Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

C3_PROSTATE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C61
  • Hospital discharge: ICD-9 185
  • Hospital discharge: ICD-8 185
  • Cause of death: ICD-10 C61
  • Cause of death: ICD-9 185
  • Cause of death: ICD-8 185
  • KELA reimbursements: KELA codes 116
  • Cancer registry: Topography ICD-O-3 C61
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

4 out of 7 registries used, show all original rules.

20966

4. Check minimum number of events

None

20966

5. Include endpoints

None

20966

6. Filter based on genotype QC (FinnGen only)

20966

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 20966 - 20966
Unadjusted period prevalence (%) 9.24 - 9.24
Median age at first event (years) 69.21 - 69.21

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3955
Matched controls
32975
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L02BB03
ATC
bicalutamide; oral
+∞
323.0
444
*
L02BX02
ATC
degarelix; parenteral
+∞
323.0
342
*
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
26.4
323.0
1553
787
XX3DW
NOMESCO Finland
Time consuming IT work
16.3
323.0
1064
726
ZXC96
NOMESCO Finland
Robot assisted procedure
295.5
323.0
1083
42
C61
ICD-10 Finland
Malignant neoplasm of prostate
4503599627370496.0
323.0
3891
11
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
10.5
323.0
1910
2697
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
323.0
420
*
Y77
ICPC
Malignant neoplasm prostate
3474.1
323.0
709
*
TKE00
NOMESCO Finland
Needle biopsy of prostate
17.7
323.0
566
308
R86.0
ICD-10 Finland
Abnormal findings in specimens from male genital organs, abnormal level of enzymes
25.4
323.0
698
276
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
79.7
323.0
2276
551
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
149.0
323.0
619
41
WF002
NOMESCO Finland
Radical radiotherapy
841.5
323.0
1099
15
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
323.0
1678
*
XKD00
NOMESCO Finland
Uroflowmetry
12.2
323.0
2312
3406
NK6AN
NOMESCO Finland
Total body bone isotope imaging
357.1
323.0
525
14
116
Kela drug reimbursment
Prostate cancer
+∞
323.0
1434
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
323.0
877
*
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
6.7
323.0
1193
1987
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
5527.7
323.0
578
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
6043.8
323.0
623
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
323.0
3927
*
KC1GB
NOMESCO Finland
Cystography with X-ray
289.6
323.0
375
12
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.6
323.0
1790
4982
H02AB02
ATC
dexamethasone; systemic
33.3
304.9
426
119
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
709.2
301.1
314
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
359.0
299.5
319
8
G04BE03
ATC
sildenafil; oral
41.2
297.9
397
89
JN4BD
NOMESCO Finland
Extensive body CT
8.9
297.6
706
783
KE1DG
NOMESCO Finland
Very extensive MRI of prostate
32.3
289.9
408
117
J01EA01
ATC
trimethoprim; systemic
7.0
287.2
805
1155
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
447.3
282.8
299
6
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
279.5
284
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
279.5
284
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
2312.1
261.2
268
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
803.7
259.2
270
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
2274.1
257.2
264
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
255.6
260
*
G04BE01
ATC
alprostadil; parenteral, urethral
28.7
253.2
367
117
163
Kela drug reimbursment
Abiraterone and enzalutamide
+∞
237.7
242
*
KE1BG
NOMESCO Finland
MRI of prostate
37.9
229.4
311
74
JN4AD
NOMESCO Finland
Body CT examination
9.4
225.3
511
511
KDE20
NOMESCO Finland
Removal of foreign body from urethra
71.6
223.9
272
34
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
162.2
213.0
238
13
A04AA02
ATC
granisetron; systemic, transdermal
279.4
203.4
220
7
D40.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Prostate
26.7
195.8
289
97
L02BB04
ATC
enzalutamide; oral
+∞
195.0
199
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
194.0
198
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
1595.5
184.9
191
*
L02AE04
ATC
triptorelin; parenteral
+∞
181.2
185
*
KE1CG
NOMESCO Finland
Extensive MRI of prostate
43.8
173.2
228
46
130
Kela drug reimbursment
Malignant tumour
+∞
169.3
173
*
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
24.8
168.7
254
91
XJH00
NOMESCO Finland
Transanal ultrasonography
5.7
165.0
530
868
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
164.6
1312
4790
KEB00
NOMESCO Finland
Biopsy of prostate
38.2
163.4
221
51
B01AB05
ATC
enoxaparin; parenteral
2.8
157.5
1308
4873
352
Kela drug reimbursment
Abiraterone and enzalutamide
+∞
156.5
160
*
M05BX04
ATC
denosumab; parenteral
22.8
153.6
237
92
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.3
153.5
954
2908
WZC30
NOMESCO Finland
Teaching
3.9
147.9
715
1775
G04CA02
ATC
tamsulosin; oral
2.5
146.4
1599
6935
TKW99
NOMESCO Finland
Other minor surgical procedure in urology
39.0
145.6
196
44
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
143.7
147
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.6
141.5
561
1152
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
11.7
136.7
273
208
L03AA13
ATC
pegfilgrastim; parenteral
1191.4
131.7
137
*
UKC02
NOMESCO Finland
Cystoscopy
3.2
131.2
837
2565
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
1181.2
130.8
136
*
ZX080
NOMESCO Finland
Image guided radiotherapy
576.6
127.0
134
*
WF090
NOMESCO Finland
Profylactic radiotherapy
+∞
123.0
126
*
N40
ICD-10 Finland
Hyperplasia of prostate
2.4
122.0
1447
6394
TKE10
NOMESCO Finland
Puncture of prostate
229.9
121.5
133
5
J01MA02
ATC
ciprofloxacin; systemic
2.3
121.3
1742
8454
N39.3
ICD-10 Finland
Stress incontinence
85.7
117.1
139
14
WX402
NOMESCO Finland
General anaesthesia
3.0
115.8
820
2672
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
271.0
115.2
125
*
L02BX03
ATC
abiraterone; oral
+∞
115.2
118
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
113.2
116
*
G04BE30
ATC
drugs used in erectile dysfunction - combinations
338.9
110.8
119
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
259.4
110.3
120
*
OAB42
NOMESCO Finland
Guidance related to known health problem
120.5
109.9
126
9
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
107.3
110
*
TQW40
NOMESCO Finland
Remowal of suture of skin
4.1
106.3
465
1035
WF004
NOMESCO Finland
Palliative radiotherapy
933.2
104.3
109
*
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
13.2
95.8
180
119
PJD54
NOMESCO Finland
Block dissection of iliac lymph nodes
+∞
95.5
98
*
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
218.3
93.0
102
*
3054
Kela drug reimbursment
NA
+∞
92.6
95
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
92.6
95
*
1523
Kela drug reimbursment
NA
+∞
91.6
94
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
89.7
92
*
Z51.5
ICD-10 Finland
Palliative care
13.2
87.4
164
108
N02BE01
ATC
paracetamol; systemic, rectal
2.2
82.1
3263
22499
JN4LR
NOMESCO Finland
Extensive PET-CT of receptors in whole body
705.5
79.0
83
*
Z51.0
ICD-10 Finland
Radiotherapy session
688.1
77.0
81
*
TKC52
NOMESCO Finland
Patient education concerning pelvic floor contraction exercises
174.4
73.7
82
*
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
224.4
72.1
79
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
72.1
74
*
JN4CD
NOMESCO Finland
Very extensive body CT
7.6
69.1
174
199
ZX112
NOMESCO Finland
Subcutaneous
14.1
69.0
125
76
N42.9
ICD-10 Finland
Disorder of prostate, unspecified
6.8
67.4
182
231
ZX020
NOMESCO Finland
HDR radiotherapy within tissue
+∞
65.2
67
*
K62.7
ICD-10 Finland
Radiation proctitis
+∞
65.2
67
*
PJD44
NOMESCO Finland
Excision of iliac lymph nodes
575.4
64.4
68
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
290.6
63.9
69
*
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
+∞
63.3
65
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
60.5
1780
10435
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
41.9
60.0
79
16
A04AA01
ATC
ondansetron; systemic, rectal
7.8
59.8
147
162
G04BD12
ATC
mirabegron; oral
3.0
57.3
373
1114
R31
ICD-10 Finland
Unspecified haematuria
2.6
55.4
448
1529
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
54.4
1564
9003
A79
ICPC
Malignancy NOS
246.6
53.3
58
*
Y06
ICPC
Prostate symptom/complaint
4.0
53.0
228
492
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
16.0
52.4
90
48
L02AE03
ATC
goserelin; implant
454.9
50.8
54
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
38.4
50.8
68
15
U04
ICPC
Incontinence urine
6.5
50.6
140
184
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
50.6
52
*
TKC20
NOMESCO Finland
Catheterisation of bladder
3.1
50.3
304
860
ZX050
NOMESCO Finland
Stereotactic radiotherapy
45.9
50.3
65
12
N02AA05
ATC
oxycodone; systemic
2.6
48.8
413
1441
C77.5
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrapelvic lymph nodes
+∞
47.6
49
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
20.9
47.4
74
30
G03HA01
ATC
cyproterone; systemic
31.1
47.1
66
18
KCC10
NOMESCO Finland
Cystoprostatectomy
215.5
46.6
51
*
JN2DM
NOMESCO Finland
Lower part of abdomen very extensive MRI examination with Tesla magnet
67.7
46.1
56
7
KD1GB
NOMESCO Finland
Uretrocystogpaphy with X-ray
39.7
46.0
61
13
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
45.7
47
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
45.7
47
*
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
+∞
45.7
47
*
L01BC06
ATC
capecitabine; oral
+∞
45.7
47
*
B01AB10
ATC
tinzaparin; parenteral
3.6
45.0
220
530
WB221
NOMESCO Finland
Demanding neoadjuvant hormone therapy of malignancy
+∞
43.8
45
*
KDG43
NOMESCO Finland
Transobturatorial sling urethrocystopexy
+∞
43.8
45
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
43.8
45
*
R33
ICD-10 Finland
Retention of urine
2.7
43.4
333
1096
XX1AD
NOMESCO Finland
Other CT-examination
73.2
43.3
52
6
KE1DR
NOMESCO Finland
Prostate metabolic PET with CT
+∞
42.8
44
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
103.4
42.4
49
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
369.2
41.2
44
*
L03AA02
ATC
filgrastim; parenteral
47.8
39.9
51
9
A04AD12
ATC
aprepitant; systemic
+∞
39.9
41
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
38.4
395
1520
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
37.9
39
*
XKG00
NOMESCO Finland
Artificial induction of erection
29.8
37.6
53
15
G04CA01
ATC
alfuzosin; oral
1.8
37.3
809
4166
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
326.5
36.4
39
*
JN2BG
NOMESCO Finland
MRI examination of lower part of abdoment with high intensity magnet
34.4
36.0
49
12
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
36.0
37
*
KDW96
NOMESCO Finland
Other operations on urethra
72.5
35.8
43
5
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.0
35.6
153
330
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
47.4
35.2
45
8
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
309.4
34.4
37
*
J01MA12
ATC
levofloxacin; systemic
1.8
34.0
649
3192
XX7FT
NOMESCO Finland
Radioyttrium therapy with connected antibody
+∞
34.0
35
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
34.0
35
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
109.4
34.0
39
*
TKC22
NOMESCO Finland
Catheterisation instruction
4.2
33.7
135
273
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
300.9
33.5
36
*
WVA20
NOMESCO Finland
Medicine administration
4.6
33.2
123
230
G04BD08
ATC
solifenacin; oral
3.1
32.5
195
548
Z12.5
ICD-10 Finland
Special screening examination for neoplasm of prostate
8.6
32.5
74
73
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
32.1
33
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
48.1
31.4
40
7
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
11.8
31.1
60
43
2BX02
NOMESCO Finland
NA
+∞
31.1
32
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
31.1
32
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
31.1
32
*
G04BE09
ATC
vardenafil; oral
46.9
30.5
39
7
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
46.9
30.5
39
7
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
266.8
29.6
32
*
R86.1
ICD-10 Finland
Abnormal findings in specimens from male genital organs, abnormal level of hormones
10.7
28.3
57
45
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
28.2
29
*
A06AH03
ATC
naloxegol; oral
19.5
27.9
44
19
R74.9
ICD-10 Finland
Abnormal level of unspecified serum enzyme
10.7
27.9
56
44
Z08.1
ICD-10 Finland
Follow-up examination after radiotherapy for malignant neoplasm
253.6
27.7
30
*
ZXC20
NOMESCO Finland
Use of chemical agents
8.9
27.0
60
57
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
26.2
27
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.6
26.1
80
122
WW500
NOMESCO Finland
Blood transfusion
4.4
25.6
98
191
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
25.3
26
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
25.3
26
*
WF099
NOMESCO Finland
Other radiotherapy
25.2
24.7
36
12
KED22
NOMESCO Finland
Transurethral resection of prostate
2.4
24.6
223
803
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
10.3
24.5
50
41
WX704
NOMESCO Finland
Intubation
2.2
24.3
254
977
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
5.4
24.0
75
117
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
23.8
244
932
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
23.3
24
*
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
209.8
22.9
25
*
XKD03
NOMESCO Finland
Urethral pressure profilometry
5.2
22.5
72
116
1CD02
NOMESCO Finland
NA
+∞
22.3
23
*
ZX022
NOMESCO Finland
LDR radiotherapy within tissue
+∞
22.3
23
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
22.1
656
3635
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
72.7
21.8
26
*
XKW99
NOMESCO Finland
Other physiological examination of urinary or male genital system
5.2
21.7
70
114
KE002
NOMESCO Finland
Radical radiotherapy of prostata and seminal vesicles
+∞
21.4
22
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
21.4
22
*
WVA30
NOMESCO Finland
Intramuscular and subcutaneous injection
19.8
21.2
33
14
PJA12
NOMESCO Finland
Sentinel node biopsy
192.8
21.0
23
*
KE1DM
NOMESCO Finland
Very extensive MRI of prostate (more than 1.5 T)
69.9
20.9
25
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
20.4
21
*
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
5.7
20.2
60
89
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
184.3
20.0
22
*
XX3AT
NOMESCO Finland
Other labeling with ultrasound guidance
18.6
19.6
31
14
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
175.9
19.1
21
*
WX110
NOMESCO Finland
Local anesthesy
1.4
18.9
2340
16994
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
18.8
270
1189
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
18.5
173
634
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
18.4
19
*
N30.4
ICD-10 Finland
Irradiation cystitis
+∞
18.4
19
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.7
18.0
509
6050
KBJ60
NOMESCO Finland
Anastomosis of ureter to urethra with interposition of ileum
+∞
17.5
18
*
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
17.5
18
*
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
+∞
17.5
18
*
R4110
NOMESCO Finland
Physiotherapy
1.5
17.4
825
5054
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
17.4
247
1084
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
18.9
17.2
27
12
KE1AE
NOMESCO Finland
Percutaneous utlrasound examination fo prostata
8.2
17.1
39
40
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
17.0
318
1537
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.9
16.9
106
308
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
16.7
102
293
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
25.1
16.7
24
8
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
79.6
16.2
19
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.2
16.1
63
127
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
15.8
316
1558
XX1XQ
NOMESCO Finland
Other SPECT-CT
+∞
15.5
16
*
OAB77
NOMESCO Finland
Discussion on exercise habits and instruction concerning use of sports and fitness services
+∞
15.5
16
*
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
+∞
15.5
16
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
53.0
15.4
19
*
NK6SN
NOMESCO Finland
Bone SPECT
75.4
15.3
18
*
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
23.0
15.0
22
8
TJF80
NOMESCO Finland
Ostomy education
10.6
14.7
29
23
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
14.6
15
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
133.9
14.3
16
*
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
14.1
141
536
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
14.1
1388
9570
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
14.1
522
3025
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
37.6
13.8
18
*
ZX100
NOMESCO Finland
Oral
4.7
13.7
47
84
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
13.6
14
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
13.6
14
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
13.6
14
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
13.6
14
*
XKC03
NOMESCO Finland
Water cystometry
2.9
13.5
82
235
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.5
13.5
111
381
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
125.5
13.4
15
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
125.5
13.4
15
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.2
13.3
143
562
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
30.1
13.2
18
5
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
6.4
13.2
35
46
KA3EB
NOMESCO Finland
Antegrade pyelography
8.4
12.6
28
28
C61, D400
ICD-10 Finland
NA
+∞
12.6
13
*
KE2KT
NOMESCO Finland
Marker implantation in prostate under radiological guidance
+∞
12.6
13
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
12.6
13
*
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
+∞
12.6
13
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.6
12.6
58
137
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
62.8
12.5
15
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
12.4
188
847
N99.1
ICD-10 Finland
Postprocedural urethral stricture
8.1
12.4
28
29
JN6AD
NOMESCO Finland
CT of torso and neck
7.6
12.3
29
32
R50.9
ICD-10 Finland
Fever, unspecified
1.6
12.3
342
1850
R86.9
ICD-10 Finland
Abnormal findings in specimens from male genital organs, unspecified abnormal finding
13.5
12.0
21
13
OAB75
NOMESCO Finland
Nutritional guidance related to maintaining health
41.8
11.8
15
*
WVA30
SPAT
NA
2.3
11.7
112
418
D07.5
ICD-10 Finland
Carcinoma in situ: Prostate
+∞
11.6
12
*
KE2JT
NOMESCO Finland
Demanding radiation source placement in prostate under ultrasound guidance
+∞
11.6
12
*
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
+∞
11.6
12
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
+∞
11.6
12
*
XX7AT
NOMESCO Finland
Radiation therapy with Radium-223
+∞
11.6
12
*
U76
ICPC
Malignant neoplasm of bladder
108.7
11.5
13
*
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
5.2
11.4
35
56
ZX136
NOMESCO Finland
Intravesicalis
11.7
11.3
21
15
SPAT1262
SPAT
Handing over of treatment supplies
1.4
11.2
630
3954
U08
ICPC
Urinary retention
2.9
11.1
68
197
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
11.1
93
1495
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
11.0
11.0
21
16
KCW96
NOMESCO Finland
Other operations on bladder
8.4
10.9
24
24
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
10.7
261
1365
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
54.3
10.7
13
*
U77
ICPC
Malignant neopl urinary tract other
+∞
10.7
11
*
YN1AD
NOMESCO Finland
CT examination of extremities for dose design of radiotherapy
+∞
10.7
11
*
KDK10
NOMESCO Finland
Implantation of artificial urinary sphincter around bulbar urethra
+∞
10.7
11
*
WB211
NOMESCO Finland
Neoadjuvant hormone therapy of malignancy
+∞
10.7
11
*
WB201
NOMESCO Finland
Simple neoadjuvant hormone therapy of malignancy
+∞
10.7
11
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
10.7
111
430
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.2
10.6
11
444
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
11.2
10.6
20
15
C90.0
ICD-10 Finland
Multiple myeloma
100.3
10.6
12
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
100.3
10.6
12
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
100.3
10.6
12
*
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
10.5
674
7095
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
10.4
87
305
G04CB02
ATC
dutasteride; oral
1.6
10.3
249
1298
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.7
10.2
196
958
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
20.9
10.1
15
6
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
4.8
10.0
33
58
KA1FN
NOMESCO Finland
Isotope renography
5.7
9.9
28
41
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.7
9.9
447
4948
KE2AT
NOMESCO Finland
Cytologoy of prostata with ultrasound guidance
50.1
9.8
12
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
6.9
9.8
24
29
L02BB01
ATC
flutamide; oral
+∞
9.7
10
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
9.7
10
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
9.7
10
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
9.7
10
*
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
+∞
9.7
10
*
Z08.8
ICD-10 Finland
Follow-up examination after other treatment for malignant neoplasm
91.9
9.6
11
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
14.9
9.6
16
9
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.5
9.6
338
1933
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
9.6
68
219
N48.4
ICD-10 Finland
Impotence of organic origin
1.9
9.4
137
613
WX600
NOMESCO Finland
Single shot through catheter
6.5
9.4
24
31
N05AA02
ATC
levomepromazine; systemic
0.4
9.2
51
938
ZX120
NOMESCO Finland
Intravenous
1.7
9.2
200
1016
N35.9
ICD-10 Finland
Urethral stricture, unspecified
2.8
9.0
57
171
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
6.4
8.9
23
30
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
7.3
8.9
21
24
B01AC04
ATC
clopidogrel; oral
0.7
8.9
304
3530
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.8
8.8
668
6898
C67
ICD-10 Finland
Malignant neoplasm of bladder
+∞
8.7
9
*
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
+∞
8.7
9
*
D63.0
ICD-10 Finland
Anaemia in neoplastic disease
+∞
8.7
9
*
ZX137
NOMESCO Finland
To penis
+∞
8.7
9
*
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
+∞
8.7
9
*
4194
NOMESCO Finland
NA
83.6
8.7
10
*
WF001
NOMESCO Finland
Preoperative radiotherapy
83.6
8.7
10
*
N30.9
ICD-10 Finland
Cystitis, unspecified
2.6
8.7
63
206
N05AX08
ATC
risperidone; systemic
0.5
8.6
58
995
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
0.3
8.6
16
464
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.2
8.5
12
403
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
5.6
8.4
24
36
U06
ICPC
Haematuria
2.6
8.4
61
200
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
0.5
8.3
69
1105
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
0.3
8.1
22
534
N05AC02
ATC
thioridazine; oral
0.2
8.1
11
378
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
20.1
8.1
12
5
OAA41
NOMESCO Finland
Health check based on individual needs
41.8
8.0
10
*
A10AA02
ATC
NA
0.3
7.9
19
487
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.0
7.9
104
449
WW200
SPAT
NA
0.7
7.8
180
2246
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
75.2
7.8
9
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
75.2
7.8
9
*
C77.9
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph node, unspecified
75.2
7.8
9
*
N42.8
ICD-10 Finland
Other specified disorders of prostate
4.1
7.8
29
59
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
7.8
8
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
7.8
8
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
7.8
8
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
7.8
8
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
7.8
8
*
KCC20
NOMESCO Finland
Cystoprostatourethrectomy
+∞
7.8
8
*
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
+∞
7.8
8
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
+∞
7.8
8
*
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
+∞
7.8
8
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
7.8
8
*
WD215
NOMESCO Finland
Multiple therapy of methastized malignancy with hormones
+∞
7.8
8
*
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
+∞
7.8
8
*
5BX04
NOMESCO Finland
NA
+∞
7.8
8
*
KWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in urological surgery
8.9
7.7
16
15
Y83.6
ICD-10 Finland
Removal of other organ (partial) (total) as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
23.0
7.7
11
*
ECB20
NOMESCO Finland
Oral alveoplasty
3.1
7.7
40
107
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
7.7
3379
26997
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
16.7
7.6
12
6
N03AG01
ATC
valproic acid; systemic, rectal
0.5
7.6
61
992
P72
ICPC
Schizophrenia
0.2
7.6
10
349
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
14.3
7.3
12
7
SPAT1153
SPAT
Removal of sutures
1.2
7.2
923
6465
WX320
NOMESCO Finland
Spinalanesthesy
1.3
7.2
615
4096
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
0.5
7.2
64
1004
A10BA02
ATC
metformin; oral
0.8
7.2
735
7345
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
3.4
7.1
33
82
TQX05
NOMESCO Finland
Skin puncture, unspecified location
8.4
7.1
15
15
U99
ICPC
Urinary disease other
4.5
7.0
24
45
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
6.8
7.0
17
21
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
6.8
7.0
17
21
U28
ICPC
Limited function/disability (U)
3.8
6.9
28
62
N05AB03
ATC
perphenazine; systemic, rectal
0.4
6.9
33
633
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
0.5
6.8
53
868
C07AB07
ATC
bisoprolol; oral
0.8
6.8
1196
11339
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
+∞
6.8
7
*
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
+∞
6.8
7
*
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
+∞
6.8
7
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
6.8
7
*
8000/3-C61.9
ICD-O-3
Neoplasm, malignant of prostate gland
+∞
6.8
7
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
6.8
7
*
8090/3-C44.6
ICD-O-3
Basal cell carcinoma, NOS, of skin of upper limb and shoulder
+∞
6.8
7
*
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
+∞
6.8
7
*
Y78
ICPC
Malign neopl male genital other
+∞
6.8
7
*
Y77
ICD-10 Finland
Ophthalmic devices associated with adverse incidents
+∞
6.8
7
*
C67.0
ICD-10 Finland
Malignant neoplasm: Trigone of bladder
+∞
6.8
7
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
6.8
7
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
6.8
7
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
6.8
205
1138
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
2.9
6.8
39
112
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
6.8
142
716
A50
ICPC
General and Unspecified, Medication/prescr/renewal
1.9
6.7
87
376
R32
ICD-10 Finland
Unspecified urinary incontinence
3.2
6.7
33
86
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.3
6.7
15
395
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.4
6.7
56
200
N30.0
ICD-10 Finland
Acute cystitis
1.7
6.6
121
588
A10AA01
ATC
NA
0.3
6.6
17
422
KH1AD
NOMESCO Finland
CT of urinary organs
1.7
6.6
129
637
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
6.6
1251
9124
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
0.4
6.6
24
516
U13
ICPC
Bladder symptom/complaint other
2.7
6.6
43
134
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.8
6.6
117
564
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
3.1
6.6
34
92
N05AH02
ATC
clozapine; systemic
0.3
6.5
11
334
N41.0
ICD-10 Finland
Acute prostatitis
1.7
6.5
116
560
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
13.1
6.5
11
7
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
3.2
6.5
32
84
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.3
1388
10259
UJF32
NOMESCO Finland
Coloscopy
1.3
6.3
637
4334
J01CA08
ATC
pivmecillinam; oral
1.8
6.2
106
502
WX872
NOMESCO Finland
Intensive care
0.6
6.2
87
1210
G04BE08
ATC
tadalafil; oral
8.4
6.2
13
13
N13.8
ICD-10 Finland
Other obstructive and reflux uropathy
18.8
6.1
9
*
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
2.9
6.0
35
102

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_PROSTATE_EXALLC – Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

GWS hits: 116

This endpoint is excluded (different definition than used in FinnGen).