Oral leukoplakia and related diseases

K11_ORAL_LEUCOPLAC_RELAT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K13.2
  • Cause of death: ICD-10 K13.2

2 out of 7 registries used, show all original rules.

2037

4. Check minimum number of events

None

2037

5. Include endpoints

None

2037

6. Filter based on genotype QC (FinnGen only)

2037

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11356 6396 4921
Only index persons 10736 6104 4632
Unadjusted period prevalence (%)
Whole population 0.16 0.18 0.14
Only index persons 0.20 0.22 0.18
Median age at first event (years)
Whole population 59.45 60.72 57.82
Only index persons 59.14 60.32 57.57

-FinnGen-

Key figures

All Female Male
Number of individuals 2037 1161 876
Unadjusted period prevalence (%) 0.39 0.40 0.39
Median age at first event (years) 59.80 59.06 60.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1842
Matched controls
18420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K13.29
ICD-10 Finland
Indefinite leukoplakia
1249.4
323.0
1052
19
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
68.3
323.0
600
129
K13.20
ICD-10 Finland
Idiopathic leukoplakia
533.9
323.0
450
11
EKA10
NOMESCO Finland
Biopsy of cheek
37.6
313.7
405
137
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
289.7
272.7
272
11
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
15.3
203.3
352
280
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
11.8
194.0
382
401
K13.22
ICD-10 Finland
Erythroplakia of oral epithelium, including tongue
2075.7
186.6
178
*
K13.21
ICD-10 Finland
Leukoplakia caused by tobacco
855.7
162.2
157
*
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
16.0
148.6
250
179
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
131.0
136.3
145
12
SAA03
NOMESCO Finland
Extended examination of mouth
3.4
129.9
978
4611
L43.8
ICD-10 Finland
Other lichen planus
18.8
129.7
204
121
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
96.1
129.2
142
16
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.9
121.0
296
434
A07AA02
ATC
nystatin; oral
6.5
120.5
343
625
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.3
120.3
903
4169
ECA20
NOMESCO Finland
Biopsy of gingiva
27.0
116.7
163
66
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
18.6
111.7
176
104
SXA10
NOMESCO Finland
Epithel biopsy of mouth
23.1
111.4
163
77
SBA00
NOMESCO Finland
Microbiological examinations
12.5
106.7
199
177
K13.78
ICD-10 Finland
Other change in the oral mucosa
12.2
90.6
170
152
L43.9
ICD-10 Finland
Lichen planus, unspecified
13.5
87.8
157
126
K13.2
ICD-10 Finland
Leukoplakia and other disturbances of oral epithelium, including tongue
105.1
82.7
90
9
SXC03
NOMESCO Finland
Other oral or dental procedure
19.9
74.5
114
61
SAA04
NOMESCO Finland
Special inverstigation of mouth
5.5
73.7
234
473
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.7
73.4
667
3197
TEA00
NOMESCO Finland
Biopsy of lip
23.7
68.7
99
44
EHA10
NOMESCO Finland
Biopsy of palate
19.6
62.0
95
51
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
88.3
61.3
68
8
A01AB09
ATC
miconazole; local oral
3.6
59.2
298
935
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
9.6
48.1
101
111
B37.08
ICD-10 Finland
Other candidal stomatitis
16.1
46.5
76
49
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
26.5
46.1
64
25
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
60.6
45.5
53
9
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
153.6
43.0
45
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
21.7
42.9
63
30
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.8
41.8
189
535
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
16.6
41.0
66
41
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
40.2
910
6159
8070/3-C02.9
ICD-O-3
Squamous cell carcinoma, NOS, of tongue, NOS
406.1
40.2
40
*
EKB00
NOMESCO Finland
Excision of lesion of cheek
27.8
39.6
54
20
D20
ICPC
Mouth/tongue/lip symptom/complaint
4.5
38.7
145
345
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
38.2
1155
8622
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
38.0
797
5207
J02AC01
ATC
fluconazole; systemic
1.9
37.7
776
5033
EJB40
NOMESCO Finland
Hemiglossectomy
71.4
37.1
42
6
C04.0
ICD-10 Finland
Malignant neoplasm: Anterior floor of mouth
193.9
36.9
38
*
A01AC01
ATC
triamcinolone; local oral
6.4
36.8
100
164
L43.0
ICD-10 Finland
Hypertrophic lichen planus
17.8
36.4
57
33
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.7
36.3
285
1186
SBB10
NOMESCO Finland
Teeth copy
3.8
34.7
157
444
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.3
34.2
72
80
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
33.9
1256
9841
WX110
NOMESCO Finland
Local anesthesy
1.9
33.6
1256
9857
A01AB04
ATC
amphotericin B; local oral
3.5
33.2
163
493
C02.10
ICD-10 Finland
Malignant neoplasm of tip of tongue
332.8
33.0
33
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
9.2
33.0
70
79
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
4.9
32.7
110
234
EB1WA
NOMESCO Finland
NA
14.5
32.5
55
39
GBB00
NOMESCO Finland
Tracheostomy
8.6
32.3
71
85
D07AD01
ATC
clobetasol; topical
2.2
32.2
362
1807
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
73.5
31.9
36
5
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
9.6
31.5
65
70
D07AC01
ATC
betamethasone; topical
1.9
31.1
684
4451
R4110
NOMESCO Finland
Physiotherapy
1.9
29.8
551
3360
EDB00
NOMESCO Finland
Partial excision of mandible
37.7
29.4
37
10
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
3.1
28.7
165
561
K05.31
ICD-10 Finland
Periodontitis pronounced
2.5
27.1
236
1031
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
98.2
26.7
29
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
26.2
585
3776
K12.18
ICD-10 Finland
Other forms of stomatitis
12.3
26.1
47
39
K13.24
ICD-10 Finland
Gum problems in smokers
94.8
25.7
28
*
WX002
NOMESCO Finland
Sedation and analgesia
1.9
24.2
420
2473
B37.03
ICD-10 Finland
Chronic atrophic candida infection in the mouth
23.1
23.9
34
15
J01DB01
ATC
cefalexin; oral
1.8
23.7
1472
12680
8070/3-C04.9
ICD-O-3
Squamous cell carcinoma, NOS, of floor of mouth, NOS
126.6
23.6
25
*
EJ2S1
NOMESCO Finland
Photography of oral mucosa
28.6
23.2
31
11
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.3
22.3
119
383
K12.10
ICD-10 Finland
Stomatitis NOS
14.5
22.1
37
26
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
11.3
21.9
41
37
EAA10
NOMESCO Finland
Excision of lesion of lip
7.1
21.7
53
76
8070/3-C06.0
ICD-O-3
Squamous cell carcinoma, NOS, of cheeck mucosa
222.5
21.6
22
*
EJW99
NOMESCO Finland
Other operation on tongue or floor of mouth
116.4
21.6
23
*
ZXA05
NOMESCO Finland
Left side
1.7
21.6
522
3413
K14.61
ICD-10 Finland
Glossodynia
9.2
21.6
45
50
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
21.4
514
3351
EBA10
NOMESCO Finland
Surgical removal of tooth
2.4
20.9
195
879
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.7
20.8
643
4500
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
8.5
20.7
45
54
ZXC10
NOMESCO Finland
Use of laser
4.5
20.5
74
171
EMAK
NOMESCO Finland
NA
3.5
20.1
97
290
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
20.0
387
2350
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
19.8
312
1759
B37.02
ICD-10 Finland
Chronic hyperplastic candidal stomatitis
40.5
19.5
24
6
K13.6
ICD-10 Finland
Irritative hyperplasia of oral mucosa
7.5
19.5
46
63
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
19.5
212
1028
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
19.1
183
834
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
19.0
328
1910
K13.23
ICD-10 Finland
Leukokeratosis nicotina palati
+∞
18.8
18
*
K14.9
ICD-10 Finland
Disease of tongue, unspecified
21.1
18.6
27
13
C02.2
ICD-10 Finland
Malignant neoplasm: Ventral surface of tongue
101.1
18.6
20
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
18.6
325
1900
SDA02
NOMESCO Finland
Parodonthologic therapy
1.6
18.5
560
3867
N02AX02
ATC
tramadol; systemic, rectal
1.6
18.5
773
5803
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
10.8
17.9
34
32
R13
ICD-10 Finland
Dysphagia
2.5
17.5
145
614
K02.1
ICD-10 Finland
Caries of dentine
1.5
16.9
923
7320
L43.3
ICD-10 Finland
Subacute (active) lichen planus
19.5
16.9
25
13
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.0
16.7
96
327
K12.00
ICD-10 Finland
Recurrent oral aphthae
5.9
16.7
46
79
ECA30
NOMESCO Finland
Excision of lesion of gingiva
5.8
16.7
47
83
N05AH04
ATC
quetiapine; oral
1.9
16.6
271
1543
C04.1
ICD-10 Finland
Malignant neoplasm: Lateral floor of mouth
90.9
16.6
18
*
XQ802
NOMESCO Finland
Epicutan test
3.1
16.5
94
317
A02BC02
ATC
pantoprazole; systemic
1.5
16.3
1178
9909
D10.19
ICD-10 Finland
Benign tumor of the tongue UNS
12.9
16.2
28
22
SXC05
NOMESCO Finland
Other oral or dental procedure
2.7
16.0
110
419
K11.70
ICD-10 Finland
Hypoptyalism
9.6
15.9
32
34
N03AX16
ATC
pregabalin; oral
1.6
15.9
437
2922
Z01.2
ICD-10 Finland
Dental examination
1.5
15.9
678
5064
K05.30
ICD-10 Finland
Periodontitis complex
1.9
15.8
236
1301
EEB00
NOMESCO Finland
Partial excision of maxilla
60.5
15.8
18
*
J01FF01
ATC
clindamycin; systemic
1.6
15.6
482
3319
ZXA00
NOMESCO Finland
Right side
1.6
15.6
514
3602
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
15.6
936
7524
K13.03
ICD-10 Finland
Keilit UNS
19.4
15.6
23
12
EBB10
NOMESCO Finland
Insertion of dental implant
5.2
15.5
48
95
EJB99
NOMESCO Finland
Other excision on tongue and floor of mouth
38.4
15.4
19
5
EBA00
NOMESCO Finland
Extraction of tooth
1.6
15.4
550
3929
SPD05
NOMESCO Finland
Demanding fitting of total teeth prosthesis
12.5
14.9
26
21
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
5.3
14.9
45
87
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
14.7
381
2498
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
5.8
14.7
41
72
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
14.7
464
3208
N02AA05
ATC
oxycodone; systemic
1.8
14.6
278
1664
B37.01
ICD-10 Finland
Acute athrophy candidal stomatitis
15.5
14.4
23
15
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
14.3
343
2197
E0000UV
ATC
NA
1.5
14.3
660
4986
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.5
14.2
110
451
H02AB06
ATC
prednisolone; systemic
1.5
14.1
817
6468
B37.00
ICD-10 Finland
Acute pseudomembraneuous candidal stomatitis
14.5
14.1
23
16
L43
ICD-10 Finland
Lichen planus
5.8
13.9
39
69
XF612
NOMESCO Finland
Measurement of central venous pressure
17.7
13.8
21
12
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
13.8
483
3414
L43.1
ICD-10 Finland
Bullous lichen planus
24.0
13.8
19
8
EHB00
NOMESCO Finland
Excision of lesion of palate
20.2
13.8
20
10
130
Kela drug reimbursment
Malignant tumour
2.1
13.6
166
842
8070/3-C06.9
ICD-O-3
Squamous cell carcinoma, NOS, of mouth, NOS
+∞
13.6
13
*
SPF30
NOMESCO Finland
Soling for prothesis
3.9
13.4
55
145
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
13.4
619
4657
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.6
13.3
397
2695
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.2
13.2
144
698
UJF32
NOMESCO Finland
Coloscopy
1.5
13.2
473
3359
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
13.1
1139
9722
A02BC05
ATC
esomeprazole; systemic
1.5
13.0
722
5636
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.6
12.9
397
2710
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
12.8
860
6967
N02BE01
ATC
paracetamol; systemic, rectal
1.6
12.6
1539
14040
RD210
NOMESCO Finland
NA
4.7
12.6
42
91
RS316
NOMESCO Finland
NA
13.3
12.4
21
16
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
12.4
64
204
J01MA02
ATC
ciprofloxacin; systemic
1.5
12.3
678
5266
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.5
12.3
42
94
R03AC02
ATC
salbutamol; inhalant
1.4
12.1
867
7075
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
5.7
12.1
34
61
D07AB08
ATC
desonide; topical
1.9
12.0
184
1020
SPF20
NOMESCO Finland
Temporary soling for filling
5.8
11.9
33
58
EBB15
NOMESCO Finland
Insertion of dental implant abutment
5.8
11.9
33
58
N06AX21
ATC
duloxetine; oral
1.9
11.8
184
1025
K13.1
ICD-10 Finland
Cheek and lip biting
9.0
11.7
24
27
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
9.7
11.7
23
24
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
2.9
11.7
72
256
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
7.4
11.7
27
37
R06AE07
ATC
cetirizine; oral
1.4
11.7
700
5512
R01AD09
ATC
mometasone; nasal
1.4
11.5
716
5671
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
10.1
11.5
22
22
EJC99
NOMESCO Finland
Other reconstructive operations on tongue and floor of mouth
+∞
11.5
11
*
M25.5
ICD-10 Finland
Pain in joint
1.5
11.5
467
3397
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
11.5
87
354
C04.9
ICD-10 Finland
Malignant neoplasm: Floor of mouth, unspecified
120.7
11.4
12
*
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
3.1
11.4
61
200
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
11.4
398
2800
S01.50
ICD-10 Finland
Open wound in oral cavity
5.6
11.3
32
58
C02.9
ICD-10 Finland
Malignant neoplasm: Tongue, unspecified
35.2
11.3
14
*
H02AB07
ATC
prednisone; oral
1.7
11.2
259
1634
N07BA03
ATC
varenicline; oral
2.4
11.2
94
401
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
11.2
215
1286
D10.12
ICD-10 Finland
Bone tumor of the tip of the tongue
25.2
11.1
15
6
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
20.2
11.1
16
8
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
11.0
571
4360
WZA90
NOMESCO Finland
Other doctors statement
1.5
11.0
376
2629
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
10.9
776
6282
L43.2
ICD-10 Finland
Lichenoid drug reaction
43.6
10.9
13
*
SBA10
NOMESCO Finland
Measurement of excretion of saliva
5.1
10.9
33
65
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
6.9
10.9
26
38
J01CA04
ATC
amoxicillin; systemic
1.4
10.8
1358
12168
XQ800
NOMESCO Finland
Prick test
2.1
10.8
124
612
A02BA02
ATC
ranitidine; systemic
1.5
10.8
358
2481
N05BA01
ATC
diazepam; systemic, rectal
1.7
10.8
239
1489
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
10.7
254
1614
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.7
777
6310
C02.1
ICD-10 Finland
Malignant neoplasm: Border of tongue
60.3
10.6
12
*
S29
ICPC
Skin symptom/complaint other
1.6
10.6
292
1930
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
6.0
10.6
28
47
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
10.5
196
1158
N06AX11
ATC
mirtazapine; oral
1.4
10.5
526
3981
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.5
10.4
398
2847
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.5
10.3
401
2878
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
10.3
81
337
EJB60
NOMESCO Finland
Partial excision of floor of mouth
32.7
10.3
13
*
A02BC01
ATC
omeprazole; systemic
1.5
10.3
481
3585
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
10.3
173
988
EEA10
NOMESCO Finland
Biopsy of maxilla
23.5
10.2
14
6
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
10.2
369
2603
L04AD01
ATC
ciclosporin; systemic
3.9
10.2
40
103
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.6
10.1
73
290
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.6
10.1
73
291
J01FA06
ATC
roxithromycin; oral
1.4
10.1
692
5545
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
10.1
107
512
J01DA01
ATC
[U] cefalexin; systemic
1.4
10.1
1061
9147
D10.39
ICD-10 Finland
Benign tumor in other or unspecified part of oral cavity UNS
11.3
10.1
18
16
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
10.0
123
628
N05BA04
ATC
oxazepam; oral
1.5
10.0
416
3027
EJB20
NOMESCO Finland
Excision of lesion of base of tongue
40.3
10.0
12
*
WX872
NOMESCO Finland
Intensive care
2.2
9.9
99
461
K07.60
ICD-10 Finland
Snapping jaw
2.4
9.8
80
339
WX290
NOMESCO Finland
Other blockade of nerve
1.4
9.8
628
4965
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
8.2
9.8
21
26
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
8.2
9.8
21
26
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
2.7
9.8
66
251
N05CD07
ATC
temazepam; oral
1.7
9.8
233
1479
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.1
9.8
106
514
L04AA06
ATC
mycophenolic acid; systemic
3.9
9.8
39
102
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
9.8
176
1030
8070/3-C03.1
ICD-O-3
Squamous cell carcinoma, NOS, of lower gum
20.1
9.8
14
7
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
9.7
70
278
N05CF01
ATC
zopiclone; oral
1.4
9.7
562
4358
A01AB10
ATC
natamycin; local oral
2.7
9.7
63
236
ECB20
NOMESCO Finland
Oral alveoplasty
4.6
9.7
32
70
H02AB04
ATC
methylprednisolone; systemic
1.6
9.7
256
1673
L28
ICPC
Limited function/disability (L)
1.6
9.7
284
1909
SPA02
NOMESCO Finland
Preparation for dental prosthetics
3.2
9.7
49
156
K08.3
ICD-10 Finland
Retained dental root
2.0
9.6
122
634
P01BA02
ATC
hydroxychloroquine; oral
1.9
9.5
146
811
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
9.5
103
500
EAA30
NOMESCO Finland
Partial excision of lower lip
21.8
9.3
13
6
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
9.3
662
5320
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
9.3
601
4748
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
9.3
1527
14121
ECA35
NOMESCO Finland
Complicated excision of lesion of gingiva
10.7
9.3
17
16
E000006
ATC
NA
1.9
9.3
131
704
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
9.3
894
7550
A06AD11
ATC
lactulose; oral
1.6
9.2
251
1652
UJH02
NOMESCO Finland
Anoscopy
2.4
9.2
78
336
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
9.1
271
1826
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.1
806
6707
Z01.9
ICD-10 Finland
Special examination, unspecified
2.1
9.1
105
522
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.2
9.1
45
141
WX892
NOMESCO Finland
Monitored bed care
1.9
9.1
136
749
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
9.1
70
290
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
9.1
69
283
R51.80
ICD-10 Finland
Headache
1.6
9.0
221
1418
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.6
9.0
65
259
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
9.0
714
5836
127
Kela drug reimbursment
Transplant complication
4.0
8.9
34
86
L28.0
ICD-10 Finland
Lichen simplex chronicus
4.4
8.9
31
72
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
8.9
196
1222
R01AD08
ATC
fluticasone; nasal
1.4
8.9
444
3341
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.9
8.9
128
695
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.8
8.9
154
893
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.4
8.8
76
331
E000001
ATC
NA
1.5
8.8
323
2282
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
8.8
189
1169
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
8.8
309
2162
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.1
8.8
98
481
N03AX12
ATC
gabapentin; oral
1.6
8.7
266
1804
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
8.7
145
829
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
4.6
8.6
28
61
R07.0
ICD-10 Finland
Pain in throat
2.1
8.6
101
506
D07XC01
ATC
betamethasone, combinations; topical
1.6
8.6
201
1274
J37.0
ICD-10 Finland
Chronic laryngitis
2.5
8.5
63
255
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.0
8.5
105
538
M79.6
ICD-10 Finland
Pain in limb
1.4
8.5
594
4741
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
8.5
121
655
K13.09
ICD-10 Finland
Disease of the lips UNS
27.6
8.5
11
*
R4190
NOMESCO Finland
Nutritional therapy
2.6
8.4
58
225
8070/3-C03.0
ICD-O-3
Squamous cell carcinoma, NOS, of upper Gum
90.5
8.4
9
*
K11.2
ICD-10 Finland
Sialoadenitis
2.5
8.4
64
261
D19
ICPC
Teeth/gum symptom/complaint
1.4
8.4
390
2893
UJC01
NOMESCO Finland
Scopy of lower throat
4.5
8.4
28
63
EJC30
NOMESCO Finland
Reconstruction of tongue
+∞
8.3
8
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
8.3
301
2118
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
8.3
212
1373
J01FA10
ATC
azithromycin; systemic
1.3
8.3
899
7678
D83
ICPC
Mouth/tongue/lip disease
7.1
8.2
19
27
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.7
8.2
34
93
P01AB01
ATC
metronidazole; oral, rectal
1.4
8.2
640
5196
S21
ICPC
Skin texture symptom/complaint
1.6
8.2
203
1306
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
8.2
299
2111
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
8.1
455
3492
SPF10
NOMESCO Finland
Demanding repatation of teeth prosthesis
2.8
8.1
49
177
ZX090
NOMESCO Finland
Other technic of radiotherapy
2.5
8.1
59
236
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.1
118
646
K12.2
ICD-10 Finland
Cellulitis and abscess of mouth
4.5
8.1
27
61
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
8.0
110
589
EKA00
NOMESCO Finland
Incision of cheek
22.1
8.0
11
5
K14.09
ICD-10 Finland
Glossit UNS
22.1
8.0
11
5
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.0
8.0
43
145
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
7.9
408
3077
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
7.9
161
979
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
7.9
174
1082
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.9
706
5841
A01
ICPC
Pain general/multiple sites
1.8
7.9
137
795
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.0
7.9
42
140
J01AA02
ATC
doxycycline; systemic
1.4
7.9
1347
12280
L17
ICPC
Foot/toe symptom/complaint
1.4
7.8
416
3159
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.8
627
5106
C05.0
ICD-10 Finland
Malignant neoplasm: Hard palate
45.2
7.7
9
*
J01MA14
ATC
moxifloxacin; systemic
1.7
7.7
147
877
J01DA06
ATC
[U] cefuroxime; systemic
1.6
7.7
231
1559
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
7.7
138
808
K03.66
ICD-10 Finland
Tooth plaque
1.9
7.7
105
562
D07AC13
ATC
mometasone; topical
1.4
7.6
463
3599
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
7.6
121
681
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
25.1
7.6
10
*
K10.26
ICD-10 Finland
Periostitis of jaw (acute)(chronic)(suppurative)
25.1
7.6
10
*
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
4.0
7.6
28
70
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.6
384
2889
K14.60
ICD-10 Finland
Glossopyrosis
6.2
7.5
19
31
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
6.2
7.5
19
31
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
5.4
7.5
21
39
KMAK
NOMESCO Finland
NA
1.3
7.5
782
6606
R68.2
ICD-10 Finland
Dry mouth, unspecified
4.7
7.5
24
52
N06AB04
ATC
citalopram; systemic
1.4
7.5
356
2647
L04AX01
ATC
azathioprine; systemic
2.2
7.4
72
333
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
7.4
264
1851
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.4
374
2810
ZXA10
NOMESCO Finland
Bilateral
1.4
7.4
320
2334
B01AB05
ATC
enoxaparin; parenteral
1.4
7.4
519
4129
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.7
7.3
152
930
G44.2
ICD-10 Finland
Tension-type headache
1.6
7.3
193
1262
ZX120
NOMESCO Finland
Intravenous
1.7
7.3
155
955
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
7.3
104
565
C06.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of other and unspecified parts of mouth
+∞
7.3
7
*
EDB20
NOMESCO Finland
Hemimandibulectomy
+∞
7.3
7
*
C00.4
ICD-10 Finland
Malignant neoplasm: Lower lip, inner aspect
+∞
7.3
7
*
C06.21
ICD-10 Finland
Malignant tumor of the lower retromolar surface
+∞
7.3
7
*
C09.1
ICD-10 Finland
Malignant neoplasm: Tonsillar pillar (anterior)(posterior)
+∞
7.3
7
*
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
9.4
7.3
14
15
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
9.4
7.3
14
15
R01AD11
ATC
triamcinolone; nasal
1.7
7.2
143
865
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.4
7.2
33
99
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.2
7.2
69
320
Z72.0
ICD-10 Finland
Tobacco use
2.8
7.2
44
161
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
7.2
164
1031
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.2
281
2007
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.2
314
2292
C07AB07
ATC
bisoprolol; oral
1.3
7.2
813
6935
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
7.2
105
576
Z71.8
ICD-10 Finland
Other specified counselling
1.4
7.2
352
2628
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.7
7.2
29
79
SCD01
NOMESCO Finland
Simple removal of tooth plaque or tartar
5.0
7.1
21
42
ECB00
NOMESCO Finland
Suture of gingiva
2.3
7.1
60
263
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
7.1
100
540
N06AX16
ATC
venlafaxine; oral
1.6
7.1
196
1298
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
8.8
7.0
14
16
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
7.0
50
200
GD6AD
NOMESCO Finland
CT of chest and neck
10.1
7.0
13
13
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.4
7.0
57
245
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
7.0
107
595
A04
ICPC
Weakness/tiredness general
1.6
7.0
201
1343
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.0
163
1033
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.8
6.9
41
147
K06.23
ICD-10 Finland
Irritative hyperplasia of edentulous ridge [denture hyperplasia]
6.3
6.9
17
27
D07CC01
ATC
betamethasone and antibiotics; topical
1.5
6.9
206
1387
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
13.8
6.9
11
8
L50.8
ICD-10 Finland
Other urticaria
3.3
6.9
32
98
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
6.9
131
785
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.7
6.8
126
747
R03BB04
ATC
tiotropium bromide; inhalant
1.6
6.8
168
1079
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
6.8
202
1356
Z43.1
ICD-10 Finland
Attention to gastrostomy
11.0
6.8
12
11
K01.0
ICD-10 Finland
Embedded teeth
3.9
6.8
26
68
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
6.8
226
1562
TJD20
NOMESCO Finland
Change of gastrostomy tube
7.2
6.7
15
21
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
6.7
146
908
J05AB11
ATC
valaciclovir; oral
1.5
6.7
202
1363
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
6.7
83
430
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
6.7
311
2300
C08CA01
ATC
amlodipine; oral
1.3
6.7
608
5017
ZX114
NOMESCO Finland
Intramuscular
3.3
6.7
31
95
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.8
6.7
110
630
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.7
193
1290
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
6.6
111
637
K13.00
ICD-10 Finland
Cheilitis NOS
5.9
6.6
17
29
L12
ICPC
Hand/finger symptom/complaint
1.5
6.6
211
1445
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
6.6
369
2820
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.5
283
2061
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
6.5
342
2583
H03AA01
ATC
levothyroxine sodium; systemic
1.4
6.5
383
2953
SCC01
NOMESCO Finland
Simple fluorination of mouth or other corresponding procedure
2.5
6.5
46
184
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
3.8
6.5
25
66
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.5
360
2745
K13.3
ICD-10 Finland
Hairy leukoplakia
70.1
6.4
7
*
K13.70
ICD-10 Finland
Melanin pigmentation in the mouth
70.1
6.4
7
*
EJB50
NOMESCO Finland
Total glossectomy
70.1
6.4
7
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
6.4
174
1143
L03
ICPC
Low back symptom/complaint
1.4
6.4
364
2786
B37.0
ICD-10 Finland
Candidal stomatitis
3.5
6.4
27
77
D07BC01
ATC
betamethasone and antiseptics; topical
1.5
6.4
193
1305
K03.64
ICD-10 Finland
Dental calculus supragingival
1.4
6.3
394
3059
A46
ICD-10 Finland
Erysipelas
1.5
6.3
229
1608
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.6
6.3
167
1092
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
6.0
6.3
16
27
K10.20
ICD-10 Finland
Osteomyelitis (neonatal) of jaw (acute)(chronic)(suppurative)
11.1
6.3
11
10
J01MA12
ATC
levofloxacin; systemic
1.4
6.3
307
2286
C03CA01
ATC
furosemide; systemic
1.3
6.3
479
3843
R4120
NOMESCO Finland
Occupational therapy
1.8
6.3
101
573
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.5
6.3
45
182
D00.06
ICD-10 Finland
Cancer in situ in another part of the tongue
+∞
6.3
6
*
C03.9
ICD-10 Finland
Malignant neoplasm: Gum, unspecified
+∞
6.3
6
*
K13.02
ICD-10 Finland
Cheilitis angular
+∞
6.3
6
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
6.2
59
273
C02.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tongue
26.8
6.2
8
*
C02.0
ICD-10 Finland
Malignant neoplasm: Dorsal surface of tongue
26.8
6.2
8
*
C00.1
ICD-10 Finland
Malignant neoplasm: External lower lip
26.8
6.2
8
*
8070/3-C01.9
ICD-O-3
Squamous cell carcinoma, NOS, of base of tongue, NOS
26.8
6.2
8
*
D07AA02
ATC
hydrocortisone; topical
1.5
6.2
194
1320
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
4.1
6.2
22
54
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.2
141
888
SPA01
NOMESCO Finland
Pre-prosthetic dental procedures
6.3
6.2
15
24
SFA00
NOMESCO Finland
Small filling
1.5
6.1
197
1350
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
1.8
6.1
96
543
J01FA01
ATC
erythromycin; systemic
1.5
6.1
194
1329
F10.20
ICD-10 Finland
Alcohol dependence currently independent
2.7
6.1
37
137
ZZA00
NOMESCO Finland
Split skin graft
2.2
6.1
55
249
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.1
6.1
63
305
SDA10
NOMESCO Finland
Parodonthologic therapy of advnaced and complicated changes of alveolar bone
4.4
6.0
20
46
SPE01
NOMESCO Finland
Mucosa-supported partial denture
3.0
6.0
31
103
A02BC03
ATC
lansoprazole; oral
1.3
6.0
477
3847
WX199
NOMESCO Finland
Other local analgesia
2.3
6.0
50
219
N06AB03
ATC
fluoxetine; oral
1.5
6.0
190
1295

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
458
2018
2.64
65.77
1.8
1.4
—
—
—
0
0
1056
6915
2.09
57.31
2.8
2.1
—
—
—
0
0
56
66
8.70
43.95
4.7
2.2
—
—
—
0
0
345
1709
2.23
36.26
2.2
2.2
0.2
0.2
g/l
0.31
333
1593
1112
8264
1.76
33.55
7.4
6.1
1.2
1.2
mmol/l
1.34
1019
7472
1026
7495
1.74
32.49
2.2
2.0
96.0
94.8
pmol/l
0.32
536
3798
1616
13522
1.94
31.82
9.3
7.7
81.5
78.7
u/l
1.25
1527
12723
1123
8525
1.71
29.97
7.4
5.7
0.0
0.0
e9/l
0.52
961
7290
839
5909
1.71
29.38
7.1
5.7
—
—
—
0
0
1114
8493
1.69
28.76
7.5
5.7
0.6
0.6
e9/l
0.04
954
7249
1042
7824
1.68
28.35
5.1
4.8
35.2
35.2
g/l
0.00
982
7263
1143
8813
1.68
27.92
7.8
5.9
0.2
0.2
e9/l
0.35
996
7660
1127
8696
1.66
27.11
7.5
5.7
1.8
1.9
e9/l
1.42
984
7592
357
1983
1.97
27.06
2.0
1.8
—
—
—
0
0
1189
9310
1.67
26.93
7.0
6.3
11.9
11.6
umol/l
0.20
1134
8832
650
4355
1.72
26.71
8.9
6.6
—
—
—
0
0
1056
8041
1.65
26.52
7.4
5.8
58.2
57.5
%
1.15
981
7489
1067
8178
1.64
25.85
7.6
6.0
26.5
27.4
%
1.92
987
7587
1049
8007
1.64
25.83
7.9
6.2
8.8
8.8
%
0.03
977
7462
1520
12769
1.75
25.81
5.1
4.2
13.8
13.2
mm/h
0.81
1401
11777
1248
9962
1.65
25.60
10.7
9.0
4.2
4.1
e9/l
0.15
1078
8656
659
4475
1.70
25.54
5.1
3.9
88.9
89.2
%
0.11
648
4369
635
4298
1.69
24.76
2.5
2.4
—
—
—
0
0
1152
9060
1.62
24.66
8.1
6.9
1.2
1.2
mmol/l
3.29
1010
7632
1039
7977
1.62
24.48
7.5
5.9
2.9
2.9
%
0.14
964
7404
1016
7768
1.61
24.27
7.5
5.9
0.7
0.7
%
0.58
942
7224
830
6170
1.58
21.45
3.6
3.5
2.4
2.4
mmol/l
0.20
713
5369
460
2955
1.72
21.25
4.3
3.3
0.8
0.8
mmol/l
1.51
432
2747
131
534
2.55
21.06
3.7
3.5
—
—
—
0
0
395
2441
1.77
20.90
6.4
5.7
1.0
1.0
mmol/l
0.74
376
2252
760
5595
1.57
20.14
2.7
2.5
—
—
—
0
0
288
1641
1.88
19.81
6.4
7.5
8.4
10.3
mmol/l
5.00
272
1562
518
3527
1.63
18.84
4.9
3.9
588.4
388.5
ng/l
0.23
435
2859
607
4316
1.58
18.34
1.6
1.6
19.3
20.8
nmol/l
1.88
541
3642
1249
10376
1.53
18.31
6.1
4.9
6.8
6.8
mmol/l
0.02
1193
9759
1345
11354
1.54
18.30
5.6
4.7
774.3
2087.1
e6/l
0.76
12
181
681
4982
1.55
18.09
4.9
4.3
—
—
—
0
0
738
5526
1.53
17.48
2.4
2.2
182.7
213.9
u/l
0.69
702
5170
1720
15477
1.72
17.06
5.7
4.9
1.9
2.0
mu/l
0.80
1571
14050
225
1240
1.92
17.04
1.4
1.4
—
—
—
0
0
317
1953
1.74
16.66
3.2
2.6
9.9
8.3
umol/l
0.40
262
1708
723
5438
1.51
16.55
5.2
4.1
7.4
7.4
ph
0.86
85
1045
276
1647
1.78
16.18
3.0
2.3
42.1
41.0
u/l
0.04
220
1410
1269
10715
1.49
16.14
3.6
3.2
56.4
52.2
u/l
0.69
1164
9904
1832
16854
1.86
15.95
21.4
15.3
24.7
24.8
mg/l
0.03
1566
13461
445
3040
1.59
15.57
3.1
2.8
0.9
1.3
e6/l
1.23
259
1754
912
7255
1.47
15.48
2.6
2.3
76.4
78.6
nmol/l
1.55
817
6440
1369
11789
1.49
15.38
5.3
4.5
—
—
—
0
0
416
2822
1.60
14.93
3.3
3.0
2.6
2.5
e6/l
0.07
226
1548
441
3052
1.57
14.47
1.5
1.5
2.6
2.5
g/l
0.28
251
1808
921
7410
1.44
14.36
7.3
10.0
1.2
1.3
inr
1.75
172
2060
1466
12889
1.49
14.12
4.6
4.1
14.9
14.9
pmol/l
0.00
1330
11652
633
4758
1.48
14.01
3.9
3.1
—
—
—
0
0
379
2556
1.59
13.84
2.2
2.1
—
—
—
0
0
480
3433
1.52
13.45
1.3
1.2
1.4
1.5
u/ml
0.03
109
908
177
981
1.88
13.12
8.7
9.9
24.6
24.4
mmol/l
0.53
166
921
1885
17668
1.90
13.05
24.0
18.0
139.3
139.7
mmol/l
5.82
1847
17228
642
4897
1.45
12.97
3.9
3.2
0.4
0.5
e6/l
0.87
489
3707
985
8134
1.41
12.72
4.1
4.0
—
—
—
0
0
322
2139
1.60
12.43
8.0
7.7
5.2
5.1
kpa
0.88
311
2042
322
2139
1.60
12.43
8.0
7.7
12.2
12.2
kpa
0.03
312
2043
322
2140
1.60
12.41
8.0
7.7
1.3
1.1
mmol/l
0.31
258
1673
1885
17709
1.86
12.35
24.2
18.1
4.0
4.0
mmol/l
0.31
1845
17243
853
6903
1.41
12.22
3.0
2.8
132.8
143.6
ug/l
0.66
783
6321
38
105
3.67
12.06
2.3
2.1
961.6
705.1
e6/l
0.73
15
43
283
1835
1.63
12.05
2.2
2.2
140.1
150.2
ug/g
0.14
232
1456
539
4023
1.46
12.04
3.9
3.8
—
—
—
0
0
478
3490
1.48
11.93
1.7
1.8
1098.2
1189.6
nmol/l
1.19
368
2623
585
4448
1.44
11.81
2.3
2.2
2.9
3.1
mg/l
0.60
508
3764
55
196
2.86
11.58
3.5
3.5
—
—
—
0
0
414
5607
0.67
11.48
2.8
3.0
—
—
—
0
0
323
2186
1.57
11.46
1.5
1.3
518.3
534.7
titre
0.06
71
473
769
6174
1.39
11.29
4.5
3.8
53.7
115.8
e6/l
2.64
552
4422
172
993
1.80
11.18
1.4
1.4
—
—
—
0
0
240
1528
1.65
10.95
1.8
1.5
—
—
—
0
0
602
4663
1.41
10.78
3.0
2.7
4306.8
5819.0
umol/l
0.40
517
4013
674
5324
1.40
10.77
4.0
3.3
26.9
76.4
e6/l
3.12
519
4105
287
1919
1.58
10.69
8.5
8.0
95.7
95.5
%
0.22
281
1852
337
2337
1.53
10.67
8.4
6.9
103.9
104.3
mmol/l
0.85
329
2285
238
1526
1.63
10.55
9.3
8.5
—
—
—
0
0
362
2569
1.50
10.24
2.5
2.5
2.3
2.3
g/l
1.03
342
2380
86
403
2.18
10.18
1.3
1.2
—
—
—
0
0
267
1777
1.58
10.13
9.0
8.5
118.2
120.7
g/l
1.18
262
1715
242
1577
1.61
10.03
1.7
1.6
—
—
—
0
0
248
1630
1.59
9.92
8.0
7.1
1.3
1.4
mmol/l
0.06
240
1567
137
766
1.85
9.89
1.2
1.2
—
—
—
0
0
384
2785
1.47
9.70
2.4
2.5
11.8
12.8
umol/l
2.17
366
2585
83
392
2.16
9.65
3.0
2.8
35.7
35.6
umol/l
0.02
74
329
283
1936
1.54
9.48
1.3
1.3
—
—
—
0
0
1891
17962
1.74
9.43
14.1
11.0
25.9
25.9
u/l
0.01
1831
17311
91
450
2.07
9.40
2.8
3.2
1.5
1.6
mg/l
0.75
85
410
194
1221
1.65
9.24
1.1
1.2
—
—
—
0
0
342
2449
1.48
9.18
28.7
25.9
1.4
1.4
inr
0.06
36
327
254
1709
1.56
9.16
1.6
1.5
—
—
—
0
0
1838
17376
1.59
8.80
18.2
14.6
—
—
—
0
0
145
856
1.75
8.75
4.6
3.9
24.2
24.1
mmol/l
0.20
133
771
1712
15959
1.46
8.65
6.6
6.1
40.8
40.3
mmol/mol
0.69
1595
14674
99
521
1.95
8.62
1.5
1.4
273.6
280.5
ug/g
0.15
63
304
454
3468
1.40
8.52
3.3
3.0
2.5
2.5
mmol/l
1.09
382
3057
313
2234
1.47
8.51
1.4
1.3
—
—
—
0
0
373
2755
1.43
8.46
2.1
2.1
29.7
29.8
s
0.09
363
2661
334
2417
1.46
8.46
2.5
2.6
20.1
22.5
%
3.19
285
2064
485
3751
1.38
8.44
1.8
1.8
1.2
1.3
mg/l
0.16
386
2902
110
608
1.86
8.27
1.3
1.2
2.4
0.9
u/ml
0.41
15
54
455
3496
1.39
8.21
3.2
2.8
545.0
542.5
mosm/kgh2o
0.07
380
2964
679
5556
1.33
8.16
2.7
3.1
1537.2
1449.6
ng/l
0.12
581
4765
36
125
2.91
8.02
1.9
2.0
47.7
43.4
%
—
7
14
194
1266
1.59
7.98
2.9
2.7
11.0
10.6
g/l
0.55
177
1151
481
3758
1.37
7.78
3.0
2.6
4.5
5.4
e6/l
1.20
417
3288
93
505
1.88
7.42
1.3
1.1
—
—
—
0
0
672
5549
1.31
7.42
2.8
2.5
58.8
57.7
u/l
0.20
625
5111
1926
18524
1.73
7.34
30.8
22.6
248.4
248.3
e9/l
0.02
1885
18026
276
1980
1.46
7.27
1.8
1.6
—
—
—
0
0
260
1845
1.47
7.24
4.2
4.4
—
—
—
0
0
157
997
1.62
7.24
9.5
10.7
—
—
—
0
0
38
145
2.65
7.14
1.9
2.1
1.0
1.1
e9/l
0.19
21
88
1925
18528
1.71
7.09
30.7
22.5
91.9
91.4
fl
5.23
1903
18241
1925
18528
1.71
7.09
30.6
22.5
30.5
30.4
pg
2.19
1903
18239
151
955
1.63
7.08
2.5
2.5
—
—
—
0
0
1925
18530
1.71
7.06
30.8
22.6
4.4
4.5
e12/l
7.13
1878
17966
1925
18533
1.70
7.02
30.8
22.6
6.9
6.7
e9/l
0.79
1876
17974
1925
18535
1.70
6.99
30.9
22.7
132.7
134.5
g/l
5.69
1905
18247
211
1448
1.51
6.93
3.9
3.9
87.1
91.8
ng/l
0.37
182
1256
31
109
2.87
6.80
3.2
3.8
—
—
—
0
0
335
2522
1.39
6.72
1.3
1.2
—
—
—
0
0
1356
12359
1.29
6.66
4.4
4.0
—
—
—
0
0
373
2863
1.37
6.65
1.4
1.3
37.7
37.9
iu/ml
0.01
109
931
170
1124
1.56
6.62
2.7
3.2
4.4
4.1
e9/l
0.69
123
851
813
6961
1.28
6.62
3.8
3.9
31.1
60.8
ng/l
1.83
589
5043
230
1623
1.47
6.59
2.7
3.0
247.7
207.4
ng/l
0.57
210
1484
1757
16631
1.41
6.56
5.2
4.8
6.0
6.0
mmol/l
0.02
1606
15037
285
2095
1.42
6.56
2.5
2.5
1.9
1.8
%
0.35
252
1858
225
1589
1.47
6.42
1.5
1.4
—
—
—
0
0
118
722
1.67
6.31
1.9
1.5
5.6
22.3
u/ml
—
6
21
33
126
2.65
6.23
1.2
1.1
145.0
133.2
titre
—
6
22
134
853
1.61
6.15
1.6
1.8
1.4
1.6
g/l
1.12
119
744
44
194
2.30
6.14
1.3
1.3
281.7
276.0
mosm/kgh2o
0.69
38
147
153
1006
1.56
6.12
1.7
1.8
1.3
1.5
g/l
0.74
139
912
17
45
3.80
5.81
1.7
1.4
—
—
—
0
0
1596
14971
1.31
5.66
24.2
16.6
39.0
39.4
%
0.95
1132
10130
230
1672
1.42
5.62
2.1
2.5
11.7
6.9
ug/l
0.61
200
1481
33
133
2.51
5.62
1.6
1.8
—
—
—
0
0
165
1125
1.51
5.61
2.4
2.5
25.4
24.2
au/ml
—
6
49
109
677
1.64
5.54
1.9
2.5
10.2
10.2
g/l
0.06
92
581
21
67
3.16
5.47
1.2
1.2
—
—
—
0
0
179
1249
1.47
5.44
5.6
5.0
—
—
—
0
0
218
1587
1.42
5.29
2.7
2.2
373.0
369.1
nmol/l
0.09
192
1450
217
1581
1.42
5.24
2.0
2.6
74.0
70.1
e9/l
0.67
158
1212
1482
13816
1.27
5.23
29.4
20.1
331.2
332.0
g/l
2.36
1469
13711
29
115
2.54
5.13
1.2
1.1
—
—
—
0
0
32
134
2.41
5.06
2.4
2.1
—
—
—
0
0
79
463
1.73
5.01
2.4
1.5
0.2
0.2
g/l
1.11
74
439
94
578
1.66
5.00
1.6
2.4
38.0
37.4
g/l
0.44
85
501
646
5534
1.25
4.87
3.9
3.3
—
—
—
0
0
748
6519
1.23
4.79
3.6
3.6
—
5.7
—
0
5
658
5657
1.24
4.78
3.4
3.2
6.8
7.2
mmol/l
2.01
549
4726
1785
17119
1.35
4.61
5.7
5.2
2.6
2.7
mmol/l
4.12
1650
15621
72
423
1.73
4.55
1.5
1.2
15.1
3.5
u/ml
0.47
12
49
341
2729
1.30
4.48
1.3
1.2
13.0
12.0
u/ml
0.08
105
1029
847
7525
1.21
4.39
10.6
9.8
0.0
0.0
e9/l
0.29
673
6126
1685
16059
1.29
4.36
4.4
4.1
1.3
1.3
mmol/l
0.13
1528
14520
232
1769
1.35
4.27
4.5
3.6
—
7.4
—
0
10
48
258
1.88
4.09
1.1
1.1
—
—
—
0
0
66
393
1.70
4.02
4.0
2.8
—
—
—
0
0
631
5485
1.22
3.99
3.5
3.3
562.1
306.0
mg/l
0.55
416
3429
44
232
1.92
3.98
5.3
4.8
353.8
359.9
umol/l
0.11
37
199
26
113
2.32
3.85
2.0
2.1
15.4
13.4
%
0.34
14
45
45
243
1.87
3.80
2.6
2.5
—
—
—
0
0
26
115
2.28
3.71
2.0
2.1
74.5
72.6
%
0.32
26
106
39
205
1.92
3.59
1.5
1.2
—
—
—
0
0
931
8462
1.18
3.51
4.0
3.9
0.0
0.0
estimate
1.08
116
1496
655
5776
1.20
3.48
4.0
4.0
7.0
8.7
mg/mmol
0.76
410
3591
91
612
1.51
3.41
3.2
3.5
43.9
65.9
mg/l
1.00
78
502
46
260
1.79
3.40
2.0
1.9
—
—
—
0
0
91
613
1.51
3.38
3.2
3.5
36.7
80.8
mg/l
1.12
76
505
56
336
1.69
3.37
1.3
1.3
272.1
209.9
miu/ml
0.44
19
141
123
882
1.42
3.33
1.4
1.2
—
—
—
0
0
43
240
1.81
3.32
1.6
1.7
0.5
0.9
g/l
2.13
29
183
87
585
1.51
3.27
1.6
1.6
—
—
—
0
0
113
804
1.43
3.20
2.4
1.9
—
—
—
0
0
43
243
1.79
3.20
2.2
2.3
4032.0
1145.1
u/ml
0.31
43
234
132
966
1.39
3.19
1.3
1.3
272.1
204.7
u/ml
0.46
123
881
217
1712
1.30
3.18
4.4
3.5
1.6
2.0
mmol/l
0.67
194
1376
1737
16756
1.25
3.15
5.0
4.7
4.6
4.6
mmol/l
2.40
1600
15377
17
67
2.55
3.12
26.4
31.9
7.2
7.0
ug/l
0.11
12
58
47
275
1.73
3.11
1.4
1.4
—
—
—
0
0
916
8375
1.17
3.08
5.4
5.2
0.0
0.0
estimate
0.50
120
1542
169
1295
1.33
3.06
2.7
2.5
—
—
—
0
0
69
449
1.56
3.03
2.0
1.7
24392.0
14137.7
e6/l
0.68
52
320
23
106
2.18
3.03
5.0
2.9
31.3
39.2
%
—
9
36
197
1547
1.30
3.00
2.7
2.7
66.9
66.5
g/l
0.34
182
1404
47
279
1.70
2.97
2.0
1.8
—
—
—
0
0
608
5391
1.18
2.95
4.0
4.0
—
—
—
0
0
47
280
1.69
2.94
2.0
1.8
—
—
—
0
0
47
281
1.69
2.90
2.0
1.8
—
—
—
0
0
192
1510
1.30
2.90
3.7
3.5
—
—
—
0
0
14
52
2.70
2.89
2.1
2.3
31.6
29.4
%
0.16
14
45
38
214
1.79
2.89
1.2
1.2
—
—
—
0
0
34
185
1.85
2.88
3.7
2.5
—
—
—
0
0
1720
16613
1.23
2.84
5.0
4.6
1.5
1.5
mmol/l
0.23
1582
15135
379
4412
0.83
2.83
3.8
3.6
—
—
—
0
0
13
47
2.78
2.81
1.1
1.0
—
—
—
0
0
38
216
1.77
2.81
2.2
1.7
—
—
—
0
0
147
1119
1.34
2.80
1.2
1.3
—
—
—
0
0
20
411
0.48
2.80
3.8
3.1
7.5
7.5
mmol/l
0.02
20
400
907
8330
1.16
2.79
4.0
3.9
0.0
0.0
estimate
0.00
118
1530
16
66
2.44
2.71
3.9
1.5
168.0
91.0
umol/l
—
7
38
28
146
1.93
2.70
1.4
1.4
8.0
7.0
g/l
0.34
20
99
28
146
1.93
2.70
1.4
1.4
0.4
0.4
g/l
0.20
20
99
28
146
1.93
2.70
1.4
1.4
2.6
3.0
g/l
0.64
20
100
14
54
2.60
2.70
2.1
2.3
7.6
10.1
%
0.57
14
46
26
482
0.53
2.67
5.4
4.7
—
—
—
0
0
10
32
3.14
2.64
1.2
1.1
—
—
—
0
0
63
417
1.53
2.61
1.8
1.6
—
—
—
0
0
28
148
1.90
2.61
1.4
1.4
—
—
—
0
0
79
1116
0.70
2.59
1.4
1.4
—
—
—
0
0
11
38
2.91
2.58
2.3
1.4
—
—
—
0
0
45
276
1.64
2.56
1.5
1.7
—
—
—
0
0
23
435
0.52
2.54
3.4
3.0
1.5
1.5
mmol/l
0.26
23
422
13
50
2.61
2.53
2.2
2.4
123.2
128.5
nmol/l
0.10
13
44
97
704
1.40
2.52
2.6
2.6
—
—
—
0
0
26
136
1.92
2.50
1.3
1.4
46.8
33.6
u/l
0.80
21
109
423
3686
1.19
2.48
4.5
4.3
1.0
1.0
kg/l
0.05
50
539
9
26
3.47
2.48
2.6
2.3
18.2
18.7
umol/l
—
9
26
18
82
2.21
2.47
4.1
2.0
6.9
8.6
umol/l
0.24
13
46
150
1171
1.30
2.43
9.1
7.2
24.6
24.5
mmol/l
0.06
144
1095
35
204
1.73
2.41
1.4
1.6
—
—
—
0
0
100
1340
0.73
2.40
3.9
4.1
0.1
0.6
%
0.75
31
348
108
1428
0.74
2.38
4.1
4.2
—
—
—
0
0
21
104
2.03
2.36
1.8
1.6
—
—
—
0
0
532
4748
1.16
2.32
1.8
1.7
1.4
1.4
mmol/l
0.88
474
3951
236
1960
1.23
2.30
3.8
4.1
47.4
20.5
ug/l
0.41
202
1610
34
200
1.71
2.28
2.1
1.5
—
—
—
0
0
34
200
1.71
2.28
2.1
1.5
—
—
—
0
0
34
200
1.71
2.28
2.1
1.5
—
—
—
0
0
34
200
1.71
2.28
2.1
1.5
—
—
—
0
0
32
185
1.74
2.28
1.9
1.6
—
—
—
0
0
41
254
1.63
2.28
1.1
1.0
—
—
—
0
0
118
1530
0.76
2.28
4.2
3.8
1.2
1.2
mmol/l
0.01
106
1334
615
5557
1.15
2.26
4.9
5.0
3.9
2.8
ug/l
0.33
558
4973
1435
13731
1.15
2.25
26.3
18.8
13.9
13.8
%
3.69
1409
13404
108
1415
0.75
2.25
3.9
4.0
0.2
0.1
%
0.20
39
408
46
295
1.57
2.23
1.2
1.4
17.6
10.2
u/l
1.33
33
238
22
114
1.94
2.20
1.7
2.4
—
—
—
0
0
142
1118
1.29
2.18
2.5
2.2
12.4
12.7
nmol/l
0.16
118
990
35
212
1.66
2.13
1.4
1.3
—
—
—
0
0
62
429
1.46
2.13
2.9
2.2
—
—
—
0
0
104
1358
0.75
2.12
4.0
3.8
0.5
0.6
%
0.16
30
321
13
55
2.37
2.12
1.0
1.5
12.3
13.3
g/l
—
6
42
65
455
1.44
2.11
3.8
3.6
—
—
—
0
0
114
878
1.32
2.07
3.7
2.5
1.6
1.2
%
2.35
114
872
126
985
1.30
2.06
3.3
3.1
4.4
4.4
pmol/l
0.01
111
863
52
350
1.50
2.05
1.4
1.3
58.0
59.7
mmol/l
0.13
45
278
14
63
2.23
2.01
1.1
1.3
40.4
37.2
g/l
—
8
34
144
1151
1.27
1.99
3.3
3.1
—
—
—
0
0
35
217
1.62
1.97
1.1
1.4
287.8
288.5
pmol/l
0.00
24
167
33
202
1.64
1.96
1.2
1.2
—
—
nmol/l
—
0
0
6
16
3.76
1.93
1.2
1.0
—
—
—
0
0
56
390
1.45
1.89
1.8
1.8
3.4
4.5
iu/l
0.48
13
120
25
144
1.75
1.85
1.0
1.2
—
—
—
0
0
11
46
2.40
1.85
1.6
1.5
—
—
—
0
0
55
385
1.44
1.82
1.1
1.2
—
—
—
0
0
127
1012
1.27
1.82
1.3
1.2
148.3
138.1
iu/ml
0.12
45
382
365
3227
1.16
1.79
2.9
3.0
0.7
0.7
ug/l
0.97
245
2159
21
116
1.82
1.78
2.2
1.4
1.5
1.1
promille
0.59
16
90
31
192
1.62
1.78
1.5
1.3
8073.2
121642.4
e6/l
1.85
18
111
90
693
1.31
1.69
3.6
3.3
2026.9
5948.7
u/ml
0.43
80
593
90
693
1.31
1.69
1.7
1.5
—
—
—
0
0
18
97
1.86
1.66
1.7
1.7
—
—
—
0
0
11
49
2.25
1.63
1.2
1.6
—
—
—
0
0
5
14
3.58
1.61
1.0
1.0
—
—
—
0
0
40
271
1.49
1.59
1.6
1.4
104.3
124.2
u/ml
—
6
53
25
152
1.65
1.56
2.4
1.8
10.9
11.1
%
0.09
25
152
16
85
1.89
1.55
3.1
3.8
—
—
—
0
0
58
425
1.38
1.53
2.8
3.1
0.8
0.8
nmol/l
0.54
39
332
16
86
1.87
1.50
1.0
1.1
—
—
—
0
0
81
627
1.30
1.49
2.7
3.2
0.2
0.3
g/l
1.86
38
249
12
58
2.08
1.49
1.2
1.2
—
—
—
0
0
46
327
1.42
1.45
1.7
1.6
—
—
—
0
0
43
302
1.43
1.45
1.5
1.4
—
—
—
0
0
15
80
1.88
1.44
1.0
1.0
—
—
—
0
0
13
240
0.54
1.44
2.3
2.4
—
—
—
0
0
33
220
1.51
1.44
1.5
1.3
2835.4
1771.1
e6/l
0.32
22
151
12
59
2.04
1.43
1.6
2.0
—
—
—
0
0
6
22
2.73
1.43
1.5
1.4
40.3
45.0
umol/l
—
6
22
123
1490
0.81
1.43
3.9
4.0
0.5
0.9
%
1.97
45
443
21
126
1.67
1.40
1.1
1.3
—
—
—
0
0
12
61
1.97
1.32
1.8
1.9
—
—
—
0
0
5
18
2.78
1.28
1.2
1.1
—
—
—
0
0
60
457
1.32
1.28
1.6
2.1
10.4
12.0
mg/l
0.98
53
419
65
502
1.30
1.26
1.0
1.1
—
—
—
0
0
24
154
1.57
1.26
1.1
1.2
—
—
—
0
0
28
187
1.50
1.24
1.0
1.1
1.3
4.9
u/ml
2.49
15
88
45
330
1.37
1.23
1.5
1.6
373.4
275.2
mu/l
0.46
38
300
30
204
1.48
1.22
2.7
2.1
—
—
—
0
0
5
19
2.64
1.21
1.2
1.3
—
—
—
0
0
22
141
1.57
1.17
3.4
4.8
73.9
39.9
u/ml
—
7
43
14
79
1.78
1.17
3.4
4.0
—
—
—
0
0
17
102
1.67
1.16
1.1
1.0
—
—
—
0
0
5
20
2.50
1.15
1.2
1.6
—
—
—
0
0
12
65
1.85
1.13
1.6
2.0
—
—
—
0
0
10
51
1.97
1.11
1.7
1.9
—
—
—
0
0
26
177
1.47
1.08
1.3
1.2
—
—
—
0
0
18
113
1.60
1.05
2.7
1.7
—
—
—
0
0
26
179
1.46
1.03
1.6
1.4
—
—
—
0
0
12
68
1.77
1.00
1.5
2.2
632.7
27449.3
e6/l
—
6
42
7
35
2.00
1.00
2.9
1.4
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
9.5
6.7
mg/g
—
5
23
9
50
1.80
0.96
1.8
1.4
1.7
2.0
umol/l
—
9
44
9
51
1.77
0.94
1.3
1.1
331.4
278.3
pmol/l
—
9
36
9
52
1.73
0.92
1.2
1.1
—
—
—
0
0
34
252
1.36
0.92
1.1
1.1
—
—
—
0
0
90
755
1.20
0.91
2.3
2.0
0.6
1.7
ug/l
1.60
74
666
59
474
1.25
0.90
1.1
1.1
—
—
—
0
0
26
186
1.40
0.87
3.7
3.5
58.8
55.4
%
0.32
18
125
90
760
1.19
0.86
6.4
4.4
—
—
—
0
0
50
398
1.26
0.84
1.3
1.3
37.5
35.3
iu/l
0.20
41
336
28
206
1.36
0.81
4.0
4.0
—
—
—
0
0
31
232
1.34
0.81
1.3
1.2
2.2
6.2
u/ml
1.93
15
99
98
840
1.18
0.81
3.0
3.8
—
—
—
0
0
31
407
0.76
0.79
5.9
4.2
—
—
—
0
0
6
33
1.82
0.79
1.0
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
47.2
—
0
9
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
9
54
1.67
0.74
4.9
2.4
—
—
—
0
0
26
193
1.35
0.73
1.2
1.1
—
—
—
0
0
24
176
1.37
0.72
2.1
1.9
4243.4
1915.2
u/l
—
7
68
22
159
1.39
0.72
1.1
1.5
—
—
—
0
0
14
92
1.53
0.72
1.6
1.6
—
—
—
0
0
50
407
1.23
0.72
2.3
2.2
121.4
129.9
g/l
1.34
26
302
10
60
1.67
0.72
1.2
1.7
—
—
—
0
0
23
168
1.37
0.71
1.2
1.4
—
—
—
0
0
7
40
1.75
0.71
6.1
8.5
—
—
—
0
0
5
26
1.93
0.70
8.4
13.7
4.5
5.4
mmol/l
—
5
26
5
26
1.93
0.70
1.2
1.4
—
—
—
0
0
27
204
1.33
0.69
1.3
1.2
—
—
—
0
0
28
213
1.32
0.68
1.1
1.1
0.5
1.8
u/ml
—
8
85
5
27
1.85
0.68
1.0
1.0
—
—
—
0
0
24
179
1.34
0.67
1.6
1.4
18242.3
114092.7
e6/l
1.04
18
125
69
586
1.18
0.66
1.1
1.1
—
—
—
0
0
5
28
1.79
0.66
1.4
1.7
—
—
—
0
0
24
180
1.34
0.65
1.0
1.1
0.5
1.5
u/ml
0.79
11
71
5
30
1.67
0.61
7.6
8.4
—
—
—
0
0
21
156
1.35
0.61
2.0
2.0
—
1.1
—
0
5
8
51
1.57
0.60
1.6
2.0
1.8
1.1
ug/l
—
8
46
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
34
272
1.25
0.59
1.1
1.2
237.9
274.7
u/ml
0.32
21
155
40
327
1.23
0.58
1.7
1.5
—
—
—
0
0
22
166
1.33
0.58
3.8
3.1
11.0
30.5
mg/l
1.24
15
129
28
219
1.28
0.58
1.2
1.3
—
—
—
0
0
19
140
1.36
0.58
1.1
1.2
—
—
—
0
0
184
1690
1.10
0.57
1.8
1.6
—
—
—
0
0
38
310
1.23
0.57
1.3
1.2
53.6
38.2
u/l
0.30
32
268
5
86
0.58
0.56
3.0
2.8
—
—
—
0
0
68
782
0.87
0.54
1.4
1.5
—
—
—
0
0
37
304
1.22
0.53
1.9
1.5
—
—
—
0
0
13
91
1.43
0.53
1.1
1.3
139.3
143.9
nmol/l
0.15
13
91
55
640
0.86
0.52
1.6
1.8
—
—
—
0
0
6
40
1.50
0.51
1.8
1.4
—
—
—
0
0
26
206
1.27
0.51
1.2
1.1
—
—
—
0
0
19
144
1.32
0.50
2.2
2.3
—
—
—
0
0
9
65
1.39
0.50
1.4
2.0
34.1
146.8
ug/l
—
9
54
128
1164
1.11
0.50
3.2
3.7
5.2
5.2
kpa
0.29
117
1081
6
41
1.46
0.50
1.0
1.3
—
—
—
0
0
6
41
1.46
0.50
1.0
1.2
—
—
—
0
0
36
298
1.21
0.49
1.5
1.5
—
—
—
0
0
85
953
0.89
0.49
3.7
3.6
—
—
—
0
0
409
3903
1.06
0.48
1.6
1.7
467.2
31258258.3
pmol/l
3.24
339
3196
126
1151
1.10
0.46
3.2
3.7
7.4
7.4
ph
—
10
150
33
396
0.83
0.45
3.8
3.7
26.0
26.0
mg/l
0.00
19
256
20
156
1.28
0.45
2.7
2.3
—
—
—
0
0
7
50
1.40
0.45
1.6
1.4
—
—
—
0
0
21
165
1.28
0.45
1.1
1.1
0.3
2.5
u/ml
—
5
40
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
16
208
0.77
0.44
1.3
1.2
—
—
—
0
0
31
257
1.21
0.43
2.6
2.5
—
—
—
0
0
31
371
0.83
0.42
1.4
1.8
0.8
0.8
nmol/l
0.00
25
306
33
276
1.20
0.42
2.2
1.4
—
—
—
0
0
16
122
1.31
0.42
2.1
2.1
4.0
1.9
ug/l
0.70
16
106
5
33
1.52
0.41
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
15
114
1.32
0.40
1.2
1.2
11.8
11.8
mmol/l
—
9
39
24
195
1.23
0.40
1.2
1.1
—
—
—
0
0
29
346
0.84
0.39
5.0
3.6
59.0
58.2
%
0.12
29
346
5
35
1.43
0.39
2.6
2.0
10.1
8.5
mg/l
—
5
29
0
19
0.00
0.39
0.0
1.7
—
0.4
—
0
12
12
159
0.75
0.38
1.1
1.0
—
—
—
0
0
41
472
0.87
0.37
3.3
3.2
25.0
25.1
mmol/l
0.02
32
412
28
333
0.84
0.37
4.9
3.2
4.7
4.3
e9/l
0.31
28
333
9
69
1.31
0.37
1.1
1.2
129.0
230.3
iu/ml
—
9
69
85
931
0.91
0.35
2.8
2.7
0.3
0.4
e6/l
0.03
80
906
16
201
0.79
0.35
2.8
6.4
7.6
7.4
mmol/l
—
10
172
6
44
1.36
0.34
1.0
1.1
—
—
—
0
0
6
44
1.36
0.34
1.0
1.1
—
—
—
0
0
6
44
1.36
0.34
1.0
1.1
—
—
—
0
0
36
415
0.87
0.34
5.6
4.9
2.8
2.7
mmol/l
0.12
22
292
6
46
1.31
0.33
1.8
5.1
—
—
—
0
0
22
183
1.20
0.31
1.7
1.4
—
—
—
0
0
23
273
0.84
0.31
1.2
1.1
54.9
73.6
iu/ml
—
9
60
7
53
1.32
0.30
1.0
1.0
—
—
—
0
0
7
55
1.27
0.30
1.4
1.3
—
—
—
0
0
12
93
1.29
0.30
2.3
1.7
0.5
2.6
u/field
—
6
71
23
194
1.19
0.29
1.5
1.5
—
—
—
0
0
10
130
0.77
0.29
1.1
1.1
—
—
—
0
0
11
85
1.30
0.28
1.3
1.2
—
—
—
0
0
17
140
1.22
0.27
1.1
1.0
1.2
3.2
u/ml
—
6
52
35
394
0.89
0.26
2.6
3.4
116.1
1007.8
u/ml
0.77
35
370
35
394
0.89
0.26
2.9
2.6
15.5
16.2
%
0.34
14
203
30
341
0.88
0.25
2.8
2.9
—
—
—
0
0
34
302
1.13
0.24
3.4
3.5
1.5
1.5
%
0.03
28
239
6
81
0.74
0.24
1.7
1.2
—
—
—
0
0
63
583
1.08
0.22
15.3
10.7
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
14.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
4.2
—
0
10
0
10
0.00
0.21
0.0
4.4
—
—
—
0
0
16
135
1.19
0.21
2.4
2.1
8.9
7.1
mmol/l
—
9
82
0
12
0.00
0.21
0.0
1.3
—
17.6
—
0
7
0
13
0.00
0.21
0.0
1.2
—
45.0
—
0
7
0
13
0.00
0.21
0.0
1.1
—
0.2
—
0
6
0
13
0.00
0.21
0.0
1.1
—
0.1
—
0
6
6
48
1.25
0.20
1.3
1.5
—
—
—
0
0
30
334
0.90
0.20
2.8
3.2
—
—
—
0
0
16
136
1.18
0.20
1.2
1.1
—
—
—
0
0
13
108
1.21
0.20
1.2
1.1
270.6
282.7
mg/l
0.12
13
95
6
50
1.20
0.19
1.3
1.2
—
—
—
0
0
10
81
1.24
0.18
8.7
13.4
—
—
—
0
0
15
174
0.86
0.17
1.1
1.1
—
—
—
0
0
104
991
1.05
0.17
1.3
1.3
—
—
—
0
0
7
61
1.15
0.17
2.9
2.4
—
—
—
0
0
8
69
1.16
0.16
1.1
1.4
—
—
—
0
0
9
83
1.08
0.14
1.1
1.1
—
—
—
0
0
24
217
1.11
0.14
2.8
2.6
—
—
—
0
0
8
96
0.83
0.13
2.9
2.5
—
—
—
0
0
16
180
0.89
0.13
1.4
2.2
—
—
—
0
0
44
413
1.07
0.13
2.5
3.1
7.9
8.0
kpa
0.17
37
378
353
3591
0.98
0.12
5.9
4.5
—
—
—
0
0
21
230
0.91
0.11
1.3
1.2
—
—
—
0
0
11
126
0.87
0.11
1.5
1.2
—
—
—
0
0
20
182
1.10
0.11
1.1
1.1
—
—
—
0
0
24
221
1.09
0.11
1.8
1.6
60.2
61.6
%
0.07
18
144
449
4544
0.98
0.09
4.6
4.2
0.0
0.0
estimate
1.08
115
1490
34
360
0.94
0.09
1.1
1.4
1328.0
999.2
e6/l
0.10
26
290
34
360
0.94
0.09
1.1
1.4
73.0
35.2
e6/l
0.23
26
274
5
62
0.81
0.08
1.4
1.1
1124.2
1674.5
miu/ml
—
5
62
38
362
1.05
0.07
1.6
1.5
122.2
256.4
pmol/l
1.58
38
357
11
98
1.12
0.07
2.6
3.0
—
—
—
0
0
30
317
0.95
0.07
1.6
1.7
—
—
—
0
0
9
87
1.03
0.07
1.0
1.2
293.9
396.7
u/l
—
9
79
11
101
1.09
0.04
1.5
1.2
—
—
—
0
0
14
131
1.07
0.03
1.1
1.1
1.9
3.4
u/ml
—
5
48
34
333
1.02
0.01
1.2
1.4
—
—
—
0
0
15
144
1.04
0.00
1.3
1.5
0.5
0.2
nmol/l
—
9
105
24
234
1.03
0.00
1.3
1.1
—
13.3
—
0
11
43
424
1.01
0.00
1.3
1.3
—
—
—
0
0
15
155
0.97
0.00
2.1
2.0
6.8
4.4
mg/l
0.39
15
149
11
109
1.01
0.00
1.1
1.1
—
—
—
0
0
15
149
1.01
0.00
2.1
2.0
2.3
2.1
u/field
—
6
59
46
456
1.01
0.00
2.2
2.3
79.8
90.4
ug/min
0.12
28
274
438
4384
1.00
0.00
1.4
1.3
—
—
—
0
0
5
51
0.98
0.00
2.2
1.4
40.8
23.8
%
—
5
34
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
5
56
0.89
0.00
1.0
1.1
—
1.4
—
0
21
6
69
0.87
0.00
1.5
1.3
—
—
—
0
0
8
81
0.99
0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
9
98
0.92
0.00
6.7
6.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
0.00
1.3
1.3
—
—
—
0
0
36
360
1.00
0.00
1.0
1.2
—
—
—
0
0
9
92
0.98
0.00
1.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
0.00
1.3
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
6
65
0.92
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_ORAL_LEUCOPLAC_RELAT and mortality.

Females

Parameter HR [95% CI] p-value
K11_ORAL_LEUCOPLAC_RELAT 1.15 [1.04, 1.27] 0.005
Birth year 0.994 [0.98, 1.0] 0.175

During the follow-up period (1.1.1998 — 31.12.2019), 1192 out of 5953 females with K11_ORAL_LEUCOPLAC_RELAT died.

Males

Parameter HR [95% CI] p-value
K11_ORAL_LEUCOPLAC_RELAT 1.278 [1.15, 1.42] < 0.001
Birth year 0.994 [0.98, 1.0] 0.25

During the follow-up period (1.1.1998 — 31.12.2019), 1068 out of 4459 males with K11_ORAL_LEUCOPLAC_RELAT died.

Mortality risk

Mortality risk for people of age

years, who have K11_ORAL_LEUCOPLAC_RELAT.

N-year risk Females Males
1 0.089% 0.354%
5 0.599% 1.888%
10 1.725% 4.593%
15 3.232% 8.523%
20 5.64% 14.425%

Relationships between endpoints

Index endpoint: K11_ORAL_LEUCOPLAC_RELAT – Oral leukoplakia and related diseases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data