No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
4840 |
6. Filter based on genotype QC (FinnGen only) |
4840 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Retinal vascular disorders
based on the number of shared cases.
Similar with more cases:
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 40211 | 19929 | 20010 |
| Only index persons | 35002 | 17754 | 17248 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.56 | 0.57 | 0.56 |
| Only index persons | 0.66 | 0.65 | 0.66 |
| Median age at first event (years) | |||
| Whole population | 71.58 | 73.65 | 69.53 |
| Only index persons | 71.40 | 73.38 | 69.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4840 | 2157 | 2683 |
| Unadjusted period prevalence (%) | 0.98 | 0.74 | 1.18 |
| Median age at first event (years) | 69.40 | 69.00 | 69.73 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4355
- Matched controls
- 43560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
178.9
323.0
406
25
CKC12
NOMESCO Finland
Photocoagulation of retina
238.7
323.0
768
39
XCD20
NOMESCO Finland
Photoangiography of eye
129.0
323.0
420
36
H34.8
ICD-10 Finland
Other retinal vascular occlusions
4503599627370496.0
323.0
3065
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
12.9
323.0
815
766
H34.2
ICD-10 Finland
Other retinal artery occlusions
7844.8
323.0
677
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
14.4
323.0
1174
1090
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
754.3
323.0
1363
26
XCK10
NOMESCO Finland
Photography of fundus of eye
7.1
323.0
1084
1942
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.5
323.0
1191
1853
H34.1
ICD-10 Finland
Central retinal artery occlusion
3741.3
323.0
662
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
30.7
273.0
370
131
S01ED51
ATC
timolol, combinations; ophthalmic
5.6
258.8
845
1799
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
40.6
227.9
289
76
CKC10
NOMESCO Finland
Local photocoagulation of retina
119.3
219.6
237
21
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
253.6
212.9
217
9
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
24.7
207.2
298
129
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
1051.8
206.9
201
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.7
206.3
1071
3526
114
Kela drug reimbursment
Glaucoma
4.1
201.2
896
2575
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.7
199.0
1042
3442
XCK00
NOMESCO Finland
Perimetry
4.8
171.3
627
1468
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
64.7
170.1
198
32
CKC15
NOMESCO Finland
Panretinal photocoagulation
420.4
163.6
163
*
WX140
NOMESCO Finland
Parabulbar anesthesy
8.9
157.2
351
424
S01EE01
ATC
latanoprost; ophthalmic
4.3
149.5
612
1590
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
1439.6
142.5
138
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
361.1
140.6
141
*
H3601, E113
ICD-10 Finland
NA
+∞
140.3
134
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
161.8
134.2
141
9
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
7.3
131.9
334
489
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
125.6
1957
11791
H33.3
ICD-10 Finland
Retinal breaks without detachment
422.7
124.4
124
*
S01EC01
ATC
acetazolamide; systemic
8.4
123.8
286
363
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
4.6
122.8
467
1118
XCH00
NOMESCO Finland
Eye pressure measurement
5.8
118.0
356
658
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.1
114.9
1860
11254
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
25.1
112.3
160
66
ZX198
NOMESCO Finland
Other local administration
26.4
109.0
153
60
H3600, E113
ICD-10 Finland
NA
+∞
108.8
104
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.1
108.6
1669
9801
S01EC04
ATC
brinzolamide; ophthalmic
4.8
103.1
369
825
CKD40
NOMESCO Finland
Endophotocoagulation of retina
95.8
101.5
112
12
AA1AD
NOMESCO Finland
CT of head and brain
2.1
86.8
1370
7953
CKC20
NOMESCO Finland
Cryopexy of undetached retina
183.7
86.5
90
5
H43.8
ICD-10 Finland
Other disorders of vitreous body
3.2
85.5
497
1684
H53.1
ICD-10 Finland
Subjective visual disturbances
3.9
85.4
380
1042
H40.0
ICD-10 Finland
Glaucoma suspect
3.2
85.0
495
1680
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
290.5
83.9
85
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
82.8
1911
12752
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
823.6
82.8
81
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
7.7
80.9
195
263
ZXA10
NOMESCO Finland
Bilateral
2.2
80.8
992
5140
H3603, E113
ICD-10 Finland
NA
+∞
79.4
76
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.4
79.3
421
1332
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
79.2
2969
23243
S01ED01
ATC
timolol; ophthalmic
4.1
78.4
327
845
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
21.1
78.1
117
57
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
5.3
77.4
250
497
H34.0
ICD-10 Finland
Transient retinal artery occlusion
+∞
75.2
72
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
5.4
70.9
225
438
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
98.0
70.1
77
8
H36.01
ICD-10 Finland
Diabetic maculopathy
127.1
70.1
75
6
B01AC04
ATC
clopidogrel; oral
2.1
69.1
1006
5552
H36.00
ICD-10 Finland
Diabetic background retinopathy
58.2
67.9
80
14
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.6
67.5
322
932
1LA05
NOMESCO Finland
NA
+∞
65.8
63
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
140.1
65.1
69
5
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
62.9
496
2027
H35.8
ICD-10 Finland
Other specified retinal disorders
164.9
62.1
65
*
C08CA01
ATC
amlodipine; oral
1.7
61.7
1868
13187
H26.4
ICD-10 Finland
After-cataract
2.4
59.9
549
2432
C10AA05
ATC
atorvastatin; oral
1.7
58.7
1936
13947
H35.6
ICD-10 Finland
Retinal haemorrhage
152.0
57.0
60
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
7.3
56.5
140
197
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
3.9
56.5
245
653
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
33.7
55.8
73
22
S01EA03
ATC
apraclonidine; ophthalmic
10.1
54.8
111
112
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
185.6
53.0
55
*
S01EX03
ATC
NA
4.1
53.0
216
544
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.2
51.8
204
498
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
51.3
463
2024
S01EE03
ATC
bimatoprost; ophthalmic
4.4
51.0
194
458
CS494
NOMESCO Finland
Other visual field testing
4.8
49.9
173
371
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
49.9
2013
15084
S01EE05
ATC
tafluprost; ophthalmic
3.6
49.4
237
687
H3603, E103
ICD-10 Finland
NA
+∞
49.0
47
*
S01EC03
ATC
dorzolamide; ophthalmic
5.2
48.8
156
306
H35.36
ICD-10 Finland
Macular cyst
+∞
48.0
46
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.2
47.8
119
169
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
15.5
47.1
78
51
G45.3
ICD-10 Finland
Amaurosis fugax
4.7
46.9
167
369
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
462.5
46.4
46
*
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
75.3
46.0
52
7
Z3231
NOMESCO Finland
Registered nurse
1.7
46.0
1213
8036
37703
ICD-8 Finland
Other diseases of retina and optic nerve, Thrombosis venae centralis retinae
+∞
45.9
44
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.0
45.9
629
3327
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.3
45.5
450
2058
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
44.4
1078
6955
ZXA05
NOMESCO Finland
Left side
1.7
44.1
1197
7974
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
39.8
43.8
55
14
H54.4
ICD-10 Finland
Blindness, monocular
26.4
43.3
60
23
H35.37
ICD-10 Finland
Macular holes
431.8
43.3
43
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
10.7
41.9
82
78
H3600, E103
ICD-10 Finland
NA
+∞
41.7
40
*
C10AA01
ATC
simvastatin; oral
1.5
41.4
2244
17755
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.7
41.1
90
105
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.5
40.8
199
585
ZXA00
NOMESCO Finland
Right side
1.6
40.8
1247
8552
H3601, E103
ICD-10 Finland
NA
+∞
40.7
39
*
Z5132
NOMESCO Finland
Nursing associate professional
16.9
40.7
65
39
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
38.9
39.7
50
13
3623C
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO VENAE CENTRALIS RETINAE]
+∞
39.6
38
*
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
4.4
39.5
149
349
H25.8
ICD-10 Finland
Other senile cataract
1.9
38.9
617
3437
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.6
38.7
76
73
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
38.6
37
*
H53.4
ICD-10 Finland
Visual field defects
4.1
38.4
154
383
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.9
38.2
166
443
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
134.5
37.7
40
*
S01EE04
ATC
travoprost; ophthalmic
3.7
36.0
165
461
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
68.8
36.0
41
6
H40.9
ICD-10 Finland
Glaucoma, unspecified
4.1
35.7
144
360
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
35.7
1234
8673
N02BE01
ATC
paracetamol; systemic, rectal
1.6
35.4
3551
31800
C07AB07
ATC
bisoprolol; oral
1.5
34.7
2265
18365
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
14.7
34.5
58
40
H25.0
ICD-10 Finland
Senile incipient cataract
2.3
34.4
336
1522
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.4
34.2
316
1392
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
11.2
34.1
65
59
S01BC03
ATC
diclofenac; ophthalmic
4.1
33.9
138
348
A10AE04
ATC
insulin glargine; parenteral
2.1
33.3
408
2046
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
33.2
535
2987
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.5
33.2
286
1213
F05
ICPC
Visual disturbance other
3.7
33.0
149
412
S01BC05
ATC
ketorolac; ophthalmic
2.6
32.8
246
968
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.2
32.0
173
551
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
15.9
32.0
52
33
C03CA01
ATC
furosemide; systemic
1.5
31.9
1620
12370
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.3
31.6
322
1486
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.0
31.1
128
327
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
315.0
30.9
31
*
205
Kela drug reimbursment
Chronic hypertension
1.5
30.5
1502
11364
3623A
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO ARTERIAE CENTRALIS RETINAE]
+∞
30.2
29
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
32.8
30.0
39
12
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.1
29.9
121
304
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
29.9
852
5657
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
68.4
29.9
34
5
CKD15
NOMESCO Finland
Injection of vitreous substitute
156.0
29.7
31
*
A10AA01
ATC
NA
5.7
29.5
86
153
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
29.5
481
2689
H33.5
ICD-10 Finland
Other retinal detachments
15.8
28.9
47
30
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
293.8
28.8
29
*
T90
ICPC
Diabetes non-insulin dependent
1.6
28.6
1003
7008
WX002
NOMESCO Finland
Sedation and analgesia
1.6
28.5
819
5442
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.7
27.8
125
345
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
27.7
1238
9131
H35.9
ICD-10 Finland
Retinal disorder, unspecified
145.9
27.6
29
*
A10AA02
ATC
NA
3.6
27.2
126
357
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
27.2
1077
7729
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
27.1
731
4768
C08CA13
ATC
lercanidipine; oral
1.7
27.1
633
3969
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
27.0
349
1786
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
6.0
27.0
75
126
WX110
NOMESCO Finland
Local anesthesy
1.4
26.8
2371
19943
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
9.4
26.6
55
59
A10AE05
ATC
insulin detemir; parenteral
2.4
25.9
225
957
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
25.7
909
6339
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
25.4
1217
9072
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
25.1
805
5476
F29
ICPC
Eye symptom/complaint other
2.0
24.6
314
1596
CKD20
NOMESCO Finland
Removal of vitreous body substitute
130.7
24.6
26
*
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.0
24.2
98
248
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
56.3
24.0
28
5
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.7
23.8
577
3644
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.3
23.7
121
371
B01AA03
ATC
warfarin; systemic
1.5
23.1
1123
8363
S01ED02
ATC
betaxolol; ophthalmic
4.2
23.0
88
212
A98
ICPC
Health maint/preventive medicine
1.5
22.8
3679
34040
PA6AD
NOMESCO Finland
CT of neck arteries
4.3
22.7
85
200
CHD00
NOMESCO Finland
Laser trabeculoplasty
3.8
22.7
97
258
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
22.7
328
1750
A10BA02
ATC
metformin; oral
1.4
22.6
1219
9263
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
22.0
357
1986
H04AA01
ATC
glucagon; nasal, parenteral
5.9
21.8
61
104
H35.4
ICD-10 Finland
Peripheral retinal degeneration
62.8
21.8
25
*
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
38.8
21.7
27
7
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
115.6
21.6
23
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
21.5
1241
9532
J01DB01
ATC
cefalexin; oral
1.4
21.4
3098
27805
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
13.3
21.4
37
28
T89
ICPC
Diabetes insulin dependent
3.3
21.3
108
330
SPAT1263
SPAT
Sampling
1.4
21.3
1629
13153
A02BC02
ATC
pantoprazole; systemic
1.4
21.3
2582
22486
XCW10
NOMESCO Finland
Assessment of vision
8.9
21.3
45
51
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.8
21.2
361
2041
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
20.9
805
5695
37702
ICD-8 Finland
Other diseases of retina and optic nerve, Embolia, spasmus arteriae centralis retinae
+∞
20.8
20
*
3623B
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO RAMI ARTERIAE CENTRALIS RETINAE]
+∞
20.8
20
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
8.9
20.8
44
50
C09CA01
ATC
losartan; oral
1.4
20.8
1025
7632
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.4
20.6
102
307
H53.8
ICD-10 Finland
Other visual disturbances
5.2
20.5
64
125
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
20.5
928
6789
A11CC03
ATC
alfacalcidol; systemic
3.0
20.0
117
397
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
19.9
444
2731
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
19.8
1209
9350
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
19.8
19
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.9
19.8
285
1518
C09AA05
ATC
ramipril; oral
1.4
19.8
1179
9083
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
19.7
404
2425
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.7
19.7
402
2410
C01DA14
ATC
isosorbide mononitrate; oral
1.5
19.5
905
6645
L28
ICPC
Limited function/disability (L)
1.5
19.5
722
5056
C02AC05
ATC
moxonidine; oral
2.1
19.4
219
1059
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
19.1
1027
7750
Z2221
NOMESCO Finland
Medical doctor
1.4
19.0
1011
7614
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.1
19.0
60
119
S01EB01
ATC
pilocarpine; ophthalmic
4.6
18.4
64
141
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
18.2
844
6179
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
18.2
108
371
H26.2
ICD-10 Finland
Complicated cataract
5.4
18.1
54
101
R06.0
ICD-10 Finland
Dyspnoea
1.4
17.8
1033
7892
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
17.8
1005
7642
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
17.6
1081
8337
1LA04
NOMESCO Finland
NA
95.4
17.6
19
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
180.6
17.5
18
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
17.5
717
5117
K78
ICPC
Atrial fibrillation/flutter
1.6
17.3
423
2669
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
17.2
111
402
WX142
NOMESCO Finland
Sub-tenon anesthesy
11.1
17.2
32
29
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
9.8
17.1
34
35
B01AB05
ATC
enoxaparin; parenteral
1.4
17.1
1230
9738
H20.1
ICD-10 Finland
Chronic iridocyclitis
5.2
17.0
52
100
S18
ICPC
Laceration/cut
1.3
16.9
1614
13354
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
4.7
16.8
57
123
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
16.7
820
6063
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
16.6
1151
9045
H40.11
ICD-10 Finland
Low pressure glaucoma
2.7
16.5
111
413
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
16.5
600
4171
AN1
HP
Coronary angiography
1.5
16.4
595
4131
H02AB06
ATC
prednisolone; systemic
1.3
16.3
1806
15248
R42
ICD-10 Finland
Dizziness and giddiness
1.4
16.2
910
6894
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
16.0
163
754
C07AB02
ATC
metoprolol; systemic
1.4
16.0
1020
7898
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.6
16.0
46
83
PAW37
NOMESCO Finland
Biopsy of temporal artery
4.3
15.9
59
140
SPAT1262
SPAT
Handing over of treatment supplies
1.4
15.8
741
5426
H47.1
ICD-10 Finland
Papilloedema, unspecified
8.3
15.7
34
41
C09AA02
ATC
enalapril; systemic
1.4
15.7
928
7093
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
3.7
15.6
68
186
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
15.6
15
*
J01CA04
ATC
amoxicillin; systemic
1.3
15.5
2890
26151
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
15.4
259
1460
C08CA02
ATC
felodipine; oral
1.6
15.2
464
3095
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.1
15.2
85
282
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
15.2
1351
11015
TK800
NOMESCO Finland
Hemodialysis
2.8
15.0
97
353
A10BH05
ATC
linagliptin; oral
1.9
14.9
232
1271
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.0
14.9
194
996
A46
ICD-10 Finland
Erysipelas
1.5
14.8
584
4123
C09CA06
ATC
candesartan; oral
1.4
14.8
780
5830
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
14.8
1173
9391
F99
ICPC
Eye/adnexa disease other
5.4
14.6
43
80
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.5
14.6
114
464
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.4
14.5
71
214
H33.4
ICD-10 Finland
Traction detachment of retina
150.4
14.5
15
*
C10AA07
ATC
rosuvastatin; oral
1.4
14.2
918
7105
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
3.7
14.2
61
166
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
14.1
1118
8933
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.4
14.1
67
198
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
8.0
14.0
31
39
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
3.9
13.8
56
145
R53
ICD-10 Finland
Malaise and fatigue
1.4
13.8
799
6067
A12AA04
ATC
calcium carbonate; oral
3.1
13.8
74
240
ZXD05
NOMESCO Finland
Urgent procedure
1.3
13.7
1135
9124
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
13.7
1186
9599
127
Kela drug reimbursment
Transplant complication
3.8
13.7
58
156
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
13.7
1358
11206
M79.6
ICD-10 Finland
Pain in limb
1.3
13.7
1212
9841
137
Kela drug reimbursment
Uraemia requiring dialysis
5.1
13.6
42
83
L04AA06
ATC
mycophenolic acid; systemic
3.5
13.6
62
178
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
1.8
13.5
234
1332
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
13.5
13
*
CHD99
NOMESCO Finland
Other filtering operation
8.3
13.5
29
35
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.0
13.5
42
84
CKC60
NOMESCO Finland
Local buckling of sclera using implant
140.4
13.4
14
*
CKD50
NOMESCO Finland
Endodiathermy of retina
140.4
13.4
14
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
140.4
13.4
14
*
J01FF01
ATC
clindamycin; systemic
1.4
13.4
922
7196
J01AA02
ATC
doxycycline; systemic
1.3
13.3
2965
27141
N18.0
ICD-10 Finland
End-stage renal disease
3.3
13.3
65
197
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.5
13.3
417
2800
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
13.2
264
1573
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.4
13.2
611
4450
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.5
13.1
419
2823
B03XA02
ATC
darbepoetin alfa; parenteral
2.7
12.9
89
337
207
Kela drug reimbursment
Chronic arrhythmias
1.4
12.9
708
5316
Z94.0
ICD-10 Finland
Kidney transplant status
4.6
12.9
44
97
H44.0
ICD-10 Finland
Purulent endophthalmitis
19.1
12.9
19
10
H57.1
ICD-10 Finland
Ocular pain
2.5
12.9
99
398
H40.8
ICD-10 Finland
Other glaucoma
7.7
12.8
29
38
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
12.8
703
5281
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
50.1
12.8
15
*
SPAT1325
SPAT
Vaccination
1.3
12.8
1432
11984
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.5
12.8
422
2860
SPAT1009
SPAT
Measurement of intraocular pressure
3.0
12.7
73
246
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
12.7
1590
13507
N18.8
ICD-10 Finland
Other chronic renal failure
2.1
12.5
138
662
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
12.5
237
1386
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
12.5
2165
19125
K85
ICPC
Elevated blood pressure
1.4
12.5
609
4475
B05DA
ATC
Isotonic solutions
5.9
12.5
34
58
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.1
12.5
66
212
H3602, E113
ICD-10 Finland
NA
+∞
12.5
12
*
Z2446
NOMESCO Finland
Social worker
1.8
12.4
211
1192
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
12.3
601
4420
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.0
12.3
148
739
ZXE00
NOMESCO Finland
One hour or less
1.3
12.2
1402
11763
C03DA01
ATC
spironolactone; oral
1.5
12.1
481
3400
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.4
12.1
546
3956
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
12.0
477
3368
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
12.0
1202
9898
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
11.9
1657
14228
A28
ICPC
Limited function/disability NOS
1.4
11.8
722
5516
H16.0
ICD-10 Finland
Corneal ulcer
2.0
11.8
142
709
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
5.9
11.8
32
55
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
11.7
649
4880
D64.9
ICD-10 Finland
Anaemia, unspecified
1.5
11.7
455
3202
H54.5
ICD-10 Finland
Severe visual impairment, monocular
6.9
11.6
28
41
I50.0
ICD-10 Finland
Congestive heart failure
1.5
11.5
387
2634
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
11.5
1267
10549
CHC05
NOMESCO Finland
Iridotomy
2.6
11.5
81
314
M04AA01
ATC
allopurinol; systemic
1.4
11.5
601
4474
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
11.5
11
*
C10AA04
ATC
fluvastatin; oral
1.5
11.4
420
2914
Z49.2
ICD-10 Finland
Other dialysis
5.4
11.4
33
61
R50.9
ICD-10 Finland
Fever, unspecified
1.4
11.4
489
3502
3656C
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA NEOVASCULARE]
120.3
11.4
12
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.8
11.4
37
78
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
3.6
11.4
50
140
SPAT1301
SPAT
No procedures
1.3
11.4
1240
10309
H40
ICD-10 Finland
Glaucoma
3.1
11.4
62
205
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
11.3
409
2831
C10AX09
ATC
ezetimibe; oral
1.5
11.3
415
2881
CKA10
NOMESCO Finland
Biopsy of vitreous body
35.1
11.3
14
*
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.4
11.2
90
374
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
11.1
458
3253
R04.0
ICD-10 Finland
Epistaxis
1.6
11.1
323
2126
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
11.0
501
3633
Z49.0
ICD-10 Finland
Preparatory care for dialysis
3.8
10.9
45
120
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
10.9
527
3865
H46
ICD-10 Finland
Optic neuritis
5.3
10.9
32
61
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
10.8
345
2322
H44.5
ICD-10 Finland
Degenerated conditions of globe
11.9
10.8
19
16
L17
ICPC
Foot/toe symptom/complaint
1.3
10.8
883
7048
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.6
10.8
300
1956
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.6
10.7
30
54
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.7
1559
13413
H21.0
ICD-10 Finland
Hyphaema
6.7
10.6
26
39
H54.1
ICD-10 Finland
Severe visual impairment, binocular
12.9
10.6
18
14
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
10.6
228
1389
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
10.6
353
2401
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.2
10.6
100
451
SPAT1254
SPAT
Administration of medicine
1.4
10.6
596
4487
V03AE02
ATC
sevelamer; oral
6.0
10.6
28
47
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.8
10.5
193
1122
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
10.5
362
2479
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
10.5
923
7440
R51.80
ICD-10 Finland
Headache
1.5
10.4
378
2619
K02.1
ICD-10 Finland
Caries of dentine
1.2
10.4
1636
14179
H34
ICD-10 Finland
Retinal vascular occlusions
110.3
10.4
11
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
10.4
10
*
H35.29
ICD-10 Finland
Other proliferative retinopathy
+∞
10.4
10
*
H47.2
ICD-10 Finland
Optic atrophy
5.9
10.4
28
48
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.5
10.4
377
2611
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
10.4
671
5169
S01FA01
ATC
atropine; ophthalmic
5.1
10.3
31
61
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
10.3
274
1769
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
10.6
10.3
19
18
R55
ICD-10 Finland
Syncope and collapse
1.4
10.2
453
3266
S97
ICPC
Chronic ulcer skin
1.7
10.2
222
1356
I65.3
ICD-10 Finland
Occlusion and stenosis of multiple and bilateral precerebral arteries
7.5
10.2
23
31
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
2.9
10.1
60
210
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
6.2
10.1
26
42
196
Kela drug reimbursment
Paricalcitol and cinacalcet
5.9
10.1
27
46
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.8
10.1
63
226
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.8
10.1
159
881
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
6.9
10.1
24
35
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
2.4
10.1
79
326
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
2.4
10.0
81
337
I25.2
ICD-10 Finland
Old myocardial infarction
1.5
10.0
348
2391
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
4.2
9.9
36
86
C08CA05
ATC
nifedipine; systemic
1.5
9.9
296
1965
CHD35
NOMESCO Finland
Laser goniopuncture
4.9
9.9
31
64
I20.09
ICD-10 Finland
Unstable angina
1.6
9.8
265
1716
R02
ICPC
Shortness of breath/dyspnoea
1.4
9.8
439
3174
A10AE06
ATC
insulin degludec; parenteral
2.5
9.7
71
283
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
3.5
9.7
44
128
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
9.7
1069
8867
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
2.2
9.6
96
447
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
11.4
9.5
17
15
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1.7
9.5
197
1189
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
9.4
606
4658
1BA01
NOMESCO Finland
NA
100.2
9.4
10
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
9.4
1564
13601
H36.8*I70.8
ICD-10 Finland
Atherosclerotic retinopathy
+∞
9.4
9
*
H3602, E103
ICD-10 Finland
NA
+∞
9.4
9
*
H3603, E107
ICD-10 Finland
NA
+∞
9.4
9
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
9.4
391
2785
R03AC02
ATC
salbutamol; inhalant
1.2
9.4
1726
15176
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.6
9.3
228
1441
B01AF02
ATC
apixaban; oral
1.4
9.3
431
3134
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.5
9.3
280
1859
V03AE03
ATC
lanthanum carbonate; oral
6.9
9.3
22
32
N03AX16
ATC
pregabalin; oral
1.3
9.3
792
6349
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
9.3
387
2758
N19
ICD-10 Finland
Unspecified kidney failure
1.8
9.2
161
924
C09DA01
ATC
losartan and diuretics; oral
1.4
9.2
397
2846
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.3
9.2
32
74
EBA00
NOMESCO Finland
Extraction of tooth
1.3
9.1
998
8261
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
2.0
9.1
108
538
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
8.3
9.0
19
23
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
4.1
9.0
33
80
UJF32
NOMESCO Finland
Coloscopy
1.3
9.0
975
8058
H33.2
ICD-10 Finland
Serous retinal detachment
36.7
9.0
11
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
3.9
9.0
35
90
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
1.6
8.9
235
1513
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.0
8.9
27
54
R4110
NOMESCO Finland
Physiotherapy
1.3
8.9
937
7715
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
6.1
8.9
23
38
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.8
8.8
139
770
V03AE01
ATC
polystyrene sulfonate; oral
2.7
8.8
60
228
C09CA03
ATC
valsartan; oral
1.5
8.8
337
2361
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.4
8.8
527
4001
WX872
NOMESCO Finland
Intensive care
1.6
8.8
197
1217
ZXD20
NOMESCO Finland
Day surgery
1.4
8.8
409
2978
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
8.8
538
4105
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.8
1051
8790
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
6.3
8.8
22
35
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
5.1
8.7
26
51
B05DB
ATC
Hypertonic solutions
5.1
8.7
26
51
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
1.6
8.7
196
1211
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
8.7
697
5531
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.6
8.7
228
1466
XCH05
NOMESCO Finland
Eye pressure longterm registration
3.3
8.6
42
130
H44.1
ICD-10 Finland
Other endophthalmitis
16.3
8.5
13
8
NHQ40
NOMESCO Finland
Amputation of toe
2.4
8.5
70
298
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.6
8.5
241
1580
J01MA12
ATC
levofloxacin; systemic
1.3
8.5
712
5686
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.0
8.5
46
154
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
1.5
8.5
265
1780
H43.3
ICD-10 Finland
Other vitreous opacities
3.1
8.4
43
138
F01
ICPC
Eye pain
2.2
8.4
77
346
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
8.4
539
4145
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
4.8
8.3
26
54
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
8.3
1550
13592
L04AX01
ATC
azathioprine; systemic
1.8
8.3
125
686
Z71.8
ICD-10 Finland
Other specified counselling
1.3
8.3
690
5508
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
7.1
8.2
19
27
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
1.8
8.2
128
707
81
HP
Angiography of the heart and coronary arteries
1.5
8.2
322
2269
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
8.2
255
1709
CD2S4
NOMESCO Finland
Photography of eye
4.5
8.1
27
60
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
7.5
8.1
18
24
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
8.1
1030
8662
H05BX01
ATC
cinacalcet; oral
3.8
8.1
32
84
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
1.8
8.1
123
674
H01.0
ICD-10 Finland
Blepharitis
1.8
8.1
142
819
M54.5
ICD-10 Finland
Low back pain
1.3
8.1
980
8198
C09DA06
ATC
candesartan and diuretics; oral
1.5
8.1
260
1756
A10BK03
ATC
empagliflozin; oral
1.6
8.1
216
1396
B01AC07
ATC
dipyridamole; systemic
1.5
8.0
258
1743
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
8.0
134
762
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
3.0
7.9
44
150
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
7.2
7.9
18
25
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
2.4
7.9
65
276
A10BB01
ATC
glibenclamide; oral
1.6
7.9
197
1251
WX290
NOMESCO Finland
Other blockade of nerve
1.2
7.9
1045
8829
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.3
7.9
689
5531
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
7.9
1386
12071
R60.0
ICD-10 Finland
Localized oedema
1.4
7.9
421
3142
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
5.1
7.8
23
45
E66.8
ICD-10 Finland
Other obesity
1.9
7.8
109
580
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
7.8
121
669
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
6.1
7.8
20
33
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
6.9
7.8
18
26
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
7.7
122
679
SPAT1310
SPAT
Counselling related to known health issue
1.2
7.7
1090
9269
3643
FHL
Vitrectomy through pars Plana
15.0
7.7
12
8
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
7.7
1394
12166
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.1
7.6
28
69
SPAT1153
SPAT
Removal of sutures
1.2
7.6
1153
9870
J01MA02
ATC
ciprofloxacin; systemic
1.2
7.6
1497
13166
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
7.6
583
4593
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
7.6
731
5936
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
2.5
7.6
57
232
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
7.6
1010
8526
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
18.4
7.6
11
6
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.6
1347
11727
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
25.0
7.6
10
*
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
25.0
7.6
10
*
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.5
1387
12119
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
8.8
7.5
15
17
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
7.5
703
5692
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.5
1824
16361
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
5.4
7.5
21
39
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
7.5
561
4409
H26.02
ICD-10 Finland
Presenil cataract
2.2
7.5
75
350
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
1.7
7.4
160
982
J01DA01
ATC
[U] cefalexin; systemic
1.2
7.4
2258
20673
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
6.4
7.4
18
28
Z3226
NOMESCO Finland
Physiotherapist
1.3
7.4
637
5105
WX199
NOMESCO Finland
Other local analgesia
1.9
7.4
97
506
I25
ICD-10 Finland
Chronic ischaemic heart disease
1.5
7.4
210
1382
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
7.4
535
4184
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.8
7.4
126
720
TK810
NOMESCO Finland
Hemofiltration
3.8
7.3
29
77
SPAT1216
SPAT
Assessment of functional ability
1.3
7.3
644
5172
CD1AE
NOMESCO Finland
Other special ultrasound examination of the eye
+∞
7.3
7
*
H35.20
ICD-10 Finland
Proliferative vitreoretinopathy
+∞
7.3
7
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
7.3
7
*
S01FA04
ATC
cyclopentolate; ophthalmic
2.9
7.3
42
146
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
2.6
7.3
48
183
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
7.3
496
3847
Z02.7
ICD-10 Finland
Issue of medical certificate
1.6
7.2
198
1290
A10BB12
ATC
glimepiride; oral
1.4
7.2
319
2301
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.6
7.2
169
1059
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
1.6
7.2
172
1084
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
3.9
7.1
27
69
N17.9
ICD-10 Finland
Acute renal failure, unspecified
1.6
7.1
157
967
C07AG02
ATC
carvedilol; oral
1.5
7.1
249
1716
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
3.8
7.1
28
74
WX213
NOMESCO Finland
Lower leg blockade
3.7
7.1
29
79
ZX120
NOMESCO Finland
Intravenous
1.4
7.1
326
2368
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
1.8
7.1
120
685
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.2
7.0
68
315
XKD00
NOMESCO Finland
Uroflowmetry
1.3
7.0
691
5628
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
3.1
7.0
35
112
R05
ICPC
Cough
1.3
7.0
667
5408
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
1.7
7.0
141
850
FXZ00
NOMESCO Finland
Off-pump cardiac operation
3.0
7.0
38
129
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
7.0
495
3858
G47.3
ICD-10 Finland
Sleep apnoea
1.3
7.0
611
4903
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
7.0
476
3691
P20
ICPC
Memory disturbance
1.3
7.0
571
4542
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
1.8
6.9
106
586
F28
ICPC
Limited function/disability (F)
3.6
6.9
29
81
PD5AD
NOMESCO Finland
CT of aorta
2.2
6.9
64
289
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
1.5
6.9
245
1693
K29
ICPC
Cardiovascular sympt/complt other
1.6
6.9
158
982
TKC20
NOMESCO Finland
Catheterisation of bladder
1.4
6.9
287
2046
I65.0
ICD-10 Finland
Occlusion and stenosis of vertebral artery
5.8
6.9
18
31
280
Kela drug reimbursment
Clopidogrel
2.0
6.9
79
395
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
3.2
6.9
33
103
M48.0
ICD-10 Finland
Spinal stenosis
1.3
6.9
487
3797
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
6.8
167
1058
-1
NOMESCO Finland
NA
1.2
6.8
874
7340
Z71.9
ICD-10 Finland
Counselling, unspecified
1.6
6.8
173
1107
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.0
6.8
76
375
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.8
1101
9482
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
6.1
6.8
17
28
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
6.1
6.8
17
28
H54
ICD-10 Finland
Visual impairment including blindness (binocular or monocular)
40.1
6.8
8
*
3711
FHL
Cyclodiateria or cryocoagulation
40.1
6.8
8
*
C03AA03
ATC
hydrochlorothiazide; oral
1.4
6.7
388
2929
A02BC05
ATC
esomeprazole; systemic
1.2
6.7
1390
12255
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
6.7
906
7658
XF404
NOMESCO Finland
Ambulatory ECG
1.4
6.7
347
2577
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.5
6.7
230
1581
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
6.7
585
4697
SPAT1260
SPAT
Consultation of another employee
1.3
6.7
615
4970
S01.0
ICD-10 Finland
Open wound of scalp
1.4
6.6
261
1843
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
1.7
6.6
116
671
H18.1
ICD-10 Finland
Bullous keratopathy
5.2
6.6
19
37
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.7
6.6
135
816
CFW99
NOMESCO Finland
Other operation on conjunctiva
5.9
6.6
17
29
TPX10
NOMESCO Finland
Implantation of vascular injection port
1.9
6.6
93
502
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
3.6
6.6
27
75
XCX10
NOMESCO Finland
Other photography of eye
8.7
6.5
13
15
S01AX11
ATC
[U] ofloxacin; ophthalmic
1.7
6.5
134
812
H02.4
ICD-10 Finland
Ptosis of eyelid
1.9
6.5
94
511
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
1.5
6.5
216
1474
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.9
6.5
24
61
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
3.6
6.5
27
76
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
1.7
6.4
120
708
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
5.3
6.4
18
34
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
5.7
6.4
17
30
A02BC03
ATC
lansoprazole; oral
1.2
6.4
1062
9152
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
69.9
6.4
7
*
SPAT1229
SPAT
Assessment of need for aid
1.4
6.4
318
2343
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
6.4
1029
8845
Z01.2
ICD-10 Finland
Dental examination
1.2
6.4
1105
9565
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.1
6.4
65
307
H03AA01
ATC
levothyroxine sodium; systemic
1.2
6.4
740
6146
H54.7
ICD-10 Finland
Unspecified visual loss
3.6
6.4
26
72
RS222
NOMESCO Finland
NA
2.5
6.4
46
186
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.2
6.3
823
6919
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.3
2213
20380
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
11.0
6.3
11
10
K90
ICPC
Stroke/cerebrovascular accident
1.7
6.3
120
713
XF402
NOMESCO Finland
ECG with work load test
1.3
6.3
408
3139
TK820
NOMESCO Finland
Peritoneal dialysis
4.6
6.3
20
44
A10BH01
ATC
sitagliptin; oral
1.4
6.3
354
2667
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.4
6.3
48
199
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
2.8
6.3
37
133
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
6.2
6
*
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
6.2
6
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
6.2
6
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
6.2
6
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
6.2
6
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
6.2
6
*
H3601, E1100
ICD-10 Finland
NA
+∞
6.2
6
*
G04CA02
ATC
tamsulosin; oral
1.2
6.2
1042
8987
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
26.7
6.2
8
*
A04
ICPC
Weakness/tiredness general
1.3
6.2
456
3571
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
6.2
826
6962
321
Kela drug reimbursment
Paricalcitol and cinacalcet
3.4
6.2
27
79
C10AA03
ATC
pravastatin; oral
1.4
6.2
296
2167
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
6.2
244
1726
S29
ICPC
Skin symptom/complaint other
1.3
6.2
558
4495
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.3
6.2
507
4034
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
5.0
6.2
18
36
H53
ICD-10 Finland
Visual disturbances
3.8
6.2
24
64
L03
ICPC
Low back symptom/complaint
1.2
6.1
712
5908
H43
ICD-10 Finland
Disorders of vitreous body
5.3
6.1
17
32
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.2
6.1
727
6051
S21
ICPC
Skin texture symptom/complaint
1.3
6.1
403
3110
ZX199
NOMESCO Finland
Other rote
7.7
6.1
13
17
-50
ICPC
Medication/prescr/renewal
1.6
6.1
150
957
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.5
6.1
179
1190
E66.00
ICD-10 Finland
Metabolic syndrome
1.6
6.1
146
923
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.5
6.1
198
1347
N02AX02
ATC
tramadol; systemic, rectal
1.2
6.0
1537
13769
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.4
6.0
256
1837
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
1.8
6.0
96
539
PE1AT
NOMESCO Finland
Femoral artery PTA
2.3
6.0
53
237
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
10.0
6.0
11
11
XF600
NOMESCO Finland
Bloodpressure measurement
1.5
6.0
215
1493
M10.9
ICD-10 Finland
Gout, unspecified
1.4
6.0
254
1818
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
1.6
6.0
149
953
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINAVASC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINAVASC | 1.176 [1.08, 1.28] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.188 |
During the follow-up period (1.1.1998 — 31.12.2019), 5684 out of 16352 females with H7_RETINAVASC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINAVASC | 1.27 [1.16, 1.4] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 5848 out of 16087 males with H7_RETINAVASC died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINAVASC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.111% | 0.292% |
| 5 | 0.693% | 1.433% |
| 10 | 1.673% | 3.927% |
| 15 | 3.183% | 7.02% |
| 20 | 5.727% | 12.282% |
Relationships between endpoints
↥Index endpoint: H7_RETINAVASC – Retinal vascular disorders
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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