Dental caries 1 and operation codes, only avohilmo

K11_CARIES_1_OPER_ONLYAVO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • K11_DENTAL_OPER_ONLYAVO
278821

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

213196

6. Filter based on genotype QC (FinnGen only)

213196

Control definitions (FinnGen only)

Control conditions
K11_DENTAL_OPER

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1978827 1055614 913650
Only index persons 1873922 1009115 864807
Unadjusted period prevalence (%)
Whole population 27.96 30.24 25.53
Only index persons 35.21 37.10 33.01
Median age at first event (years)
Whole population 35.88 36.96 34.67
Only index persons 37.70 38.55 36.71

-FinnGen-

Key figures

All Female Male
Number of individuals 213196 133605 79591
Unadjusted period prevalence (%) 41.64 45.54 35.09
Median age at first event (years) 50.61 47.82 55.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
186
2441
0.38
39.46
4.2
4.1
—
—
—
0
0
12673
59990
1.35
39.10
4.9
4.7
2.0
2.2
mu/l
0.53
11770
55997
138
1997
0.34
36.23
2.9
3.4
7.1
7.4
mmol/l
1.21
133
1965
13645
65615
1.40
34.43
15.8
16.6
4.0
4.0
mmol/l
1.08
13313
64004
13613
65448
1.40
34.16
15.6
16.5
139.6
139.6
mmol/l
0.49
13306
63941
160
2073
0.38
32.95
2.7
3.4
1.5
1.5
mmol/l
0.00
153
2037
12785
61041
1.31
31.01
4.5
4.3
5.9
5.8
mmol/l
9.13
11773
56753
11938
56665
1.26
28.17
5.6
5.4
39.3
38.8
mmol/mol
6.26
11132
53207
14970
73772
1.77
26.23
20.8
21.0
255.2
253.2
e9/l
3.31
14652
72173
14980
73836
1.78
26.22
20.8
21.0
4.5
4.5
e12/l
12.63
14628
72063
14979
73830
1.78
26.21
20.7
20.9
90.5
90.6
fl
0.59
14827
73000
14984
73864
1.79
26.15
20.9
21.2
135.5
134.8
g/l
8.02
14832
73042
14978
73832
1.77
25.97
20.7
20.9
30.2
30.2
pg
2.47
14826
73004
14981
73863
1.77
25.64
20.8
21.1
6.7
6.7
e9/l
3.00
14625
72092
73
1216
0.30
25.46
2.4
2.5
—
—
—
0
0
14209
69273
1.41
25.20
10.4
10.7
26.0
26.1
u/l
0.18
13773
67229
471
3879
0.60
24.84
3.4
4.2
25.3
25.4
mmol/l
0.25
450
3774
10364
48690
1.21
24.44
7.3
8.2
77.7
78.3
u/l
0.56
9749
46217
3660
15575
1.24
23.62
1.7
1.7
1.4
1.3
mmol/l
3.40
3113
13556
13138
63460
1.28
22.67
4.7
4.6
2.8
2.8
mmol/l
0.34
12216
59447
10869
51543
1.20
21.28
4.1
4.0
14.7
14.7
pmol/l
0.41
9945
47346
433
3483
0.61
20.66
6.2
5.3
1.6
1.6
%
0.39
406
3276
3815
16500
1.22
20.53
3.1
3.3
—
—
—
0
0
6131
27743
1.18
20.02
6.0
7.7
1.2
1.2
mmol/l
1.11
5586
25372
433
3451
0.62
19.85
6.2
5.4
0.9
0.9
%
0.35
409
3244
13617
66262
1.29
19.72
13.9
14.5
21.8
22.7
mg/l
2.27
10882
51941
638
4673
0.67
19.54
3.6
4.5
128.8
127.9
g/l
0.42
621
4562
3453
14871
1.22
19.16
4.0
4.8
91.4
91.6
%
0.15
3355
14515
12942
62664
1.24
18.72
4.3
4.2
4.6
4.7
mmol/l
5.56
12135
58965
12838
62125
1.23
18.46
4.3
4.1
1.4
1.5
mmol/l
21.88
11958
58256
14111
69086
1.33
18.27
12.9
13.7
—
—
—
0
0
1323
5138
1.32
17.40
3.8
4.1
—
—
—
0
0
4238
18760
1.19
17.14
3.5
3.4
7.7
7.5
mmol/l
1.68
3615
16135
430
1356
1.61
16.91
2.1
2.1
—
—
—
0
0
3655
16046
1.19
16.04
6.6
7.6
—
—
—
0
0
3861
17070
1.18
15.53
3.1
3.4
0.4
0.3
e6/l
0.28
2914
13161
1376
5472
1.29
15.16
2.5
2.7
34.5
44.1
u/l
0.84
1154
4753
4910
22184
1.17
15.00
3.8
3.9
97.9
78.3
e6/l
0.73
3428
15763
10230
48801
1.16
14.80
4.2
4.2
11.2
11.4
mm/h
0.92
9535
45721
3667
16202
1.18
14.72
2.2
2.3
2.8
2.9
mg/l
2.25
3148
14067
12378
59972
1.19
14.69
3.8
3.8
1.3
1.2
mmol/l
7.20
11466
55980
4172
18668
1.17
14.26
3.3
3.5
77.8
61.5
e6/l
0.39
3210
14525
4057
18115
1.17
14.24
3.9
5.1
7.4
7.4
ph
0.88
805
3326
9164
43424
1.15
14.18
4.6
4.5
540.0
1749.6
e6/l
2.69
110
558
6268
28972
1.15
13.65
9.6
10.0
0.0
0.0
e9/l
2.15
5120
24258
2975
13005
1.19
13.34
2.5
2.8
6.2
5.5
e6/l
1.52
2585
11503
1956
8224
1.22
13.25
1.2
1.2
—
—
—
0
0
9070
43085
1.14
12.82
3.7
3.7
—
—
—
0
0
3699
16508
1.17
12.82
3.5
3.4
325.9
598.9
mg/l
3.01
2375
10419
5579
25676
1.14
12.61
2.1
2.1
—
—
—
0
0
9612
45872
1.14
12.50
4.4
4.5
—
—
—
0
0
4914
22527
1.14
11.47
6.0
6.9
—
—
—
0
0
3622
16256
1.16
11.43
1.3
1.3
1.8
1.8
u/ml
0.14
957
4328
752
2862
1.34
11.36
1.9
1.8
—
—
—
0
0
246
1948
0.63
11.07
3.8
3.5
23.4
24.4
mg/l
0.18
130
1294
1660
7002
1.21
10.79
24.6
24.4
1.3
1.3
inr
0.19
233
1083
491
3369
0.72
10.35
3.2
3.8
0.6
0.7
%
3.58
469
3267
1654
7003
1.21
10.34
4.5
4.2
32.2
32.7
%
0.90
1218
4961
2445
10774
1.17
9.63
1.3
1.3
10.2
10.4
u/ml
0.05
908
4266
399
1407
1.44
9.56
3.0
2.5
—
—
—
0
0
2345
10312
1.17
9.47
2.8
3.0
2.4
2.4
mmol/l
0.14
2064
9127
1998
8690
1.18
9.22
3.1
2.8
0.7
0.7
ug/l
0.67
1324
5602
276
910
1.53
9.20
5.6
5.0
368.0
377.1
umol/l
0.46
239
779
6519
30714
1.12
9.04
2.9
3.0
103.3
119.5
ug/l
6.67
6041
28899
127
341
1.88
8.93
12.7
10.4
0.6
0.6
mmol/l
0.33
116
302
1764
7612
1.19
8.92
1.3
1.3
—
—
—
0
0
7882
37546
1.11
8.87
4.8
5.4
6.6
6.6
mmol/l
1.09
7339
34686
5347
24934
1.12
8.85
2.0
1.9
95.7
97.6
pmol/l
1.96
2841
13135
3845
17585
1.13
8.81
4.2
4.1
8.4
11.8
mg/mmol
3.38
2406
11436
470
1735
1.37
8.71
1.4
1.3
—
—
—
0
0
941
5794
0.80
8.68
3.5
5.1
4.8
4.7
kpa
1.13
907
5655
3102
14019
1.14
8.51
1.5
1.5
20.2
20.8
nmol/l
1.23
2685
12229
338
1188
1.44
8.30
1.3
1.4
—
—
—
0
0
1139
6837
0.82
8.16
4.2
6.0
1.9
1.8
mmol/l
0.43
918
5656
9230
44494
1.11
7.74
3.2
3.2
44.7
45.9
u/l
0.55
8654
42048
2547
11440
1.14
7.57
1.3
1.3
35.6
32.0
iu/ml
0.42
772
3565
3110
14151
1.13
7.57
1.4
1.5
2.4
2.3
g/l
1.10
1853
8978
2212
9846
1.15
7.49
3.0
3.0
2.7
3.1
e6/l
0.66
1168
5694
6673
31686
1.10
7.44
6.3
6.8
2.8
2.8
%
0.43
6202
29841
716
4460
0.80
7.36
7.5
7.9
24.6
24.5
mmol/l
0.11
678
4134
1151
6833
0.83
7.31
4.2
6.0
5.8
5.8
kpa
0.81
1110
6665
5760
27167
1.11
7.31
2.3
2.4
75.8
77.5
nmol/l
4.24
5224
24914
11376
58774
0.90
7.29
18.0
18.1
332.7
333.0
g/l
2.99
11301
58332
2548
11474
1.14
7.27
3.7
3.8
323.0
408.9
ng/l
1.01
1836
8341
6713
31909
1.10
7.27
6.6
7.0
8.4
8.5
%
0.94
6284
30191
4019
18624
1.11
7.09
2.2
2.2
236.8
185.6
u/l
0.93
3783
17557
263
1866
0.70
6.92
8.5
7.4
11.3
11.2
mmol/l
0.16
240
1684
264
1866
0.71
6.80
8.5
7.4
105.7
105.0
mmol/l
1.50
241
1684
625
3909
0.80
6.69
2.9
3.7
—
—
—
0
0
69
663
0.52
6.66
33.3
39.5
8.0
7.4
ug/l
0.85
63
606
1202
7051
0.84
6.65
4.2
6.0
7.4
7.4
ph
—
9
28
6449
30695
1.10
6.54
6.4
6.8
0.7
0.7
%
0.20
6017
28904
6912
33013
1.10
6.48
5.8
7.0
11.2
11.0
umol/l
0.32
6531
31332
7344
35199
1.09
6.31
6.5
6.7
0.2
0.2
e9/l
0.30
6513
31634
591
2365
1.27
6.29
3.2
2.6
—
—
—
0
0
4438
20780
1.10
6.28
3.0
3.6
2.4
2.4
mmol/l
0.27
3916
18470
668
2720
1.25
6.14
2.3
1.9
—
—
—
0
0
389
2549
0.76
6.11
7.0
6.4
1.2
1.3
mmol/l
0.63
342
2279
3341
15438
1.11
6.08
2.2
2.6
—
—
—
0
0
6647
31754
1.09
6.05
6.7
8.6
1.2
1.2
mmol/l
0.39
5602
27302
52
529
0.49
6.05
4.7
4.9
—
—
—
0
0
8095
39042
1.09
5.83
9.1
9.8
4.1
4.0
e9/l
1.74
7078
34915
7106
34097
1.09
5.73
6.2
6.5
0.0
0.0
e9/l
1.82
6166
30300
7078
33959
1.09
5.72
6.2
6.5
0.6
0.6
e9/l
0.21
6147
30186
6894
33042
1.09
5.70
6.4
6.8
28.8
28.7
%
0.06
6424
31140
6799
32573
1.09
5.66
6.1
6.6
56.7
56.6
%
0.12
6363
30784
1339
5867
1.16
5.60
4.1
5.0
—
—
—
0
0
1526
6758
1.15
5.52
1.3
1.3
—
—
—
0
0
78
218
1.80
5.05
2.1
2.0
215.0
86.7
ug/min
0.65
21
48
385
1505
1.29
5.02
2.5
2.6
38.0
37.8
g/l
0.15
341
1283
135
445
1.53
4.73
1.4
1.3
1.4
1.5
nmol/l
0.18
121
403
163
560
1.47
4.70
1.7
1.4
—
—
—
0
0
2348
10790
1.11
4.64
2.8
2.9
1.1
1.1
e6/l
0.09
1302
6616
1588
7141
1.13
4.58
2.7
3.6
7.7
8.3
umol/l
0.48
1357
6255
1150
5065
1.15
4.52
7.3
8.4
1.3
1.3
mmol/l
0.25
1104
4902
52
476
0.55
4.42
1.1
1.1
—
—
—
0
0
775
3320
1.18
4.35
2.3
1.8
—
—
—
0
0
767
4503
0.85
4.35
5.2
5.7
—
—
—
0
0
610
3651
0.83
4.33
3.0
3.0
0.2
0.2
e6/l
0.03
589
3570
297
1918
0.77
4.29
1.3
1.8
112.2
119.7
u/ml
0.52
57
437
54
478
0.57
4.10
1.0
1.0
—
—
—
0
0
835
3620
1.17
4.07
2.2
1.8
—
—
—
0
0
321
2038
0.79
4.06
1.3
1.8
14.0
18.5
u/ml
—
5
43
322
2043
0.79
4.05
1.4
1.8
—
—
—
0
0
832
3609
1.17
4.03
2.2
1.8
—
—
—
0
0
181
1236
0.73
3.95
2.4
2.5
—
—
—
0
0
1372
6173
1.13
3.94
1.4
1.5
—
—
—
0
0
825
3588
1.16
3.88
2.2
1.8
—
—
—
0
0
817
3553
1.16
3.85
2.2
1.8
—
—
—
0
0
67
549
0.61
3.79
23.0
30.5
115.9
124.5
ug/l
0.46
58
454
464
2808
0.83
3.76
1.9
2.2
1.9
2.2
ug/l
0.16
411
2486
3448
16280
1.08
3.75
3.0
3.3
1203.1
1383.8
ng/l
1.20
2901
14006
7272
35279
1.07
3.72
6.2
6.5
2.0
1.9
e9/l
0.88
6458
31780
174
1179
0.74
3.64
1.2
1.2
—
—
—
0
0
468
1949
1.21
3.63
2.5
2.5
—
—
—
0
0
65
192
1.70
3.61
2.7
2.3
155.2
145.4
nmol/l
0.40
59
166
1309
5906
1.12
3.61
1.2
1.2
—
—
—
0
0
388
1593
1.23
3.48
8.3
10.7
—
—
—
0
0
3423
16204
1.08
3.46
2.5
3.1
1914.5
6764.3
umol/l
13.54
2970
14386
3664
17395
1.08
3.43
3.6
4.0
—
—
—
0
0
7
116
0.30
3.40
1.0
1.1
—
—
—
0
0
655
2832
1.17
3.37
10.0
11.0
24.2
24.2
mmol/l
0.07
626
2656
825
3631
1.15
3.35
2.3
2.3
7617.4
6536.9
u/l
0.33
311
1437
2938
15729
0.92
3.34
3.9
4.1
1.0
1.0
kg/l
0.87
402
2384
3731
17754
1.07
3.26
4.0
4.2
0.0
0.0
estimate
0.03
1405
5661
16
195
0.41
3.22
1.9
2.8
—
—
—
0
0
1024
4600
1.13
3.07
3.1
2.5
4.0
4.0
e9/l
0.09
842
3606
1982
9217
1.09
3.07
2.6
2.4
119.5
132.0
ug/g
0.86
1566
7295
11415
56364
1.07
3.07
16.9
17.1
13.6
13.6
%
1.20
11195
55300
375
1557
1.22
3.06
1.9
1.9
4.8
10.2
iu/l
0.46
136
537
961
4312
1.13
2.95
3.1
3.2
4.5
4.5
pmol/l
0.03
854
3890
597
2599
1.16
2.86
1.1
1.1
—
—
—
0
0
688
3028
1.15
2.85
1.1
1.1
2.7
11.4
u/ml
—
9
53
99
702
0.71
2.84
2.8
3.0
532.2
523.7
e6/l
0.06
84
588
60
468
0.64
2.83
1.2
1.2
—
—
—
0
0
96
683
0.70
2.82
2.9
3.0
0.2
0.2
e9/l
0.68
84
586
691
3045
1.15
2.81
1.6
1.6
306.2
309.6
mu/l
0.10
620
2770
771
4373
0.88
2.81
1.4
1.4
—
—
—
0
0
14
24
2.93
2.77
4.1
1.9
—
—
—
0
0
97
686
0.71
2.76
1.9
1.9
2.1
2.4
u/field
0.25
57
226
61
470
0.65
2.73
1.6
2.1
—
—
—
0
0
110
394
1.41
2.72
2.2
2.5
—
—
—
0
0
42
350
0.60
2.67
2.4
2.9
317.5
200.1
e6/l
0.74
24
201
401
2372
0.85
2.63
4.8
7.6
1.4
1.4
mg/l
0.69
378
2246
2670
12649
1.07
2.61
2.7
3.0
550.0
552.4
mosm/kgh2o
0.19
2264
10893
3022
14379
1.07
2.61
1.8
2.0
1.2
1.2
mg/l
0.61
2215
11007
145
548
1.33
2.60
2.7
2.9
—
—
—
0
0
167
1080
0.77
2.60
1.5
1.8
—
—
—
0
0
167
1080
0.77
2.60
1.5
1.8
—
—
—
0
0
167
1080
0.77
2.60
1.5
1.8
—
—
—
0
0
167
1080
0.77
2.60
1.5
1.8
—
—
—
0
0
4571
22039
1.06
2.60
3.2
3.8
35.3
31.9
u/l
0.47
4345
21045
93
327
1.43
2.57
1.4
1.4
5.8
5.4
mmol/l
0.73
87
307
2383
11252
1.08
2.55
1.8
1.7
1155.8
1173.9
nmol/l
0.42
1846
8855
3402
16273
1.07
2.50
4.9
4.8
2.8
3.1
ug/l
0.28
3052
14825
4431
23188
0.94
2.47
2.7
2.6
—
—
—
0
0
2770
13166
1.07
2.46
1.7
1.6
16580962.8
43178399.1
pmol/l
2.25
2322
11177
58
440
0.66
2.45
2.3
3.6
—
—
—
0
0
1708
7980
1.09
2.40
1.5
1.6
—
—
—
0
0
141
921
0.77
2.40
2.6
2.8
1.3
1.1
e9/l
1.51
87
579
727
3253
1.13
2.40
4.5
7.8
24.2
23.9
mmol/l
1.48
665
2999
892
4040
1.12
2.39
7.8
10.4
24.9
24.7
mmol/l
0.56
886
4003
1319
7199
0.91
2.39
1.3
1.3
—
—
—
0
0
69
233
1.49
2.36
1.7
2.3
—
—
—
0
0
6
5
6.03
2.35
2.0
2.0
—
—
—
0
0
6
5
6.03
2.35
1.0
1.0
—
—
—
0
0
554
2444
1.14
2.29
1.6
1.7
—
—
—
0
0
18
40
2.26
2.27
10.7
5.6
—
—
—
0
0
80
281
1.43
2.26
2.4
2.5
52.1
56.3
umol/l
0.58
64
230
237
974
1.23
2.24
1.5
1.5
—
—
—
0
0
374
1608
1.17
2.19
3.7
4.5
7.4
7.4
ph
0.33
322
1375
115
434
1.33
2.15
1.7
1.7
6.5
6.3
mmol/l
0.27
80
314
1483
8014
0.92
2.15
7.2
7.7
104.2
104.5
mmol/l
1.33
1454
7865
1091
5026
1.10
2.14
1.2
1.2
141.4
137.6
iu/ml
0.11
392
1943
197
799
1.24
2.12
1.3
1.2
—
—
—
0
0
42
329
0.64
2.11
1.2
1.3
—
—
—
0
0
1119
6115
0.91
2.11
8.8
8.8
121.8
119.9
g/l
2.17
1086
5858
661
3709
0.89
2.10
11.1
10.3
—
—
—
0
0
330
1410
1.18
2.10
1.1
1.1
—
—
—
0
0
229
1390
0.83
2.08
1.3
1.2
3.4
3.6
ug/l
0.33
207
1264
163
1023
0.80
2.05
3.8
4.1
31.7
40.6
u/ml
0.63
156
985
982
4515
1.10
2.02
1.3
1.2
—
—
—
0
0
21
193
0.55
2.00
1.4
1.3
—
—
—
0
0
2686
12841
1.06
2.00
4.3
4.3
21.6
22.0
%
0.85
1227
6064
30
86
1.75
1.98
1.8
1.7
—
—
—
0
0
2009
9521
1.07
1.96
1.4
1.4
479.6
549.0
titre
0.97
419
1906
48
157
1.54
1.95
1.4
1.4
—
—
—
0
0
176
1087
0.81
1.93
6.8
7.1
12.0
11.3
mg/l
1.26
162
1007
8
97
0.41
1.92
5.3
5.0
—
—
—
0
0
407
1783
1.15
1.91
3.2
3.2
—
—
—
0
0
6
7
4.31
1.91
1.2
1.0
66.1
66.7
%
—
6
7
24
65
1.86
1.89
9.3
10.8
—
—
—
0
0
327
1411
1.17
1.88
3.9
4.5
2.5
2.5
mmol/l
0.02
217
916
118
760
0.78
1.88
1.5
1.4
31.6
32.3
g/l
0.25
106
700
104
396
1.32
1.87
1.2
1.1
2.7
6.6
nmol/l
0.73
18
68
327
1412
1.17
1.87
3.9
4.5
5.0
5.0
kpa
0.10
322
1375
4088
19808
1.05
1.86
3.0
3.0
—
—
—
0
0
394
1726
1.15
1.86
1.2
1.2
—
—
—
0
0
90
336
1.35
1.85
1.8
1.7
1.8
2.6
u/field
0.54
67
252
328
1418
1.17
1.85
3.9
4.5
8.6
8.8
kpa
0.83
322
1381
89
593
0.75
1.84
1.2
1.2
—
—
—
0
0
88
587
0.75
1.83
1.2
1.1
381.0
376.5
nmol/l
0.08
78
495
71
256
1.40
1.81
3.5
3.1
158.7
119.2
au/ml
—
10
32
94
355
1.33
1.80
1.9
2.0
—
—
—
0
0
44
328
0.67
1.79
2.3
2.6
71.5
69.3
ug/l
0.05
44
318
5182
25273
1.05
1.79
8.7
9.2
1.2
1.2
inr
0.03
1588
7020
258
1097
1.19
1.79
1.6
1.5
—
—
—
0
0
346
1997
0.87
1.76
4.1
5.0
3.9
3.9
mmol/l
0.62
323
1899
1217
6569
0.93
1.75
8.4
8.5
96.1
96.1
%
0.08
1184
6272
12
25
2.41
1.75
1.5
1.4
10.0
19.7
nmol/l
0.68
12
25
21
56
1.89
1.75
1.1
1.2
—
—
—
0
0
3315
16003
1.05
1.75
2.0
2.0
—
—
—
0
0
18
165
0.55
1.74
1.5
1.4
—
—
—
0
0
289
1246
1.17
1.71
2.4
2.5
110.1
146.6
ug/min
0.59
180
735
464
2072
1.13
1.68
1.1
1.2
—
—
—
0
0
903
4178
1.09
1.67
1.3
1.3
52.9
46.6
au/ml
0.22
28
173
122
484
1.27
1.66
1.1
1.1
7.6
7.8
iu/ml
0.05
27
128
246
1050
1.18
1.66
1.1
1.1
99.2
1492.3
iu/ml
0.82
67
231
214
1274
0.84
1.64
1.2
1.2
—
—
—
0
0
146
593
1.24
1.63
4.3
4.0
86.3
138.5
u/ml
0.47
43
164
369
2107
0.88
1.63
3.6
3.3
439.3
4417.8
u/ml
0.75
303
1800
117
737
0.80
1.60
2.2
2.5
11.1
14.1
%
1.74
50
418
4739
23124
1.04
1.57
3.5
3.6
32.7
76.2
ng/l
1.21
3053
14902
5619
27520
1.04
1.56
4.9
5.8
36.0
35.8
g/l
2.29
5247
25717
11
113
0.49
1.55
1.5
1.2
—
—
—
0
0
104
409
1.28
1.54
1.6
1.6
6.1
5.8
u/l
0.16
94
353
404
1802
1.13
1.52
1.3
1.3
1316.3
1176.0
titre
0.12
16
45
257
1113
1.16
1.48
1.5
1.4
—
—
—
0
0
471
2125
1.12
1.47
2.6
2.8
3.8
3.7
g/l
0.65
353
1391
1096
5894
0.93
1.47
3.7
4.0
18.1
18.9
ug/l
0.04
878
4692
72
271
1.34
1.47
2.6
2.4
10.0
9.2
mmol/l
0.55
60
183
206
878
1.18
1.45
1.2
1.4
44.4
40.8
u/l
0.09
174
773
466
2598
0.90
1.42
4.7
5.6
—
—
—
0
0
853
3971
1.08
1.41
2.4
2.8
—
—
—
0
0
213
1249
0.86
1.41
1.2
1.2
—
—
—
0
0
223
960
1.17
1.40
3.2
3.2
0.8
0.8
nmol/l
2.13
172
729
55
201
1.38
1.36
2.4
2.3
—
—
—
0
0
1479
7034
1.06
1.36
2.8
3.2
1.7
1.8
%
2.05
1305
6308
1150
6153
0.93
1.35
7.7
11.6
8.6
9.5
mmol/l
4.58
1102
5909
52
355
0.74
1.35
3.5
8.6
72.1
2119.7
mg/l
1.35
38
280
100
626
0.80
1.34
1.2
1.2
—
—
—
0
0
108
670
0.81
1.34
2.5
2.9
647.2
656.6
e6/l
0.05
43
246
25
194
0.65
1.31
1.6
1.7
—
—
—
0
0
1624
7757
1.06
1.30
1.8
1.8
—
—
—
0
0
969
4552
1.07
1.29
2.4
2.4
20.6
22.4
au/ml
0.19
47
269
1379
6556
1.06
1.29
2.1
2.4
360.5
379.2
nmol/l
2.97
1274
6085
85
538
0.79
1.27
2.6
2.9
47.0
36.4
%
3.60
25
224
13
33
1.98
1.27
1.5
1.3
381.4
271.4
umol/24h
1.06
13
33
44
157
1.41
1.27
1.1
1.2
—
—
—
0
0
25
192
0.65
1.26
1.2
1.2
—
224.0
—
0
5
183
785
1.17
1.24
1.3
1.3
—
—
—
0
0
38
268
0.71
1.23
1.4
1.8
—
—
—
0
0
109
446
1.23
1.22
1.2
1.2
—
—
—
0
0
11
103
0.54
1.21
7.2
3.6
1.2
6.9
%
—
5
37
4249
20789
1.04
1.20
2.3
2.6
—
—
—
0
0
23
72
1.61
1.20
1.0
1.0
—
—
—
0
0
101
621
0.82
1.18
1.2
1.2
335.8
200.0
titre
0.56
19
102
50
335
0.75
1.18
1.3
1.3
—
—
—
0
0
1359
7195
0.94
1.17
8.0
8.1
1.0
1.2
mmol/l
1.01
1086
5598
5
9
2.79
1.17
2.0
3.1
—
—
—
0
0
344
1923
0.90
1.15
4.6
6.5
8.9
8.9
kpa
0.02
322
1802
222
974
1.15
1.15
1.0
1.1
0.5
0.5
u/ml
0.07
52
209
192
834
1.16
1.14
1.2
1.3
—
—
—
0
0
1022
4837
1.07
1.13
1.3
1.3
220.1
209.1
u/ml
0.13
941
4507
29
98
1.49
1.12
1.8
2.1
6.8
6.9
mmol/l
0.11
19
61
29
210
0.69
1.11
1.1
1.2
12.2
10.5
u/ml
0.05
24
150
49
183
1.35
1.11
1.2
1.2
15.3
27.6
%
—
6
38
115
479
1.21
1.11
1.3
1.8
—
—
—
0
0
3106
16102
0.96
1.11
4.6
4.7
—
—
—
0
0
47
175
1.35
1.09
1.5
1.3
—
—
—
0
0
76
303
1.26
1.09
4.2
2.7
—
—
—
0
0
2718
13212
1.04
1.08
1.7
1.8
—
—
—
0
0
87
537
0.81
1.08
1.4
1.3
6.0
6.2
mmol/l
0.22
81
503
29
99
1.47
1.07
1.4
1.6
—
—
—
0
0
9
22
2.06
1.07
1.0
1.0
—
—
—
0
0
162
699
1.17
1.06
1.5
1.9
—
—
—
0
0
114
684
0.84
1.06
1.4
1.5
1896.8
2836.1
e6/l
0.94
80
522
130
551
1.19
1.05
1.6
1.4
1.4
1.3
promille
0.16
95
427
5
10
2.51
1.05
1.2
1.0
2.0
2.0
mmol/24h
—
5
10
29
207
0.70
1.04
1.5
1.4
64.2
61.7
%
0.14
24
178
3443
16825
1.04
1.04
4.2
4.6
—
—
—
0
0
1077
5122
1.06
1.04
3.8
4.5
1.2
1.2
mmol/l
0.38
930
4575
89
364
1.23
1.04
1.1
1.2
7.5
19.6
u/ml
0.43
11
32
71
283
1.26
1.03
1.6
1.5
7.6
6.1
mmol/24h
—
6
21
233
1035
1.13
1.03
1.2
1.2
—
—
—
0
0
0
17
0.00
1.02
0.0
1.0
—
0.2
—
0
9
43
160
1.35
1.02
2.2
1.9
17.6
17.2
umol/l
0.09
43
160
404
1853
1.10
1.01
1.3
1.3
80.3
98.3
titre
0.63
29
183
84
516
0.82
1.01
1.4
1.4
31.4
33.2
nmol/l
0.23
74
484
1246
5958
1.06
1.01
1.4
1.5
—
—
—
0
0
203
896
1.14
1.00
3.3
3.5
64.6
393.9
u/ml
0.85
191
853
23
76
1.52
1.00
1.8
2.9
—
—
—
0
0
72
448
0.81
0.99
2.0
1.4
—
—
—
0
0
16
127
0.63
0.98
1.1
1.2
2.4
1.6
mmol/l
—
10
80
155
672
1.16
0.98
1.7
2.3
—
—
—
0
0
787
3715
1.07
0.98
1.2
1.1
70.7
210.9
titre
1.53
21
106
72
290
1.25
0.98
4.4
3.5
8.0
8.7
mg/l
0.40
61
233
46
301
0.77
0.96
1.1
1.0
—
—
—
0
0
554
2997
0.93
0.96
1.5
1.6
24.6
15.0
u/ml
0.29
13
93
198
1127
0.88
0.95
2.9
3.4
—
—
—
0
0
1088
5196
1.06
0.93
4.4
4.4
0.2
0.1
%
0.28
260
1321
2149
10432
1.04
0.93
2.5
3.0
13.3
13.3
umol/l
0.07
1976
9712
10
88
0.57
0.93
1.1
1.4
—
242.8
—
0
8
341
1880
0.91
0.93
1.3
1.6
9.9
15.4
iu/ml
—
9
49
46
299
0.77
0.92
1.7
1.4
—
—
—
0
0
892
4238
1.06
0.92
1.8
2.0
1.4
1.3
g/l
0.60
818
3889
224
1262
0.89
0.92
3.5
3.6
1.7
1.6
%
0.10
179
962
133
775
0.86
0.91
2.2
2.5
42.9
39.1
%
0.37
15
96
546
2553
1.08
0.90
1.1
1.1
—
—
—
0
0
84
348
1.21
0.90
1.0
1.0
686.1
717.4
ng/l
0.22
55
234
62
387
0.80
0.90
1.1
1.1
1614.2
1611.2
miu/ml
0.01
62
387
41
269
0.77
0.89
8.3
7.2
25.2
25.1
mmol/l
0.06
41
241
137
594
1.16
0.89
1.1
1.2
—
—
—
0
0
6
59
0.51
0.88
4.8
3.1
—
—
—
0
0
141
815
0.87
0.87
1.5
1.4
6.3
6.8
g/l
1.08
94
581
61
245
1.25
0.87
1.9
2.3
—
—
—
0
0
109
465
1.18
0.87
1.2
1.1
1.0
1.1
ratio
2.00
43
157
141
814
0.87
0.86
1.5
1.4
0.4
0.4
g/l
0.73
91
588
141
814
0.87
0.86
1.5
1.4
3.1
2.8
g/l
1.07
93
587
123
717
0.86
0.86
5.7
4.9
7.5
7.2
mmol/l
0.30
102
584
693
3700
0.94
0.85
1.7
1.6
—
—
—
0
0
39
148
1.33
0.85
1.1
1.1
—
—
—
0
0
0
13
0.00
0.84
0.0
1.0
—
—
—
0
0
605
3242
0.94
0.84
1.4
1.4
—
—
—
0
0
1123
5388
1.05
0.83
8.5
10.7
—
—
—
0
0
1367
7160
0.96
0.83
8.0
8.1
5.1
5.0
kpa
2.46
1316
6812
51
322
0.80
0.83
7.4
12.4
—
—
—
0
0
222
1242
0.90
0.83
1.8
1.6
0.8
0.7
g/l
0.39
162
941
1367
7159
0.96
0.83
7.9
8.1
12.6
12.8
kpa
0.33
1319
6812
198
887
1.12
0.82
1.3
1.3
0.3
0.1
nmol/l
0.72
11
53
158
698
1.14
0.81
1.5
1.5
21.6
37.2
iu/ml
—
10
33
434
2022
1.08
0.81
2.6
2.8
10.1
10.0
g/l
0.23
371
1641
78
325
1.21
0.81
1.5
1.2
141.7
136.2
nmol/l
0.42
78
325
69
284
1.22
0.81
2.8
3.5
1.2
1.5
ug/l
0.46
63
272
2199
10716
1.04
0.80
3.4
4.8
0.8
0.8
mmol/l
0.26
2065
10114
95
404
1.18
0.80
1.6
1.5
9.5
7.3
ug/l
0.51
79
363
237
1317
0.90
0.79
2.0
2.1
4.0
5.9
titre
—
7
23
352
1920
0.92
0.79
1.2
1.5
238.9
256.2
u/ml
0.60
207
1250
19
64
1.49
0.79
1.0
1.1
—
—
—
0
0
124
540
1.16
0.79
1.2
1.2
66.6
42.1
u/ml
—
5
26
1114
5355
1.05
0.78
3.9
4.1
0.7
0.7
%
0.08
242
1223
75
451
0.84
0.78
1.4
1.8
2023.6
2020.1
ml
0.00
12
144
142
811
0.88
0.77
1.5
1.4
—
—
—
0
0
7
18
1.96
0.77
1.1
1.0
—
—
—
0
0
269
1232
1.10
0.76
2.3
2.5
8.1
7.5
umol/l
0.10
193
942
26
177
0.74
0.76
2.0
2.6
—
—
—
0
0
372
1730
1.08
0.75
1.5
1.7
516.6
512.9
mg/l
0.04
350
1659
1906
9278
1.04
0.75
1.8
1.7
—
—
—
0
0
362
1682
1.08
0.75
1.4
1.4
—
—
—
0
0
304
1402
1.09
0.74
3.3
4.2
—
—
—
0
0
46
183
1.26
0.74
1.2
1.3
125.9
113.8
nmol/l
0.17
35
140
5
12
2.09
0.74
1.0
1.0
—
—
—
0
0
5
12
2.09
0.74
1.2
1.5
—
—
—
0
0
168
752
1.12
0.73
2.3
2.9
20.1
21.2
nmol/l
0.58
157
715
1944
9472
1.04
0.73
1.6
1.8
—
—
—
0
0
82
348
1.19
0.73
1.5
1.3
75.4
53.1
%
1.75
17
42
390
1820
1.08
0.73
1.3
1.3
10.2
9.4
u/ml
0.07
72
251
82
349
1.18
0.71
1.0
1.0
303.5
336.8
ng/l
0.47
53
249
69
289
1.20
0.71
2.4
2.2
21.5
656.1
ug/l
1.08
61
269
20
70
1.44
0.71
1.2
1.8
—
—
—
0
0
4262
21026
1.03
0.71
2.6
2.7
56.2
58.3
u/l
1.75
3935
19550
225
1027
1.10
0.70
1.1
1.1
117.4
115.5
%
0.41
203
947
18
62
1.46
0.69
1.0
1.0
—
—
—
0
0
5
13
1.93
0.69
1.2
1.5
—
—
—
0
0
203
1126
0.90
0.69
1.5
1.9
—
—
—
0
0
31
202
0.77
0.69
8.2
9.5
—
—
—
0
0
21
145
0.73
0.68
10.2
8.3
—
—
—
0
0
70
295
1.19
0.68
2.6
2.3
1973.8
1862.7
ml
0.41
63
268
115
659
0.88
0.68
2.8
2.8
29.9
46.3
mg/l
0.57
88
457
101
584
0.87
0.68
1.1
1.2
—
—
—
0
0
91
530
0.86
0.68
1.5
1.3
74.5
124.0
pmol/l
0.39
30
162
6742
33462
1.02
0.67
3.6
3.8
0.0
0.0
estimate
0.50
1406
5760
235
1292
0.91
0.67
1.4
1.4
21.8
24.6
u/l
0.73
194
1071
60
250
1.21
0.66
1.1
1.1
—
—
—
0
0
402
1887
1.07
0.66
1.5
1.4
297.5
278.9
ug/g
0.91
220
1082
14
46
1.53
0.66
1.1
1.2
—
—
—
0
0
331
1544
1.08
0.65
1.4
1.6
3.7
3.7
mmol/l
0.16
315
1464
130
736
0.89
0.65
2.0
2.0
—
0.8
—
0
6
5
14
1.80
0.64
1.0
1.0
—
—
—
0
0
5
14
1.80
0.64
1.2
1.3
—
—
—
0
0
158
712
1.12
0.64
1.6
1.7
283.5
281.1
mosm/kgh2o
0.58
118
572
0
11
0.00
0.64
0.0
1.1
—
—
—
0
0
239
1309
0.92
0.64
1.5
1.5
0.3
0.4
nmol/l
0.75
188
1059
197
899
1.10
0.63
1.3
1.3
0.7
2.2
nmol/l
0.69
187
866
1951
9538
1.03
0.62
2.5
3.0
2.4
2.3
g/l
0.98
1792
8897
30
193
0.78
0.62
2.4
2.2
556.3
1045.5
e6/l
0.80
24
145
6817
33864
1.02
0.62
3.6
3.9
0.0
0.0
estimate
0.25
1395
5768
61
257
1.19
0.61
1.0
1.0
6.3
11.9
u/ml
—
6
33
7
58
0.61
0.61
1.0
1.2
—
—
—
0
0
14
47
1.50
0.61
1.2
2.2
34.4
52.3
umol/l
2.00
14
47
81
471
0.86
0.61
1.0
1.0
—
—
—
0
0
26
170
0.77
0.61
2.3
2.2
5448.4
14643.8
e6/l
0.78
16
102
31
121
1.29
0.60
1.0
1.2
—
—
—
0
0
96
421
1.15
0.60
1.5
1.4
69.9
69.1
umol/l
—
7
39
11
83
0.67
0.59
1.5
1.3
4.4
9.3
%
—
5
43
269
1459
0.93
0.58
2.7
3.3
35.6
33.5
umol/l
0.26
235
1250
33
208
0.80
0.58
1.8
2.2
—
—
—
0
0
380
1791
1.07
0.58
1.3
1.3
3.5
6.8
u/ml
1.04
46
167
47
285
0.83
0.58
1.4
1.2
—
—
—
0
0
249
1354
0.92
0.58
1.6
1.9
—
—
—
0
0
1082
5243
1.04
0.58
2.4
2.4
7.5
7.4
ug/l
0.08
964
4584
1268
6164
1.04
0.58
2.3
2.7
0.2
0.2
g/l
1.15
1184
5809
8
64
0.63
0.57
1.0
1.1
—
—
—
0
0
8
64
0.63
0.57
1.0
1.1
—
—
—
0
0
62
366
0.85
0.57
2.0
3.1
7.4
7.4
ph
0.55
19
111
44
268
0.82
0.57
1.1
1.2
—
—
—
0
0
77
334
1.16
0.57
1.5
1.5
1.4
1.2
nmol/l
0.40
62
255
107
606
0.89
0.56
1.4
1.4
95984.0
73913.1
e6/l
0.13
60
378
95
541
0.88
0.55
1.6
1.5
—
—
—
0
0
256
1193
1.08
0.55
1.1
1.1
—
—
—
0
0
321
1509
1.07
0.54
1.5
1.8
26.0
36.2
e6/l
0.33
246
1220
90
514
0.88
0.54
1.4
1.5
—
—
—
0
0
221
1203
0.92
0.54
1.2
1.2
—
—
—
0
0
561
2960
0.95
0.53
1.7
1.9
1.5
1.5
g/l
0.21
486
2545
50
298
0.84
0.53
1.2
1.2
—
—
—
0
0
18
66
1.37
0.53
1.1
1.3
—
—
—
0
0
251
1171
1.08
0.53
1.1
1.1
—
—
—
0
0
683
3286
1.05
0.53
4.1
5.8
—
—
—
0
0
33
133
1.25
0.52
1.2
1.2
223.0
440.6
pmol/l
1.12
25
99
81
356
1.14
0.52
6.6
5.9
—
—
—
0
0
466
2468
0.95
0.52
1.5
1.4
—
—
—
0
0
321
1513
1.07
0.51
1.5
1.8
2484.9
1515.1
e6/l
0.38
259
1282
34
138
1.24
0.51
1.4
1.5
—
—
—
0
0
142
647
1.10
0.51
1.4
1.4
12.5
10.6
mmol/l
1.36
37
106
13
45
1.45
0.51
1.5
1.0
—
—
—
0
0
415
1974
1.06
0.50
1.3
1.3
56.1
29.4
u/ml
0.71
23
102
25
159
0.79
0.50
2.0
2.1
—
—
—
0
0
333
1574
1.06
0.50
1.6
1.7
11331.0
12645.9
e6/l
0.23
228
1192
17
114
0.75
0.50
2.8
4.3
—
—
—
0
0
200
928
1.08
0.49
1.4
1.3
7.1
6.9
mmol/l
0.29
134
657
4080
20208
1.02
0.49
1.6
1.5
—
—
—
0
0
984
4781
1.04
0.49
2.3
2.2
12.1
11.7
nmol/l
0.61
872
4288
10
73
0.69
0.48
1.0
1.1
—
—
—
0
0
7
24
1.47
0.47
1.6
1.0
—
—
—
0
0
21
81
1.30
0.47
2.3
2.1
0.8
0.6
u/field
0.45
21
81
62
270
1.15
0.46
1.1
1.1
—
—
—
0
0
222
1039
1.08
0.46
1.5
1.6
—
—
—
0
0
118
654
0.91
0.46
1.6
1.6
33.4
31.7
%
0.20
74
409
112
508
1.11
0.46
1.0
1.1
297.0
284.2
mg/l
0.80
100
451
227
1223
0.93
0.45
1.1
1.1
—
—
—
0
0
227
1222
0.93
0.45
1.1
1.1
—
—
—
0
0
0
8
0.00
0.43
0.0
1.8
—
—
—
0
0
561
2704
1.04
0.43
1.2
1.2
—
—
—
0
0
32
194
0.83
0.43
1.6
1.3
17.4
17.1
umol/l
0.11
26
170
0
9
0.00
0.43
0.0
4.0
—
139.4
—
0
9
10
34
1.48
0.43
2.2
1.9
—
—
—
0
0
18
69
1.31
0.42
1.1
1.3
—
—
—
0
0
263
1243
1.06
0.42
1.1
1.1
6.1
11.2
au/ml
1.22
16
62
169
917
0.93
0.42
1.6
1.6
—
—
—
0
0
1137
5558
1.03
0.42
4.3
4.4
0.1
0.1
%
0.60
301
1599
7
52
0.68
0.41
1.4
1.7
—
—
—
0
0
142
656
1.09
0.41
1.6
1.5
—
—
—
0
0
0
10
0.00
0.41
0.0
6.5
—
—
—
0
0
301
1430
1.06
0.41
1.6
1.8
—
—
—
0
0
277
1313
1.06
0.41
3.9
5.8
—
—
—
0
0
172
931
0.93
0.41
1.3
1.3
58.6
56.1
u/ml
0.04
12
56
978
4772
1.03
0.41
1.4
1.4
—
—
—
0
0
378
1995
0.95
0.41
1.5
1.5
—
—
—
0
0
128
701
0.92
0.40
1.5
2.6
—
—
—
0
0
48
208
1.16
0.40
1.3
2.1
—
—
—
0
0
14
52
1.35
0.40
1.6
1.9
—
—
—
0
0
380
2004
0.95
0.40
1.5
1.5
—
—
—
0
0
181
847
1.07
0.39
1.6
1.6
61.8
61.0
mu/l
0.02
156
776
1086
5311
1.03
0.39
2.6
2.9
68.1
69.6
e9/l
0.69
825
4151
28
170
0.83
0.39
1.4
1.3
16.1
6.8
u/ml
—
7
32
323
1541
1.05
0.39
1.1
1.1
1.8
1.1
u/ml
0.55
145
715
283
1503
0.95
0.39
3.3
4.2
—
—
—
0
0
312
1488
1.06
0.38
1.5
1.4
177.5
116.6
pmol/l
0.68
305
1443
13
48
1.36
0.38
1.0
1.1
0.7
1.7
u/ml
—
6
37
209
985
1.07
0.38
1.7
1.7
—
—
—
0
0
81
366
1.11
0.38
4.0
2.7
—
—
—
0
0
17
66
1.29
0.38
1.7
1.5
—
—
—
0
0
1046
5400
0.97
0.38
2.8
3.3
169.8
188.2
ng/l
0.78
933
4939
3648
18571
0.98
0.37
3.2
3.4
—
—
—
0
0
5
41
0.61
0.37
1.6
1.5
—
—
—
0
0
27
112
1.21
0.36
1.1
1.1
—
—
—
0
0
17
108
0.79
0.36
1.2
1.4
43.4
50.0
%
—
9
51
173
812
1.07
0.36
2.9
2.7
—
—
—
0
0
33
140
1.19
0.36
1.8
1.8
—
—
—
0
0
3183
15782
1.02
0.36
3.5
3.9
—
—
—
0
0
14
91
0.77
0.35
1.1
1.1
—
—
—
0
0
11
40
1.38
0.35
1.1
1.0
—
—
—
0
0
105
575
0.92
0.35
2.0
2.0
1.7
0.6
g/24h
—
7
27
6740
33617
1.01
0.35
4.7
5.3
0.0
0.0
estimate
0.07
1441
5902
139
752
0.93
0.35
2.7
3.9
56.4
57.3
%
0.15
95
468
6
22
1.37
0.35
2.5
2.0
—
—
—
0
0
6
22
1.37
0.35
1.0
1.0
—
—
—
0
0
6
45
0.67
0.34
1.0
1.0
—
—
—
0
0
6
45
0.67
0.34
1.0
1.0
—
—
—
0
0
6
45
0.67
0.34
1.0
1.0
—
—
—
0
0
1798
8871
1.02
0.34
2.6
3.2
22.7
23.0
%
0.42
1526
7395
151
707
1.07
0.34
2.1
1.9
32.2
32.6
pg
0.52
151
697
6
46
0.66
0.34
1.0
1.0
—
—
—
0
0
6
46
0.66
0.34
1.0
1.0
—
—
—
0
0
132
715
0.93
0.34
1.3
1.4
—
—
—
0
0
158
742
1.07
0.33
2.1
2.4
—
—
—
0
0
226
1074
1.06
0.33
1.2
1.2
—
—
—
0
0
37
215
0.86
0.33
2.3
2.0
103.9
110.4
ng/l
0.14
27
143
35
204
0.86
0.33
1.2
1.2
41.2
38.7
g/l
0.51
20
111
53
236
1.13
0.33
1.0
1.1
—
—
—
0
0
1074
5527
0.97
0.32
3.4
3.7
—
—
—
0
0
21
86
1.23
0.32
1.0
1.1
—
—
—
0
0
613
2985
1.03
0.32
4.4
6.0
24.7
24.7
mmol/l
0.08
579
2830
68
378
0.90
0.32
2.3
2.1
14.2
39.6
umol/l
—
6
43
24
144
0.84
0.32
2.4
2.4
—
—
—
0
0
390
2039
0.96
0.31
1.6
1.5
—
—
—
0
0
13
50
1.31
0.31
1.3
1.2
—
—
—
0
0
113
526
1.08
0.31
1.2
1.1
—
—
—
0
0
121
654
0.93
0.31
1.4
1.4
27262.1
106629.7
e6/l
2.31
76
440
1076
5529
0.98
0.30
1.3
1.5
—
—
—
0
0
607
3144
0.97
0.30
1.2
1.4
—
—
—
0
0
16
64
1.26
0.30
1.2
1.2
—
—
—
0
0
170
805
1.06
0.30
1.3
1.3
—
—
nmol/l
—
0
0
14
55
1.28
0.30
1.0
1.1
—
—
—
0
0
217
1148
0.95
0.29
1.3
1.4
—
—
—
0
0
8
30
1.34
0.29
1.0
1.2
—
—
—
0
0
1117
5496
1.02
0.29
2.6
3.1
10.5
10.4
g/l
0.35
1020
5087
433
2253
0.96
0.28
1.1
1.1
5.4
5.4
u/ml
0.01
51
312
904
4439
1.03
0.28
4.1
5.4
5.2
5.1
kpa
1.19
836
4139
19
115
0.83
0.28
1.5
1.5
29.8
69.6
g/l
0.40
12
97
159
847
0.94
0.28
3.7
4.4
—
—
—
0
0
50
280
0.90
0.28
1.1
1.1
589.7
1055.1
ng/l
0.30
13
53
109
588
0.93
0.28
1.1
1.2
—
—
—
0
0
1956
9978
0.98
0.28
2.1
2.8
29.9
29.6
s
1.65
1896
9669
55
306
0.90
0.27
1.1
1.2
4.2
12.3
u/ml
0.51
31
192
59
327
0.91
0.27
1.1
1.1
—
—
—
0
0
27
116
1.17
0.27
1.1
2.5
1.4
4.8
ug/l
0.79
11
68
134
632
1.07
0.27
3.0
3.6
—
—
—
0
0
41
232
0.89
0.27
2.0
1.6
135.0
126.8
au/ml
—
6
32
81
375
1.09
0.27
1.2
1.2
—
—
—
0
0
24
141
0.86
0.26
1.4
1.3
15.5
13.3
g/l
0.65
17
107
149
707
1.06
0.26
2.4
3.2
41.1
6.5
nmol/l
0.45
144
685
74
404
0.92
0.26
1.6
1.8
—
—
—
0
0
68
313
1.09
0.26
1.4
1.5
5.0
5.9
%
0.09
14
61
273
1317
1.04
0.25
2.3
2.6
16.4
16.4
%
0.00
121
682
60
330
0.91
0.25
2.0
1.7
—
—
—
0
0
877
4315
1.02
0.25
1.2
1.3
—
—
—
0
0
312
1511
1.04
0.25
1.1
1.1
2.4
2.9
u/ml
0.26
69
391
5
18
1.40
0.24
1.0
1.1
—
—
—
0
0
6443
32576
0.99
0.24
4.1
4.4
—
—
—
0
0
105
563
0.94
0.24
2.0
2.1
4.2
4.0
mg/l
0.09
100
536
10
64
0.79
0.24
1.0
1.1
—
—
—
0
0
892
4394
1.02
0.23
4.1
5.4
7.4
7.4
ph
0.79
94
467
323
1568
1.04
0.23
1.2
1.3
—
—
—
0
0
334
1623
1.04
0.23
1.1
1.1
6.6
6.2
u/ml
0.13
178
893
0
6
0.00
0.22
0.0
4.7
—
318.3
—
0
6
117
555
1.06
0.22
3.0
3.1
32.7
22.8
mu/l
0.72
110
523
776
3821
1.02
0.22
1.4
1.4
25.9
24.5
iu/l
0.51
651
3279
0
7
0.00
0.22
0.0
1.0
—
—
—
0
0
0
7
0.00
0.22
0.0
1.6
—
—
—
0
0
0
7
0.00
0.22
0.0
21.0
—
4.6
—
0
7
0
7
0.00
0.22
0.0
9.6
—
—
—
0
0
51
280
0.92
0.21
2.4
2.1
9.4
9.4
mg/l
0.02
39
231
12387
62396
0.99
0.21
15.0
15.2
40.3
38.8
%
82.09
9165
46388
568
2922
0.98
0.21
1.3
1.3
1.3
0.8
u/ml
0.37
47
236
48
263
0.92
0.20
2.0
2.5
—
—
—
0
0
36
163
1.11
0.20
3.2
2.1
—
—
—
0
0
223
1080
1.04
0.20
1.2
1.3
5.0
4.0
u/ml
0.27
97
510
1013
5174
0.98
0.19
3.9
5.4
85.5
99.7
ng/l
4.64
883
4560
6
26
1.16
0.19
1.0
1.1
—
—
—
0
0
116
614
0.95
0.19
1.2
1.2
—
—
—
0
0
39
178
1.10
0.19
2.9
3.2
—
—
—
0
0
39
178
1.10
0.19
5.8
6.5
—
—
—
0
0
1894
9625
0.99
0.19
2.1
2.1
—
—
—
0
0
250
1215
1.03
0.19
3.4
4.1
—
—
—
0
0
44
241
0.92
0.18
1.2
1.4
—
—
—
0
0
7
30
1.17
0.18
1.0
1.1
—
—
—
0
0
166
801
1.04
0.18
1.5
1.3
299.2
318.4
pmol/l
0.32
132
654
24
136
0.89
0.18
13.1
14.0
0.4
0.3
umol/l
0.15
24
128
66
310
1.07
0.18
1.9
2.1
—
—
—
0
0
67
315
1.07
0.18
4.3
1.9
140.2
149.2
umol/l
0.09
38
152
5
34
0.74
0.17
1.0
1.3
—
—
—
0
0
369
1808
1.03
0.17
1.1
1.1
1.8
1.4
u/ml
0.23
149
774
8
33
1.22
0.17
1.1
1.1
—
—
—
0
0
161
842
0.96
0.17
1.6
1.5
58.7
54.3
%
0.65
96
531
1024
5073
1.02
0.17
2.5
3.1
66.9
66.3
g/l
1.88
939
4685
401
2064
0.98
0.17
1.9
1.7
39.6
42.1
nmol/l
1.21
387
2019
112
537
1.05
0.16
1.3
1.4
0.3
1.2
u/ml
1.91
46
246
24
135
0.89
0.16
1.3
1.4
77.8
105.2
mu/l
0.35
19
100
45
209
1.08
0.16
1.2
1.1
—
—
—
0
0
13
55
1.19
0.16
1.1
1.0
—
—
—
0
0
341
1757
0.97
0.16
1.2
1.3
—
—
—
0
0
229
1187
0.97
0.16
1.0
1.1
7.0
5.0
u/ml
0.62
85
505
95
454
1.05
0.16
1.2
1.2
—
—
—
0
0
33
151
1.10
0.16
1.0
1.1
—
—
—
0
0
83
440
0.95
0.16
1.3
1.4
1101.7
405.6
titre
—
6
32
106
558
0.95
0.16
4.8
5.8
11.5
11.2
%
0.36
106
558
1647
8362
0.99
0.15
1.5
1.4
—
—
—
0
0
236
1152
1.03
0.15
3.5
3.3
1212.1
493.6
u/ml
0.30
217
1041
90
475
0.95
0.15
1.2
1.2
—
—
—
0
0
31
142
1.10
0.15
1.8
4.6
160.2
47.1
u/l
—
10
49
45
243
0.93
0.14
3.0
2.7
28.8
28.1
umol/l
0.18
37
188
13
76
0.86
0.14
1.1
2.4
1.6
4.4
nmol/l
1.33
13
67
61
325
0.94
0.14
3.3
3.0
—
—
—
0
0
217
1122
0.97
0.14
1.5
1.6
68.3
65.8
mmol/l
0.30
182
896
313
1610
0.98
0.14
3.3
3.8
24.8
24.3
mmol/l
1.32
275
1420
11
65
0.85
0.14
3.5
3.0
—
—
—
0
0
217
1121
0.97
0.13
1.1
1.1
2.4
2.3
u/ml
0.11
90
565
34
185
0.92
0.13
1.2
1.2
—
—
—
0
0
206
1007
1.03
0.13
1.4
1.6
—
—
—
0
0
499
2466
1.02
0.13
3.8
3.8
0.3
0.3
g/l
0.33
203
1146
106
512
1.04
0.13
1.1
1.1
—
—
—
0
0
248
1277
0.98
0.12
1.3
1.3
—
—
—
0
0
32
174
0.92
0.12
1.1
1.3
—
—
—
0
0
32
174
0.92
0.12
1.1
1.3
—
—
—
0
0
32
174
0.92
0.12
1.1
1.3
—
—
—
0
0
11
47
1.18
0.12
2.9
2.4
—
—
—
0
0
117
568
1.04
0.11
1.1
1.1
4.8
2.6
u/ml
0.36
42
203
104
542
0.96
0.11
1.1
1.1
—
—
—
0
0
69
331
1.05
0.11
1.2
1.3
—
—
—
0
0
54
286
0.95
0.11
1.8
1.6
—
—
—
0
0
28
152
0.93
0.11
1.5
1.7
—
—
—
0
0
49
260
0.95
0.10
1.3
1.3
—
—
—
0
0
66
317
1.05
0.10
2.0
2.1
9.6
8.8
%
0.16
66
307
5
21
1.20
0.10
1.0
1.3
268.0
268.5
nmol/l
—
5
21
303
1495
1.02
0.10
1.3
1.2
49.9
44.8
u/ml
0.20
37
148
5
23
1.09
0.10
1.0
1.0
172.4
165.1
g/l
—
5
23
1192
5943
1.01
0.09
4.3
4.3
0.9
1.0
%
0.34
322
1723
28
151
0.93
0.09
1.0
1.1
—
—
—
0
0
28
151
0.93
0.09
1.0
1.1
—
—
—
0
0
28
151
0.93
0.09
1.0
1.1
—
—
—
0
0
553
2813
0.99
0.09
1.3
1.3
234.1
229.8
miu/ml
0.10
254
1278
12
53
1.14
0.09
1.2
1.1
—
—
—
0
0
21
97
1.09
0.09
1.2
1.3
—
—
—
0
0
21
97
1.09
0.09
1.0
1.2
—
—
—
0
0
13
73
0.89
0.08
1.1
1.2
—
—
—
0
0
67
324
1.04
0.08
1.7
1.6
3.0
4.5
nmol/l
0.60
54
271
526
2674
0.99
0.08
2.2
3.1
21.8
21.6
s
0.13
450
2324
7
32
1.10
0.08
1.4
4.0
—
0.0
—
0
5
53
278
0.96
0.08
1.1
1.1
—
—
—
0
0
6
37
0.81
0.08
4.7
5.8
429.3
492.0
umol/l
—
6
37
17
78
1.10
0.08
1.1
1.2
2.0
1.7
umol/24h
0.69
17
78
176
868
1.02
0.07
3.1
2.7
—
—
—
0
0
700
3489
1.01
0.07
2.4
2.4
—
—
—
0
0
517
2573
1.01
0.07
1.7
1.7
—
—
—
0
0
58
281
1.04
0.07
1.6
2.2
—
—
—
0
0
104
536
0.98
0.07
1.4
1.5
—
—
—
0
0
8
47
0.86
0.07
4.0
14.1
—
—
—
0
0
193
954
1.02
0.06
1.1
1.1
1.5
1.5
g/l
0.03
171
868
50
261
0.96
0.06
1.5
1.6
15.7
15.5
pmol/l
0.04
43
217
29
138
1.06
0.06
1.6
2.4
2.4
1.7
mmol/l
0.44
20
93
98
481
1.02
0.06
1.0
1.1
6.6
0.7
u/ml
0.43
12
88
83
428
0.97
0.06
1.3
1.3
66.4
70.8
titre
0.07
11
38
118
581
1.02
0.06
1.1
1.1
249.1
265.1
mg/l
0.33
101
521
98
504
0.98
0.06
1.0
1.1
—
—
—
0
0
287
1426
1.01
0.05
2.2
2.3
130.3
129.7
g/l
0.15
209
1098
77
397
0.97
0.05
2.8
4.1
—
—
—
0
0
23
109
1.06
0.05
1.4
1.2
22.7
108.6
titre
—
6
11
42
219
0.96
0.05
1.0
1.0
—
—
—
0
0
70
361
0.97
0.05
1.2
1.2
—
—
—
0
0
503
2547
0.99
0.05
1.5
1.5
9.4
9.3
u/l
0.06
413
2051
31
149
1.05
0.05
1.1
1.1
0.7
0.7
umol/24h
0.11
17
81
254
1263
1.01
0.04
1.0
1.1
4.0
3.6
u/ml
0.12
93
514
1683
8430
1.00
0.04
1.7
1.8
—
—
—
0
0
432
2188
0.99
0.04
1.6
1.8
0.2
0.2
g/l
0.17
408
2069
14
65
1.08
0.04
1.9
1.8
—
—
—
0
0
75
385
0.98
0.04
2.0
2.0
3.2
4.6
ug/l
0.85
68
341
29
140
1.04
0.03
1.3
1.2
783.6
142.0
ug/l
0.38
17
82
116
575
1.01
0.03
1.1
1.1
—
—
—
0
0
283
1412
1.01
0.03
2.6
2.6
0.8
0.8
nmol/l
0.60
229
1221
961
4814
1.00
0.03
2.7
3.2
—
—
—
0
0
85
421
1.01
0.02
1.4
1.7
33.5
34.7
mmol/l
0.21
76
362
20
96
1.05
0.02
1.0
1.1
—
—
—
0
0
20
105
0.96
0.02
3.5
3.1
—
—
—
0
0
132
657
1.01
0.02
1.1
1.1
—
—
—
0
0
22
115
0.96
0.02
1.0
1.1
23.6
5.5
u/ml
0.37
16
93
1771
8916
1.00
0.02
6.0
9.0
1.1
1.1
mmol/l
2.88
1652
8423
29
150
0.97
0.01
7.5
6.9
86.0
41.8
g/mol
0.60
23
141
676
3406
1.00
0.01
2.8
3.3
42.1
52.2
u/ml
0.59
646
3285
81
412
0.99
0.01
2.0
2.4
585.3
719.3
ml
1.99
49
289
447
2254
1.00
0.01
1.6
1.8
1.2
1.2
g/l
1.13
424
2138
112
558
1.01
0.01
1.1
1.1
18.7
5.2
u/ml
0.35
37
177
28
137
1.03
0.01
2.3
2.4
—
—
—
0
0
105
532
0.99
0.01
1.4
1.4
11.8
12.2
umol/l
0.21
100
513
21
102
1.03
0.01
2.2
2.2
2.8
3.2
ug/l
—
10
32
75
373
1.01
0.01
2.0
2.1
2.1
2.7
ug/l
0.80
67
311
275
1387
1.00
0.01
2.1
1.9
193.4
189.7
pmol/l
0.21
255
1323
363
1829
1.00
0.00
3.3
4.2
1.6
2.9
ratio
1.03
38
141
27
139
0.98
0.00
1.1
1.3
20.8
66.8
ng/l
2.57
16
87
47
233
1.01
0.00
3.2
2.8
—
—
—
0
0
355
1781
1.00
0.00
2.0
1.9
10.6
11.4
mg/l
0.83
326
1679
27
138
0.98
0.00
1.1
1.2
—
—
—
0
0
24
120
1.01
0.00
1.6
1.5
438894.8
53067.9
nmol/l
0.40
18
98
18
90
1.01
0.00
1.0
1.2
—
—
—
0
0
12
60
1.01
0.00
1.0
1.1
0.1
0.4
u/ml
—
5
24
41
207
1.00
0.00
1.3
1.4
35.8
38.7
%
0.19
26
139
68
341
1.00
0.00
1.4
1.1
403.9
329.0
u/l
0.17
61
299
134
671
1.00
0.00
1.1
1.2
—
—
—
0
0
28
143
0.98
0.00
1.3
1.4
—
—
—
0
0
374
1882
1.00
0.00
3.4
4.3
56.8
80.3
mg/l
0.38
304
1553
451
2264
1.00
0.00
2.1
2.6
413.9
427.2
ug/l
0.04
424
2107
39
195
1.01
0.00
1.2
1.3
—
—
—
0
0
198
997
1.00
0.00
1.9
1.8
640.0
7074.3
titre
—
5
35
63
318
1.00
0.00
1.8
2.5
505.1
505.0
min
0.00
43
251
27
134
1.01
0.00
1.3
1.8
112.8
127.0
ng/l
0.29
27
134
70
354
0.99
0.00
1.0
1.1
7.9
12.1
u/ml
—
10
59
374
1881
1.00
0.00
3.4
4.3
35.0
55.5
mg/l
2.73
305
1555
119
600
1.00
0.00
1.2
1.2
40.7
41.4
mg/l
0.05
97
524
12
58
1.04
0.00
1.3
1.3
39.4
24.0
%
—
5
10
83
418
1.00
0.00
1.0
1.0
—
—
—
0
0
6
31
0.97
0.00
1.8
1.8
—
—
—
0
0
6
32
0.94
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
8
41
0.98
0.00
2.5
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_CARIES_1_OPER_ONLYAVO and mortality.

Females

Parameter HR [95% CI] p-value
K11_CARIES_1_OPER_ONLYAVO 0.715 [0.61, 0.84] < 0.001
Birth year 0.999 [0.99, 1.01] 0.763

During the follow-up period (1.1.1998 — 31.12.2019), 17682 out of 947023 females with K11_CARIES_1_OPER_ONLYAVO died.

Males

Parameter HR [95% CI] p-value
K11_CARIES_1_OPER_ONLYAVO 0.752 [0.64, 0.89] < 0.001
Birth year 0.989 [0.98, 1.0] 0.014

During the follow-up period (1.1.1998 — 31.12.2019), 22048 out of 814009 males with K11_CARIES_1_OPER_ONLYAVO died.

Mortality risk

Mortality risk for people of age

years, who have K11_CARIES_1_OPER_ONLYAVO.

N-year risk Females Males
1 0.071% 0.107%
5 0.482% 0.842%
10 1.062% 2.137%
15 2.169% 4.107%
20 3.87% 7.219%

Relationships between endpoints

Index endpoint: K11_CARIES_1_OPER_ONLYAVO – Dental caries 1 and operation codes, only avohilmo

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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