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Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

C3_MGUS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 D47.2
  • Hospital discharge: ICD-10 D47.2
  • Hospital discharge: ICD-9 2731
  • Cause of death: ICD-10 D47.2
  • Cause of death: ICD-9 2731
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9765
  • Cancer registry: Behaviour codes 1

4 out of 7 registries used, show all original rules.

1687

4. Check minimum number of events

None

1687

5. Include endpoints

None

1687

6. Filter based on genotype QC (FinnGen only)

1687

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1687 759 928
Unadjusted period prevalence (%) 0.34 0.26 0.41
Median age at first event (years) 70.09 68.02 71.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
230
103
25.70
320.58
1.2
1.1
—
—
—
0
0
783
535
26.45
307.65
7.5
1.3
2.8
3.1
g/l
9.15
576
416
917
325
60.63
307.65
6.8
1.3
—
—
—
0
0
481
189
35.20
307.65
1.4
1.5
—
—
—
0
0
903
2085
8.17
307.65
4.3
1.3
3.4
2.7
g/l
3.50
751
1154
830
579
27.25
307.65
7.4
1.3
3.9
3.9
g/l
0.09
563
410
825
1785
8.09
307.65
3.8
2.1
1.7
1.8
%
0.43
758
1546
1066
444
63.51
307.65
7.6
1.3
54.9
47.3
mg/l
0.24
859
356
833
579
27.44
307.65
7.3
1.3
6.9
7.6
g/l
10.15
591
422
820
642
23.91
307.65
4.9
1.3
3.4
1.1
g/l
18.05
728
581
336
45
92.99
307.65
2.0
1.0
—
—
—
0
0
550
123
65.86
307.65
2.9
1.2
—
—
—
0
0
1292
1185
43.29
307.65
8.8
1.5
69.6
66.6
g/l
21.48
1226
1051
953
272
79.23
307.65
2.2
1.2
—
—
—
0
0
1064
430
65.30
307.65
7.4
1.3
6.1
1.4
ratio
3.77
92
35
769
545
25.09
307.65
7.4
1.3
11.9
10.5
g/l
5.11
622
455
1294
1028
50.74
307.65
8.5
1.3
—
—
—
0
0
1069
445
63.85
307.65
7.6
1.4
67.9
48.3
mg/l
2.96
857
356
598
461
19.55
307.65
7.6
1.3
38.6
37.3
g/l
3.57
523
381
879
804
21.74
307.65
6.1
2.1
12.7
11.0
g/l
7.49
813
728
255
101
29.57
307.65
2.2
1.8
0.3
0.9
g/24h
—
9
7
683
1348
7.83
307.65
3.8
2.1
66.2
67.9
e9/l
0.49
535
1036
1403
6307
8.27
288.64
12.3
5.3
0.6
0.6
e9/l
1.89
1286
5354
1403
6346
8.19
285.33
12.3
5.3
0.0
0.0
e9/l
0.04
1287
5402
1328
5729
7.19
284.35
12.5
5.5
0.7
0.7
%
0.47
1272
5249
1138
4303
6.05
284.02
10.8
5.3
—
—
—
0
0
1347
5922
7.32
281.04
13.0
5.8
9.3
8.9
%
4.92
1291
5435
1408
6448
8.16
280.45
12.4
5.4
1.9
1.8
e9/l
0.68
1304
5568
1343
5900
7.26
280.06
12.5
5.5
2.9
3.0
%
0.56
1286
5396
1414
6570
8.12
274.80
12.9
5.4
0.2
0.2
e9/l
3.22
1306
5666
1350
6019
7.22
274.79
12.8
5.7
27.9
26.4
%
4.05
1295
5492
1338
5963
7.01
270.99
12.0
5.5
56.6
58.4
%
5.67
1279
5475
191
84
25.51
267.28
1.9
1.2
—
—
—
0
0
1436
7023
8.02
255.20
19.3
6.1
3.9
4.4
e9/l
11.56
1330
5996
1428
6993
7.79
251.94
16.5
5.5
1.2
1.2
mmol/l
0.18
1200
5864
197
112
19.78
246.87
1.1
1.1
—
—
—
0
0
1048
4025
5.23
246.66
11.5
3.2
7.4
7.4
ph
1.24
250
700
654
1778
5.37
234.09
9.1
4.9
1.1
1.0
mmol/l
4.02
614
1624
119
11
116.32
233.26
3.3
1.2
—
—
—
0
0
1322
6314
6.06
231.70
13.7
5.0
1.2
1.2
mmol/l
1.95
1264
5546
1253
5803
5.51
225.94
8.6
3.7
33.9
35.1
g/l
10.80
1180
5295
291
379
9.07
216.05
1.5
1.3
—
—
—
0
0
652
1877
5.03
215.39
4.3
2.5
22.1
22.3
%
0.12
582
1559
382
695
6.81
209.88
2.1
1.6
1.4
1.5
g/l
0.76
319
593
668
2014
4.84
207.15
4.1
2.4
2.2
2.3
g/l
4.99
639
1843
948
3726
4.53
206.80
5.1
2.5
2551.2
7684.8
umol/l
3.95
858
3136
701
2198
4.75
206.67
4.1
2.4
11.9
12.7
umol/l
2.11
673
2004
101
11
97.60
194.10
3.5
1.2
—
—
—
0
0
1271
6504
4.87
186.37
9.8
3.7
11.1
12.3
umol/l
2.33
1232
6072
144
77
20.35
184.81
1.9
1.4
2125.8
1815.6
ml
0.48
13
21
402
912
5.47
172.74
1.7
1.5
—
—
—
0
0
411
961
5.33
170.43
1.8
1.4
—
—
—
0
0
182
192
10.50
157.52
1.4
1.1
—
—
—
0
0
428
1124
4.76
153.07
1.8
1.5
—
—
—
0
0
951
4420
3.64
148.61
4.9
2.1
2.3
2.4
mmol/l
3.85
834
3614
280
539
6.03
142.62
1.4
1.3
—
—
—
0
0
1046
5276
3.59
141.21
4.8
2.8
191.1
140.5
ug/l
4.91
971
4759
575
1983
3.88
140.82
4.2
2.5
0.8
0.8
mmol/l
4.44
539
1805
832
3682
3.49
137.92
3.0
2.3
3.1
3.0
mg/l
0.28
728
3105
387
1025
4.60
135.70
6.8
3.6
0.9
0.8
%
0.20
177
228
90
34
27.91
132.03
1.4
1.1
—
—
—
0
0
852
3915
3.38
131.17
6.9
4.0
—
—
—
0
0
490
1592
3.93
129.61
1.4
1.3
558.6
591.5
titre
0.13
111
382
639
2542
3.44
123.11
9.9
4.2
—
—
—
0
0
356
985
4.31
116.70
7.0
3.7
0.1
0.1
%
1.04
161
210
344
939
4.35
114.69
6.7
3.5
0.6
0.6
%
0.02
129
174
1485
10106
4.92
113.51
16.4
5.4
82.7
77.5
u/l
2.62
1453
9287
229
454
5.68
112.05
2.2
2.5
0.3
0.3
g/l
0.31
115
138
185
301
6.78
110.76
3.9
2.5
1.9
1.7
mg/l
1.63
170
261
1019
5577
3.09
109.88
22.2
9.0
0.0
0.0
e9/l
0.91
887
4529
381
1157
3.96
109.35
5.4
3.6
107.0
93.0
ng/l
1.71
331
970
394
1237
3.85
107.66
10.9
6.3
12.5
11.3
mmol/l
2.17
377
1162
664
2936
3.08
103.80
12.5
4.8
—
—
—
0
0
194
355
6.04
103.12
2.0
1.6
1.2
1.2
g/l
0.23
186
332
192
348
6.10
103.07
2.1
1.6
0.2
0.2
g/l
1.08
183
328
254
605
4.77
100.11
1.2
1.6
1.4
16.3
u/ml
—
5
19
325
941
4.04
99.10
7.2
3.8
1.0
0.5
%
0.28
130
187
537
2194
3.12
95.13
3.1
1.9
30.2
30.1
s
0.17
518
2109
804
4130
2.81
92.81
4.9
3.1
30.5
91.9
e6/l
2.44
672
3194
152
247
6.66
90.76
1.4
1.2
51.4
21.3
u/l
4.28
147
214
752
3775
2.79
90.12
4.7
3.0
0.5
0.5
e6/l
0.10
623
2866
1250
8172
3.04
88.88
9.5
4.3
6.7
6.9
mmol/l
3.30
1211
7641
874
4800
2.70
86.73
5.8
3.5
70.1
113.2
e6/l
1.70
695
3441
744
3786
2.73
85.81
2.2
1.6
20.9
20.3
nmol/l
0.46
668
3122
1415
10024
3.55
85.42
8.4
4.2
30.7
13.1
mm/h
92.08
1337
9157
643
3060
2.78
84.32
6.1
3.5
84.8
84.0
%
0.30
624
2970
726
3721
2.67
81.57
4.5
2.2
—
—
—
0
0
115
156
7.84
80.84
4.2
2.9
1.5
1.6
%
0.05
83
111
588
2724
2.78
80.59
4.1
2.6
514.5
545.9
mosm/kgh2o
3.60
522
2277
713
3646
2.66
80.16
4.7
3.0
—
—
—
0
0
616
2929
2.74
80.16
3.6
2.4
4.1
5.2
e6/l
1.72
550
2542
659
3273
2.66
78.22
2.1
1.8
1239.0
1156.1
nmol/l
1.15
516
2434
943
5567
2.57
77.83
3.3
2.2
80.5
79.0
nmol/l
0.85
850
4790
565
2605
2.76
77.69
4.2
2.2
2.5
2.5
mmol/l
5.81
498
2224
949
5652
2.55
76.36
6.4
3.7
—
—
—
0
0
73
57
13.34
76.32
2.8
2.5
1.2
1.1
e9/l
0.57
47
36
989
6011
2.56
76.10
14.7
11.3
1.3
1.4
inr
3.99
295
1691
66
44
15.57
75.38
2.4
2.9
17.4
15.2
%
0.33
26
21
874
5033
2.53
75.25
4.0
3.1
2287.4
1663.9
ng/l
1.79
796
4332
70
54
13.48
73.68
1.5
1.3
1.7
0.1
g/l
—
9
6
354
1301
3.18
73.22
3.8
2.3
8.9
8.9
umol/l
0.01
301
1124
254
768
3.72
71.52
2.4
1.4
3.8
3.6
ug/l
0.11
204
580
1020
6442
2.48
69.89
2.7
2.1
95.0
93.4
pmol/l
0.49
610
3257
307
1118
3.13
63.87
9.4
6.8
—
—
—
0
0
115
202
6.04
63.23
4.1
2.9
3.8
4.4
e9/l
1.50
115
202
117
209
5.94
63.23
4.4
3.0
56.4
58.5
%
0.84
117
209
1257
8972
2.57
62.37
6.7
4.7
294.7
2753.4
e6/l
2.08
15
142
712
4003
2.35
61.09
2.5
1.7
—
—
—
0
0
101
165
6.45
59.68
1.5
1.3
—
—
—
0
0
301
1128
3.03
59.29
11.5
2.9
1.2
1.2
mmol/l
0.33
288
946
138
307
4.81
58.28
2.3
2.0
12.3
12.4
mg/l
0.03
123
279
51
35
14.99
57.22
1.3
1.5
—
—
—
0
0
151
369
4.40
56.70
1.3
1.3
13.7
20.7
iu/ml
—
5
7
413
1874
2.59
56.15
2.3
2.0
—
—
—
0
0
553
2882
2.37
55.47
3.9
2.2
—
—
—
0
0
98
168
6.13
55.17
1.5
1.8
0.6
1.1
g/l
2.66
70
131
196
591
3.62
54.86
2.1
1.7
2.5
1.6
ug/l
0.55
170
512
1269
9377
2.43
53.63
6.8
4.4
—
—
—
0
0
287
1113
2.90
52.75
2.3
1.8
353.2
360.7
nmol/l
0.22
263
991
437
2118
2.43
51.02
4.1
2.9
2.2
2.4
e6/l
0.22
251
1174
130
309
4.47
50.48
5.6
3.6
—
—
—
0
0
53
48
11.37
50.36
3.2
1.5
589.9
963.8
e6/l
1.29
20
17
85
140
6.34
49.76
1.5
1.3
102.3
113.2
u/ml
0.54
23
21
66
82
8.34
49.75
2.0
1.5
—
—
—
0
0
39
21
18.99
49.25
2.0
3.8
—
—
—
0
0
75
111
7.02
48.60
1.5
1.4
7.8
7.0
g/l
0.51
57
81
75
111
7.02
48.60
1.6
1.4
—
—
—
0
0
75
111
7.02
48.60
1.5
1.4
0.5
0.4
g/l
0.48
57
80
75
111
7.02
48.60
1.5
1.4
2.8
3.0
g/l
0.31
56
80
729
4444
2.13
48.23
4.3
3.3
—
—
—
0
0
335
1485
2.57
47.00
6.1
3.3
7.4
7.4
ph
—
6
10
90
166
5.67
46.91
1.1
1.1
—
—
—
0
0
324
1416
2.59
46.80
6.3
3.2
1.6
2.0
mmol/l
1.02
267
1134
324
1423
2.58
46.29
6.3
3.2
5.9
5.8
kpa
0.56
310
1368
451
2301
2.31
46.24
3.8
2.7
1.1
1.4
e6/l
0.66
267
1347
74
116
6.63
45.43
4.8
2.9
51.4
57.9
%
0.87
41
73
260
1042
2.77
44.48
2.3
1.9
0.2
0.2
g/l
1.29
229
934
414
2068
2.33
44.38
1.4
1.3
53.8
41.3
iu/ml
0.62
138
635
241
930
2.86
44.28
1.5
1.1
—
—
—
0
0
193
668
3.13
43.00
6.9
3.6
23.5
24.2
mmol/l
2.10
177
589
103
232
4.66
42.70
4.7
2.9
—
—
—
0
0
503
2777
2.16
41.86
2.0
1.6
1.4
1.3
mg/l
0.10
419
2159
103
236
4.58
41.80
1.2
1.4
—
—
—
0
0
149
455
3.50
40.62
1.4
1.2
4.1
0.9
u/ml
0.60
11
41
368
1830
2.29
39.35
1.3
1.2
—
—
—
0
0
116
306
4.00
39.13
7.0
4.2
2.7
2.8
mmol/l
0.14
88
205
1541
13097
3.04
38.62
38.9
14.4
25.2
25.1
mg/l
0.04
1439
10388
71
133
5.53
36.36
1.2
1.1
—
—
—
0
0
723
4730
1.92
36.30
2.5
2.2
230.8
232.6
u/l
0.01
694
4407
856
5922
1.90
36.18
5.5
4.1
51.7
103.9
ng/l
0.92
711
4510
124
365
3.59
35.68
7.4
4.0
7.4
7.4
ph
0.03
112
300
266
1197
2.45
35.43
7.4
5.7
1.4
1.5
mmol/l
0.76
259
1151
924
6583
1.89
35.35
5.5
3.8
0.0
0.0
estimate
0.00
226
1144
336
1676
2.25
35.30
6.8
6.1
11.3
11.4
kpa
0.05
324
1593
336
1676
2.25
35.30
6.9
6.1
5.1
5.1
kpa
0.06
324
1595
334
1670
2.25
34.85
6.9
6.1
1.2
1.3
mmol/l
0.09
282
1277
933
6687
1.88
34.83
5.5
3.8
0.0
0.0
estimate
1.08
221
1122
923
6598
1.88
34.69
7.3
5.1
0.0
0.0
estimate
0.50
230
1150
272
1248
2.41
34.66
1.3
1.3
—
—
—
0
0
438
2467
2.05
33.43
1.3
1.2
0.9
1.9
u/ml
2.70
91
626
125
386
3.42
33.39
1.5
1.4
—
—
—
0
0
313
1552
2.25
33.19
2.1
1.8
—
—
—
0
0
505
2999
1.98
33.15
5.6
4.1
195.2
527.6
ng/l
2.56
450
2554
43
53
8.30
32.56
2.7
2.4
41.1
42.5
%
—
9
23
45
59
7.81
32.38
1.2
1.1
—
—
—
0
0
46
62
7.60
32.34
2.5
2.2
—
—
—
0
0
340
1760
2.17
32.33
7.7
5.6
103.8
104.2
mmol/l
0.66
335
1704
375
2017
2.10
32.28
1.3
1.2
18.6
13.3
u/ml
0.38
102
728
23
10
23.30
31.50
3.1
2.0
65.3
196.0
e6/l
—
15
5
1289
10432
2.00
31.42
46.0
17.3
14.5
13.8
%
44.18
1283
10124
641
4180
1.86
31.28
3.0
2.3
59.0
59.2
u/l
0.03
597
3820
83
203
4.25
30.96
1.4
1.1
—
—
—
0
0
148
529
2.97
30.93
1.3
1.2
—
—
—
0
0
236
1067
2.41
30.88
2.5
2.1
32.9
34.3
u/l
0.24
194
881
124
400
3.27
30.87
2.7
1.8
21.8
21.3
s
0.58
117
351
302
1525
2.19
30.41
7.2
6.2
94.5
94.9
%
0.43
293
1463
74
168
4.56
30.34
1.0
1.0
—
—
—
0
0
1021
7721
1.82
30.13
3.8
3.0
63.5
50.9
u/l
2.58
932
6987
67
141
4.91
30.10
1.4
1.1
263.3
292.2
u/ml
0.27
40
79
279
1382
2.22
29.40
7.5
6.6
114.3
121.7
g/l
7.45
272
1332
104
313
3.48
28.89
4.3
2.4
14.4
16.2
%
3.72
60
167
60
119
5.19
28.85
5.6
3.2
—
—
—
0
0
97
283
3.58
28.24
2.3
1.8
2602.9
107.8
u/ml
0.66
79
227
177
729
2.60
28.17
1.3
1.3
28.6
53.8
au/ml
—
5
32
118
392
3.16
27.95
3.6
3.6
—
—
—
0
0
62
131
4.88
27.72
1.5
1.6
—
—
—
0
0
124
433
3.01
26.96
1.6
1.5
—
—
—
0
0
702
4875
1.75
26.62
5.2
3.2
6378.6
176.0
mg/l
19.75
533
3089
144
551
2.76
26.47
2.7
2.2
680.8
941.2
ug/l
0.26
132
515
170
709
2.55
26.32
8.4
7.7
24.3
24.4
mmol/l
0.05
163
641
1222
9978
1.82
25.59
4.4
3.8
15.0
15.0
pmol/l
0.62
1110
8875
70
175
4.13
25.37
1.6
1.5
28.6
27.5
g/l
0.25
56
154
290
1543
2.06
25.13
3.5
3.1
318.2
236.1
ng/l
1.62
261
1428
97
310
3.26
24.49
1.3
1.1
217.1
92.0
titre
—
7
20
31
9
35.05
24.31
1.1
1.0
—
—
—
0
0
168
733
2.43
23.56
7.9
8.5
—
—
—
0
0
66
168
4.05
23.35
4.8
6.6
11.6
12.2
mg/l
0.55
56
154
54
118
4.69
23.21
1.6
1.5
—
—
—
0
0
234
1193
2.12
22.58
5.0
2.6
4.8
4.5
kpa
1.25
222
1143
44
84
5.35
22.08
1.2
1.2
—
—
—
0
0
198
957
2.21
21.85
5.1
3.5
7.4
7.4
ph
0.05
50
118
110
410
2.80
21.22
4.0
3.2
25.1
25.2
mmol/l
0.07
98
358
199
975
2.18
21.21
5.2
3.5
5.2
5.2
kpa
0.05
186
888
96
333
3.00
21.10
1.5
1.2
3.0
3.4
u/ml
0.15
15
33
89
297
3.11
20.91
3.9
2.8
—
—
—
0
0
208
1047
2.13
20.67
7.1
3.9
—
—
—
0
0
99
355
2.90
20.51
1.5
1.2
24.0
49.6
u/ml
0.68
12
21
61
162
3.87
20.38
1.0
1.1
—
—
—
0
0
55
137
4.12
20.05
1.8
1.5
—
—
—
0
0
55
137
4.12
20.05
1.8
1.5
—
—
—
0
0
55
137
4.12
20.05
1.8
1.5
—
—
—
0
0
55
137
4.12
20.05
1.8
1.5
—
—
—
0
0
176
844
2.21
19.75
3.8
3.0
4.0
4.2
e9/l
0.45
114
585
1549
14032
2.27
19.40
40.8
17.6
139.0
139.7
mmol/l
23.49
1538
13616
1317
11322
1.74
19.35
38.2
16.0
36.4
39.0
%
15.75
812
6997
1551
14065
2.27
19.25
42.4
17.7
4.0
4.0
mmol/l
0.29
1540
13626
450
2975
1.70
19.01
1.5
1.3
—
—
—
0
0
63
181
3.58
18.80
3.1
3.0
—
—
—
0
0
198
1019
2.07
18.49
4.6
4.4
—
—
—
0
0
1394
12232
1.80
18.44
5.6
4.7
2.0
2.1
mu/l
0.61
1274
10917
41
87
4.81
18.27
1.0
1.2
—
—
—
0
0
57
156
3.75
18.26
1.7
1.5
1014.3
1665.1
e6/l
0.96
38
110
83
289
2.97
18.13
1.3
1.2
—
—
—
0
0
671
4957
1.59
17.96
4.0
3.2
6.5
7.3
mmol/l
5.91
570
4112
54
146
3.79
17.61
1.3
1.3
48.3
65.3
u/ml
—
7
7
1542
14034
2.15
17.58
22.6
9.4
24.3
24.8
u/l
0.49
1519
13330
144
667
2.27
17.54
1.5
1.2
154.5
231.6
u/ml
1.15
136
609
92
347
2.75
17.36
1.4
1.4
263.6
289.5
ug/g
0.57
55
212
231
1285
1.92
17.25
2.1
2.1
125.8
169.5
ug/g
1.56
189
993
1496
13487
1.96
17.25
32.4
14.2
—
—
—
0
0
91
344
2.74
17.10
3.5
2.2
118.1
131.8
g/l
5.40
73
254
476
3268
1.64
17.09
4.7
3.8
—
—
—
0
0
75
258
3.00
16.75
1.2
1.3
56.5
64.4
mmol/l
1.22
59
206
52
143
3.72
16.56
1.7
1.5
13291.0
78396.5
e6/l
0.79
32
82
78
277
2.90
16.46
1.5
1.3
355.8
619.4
e6/l
0.27
68
232
78
277
2.90
16.46
1.5
1.3
14.4
38.2
e6/l
0.53
63
221
1150
9706
1.58
16.45
5.6
4.2
—
—
—
0
0
254
1484
1.84
16.24
1.7
1.4
—
—
—
0
0
34
69
5.01
15.97
1.1
1.1
—
—
—
0
0
252
1483
1.82
15.71
11.7
3.6
—
—
—
0
0
135
638
2.21
15.65
1.4
1.3
—
—
—
0
0
17
16
10.72
15.55
2.4
1.5
—
—
—
0
0
65
215
3.10
15.54
3.2
2.7
—
—
—
0
0
20
24
8.42
15.40
1.1
1.0
—
—
—
0
0
31
60
5.24
15.35
1.4
1.2
—
—
—
0
0
113
501
2.35
15.23
2.7
1.8
—
—
—
0
0
33
69
4.86
14.98
1.2
1.4
—
—
—
0
0
35
78
4.56
14.74
1.3
1.1
52.9
37.8
mg/l
1.04
28
66
674
5160
1.51
14.46
5.2
4.0
26.2
8.2
mg/mmol
6.81
480
3270
34
76
4.55
14.27
1.1
1.1
350.6
265.5
mg/l
1.24
29
68
40
103
3.95
14.00
1.1
1.1
—
—
—
0
0
178
976
1.92
13.78
4.9
2.9
117.9
130.7
g/l
12.27
171
944
1558
14462
2.01
13.25
55.0
21.1
242.5
241.2
e9/l
0.25
1545
13960
45
131
3.50
13.22
1.9
1.6
—
—
—
0
0
1558
14464
2.01
13.22
54.7
21.0
93.8
91.7
fl
37.92
1551
14148
1558
14465
2.01
13.20
54.6
21.0
30.9
30.5
pg
12.04
1550
14150
1558
14466
2.01
13.18
55.0
21.1
6.9
6.8
e9/l
0.49
1542
13899
1558
14466
2.01
13.18
54.8
21.1
4.0
4.5
e12/l
122.56
1542
13899
469
3377
1.54
13.16
5.7
3.5
—
—
—
0
0
1558
14468
2.01
13.14
55.3
21.2
123.4
135.0
g/l
128.49
1549
14157
44
128
3.50
12.95
1.2
1.1
—
—
—
0
0
72
284
2.60
12.49
3.2
2.4
32.6
34.1
umol/l
0.22
59
240
151
812
1.94
12.37
2.6
2.5
—
—
—
0
0
32
77
4.22
12.27
1.6
1.3
5.3
6.5
u/l
0.64
25
67
148
793
1.95
12.25
5.1
2.8
25.8
25.3
mmol/l
0.81
143
761
23
43
5.41
11.83
1.3
1.4
68.6
60.3
%
0.44
17
36
582
4464
1.46
11.73
5.2
4.3
—
—
—
0
0
28
63
4.50
11.68
2.7
4.2
—
—
—
0
0
21
37
5.73
11.49
1.0
1.1
1654.8
1729.0
miu/ml
0.09
21
37
465
3452
1.48
10.93
1.9
1.7
44262730.7
38789172.7
pmol/l
0.04
366
2774
119
624
1.98
10.49
3.4
2.8
4.1
4.5
pmol/l
3.48
109
526
19
34
5.64
10.23
2.4
2.3
833.1
445.7
e6/l
0.60
14
24
30
79
3.85
10.23
1.2
1.2
—
—
—
0
0
169
1000
1.77
10.21
6.2
6.2
25.3
24.6
mmol/l
1.26
157
934
158
917
1.80
10.19
1.2
1.2
—
—
—
0
0
65
272
2.45
10.03
1.5
1.6
—
—
—
0
0
325
2286
1.52
9.81
33.3
30.3
1.3
1.5
inr
1.55
45
318
17
29
5.91
9.60
2.5
2.0
4138.8
85864.4
e6/l
0.49
11
13
39
128
3.10
9.54
3.1
3.8
—
—
—
0
0
703
5732
1.39
9.54
5.1
4.0
2.5
2.8
ug/l
0.21
606
5095
41
139
3.00
9.49
1.2
1.2
3.2
7.8
u/ml
1.18
18
66
48
179
2.73
9.36
1.6
1.2
—
—
—
0
0
12
14
8.63
9.35
1.8
1.2
—
—
—
0
0
17
30
5.71
9.28
1.5
1.0
—
—
—
0
0
17
30
5.71
9.28
1.2
1.1
—
—
—
0
0
59
248
2.43
9.04
1.6
1.2
—
—
—
0
0
13
18
7.27
8.85
1.3
1.2
—
—
—
0
0
472
3647
1.41
8.61
6.8
4.1
0.0
0.0
estimate
0.69
210
1106
34
111
3.11
8.42
1.6
1.3
—
—
—
0
0
21
49
4.33
8.41
1.4
2.5
63.8
60.3
mg/l
0.10
13
33
35
117
3.03
8.33
1.7
1.2
—
—
—
0
0
15
26
5.81
8.33
1.0
1.0
—
—
—
0
0
68
316
2.20
8.30
4.0
2.8
—
—
—
0
0
26
72
3.65
8.30
1.2
1.1
—
—
—
0
0
122
699
1.80
8.23
2.2
2.2
11.4
14.6
nmol/l
3.35
99
600
16
31
5.20
7.93
2.3
1.6
—
—
—
0
0
14
24
5.87
7.86
4.3
4.1
—
—
—
0
0
31
100
3.14
7.85
1.4
1.5
—
—
—
0
0
15
28
5.40
7.73
2.3
2.6
—
—
—
0
0
1385
12819
1.45
7.71
7.4
6.7
40.8
41.0
mmol/mol
0.34
1274
11698
76
380
2.05
7.71
1.8
1.6
18076.1
15602.9
e6/l
0.16
52
286
28
87
3.26
7.53
1.1
1.1
—
—
—
0
0
23
63
3.69
7.47
1.0
1.3
126.1
146.4
nmol/l
1.22
23
63
24
69
3.51
7.27
1.8
1.5
1.7
4105.0
u/l
—
6
22
117
691
1.74
7.14
5.4
3.6
—
—
—
0
0
55
250
2.24
7.12
1.4
1.5
—
—
—
0
0
29
97
3.02
6.94
2.0
1.9
507.2
494.3
min
0.22
18
74
11
8
13.83
6.89
6.0
1.3
—
—
—
0
0
46
198
2.36
6.76
1.4
1.5
68.6
69.4
%
0.05
27
127
87
483
1.84
6.54
5.8
5.5
1.3
1.3
mmol/l
0.06
78
430
13
25
5.23
6.49
1.1
1.1
—
—
—
0
0
26
85
3.09
6.48
1.5
1.2
0.4
2.3
u/ml
0.88
19
47
36
141
2.59
6.47
1.4
1.4
29.4
26.6
%
0.23
21
90
15
33
4.58
6.46
1.0
1.0
—
—
—
0
0
30
107
2.84
6.43
1.3
1.2
—
—
—
0
0
72
379
1.94
6.37
1.2
1.2
—
—
—
0
0
99
582
1.74
6.17
6.0
3.9
24.6
24.7
mmol/l
0.19
90
526
110
671
1.68
6.01
5.7
4.2
1.6
1.7
%
0.08
105
638
403
3192
1.34
6.00
3.1
2.8
0.8
0.8
ug/l
0.58
293
2245
13
27
4.84
5.97
3.0
2.5
—
—
—
0
0
40
172
2.36
5.93
1.4
1.4
92.9
58.5
mu/l
0.29
33
154
39
167
2.37
5.84
1.1
1.2
238.8
194.7
miu/ml
—
8
60
108
661
1.68
5.83
5.7
4.3
0.9
0.9
%
0.35
103
626
11
20
5.53
5.81
1.1
1.2
—
—
—
0
0
14
32
4.40
5.77
1.2
1.2
2.1
31.2
ug/l
—
7
14
34
138
2.49
5.71
1.2
1.2
—
—
—
0
0
40
177
2.29
5.58
1.2
1.3
0.7
0.7
nmol/l
0.12
35
168
16
42
3.84
5.54
1.2
1.1
—
—
—
0
0
16
42
3.84
5.54
1.2
1.1
—
—
—
0
0
16
42
3.84
5.54
1.2
1.1
—
—
—
0
0
8
5
16.07
5.41
2.6
4.4
—
—
—
0
0
100
614
1.67
5.36
6.3
4.3
—
—
—
0
0
10
18
5.58
5.32
2.1
2.5
—
—
—
0
0
10
18
5.58
5.32
1.7
1.7
—
—
—
0
0
10
18
5.58
5.32
14.1
11.5
5.0
5.9
mmol/l
—
10
18
20
63
3.20
5.32
1.2
1.1
—
—
—
0
0
13
30
4.36
5.30
1.3
1.4
—
—
—
0
0
13
30
4.36
5.30
1.0
1.3
0.7
0.7
umol/24h
—
6
13
1412
13320
1.37
5.29
5.6
5.1
6.0
6.1
mmol/l
0.73
1274
11894
35
151
2.35
5.19
1.2
1.3
—
—
nmol/l
—
0
0
211
1538
1.43
5.17
2.5
2.5
5.6
7.6
ug/l
1.17
186
1328
22
75
2.96
5.15
2.1
1.8
—
12.7
—
0
5
10
19
5.29
5.04
1.1
1.1
—
—
—
0
0
9
9
10.05
5.02
1.2
1.0
—
—
—
0
0
36
162
2.25
4.86
1.2
1.2
—
—
—
0
0
36
162
2.25
4.86
1.3
1.4
241.4
275.1
pmol/l
0.34
26
119
90
554
1.66
4.80
4.0
3.6
1.7
1.4
mmol/l
0.55
85
542
11
24
4.61
4.78
1.3
1.5
—
—
—
0
0
15
42
3.59
4.77
3.8
2.7
—
—
—
0
0
9
11
8.22
4.56
1.1
1.7
—
—
—
0
0
16
49
3.29
4.47
1.4
1.3
—
—
—
0
0
12
30
4.02
4.44
1.8
1.5
—
—
—
0
0
8
9
8.92
4.28
1.5
1.0
—
—
—
0
0
8
9
8.92
4.28
1.5
1.0
—
—
—
0
0
8
9
8.92
4.28
1.5
1.0
—
—
—
0
0
32
148
2.18
4.10
1.1
1.0
1.5
1.6
g/l
0.28
25
125
40
202
2.00
4.09
2.3
1.5
—
—
—
0
0
31
143
2.19
4.00
2.0
2.3
615.5
621.1
ml
0.03
19
94
23
93
2.49
3.97
1.0
1.0
316.8
292.6
mg/l
0.58
17
79
12
33
3.66
3.92
1.3
1.1
—
—
—
0
0
20
76
2.65
3.90
1.4
1.3
1.8
1.6
%
—
5
13
39
200
1.97
3.84
3.8
5.7
6.9
7.6
mmol/l
0.86
32
163
1333
12619
1.27
3.82
4.6
4.3
1.3
1.3
mmol/l
0.16
1200
11279
24
101
2.40
3.82
2.5
2.3
—
—
—
0
0
142
1021
1.43
3.79
1.4
1.4
—
—
—
0
0
18
66
2.75
3.76
1.0
1.1
—
—
—
0
0
39
203
1.94
3.69
3.6
2.2
—
—
—
0
0
69
430
1.63
3.59
2.9
2.2
175.2
71.1
ug/min
0.94
42
256
143
1042
1.41
3.55
1.6
1.5
—
—
—
0
0
8
13
6.18
3.50
1.1
1.1
—
—
—
0
0
6
6
10.03
3.50
1.0
1.2
—
—
—
0
0
17
63
2.72
3.49
1.0
1.0
—
—
—
0
0
11
31
3.57
3.48
3.5
1.4
—
—
—
0
0
1369
13044
1.26
3.45
5.0
4.9
1.4
1.4
mmol/l
4.97
1233
11785
1414
13526
1.28
3.44
5.6
5.5
2.4
2.6
mmol/l
9.72
1283
12251
121
861
1.44
3.43
1.2
1.2
—
—
—
0
0
27
126
2.16
3.42
1.7
1.4
270.4
273.9
mosm/kgh2o
0.29
19
91
168
1266
1.36
3.42
5.2
3.3
—
—
—
0
0
30
148
2.05
3.31
1.5
1.3
—
—
—
0
0
1379
13171
1.26
3.27
5.1
4.9
4.3
4.5
mmol/l
9.39
1255
11983
88
610
1.47
2.90
2.8
2.0
—
—
—
0
0
12
41
2.94
2.86
1.5
1.0
—
—
—
0
0
18
77
2.35
2.82
3.1
1.5
3.3
2.7
u/field
0.10
12
58
20
90
2.24
2.80
1.4
1.1
—
—
—
0
0
5
6
8.35
2.75
1.2
1.2
220.2
259.5
nmol/l
—
5
6
17
72
2.37
2.73
1.7
1.7
—
—
—
0
0
130
978
1.36
2.71
3.4
3.2
—
—
—
0
0
6
10
6.02
2.70
1.5
1.7
—
—
—
0
0
20
92
2.19
2.67
1.4
1.1
—
—
—
0
0
47
295
1.61
2.46
1.0
1.1
—
—
—
0
0
22
109
2.03
2.46
2.7
1.7
8.7
10.8
%
1.34
22
109
26
137
1.91
2.46
2.6
2.1
2.1
2.1
u/field
0.01
11
51
10
34
2.95
2.41
1.8
1.9
—
—
—
0
0
6
12
5.01
2.40
1.0
1.0
—
—
—
0
0
12
46
2.62
2.36
1.1
1.2
—
—
—
0
0
1124
10651
1.17
2.31
48.3
19.2
329.3
331.9
g/l
16.62
1118
10549
21
105
2.01
2.31
1.0
1.2
28.3
35.0
mmol/l
0.77
15
91
13
53
2.46
2.28
1.2
1.2
1.1
1.1
ratio
—
7
17
6
13
4.63
2.27
1.0
1.0
—
—
—
0
0
5
9
5.57
2.21
1.2
1.0
—
—
—
0
0
7
19
3.69
2.15
1.0
1.1
—
—
—
0
0
13
55
2.37
2.12
1.5
1.9
74.1
108.7
umol/l
—
7
37
5
10
5.01
2.07
1.2
1.0
—
—
—
0
0
5
10
5.01
2.07
1.6
1.1
—
—
—
0
0
20
103
1.95
2.05
2.2
1.9
—
—
—
0
0
58
401
1.46
2.02
3.9
3.2
0.8
0.8
nmol/l
0.10
42
302
18
90
2.01
2.00
1.6
2.5
—
—
—
0
0
105
806
1.32
1.98
5.4
3.5
—
—
—
0
0
60
420
1.44
1.97
6.4
4.2
—
—
—
0
0
12
51
2.36
1.95
1.3
2.2
1.5
9.3
nmol/l
1.04
12
41
9
33
2.74
1.93
1.2
1.3
—
—
—
0
0
33
206
1.61
1.83
1.3
1.2
—
—
—
0
0
28
450
0.62
1.80
1.6
1.5
—
—
—
0
0
27
161
1.69
1.78
1.1
1.3
10.3
8.8
u/l
0.22
20
131
9
36
2.51
1.74
5.2
1.3
—
—
—
0
0
10
42
2.39
1.67
3.3
1.5
—
—
—
0
0
5
14
3.58
1.61
1.0
1.2
2.0
1.7
umol/24h
—
5
14
5
15
3.34
1.52
1.4
1.7
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
11
51
2.16
1.50
1.0
1.3
0.3
0.2
nmol/l
—
6
43
19
319
0.59
1.49
1.6
1.7
—
—
—
0
0
37
251
1.48
1.48
1.7
1.7
5.5
4.1
iu/l
0.18
12
80
83
647
1.30
1.47
1.2
1.2
24.3
126.6
iu/ml
10.82
21
255
5
16
3.13
1.44
1.6
1.3
0.3
9.6
mmol/l
—
5
7
9
40
2.26
1.40
3.7
3.6
48.5
25.4
mu/l
—
9
35
5
17
2.95
1.36
1.6
1.4
41.8
43.9
umol/l
—
5
17
6
24
2.51
1.30
1.0
1.1
—
—
—
0
0
23
145
1.59
1.29
1.9
1.2
384132.6
158363.1
e6/l
0.32
17
103
19
115
1.66
1.25
1.0
1.0
257.1
326.2
ng/l
0.97
13
70
19
116
1.65
1.21
1.0
1.0
764.4
630.2
ng/l
0.83
14
67
8
37
2.17
1.21
1.1
1.3
—
—
—
0
0
11
57
1.94
1.17
1.1
1.1
6.7
14.8
iu/ml
—
6
9
5
20
2.50
1.15
1.0
1.3
—
—
—
0
0
45
338
1.34
1.09
3.4
2.3
—
—
—
0
0
16
97
1.66
1.06
2.1
1.7
—
—
—
0
0
13
75
1.74
1.03
1.9
1.5
0.9
0.9
g/l
0.02
13
75
340
3115
1.11
1.02
5.9
4.2
1.0
1.0
kg/l
0.07
53
487
62
493
1.27
1.01
1.4
1.2
—
—
—
0
0
49
379
1.30
0.99
1.2
1.1
—
—
—
0
0
20
132
1.52
0.97
1.2
1.3
—
—
—
0
0
401
3717
1.10
0.97
1.8
1.6
1.3
1.3
mmol/l
0.02
334
3061
17
108
1.58
0.96
11.4
10.9
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
1.1
0.7
u/ml
—
6
24
46
356
1.30
0.93
1.1
1.1
—
—
—
0
0
10
56
1.79
0.88
1.0
1.2
36.4
39.3
g/l
—
5
31
6
31
1.94
0.84
1.0
1.1
—
—
—
0
0
38
292
1.31
0.83
2.4
1.5
1.0
0.8
nmol/l
0.89
29
236
27
197
1.38
0.82
1.1
1.1
1.1
61.2
iu/ml
—
9
36
6
32
1.88
0.82
1.0
1.1
—
—
—
0
0
22
155
1.42
0.81
1.9
2.1
—
—
—
0
0
14
90
1.56
0.78
1.1
1.1
—
—
—
0
0
10
59
1.70
0.76
1.2
1.4
—
—
—
0
0
7
39
1.80
0.72
7.7
8.6
—
—
—
0
0
5
26
1.93
0.70
1.4
1.1
—
—
—
0
0
11
69
1.60
0.68
3.1
1.7
—
—
—
0
0
14
94
1.49
0.66
1.0
1.3
—
—
—
0
0
14
95
1.48
0.64
4.1
3.1
—
—
—
0
0
11
71
1.55
0.62
1.1
1.1
0.2
0.3
u/ml
—
6
17
8
50
1.60
0.61
5.9
2.1
—
—
—
0
0
15
108
1.39
0.53
1.7
3.3
7.0
7.1
mmol/l
—
9
67
6
39
1.54
0.53
1.3
1.5
—
—
—
0
0
13
91
1.43
0.53
2.1
1.8
—
71.4
—
0
7
19
143
1.33
0.52
1.2
1.7
—
—
—
0
0
9
65
1.39
0.50
1.0
1.0
—
—
—
0
0
43
506
0.85
0.48
14.7
11.0
—
—
—
0
0
11
77
1.43
0.45
1.2
1.7
—
—
—
0
0
15
113
1.33
0.42
1.1
1.5
—
—
—
0
0
27
221
1.23
0.42
2.0
1.7
—
—
—
0
0
47
541
0.87
0.41
1.2
1.4
—
—
—
0
0
15
116
1.30
0.37
1.1
1.4
—
—
—
0
0
15
117
1.28
0.35
1.1
1.4
—
—
—
0
0
15
118
1.27
0.33
1.1
1.4
—
—
—
0
0
39
341
1.15
0.32
4.4
3.7
28.5
30.4
mg/l
0.14
25
215
13
101
1.29
0.31
1.2
1.1
0.3
1.1
u/ml
—
7
35
7
53
1.32
0.31
1.3
1.3
—
—
—
0
0
13
102
1.28
0.30
1.9
1.3
0.6
1.3
promille
—
8
80
8
106
0.75
0.29
2.4
1.8
—
—
—
0
0
7
57
1.23
0.29
3.9
1.3
—
—
—
0
0
8
65
1.23
0.27
1.3
1.2
1259.4
446.2
u/l
—
8
59
31
273
1.14
0.25
1.9
1.8
45.3
44.8
nmol/l
0.04
31
255
400
3894
1.04
0.24
3.4
3.4
—
—
—
0
0
5
40
1.25
0.22
9.4
11.1
0.7
0.6
mmol/l
—
5
40
16
135
1.19
0.21
1.7
1.2
1.7
1.5
nmol/l
0.56
16
117
134
1291
1.04
0.15
1.7
1.6
—
—
—
0
0
10
83
1.21
0.15
1.7
3.9
—
—
—
0
0
13
116
1.12
0.09
1.2
1.4
—
—
—
0
0
8
76
1.05
0.07
1.7
4.0
—
—
—
0
0
20
187
1.07
0.06
2.6
2.7
—
—
—
0
0
21
198
1.06
0.05
2.2
1.9
207.8
199.3
pmol/l
0.11
21
186
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
0.00
1.0
1.0
—
2.5
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
5
58
0.86
0.00
2.0
2.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_MGUS_EXALLC – Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).