Alcohol-induced acute pancreatitis

ALCOPANCACU

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K85.2
  • Hospital discharge: ICD-9 5770D|5770E
  • Cause of death: ICD-10 K85.2
  • Cause of death: ICD-9 5770D|5770E

2 out of 7 registries used, show all original rules.

1312

4. Check minimum number of events

None

1312

5. Include endpoints

None

1312

6. Filter based on genotype QC (FinnGen only)

1312

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K85

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13938 2274 11487
Only index persons 9836 1787 8049
Unadjusted period prevalence (%)
Whole population 0.28 0.07 0.32
Only index persons 0.26 0.07 0.31
Median age at first event (years)
Whole population 45.74 48.04 45.21
Only index persons 46.50 48.71 46.01

-FinnGen-

Key figures

All Female Male
Number of individuals 1312 242 1070
Unadjusted period prevalence (%) 0.40 0.08 0.47
Median age at first event (years) 48.87 48.67 48.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1168
Matched controls
11680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
16384.0
323.0
711
*
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
120.6
323.0
462
63
5770D
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA ALCOHOLICA NONHAEMORHAGICA]
+∞
323.0
445
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
59.3
319.7
374
92
K85
ICD-10 Finland
Acute pancreatitis
38.7
190.8
244
79
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
10.9
190.4
408
550
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
135.8
183.6
193
17
JN3AD
NOMESCO Finland
Abdominal CT examination
10.5
164.7
353
461
K86.1
ICD-10 Finland
Other chronic pancreatitis
66.4
160.8
185
33
JN3BD
NOMESCO Finland
Extensive abdominal CT
8.4
157.9
397
675
A09AA02
ATC
multienzymes (lipase, protease etc.)
26.9
142.3
200
89
K86.3
ICD-10 Finland
Pseudocyst of pancreas
102.7
140.0
152
17
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
93.4
133.8
147
18
R10.1
ICD-10 Finland
Pain localized to upper abdomen
6.3
123.2
383
839
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
30.1
122.2
166
64
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.1
106.0
596
2371
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.5
104.9
364
887
P15
ICPC
Chronic alcohol abuse
12.1
103.9
199
195
N07BB01
ATC
disulfiram; oral
8.1
100.0
245
372
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.8
99.8
279
514
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
12.4
95.6
180
169
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
27.5
93.6
130
53
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
150.9
92.6
97
7
5770F
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA ALCOHOLICA RECIDIVANS]
335.2
92.2
92
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
14.9
87.7
151
115
N02AX02
ATC
tramadol; systemic, rectal
3.4
84.0
702
3607
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
205.8
75.1
77
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
11.2
73.0
143
143
A10AE04
ATC
insulin glargine; parenteral
4.9
72.8
268
665
N05CF01
ATC
zopiclone; oral
3.2
70.8
506
2224
103
Kela drug reimbursment
Diabetes, insulin-treated
3.2
69.8
495
2160
N05BA01
ATC
diazepam; systemic, rectal
4.3
69.7
298
857
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.4
69.0
229
504
N06AX11
ATC
mirtazapine; oral
3.2
68.6
508
2278
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
12.3
68.4
128
116
N05AH04
ATC
quetiapine; oral
3.9
67.9
328
1052
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
15.7
67.6
113
79
F10.24
ICD-10 Finland
Alcohol depence active use
13.7
65.0
115
92
K85.8
ICD-10 Finland
Other acute pancreatitis
29.9
60.1
81
29
F10.09
ICD-10 Finland
Alcohol intoxication UNS
10.4
59.7
121
128
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
57.8
370
1457
A02BC02
ATC
pantoprazole; systemic
2.8
57.0
847
5643
N05BA04
ATC
oxazepam; oral
3.2
56.2
368
1467
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
56.0
436
1955
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.9
53.7
435
1988
P16
ICPC
Acute alcohol abuse
11.5
52.8
101
95
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
51.4
313
1172
5770E
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA ALCOHOLICAHAEMORRHAGICA]
+∞
50.4
48
*
R10.0
ICD-10 Finland
Acute abdomen
9.7
49.7
104
116
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
9.8
49.5
103
114
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
12.1
49.3
92
82
N05BA02
ATC
chlordiazepoxide; systemic
7.8
48.5
116
162
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.3
48.3
121
181
N06AB04
ATC
citalopram; systemic
3.0
47.9
336
1380
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
35.7
47.4
61
18
XF400
NOMESCO Finland
ECG with 12 standard connections
3.2
46.7
297
1136
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
13.1
44.8
80
65
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.4
44.7
143
294
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
26.7
44.1
61
24
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.7
43.9
217
683
K92.0
ICD-10 Finland
Haematemesis
8.6
43.7
98
123
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
43.2
606
3644
N05CD07
ATC
temazepam; oral
3.6
43.1
222
721
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.7
43.1
130
249
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.6
42.3
84
85
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
10.3
42.3
85
88
T90
ICPC
Diabetes non-insulin dependent
2.7
42.1
376
1768
K70.1
ICD-10 Finland
Alcoholic hepatitis
17.7
40.6
64
38
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.6
40.3
367
1739
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.5
39.7
123
243
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
38.6
396
1994
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
12.3
38.2
70
60
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
9.2
37.8
81
94
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
13.6
37.8
66
51
Z72.1
ICD-10 Finland
Alcohol use
10.5
37.7
75
76
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
12.4
37.2
68
58
UJK02
NOMESCO Finland
ERCP
8.2
35.9
82
106
TKC20
NOMESCO Finland
Catheterisation of bladder
4.1
35.8
152
415
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
35.0
239
938
K86.8
ICD-10 Finland
Other specified diseases of pancreas
127.2
34.9
37
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
19.1
34.7
53
29
K29.2
ICD-10 Finland
Alcoholic gastritis
40.5
34.5
43
11
N05AB01
ATC
dixyrazine; systemic
10.0
34.4
70
74
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
6.6
33.3
89
145
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.0
33.1
95
170
WX892
NOMESCO Finland
Monitored bed care
3.7
32.2
153
459
C07AA05
ATC
propranolol; systemic
2.7
32.0
261
1136
D02
ICPC
Abdominal pain epigastric
5.0
31.4
106
230
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.6
31.3
260
1144
N06AB10
ATC
escitalopram; oral
2.6
31.1
266
1187
ZXD05
NOMESCO Finland
Urgent procedure
2.2
31.1
416
2335
Z2446
NOMESCO Finland
Social worker
4.1
30.5
125
329
R4110
NOMESCO Finland
Physiotherapy
2.3
30.2
355
1867
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
11.0
30.2
58
55
T89
ICPC
Diabetes insulin dependent
5.2
30.1
98
204
N03AX16
ATC
pregabalin; oral
2.3
29.7
323
1635
ZXE00
NOMESCO Finland
One hour or less
2.1
29.5
477
2889
N06AX16
ATC
venlafaxine; oral
2.9
29.5
206
814
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.4
29.0
154
504
A06AD11
ATC
lactulose; oral
2.9
28.7
198
773
V03AA01
ATC
NA
5.8
28.6
83
151
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.5
28.4
141
437
A02BA02
ATC
ranitidine; systemic
2.5
27.9
266
1254
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
43.7
27.8
34
8
JLD12
NOMESCO Finland
Endoscopic drainage of pancreatic pseudocyst
102.6
27.8
30
*
A10BA02
ATC
metformin; oral
2.1
27.7
392
2231
E13
ICD-10 Finland
Other specified diabetes mellitus
26.1
27.6
38
15
K85.1
ICD-10 Finland
Biliary acute pancreatitis
21.7
27.5
40
19
SPAT1265
SPAT
Breathalyser
10.4
27.4
54
54
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
27.4
173
638
Z71.4
ICD-10 Finland
Alcohol abuse counselling and surveillance
16.3
27.4
44
28
E13.7
ICD-10 Finland
Other specified diabetes mellitus, with multiple complications
277.1
26.8
27
*
5770A
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA NONALCOHOLICA NONHAEMORRHAGICA]
46.9
26.6
32
7
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
5.9
26.4
76
137
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
26.4
684
4913
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
74.4
25.9
29
*
D01
ICPC
Abdominal pain/cramps general
3.3
25.7
139
460
N02BE01
ATC
paracetamol; systemic, rectal
2.3
25.6
989
8267
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.9
25.3
165
619
N06AB03
ATC
fluoxetine; oral
2.8
24.9
180
719
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
24.6
307
1636
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
4.5
24.1
88
207
N06AA12
ATC
doxepin; systemic
4.1
24.1
99
261
AA1AD
NOMESCO Finland
CT of head and brain
2.2
24.1
308
1656
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
6.9
24.0
61
93
Z3226
NOMESCO Finland
Physiotherapist
2.3
24.0
245
1188
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
23.9
437
2719
K86.0
ICD-10 Finland
Alcohol-induced chronic pancreatitis
68.9
23.9
27
*
J01DB01
ATC
cefalexin; oral
2.1
23.7
955
7927
JLC50
NOMESCO Finland
Atypical pancreatectomy
127.6
23.7
25
*
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
8.2
23.6
53
67
N05CF02
ATC
zolpidem; oral
2.4
23.4
230
1090
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.4
23.3
62
101
K92.1
ICD-10 Finland
Melaena
3.9
23.3
99
269
K70.0
ICD-10 Finland
Alcoholic fatty liver
12.8
23.2
41
33
R11
ICD-10 Finland
Nausea and vomiting
3.7
23.2
105
301
5772A
ICD-9 Finland
Diseases of pancreas, Cyst and pseudocyst of pancreas[CYSTA ET PSEUDOCYSTA PANCREATIS]
55.2
23.1
27
5
C03CA01
ATC
furosemide; systemic
2.1
22.8
312
1724
Z2221
NOMESCO Finland
Medical doctor
2.1
22.4
323
1822
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
22.3
349
2033
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
11.8
21.8
40
35
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
10.1
21.7
43
44
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.5
21.6
106
325
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
7.7
21.5
50
67
5353A
ICD-9 Finland
Gastritis and duodenitis, Alcoholic gastritis
51.0
21.2
25
5
A02BC05
ATC
esomeprazole; systemic
1.9
21.1
472
3121
F10.3
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state
19.9
20.9
31
16
WX002
NOMESCO Finland
Sedation and analgesia
2.2
20.4
250
1305
Z3231
NOMESCO Finland
Registered nurse
2.0
20.4
335
1975
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
20.4
562
3975
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
20.4
155
638
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.8
20.2
88
244
A02BC01
ATC
omeprazole; systemic
2.0
20.2
330
1942
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.2
20.1
112
376
EBA00
NOMESCO Finland
Extraction of tooth
1.9
20.0
412
2638
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.3
19.8
76
188
A03DA02
ATC
pitofenone and analgesics; systemic
9.6
19.7
40
43
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
19.6
137
534
JLB35
NOMESCO Finland
Transduodenal endoscopic extraction of foreign body from pancreatic duct
106.8
19.6
21
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
7.1
19.6
48
70
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
19.6
105
344
N05BE01
ATC
buspirone; oral
4.7
19.3
67
150
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
15.1
19.0
31
21
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
18.9
429
2823
S01.0
ICD-10 Finland
Open wound of scalp
2.8
18.8
132
515
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
7.6
18.8
44
60
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
13.7
18.8
32
24
5771C
ICD-9 Finland
Diseases of pancreas, Chronic pancreatitis[PANCREATITIS CHRONICA ALCOHOLICA RECIDIVANS]
101.7
18.6
20
*
S06.0
ICD-10 Finland
Concussion
2.6
18.5
144
599
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
18.5
250
1358
SPAT1262
SPAT
Handing over of treatment supplies
2.1
18.5
248
1342
F51.0
ICD-10 Finland
Nonorganic insomnia
2.5
18.4
160
707
N05AA02
ATC
levomepromazine; systemic
3.4
18.3
90
276
C08CA01
ATC
amlodipine; oral
1.8
18.3
411
2687
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
8.5
18.0
39
47
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.4
18.0
91
285
SPAT1227
SPAT
Substance abuse rehabilitation
10.9
18.0
34
32
W19
ICD-10 Finland
Unspecified fall
2.6
17.7
136
561
5770C
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA NONALCOHOLICA RECIDIVANS]
182.6
17.6
18
*
P01AB01
ATC
metronidazole; oral, rectal
1.8
17.5
407
2683
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.8
17.5
44
67
K86.2
ICD-10 Finland
Cyst of pancreas
13.4
17.5
30
23
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
29.3
17.5
23
8
N05BA12
ATC
alprazolam; oral
2.5
17.4
143
611
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.0
17.4
39
50
UJD02
NOMESCO Finland
Gastroscopy
3.8
17.4
75
207
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
8.3
17.3
38
47
N03AX12
ATC
gabapentin; oral
2.2
17.0
189
941
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
7.4
16.9
40
56
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
7.4
16.9
40
56
J01MA12
ATC
levofloxacin; systemic
2.0
16.8
243
1352
SPAT1254
SPAT
Administration of medicine
2.3
16.7
162
756
N06AB06
ATC
sertraline; oral
2.5
16.5
136
583
N02AA05
ATC
oxycodone; systemic
2.2
16.5
175
851
N07BA03
ATC
varenicline; oral
3.0
16.5
98
343
57709
ICD-8 Finland
Diseases of pancreas, Pancreatitis NUD
23.4
16.5
23
10
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
5.4
16.3
49
94
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
11.4
16.3
30
27
N05AH03
ATC
olanzapine; systemic
3.1
16.3
94
325
A10AE05
ATC
insulin detemir; parenteral
3.0
16.3
95
331
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
15.6
16.2
26
17
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.2
16.2
62
154
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.7
15.9
54
119
A10AE06
ATC
insulin degludec; parenteral
4.2
15.9
61
152
N06AX03
ATC
mianserin; oral
3.5
15.8
74
219
JAH33
NOMESCO Finland
Opening of laparostomy
33.9
15.8
20
6
F41.09
ICD-10 Finland
UNS Panic Syndrome
5.3
15.7
48
94
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
4.6
15.7
55
125
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
15.7
204
1084
S22.3
ICD-10 Finland
Fracture of rib
2.6
15.6
115
463
N06AA09
ATC
amitriptyline; systemic
2.5
15.6
126
532
Z71.8
ICD-10 Finland
Other specified counselling
1.9
15.3
243
1394
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.1
15.3
59
148
WX882
NOMESCO Finland
High dependency care
4.4
15.3
55
129
WX730
NOMESCO Finland
Conventional respirator
6.2
15.1
40
66
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
15.1
174
879
P01
ICPC
Feeling anxious/nervous/tense
2.8
15.1
101
385
E87.6
ICD-10 Finland
Hypokalaemia
4.4
15.0
55
131
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.1
14.9
182
940
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
32.1
14.8
19
6
D10
ICPC
Vomiting
3.6
14.7
67
194
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
14.6
453
3209
SPAT1247
SPAT
Outpatient detoxication and monitoring
11.0
14.5
27
25
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.4
14.5
71
218
N03AF01
ATC
carbamazepine; oral, rectal
3.2
14.5
78
257
5770B
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA NONALCOHOLICA HAEMORRHAGICA]
151.8
14.5
15
*
WYA20
NOMESCO Finland
Home visit
7.7
14.5
33
44
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
14.3
223
1266
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
14.3
64
183
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
8.8
14.3
30
35
WX872
NOMESCO Finland
Intensive care
2.8
14.3
92
342
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
9.3
14.2
29
32
P76
ICPC
Depressive disorder
3.2
14.2
77
255
B01AB05
ATC
enoxaparin; parenteral
1.8
14.1
327
2121
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
14.1
114
482
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.3
14.0
42
81
K70.4
ICD-10 Finland
Alcoholic hepatic failure
10.2
14.0
27
27
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
13.9
187
1001
A10BH01
ATC
sitagliptin; oral
2.3
13.9
134
620
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.3
13.9
71
226
E86
ICD-10 Finland
Volume depletion
5.0
13.8
44
91
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
13.5
430
3053
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
13.0
13.4
23
18
JAH00
NOMESCO Finland
Laparotomy
4.3
13.3
49
118
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.7
13.3
91
352
S18
ICPC
Laceration/cut
1.6
13.2
458
3321
N06AX05
ATC
trazodone; oral
4.6
13.1
45
101
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
3.5
13.1
61
181
M54.5
ICD-10 Finland
Low back pain
1.7
13.1
348
2346
WX110
NOMESCO Finland
Local anesthesy
1.6
13.0
754
6216
F32
ICD-10 Finland
Depressive episode
3.3
13.0
66
209
P03
ICPC
Feeling depressed
2.7
13.0
93
369
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.7
13.0
57
161
R53
ICD-10 Finland
Malaise and fatigue
1.9
12.9
207
1185
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.3
12.8
122
561
K05.31
ICD-10 Finland
Periodontitis pronounced
2.2
12.8
145
722
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.2
12.7
66
213
J01DA01
ATC
[U] cefalexin; systemic
1.6
12.6
670
5386
WX402
NOMESCO Finland
General anaesthesia
1.9
12.5
195
1103
JLT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pancreatic duct
+∞
12.5
12
*
E13.3
ICD-10 Finland
Other specified diabetes mellitus, with ophthalmic complications
+∞
12.5
12
*
N06AX21
ATC
duloxetine; oral
2.3
12.5
125
589
A01
ICPC
Pain general/multiple sites
2.7
12.5
85
327
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.4
12.4
112
501
T74.1
ICD-10 Finland
Physical abuse
5.7
12.4
35
63
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
12.4
268
1697
Y04.9
ICD-10 Finland
Assault by bodily force by unknown person
6.3
12.3
32
52
P18
ICPC
Medication abuse
9.8
12.3
24
25
A02BC03
ATC
lansoprazole; oral
1.7
12.2
313
2080
X57
ICD-10 Finland
Unspecified privation
4.3
12.2
45
109
K83.1
ICD-10 Finland
Obstruction of bile duct
6.5
12.2
31
49
XF600
NOMESCO Finland
Bloodpressure measurement
2.7
12.2
86
336
TK800
NOMESCO Finland
Hemodialysis
3.9
12.1
49
129
A10BB12
ATC
glimepiride; oral
2.5
12.1
97
410
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.5
12.1
57
171
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
12.1
57
171
Z72.8
ICD-10 Finland
Other problems related to lifestyle
18.3
12.1
18
10
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
12.0
126
607
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.8
12.0
76
281
M79.6
ICD-10 Finland
Pain in limb
1.6
11.9
352
2429
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.2
11.9
124
597
E13.1
ICD-10 Finland
Other specified diabetes mellitus, with ketoacidosis
47.2
11.9
14
*
L17
ICPC
Foot/toe symptom/complaint
1.8
11.9
245
1523
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
14.8
11.8
19
13
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
11.8
138
698
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
11.8
423
3071
S42.2
ICD-10 Finland
Fracture of upper end of humerus
3.6
11.7
53
154
W10
ICD-10 Finland
Fall on and from stairs and steps
2.9
11.7
69
244
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
12.7
11.6
20
16
F10.22
ICD-10 Finland
Alcohol dependence is currently on clinically controlled discontinuation medication
12.7
11.6
20
16
E13.4
ICD-10 Finland
Other specified diabetes mellitus, with neurological complications
65.6
11.6
13
*
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.3
11.6
114
534
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
11.6
230
1412
P74
ICPC
Anxiety disorder/anxiety state
3.9
11.4
46
121
TK810
NOMESCO Finland
Hemofiltration
8.0
11.4
25
32
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
11.3
97
425
M04AA01
ATC
allopurinol; systemic
1.9
11.1
170
956
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
8.1
11.1
24
30
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
8.1
11.1
24
30
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
7.2
11.1
26
37
N06AB05
ATC
paroxetine; oral
2.6
11.1
80
319
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.9
11.0
35
73
SPAT1240
SPAT
Therapeutic discussion
2.2
10.9
110
520
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
6.0
10.9
29
49
WX290
NOMESCO Finland
Other blockade of nerve
1.5
10.9
487
3711
2500X
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,NUD]
15.7
10.8
17
11
JN4AD
NOMESCO Finland
Body CT examination
2.3
10.7
101
464
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
10.7
117
575
5771D
ICD-9 Finland
Diseases of pancreas, Chronic pancreatitis[PANCREATITIS CHRONICA ALCOHOLICA NUD]
60.6
10.6
12
*
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
60.6
10.6
12
*
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
11.3
10.6
19
17
309
Kela drug reimbursment
Nalmefene and naltrexone
8.6
10.6
22
26
C03DA01
ATC
spironolactone; oral
2.1
10.5
120
601
N17.8
ICD-10 Finland
Other acute renal failure
6.9
10.4
25
37
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
10.4
124
632
G72.8
ICD-10 Finland
Other specified myopathies
5.0
10.4
32
65
57708
ICD-8 Finland
Diseases of pancreas, Pancreatitis acuta alia
16.2
10.4
16
10
2918A
ICD-9 Finland
Alcoholic psychoses, Other specified alcoholic psychosis
12.2
10.4
18
15
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
8.9
10.3
21
24
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
9.7
10.3
20
21
F10
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol
19.0
10.3
15
8
ZXD35
NOMESCO Finland
Usual procedure
3.0
10.2
58
198
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.7
10.2
71
275
N05AF03
ATC
chlorprothixene; systemic
3.6
10.2
45
129
K02.1
ICD-10 Finland
Caries of dentine
1.5
10.2
608
4911
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
10.2
286
1936
K29.7
ICD-10 Finland
Gastritis, unspecified
3.4
10.1
48
146
S97
ICPC
Chronic ulcer skin
2.7
10.0
70
273
JN4BD
NOMESCO Finland
Extensive body CT
2.0
10.0
133
707
K29.1
ICD-10 Finland
Other acute gastritis
5.9
10.0
27
47
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
16.9
9.9
15
9
F34.1
ICD-10 Finland
Dysthymia
3.3
9.9
48
149
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.2
9.8
51
166
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
9.8
340
2426
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
9.8
84
367
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
9.7
90
410
ZXA00
NOMESCO Finland
Right side
1.6
9.6
271
1831
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
9.6
89
407
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
7.2
9.5
22
31
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
9.5
63
239
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
5.0
9.5
29
59
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
7.6
9.4
21
28
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
9.4
191
1174
E13.2
ICD-10 Finland
Other specified diabetes mellitus, with renal complications
100.8
9.4
10
*
JAH30
NOMESCO Finland
Laparostomy
100.8
9.4
10
*
RS221
NOMESCO Finland
NA
5.2
9.4
28
55
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
6.3
9.4
24
39
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.4
9.4
27
51
C07AB07
ATC
bisoprolol; oral
1.5
9.3
489
3817
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.6
9.3
41
118
E87.2
ICD-10 Finland
Acidosis
8.8
9.3
19
22
RS222
NOMESCO Finland
NA
5.5
9.2
26
48
L86
ICPC
Back syndrome with radiating pain
2.5
9.2
69
282
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
9.2
290
2016
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
4.1
9.2
34
84
JLC10
NOMESCO Finland
Distal pancreatectomy
13.8
9.2
15
11
UJF32
NOMESCO Finland
Coloscopy
1.6
9.1
261
1770
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.8
9.1
57
208
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.8
9.1
57
208
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
9.1
141
792
N05AD03
ATC
melperone; systemic
5.7
9.1
25
45
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
9.1
170
1019
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
9.0
141
797
N19
ICD-10 Finland
Unspecified kidney failure
3.3
9.0
43
132
N06AA06
ATC
trimipramine; systemic
3.7
9.0
38
106
F60.9
ICD-10 Finland
Personality disorder, unspecified
5.8
8.9
24
42
P19
ICPC
Drug abuse
8.0
8.9
19
24
J96.0
ICD-10 Finland
Acute respiratory failure
6.4
8.8
22
35
K30
ICD-10 Finland
Functional dyspepsia
2.0
8.8
106
543
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
9.6
8.8
17
18
P29
ICPC
Psychological sympt/compl other
2.6
8.8
60
234
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.3
8.7
31
74
A04
ICPC
Weakness/tiredness general
2.0
8.7
114
605
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
8.7
290
2037
5780A
ICD-9 Finland
Gastro-intestinal haemorrhage, Haematemesis
50.4
8.7
10
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
6.7
8.7
21
32
X58
ICD-10 Finland
Exposure to other specified factors
1.8
8.7
165
995
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
8.7
753
6469
Z72.0
ICD-10 Finland
Tobacco use
3.2
8.7
44
142
F40.1
ICD-10 Finland
Social phobias
4.4
8.6
30
70
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.3
8.6
41
126
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
8.6
68
285
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
8.3
8.6
18
22
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
10.1
8.5
16
16
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.6
8.5
229
1528
A28
ICPC
Limited function/disability NOS
1.9
8.4
130
730
E14.1
ICD-10 Finland
Unspecified diabetes mellitus, with ketoacidosis
12.9
8.4
14
11
Y90.8
ICD-10 Finland
Blood alcohol level of 240 mg/100 ml or more
12.9
8.4
14
11
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.6
8.3
58
230
EBA30
NOMESCO Finland
Excision of root of tooth
2.3
8.3
73
327
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
2.8
8.3
50
182
E14
ICD-10 Finland
Unspecified diabetes mellitus
14.6
8.2
13
9
F05.9
ICD-10 Finland
Delirium, unspecified
4.1
8.2
30
74
F61.0
ICD-10 Finland
Mixed personality disorders
4.1
8.2
30
74
R95
ICPC
Chron obstructive pulmonary disease
3.1
8.2
42
137
A10AA02
ATC
NA
2.9
8.2
48
171
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
8.1
95
481
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.5
8.1
36
105
XPX00
NOMESCO Finland
Intraoperative angiography
17.3
8.1
12
7
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.8
8.1
32
85
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.6
8.1
56
221
Y09
ICD-10 Finland
Assault by unspecified means
9.0
8.0
16
18
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.2
8.0
29
71
K29.8
ICD-10 Finland
Duodenitis
5.9
8.0
21
36
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.2
8.0
81
387
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.1
8.0
41
134
GBB00
NOMESCO Finland
Tracheostomy
4.8
8.0
25
53
L02
ICPC
Back symptom/complaint
2.1
8.0
87
428
D06
ICPC
Abdominal pain localized other
2.3
7.9
72
325
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
5.2
7.9
23
45
-1
NOMESCO Finland
NA
1.5
7.8
328
2419
4019X
ICD-9 Finland
Essential hypertension, Unspecified
3.5
7.8
34
98
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.2
7.8
77
364
M10.9
ICD-10 Finland
Gout, unspecified
2.1
7.8
88
440
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
7.8
1000
9205
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
4.3
7.7
27
64
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
4.3
7.7
27
64
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.7
410
3176
JLB42
NOMESCO Finland
Transduodenal endoscopic dilatation of pancreatic duct
45.3
7.7
9
*
JLB12
NOMESCO Finland
Transduodenal endoscopic incision of pancreatic duct orifice
45.3
7.7
9
*
J01FF01
ATC
clindamycin; systemic
1.5
7.7
291
2098
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.9
7.7
45
160
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
2.4
7.7
62
264
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.2
7.6
75
351
S62.3
ICD-10 Finland
Fracture of other metacarpal bone
3.0
7.6
41
139
S10
ICPC
Boil/carbuncle
2.3
7.6
65
286
ZXE90
NOMESCO Finland
More than 22 hours
8.1
7.6
16
20
F10.02
ICD-10 Finland
Alcohol-related acute intoxication with other acute clinical complications
11.9
7.6
13
11
L76
ICPC
Fracture: other
3.4
7.6
35
106
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
7.6
177
1133
T51.0
ICD-10 Finland
Toxic effect: Ethanol
8.9
7.6
15
17
S00.0
ICD-10 Finland
Superficial injury of scalp
4.2
7.5
27
66
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.5
7.4
33
97
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
5.1
7.4
22
44
JLD00
NOMESCO Finland
Pancreaticojejunostomy
80.6
7.4
8
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.2
7.4
37
119
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.6
7.4
31
87
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
13.5
7.4
12
9
N06AX12
ATC
bupropion; oral
2.3
7.4
66
296
L03
ICPC
Low back symptom/complaint
1.6
7.4
219
1493
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
7.4
282
2037
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
4.4
7.4
25
58
WZA90
NOMESCO Finland
Other doctors statement
1.6
7.3
231
1594
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
7.3
116
659
6101
FHL
Exploratory laparotomy, includes possible biopases
10.9
7.3
13
12
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
7.3
578
4807
6727
FHL
Cystoenterostomy (includes pseudocyst)
+∞
7.3
7
*
6701
FHL
Exploration and possible biopsy
+∞
7.3
7
*
K86
ICD-10 Finland
Other diseases of pancreas
+∞
7.3
7
*
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
+∞
7.3
7
*
E13.0
ICD-10 Finland
Other specified diabetes mellitus, with coma
+∞
7.3
7
*
A46
ICD-10 Finland
Erysipelas
1.7
7.3
159
999
N05BA06
ATC
lorazepam; systemic, sublingual
2.4
7.3
57
240
EB1AA
SPAT
NA
2.6
7.2
51
204
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
7.2
66
302
R74
ICPC
Upper respiratory infection acute
1.6
7.2
228
1577
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
3.9
7.2
28
74
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.9
7.2
28
74
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.2
725
6285
R05
ICPC
Cough
1.6
7.2
191
1265
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.8
7.1
43
157
N06AG02
ATC
moclobemide; oral
2.5
7.1
53
217
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
7.1
156
980
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
6.6
7.1
17
26
K83.0
ICD-10 Finland
Cholangitis
5.1
7.1
21
42
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.6
7.1
205
1386
N05AD01
ATC
haloperidol; systemic
2.8
7.1
42
151
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
4.6
7.1
23
51
ZXA05
NOMESCO Finland
Left side
1.5
7.1
235
1643
E83.51
ICD-10 Finland
Hypocalcemia
8.8
7.1
14
16
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
4.4
7.0
24
56
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
10.1
7.0
13
13
WX110
SPAT
NA
2.5
7.0
52
211
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
4.7
7.0
22
47
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.8
7.0
42
153
D11
ICPC
Diarrhoea
1.9
7.0
99
542
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.2
7.0
71
339
SPAT1307
SPAT
Psychosocial counselling and guidance
2.5
7.0
53
221
ZY010
NOMESCO Finland
Hospital outpatient
2.5
7.0
53
221
A29
ICPC
General symptom/complaint other
1.9
7.0
102
563
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
7.0
66
306
K80
ICD-10 Finland
Cholelithiasis
6.4
6.9
17
27
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.9
6.9
102
565
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.1
6.9
35
114
N05CD08
ATC
midazolam; nasal, systemic
3.5
6.9
30
87
RS121
NOMESCO Finland
NA
7.6
6.9
15
20
C10AB05
ATC
fenofibrate; oral
3.3
6.9
32
98
F10.06
ICD-10 Finland
Alcohol-related acute intoxication with seizures
13.9
6.9
11
8
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
13.9
6.9
11
8
EBA00
SPAT
NA
3.7
6.9
28
77
K20
ICD-10 Finland
Oesophagitis
3.8
6.9
27
72
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
6.9
84
436
SPE90
NOMESCO Finland
Other fitting and preparation of partial tooth prosthesis
3.1
6.9
35
115
K72.9
ICD-10 Finland
Hepatic failure, unspecified
8.3
6.8
14
17
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.1
6.8
72
349
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.8
159
1019
K08.3
ICD-10 Finland
Retained dental root
1.9
6.7
89
475
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.0
6.7
37
128
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.7
6.7
21
45
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
4.1
6.7
24
59
A97
ICPC
No disease
1.7
6.7
130
790
L28
ICPC
Limited function/disability (L)
1.7
6.7
126
755
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.9
6.7
96
527
R03BB04
ATC
tiotropium bromide; inhalant
1.8
6.7
107
612
J01MA14
ATC
moxifloxacin; systemic
1.9
6.6
92
499
S82.6
ICD-10 Finland
Fracture of lateral malleolus
2.2
6.6
66
311
DQA10
NOMESCO Finland
Biopsy of larynx
6.5
6.6
16
25
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
5.2
6.6
19
37
9128
FHL
Open reduction and osteosynthesis
2.8
6.6
40
147
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.6
6.6
21
46
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
12.3
6.6
11
9
C09AA05
ATC
ramipril; oral
1.5
6.5
258
1872
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
6.5
43
166
R18
ICD-10 Finland
Ascites
3.5
6.5
28
81
L05
ICPC
Flank/axilla symptom/complaint
2.3
6.5
58
262
B86
ICD-10 Finland
Scabies
5.1
6.5
19
38
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
3.7
6.5
26
71
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.5
509
4198
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
5.4
6.5
18
34
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
6.5
119
710
S72.1
ICD-10 Finland
Pertrochanteric fracture
4.3
6.4
22
52
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
2.8
6.4
39
144
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
6.4
45
178
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
4.7
6.4
20
43
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.5
6.4
46
188
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
6.3
82
435
I81
ICD-10 Finland
Portal vein thrombosis
8.2
6.3
13
16
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
6.3
73
368
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.0
6.3
33
111
9690A
ICD-9 Finland
Poisoning by psychotropic agents, Antidepressants
18.1
6.3
9
5
N05AA03
ATC
promazine; systemic
18.1
6.3
9
5
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.4
6.3
51
221
C09AA02
ATC
enalapril; systemic
1.5
6.3
197
1356
S92.3
ICD-10 Finland
Fracture of metatarsal bone
2.9
6.3
36
127
6728
FHL
Drainage of abscess or pancreatitis (includes lavage)
+∞
6.3
6
*
WX290
SPAT
NA
3.2
6.3
30
95
K81.9
ICD-10 Finland
Cholecystitis, unspecified
4.3
6.2
21
49
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
6.2
105
608
Y07
ICD-10 Finland
Other maltreatment
4.8
6.2
19
40
29120
ICD-8 Finland
Alcoholic psychosis, Other alcoholic hallucinosis
26.8
6.2
8
*
5604
FHL
Vascular preparation or cannulation in the operating room
26.8
6.2
8
*
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
7.1
6.2
14
20
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.0
6.2
32
107
R55
ICD-10 Finland
Syncope and collapse
1.8
6.2
103
597
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
6.3
6.2
15
24
S01.7
ICD-10 Finland
Multiple open wounds of head
5.4
6.2
17
32
QAB00
NOMESCO Finland
Suture of skin of head or neck
3.4
6.1
27
80
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.6
6.1
42
167
5CM18
NOMESCO Finland
NA
7.7
6.1
13
17
M54
ICD-10 Finland
Dorsalgia
1.8
6.1
104
605
A02BA04
ATC
nizatidine; systemic
1.9
6.1
82
441
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.1
357
2792
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.1
102
591
F10.05
ICD-10 Finland
Alcohol-related acute intoxication with coma
12.6
6.1
10
8
C10AA01
ATC
simvastatin; oral
1.4
6.1
434
3513
L08
ICPC
Shoulder symptom/complaint
1.6
6.1
181
1234
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
2.4
6.1
49
210
205
Kela drug reimbursment
Chronic hypertension
1.5
6.0
265
1963
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
2.5
6.0
46
191
J37.0
ICD-10 Finland
Chronic laryngitis
2.7
6.0
37
138
Y04.0
ICD-10 Finland
Assault by bodily force by spouse or partner
10.1
6.0
11
11
F10.52
ICD-10 Finland
Psychotic alcohol hallucination
10.1
6.0
11
11
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.0
112
671
K07
ICPC
Swollen ankles/oedema
2.6
6.0
41
163

Mortality – FinRegistry

Association

Association between endpoint ALCOPANCACU and mortality.

Females

Parameter HR [95% CI] p-value
ALCOPANCACU 4.5 [2.55, 7.94] < 0.001
Birth year 0.994 [0.99, 1.0] 0.196

During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 815 females with ALCOPANCACU died.

Males

Parameter HR [95% CI] p-value
ALCOPANCACU 3.965 [3.18, 4.95] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 456 out of 3511 males with ALCOPANCACU died.

Mortality risk

Mortality risk for people of age

years, who have ALCOPANCACU.

N-year risk Females Males
1 0.291% 0.681%
5 3.029% 4.904%
10 6.421% 12.006%
15 12.055% 21.085%
20 20.524% 33.046%

Relationships between endpoints

Index endpoint: ALCOPANCACU – Alcohol-induced acute pancreatitis

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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