Gestational [pregnancy-induced] hypertension

O15_GESTAT_HYPERT

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O13
  • Hospital discharge: ICD-9 6423
  • Hospital discharge: ICD-8 63701
  • Cause of death: ICD-10 O13
  • Cause of death: ICD-9 6423
  • Cause of death: ICD-8 63701

2 out of 7 registries used, show all original rules.

12340

4. Check minimum number of events

None

12340

5. Include endpoints

None

12340

6. Filter based on genotype QC (FinnGen only)

12340

Control definitions (FinnGen only)

Control exclude
O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O10-O16
Name in latin
Hypertensio gestationalis sine proteinuria significanti

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 88050 88050 -
Only index persons 86216 86216 -
Unadjusted period prevalence (%)
Whole population 2.52 2.52 -
Only index persons 3.17 3.17 -
Median age at first event (years)
Whole population - 29.58 -
Only index persons - 29.54 -

-FinnGen-

Key figures

All Female Male
Number of individuals 12340 12340 -
Unadjusted period prevalence (%) 4.21 4.21 -
Median age at first event (years) 29.74 29.74 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
11046
Matched controls
110149
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.5
323.0
3812
19266
205
Kela drug reimbursment
Chronic hypertension
3.5
323.0
1995
6538
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
8132.5
323.0
7568
23
6423A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, ENNEN SYNNYTYSTÄ]
+∞
323.0
1327
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
5609.1
323.0
1043
*
I10
ICD-10 Finland
Essential (primary) hypertension
2.5
323.0
4562
23847
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.0
323.0
2398
9291
C07AG01
ATC
labetalol; systemic
60.0
323.0
784
140
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.7
323.0
2708
11755
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
+∞
323.0
1181
*
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
754.4
323.0
841
12
O14.1
ICD-10 Finland
Severe pre-eclampsia
4772.2
323.0
469
*
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.1
323.0
2396
9116
63701
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Hypertonia
+∞
323.0
2223
*
63703
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia levis
+∞
272.7
261
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.6
263.9
2261
9851
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.2
256.2
3651
20477
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
3.1
250.1
1584
5690
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
2.0
242.7
4973
32184
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
+∞
236.0
226
*
C09AA02
ATC
enalapril; systemic
2.9
205.0
1411
5307
O16
ICD-10 Finland
Unspecified maternal hypertension
96.4
196.7
218
23
C08CA01
ATC
amlodipine; oral
2.2
193.7
2358
12047
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.0
189.4
1189
4194
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.0
186.8
2913
16508
O12.1
ICD-10 Finland
Gestational proteinuria
242.2
185.9
191
8
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.6
179.1
1448
5971
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
174.3
1393
5702
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.8
172.6
796
2213
XMA22
NOMESCO Finland
General examination of pregnant woman
2.4
156.9
1449
6397
6420X
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Benign essential hypertension complicating pregnancy, childbirth and the puerperium
+∞
154.3
148
*
O12.0
ICD-10 Finland
Gestational oedema
66.0
151.3
176
27
6423B
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, SYNNYTYKSEN AIKANA]
+∞
151.2
145
*
SPAT1379
SPAT
Health check-up of pregnant person
2.0
145.1
2375
13494
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.8
138.8
636
1751
ZXD05
NOMESCO Finland
Urgent procedure
1.7
136.8
3755
25296
W84
ICPC
Pregnancy high risk
2.9
131.7
856
3059
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
129.6
1889
10203
C08CA05
ATC
nifedipine; systemic
3.4
124.7
640
1930
C07AB02
ATC
metoprolol; systemic
2.2
122.7
1458
7209
A10BA02
ATC
metformin; oral
2.0
122.2
1858
10177
C07AB07
ATC
bisoprolol; oral
1.7
119.1
3267
21787
MAC96
NOMESCO Finland
Other induction or advancement of labour
3.1
116.4
682
2266
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.6
110.2
4982
37742
SPAT1197
SPAT
Extensive health check-up of expecting family
1.7
109.1
2611
16628
W78
ICPC
Pregnancy
1.7
108.4
2884
18955
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
4.1
106.1
434
1077
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.0
105.8
1445
7544
O10.9
ICD-10 Finland
Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
104.2
100
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.7
104.2
2902
19284
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.8
103.8
1997
11832
SPAT1380
SPAT
Postpartum check-up
1.8
103.2
1947
11456
C09BA02
ATC
enalapril and diuretics; systemic
3.5
102.3
513
1515
O11
ICD-10 Finland
Pre-eclampsia superimposed on chronic hypertension
+∞
99.0
95
*
C09CA06
ATC
candesartan; oral
1.8
97.7
2024
12258
40199
ICD-8 Finland
Essential benign hypertension
12.7
96.0
175
139
C09CA01
ATC
losartan; oral
1.9
94.8
1597
9003
63702
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Oedema
+∞
93.8
90
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.5
89.6
735
3000
K85
ICPC
Elevated blood pressure
2.1
86.8
1075
5358
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
86.2
1571
9078
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.8
85.5
1771
10672
63704
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia gravis
+∞
85.4
82
*
63700
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Albuminuria (proteinuria)
+∞
85.4
82
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
2.4
84.1
761
3273
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.5
83.0
703
2917
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
82.7
1537
8927
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.7
81.3
2113
13606
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
3.3
79.5
432
1355
SPAT1262
SPAT
Handing over of treatment supplies
1.9
77.4
1313
7374
W85
ICPC
Gestational diabetes
2.2
77.1
814
3769
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.7
76.6
1968
12608
C08CA13
ATC
lercanidipine; oral
2.2
76.1
798
3686
C09DA01
ATC
losartan and diuretics; oral
2.4
74.9
698
3042
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
74.7
1203
6629
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.0
74.3
1013
5239
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
2.0
73.5
994
5121
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.2
71.2
393
1247
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.4
68.4
613
2614
O61.0
ICD-10 Finland
Failed medical induction of labour
4.1
67.9
280
700
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.9
66.7
1101
6105
O60
ICD-10 Finland
Preterm labour and delivery
2.5
66.7
542
2195
6424B
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, SYNNYTYKSEN AIKANA]
+∞
66.6
64
*
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
3.0
66.1
404
1374
6425A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Severe pre-eclampsia[PRAE-ECLAMPSIA GRAVIS, ENNEN SYNNYTYSTÄ]
+∞
64.6
62
*
T90
ICPC
Diabetes non-insulin dependent
1.8
64.3
1290
7637
E66.9
ICD-10 Finland
Obesity, unspecified
2.6
63.1
476
1848
C03AA03
ATC
hydrochlorothiazide; oral
2.3
61.8
585
2566
O41.0
ICD-10 Finland
Oligohydramnios
2.8
61.4
422
1550
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.0
59.3
857
4517
C08CA02
ATC
felodipine; oral
2.5
59.2
475
1910
E66.8
ICD-10 Finland
Other obesity
2.1
58.3
721
3570
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.7
58.3
426
1622
C09AA05
ATC
ramipril; oral
1.8
56.6
1142
6753
B01AB05
ATC
enoxaparin; parenteral
1.5
55.5
2473
17930
SPAT1196
SPAT
Monitoring of normal pregnancy
1.7
54.9
1360
8544
O99.80
ICD-10 Finland
The fear of childbirth
1.8
53.7
939
5292
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.6
52.9
1493
9709
W92
ICPC
Compl labour/ delivery livebirth
2.5
52.6
421
1690
C09DA06
ATC
candesartan and diuretics; oral
2.3
51.9
486
2118
K86
ICPC
Hypertension uncomplicated
2.0
50.6
647
3245
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.5
49.7
399
1603
MAA00
NOMESCO Finland
Amniocentesis
2.4
48.8
442
1891
C02EA02
ATC
NA
4.4
47.7
178
406
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.5
47.4
378
1513
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
3.6
47.4
222
622
WX320
NOMESCO Finland
Spinalanesthesy
1.5
46.0
1965
14038
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.5
45.6
364
1459
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.1
45.1
527
2544
6425B
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Severe pre-eclampsia[PRAE-ECLAMPSIA GRAVIS, SYNNYTYKSEN AIKANA]
+∞
44.8
43
*
E66.00
ICD-10 Finland
Metabolic syndrome
2.3
44.7
438
1952
C02CB01
ATC
NA
35.7
44.3
57
16
J01DA01
ATC
[U] cefalexin; systemic
1.3
44.2
6574
57859
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.5
43.6
1545
10582
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.6
43.1
1119
7092
O10.1
ICD-10 Finland
Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium
+∞
42.7
41
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
42.4
4121
33966
C02AC05
ATC
moxonidine; oral
3.2
42.4
235
750
C09CA03
ATC
valsartan; oral
2.1
42.3
491
2362
J01DB01
ATC
cefalexin; oral
1.4
41.7
8697
80223
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.6
40.6
1253
8295
A10AE04
ATC
insulin glargine; parenteral
2.0
40.2
567
2952
Y6099
ICD-8 Finland
Prenatal care and observation
2.2
39.4
441
2086
N02BE01
ATC
paracetamol; systemic, rectal
1.4
38.9
8866
82288
C07AG02
ATC
carvedilol; oral
2.6
38.5
287
1105
O30.0
ICD-10 Finland
Twin pregnancy
2.5
38.5
322
1324
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
38.1
1519
10650
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.4
38.0
2218
16749
O12.2
ICD-10 Finland
Gestational oedema with proteinuria
377.7
38.0
38
*
C10AA01
ATC
simvastatin; oral
1.4
37.9
1833
13368
C03CA01
ATC
furosemide; systemic
1.6
37.6
1152
7602
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.3
37.5
373
1675
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
4.5
36.7
134
301
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.8
36.1
685
3951
O02.1
ICD-10 Finland
Missed abortion
1.6
36.0
933
5900
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
2.7
35.9
252
938
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
2.1
35.9
402
1905
A12BA01
ATC
potassium chloride; oral
3.2
35.9
193
604
SPAT1263
SPAT
Sampling
1.3
35.8
4180
35105
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.3
35.0
340
1509
W81
ICPC
Toxaemia of pregnancy
36.7
34.5
44
12
C07BB07
ATC
bisoprolol and thiazides; systemic
2.6
34.4
255
982
66120
ICD-8 Finland
Occipital presentation
14.2
34.0
58
41
MAX99
NOMESCO Finland
Assistance to normal delivery
1.4
33.8
1662
12129
4019X
ICD-9 Finland
Essential hypertension, Unspecified
5.4
33.6
103
192
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.9
33.5
505
2693
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
33.4
2705
21492
C09DA03
ATC
valsartan and diuretics; oral
2.5
33.3
266
1067
O32.1
ICD-10 Finland
Maternal care for breech presentation
1.7
33.3
744
4510
66180
ICD-8 Finland
Occipital presentation
2.9
32.6
208
733
8811
FHL
Cesarean section
1.8
32.5
638
3720
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.9
32.4
502
2707
A10BH01
ATC
sitagliptin; oral
2.0
32.2
448
2321
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.3
32.0
309
1370
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.5
31.7
1248
8704
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.5
31.1
1001
6671
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.7
30.8
744
4607
C07AB03
ATC
atenolol; systemic
2.3
30.7
289
1264
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.4
30.6
268
1130
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.8
30.1
202
734
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.6
29.9
858
5559
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
29.9
1128
7789
A10AE05
ATC
insulin detemir; parenteral
2.0
29.6
380
1906
W29
ICPC
Pregnancy symptom/complaint other
1.9
29.5
441
2346
C07AB08
ATC
celiprolol; oral
3.8
29.2
128
342
6462A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Unspecified renal disease in pregnancy, without mention of hypertension
+∞
29.1
28
*
C09AA03
ATC
lisinopril; oral
2.5
28.9
235
955
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
2.2
27.9
280
1262
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
27.6
350
1749
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
2.8
27.3
183
664
ZXE00
NOMESCO Finland
One hour or less
1.3
27.1
3933
33588
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
27.1
1051
7295
63799
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Toxaemia, unspecified
+∞
27.1
26
*
E66
ICD-10 Finland
Obesity
1.8
27.0
472
2650
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.6
26.9
702
4434
SGA01
NOMESCO Finland
Tooth opening as first aid
1.4
26.8
1673
12693
G47.3
ICD-10 Finland
Sleep apnoea
1.4
26.5
1286
9325
K02.1
ICD-10 Finland
Caries of dentine
1.2
26.3
6114
55049
O20.0
ICD-10 Finland
Threatened abortion
1.8
26.1
430
2367
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
25.9
1571
11848
A10BK03
ATC
empagliflozin; oral
1.9
25.3
380
2028
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
1.8
25.0
481
2785
MA3AE
NOMESCO Finland
Combined first trimester screening
1.6
25.0
678
4330
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
24.9
4186
36265
A10BJ06
ATC
semaglutide; parenteral
2.3
24.6
226
980
WX290
NOMESCO Finland
Other blockade of nerve
1.2
24.6
4983
44048
ZXD00
NOMESCO Finland
Emergency procedure
1.9
24.5
351
1837
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.5
24.1
195
792
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.6
23.9
677
4366
J01AA02
ATC
doxycycline; systemic
1.2
23.7
7783
72348
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
23.5
1005
7104
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
1.6
23.5
668
4314
C07FB02
ATC
metoprolol and felodipine; systemic
3.2
23.3
125
394
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.3
23.1
2015
16046
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.1
23.0
259
1233
C10AA05
ATC
atorvastatin; oral
1.3
22.9
1687
13105
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.0
22.8
300
1523
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.7
22.7
518
3157
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
2.6
22.7
172
675
R03.0
ICD-10 Finland
Elevated blood-pressure reading, without diagnosis of hypertension
1.9
22.5
357
1940
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
1.8
22.3
384
2144
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
22.3
5473
49155
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
3.1
22.3
126
413
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
3.0
22.2
134
456
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.0
22.2
306
1581
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.9
22.2
329
1748
SPAT1310
SPAT
Counselling related to known health issue
1.3
22.0
2830
23679
SPAT1301
SPAT
No procedures
1.3
22.0
2614
21665
O40
ICD-10 Finland
Polyhydramnios
2.4
21.9
193
822
6423C
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, SYNNYTYKSEN JÄLKEEN]
+∞
21.9
21
*
6461A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Oedema or excessive weight gain in pregnancy, without mention of hypertension
+∞
21.9
21
*
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.0
21.7
298
1538
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
21.6
6123
55710
O14
ICD-10 Finland
Pre-eclampsia
114.9
21.5
23
*
C09CA07
ATC
telmisartan; oral
1.8
21.5
382
2160
R51.80
ICD-10 Finland
Headache
1.3
21.3
1574
12222
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.0
21.3
264
1311
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.0
21.2
263
1304
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.2
21.1
223
1035
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
20.9
5024
44905
160
Kela drug reimbursment
exenatide
2.9
20.8
131
459
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.4
20.8
1085
7957
C08DB01
ATC
diltiazem; oral
2.4
20.7
185
792
WW200
SPAT
NA
1.4
20.7
981
7068
ZYC01
SPAT
NA
1.6
20.5
536
3389
Z37.0
ICD-10 Finland
Single live birth
1.3
20.5
1595
12477
W90
ICPC
Uncompl labour/delivery livebirth
1.5
20.4
702
4739
C10AA07
ATC
rosuvastatin; oral
1.4
20.4
1216
9126
R03AC02
ATC
salbutamol; inhalant
1.2
20.4
5394
48622
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
20.4
138
508
J01CA04
ATC
amoxicillin; systemic
1.3
20.1
8766
83059
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
20.1
472
2899
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
2.7
20.1
142
537
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
2.4
20.0
172
724
SPAT1097
SPAT
Recording of ECG
1.4
19.8
842
5942
K04.0
ICD-10 Finland
Pulpitis
1.4
19.8
1041
7644
C03BA11
ATC
indapamide; oral
2.6
19.6
145
560
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.8
19.6
347
1958
C09BA03
ATC
lisinopril and diuretics; oral
3.1
19.6
108
349
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
19.6
3694
32148
25009
ICD-8 Finland
Diabetes mellitus, Unspecified
5.4
19.3
58
108
SPAT1324
SPAT
Screening procedure
1.2
19.3
2815
23829
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.8
19.2
358
2055
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
1.8
19.2
315
1736
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.2
19.1
2627
22087
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
3.4
19.0
92
270
WX234
NOMESCO Finland
Paracervical blockade
1.6
18.9
450
2776
Z3232
NOMESCO Finland
Midwife
1.3
18.8
1465
11452
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
2.4
18.8
161
678
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
3.0
18.7
111
377
A10BJ02
ATC
liraglutide; parenteral
2.5
18.7
153
626
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
18.7
2365
19687
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.8
18.7
346
1984
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
18.6
430
2634
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
1.9
18.5
272
1443
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
2.4
18.3
152
630
Z30.2
ICD-10 Finland
Sterilization
1.3
18.3
1262
9682
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
2.2
18.2
185
846
SPAT1153
SPAT
Removal of sutures
1.3
18.1
2270
18866
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.6
17.9
480
3056
T82
ICPC
Obesity
1.7
17.8
390
2350
O15.0
ICD-10 Finland
Eclampsia in pregnancy
+∞
17.7
17
*
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
2.5
17.7
143
583
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.5
17.6
620
4206
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
2.2
17.5
184
853
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
1.9
17.3
256
1364
A46
ICD-10 Finland
Erysipelas
1.5
17.2
630
4311
6565A
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Poor foetal growth[SIKIÖN HIDASTUNUT INTRAUTERIININ KASVU,RASK AIK]
4.2
17.1
65
156
WX110
NOMESCO Finland
Local anesthesy
1.2
17.1
7172
66927
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
17.0
629
4309
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.3
17.0
157
684
A10BK01
ATC
dapagliflozin; oral
2.0
16.9
228
1170
O61.8
ICD-10 Finland
Other failed induction of labour
4.6
16.7
57
123
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
2.2
16.7
176
819
C07AB05
ATC
betaxolol; oral
2.7
16.5
113
422
C02LM02
ATC
NA
5.8
16.5
46
79
M04AA01
ATC
allopurinol; systemic
1.7
16.4
334
1971
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
16.4
7620
71611
QBJ30
NOMESCO Finland
Correction of abdominal apron
2.5
16.3
125
496
C10AX09
ATC
ezetimibe; oral
1.6
16.3
428
2712
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.6
16.3
416
2618
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
1.7
16.2
318
1859
A02BC01
ATC
omeprazole; systemic
1.2
16.2
2120
17679
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
16.0
1043
7924
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
16.0
2726
23376
SGB30
NOMESCO Finland
Other demanding filling of root channel of tooth
1.3
16.0
1193
9256
R09
ICPC
Sinus symptom/complaint
1.4
15.9
889
6591
G02BA03
ATC
plastic IUD with progestogen
1.3
15.8
1917
15833
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
15.8
5563
50941
ACC51
NOMESCO Finland
Release of median nerve
1.5
15.8
599
4132
A10BX04
ATC
[U] exenatide; parenteral
3.4
15.7
74
215
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
2.5
15.6
124
503
Z36.8
ICD-10 Finland
Other antenatal screening
1.7
15.6
321
1902
C07AB04
ATC
acebutolol; systemic
3.8
15.5
65
171
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
15.5
1408
11221
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
2.3
15.4
144
634
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.1
15.4
165
774
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
15.4
4153
37139
M54.5
ICD-10 Finland
Low back pain
1.2
15.3
3126
27252
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.4
15.3
128
532
H02AB06
ATC
prednisolone; systemic
1.2
15.2
4014
35821
SGC10
NOMESCO Finland
Covering pulpa of tooth
1.3
15.1
962
7281
O61.1
ICD-10 Finland
Failed instrumental induction of labour
4.0
15.0
60
152
C03DA01
ATC
spironolactone; oral
1.5
15.0
464
3063
C09DB01
ATC
valsartan and amlodipine; oral
2.4
14.9
125
522
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
14.7
3571
31608
C02DE04
ATC
NA
4.0
14.6
58
146
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
14.6
1452
11701
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.2
14.5
18
781
A10BB12
ATC
glimepiride; oral
2.0
14.5
188
957
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
14.4
2639
22746
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
1.3
14.4
1083
8405
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
2.7
14.4
95
349
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
3.0
14.4
83
279
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
14.3
813
6040
AN1
HP
Coronary angiography
1.7
14.3
291
1721
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
14.2
3270
28790
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
14.0
638
4559
B01AB04
ATC
dalteparin; parenteral
1.7
14.0
309
1868
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
14.0
1395
11246
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
2.9
13.9
82
281
B02AA02
ATC
tranexamic acid; systemic
1.2
13.8
1786
14842
H04AA01
ATC
glucagon; nasal, parenteral
1.9
13.8
213
1156
J01FF01
ATC
clindamycin; systemic
1.2
13.7
2210
18803
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.1
13.6
157
762
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
1.9
13.6
188
980
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
2.9
13.6
81
279
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
2.2
13.5
134
609
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
13.5
5071
46419
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.3
13.5
1057
8246
63710
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Eclampsia
+∞
13.5
13
*
N05AH02
ATC
clozapine; systemic
0.3
13.3
26
886
K04.08
ICD-10 Finland
Other specified pulpit
1.4
13.2
648
4698
N05AH03
ATC
olanzapine; systemic
0.6
13.2
225
3609
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
13.1
1395
11325
A10AA02
ATC
NA
1.8
13.0
220
1229
C07BB02
ATC
metoprolol and thiazides; systemic
3.2
13.0
68
215
W27
ICPC
Fear of complications of pregnancy
2.0
13.0
157
778
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.5
13.0
118
2221
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.6
12.9
302
1860
P01AB01
ATC
metronidazole; oral, rectal
1.2
12.9
4149
37474
G43.9
ICD-10 Finland
Migraine, unspecified
1.4
12.8
753
5626
J03.0
ICD-10 Finland
Streptococcal tonsillitis
1.6
12.8
326
2056
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
2.5
12.8
97
388
O72.0
ICD-10 Finland
Third-stage haemorrhage
1.6
12.7
311
1937
C08CA10
ATC
nilvadipine; oral
2.8
12.7
80
286
O85
ICD-10 Finland
Puerperal sepsis
2.1
12.7
145
701
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.5
12.7
392
2587
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
1.6
12.7
360
2331
R03BA05
ATC
fluticasone; inhalant
1.2
12.7
1631
13538
SPAT1283
SPAT
Restricted health certificate
1.2
12.6
2345
20197
C09DX01
ATC
valsartan, amlodipine and hydrochlorothiazide; oral
2.9
12.6
76
265
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
2.3
12.6
113
490
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.4
12.6
605
4371
T89
ICPC
Diabetes insulin dependent
1.7
12.5
274
1659
O10
ICD-10 Finland
Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
12.5
12
*
63709
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia NUD
+∞
12.5
12
*
A10AA01
ATC
NA
1.8
12.4
211
1185
M79.6
ICD-10 Finland
Pain in limb
1.2
12.4
3121
27614
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
12.3
718
5356
C09AA01
ATC
captopril; oral
3.8
12.3
50
130
A10BX07
ATC
[U] liraglutide; parenteral
2.8
12.3
76
268
G03GB02
ATC
clomifene; oral
1.6
12.2
292
1812
C09DA07
ATC
telmisartan and diuretics; oral
1.8
12.1
197
1087
E66.0
ICD-10 Finland
Obesity due to excess calories
2.7
12.1
81
301
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.5
12.1
415
2807
K04.09
ICD-10 Finland
Pulpit UNS
1.5
12.1
388
2585
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.7
12.1
296
4403
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
11.9
1587
13211
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
11.9
1868
15821
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
2.2
11.9
114
511
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
1.6
11.9
313
1990
C02EA03
ATC
NA
4.0
11.9
46
115
8221
FHL
Sterilization of the laparotomy pathway
1.7
11.8
238
1404
O47.9
ICD-10 Finland
False labour, unspecified
1.7
11.7
235
1388
H3600, E103
ICD-10 Finland
NA
2.3
11.6
104
451
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
11.6
6989
65927
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
11.4
2892
25571
C08CA03
ATC
isradipine; systemic
3.5
11.4
52
150
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
11.3
579
4230
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
1.9
11.3
150
774
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
11.2
807
6220
OAA41
SPAT
NA
2.1
11.2
122
580
SPAT1260
SPAT
Consultation of another employee
1.2
11.2
1356
11169
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.1
11.1
5131
47419
C01DA14
ATC
isosorbide mononitrate; oral
1.6
11.1
281
1767
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
2.7
11.1
72
265
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.5
11.1
421
2909
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
2.3
11.0
97
420
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.4
10.9
453
3189
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
3.2
10.9
56
177
SPAT1193
SPAT
Pap smear
1.2
10.8
1468
12244
ZXH06
SPAT
NA
1.8
10.7
183
1032
SPAT1312
SPAT
General health counselling
1.2
10.7
2913
25878
N02AX02
ATC
tramadol; systemic, rectal
1.2
10.6
3069
27377
MA3AE
SPAT
NA
2.7
10.6
69
254
O47
ICD-10 Finland
False labour
2.0
10.6
127
628
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
2.7
10.6
68
249
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.4
10.5
472
3369
MBA04
NOMESCO Finland
Curettage of uterus after delivery
2.3
10.5
97
430
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
3.3
10.5
52
160
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
10.5
492
3540
SPAT1388
SPAT
Extensive health check-up based on individual need
2.9
10.5
61
209
O36.4
ICD-10 Finland
Maternal care for intrauterine death
2.4
10.4
82
336
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
1.9
10.4
155
832
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
1.6
10.4
251
1560
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
2.1
10.4
117
567
C09AA04
ATC
perindopril; oral
1.7
10.4
191
1101
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.3
10.4
29
832
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.2
10.3
15
597
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
10.3
247
1536
-1
NOMESCO Finland
NA
1.2
10.3
3345
30092
C07AB12
ATC
nebivolol; oral
1.8
10.3
173
969
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.1
10.2
106
496
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
1.9
10.2
139
724
J01FA01
ATC
erythromycin; systemic
1.2
10.2
1549
13060
R75
ICPC
Sinusitis acute/chronic
1.4
10.1
468
3360
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
2.0
10.1
130
662
N97.9
ICD-10 Finland
Female infertility, unspecified
1.3
10.1
823
6455
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
10.0
1582
13385
MAB10
NOMESCO Finland
External version
2.1
10.0
106
500
OAA12
SPAT
NA
1.7
10.0
194
1140
KMAK
NOMESCO Finland
NA
1.1
9.8
5711
53420
J01CE02
ATC
phenoxymethylpenicillin; oral
1.1
9.7
7253
68945
M10.9
ICD-10 Finland
Gout, unspecified
1.9
9.7
137
722
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
9.7
430
3066
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
2.6
9.7
67
257
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
2.1
9.7
107
516
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.3
9.7
865
6868
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.4
9.7
400
2815
J01FA06
ATC
roxithromycin; oral
1.1
9.6
3715
33798
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.1
9.6
4026
36828
OAB42
SPAT
NA
1.5
9.6
361
2493
162
Kela drug reimbursment
liraglutide
2.7
9.6
63
235
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
2.1
9.6
103
490
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
1.9
9.6
132
694
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.5
9.5
88
1643
WZC30
NOMESCO Finland
Teaching
1.3
9.5
833
6600
R01AD09
ATC
mometasone; nasal
1.1
9.5
4807
44526
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.0
9.5
51
168
A10BJ01
ATC
exenatide; parenteral
2.8
9.4
57
202
XCK10
NOMESCO Finland
Photography of fundus of eye
1.4
9.4
489
3584
C02DE10
ATC
NA
4.3
9.4
33
76
WX725
NOMESCO Finland
Noninvasive ventilation
1.5
9.4
301
2005
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.3
9.4
85
375
R3110
NOMESCO Finland
Psychosocial training
1.6
9.4
211
1288
CK2S4
SPAT
NA
3.2
9.4
48
152
KAY40
NOMESCO Finland
NA
0.5
9.4
93
1706
Z71.8
ICD-10 Finland
Other specified counselling
1.2
9.4
2289
20120
OAA11
SPAT
NA
1.5
9.4
330
2247
O15.1
ICD-10 Finland
Eclampsia in labour
+∞
9.4
9
*
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
1.6
9.3
255
1641
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
1.5
9.3
278
1827
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
1.4
9.3
458
3328
A10BD07
ATC
metformin and sitagliptin; systemic
1.8
9.2
162
922
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
0.7
9.2
399
5379
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.2
9.2
1265
10556
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
1.5
9.2
339
2332
J01FA10
ATC
azithromycin; systemic
1.1
9.1
6292
59363
K04.1
ICD-10 Finland
Necrosis of pulp
1.3
9.1
864
6911
SGB20
NOMESCO Finland
Filling of root of tooth with 2 root channels
1.3
9.1
558
4200
R02
ICPC
Shortness of breath/dyspnoea
1.3
9.1
781
6169
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
2.1
9.1
102
496
LCA16
NOMESCO Finland
Destruction of endometrium
1.7
9.1
180
1064
G03FA01
ATC
norethisterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
0.8
9.0
602
7656
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
1.6
9.0
244
1565
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
1.9
9.0
130
696
WX704
NOMESCO Finland
Intubation
1.4
9.0
514
3828
6468B
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Other specified complications of pregnancy[RASKAUDENAIKAINEN LIIKALIHAVUUS]
9.0
9.0
18
20
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
9.0
1415
11966
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.3
9.0
652
5034
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
4.0
9.0
34
85
SPAT1192
SPAT
Gynaecological examination
1.2
9.0
1451
12303
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.0
8.9
49
164
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
1.9
8.8
126
670
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.2
8.8
1010
8259
B01AC04
ATC
clopidogrel; oral
1.4
8.8
383
2720
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
1.4
8.8
502
3737
A10AE06
ATC
insulin degludec; parenteral
1.7
8.8
188
1138
KAY20
NOMESCO Finland
NA
0.5
8.8
66
1307
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.3
8.8
772
6120
SPAT1316
SPAT
Extensive health check-up of children and adolescents
1.5
8.7
332
2297
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
2.3
8.7
76
330
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
1.9
8.7
127
683
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
8.7
2635
23534
N05AA02
ATC
levomepromazine; systemic
0.6
8.7
93
1665
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
1.6
8.7
231
1481
AA1AD
NOMESCO Finland
CT of head and brain
1.2
8.6
1222
10222
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.3
8.6
532
4017
SPAT1081
SPAT
Cardiorespiratory global assessment
1.5
8.5
245
1598
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
2.3
8.5
73
316
A10BB01
ATC
glibenclamide; oral
2.6
8.5
59
228
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.3
8.5
758
6018
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.1
8.4
3123
28272
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.2
8.4
1439
12255
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.9
8.4
115
605
SPAT1255
SPAT
Intravenous administration of medicine
1.4
8.4
362
2568
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.3
8.4
539
4089
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
1.8
8.4
145
824
WX600
NOMESCO Finland
Single shot through catheter
1.6
8.4
232
1499
SPAT1240
SPAT
Therapeutic discussion
1.2
8.4
1157
9657
C09BB04
ATC
perindopril and amlodipine; systemic
2.5
8.4
62
249
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.2
8.3
913
7429
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
8.3
554
4225
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.2
8.3
879
7126
I20.00
ICD-10 Finland
Unstable angina
2.5
8.3
64
261
MA5AE
SPAT
NA
2.5
8.3
64
261
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
1.8
8.2
137
771
SPAT1285
SPAT
Provision of consultation response
1.4
8.2
344
2430
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.7
8.2
155
907
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.3
8.2
611
4739
WX720
NOMESCO Finland
Own respiration
1.5
8.1
228
1478
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.5
8.1
308
2134
C09BB05
ATC
ramipril and felodipine; oral
5.6
8.1
22
39
6565B
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Poor foetal growth[SIKIÖN HIDASTUNUT INTRAUTERIININ KASVU,SYNN AIK]
3.8
8.1
32
84
R21
ICPC
Throat symptom/complaint
1.2
8.1
2252
19976
C02DB01
ATC
dihydralazine; systemic
17.1
8.0
12
7
SPAT1195
SPAT
Antenatal classes
1.4
8.0
410
3000
N05AX12
ATC
aripiprazole; systemic
0.7
8.0
174
2643
O21
ICD-10 Finland
Excessive vomiting in pregnancy
2.0
8.0
101
516
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
8.0
455
3389
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
8.0
2430
21686
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
2.1
8.0
89
433
A03
ICPC
Fever
1.2
8.0
1569
13534
A10BG03
ATC
pioglitazone; oral
2.1
7.9
87
421
P72
ICPC
Schizophrenia
0.4
7.9
29
741
J45.1
ICD-10 Finland
Nonallergic asthma
1.4
7.9
447
3325
R03BA02
ATC
budesonide; inhalant
1.2
7.9
1488
12782
C03EA02
ATC
trichlormethiazide and potassium-sparing agents; oral
2.3
7.9
71
314
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.7
7.9
51
189
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
7.9
9770
95324
A10BH02
ATC
vildagliptin; oral
2.4
7.9
63
264
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.5
7.9
239
1580
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
2.1
7.9
81
380
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.2
7.8
868
7075
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
7.8
493
3731
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.4
7.8
303
2108
R74
ICPC
Upper respiratory infection acute
1.1
7.8
3335
30443
W03
ICPC
Antepartum bleeding
1.9
7.8
105
548
G03FB05
ATC
norethisterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
0.8
7.8
496
6341
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.2
7.8
1083
9045
N02AA05
ATC
oxycodone; systemic
1.3
7.8
612
4779
R73.0
ICD-10 Finland
Abnormal glucose tolerance test
1.8
7.8
123
680
C07FB03
ATC
atenolol and nifedipine; systemic
9.4
7.7
15
16
SPAT1377
SPAT
Polysomnography
1.5
7.7
217
1411
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
3.5
7.7
34
98
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
4.0
7.7
29
73
CKC12
NOMESCO Finland
Photocoagulation of retina
1.5
7.7
220
1436
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
7.7
1786
15613
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
2.0
7.7
96
489
H03AA01
ATC
levothyroxine sodium; systemic
1.2
7.7
2189
19436
WX892
NOMESCO Finland
Monitored bed care
1.4
7.7
350
2513
F53.0
ICD-10 Finland
Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
3.1
7.6
40
131
177
Kela drug reimbursment
Insulin glargine 300 U / ml
1.8
7.6
114
620
MAB20
NOMESCO Finland
Failed external version
1.7
7.6
163
990
A08AB01
ATC
orlistat; oral
2.9
7.6
44
152
SPAT1236
SPAT
Informing family of child’s disability
1.8
7.6
123
685
J01CA08
ATC
pivmecillinam; oral
1.1
7.6
5030
47115
MAC00
NOMESCO Finland
Rupture of amniotic membrane
2.4
7.6
60
250
Z35.5
ICD-10 Finland
Supervision of elderly primigravida
2.1
7.6
77
362
XMA20
NOMESCO Finland
Early examination of pregnancy
1.7
7.6
162
981
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
1.6
7.6
167
1021
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
7.5
1352
11565
SPAT1391
SPAT
Counselling and guidance related to family situation
1.7
7.5
145
856
MAC02
NOMESCO Finland
Rupture of aminiotic membrane for advancement of labor
2.3
7.5
68
302
O90.2
ICD-10 Finland
Haematoma of obstetric wound
3.6
7.5
32
90
SGA03
NOMESCO Finland
Demanding opening and dilatation of root canal of tooth
1.2
7.5
834
6803
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
1.8
7.5
115
633
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.3
7.5
453
3412
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
1.9
7.4
100
523
WX780
NOMESCO Finland
Remote monitoring CPAP
1.6
7.4
203
1314
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
2.0
7.4
89
446
R06.5
ICD-10 Finland
Mouth breathing
1.3
7.4
479
3642
6563B
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Foetal distress[ASPHYXIA FOETALIS, SYNNYTYKSEN AIKANA]
1.6
7.4
164
1007
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.2
7.4
2022
17897
O84.8
ICD-10 Finland
Other multiple delivery
2.7
7.4
48
180
D10BA01
ATC
isotretinoin; oral
0.8
7.4
446
5736
C10AA04
ATC
fluvastatin; oral
1.5
7.3
249
1687
G03FA12
ATC
medroxyprogesterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
0.7
7.3
196
2855
-2
ICD-10 Finland
NA
0.6
7.3
81
1435
G03GA05
ATC
follitropin alfa; parenteral
1.4
7.3
396
2930
O10.3
ICD-10 Finland
Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium
+∞
7.3
7
*
6427A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Pre-eclampsia or eclampsia superimposed on pre-existing hypertension[PRAE-ECL SEU ECL CUM HYPERT ART,ENNEN SYNNYTYSTÄ]
+∞
7.3
7
*
O12
ICD-10 Finland
Gestational [pregnancy-induced] oedema and proteinuria without hypertension
+∞
7.3
7
*
I50.0
ICD-10 Finland
Congestive heart failure
1.8
7.3
109
593
N05AX08
ATC
risperidone; systemic
0.7
7.2
241
3385
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
1.5
7.2
201
1307
C09AA06
ATC
quinapril; systemic
4.0
7.2
27
68
W05
ICPC
Pregnancy vomiting/nausea
1.8
7.2
114
631
63501
ICD-8 Finland
Urinary infections arising during pregnancy and the puerperium, Pyelitis et pyelocystitis
3.7
7.2
29
78
W18
ICPC
Post-partum symptom/complaint other
2.1
7.2
79
385
R06.0
ICD-10 Finland
Dyspnoea
1.2
7.2
1587
13818
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.9
7.2
96
503
JDF01
NOMESCO Finland
Laparoscopic gastroplasty
2.3
7.2
60
257
R42
ICD-10 Finland
Dizziness and giddiness
1.2
7.1
1400
12064
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
1.5
7.1
236
1592
H3601, E113
ICD-10 Finland
NA
2.7
7.1
44
161
SPAT1373
SPAT
Combined screening in early pregnancy
1.5
7.1
230
1543
C02DE02
ATC
NA
3.5
7.1
31
89
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
1.8
7.1
119
672
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.3
7.1
474
3623
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
1.3
7.1
647
5156
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
0.4
7.1
24
632
I20.01
ICD-10 Finland
Unstable angina
2.5
7.1
51
204
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
3.2
7.1
35
111
EBA00
NOMESCO Finland
Extraction of tooth
1.1
7.1
2653
23995
B01AA03
ATC
warfarin; systemic
1.3
7.1
527
4093
S18
ICPC
Laceration/cut
1.1
7.0
2859
25982
63499
ICD-8 Finland
Other complications of pregnancy, Other
1.8
7.0
109
603
SPAT1325
SPAT
Vaccination
1.1
7.0
2328
20882
SPAT1054
SPAT
Examination of peripheral nervous system
2.1
7.0
72
339
A10BX01
ATC
guar gum; systemic
1.7
7.0
141
842
R03DC03
ATC
montelukast; oral
1.2
6.9
1473
12777
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
2.5
6.9
52
210
H3601, E103
ICD-10 Finland
NA
2.2
6.9
69
321
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
0.2
6.9
8
356
O62.0
ICD-10 Finland
Primary inadequate contractions
2.1
6.8
74
358
H01
ICPC
Ear pain/earache
1.2
6.8
946
7896
R2110
NOMESCO Finland
Giving the first information
1.2
6.8
721
5846
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.0
6.8
76
372
D68.8
ICD-10 Finland
Other specified coagulation defects
1.9
6.8
95
505
PEN23
NOMESCO Finland
Plastic repair of femoral artery
4.8
6.8
21
44
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
6.8
581
4591
N03AX12
ATC
gabapentin; oral
1.2
6.8
1091
9236
O75.3
ICD-10 Finland
Other infection during labour
3.3
6.8
31
93
K22
ICPC
Risk factor cardiovascular disease
1.5
6.8
205
1361
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.8
6.7
108
601
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.4
6.7
52
216
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
1.5
6.7
198
1302
WZC30
SPAT
NA
1.7
6.7
117
670
Z12
ICPC
Relationship problem with partner
1.5
6.7
193
1266
W30
ICPC
Pregnancy, Medical examin/health eval complete
1.9
6.7
86
446
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
2.1
6.6
70
338
O90.0
ICD-10 Finland
Disruption of caesarean section wound
3.5
6.5
28
80
G03DB01
ATC
dydrogesterone; oral
1.2
6.5
1759
15539
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.2
6.5
656
5297
J01
ICD-10 Finland
Acute sinusitis
1.3
6.5
480
3727
EMB10
NOMESCO Finland
Tonsillectomy
1.3
6.5
646
5207
K02
ICD-10 Finland
Dental caries
1.3
6.4
546
4315
H3603, E103
ICD-10 Finland
NA
2.0
6.4
75
373
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
2.4
6.4
50
209
SPAT1187
SPAT
General ultrasound examination in early pregnancy
1.7
6.4
123
726
SPAT1303
SPAT
Counselling and guidance related to growth and development
1.8
6.4
105
593
R03AK07
ATC
formoterol and budesonide; inhalant
1.2
6.4
1659
14624
LCA06
NOMESCO Finland
Biopsy of endometrium
1.2
6.3
1365
11852
SPAT1307
SPAT
Psychosocial counselling and guidance
1.3
6.3
642
5181
D07AC13
ATC
mometasone; topical
1.1
6.3
2394
21643
ZXE10
NOMESCO Finland
More than one and less than three hours
1.1
6.3
2808
25635
M54.3
ICD-10 Finland
Sciatica
1.3
6.3
391
2961
C09BA05
ATC
ramipril and diuretics; oral
2.0
6.3
74
371
O23.4
ICD-10 Finland
Unspecified infection of urinary tract in pregnancy
2.9
6.3
34
116
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
1.6
6.3
149
934
SPAT1383
SPAT
Extensive health check-up at 4 years of age
1.7
6.3
122
724
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
1.5
6.3
228
1572
207
Kela drug reimbursment
Chronic arrhythmias
1.4
6.3
328
2418
6422X
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Other pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
6.2
6
*
XF600
NOMESCO Finland
Bloodpressure measurement
1.4
6.2
329
2426
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
1.4
6.2
325
2393
ZY010
SPAT
NA
2.1
6.2
65
312
W99
ICPC
Disorder of pregn/delivery other
2.3
6.2
54
238
SFC92
NOMESCO Finland
Other demanding adjuvant procedure of filling therapy
1.3
6.2
384
2906
N97.0
ICD-10 Finland
Female infertility associated with anovulation
1.4
6.2
271
1938
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.3
6.2
394
2997
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
1.5
6.2
193
1290
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.9
6.2
84
446
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.1
6.1
1760
15615
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
1.6
6.1
148
933
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.3
6.1
392
2981
O03
ICD-10 Finland
Spontaneous abortion
2.0
6.1
73
369
Z29
ICPC
Social problem NOS
1.6
6.1
154
982
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
1.7
6.1
108
623
O28.0
ICD-10 Finland
Abnormal haematological finding on antenatal screening of mother
3.1
6.1
30
96
XMA00
NOMESCO Finland
NA
2.0
6.1
71
357
H36.01
ICD-10 Finland
Diabetic maculopathy
2.2
6.1
54
242
H01CA02
ATC
nafarelin; nasal
1.3
6.1
357
2680
Z30.5
ICD-10 Finland
Surveillance of (intrauterine) contraceptive device
1.2
6.1
905
7613
ZYC01
NOMESCO Finland
Remote contact by phone
1.4
6.1
329
2442
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
3.0
6.1
31
102
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.1
6.0
5719
54324
P02
ICPC
Acute stress reaction
1.3
6.0
507
4000
ZXA10
NOMESCO Finland
Bilateral
1.2
6.0
1176
10130
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
1.4
6.0
228
1584
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.2
6.0
956
8087
C02EA05
ATC
NA
4.9
6.0
18
37
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.3
6.0
413
3174

Mortality – FinRegistry

Association

Association between endpoint O15_GESTAT_HYPERT and mortality.

Females

Parameter HR [95% CI] p-value
O15_GESTAT_HYPERT 0.601 [0.52, 0.7] < 0.001
Birth year 0.996 [0.99, 1.0] 0.39

During the follow-up period (1.1.1998 — 31.12.2019), 332 out of 52846 females with O15_GESTAT_HYPERT died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_GESTAT_HYPERT.

N-year risk Females Males
1 0.07% No data
5 0.382% No data
10 0.969% No data
15 1.82% No data
20 3.187% No data

Relationships between endpoints

Index endpoint: O15_GESTAT_HYPERT – Gestational [pregnancy-induced] hypertension

GWS hits: 20

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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