
8.5
82
378
L03AA14
ATC
lipegfilgrastim; parenteral
3.6
8.4
36
101
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
5.4
8.4
24
45
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
2.6
8.4
59
232
B34.9
ICD-10 Finland
Viral infection, unspecified
2.7
8.4
55
208
B84
ICPC
Unexplained abnormal white cells
90.4
8.4
9
*
WA010
NOMESCO Finland
Adjuvant whole body radiotherapy
90.4
8.4
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
8.4
483
3727
1XC15
NOMESCO Finland
NA
+∞
8.3
8
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.2
8.3
41
129
ZZR00
NOMESCO Finland
Flap of skin
2.7
8.3
55
210
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
8.6
8.3
17
20
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
3.5
8.3
36
103
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
14.5
8.2
13
9
L01XX05
ATC
hydroxycarbamide; oral
3.8
8.1
33
89
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.6
8.1
59
235
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.9
8.1
112
598
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
33.5
8.1
10
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.8
8.0
32
85
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.9
8.0
111
594
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.9
7.9
31
81
RS221
NOMESCO Finland
NA
3.5
7.9
35
102
120
Kela drug reimbursment
Hypogammaglobulinaemia
13.1
7.9
13
10
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
13.1
7.9
13
10
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
7.9
127
717
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.6
7.8
33
93
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.1
7.7
40
131
L01EA02
ATC
dasatinib; oral
45.2
7.7
9
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
7.4
7.7
17
23
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
7.6
76
358
J20.6
ICD-10 Finland
Acute bronchitis due to rhinovirus
18.4
7.6
11
6
5604
FHL
Vascular preparation or cannulation in the operating room
11.9
7.6
13
11
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
80.4
7.4
8
*
9801/3-C42.1
ICD-O-3
Acute leukemia, NOS, of bone marrow
80.4
7.4
8
*
B28
ICPC
Limited function/disability (B)
7.7
7.4
16
21
5609
FHL
Other measure in this category
+∞
7.3
7
*
9836/3-C42.1
ICD-O-3
Precursor B-cell lymphoblastic leukemia of bone marrow
+∞
7.3
7
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
9.4
7.3
14
15
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.8
7.3
43
154
L03AA04
ATC
NA
15.8
7.2
11
7
316
Kela drug reimbursment
Imatinib
15.8
7.2
11
7
Z08.2
ICD-10 Finland
Follow-up examination after chemotherapy for malignant neoplasm
15.8
7.2
11
7
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
5.8
7.2
19
33
J12.8
ICD-10 Finland
Other viral pneumonia
4.6
7.2
23
50
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
7.2
111
621
J35.1
ICD-10 Finland
Hypertrophy of tonsils
3.5
7.2
31
89
6753
FHL
Transabdominal splenectomy
30.1
7.1
9
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.8
7.1
22
46
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
4.4
7.1
24
55
0539X
ICD-9 Finland
Herpes zoster without mention of complication
20.1
7.1
10
5
4CJ01
NOMESCO Finland
NA
20.1
7.1
10
5
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
20.1
7.1
10
5
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
3.5
7.1
31
90
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.4
7.0
32
96
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
7.0
611
5011
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
6.9
148
912
H65.2
ICD-10 Finland
Chronic serous otitis media
3.4
6.9
31
92
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.5
6.9
30
87
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.2
6.9
69
327
YNB10
NOMESCO Finland
Collection of stem cells for transplant
13.8
6.9
11
8
M87.3
ICD-10 Finland
Other secondary osteonecrosis
13.8
6.9
11
8
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
4.1
6.9
25
62
B07.9
ICD-10 Finland
Verruca simplex
2.4
6.9
53
222
ZXA05
NOMESCO Finland
Left side
1.4
6.9
412
3185
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
3.7
6.9
28
77
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
6.7
6.8
16
24
K02.0
ICD-10 Finland
Caries limited to enamel
1.6
6.8
183
1202
WX110
NOMESCO Finland
Local anesthesy
1.3
6.8
1045
9255
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
9.3
6.8
13
14
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
2.5
6.8
51
210
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
40.2
6.8
8
*
1XX32
NOMESCO Finland
NA
22.6
6.7
9
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
2.2
6.7
62
284
J01FF01
ATC
clindamycin; systemic
1.4
6.6
407
3157
M05BA02
ATC
clodronic acid; systemic
5.9
6.6
17
29
L03AB05
ATC
interferon alfa-2b; parenteral
5.9
6.6
17
29
H35.6
ICD-10 Finland
Retinal haemorrhage
5.5
6.6
18
33
IEP04
NOMESCO Finland
Focused parenting intervention
12.3
6.6
11
9
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.6
565
4615
R05
ICD-10 Finland
Cough
1.4
6.6
290
2119
ZXC50
NOMESCO Finland
Cryotherapy
2.2
6.6
59
267
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
3.4
6.5
29
86
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.7
6.5
40
148
WF004
NOMESCO Finland
Palliative radiotherapy
2.7
6.5
40
148
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.8
6.5
108
618
BC00A
NOMESCO Finland
NA
70.1
6.4
7
*
WW402
NOMESCO Finland
Leucoferesis
14.3
6.4
10
7
B72
ICPC
Hodgkin Lymphoma
14.3
6.4
10
7
Z51.3
ICD-10 Finland
Blood transfusion (without reported diagnosis)
14.3
6.4
10
7
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
6.4
246
1753
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.3
535
4355
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
8.2
6.3
13
16
3AA13
NOMESCO Finland
NA
9.3
6.3
12
13
R4190
NOMESCO Finland
Nutritional therapy
2.2
6.3
60
280
L01EM01
ATC
idelalisib; oral
+∞
6.3
6
*
9670/3-C77.0
ICD-O-3
Malignant lymphoma, small B lymphocytic, NOS, of lymph nodes of head, face and neck
+∞
6.3
6
*
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
3.4
6.2
28
84
393
Kela drug reimbursment
Pomalidomide
26.8
6.2
8
*
324
Kela drug reimbursment
Dasatinib
26.8
6.2
8
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.2
6.2
30
95
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
7.0
6.2
14
20
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
5.8
6.1
16
28
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.0
6.1
70
350
ZQZ00
NOMESCO Finland
Treatment of several skin areas
4.7
6.1
19
41
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.1
276
2027
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
6.1
98
558
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.1
6.1
65
318
N02AX02
ATC
tramadol; systemic, rectal
1.3
6.0
668
5641

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_LYMPHOID_LEUKAEMIA – Lymphoid leukaemia

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).