Glaucoma

H7_GLAUCOMA

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H40-H42
Cause of death: ICD-10 H40-H42

13346

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

13346

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Check minimum number of events None

13346

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H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 13614 7855 5759
Unadjusted prevalence (%) 4.41 4.53 4.27
Mean age at first event (years) 63.27 62.78 63.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.44 [1.20, 1.72] 7.4e-5 1797
15 years 0.01 0.97 [0.84, 1.13] 7.3e-1 925
5 years 0.00 1.57 [1.37, 1.79] 5.3e-11 491
1 year 0.00 2.06 [1.66, 2.55] 3.5e-11 124

Correlations

Index endpoint: H7_GLAUCOMA – Glaucoma
GWS hits: 16

Survival analyses between endpoints

Plot

before Glaucoma
after Glaucoma

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